FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0937, 619 aa 1>>>pF1KA0937 619 - 619 aa - 619 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.9133+/-0.000358; mu= -1.6869+/- 0.022 mean_var=264.6305+/-54.070, 0's: 0 Z-trim(121.7): 46 B-trim: 0 in 0/61 Lambda= 0.078841 statistics sampled from 38669 (38715) to 38669 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.774), E-opt: 0.2 (0.454), width: 16 Scan time: 11.060 The best scores are: opt bits E(85289) NP_055992 (OMIM: 616110) E3 ubiquitin-protein liga ( 619) 4262 498.2 3.4e-140 XP_006718546 (OMIM: 616110) PREDICTED: E3 ubiquiti ( 513) 3508 412.4 1.9e-114 NP_001287656 (OMIM: 616110) E3 ubiquitin-protein l ( 513) 3508 412.4 1.9e-114 XP_011536311 (OMIM: 602582) PREDICTED: E3 ubiquiti ( 620) 1871 226.3 2.5e-58 NP_004407 (OMIM: 602582) E3 ubiquitin-protein liga ( 620) 1871 226.3 2.5e-58 XP_016867213 (OMIM: 613141) PREDICTED: probable E3 ( 622) 1316 163.2 2.5e-39 XP_005250188 (OMIM: 613141) PREDICTED: probable E3 ( 622) 1316 163.2 2.5e-39 XP_011514076 (OMIM: 613141) PREDICTED: probable E3 ( 622) 1316 163.2 2.5e-39 XP_016867214 (OMIM: 613141) PREDICTED: probable E3 ( 622) 1316 163.2 2.5e-39 XP_016867212 (OMIM: 613141) PREDICTED: probable E3 ( 622) 1316 163.2 2.5e-39 NP_001096065 (OMIM: 613141) probable E3 ubiquitin- ( 622) 1316 163.2 2.5e-39 NP_065943 (OMIM: 613141) probable E3 ubiquitin-pro ( 622) 1316 163.2 2.5e-39 XP_011514077 (OMIM: 613141) PREDICTED: probable E3 ( 622) 1316 163.2 2.5e-39 XP_011514075 (OMIM: 613141) PREDICTED: probable E3 ( 622) 1316 163.2 2.5e-39 XP_005250189 (OMIM: 613141) PREDICTED: probable E3 ( 622) 1316 163.2 2.5e-39 XP_011514074 (OMIM: 613141) PREDICTED: probable E3 ( 622) 1316 163.2 2.5e-39 NP_001096064 (OMIM: 613141) probable E3 ubiquitin- ( 622) 1316 163.2 2.5e-39 XP_016867215 (OMIM: 613141) PREDICTED: probable E3 ( 575) 1153 144.6 9.1e-34 XP_016867216 (OMIM: 613141) PREDICTED: probable E3 ( 575) 1153 144.6 9.1e-34 NP_001096066 (OMIM: 613141) probable E3 ubiquitin- ( 575) 1153 144.6 9.1e-34 XP_016867217 (OMIM: 613141) PREDICTED: probable E3 ( 568) 590 80.5 1.7e-14 NP_612144 (OMIM: 613143) E3 ubiquitin-protein liga ( 740) 508 71.3 1.3e-11 XP_016867219 (OMIM: 613141) PREDICTED: probable E3 ( 414) 502 70.4 1.4e-11 XP_016867218 (OMIM: 613141) PREDICTED: probable E3 ( 419) 502 70.4 1.4e-11 XP_011536324 (OMIM: 613142) PREDICTED: probable E3 ( 347) 424 61.5 5.6e-09 NP_001273175 (OMIM: 613142) probable E3 ubiquitin- ( 347) 424 61.5 5.6e-09 XP_005268760 (OMIM: 613142) PREDICTED: probable E3 ( 347) 424 61.5 5.6e-09 NP_848597 (OMIM: 613142) probable E3 ubiquitin-pro ( 347) 424 61.5 5.6e-09 XP_005268754 (OMIM: 613142) PREDICTED: probable E3 ( 350) 424 61.5 5.6e-09 XP_005268757 (OMIM: 613142) PREDICTED: probable E3 ( 350) 424 61.5 5.6e-09 XP_005268755 (OMIM: 613142) PREDICTED: probable E3 ( 350) 424 61.5 5.6e-09 NP_001273174 (OMIM: 613142) probable E3 ubiquitin- ( 350) 424 61.5 5.6e-09 >>NP_055992 (OMIM: 616110) E3 ubiquitin-protein ligase D (619 aa) initn: 4262 init1: 4262 opt: 4262 Z-score: 2638.0 bits: 498.2 E(85289): 3.4e-140 Smith-Waterman score: 4262; 100.0% identity (100.0% similar) in 619 aa overlap (1-619:1-619) 10 20 30 40 50 60 pF1KA0 MLLASAVVVWEWLNEHGRWRPYSPAVSHHIEAVVRAGPRAGGSVVLGQVDSRLAPYIIDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MLLASAVVVWEWLNEHGRWRPYSPAVSHHIEAVVRAGPRAGGSVVLGQVDSRLAPYIIDL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 QSMNQFRQDTGTLRPVRRNYYDPSSAPGKGVVWEWENDNGSWTPYDMEVGITIQHAYEKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 QSMNQFRQDTGTLRPVRRNYYDPSSAPGKGVVWEWENDNGSWTPYDMEVGITIQHAYEKQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 HPWIDLTSIGFSYVIDFNTMGQINRQTQRQRRVRRRLDLIYPMVTGTLPKAQSWPVSPGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 HPWIDLTSIGFSYVIDFNTMGQINRQTQRQRRVRRRLDLIYPMVTGTLPKAQSWPVSPGP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 ATSPPMSPCSCPQCVLVMSVKAAVVNGSTGPLQLPVTRKNMPPPGVVKLPPLPGSGAKPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ATSPPMSPCSCPQCVLVMSVKAAVVNGSTGPLQLPVTRKNMPPPGVVKLPPLPGSGAKPL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 DSTGTIRGPLKTAPSQVIRRQASSMPTGTTMGSPASPPGPNSKTGRVALATLNRTNLQRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 DSTGTIRGPLKTAPSQVIRRQASSMPTGTTMGSPASPPGPNSKTGRVALATLNRTNLQRL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 AIAQSRVLIASGVPTVPVKNLNGSSPVNPALAGITGILMSAAGLPVCLTRPPKLVLHPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 AIAQSRVLIASGVPTVPVKNLNGSSPVNPALAGITGILMSAAGLPVCLTRPPKLVLHPPP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 VSKSEIKSIPGVSNTSRKTTKKQAKKGKTPEEVLKKYLQKVRHPPDEDCTICMERLTAPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VSKSEIKSIPGVSNTSRKTTKKQAKKGKTPEEVLKKYLQKVRHPPDEDCTICMERLTAPS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 GYKGPQPTVKPDLVGKLSRCGHVYHIYCLVAMYNNGNKDGSLQCPTCKTIYGVKTGTQPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GYKGPQPTVKPDLVGKLSRCGHVYHIYCLVAMYNNGNKDGSLQCPTCKTIYGVKTGTQPP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 GKMEYHLIPHSLPGHPDCKTIRIIYSIPPGIQGPEHPNPGKSFSARGFPRHCYLPDSEKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GKMEYHLIPHSLPGHPDCKTIRIIYSIPPGIQGPEHPNPGKSFSARGFPRHCYLPDSEKG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 RKVLKLLLVAWDRRLIFAIGTSSTTGESDTVIWNEVHHKTEFGSNLTGHGYPDANYLDNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 RKVLKLLLVAWDRRLIFAIGTSSTTGESDTVIWNEVHHKTEFGSNLTGHGYPDANYLDNV 550 560 570 580 590 600 610 pF1KA0 LAELAAQGISEDSTAQEKD ::::::::::::::::::: NP_055 LAELAAQGISEDSTAQEKD 610 >>XP_006718546 (OMIM: 616110) PREDICTED: E3 ubiquitin-pr (513 aa) initn: 3508 init1: 3508 opt: 3508 Z-score: 2175.6 bits: 412.4 E(85289): 1.9e-114 Smith-Waterman score: 3508; 100.0% identity (100.0% similar) in 513 aa overlap (107-619:1-513) 80 90 100 110 120 130 pF1KA0 RRNYYDPSSAPGKGVVWEWENDNGSWTPYDMEVGITIQHAYEKQHPWIDLTSIGFSYVID :::::::::::::::::::::::::::::: XP_006 MEVGITIQHAYEKQHPWIDLTSIGFSYVID 10 20 30 140 150 160 170 180 190 pF1KA0 FNTMGQINRQTQRQRRVRRRLDLIYPMVTGTLPKAQSWPVSPGPATSPPMSPCSCPQCVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FNTMGQINRQTQRQRRVRRRLDLIYPMVTGTLPKAQSWPVSPGPATSPPMSPCSCPQCVL 40 50 60 70 80 90 200 210 220 230 240 250 pF1KA0 VMSVKAAVVNGSTGPLQLPVTRKNMPPPGVVKLPPLPGSGAKPLDSTGTIRGPLKTAPSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VMSVKAAVVNGSTGPLQLPVTRKNMPPPGVVKLPPLPGSGAKPLDSTGTIRGPLKTAPSQ 100 110 120 130 140 150 260 270 280 290 300 310 pF1KA0 VIRRQASSMPTGTTMGSPASPPGPNSKTGRVALATLNRTNLQRLAIAQSRVLIASGVPTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VIRRQASSMPTGTTMGSPASPPGPNSKTGRVALATLNRTNLQRLAIAQSRVLIASGVPTV 160 170 180 190 200 210 320 330 340 350 360 370 pF1KA0 PVKNLNGSSPVNPALAGITGILMSAAGLPVCLTRPPKLVLHPPPVSKSEIKSIPGVSNTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PVKNLNGSSPVNPALAGITGILMSAAGLPVCLTRPPKLVLHPPPVSKSEIKSIPGVSNTS 220 230 240 250 260 270 380 390 400 410 420 430 pF1KA0 RKTTKKQAKKGKTPEEVLKKYLQKVRHPPDEDCTICMERLTAPSGYKGPQPTVKPDLVGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RKTTKKQAKKGKTPEEVLKKYLQKVRHPPDEDCTICMERLTAPSGYKGPQPTVKPDLVGK 280 290 300 310 320 330 440 450 460 470 480 490 pF1KA0 LSRCGHVYHIYCLVAMYNNGNKDGSLQCPTCKTIYGVKTGTQPPGKMEYHLIPHSLPGHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LSRCGHVYHIYCLVAMYNNGNKDGSLQCPTCKTIYGVKTGTQPPGKMEYHLIPHSLPGHP 340 350 360 370 380 390 500 510 520 530 540 550 pF1KA0 DCKTIRIIYSIPPGIQGPEHPNPGKSFSARGFPRHCYLPDSEKGRKVLKLLLVAWDRRLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DCKTIRIIYSIPPGIQGPEHPNPGKSFSARGFPRHCYLPDSEKGRKVLKLLLVAWDRRLI 400 410 420 430 440 450 560 570 580 590 600 610 pF1KA0 FAIGTSSTTGESDTVIWNEVHHKTEFGSNLTGHGYPDANYLDNVLAELAAQGISEDSTAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FAIGTSSTTGESDTVIWNEVHHKTEFGSNLTGHGYPDANYLDNVLAELAAQGISEDSTAQ 460 470 480 490 500 510 pF1KA0 EKD ::: XP_006 EKD >>NP_001287656 (OMIM: 616110) E3 ubiquitin-protein ligas (513 aa) initn: 3508 init1: 3508 opt: 3508 Z-score: 2175.6 bits: 412.4 E(85289): 1.9e-114 Smith-Waterman score: 3508; 100.0% identity (100.0% similar) in 513 aa overlap (107-619:1-513) 80 90 100 110 120 130 pF1KA0 RRNYYDPSSAPGKGVVWEWENDNGSWTPYDMEVGITIQHAYEKQHPWIDLTSIGFSYVID :::::::::::::::::::::::::::::: NP_001 MEVGITIQHAYEKQHPWIDLTSIGFSYVID 10 20 30 140 150 160 170 180 190 pF1KA0 FNTMGQINRQTQRQRRVRRRLDLIYPMVTGTLPKAQSWPVSPGPATSPPMSPCSCPQCVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FNTMGQINRQTQRQRRVRRRLDLIYPMVTGTLPKAQSWPVSPGPATSPPMSPCSCPQCVL 40 50 60 70 80 90 200 210 220 230 240 250 pF1KA0 VMSVKAAVVNGSTGPLQLPVTRKNMPPPGVVKLPPLPGSGAKPLDSTGTIRGPLKTAPSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VMSVKAAVVNGSTGPLQLPVTRKNMPPPGVVKLPPLPGSGAKPLDSTGTIRGPLKTAPSQ 100 110 120 130 140 150 260 270 280 290 300 310 pF1KA0 VIRRQASSMPTGTTMGSPASPPGPNSKTGRVALATLNRTNLQRLAIAQSRVLIASGVPTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VIRRQASSMPTGTTMGSPASPPGPNSKTGRVALATLNRTNLQRLAIAQSRVLIASGVPTV 160 170 180 190 200 210 320 330 340 350 360 370 pF1KA0 PVKNLNGSSPVNPALAGITGILMSAAGLPVCLTRPPKLVLHPPPVSKSEIKSIPGVSNTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PVKNLNGSSPVNPALAGITGILMSAAGLPVCLTRPPKLVLHPPPVSKSEIKSIPGVSNTS 220 230 240 250 260 270 380 390 400 410 420 430 pF1KA0 RKTTKKQAKKGKTPEEVLKKYLQKVRHPPDEDCTICMERLTAPSGYKGPQPTVKPDLVGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKTTKKQAKKGKTPEEVLKKYLQKVRHPPDEDCTICMERLTAPSGYKGPQPTVKPDLVGK 280 290 300 310 320 330 440 450 460 470 480 490 pF1KA0 LSRCGHVYHIYCLVAMYNNGNKDGSLQCPTCKTIYGVKTGTQPPGKMEYHLIPHSLPGHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSRCGHVYHIYCLVAMYNNGNKDGSLQCPTCKTIYGVKTGTQPPGKMEYHLIPHSLPGHP 340 350 360 370 380 390 500 510 520 530 540 550 pF1KA0 DCKTIRIIYSIPPGIQGPEHPNPGKSFSARGFPRHCYLPDSEKGRKVLKLLLVAWDRRLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DCKTIRIIYSIPPGIQGPEHPNPGKSFSARGFPRHCYLPDSEKGRKVLKLLLVAWDRRLI 400 410 420 430 440 450 560 570 580 590 600 610 pF1KA0 FAIGTSSTTGESDTVIWNEVHHKTEFGSNLTGHGYPDANYLDNVLAELAAQGISEDSTAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FAIGTSSTTGESDTVIWNEVHHKTEFGSNLTGHGYPDANYLDNVLAELAAQGISEDSTAQ 460 470 480 490 500 510 pF1KA0 EKD ::: NP_001 EKD >>XP_011536311 (OMIM: 602582) PREDICTED: E3 ubiquitin-pr (620 aa) initn: 2559 init1: 1130 opt: 1871 Z-score: 1168.2 bits: 226.3 E(85289): 2.5e-58 Smith-Waterman score: 2758; 64.9% identity (84.4% similar) in 610 aa overlap (7-611:25-615) 10 20 30 40 pF1KA0 MLLASAVVVWEWLNEHGRWRPYSPAVSHHIEAVVRAGPRAGG ::::::::::.:::::. .: :::: :.. : : XP_011 MSRPGHGGLMPVNGLGFPPQNVARVVVWEWLNEHSRWRPYTATVCHHIENVLKEDAR--G 10 20 30 40 50 50 60 70 80 90 100 pF1KA0 SVVLGQVDSRLAPYIIDLQSMNQFRQDTGTLRPVRRNYYDPSSAPGKGVVWEWENDNGSW ::::::::..:.:::::::::.::::::::.::::::.::::::::::.:::::::.:.: XP_011 SVVLGQVDAQLVPYIIDLQSMHQFRQDTGTMRPVRRNFYDPSSAPGKGIVWEWENDGGAW 60 70 80 90 100 110 110 120 130 140 150 160 pF1KA0 TPYDMEVGITIQHAYEKQHPWIDLTSIGFSYVIDFNTMGQINRQTQRQRRVRRRLDLIYP : :::.. ::::.::::::::.::.:.:: :.: ::.:.:.::::.:.::.:::::: :: XP_011 TAYDMDICITIQNAYEKQHPWLDLSSLGFCYLIYFNSMSQMNRQTRRRRRLRRRLDLAYP 120 130 140 150 160 170 170 180 190 200 210 220 pF1KA0 MVTGTLPKAQSWPVSPGPATSPPMSPCSCPQCVLVMSVKAAVVNGSTGPLQLPVTRKNMP ...:..::.:::::. :.: .:::: ::.:: :..:: .. . : :.. : XP_011 LTVGSIPKSQSWPVG---ASSG--QPCSCQQCLLVNSTRAA-----SNAI-LASQRRKAP 180 190 200 210 220 230 240 250 260 270 pF1KA0 PPGVVKLPPLPGS--GAKPLDSTGTIRGP-LKTAPSQVIRRQASSMPTGTTMGSPASPPG : . :: ::. :: . ..:. : : .::. . : : :. ::..: : XP_011 PAPPLPPPPPPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAP--PPGAPPRSPGAPGG 230 240 250 260 270 280 280 290 300 310 320 330 pF1KA0 PNSKTGRVALATLNRTNLQRLAIAQSRVLIASGVPTVPVKNLNGSSPVNPALAGITGILM . :. .::: . :: . ...:. : :::..:::::::..::.:::::.::::. XP_011 ARTP-GQ---NNLNRPGPQRTTSVSARASIPPGVPALPVKNLNGTGPVHPALAGMTGILL 290 300 310 320 330 340 340 350 360 370 380 390 pF1KA0 SAAGLPVCLTRPPKLVLHPPPVSKSEIKSIPGVSNTSRKTTKKQAKKGKTPEEVLKKYLQ :::::::::: :: .:::::::::..: .::: .. ::: ::. ::.:.::.:...:.: XP_011 CAAGLPVCLTRAPKPILHPPPVSKSDVKPVPGVPGVCRKTKKKHLKKSKNPEDVVRRYMQ 350 360 370 380 390 400 400 410 420 430 440 450 pF1KA0 KVRHPPDEDCTICMERLTAPSGYKGP--QPTVKPDLVGKLSRCGHVYHIYCLVAMYNNGN ::..:::::::::::::.. :::.: . :.:.:::.:.::::.::. ::::::.::: XP_011 KVKNPPDEDCTICMERLVTASGYEGVLRHKGVRPELVGRLGRCGHMYHLLCLVAMYSNGN 410 420 430 440 450 460 460 470 480 490 500 510 pF1KA0 KDGSLQCPTCKTIYGVKTGTQPPGKMEYHLIPHSLPGHPDCKTIRIIYSIPPGIQGPEHP :::::::::::.::: :::::::::::.::::::::: :: .::::.:.:: :::::::: XP_011 KDGSLQCPTCKAIYGEKTGTQPPGKMEFHLIPHSLPGFPDTQTIRIVYDIPTGIQGPEHP 470 480 490 500 510 520 520 530 540 550 560 570 pF1KA0 NPGKSFSARGFPRHCYLPDSEKGRKVLKLLLVAWDRRLIFAIGTSSTTGESDTVIWNEVH ::::.:.:::::::::::..:::::::.::..::.:::::.::::.::::::::.:::.: XP_011 NPGKKFTARGFPRHCYLPNNEKGRKVLRLLITAWERRLIFTIGTSNTTGESDTVVWNEIH 530 540 550 560 570 580 580 590 600 610 pF1KA0 HKTEFGSNLTGHGYPDANYLDNVLAELAAQGISEDSTAQEKD :::::::::::::::::.:::::::::.:::.:: XP_011 HKTEFGSNLTGHGYPDASYLDNVLAELTAQGVSEAAAKA 590 600 610 620 >>NP_004407 (OMIM: 602582) E3 ubiquitin-protein ligase D (620 aa) initn: 2559 init1: 1130 opt: 1871 Z-score: 1168.2 bits: 226.3 E(85289): 2.5e-58 Smith-Waterman score: 2758; 64.9% identity (84.4% similar) in 610 aa overlap (7-611:25-615) 10 20 30 40 pF1KA0 MLLASAVVVWEWLNEHGRWRPYSPAVSHHIEAVVRAGPRAGG ::::::::::.:::::. .: :::: :.. : : NP_004 MSRPGHGGLMPVNGLGFPPQNVARVVVWEWLNEHSRWRPYTATVCHHIENVLKEDAR--G 10 20 30 40 50 50 60 70 80 90 100 pF1KA0 SVVLGQVDSRLAPYIIDLQSMNQFRQDTGTLRPVRRNYYDPSSAPGKGVVWEWENDNGSW ::::::::..:.:::::::::.::::::::.::::::.::::::::::.:::::::.:.: NP_004 SVVLGQVDAQLVPYIIDLQSMHQFRQDTGTMRPVRRNFYDPSSAPGKGIVWEWENDGGAW 60 70 80 90 100 110 110 120 130 140 150 160 pF1KA0 TPYDMEVGITIQHAYEKQHPWIDLTSIGFSYVIDFNTMGQINRQTQRQRRVRRRLDLIYP : :::.. ::::.::::::::.::.:.:: :.: ::.:.:.::::.:.::.:::::: :: NP_004 TAYDMDICITIQNAYEKQHPWLDLSSLGFCYLIYFNSMSQMNRQTRRRRRLRRRLDLAYP 120 130 140 150 160 170 170 180 190 200 210 220 pF1KA0 MVTGTLPKAQSWPVSPGPATSPPMSPCSCPQCVLVMSVKAAVVNGSTGPLQLPVTRKNMP ...:..::.:::::. :.: .:::: ::.:: :..:: .. . : :.. : NP_004 LTVGSIPKSQSWPVG---ASSG--QPCSCQQCLLVNSTRAA-----SNAI-LASQRRKAP 180 190 200 210 220 230 240 250 260 270 pF1KA0 PPGVVKLPPLPGS--GAKPLDSTGTIRGP-LKTAPSQVIRRQASSMPTGTTMGSPASPPG : . :: ::. :: . ..:. : : .::. . : : :. ::..: : NP_004 PAPPLPPPPPPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAP--PPGAPPRSPGAPGG 230 240 250 260 270 280 280 290 300 310 320 330 pF1KA0 PNSKTGRVALATLNRTNLQRLAIAQSRVLIASGVPTVPVKNLNGSSPVNPALAGITGILM . :. .::: . :: . ...:. : :::..:::::::..::.:::::.::::. NP_004 ARTP-GQ---NNLNRPGPQRTTSVSARASIPPGVPALPVKNLNGTGPVHPALAGMTGILL 290 300 310 320 330 340 340 350 360 370 380 390 pF1KA0 SAAGLPVCLTRPPKLVLHPPPVSKSEIKSIPGVSNTSRKTTKKQAKKGKTPEEVLKKYLQ :::::::::: :: .:::::::::..: .::: .. ::: ::. ::.:.::.:...:.: NP_004 CAAGLPVCLTRAPKPILHPPPVSKSDVKPVPGVPGVCRKTKKKHLKKSKNPEDVVRRYMQ 350 360 370 380 390 400 400 410 420 430 440 450 pF1KA0 KVRHPPDEDCTICMERLTAPSGYKGP--QPTVKPDLVGKLSRCGHVYHIYCLVAMYNNGN ::..:::::::::::::.. :::.: . :.:.:::.:.::::.::. ::::::.::: NP_004 KVKNPPDEDCTICMERLVTASGYEGVLRHKGVRPELVGRLGRCGHMYHLLCLVAMYSNGN 410 420 430 440 450 460 460 470 480 490 500 510 pF1KA0 KDGSLQCPTCKTIYGVKTGTQPPGKMEYHLIPHSLPGHPDCKTIRIIYSIPPGIQGPEHP :::::::::::.::: :::::::::::.::::::::: :: .::::.:.:: :::::::: NP_004 KDGSLQCPTCKAIYGEKTGTQPPGKMEFHLIPHSLPGFPDTQTIRIVYDIPTGIQGPEHP 470 480 490 500 510 520 520 530 540 550 560 570 pF1KA0 NPGKSFSARGFPRHCYLPDSEKGRKVLKLLLVAWDRRLIFAIGTSSTTGESDTVIWNEVH ::::.:.:::::::::::..:::::::.::..::.:::::.::::.::::::::.:::.: NP_004 NPGKKFTARGFPRHCYLPNNEKGRKVLRLLITAWERRLIFTIGTSNTTGESDTVVWNEIH 530 540 550 560 570 580 580 590 600 610 pF1KA0 HKTEFGSNLTGHGYPDANYLDNVLAELAAQGISEDSTAQEKD :::::::::::::::::.:::::::::.:::.:: NP_004 HKTEFGSNLTGHGYPDASYLDNVLAELTAQGVSEAAAKA 590 600 610 620 >>XP_016867213 (OMIM: 613141) PREDICTED: probable E3 ubi (622 aa) initn: 1763 init1: 984 opt: 1316 Z-score: 827.0 bits: 163.2 E(85289): 2.5e-39 Smith-Waterman score: 1763; 46.9% identity (67.1% similar) in 635 aa overlap (5-617:17-622) 10 20 30 40 pF1KA0 MLLASAVVVWEWLNEHGRWRPYSPAVSHHIEA--VVRAGPRAG-GSVV .::.:::: . : :.::: .: :: : . : : : ::.. XP_016 MAMAPSPSLVQVYTSPAAVAVWEWQDGLGTWHPYSATVCSFIEQQFVQQKGQRFGLGSLA 10 20 30 40 50 60 50 60 70 80 90 100 pF1KA0 ----LGQVDSRLAPYIIDLQSMNQFRQDTGTLRPVRRNYYDPSSAPGKGVVWEWENDNGS :::.: :::::::: : .::::::::.: :::. . ::::.:::::: .:.:: XP_016 HSIPLGQADPSLAPYIIDLPSWTQFRQDTGTMRAVRRHLFPQHSAPGRGVVWEWLSDDGS 70 80 90 100 110 120 110 120 130 140 150 160 pF1KA0 WTPYDMEVGITIQHAYEKQHPWIDLTSIGFSYVIDFNTMGQINRQTQRQRRVRRRLDLIY :: :. : ... . . .::. .:..:.....: : :. .. : :::. : XP_016 WTAYEASVCDYLEQQVARGNQLVDLAPLGYNYTVNYTTHTQTNKTSSFCRSVRRQAGPPY 130 140 150 160 170 180 170 180 190 200 210 220 pF1KA0 PMVTGTLPKAQSWPVSPGPATSPPMSPCSCPQCVLVMSVKAAVVNGS-TGPLQLPVTRKN :..: : : : : ::: ::. .:: :::.. :.. XP_016 PVTTIIAP-----PGHTGVA-------CSCHQCL----------SGSRTGPVS-GRYRHS 190 200 210 230 240 250 260 270 280 pF1KA0 MPPPGVVKLPPLPGSGAKPLDSTGTIRGPLKTAPSQVIRRQASSMPTGTTMGSPASPPGP : . .: : . . .: .: . :: :.: . : .. : :.::. XP_016 MTNLPAYPVPQHPPHRTASVFGTHQAFAPYNK-PSLSGARSAPRLNTTNAWG--AAPPSL 220 230 240 250 260 270 290 300 310 320 pF1KA0 NSKT-GRVALATLNRTNLQRLAIAQSRVL--IASG-------VP-TVPVKNLNGSSPVNP .:. : .:. :. .: . ... : . :: :: :::.. . : :. XP_016 GSQPLYRSSLSHLGPQHLPPGSSTSGAVSASLPSGPSSSPGSVPATVPMQ-MPKPSRVQQ 280 290 300 310 320 330 330 340 350 360 370 380 pF1KA0 ALAGITGILMSAAGLPVCLTRPPKLVLHPPPVSKSEIKSIPGVSNTSRKTTKKQAKKGKT ::::.:..:::: ::::::.: :. . ::.:. :: .:. . ..: . : . XP_016 ALAGMTSVLMSAIGLPVCLSRAPQPT--SPPASRLASKSHGSVKRLRKMSVKGATPKPEP 340 350 360 370 380 390 390 400 410 420 430 440 pF1KA0 -PEEVLKKYLQKVRHPPDEDCTICMERLTAPSGYKG--PQPTVKPDLVGKLSRCGHVYHI ::.:.:.: .... :::::: ::::.:.. :::. . .. ::.:..:.:..:. XP_016 EPEQVIKNYTEELKVPPDEDCIICMEKLSTASGYSDVTDSKAIGSLAVGHLTKCSHAFHL 400 410 420 430 440 450 450 460 470 480 490 500 pF1KA0 YCLVAMYNNGNKDGSLQCPTCKTIYGVKTGTQPPGKMEYHLIPHSLPGHPDCKTIRIIYS ::.::: :::::::::::.:::::: :::::: :::: . ::::: :: :: :.:: XP_016 LCLLAMYCNGNKDGSLQCPSCKTIYGEKTGTQPQGKMEVLRFQMSLPGHEDCGTILIVYS 460 470 480 490 500 510 510 520 530 540 550 560 pF1KA0 IPPGIQGPEHPNPGKSFSARGFPRHCYLPDSEKGRKVLKLLLVAWDRRLIFAIGTSSTTG :: :::::::::::: :.::::::.:::::. .:::::.:: ::: :::::..::::::: XP_016 IPHGIQGPEHPNPGKPFTARGFPRQCYLPDNAQGRKVLELLKVAWKRRLIFTVGTSSTTG 520 530 540 550 560 570 570 580 590 600 610 pF1KA0 ESDTVIWNEVHHKTEFGSNLTGHGYPDANYLDNVLAELAAQGISEDSTAQEKD :.:::.:::.:::::. :.::::::: :::.::::::::::..:: :. XP_016 ETDTVVWNEIHHKTEMDRNITGHGYPDPNYLQNVLAELAAQGVTEDCLEQQ 580 590 600 610 620 >>XP_005250188 (OMIM: 613141) PREDICTED: probable E3 ubi (622 aa) initn: 1763 init1: 984 opt: 1316 Z-score: 827.0 bits: 163.2 E(85289): 2.5e-39 Smith-Waterman score: 1763; 46.9% identity (67.1% similar) in 635 aa overlap (5-617:17-622) 10 20 30 40 pF1KA0 MLLASAVVVWEWLNEHGRWRPYSPAVSHHIEA--VVRAGPRAG-GSVV .::.:::: . : :.::: .: :: : . : : : ::.. XP_005 MAMAPSPSLVQVYTSPAAVAVWEWQDGLGTWHPYSATVCSFIEQQFVQQKGQRFGLGSLA 10 20 30 40 50 60 50 60 70 80 90 100 pF1KA0 ----LGQVDSRLAPYIIDLQSMNQFRQDTGTLRPVRRNYYDPSSAPGKGVVWEWENDNGS :::.: :::::::: : .::::::::.: :::. . ::::.:::::: .:.:: XP_005 HSIPLGQADPSLAPYIIDLPSWTQFRQDTGTMRAVRRHLFPQHSAPGRGVVWEWLSDDGS 70 80 90 100 110 120 110 120 130 140 150 160 pF1KA0 WTPYDMEVGITIQHAYEKQHPWIDLTSIGFSYVIDFNTMGQINRQTQRQRRVRRRLDLIY :: :. : ... . . .::. .:..:.....: : :. .. : :::. : XP_005 WTAYEASVCDYLEQQVARGNQLVDLAPLGYNYTVNYTTHTQTNKTSSFCRSVRRQAGPPY 130 140 150 160 170 180 170 180 190 200 210 220 pF1KA0 PMVTGTLPKAQSWPVSPGPATSPPMSPCSCPQCVLVMSVKAAVVNGS-TGPLQLPVTRKN :..: : : : : ::: ::. .:: :::.. :.. XP_005 PVTTIIAP-----PGHTGVA-------CSCHQCL----------SGSRTGPVS-GRYRHS 190 200 210 230 240 250 260 270 280 pF1KA0 MPPPGVVKLPPLPGSGAKPLDSTGTIRGPLKTAPSQVIRRQASSMPTGTTMGSPASPPGP : . .: : . . .: .: . :: :.: . : .. : :.::. XP_005 MTNLPAYPVPQHPPHRTASVFGTHQAFAPYNK-PSLSGARSAPRLNTTNAWG--AAPPSL 220 230 240 250 260 270 290 300 310 320 pF1KA0 NSKT-GRVALATLNRTNLQRLAIAQSRVL--IASG-------VP-TVPVKNLNGSSPVNP .:. : .:. :. .: . ... : . :: :: :::.. . : :. XP_005 GSQPLYRSSLSHLGPQHLPPGSSTSGAVSASLPSGPSSSPGSVPATVPMQ-MPKPSRVQQ 280 290 300 310 320 330 330 340 350 360 370 380 pF1KA0 ALAGITGILMSAAGLPVCLTRPPKLVLHPPPVSKSEIKSIPGVSNTSRKTTKKQAKKGKT ::::.:..:::: ::::::.: :. . ::.:. :: .:. . ..: . : . XP_005 ALAGMTSVLMSAIGLPVCLSRAPQPT--SPPASRLASKSHGSVKRLRKMSVKGATPKPEP 340 350 360 370 380 390 390 400 410 420 430 440 pF1KA0 -PEEVLKKYLQKVRHPPDEDCTICMERLTAPSGYKG--PQPTVKPDLVGKLSRCGHVYHI ::.:.:.: .... :::::: ::::.:.. :::. . .. ::.:..:.:..:. XP_005 EPEQVIKNYTEELKVPPDEDCIICMEKLSTASGYSDVTDSKAIGSLAVGHLTKCSHAFHL 400 410 420 430 440 450 450 460 470 480 490 500 pF1KA0 YCLVAMYNNGNKDGSLQCPTCKTIYGVKTGTQPPGKMEYHLIPHSLPGHPDCKTIRIIYS ::.::: :::::::::::.:::::: :::::: :::: . ::::: :: :: :.:: XP_005 LCLLAMYCNGNKDGSLQCPSCKTIYGEKTGTQPQGKMEVLRFQMSLPGHEDCGTILIVYS 460 470 480 490 500 510 510 520 530 540 550 560 pF1KA0 IPPGIQGPEHPNPGKSFSARGFPRHCYLPDSEKGRKVLKLLLVAWDRRLIFAIGTSSTTG :: :::::::::::: :.::::::.:::::. .:::::.:: ::: :::::..::::::: XP_005 IPHGIQGPEHPNPGKPFTARGFPRQCYLPDNAQGRKVLELLKVAWKRRLIFTVGTSSTTG 520 530 540 550 560 570 570 580 590 600 610 pF1KA0 ESDTVIWNEVHHKTEFGSNLTGHGYPDANYLDNVLAELAAQGISEDSTAQEKD :.:::.:::.:::::. :.::::::: :::.::::::::::..:: :. XP_005 ETDTVVWNEIHHKTEMDRNITGHGYPDPNYLQNVLAELAAQGVTEDCLEQQ 580 590 600 610 620 >>XP_011514076 (OMIM: 613141) PREDICTED: probable E3 ubi (622 aa) initn: 1763 init1: 984 opt: 1316 Z-score: 827.0 bits: 163.2 E(85289): 2.5e-39 Smith-Waterman score: 1763; 46.9% identity (67.1% similar) in 635 aa overlap (5-617:17-622) 10 20 30 40 pF1KA0 MLLASAVVVWEWLNEHGRWRPYSPAVSHHIEA--VVRAGPRAG-GSVV .::.:::: . : :.::: .: :: : . : : : ::.. XP_011 MAMAPSPSLVQVYTSPAAVAVWEWQDGLGTWHPYSATVCSFIEQQFVQQKGQRFGLGSLA 10 20 30 40 50 60 50 60 70 80 90 100 pF1KA0 ----LGQVDSRLAPYIIDLQSMNQFRQDTGTLRPVRRNYYDPSSAPGKGVVWEWENDNGS :::.: :::::::: : .::::::::.: :::. . ::::.:::::: .:.:: XP_011 HSIPLGQADPSLAPYIIDLPSWTQFRQDTGTMRAVRRHLFPQHSAPGRGVVWEWLSDDGS 70 80 90 100 110 120 110 120 130 140 150 160 pF1KA0 WTPYDMEVGITIQHAYEKQHPWIDLTSIGFSYVIDFNTMGQINRQTQRQRRVRRRLDLIY :: :. : ... . . .::. .:..:.....: : :. .. : :::. : XP_011 WTAYEASVCDYLEQQVARGNQLVDLAPLGYNYTVNYTTHTQTNKTSSFCRSVRRQAGPPY 130 140 150 160 170 180 170 180 190 200 210 220 pF1KA0 PMVTGTLPKAQSWPVSPGPATSPPMSPCSCPQCVLVMSVKAAVVNGS-TGPLQLPVTRKN :..: : : : : ::: ::. .:: :::.. :.. XP_011 PVTTIIAP-----PGHTGVA-------CSCHQCL----------SGSRTGPVS-GRYRHS 190 200 210 230 240 250 260 270 280 pF1KA0 MPPPGVVKLPPLPGSGAKPLDSTGTIRGPLKTAPSQVIRRQASSMPTGTTMGSPASPPGP : . .: : . . .: .: . :: :.: . : .. : :.::. XP_011 MTNLPAYPVPQHPPHRTASVFGTHQAFAPYNK-PSLSGARSAPRLNTTNAWG--AAPPSL 220 230 240 250 260 270 290 300 310 320 pF1KA0 NSKT-GRVALATLNRTNLQRLAIAQSRVL--IASG-------VP-TVPVKNLNGSSPVNP .:. : .:. :. .: . ... : . :: :: :::.. . : :. XP_011 GSQPLYRSSLSHLGPQHLPPGSSTSGAVSASLPSGPSSSPGSVPATVPMQ-MPKPSRVQQ 280 290 300 310 320 330 330 340 350 360 370 380 pF1KA0 ALAGITGILMSAAGLPVCLTRPPKLVLHPPPVSKSEIKSIPGVSNTSRKTTKKQAKKGKT ::::.:..:::: ::::::.: :. . ::.:. :: .:. . ..: . : . XP_011 ALAGMTSVLMSAIGLPVCLSRAPQPT--SPPASRLASKSHGSVKRLRKMSVKGATPKPEP 340 350 360 370 380 390 390 400 410 420 430 440 pF1KA0 -PEEVLKKYLQKVRHPPDEDCTICMERLTAPSGYKG--PQPTVKPDLVGKLSRCGHVYHI ::.:.:.: .... :::::: ::::.:.. :::. . .. ::.:..:.:..:. XP_011 EPEQVIKNYTEELKVPPDEDCIICMEKLSTASGYSDVTDSKAIGSLAVGHLTKCSHAFHL 400 410 420 430 440 450 450 460 470 480 490 500 pF1KA0 YCLVAMYNNGNKDGSLQCPTCKTIYGVKTGTQPPGKMEYHLIPHSLPGHPDCKTIRIIYS ::.::: :::::::::::.:::::: :::::: :::: . ::::: :: :: :.:: XP_011 LCLLAMYCNGNKDGSLQCPSCKTIYGEKTGTQPQGKMEVLRFQMSLPGHEDCGTILIVYS 460 470 480 490 500 510 510 520 530 540 550 560 pF1KA0 IPPGIQGPEHPNPGKSFSARGFPRHCYLPDSEKGRKVLKLLLVAWDRRLIFAIGTSSTTG :: :::::::::::: :.::::::.:::::. .:::::.:: ::: :::::..::::::: XP_011 IPHGIQGPEHPNPGKPFTARGFPRQCYLPDNAQGRKVLELLKVAWKRRLIFTVGTSSTTG 520 530 540 550 560 570 570 580 590 600 610 pF1KA0 ESDTVIWNEVHHKTEFGSNLTGHGYPDANYLDNVLAELAAQGISEDSTAQEKD :.:::.:::.:::::. :.::::::: :::.::::::::::..:: :. XP_011 ETDTVVWNEIHHKTEMDRNITGHGYPDPNYLQNVLAELAAQGVTEDCLEQQ 580 590 600 610 620 >>XP_016867214 (OMIM: 613141) PREDICTED: probable E3 ubi (622 aa) initn: 1763 init1: 984 opt: 1316 Z-score: 827.0 bits: 163.2 E(85289): 2.5e-39 Smith-Waterman score: 1763; 46.9% identity (67.1% similar) in 635 aa overlap (5-617:17-622) 10 20 30 40 pF1KA0 MLLASAVVVWEWLNEHGRWRPYSPAVSHHIEA--VVRAGPRAG-GSVV .::.:::: . : :.::: .: :: : . : : : ::.. XP_016 MAMAPSPSLVQVYTSPAAVAVWEWQDGLGTWHPYSATVCSFIEQQFVQQKGQRFGLGSLA 10 20 30 40 50 60 50 60 70 80 90 100 pF1KA0 ----LGQVDSRLAPYIIDLQSMNQFRQDTGTLRPVRRNYYDPSSAPGKGVVWEWENDNGS :::.: :::::::: : .::::::::.: :::. . ::::.:::::: .:.:: XP_016 HSIPLGQADPSLAPYIIDLPSWTQFRQDTGTMRAVRRHLFPQHSAPGRGVVWEWLSDDGS 70 80 90 100 110 120 110 120 130 140 150 160 pF1KA0 WTPYDMEVGITIQHAYEKQHPWIDLTSIGFSYVIDFNTMGQINRQTQRQRRVRRRLDLIY :: :. : ... . . .::. .:..:.....: : :. .. : :::. : XP_016 WTAYEASVCDYLEQQVARGNQLVDLAPLGYNYTVNYTTHTQTNKTSSFCRSVRRQAGPPY 130 140 150 160 170 180 170 180 190 200 210 220 pF1KA0 PMVTGTLPKAQSWPVSPGPATSPPMSPCSCPQCVLVMSVKAAVVNGS-TGPLQLPVTRKN :..: : : : : ::: ::. .:: :::.. :.. XP_016 PVTTIIAP-----PGHTGVA-------CSCHQCL----------SGSRTGPVS-GRYRHS 190 200 210 230 240 250 260 270 280 pF1KA0 MPPPGVVKLPPLPGSGAKPLDSTGTIRGPLKTAPSQVIRRQASSMPTGTTMGSPASPPGP : . .: : . . .: .: . :: :.: . : .. : :.::. XP_016 MTNLPAYPVPQHPPHRTASVFGTHQAFAPYNK-PSLSGARSAPRLNTTNAWG--AAPPSL 220 230 240 250 260 270 290 300 310 320 pF1KA0 NSKT-GRVALATLNRTNLQRLAIAQSRVL--IASG-------VP-TVPVKNLNGSSPVNP .:. : .:. :. .: . ... : . :: :: :::.. . : :. XP_016 GSQPLYRSSLSHLGPQHLPPGSSTSGAVSASLPSGPSSSPGSVPATVPMQ-MPKPSRVQQ 280 290 300 310 320 330 330 340 350 360 370 380 pF1KA0 ALAGITGILMSAAGLPVCLTRPPKLVLHPPPVSKSEIKSIPGVSNTSRKTTKKQAKKGKT ::::.:..:::: ::::::.: :. . ::.:. :: .:. . ..: . : . XP_016 ALAGMTSVLMSAIGLPVCLSRAPQPT--SPPASRLASKSHGSVKRLRKMSVKGATPKPEP 340 350 360 370 380 390 390 400 410 420 430 440 pF1KA0 -PEEVLKKYLQKVRHPPDEDCTICMERLTAPSGYKG--PQPTVKPDLVGKLSRCGHVYHI ::.:.:.: .... :::::: ::::.:.. :::. . .. ::.:..:.:..:. XP_016 EPEQVIKNYTEELKVPPDEDCIICMEKLSTASGYSDVTDSKAIGSLAVGHLTKCSHAFHL 400 410 420 430 440 450 450 460 470 480 490 500 pF1KA0 YCLVAMYNNGNKDGSLQCPTCKTIYGVKTGTQPPGKMEYHLIPHSLPGHPDCKTIRIIYS ::.::: :::::::::::.:::::: :::::: :::: . ::::: :: :: :.:: XP_016 LCLLAMYCNGNKDGSLQCPSCKTIYGEKTGTQPQGKMEVLRFQMSLPGHEDCGTILIVYS 460 470 480 490 500 510 510 520 530 540 550 560 pF1KA0 IPPGIQGPEHPNPGKSFSARGFPRHCYLPDSEKGRKVLKLLLVAWDRRLIFAIGTSSTTG :: :::::::::::: :.::::::.:::::. .:::::.:: ::: :::::..::::::: XP_016 IPHGIQGPEHPNPGKPFTARGFPRQCYLPDNAQGRKVLELLKVAWKRRLIFTVGTSSTTG 520 530 540 550 560 570 570 580 590 600 610 pF1KA0 ESDTVIWNEVHHKTEFGSNLTGHGYPDANYLDNVLAELAAQGISEDSTAQEKD :.:::.:::.:::::. :.::::::: :::.::::::::::..:: :. XP_016 ETDTVVWNEIHHKTEMDRNITGHGYPDPNYLQNVLAELAAQGVTEDCLEQQ 580 590 600 610 620 >>XP_016867212 (OMIM: 613141) PREDICTED: probable E3 ubi (622 aa) initn: 1763 init1: 984 opt: 1316 Z-score: 827.0 bits: 163.2 E(85289): 2.5e-39 Smith-Waterman score: 1763; 46.9% identity (67.1% similar) in 635 aa overlap (5-617:17-622) 10 20 30 40 pF1KA0 MLLASAVVVWEWLNEHGRWRPYSPAVSHHIEA--VVRAGPRAG-GSVV .::.:::: . : :.::: .: :: : . : : : ::.. XP_016 MAMAPSPSLVQVYTSPAAVAVWEWQDGLGTWHPYSATVCSFIEQQFVQQKGQRFGLGSLA 10 20 30 40 50 60 50 60 70 80 90 100 pF1KA0 ----LGQVDSRLAPYIIDLQSMNQFRQDTGTLRPVRRNYYDPSSAPGKGVVWEWENDNGS :::.: :::::::: : .::::::::.: :::. . ::::.:::::: .:.:: XP_016 HSIPLGQADPSLAPYIIDLPSWTQFRQDTGTMRAVRRHLFPQHSAPGRGVVWEWLSDDGS 70 80 90 100 110 120 110 120 130 140 150 160 pF1KA0 WTPYDMEVGITIQHAYEKQHPWIDLTSIGFSYVIDFNTMGQINRQTQRQRRVRRRLDLIY :: :. : ... . . .::. .:..:.....: : :. .. : :::. : XP_016 WTAYEASVCDYLEQQVARGNQLVDLAPLGYNYTVNYTTHTQTNKTSSFCRSVRRQAGPPY 130 140 150 160 170 180 170 180 190 200 210 220 pF1KA0 PMVTGTLPKAQSWPVSPGPATSPPMSPCSCPQCVLVMSVKAAVVNGS-TGPLQLPVTRKN :..: : : : : ::: ::. .:: :::.. :.. XP_016 PVTTIIAP-----PGHTGVA-------CSCHQCL----------SGSRTGPVS-GRYRHS 190 200 210 230 240 250 260 270 280 pF1KA0 MPPPGVVKLPPLPGSGAKPLDSTGTIRGPLKTAPSQVIRRQASSMPTGTTMGSPASPPGP : . .: : . . .: .: . :: :.: . : .. : :.::. XP_016 MTNLPAYPVPQHPPHRTASVFGTHQAFAPYNK-PSLSGARSAPRLNTTNAWG--AAPPSL 220 230 240 250 260 270 290 300 310 320 pF1KA0 NSKT-GRVALATLNRTNLQRLAIAQSRVL--IASG-------VP-TVPVKNLNGSSPVNP .:. : .:. :. .: . ... : . :: :: :::.. . : :. XP_016 GSQPLYRSSLSHLGPQHLPPGSSTSGAVSASLPSGPSSSPGSVPATVPMQ-MPKPSRVQQ 280 290 300 310 320 330 330 340 350 360 370 380 pF1KA0 ALAGITGILMSAAGLPVCLTRPPKLVLHPPPVSKSEIKSIPGVSNTSRKTTKKQAKKGKT ::::.:..:::: ::::::.: :. . ::.:. :: .:. . ..: . : . XP_016 ALAGMTSVLMSAIGLPVCLSRAPQPT--SPPASRLASKSHGSVKRLRKMSVKGATPKPEP 340 350 360 370 380 390 390 400 410 420 430 440 pF1KA0 -PEEVLKKYLQKVRHPPDEDCTICMERLTAPSGYKG--PQPTVKPDLVGKLSRCGHVYHI ::.:.:.: .... :::::: ::::.:.. :::. . .. ::.:..:.:..:. XP_016 EPEQVIKNYTEELKVPPDEDCIICMEKLSTASGYSDVTDSKAIGSLAVGHLTKCSHAFHL 400 410 420 430 440 450 450 460 470 480 490 500 pF1KA0 YCLVAMYNNGNKDGSLQCPTCKTIYGVKTGTQPPGKMEYHLIPHSLPGHPDCKTIRIIYS ::.::: :::::::::::.:::::: :::::: :::: . ::::: :: :: :.:: XP_016 LCLLAMYCNGNKDGSLQCPSCKTIYGEKTGTQPQGKMEVLRFQMSLPGHEDCGTILIVYS 460 470 480 490 500 510 510 520 530 540 550 560 pF1KA0 IPPGIQGPEHPNPGKSFSARGFPRHCYLPDSEKGRKVLKLLLVAWDRRLIFAIGTSSTTG :: :::::::::::: :.::::::.:::::. .:::::.:: ::: :::::..::::::: XP_016 IPHGIQGPEHPNPGKPFTARGFPRQCYLPDNAQGRKVLELLKVAWKRRLIFTVGTSSTTG 520 530 540 550 560 570 570 580 590 600 610 pF1KA0 ESDTVIWNEVHHKTEFGSNLTGHGYPDANYLDNVLAELAAQGISEDSTAQEKD :.:::.:::.:::::. :.::::::: :::.::::::::::..:: :. XP_016 ETDTVVWNEIHHKTEMDRNITGHGYPDPNYLQNVLAELAAQGVTEDCLEQQ 580 590 600 610 620 619 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 20:03:35 2016 done: Wed Nov 2 20:03:36 2016 Total Scan time: 11.060 Total Display time: 0.080 Function used was FASTA [36.3.4 Apr, 2011]