FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0946, 632 aa 1>>>pF1KA0946 632 - 632 aa - 632 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.7821+/-0.00149; mu= 11.5813+/- 0.087 mean_var=149.4921+/-31.848, 0's: 0 Z-trim(103.3): 237 B-trim: 135 in 1/49 Lambda= 0.104898 statistics sampled from 7071 (7363) to 7071 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.574), E-opt: 0.2 (0.226), width: 16 Scan time: 2.320 The best scores are: opt bits E(32554) CCDS44946.1 ZDHHC17 gene_id:23390|Hs108|chr12 ( 632) 4444 685.7 4.8e-197 CCDS44550.1 ZDHHC13 gene_id:54503|Hs108|chr11 ( 622) 2096 330.4 4.4e-90 CCDS44551.1 ZDHHC13 gene_id:54503|Hs108|chr11 ( 492) 1581 252.4 1.1e-66 >>CCDS44946.1 ZDHHC17 gene_id:23390|Hs108|chr12 (632 aa) initn: 4444 init1: 4444 opt: 4444 Z-score: 3651.0 bits: 685.7 E(32554): 4.8e-197 Smith-Waterman score: 4444; 100.0% identity (100.0% similar) in 632 aa overlap (1-632:1-632) 10 20 30 40 50 60 pF1KA0 MQREEGFNTKMADGPDEYDTEAGCVPLLHPEEIKPQSHYNHGYGEPLGRKTHIDDYSTWD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 MQREEGFNTKMADGPDEYDTEAGCVPLLHPEEIKPQSHYNHGYGEPLGRKTHIDDYSTWD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 IVKATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 IVKATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 GDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 GDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 QDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 QDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 ISLLLEAGANVDAQNIKGESALDLAKQRKNVWMINHLQEARQAKGYDNPSFLRKLKADKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 ISLLLEAGANVDAQNIKGESALDLAKQRKNVWMINHLQEARQAKGYDNPSFLRKLKADKE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 FRQKVMLGTPFLVIWLVGFIADLNIDSWLIKGLMYGGVWATVQFLSKSFFDHSMHSALPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 FRQKVMLGTPFLVIWLVGFIADLNIDSWLIKGLMYGGVWATVQFLSKSFFDHSMHSALPL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 GIYLATKFWMYVTWFFWFWNDLNFLFIHLPFLANSVALFYNFGKSWKSDPGIIKATEEQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 GIYLATKFWMYVTWFFWFWNDLNFLFIHLPFLANSVALFYNFGKSWKSDPGIIKATEEQK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 KKTIVELAETGSLDLSIFCSTCLIRKPVRSKHCGVCNRCIAKFDHHCPWVGNCVGAGNHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 KKTIVELAETGSLDLSIFCSTCLIRKPVRSKHCGVCNRCIAKFDHHCPWVGNCVGAGNHR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 YFMGYLFFLLFMICWMIYGCISYWGLHCETTYTKDGFWTYITQIATCSPWMFWMFLNSVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 YFMGYLFFLLFMICWMIYGCISYWGLHCETTYTKDGFWTYITQIATCSPWMFWMFLNSVF 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 HFMWVAVLLMCQMYQISCLGITTNERMNARRYKHFKVTTTSIESPFNHGCVRNIIDFFEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 HFMWVAVLLMCQMYQISCLGITTNERMNARRYKHFKVTTTSIESPFNHGCVRNIIDFFEF 550 560 570 580 590 600 610 620 630 pF1KA0 RCCGLFRPVIVDWTRQYTIEYDQISGSGYQLV :::::::::::::::::::::::::::::::: CCDS44 RCCGLFRPVIVDWTRQYTIEYDQISGSGYQLV 610 620 630 >>CCDS44550.1 ZDHHC13 gene_id:54503|Hs108|chr11 (622 aa) initn: 2070 init1: 1025 opt: 2096 Z-score: 1730.7 bits: 330.4 E(32554): 4.4e-90 Smith-Waterman score: 2096; 51.3% identity (77.9% similar) in 571 aa overlap (53-621:45-611) 30 40 50 60 70 80 pF1KA0 GCVPLLHPEEIKPQSHYNHGYGEPLGRKTHIDDYSTWDIVKATQYGIYERCRELVEAGYD :.: :. ::::::::::.:::.:::::::: CCDS44 HGPHPPGFGRYGICAHENKELANAREALPLIEDSSNCDIVKATQYGIFERCKELVEAGYD 20 30 40 50 60 70 90 100 110 120 130 140 pF1KA0 VRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQ :::::::::.::::::::::.::::.::::::.:::::::::::::::: ::::: ::. CCDS44 VRQPDKENVSLLHWAAINNRLDLVKFYISKGAVVDQLGGDLNSTPLHWAIRQGHLPMVIL 80 90 100 110 120 130 150 160 170 180 190 200 pF1KA0 LMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTH :...::::.:::::: : ::::. : : :.::::.:::.:.: : ::.:::: .:... CCDS44 LLQHGADPTLIDGEGFSSIHLAVLFQHMPIIAYLISKGQSVNMTDVNGQTPLMLSAHKVI 140 150 160 170 180 190 210 220 230 240 250 260 pF1KA0 SVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLEAGANVDAQNIKGESAL . .:: .:: :: :.:. :: :.:: ::::: :::..... :::::...: ::.:::. : CCDS44 GPEPTGFLLKFNPSLNVVDKIHQNTPLHWAVAAGNVNAVDKLLEAGSSLDIQNVKGETPL 200 210 220 230 240 250 270 280 290 300 310 320 pF1KA0 DLAKQRKNVWMINHLQEARQAKGYDNPSFLRKLKADKEFRQKVMLGTPFLVIWLVGFIAD :.: : :: .:. :. . .. .. . : :. . : ..: ...: .:.: : CCDS44 DMALQNKNQLIIHMLKTEAKMRANQKFRLWRWLQKCELF---LLLMLSVITMWAIGYILD 260 270 280 290 300 310 330 340 350 360 370 380 pF1KA0 LNIDSWLIKGLMYGGVWATVQFLSKSFFDHSMHSALPLGIYLATKFWMYVTWFFWFWNDL .: ::::.:: . .. .... . . .. :: .. :.. ::...:::. :. :: CCDS44 FNSDSWLLKGCLLVTLFFLTSLFPRFLVGYKNLVYLPTAFLLSSVFWIFMTWFILFFPDL 320 330 340 350 360 370 390 400 410 420 430 440 pF1KA0 NFLFIHLPFLANSVALFYNFGKSWKSDPGIIKATEEQKKKTIVELAETGSLDLSIFCSTC ... :. . ::..: : :.: .:::. ::.::.:: .:. ::::::::. ::..: CCDS44 AGAPFYFSFIFSIVAFLYFFYKTWATDPGFTKASEEEKKVNIITLAETGSLDFRTFCTSC 380 390 400 410 420 430 450 460 470 480 490 500 pF1KA0 LIRKPVRSKHCGVCNRCIAKFDHHCPWVGNCVGAGNHRYFMGYLFFLLFMIC-WMIYGCI :::::.:: :: ::: :.:..:.:: :.: :.: :::.:.. .:::: :.: :.::: . CCDS44 LIRKPLRSLHCHVCNCCVARYDQHCLWTGRCIGFGNHHYYIFFLFFLS-MVCGWIIYGSF 440 450 460 470 480 490 510 520 530 540 550 560 pF1KA0 SYWGLHCETTYTKDGFWTYITQIATCSPWMFWMFLNSVFHFMWVAVLLMCQMYQISCLGI : . :: ::. .::.:::..::..::::...... ..::: : . ::. :..::. ::. CCDS44 IYLSSHCATTFKEDGLWTYLNQIVACSPWVLYILMLATFHFSWSTFLLLNQLFQIAFLGL 500 510 520 530 540 550 570 580 590 600 610 620 pF1KA0 TTNERMNARRY-KHFKVTTTSIESPFNHGCVRNIIDFFEFRCCGLFRPVIVDWTRQYTIE :..::.. .. ::.: : . ..:.: : ..:. :::. : :: .: .:::: :::. CCDS44 TSHERISLQKQSKHMKQTLSLRKTPYNLGFMQNLADFFQCGCFGLVKPCVVDWTSQYTMV 560 570 580 590 600 610 630 pF1KA0 YDQISGSGYQLV . CCDS44 FHPAREKVLRSV 620 >>CCDS44551.1 ZDHHC13 gene_id:54503|Hs108|chr11 (492 aa) initn: 1568 init1: 861 opt: 1581 Z-score: 1310.8 bits: 252.4 E(32554): 1.1e-66 Smith-Waterman score: 1581; 45.2% identity (74.8% similar) in 485 aa overlap (139-621:1-481) 110 120 130 140 150 160 pF1KA0 YISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFG ::. :...::::.:::::: : ::::. : CCDS44 MVILLLQHGADPTLIDGEGFSSIHLAVLFQ 10 20 30 170 180 190 200 210 220 pF1KA0 HTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTA : :.::::.:::.:.: : ::.:::: .:... . .:: .:: :: :.:. :: :.:: CCDS44 HMPIIAYLISKGQSVNMTDVNGQTPLMLSAHKVIGPEPTGFLLKFNPSLNVVDKIHQNTP 40 50 60 70 80 90 230 240 250 260 270 280 pF1KA0 LHWAVLAGNTTVISLLLEAGANVDAQNIKGESALDLAKQRKNVWMINHLQEARQAKGYDN ::::: :::..... :::::...: ::.:::. ::.: : :: .:. :. . .. .. CCDS44 LHWAVAAGNVNAVDKLLEAGSSLDIQNVKGETPLDMALQNKNQLIIHMLKTEAKMRANQK 100 110 120 130 140 150 290 300 310 320 330 340 pF1KA0 PSFLRKLKADKEFRQKVMLGTPFLVIWLVGFIADLNIDSWLIKGLMYGGVWATVQFLSKS . : :. . : ..: ...: .:.: :.: ::::.:: . .. .... . CCDS44 FRLWRWLQKCELF---LLLMLSVITMWAIGYILDFNSDSWLLKGCLLVTLFFLTSLFPRF 160 170 180 190 200 350 360 370 380 390 400 pF1KA0 FFDHSMHSALPLGIYLATKFWMYVTWFFWFWNDLNFLFIHLPFLANSVALFYNFGKSWKS . .. :: .. :.. ::...:::. :. :: ... :. . ::..: : :.: . CCDS44 LVGYKNLVYLPTAFLLSSVFWIFMTWFILFFPDLAGAPFYFSFIFSIVAFLYFFYKTWAT 210 220 230 240 250 260 410 420 430 440 450 460 pF1KA0 DPGIIKATEEQKKKTIVELAETGSLDLSIFCSTCLIRKPVRSKHCGVCNRCIAKFDHHCP :::. ::.::.:: .:. ::::::::. ::..::::::.:: :: ::: :.:..:.:: CCDS44 DPGFTKASEEEKKVNIITLAETGSLDFRTFCTSCLIRKPLRSLHCHVCNCCVARYDQHCL 270 280 290 300 310 320 470 480 490 500 510 520 pF1KA0 WVGNCVGAGNHRYFMGYLFFLLFMIC-WMIYGCISYWGLHCETTYTKDGFWTYITQIATC :.: :.: :::.:.. .:::: :.: :.::: . : . :: ::. .::.:::..::..: CCDS44 WTGRCIGFGNHHYYIFFLFFLS-MVCGWIIYGSFIYLSSHCATTFKEDGLWTYLNQIVAC 330 340 350 360 370 380 530 540 550 560 570 580 pF1KA0 SPWMFWMFLNSVFHFMWVAVLLMCQMYQISCLGITTNERMNARRY-KHFKVTTTSIESPF :::...... ..::: : . ::. :..::. ::.:..::.. .. ::.: : . ..:. CCDS44 SPWVLYILMLATFHFSWSTFLLLNQLFQIAFLGLTSHERISLQKQSKHMKQTLSLRKTPY 390 400 410 420 430 440 590 600 610 620 630 pF1KA0 NHGCVRNIIDFFEFRCCGLFRPVIVDWTRQYTIEYDQISGSGYQLV : : ..:. :::. : :: .: .:::: :::. . CCDS44 NLGFMQNLADFFQCGCFGLVKPCVVDWTSQYTMVFHPAREKVLRSV 450 460 470 480 490 632 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 20:06:15 2016 done: Wed Nov 2 20:06:16 2016 Total Scan time: 2.320 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]