FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0946, 632 aa 1>>>pF1KA0946 632 - 632 aa - 632 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.6543+/-0.000729; mu= 12.8327+/- 0.044 mean_var=271.0372+/-57.442, 0's: 0 Z-trim(110.0): 626 B-trim: 0 in 0/53 Lambda= 0.077904 statistics sampled from 17546 (18247) to 17546 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.552), E-opt: 0.2 (0.214), width: 16 Scan time: 7.470 The best scores are: opt bits E(85289) NP_056151 (OMIM: 607799) palmitoyltransferase ZDHH ( 632) 4444 514.9 3.5e-145 XP_011536385 (OMIM: 607799) PREDICTED: palmitoyltr ( 619) 4221 489.8 1.2e-137 XP_016874582 (OMIM: 607799) PREDICTED: palmitoyltr ( 399) 2699 318.4 3e-86 XP_016874581 (OMIM: 607799) PREDICTED: palmitoyltr ( 399) 2699 318.4 3e-86 XP_016874580 (OMIM: 607799) PREDICTED: palmitoyltr ( 399) 2699 318.4 3e-86 XP_016874584 (OMIM: 607799) PREDICTED: palmitoyltr ( 360) 2592 306.3 1.2e-82 XP_005268807 (OMIM: 607799) PREDICTED: palmitoyltr ( 360) 2592 306.3 1.2e-82 XP_016874583 (OMIM: 607799) PREDICTED: palmitoyltr ( 360) 2592 306.3 1.2e-82 NP_061901 (OMIM: 612815) palmitoyltransferase ZDHH ( 622) 2096 251.0 9.5e-66 XP_011518496 (OMIM: 612815) PREDICTED: palmitoyltr ( 558) 1685 204.7 7.2e-52 XP_005253053 (OMIM: 612815) PREDICTED: palmitoyltr ( 492) 1581 192.9 2.2e-48 NP_001001483 (OMIM: 612815) palmitoyltransferase Z ( 492) 1581 192.9 2.2e-48 XP_011518497 (OMIM: 612815) PREDICTED: palmitoyltr ( 492) 1581 192.9 2.2e-48 XP_011518495 (OMIM: 612815) PREDICTED: palmitoyltr ( 464) 1070 135.4 4.2e-31 NP_932162 (OMIM: 616750) probable palmitoyltransfe ( 296) 341 53.2 1.5e-06 XP_016872255 (OMIM: 616750) PREDICTED: probable pa ( 361) 337 52.9 2.3e-06 NP_932160 (OMIM: 616750) probable palmitoyltransfe ( 361) 337 52.9 2.3e-06 XP_006718087 (OMIM: 616750) PREDICTED: probable pa ( 359) 336 52.8 2.5e-06 NP_001274732 (OMIM: 616750) probable palmitoyltran ( 359) 336 52.8 2.5e-06 NP_001305762 (OMIM: 604599) histone-lysine N-methy (1008) 322 51.9 1.3e-05 XP_016865691 (OMIM: 604599) PREDICTED: histone-lys (1183) 322 52.0 1.4e-05 XP_006715039 (OMIM: 604599) PREDICTED: histone-lys (1217) 322 52.0 1.4e-05 XP_006715038 (OMIM: 604599) PREDICTED: histone-lys (1240) 322 52.1 1.4e-05 XP_006715037 (OMIM: 604599) PREDICTED: histone-lys (1274) 322 52.1 1.4e-05 XP_016863596 (OMIM: 106410,600919) PREDICTED: anky (1797) 321 52.2 1.9e-05 XP_016863595 (OMIM: 106410,600919) PREDICTED: anky (1806) 321 52.2 1.9e-05 XP_016863591 (OMIM: 106410,600919) PREDICTED: anky (1838) 321 52.2 1.9e-05 XP_016863589 (OMIM: 106410,600919) PREDICTED: anky (1846) 321 52.2 1.9e-05 XP_016863586 (OMIM: 106410,600919) PREDICTED: anky (1858) 321 52.2 1.9e-05 XP_016863580 (OMIM: 106410,600919) PREDICTED: anky (1879) 321 52.2 1.9e-05 XP_016881362 (OMIM: 608677,615092) PREDICTED: E3 u ( 834) 315 51.0 2e-05 NP_056272 (OMIM: 614586) palmitoyltransferase ZDHH ( 715) 313 50.7 2.2e-05 XP_011543202 (OMIM: 614586) PREDICTED: palmitoyltr ( 715) 313 50.7 2.2e-05 XP_011543203 (OMIM: 614586) PREDICTED: palmitoyltr ( 715) 313 50.7 2.2e-05 XP_011543201 (OMIM: 614586) PREDICTED: palmitoyltr ( 715) 313 50.7 2.2e-05 XP_011538662 (OMIM: 611640) PREDICTED: fibronectin ( 254) 306 49.2 2.2e-05 XP_016872413 (OMIM: 611640) PREDICTED: fibronectin ( 254) 306 49.2 2.2e-05 XP_011538663 (OMIM: 611640) PREDICTED: fibronectin ( 254) 306 49.2 2.2e-05 NP_065825 (OMIM: 608677,615092) E3 ubiquitin-prote (1006) 315 51.1 2.2e-05 XP_016872411 (OMIM: 611640) PREDICTED: fibronectin ( 313) 306 49.3 2.4e-05 XP_016872410 (OMIM: 611640) PREDICTED: fibronectin ( 339) 306 49.4 2.5e-05 NP_660278 (OMIM: 611640) fibronectin type 3 and an ( 345) 306 49.4 2.6e-05 XP_006718127 (OMIM: 611640) PREDICTED: fibronectin ( 345) 306 49.4 2.6e-05 XP_011538658 (OMIM: 611640) PREDICTED: fibronectin ( 355) 306 49.4 2.6e-05 XP_006718121 (OMIM: 611640) PREDICTED: fibronectin ( 361) 306 49.4 2.6e-05 XP_016872407 (OMIM: 611640) PREDICTED: fibronectin ( 365) 306 49.4 2.6e-05 XP_011538653 (OMIM: 611640) PREDICTED: fibronectin ( 365) 306 49.4 2.6e-05 XP_016872408 (OMIM: 611640) PREDICTED: fibronectin ( 365) 306 49.4 2.6e-05 XP_016872406 (OMIM: 611640) PREDICTED: fibronectin ( 365) 306 49.4 2.6e-05 XP_011538652 (OMIM: 611640) PREDICTED: fibronectin ( 371) 306 49.4 2.7e-05 >>NP_056151 (OMIM: 607799) palmitoyltransferase ZDHHC17 (632 aa) initn: 4444 init1: 4444 opt: 4444 Z-score: 2727.5 bits: 514.9 E(85289): 3.5e-145 Smith-Waterman score: 4444; 100.0% identity (100.0% similar) in 632 aa overlap (1-632:1-632) 10 20 30 40 50 60 pF1KA0 MQREEGFNTKMADGPDEYDTEAGCVPLLHPEEIKPQSHYNHGYGEPLGRKTHIDDYSTWD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 MQREEGFNTKMADGPDEYDTEAGCVPLLHPEEIKPQSHYNHGYGEPLGRKTHIDDYSTWD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 IVKATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 IVKATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 GDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 GDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 QDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 QDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 ISLLLEAGANVDAQNIKGESALDLAKQRKNVWMINHLQEARQAKGYDNPSFLRKLKADKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 ISLLLEAGANVDAQNIKGESALDLAKQRKNVWMINHLQEARQAKGYDNPSFLRKLKADKE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 FRQKVMLGTPFLVIWLVGFIADLNIDSWLIKGLMYGGVWATVQFLSKSFFDHSMHSALPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 FRQKVMLGTPFLVIWLVGFIADLNIDSWLIKGLMYGGVWATVQFLSKSFFDHSMHSALPL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 GIYLATKFWMYVTWFFWFWNDLNFLFIHLPFLANSVALFYNFGKSWKSDPGIIKATEEQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 GIYLATKFWMYVTWFFWFWNDLNFLFIHLPFLANSVALFYNFGKSWKSDPGIIKATEEQK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 KKTIVELAETGSLDLSIFCSTCLIRKPVRSKHCGVCNRCIAKFDHHCPWVGNCVGAGNHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 KKTIVELAETGSLDLSIFCSTCLIRKPVRSKHCGVCNRCIAKFDHHCPWVGNCVGAGNHR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 YFMGYLFFLLFMICWMIYGCISYWGLHCETTYTKDGFWTYITQIATCSPWMFWMFLNSVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 YFMGYLFFLLFMICWMIYGCISYWGLHCETTYTKDGFWTYITQIATCSPWMFWMFLNSVF 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 HFMWVAVLLMCQMYQISCLGITTNERMNARRYKHFKVTTTSIESPFNHGCVRNIIDFFEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 HFMWVAVLLMCQMYQISCLGITTNERMNARRYKHFKVTTTSIESPFNHGCVRNIIDFFEF 550 560 570 580 590 600 610 620 630 pF1KA0 RCCGLFRPVIVDWTRQYTIEYDQISGSGYQLV :::::::::::::::::::::::::::::::: NP_056 RCCGLFRPVIVDWTRQYTIEYDQISGSGYQLV 610 620 630 >>XP_011536385 (OMIM: 607799) PREDICTED: palmitoyltransf (619 aa) initn: 4221 init1: 4221 opt: 4221 Z-score: 2592.1 bits: 489.8 E(85289): 1.2e-137 Smith-Waterman score: 4221; 100.0% identity (100.0% similar) in 601 aa overlap (32-632:19-619) 10 20 30 40 50 60 pF1KA0 QREEGFNTKMADGPDEYDTEAGCVPLLHPEEIKPQSHYNHGYGEPLGRKTHIDDYSTWDI :::::::::::::::::::::::::::::: XP_011 MALPDVGPFTLDYSAFRTEIKPQSHYNHGYGEPLGRKTHIDDYSTWDI 10 20 30 40 70 80 90 100 110 120 pF1KA0 VKATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VKATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGG 50 60 70 80 90 100 130 140 150 160 170 180 pF1KA0 DLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQ 110 120 130 140 150 160 190 200 210 220 230 240 pF1KA0 DVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVI 170 180 190 200 210 220 250 260 270 280 290 300 pF1KA0 SLLLEAGANVDAQNIKGESALDLAKQRKNVWMINHLQEARQAKGYDNPSFLRKLKADKEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLLLEAGANVDAQNIKGESALDLAKQRKNVWMINHLQEARQAKGYDNPSFLRKLKADKEF 230 240 250 260 270 280 310 320 330 340 350 360 pF1KA0 RQKVMLGTPFLVIWLVGFIADLNIDSWLIKGLMYGGVWATVQFLSKSFFDHSMHSALPLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RQKVMLGTPFLVIWLVGFIADLNIDSWLIKGLMYGGVWATVQFLSKSFFDHSMHSALPLG 290 300 310 320 330 340 370 380 390 400 410 420 pF1KA0 IYLATKFWMYVTWFFWFWNDLNFLFIHLPFLANSVALFYNFGKSWKSDPGIIKATEEQKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IYLATKFWMYVTWFFWFWNDLNFLFIHLPFLANSVALFYNFGKSWKSDPGIIKATEEQKK 350 360 370 380 390 400 430 440 450 460 470 480 pF1KA0 KTIVELAETGSLDLSIFCSTCLIRKPVRSKHCGVCNRCIAKFDHHCPWVGNCVGAGNHRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KTIVELAETGSLDLSIFCSTCLIRKPVRSKHCGVCNRCIAKFDHHCPWVGNCVGAGNHRY 410 420 430 440 450 460 490 500 510 520 530 540 pF1KA0 FMGYLFFLLFMICWMIYGCISYWGLHCETTYTKDGFWTYITQIATCSPWMFWMFLNSVFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FMGYLFFLLFMICWMIYGCISYWGLHCETTYTKDGFWTYITQIATCSPWMFWMFLNSVFH 470 480 490 500 510 520 550 560 570 580 590 600 pF1KA0 FMWVAVLLMCQMYQISCLGITTNERMNARRYKHFKVTTTSIESPFNHGCVRNIIDFFEFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FMWVAVLLMCQMYQISCLGITTNERMNARRYKHFKVTTTSIESPFNHGCVRNIIDFFEFR 530 540 550 560 570 580 610 620 630 pF1KA0 CCGLFRPVIVDWTRQYTIEYDQISGSGYQLV ::::::::::::::::::::::::::::::: XP_011 CCGLFRPVIVDWTRQYTIEYDQISGSGYQLV 590 600 610 >>XP_016874582 (OMIM: 607799) PREDICTED: palmitoyltransf (399 aa) initn: 2699 init1: 2699 opt: 2699 Z-score: 1669.4 bits: 318.4 E(85289): 3e-86 Smith-Waterman score: 2699; 99.7% identity (100.0% similar) in 377 aa overlap (256-632:23-399) 230 240 250 260 270 280 pF1KA0 NTALHWAVLAGNTTVISLLLEAGANVDAQNIKGESALDLAKQRKNVWMINHLQEARQAKG :.:::::::::::::::::::::::::::: XP_016 MLSWTEATAGYSRGVVTQGIAFIQGESALDLAKQRKNVWMINHLQEARQAKG 10 20 30 40 50 290 300 310 320 330 340 pF1KA0 YDNPSFLRKLKADKEFRQKVMLGTPFLVIWLVGFIADLNIDSWLIKGLMYGGVWATVQFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YDNPSFLRKLKADKEFRQKVMLGTPFLVIWLVGFIADLNIDSWLIKGLMYGGVWATVQFL 60 70 80 90 100 110 350 360 370 380 390 400 pF1KA0 SKSFFDHSMHSALPLGIYLATKFWMYVTWFFWFWNDLNFLFIHLPFLANSVALFYNFGKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKSFFDHSMHSALPLGIYLATKFWMYVTWFFWFWNDLNFLFIHLPFLANSVALFYNFGKS 120 130 140 150 160 170 410 420 430 440 450 460 pF1KA0 WKSDPGIIKATEEQKKKTIVELAETGSLDLSIFCSTCLIRKPVRSKHCGVCNRCIAKFDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WKSDPGIIKATEEQKKKTIVELAETGSLDLSIFCSTCLIRKPVRSKHCGVCNRCIAKFDH 180 190 200 210 220 230 470 480 490 500 510 520 pF1KA0 HCPWVGNCVGAGNHRYFMGYLFFLLFMICWMIYGCISYWGLHCETTYTKDGFWTYITQIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HCPWVGNCVGAGNHRYFMGYLFFLLFMICWMIYGCISYWGLHCETTYTKDGFWTYITQIA 240 250 260 270 280 290 530 540 550 560 570 580 pF1KA0 TCSPWMFWMFLNSVFHFMWVAVLLMCQMYQISCLGITTNERMNARRYKHFKVTTTSIESP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TCSPWMFWMFLNSVFHFMWVAVLLMCQMYQISCLGITTNERMNARRYKHFKVTTTSIESP 300 310 320 330 340 350 590 600 610 620 630 pF1KA0 FNHGCVRNIIDFFEFRCCGLFRPVIVDWTRQYTIEYDQISGSGYQLV ::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FNHGCVRNIIDFFEFRCCGLFRPVIVDWTRQYTIEYDQISGSGYQLV 360 370 380 390 >>XP_016874581 (OMIM: 607799) PREDICTED: palmitoyltransf (399 aa) initn: 2699 init1: 2699 opt: 2699 Z-score: 1669.4 bits: 318.4 E(85289): 3e-86 Smith-Waterman score: 2699; 99.7% identity (100.0% similar) in 377 aa overlap (256-632:23-399) 230 240 250 260 270 280 pF1KA0 NTALHWAVLAGNTTVISLLLEAGANVDAQNIKGESALDLAKQRKNVWMINHLQEARQAKG :.:::::::::::::::::::::::::::: XP_016 MLSWTEATAGYSRGVVTQGIAFIQGESALDLAKQRKNVWMINHLQEARQAKG 10 20 30 40 50 290 300 310 320 330 340 pF1KA0 YDNPSFLRKLKADKEFRQKVMLGTPFLVIWLVGFIADLNIDSWLIKGLMYGGVWATVQFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YDNPSFLRKLKADKEFRQKVMLGTPFLVIWLVGFIADLNIDSWLIKGLMYGGVWATVQFL 60 70 80 90 100 110 350 360 370 380 390 400 pF1KA0 SKSFFDHSMHSALPLGIYLATKFWMYVTWFFWFWNDLNFLFIHLPFLANSVALFYNFGKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKSFFDHSMHSALPLGIYLATKFWMYVTWFFWFWNDLNFLFIHLPFLANSVALFYNFGKS 120 130 140 150 160 170 410 420 430 440 450 460 pF1KA0 WKSDPGIIKATEEQKKKTIVELAETGSLDLSIFCSTCLIRKPVRSKHCGVCNRCIAKFDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WKSDPGIIKATEEQKKKTIVELAETGSLDLSIFCSTCLIRKPVRSKHCGVCNRCIAKFDH 180 190 200 210 220 230 470 480 490 500 510 520 pF1KA0 HCPWVGNCVGAGNHRYFMGYLFFLLFMICWMIYGCISYWGLHCETTYTKDGFWTYITQIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HCPWVGNCVGAGNHRYFMGYLFFLLFMICWMIYGCISYWGLHCETTYTKDGFWTYITQIA 240 250 260 270 280 290 530 540 550 560 570 580 pF1KA0 TCSPWMFWMFLNSVFHFMWVAVLLMCQMYQISCLGITTNERMNARRYKHFKVTTTSIESP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TCSPWMFWMFLNSVFHFMWVAVLLMCQMYQISCLGITTNERMNARRYKHFKVTTTSIESP 300 310 320 330 340 350 590 600 610 620 630 pF1KA0 FNHGCVRNIIDFFEFRCCGLFRPVIVDWTRQYTIEYDQISGSGYQLV ::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FNHGCVRNIIDFFEFRCCGLFRPVIVDWTRQYTIEYDQISGSGYQLV 360 370 380 390 >>XP_016874580 (OMIM: 607799) PREDICTED: palmitoyltransf (399 aa) initn: 2699 init1: 2699 opt: 2699 Z-score: 1669.4 bits: 318.4 E(85289): 3e-86 Smith-Waterman score: 2699; 99.7% identity (100.0% similar) in 377 aa overlap (256-632:23-399) 230 240 250 260 270 280 pF1KA0 NTALHWAVLAGNTTVISLLLEAGANVDAQNIKGESALDLAKQRKNVWMINHLQEARQAKG :.:::::::::::::::::::::::::::: XP_016 MLSWTEATAGYSRGVVTQGIAFIQGESALDLAKQRKNVWMINHLQEARQAKG 10 20 30 40 50 290 300 310 320 330 340 pF1KA0 YDNPSFLRKLKADKEFRQKVMLGTPFLVIWLVGFIADLNIDSWLIKGLMYGGVWATVQFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YDNPSFLRKLKADKEFRQKVMLGTPFLVIWLVGFIADLNIDSWLIKGLMYGGVWATVQFL 60 70 80 90 100 110 350 360 370 380 390 400 pF1KA0 SKSFFDHSMHSALPLGIYLATKFWMYVTWFFWFWNDLNFLFIHLPFLANSVALFYNFGKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKSFFDHSMHSALPLGIYLATKFWMYVTWFFWFWNDLNFLFIHLPFLANSVALFYNFGKS 120 130 140 150 160 170 410 420 430 440 450 460 pF1KA0 WKSDPGIIKATEEQKKKTIVELAETGSLDLSIFCSTCLIRKPVRSKHCGVCNRCIAKFDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WKSDPGIIKATEEQKKKTIVELAETGSLDLSIFCSTCLIRKPVRSKHCGVCNRCIAKFDH 180 190 200 210 220 230 470 480 490 500 510 520 pF1KA0 HCPWVGNCVGAGNHRYFMGYLFFLLFMICWMIYGCISYWGLHCETTYTKDGFWTYITQIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HCPWVGNCVGAGNHRYFMGYLFFLLFMICWMIYGCISYWGLHCETTYTKDGFWTYITQIA 240 250 260 270 280 290 530 540 550 560 570 580 pF1KA0 TCSPWMFWMFLNSVFHFMWVAVLLMCQMYQISCLGITTNERMNARRYKHFKVTTTSIESP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TCSPWMFWMFLNSVFHFMWVAVLLMCQMYQISCLGITTNERMNARRYKHFKVTTTSIESP 300 310 320 330 340 350 590 600 610 620 630 pF1KA0 FNHGCVRNIIDFFEFRCCGLFRPVIVDWTRQYTIEYDQISGSGYQLV ::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FNHGCVRNIIDFFEFRCCGLFRPVIVDWTRQYTIEYDQISGSGYQLV 360 370 380 390 >>XP_016874584 (OMIM: 607799) PREDICTED: palmitoyltransf (360 aa) initn: 2592 init1: 2592 opt: 2592 Z-score: 1604.9 bits: 306.3 E(85289): 1.2e-82 Smith-Waterman score: 2592; 100.0% identity (100.0% similar) in 360 aa overlap (273-632:1-360) 250 260 270 280 290 300 pF1KA0 LLLEAGANVDAQNIKGESALDLAKQRKNVWMINHLQEARQAKGYDNPSFLRKLKADKEFR :::::::::::::::::::::::::::::: XP_016 MINHLQEARQAKGYDNPSFLRKLKADKEFR 10 20 30 310 320 330 340 350 360 pF1KA0 QKVMLGTPFLVIWLVGFIADLNIDSWLIKGLMYGGVWATVQFLSKSFFDHSMHSALPLGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QKVMLGTPFLVIWLVGFIADLNIDSWLIKGLMYGGVWATVQFLSKSFFDHSMHSALPLGI 40 50 60 70 80 90 370 380 390 400 410 420 pF1KA0 YLATKFWMYVTWFFWFWNDLNFLFIHLPFLANSVALFYNFGKSWKSDPGIIKATEEQKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLATKFWMYVTWFFWFWNDLNFLFIHLPFLANSVALFYNFGKSWKSDPGIIKATEEQKKK 100 110 120 130 140 150 430 440 450 460 470 480 pF1KA0 TIVELAETGSLDLSIFCSTCLIRKPVRSKHCGVCNRCIAKFDHHCPWVGNCVGAGNHRYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TIVELAETGSLDLSIFCSTCLIRKPVRSKHCGVCNRCIAKFDHHCPWVGNCVGAGNHRYF 160 170 180 190 200 210 490 500 510 520 530 540 pF1KA0 MGYLFFLLFMICWMIYGCISYWGLHCETTYTKDGFWTYITQIATCSPWMFWMFLNSVFHF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGYLFFLLFMICWMIYGCISYWGLHCETTYTKDGFWTYITQIATCSPWMFWMFLNSVFHF 220 230 240 250 260 270 550 560 570 580 590 600 pF1KA0 MWVAVLLMCQMYQISCLGITTNERMNARRYKHFKVTTTSIESPFNHGCVRNIIDFFEFRC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MWVAVLLMCQMYQISCLGITTNERMNARRYKHFKVTTTSIESPFNHGCVRNIIDFFEFRC 280 290 300 310 320 330 610 620 630 pF1KA0 CGLFRPVIVDWTRQYTIEYDQISGSGYQLV :::::::::::::::::::::::::::::: XP_016 CGLFRPVIVDWTRQYTIEYDQISGSGYQLV 340 350 360 >>XP_005268807 (OMIM: 607799) PREDICTED: palmitoyltransf (360 aa) initn: 2592 init1: 2592 opt: 2592 Z-score: 1604.9 bits: 306.3 E(85289): 1.2e-82 Smith-Waterman score: 2592; 100.0% identity (100.0% similar) in 360 aa overlap (273-632:1-360) 250 260 270 280 290 300 pF1KA0 LLLEAGANVDAQNIKGESALDLAKQRKNVWMINHLQEARQAKGYDNPSFLRKLKADKEFR :::::::::::::::::::::::::::::: XP_005 MINHLQEARQAKGYDNPSFLRKLKADKEFR 10 20 30 310 320 330 340 350 360 pF1KA0 QKVMLGTPFLVIWLVGFIADLNIDSWLIKGLMYGGVWATVQFLSKSFFDHSMHSALPLGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QKVMLGTPFLVIWLVGFIADLNIDSWLIKGLMYGGVWATVQFLSKSFFDHSMHSALPLGI 40 50 60 70 80 90 370 380 390 400 410 420 pF1KA0 YLATKFWMYVTWFFWFWNDLNFLFIHLPFLANSVALFYNFGKSWKSDPGIIKATEEQKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YLATKFWMYVTWFFWFWNDLNFLFIHLPFLANSVALFYNFGKSWKSDPGIIKATEEQKKK 100 110 120 130 140 150 430 440 450 460 470 480 pF1KA0 TIVELAETGSLDLSIFCSTCLIRKPVRSKHCGVCNRCIAKFDHHCPWVGNCVGAGNHRYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TIVELAETGSLDLSIFCSTCLIRKPVRSKHCGVCNRCIAKFDHHCPWVGNCVGAGNHRYF 160 170 180 190 200 210 490 500 510 520 530 540 pF1KA0 MGYLFFLLFMICWMIYGCISYWGLHCETTYTKDGFWTYITQIATCSPWMFWMFLNSVFHF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MGYLFFLLFMICWMIYGCISYWGLHCETTYTKDGFWTYITQIATCSPWMFWMFLNSVFHF 220 230 240 250 260 270 550 560 570 580 590 600 pF1KA0 MWVAVLLMCQMYQISCLGITTNERMNARRYKHFKVTTTSIESPFNHGCVRNIIDFFEFRC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MWVAVLLMCQMYQISCLGITTNERMNARRYKHFKVTTTSIESPFNHGCVRNIIDFFEFRC 280 290 300 310 320 330 610 620 630 pF1KA0 CGLFRPVIVDWTRQYTIEYDQISGSGYQLV :::::::::::::::::::::::::::::: XP_005 CGLFRPVIVDWTRQYTIEYDQISGSGYQLV 340 350 360 >>XP_016874583 (OMIM: 607799) PREDICTED: palmitoyltransf (360 aa) initn: 2592 init1: 2592 opt: 2592 Z-score: 1604.9 bits: 306.3 E(85289): 1.2e-82 Smith-Waterman score: 2592; 100.0% identity (100.0% similar) in 360 aa overlap (273-632:1-360) 250 260 270 280 290 300 pF1KA0 LLLEAGANVDAQNIKGESALDLAKQRKNVWMINHLQEARQAKGYDNPSFLRKLKADKEFR :::::::::::::::::::::::::::::: XP_016 MINHLQEARQAKGYDNPSFLRKLKADKEFR 10 20 30 310 320 330 340 350 360 pF1KA0 QKVMLGTPFLVIWLVGFIADLNIDSWLIKGLMYGGVWATVQFLSKSFFDHSMHSALPLGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QKVMLGTPFLVIWLVGFIADLNIDSWLIKGLMYGGVWATVQFLSKSFFDHSMHSALPLGI 40 50 60 70 80 90 370 380 390 400 410 420 pF1KA0 YLATKFWMYVTWFFWFWNDLNFLFIHLPFLANSVALFYNFGKSWKSDPGIIKATEEQKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLATKFWMYVTWFFWFWNDLNFLFIHLPFLANSVALFYNFGKSWKSDPGIIKATEEQKKK 100 110 120 130 140 150 430 440 450 460 470 480 pF1KA0 TIVELAETGSLDLSIFCSTCLIRKPVRSKHCGVCNRCIAKFDHHCPWVGNCVGAGNHRYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TIVELAETGSLDLSIFCSTCLIRKPVRSKHCGVCNRCIAKFDHHCPWVGNCVGAGNHRYF 160 170 180 190 200 210 490 500 510 520 530 540 pF1KA0 MGYLFFLLFMICWMIYGCISYWGLHCETTYTKDGFWTYITQIATCSPWMFWMFLNSVFHF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGYLFFLLFMICWMIYGCISYWGLHCETTYTKDGFWTYITQIATCSPWMFWMFLNSVFHF 220 230 240 250 260 270 550 560 570 580 590 600 pF1KA0 MWVAVLLMCQMYQISCLGITTNERMNARRYKHFKVTTTSIESPFNHGCVRNIIDFFEFRC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MWVAVLLMCQMYQISCLGITTNERMNARRYKHFKVTTTSIESPFNHGCVRNIIDFFEFRC 280 290 300 310 320 330 610 620 630 pF1KA0 CGLFRPVIVDWTRQYTIEYDQISGSGYQLV :::::::::::::::::::::::::::::: XP_016 CGLFRPVIVDWTRQYTIEYDQISGSGYQLV 340 350 360 >>NP_061901 (OMIM: 612815) palmitoyltransferase ZDHHC13 (622 aa) initn: 2070 init1: 1025 opt: 2096 Z-score: 1301.4 bits: 251.0 E(85289): 9.5e-66 Smith-Waterman score: 2096; 51.3% identity (77.9% similar) in 571 aa overlap (53-621:45-611) 30 40 50 60 70 80 pF1KA0 GCVPLLHPEEIKPQSHYNHGYGEPLGRKTHIDDYSTWDIVKATQYGIYERCRELVEAGYD :.: :. ::::::::::.:::.:::::::: NP_061 HGPHPPGFGRYGICAHENKELANAREALPLIEDSSNCDIVKATQYGIFERCKELVEAGYD 20 30 40 50 60 70 90 100 110 120 130 140 pF1KA0 VRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQ :::::::::.::::::::::.::::.::::::.:::::::::::::::: ::::: ::. NP_061 VRQPDKENVSLLHWAAINNRLDLVKFYISKGAVVDQLGGDLNSTPLHWAIRQGHLPMVIL 80 90 100 110 120 130 150 160 170 180 190 200 pF1KA0 LMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTH :...::::.:::::: : ::::. : : :.::::.:::.:.: : ::.:::: .:... NP_061 LLQHGADPTLIDGEGFSSIHLAVLFQHMPIIAYLISKGQSVNMTDVNGQTPLMLSAHKVI 140 150 160 170 180 190 210 220 230 240 250 260 pF1KA0 SVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLEAGANVDAQNIKGESAL . .:: .:: :: :.:. :: :.:: ::::: :::..... :::::...: ::.:::. : NP_061 GPEPTGFLLKFNPSLNVVDKIHQNTPLHWAVAAGNVNAVDKLLEAGSSLDIQNVKGETPL 200 210 220 230 240 250 270 280 290 300 310 320 pF1KA0 DLAKQRKNVWMINHLQEARQAKGYDNPSFLRKLKADKEFRQKVMLGTPFLVIWLVGFIAD :.: : :: .:. :. . .. .. . : :. . : ..: ...: .:.: : NP_061 DMALQNKNQLIIHMLKTEAKMRANQKFRLWRWLQKCELF---LLLMLSVITMWAIGYILD 260 270 280 290 300 310 330 340 350 360 370 380 pF1KA0 LNIDSWLIKGLMYGGVWATVQFLSKSFFDHSMHSALPLGIYLATKFWMYVTWFFWFWNDL .: ::::.:: . .. .... . . .. :: .. :.. ::...:::. :. :: NP_061 FNSDSWLLKGCLLVTLFFLTSLFPRFLVGYKNLVYLPTAFLLSSVFWIFMTWFILFFPDL 320 330 340 350 360 370 390 400 410 420 430 440 pF1KA0 NFLFIHLPFLANSVALFYNFGKSWKSDPGIIKATEEQKKKTIVELAETGSLDLSIFCSTC ... :. . ::..: : :.: .:::. ::.::.:: .:. ::::::::. ::..: NP_061 AGAPFYFSFIFSIVAFLYFFYKTWATDPGFTKASEEEKKVNIITLAETGSLDFRTFCTSC 380 390 400 410 420 430 450 460 470 480 490 500 pF1KA0 LIRKPVRSKHCGVCNRCIAKFDHHCPWVGNCVGAGNHRYFMGYLFFLLFMIC-WMIYGCI :::::.:: :: ::: :.:..:.:: :.: :.: :::.:.. .:::: :.: :.::: . NP_061 LIRKPLRSLHCHVCNCCVARYDQHCLWTGRCIGFGNHHYYIFFLFFLS-MVCGWIIYGSF 440 450 460 470 480 490 510 520 530 540 550 560 pF1KA0 SYWGLHCETTYTKDGFWTYITQIATCSPWMFWMFLNSVFHFMWVAVLLMCQMYQISCLGI : . :: ::. .::.:::..::..::::...... ..::: : . ::. :..::. ::. NP_061 IYLSSHCATTFKEDGLWTYLNQIVACSPWVLYILMLATFHFSWSTFLLLNQLFQIAFLGL 500 510 520 530 540 550 570 580 590 600 610 620 pF1KA0 TTNERMNARRY-KHFKVTTTSIESPFNHGCVRNIIDFFEFRCCGLFRPVIVDWTRQYTIE :..::.. .. ::.: : . ..:.: : ..:. :::. : :: .: .:::: :::. NP_061 TSHERISLQKQSKHMKQTLSLRKTPYNLGFMQNLADFFQCGCFGLVKPCVVDWTSQYTMV 560 570 580 590 600 610 630 pF1KA0 YDQISGSGYQLV . NP_061 FHPAREKVLRSV 620 >>XP_011518496 (OMIM: 612815) PREDICTED: palmitoyltransf (558 aa) initn: 1664 init1: 1025 opt: 1685 Z-score: 1052.2 bits: 204.7 E(85289): 7.2e-52 Smith-Waterman score: 1685; 53.2% identity (77.7% similar) in 457 aa overlap (53-504:65-517) 30 40 50 60 70 80 pF1KA0 GCVPLLHPEEIKPQSHYNHGYGEPLGRKTHIDDYSTWDIVKATQYGIYERCRELVEAGYD :.: :. ::::::::::.:::.:::::::: XP_011 HGPHPPGFGRYGICAHENKELANAREALPLIEDSSNCDIVKATQYGIFERCKELVEAGYD 40 50 60 70 80 90 90 100 110 120 130 140 pF1KA0 VRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQ :::::::::.::::::::::.::::.::::::.:::::::::::::::: ::::: ::. XP_011 VRQPDKENVSLLHWAAINNRLDLVKFYISKGAVVDQLGGDLNSTPLHWAIRQGHLPMVIL 100 110 120 130 140 150 150 160 170 180 190 200 pF1KA0 LMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTH :...::::.:::::: : ::::. : : :.::::.:::.:.: : ::.:::: .:... XP_011 LLQHGADPTLIDGEGFSSIHLAVLFQHMPIIAYLISKGQSVNMTDVNGQTPLMLSAHKVI 160 170 180 190 200 210 210 220 230 240 250 260 pF1KA0 SVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLEAGANVDAQNIKGESAL . .:: .:: :: :.:. :: :.:: ::::: :::..... :::::...: ::.:::. : XP_011 GPEPTGFLLKFNPSLNVVDKIHQNTPLHWAVAAGNVNAVDKLLEAGSSLDIQNVKGETPL 220 230 240 250 260 270 270 280 290 300 310 320 pF1KA0 DLAKQRKNVWMINHLQEARQAKGYDNPSFLRKLKADKEFRQKVMLGTPFLVIWLVGFIAD :.: : :: .:. :. . .. .. . : :. . : ..: ...: .:.: : XP_011 DMALQNKNQLIIHMLKTEAKMRANQKFRLWRWLQKCELF---LLLMLSVITMWAIGYILD 280 290 300 310 320 330 330 340 350 360 370 380 pF1KA0 LNIDSWLIKGLMYGGVWATVQFLSKSFFDHSMHSALPLGIYLATKFWMYVTWFFWFWNDL .: ::::.:: . .. .... . . .. :: .. :.. ::...:::. :. :: XP_011 FNSDSWLLKGCLLVTLFFLTSLFPRFLVGYKNLVYLPTAFLLSSVFWIFMTWFILFFPDL 340 350 360 370 380 390 390 400 410 420 430 440 pF1KA0 NFLFIHLPFLANSVALFYNFGKSWKSDPGIIKATEEQKKKTIVELAETGSLDLSIFCSTC ... :. . ::..: : :.: .:::. ::.::.:: .:. ::::::::. ::..: XP_011 AGAPFYFSFIFSIVAFLYFFYKTWATDPGFTKASEEEKKVNIITLAETGSLDFRTFCTSC 400 410 420 430 440 450 450 460 470 480 490 pF1KA0 LIRKPVRSKHCGVCNRCIAKFDHHCPWVGNCVGAGNHRYFMGYLFFLLFMIC-WMIYG-- :::::.:: :: ::: :.:..:.:: :.: :.: :::.:.. .:::: :.: :.::: XP_011 LIRKPLRSLHCHVCNCCVARYDQHCLWTGRCIGFGNHHYYIFFLFFLS-MVCGWIIYGSF 460 470 480 490 500 510 500 510 520 530 540 550 pF1KA0 -CI-SYWGLHCETTYTKDGFWTYITQIATCSPWMFWMFLNSVFHFMWVAVLLMCQMYQIS :. . : XP_011 ICLFTRWIVSDSKSVSILQVTERKIVDYHQEELCNCQSHLKMKTFDLE 520 530 540 550 632 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 20:06:16 2016 done: Wed Nov 2 20:06:17 2016 Total Scan time: 7.470 Total Display time: 0.080 Function used was FASTA [36.3.4 Apr, 2011]