FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0947, 2266 aa 1>>>pF1KA0947 2266 - 2266 aa - 2266 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 12.3781+/-0.00132; mu= -6.5373+/- 0.079 mean_var=357.0310+/-74.739, 0's: 0 Z-trim(111.9): 21 B-trim: 399 in 1/50 Lambda= 0.067877 statistics sampled from 12769 (12782) to 12769 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.705), E-opt: 0.2 (0.393), width: 16 Scan time: 7.970 The best scores are: opt bits E(32554) CCDS47187.1 ICE1 gene_id:23379|Hs108|chr5 (2266) 14932 1478.0 0 >>CCDS47187.1 ICE1 gene_id:23379|Hs108|chr5 (2266 aa) initn: 14932 init1: 14932 opt: 14932 Z-score: 7912.6 bits: 1478.0 E(32554): 0 Smith-Waterman score: 14932; 99.9% identity (100.0% similar) in 2266 aa overlap (1-2266:1-2266) 10 20 30 40 50 60 pF1KA0 MMPGETHSAAPGTAADLSRCQGCASLQQNLNEYVEALITLKQKIINTDNLLTEYQKKCDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 MMPGETHSAAPGTAADLSRCQGCASLQQNLNEYVEALITLKQKIINTDNLLTEYQKKCDE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 LQFARRENSNLHHQVEEMLQKISPLQKCQEELGSLKAELEEKKSSLKLYQDTHQEYARVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 LQFARRENSNLHHQVEEMLQKISPLQKCQEELGSLKAELEEKKSSLKLYQDTHQEYARVK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 EECLKSDAQKKKLEAKVKKLQEAAVKQTQDFKQLRNEKKILEKEFKKTQERLDEFSKQKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 EECLKSDAQKKKLEAKVKKLQEAAVKQTQDFKQLRNEKKILEKEFKKTQERLDEFSKQKN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 EKELRHIGTQISSDSYGSIDKRKVKLLLKELWLCVNTTHRLPGEGSRCVPEKPAKAITSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 EKELRHIGTQISSDSYGSIDKRKVKLLLKELWLCVNTTHRLPGEGSRCVPEKPAKAITSS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 RVPGEDGTLPPTQGSPLRTSNVQTCLTKLSMEIKEDFLCQNVEKQSSSGTNCSSDHVFNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 RVPGEDGTLPPTQGSPLRTSNVQTCLTKLSMEIKEDFLCQNVEKQSSSGTNCSSDHVFNE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 NGNLEVLVQSHRDGGSTEFVDHDHFFDEDLQAAIDFFKLPPPLLSPVPSPPPMSSPHPGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 NGNLEVLVQSHRDGGSTEFVDHDHFFDEDLQAAIDFFKLPPPLLSPVPSPPPMSSPHPGS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 LPSSFAPETYFGEYTDSSDNDSVQLRNSAESVSEDDTTESQNYFGSLRKNKGSGTWEEKP :::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::: CCDS47 LPSSFAPETYFGEYTDSSDNDSVQLRNSAECVSEDDTTESQNYFGSLRKNKGSGTWEEKP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 KSHEAIQALNTWEVNKVTTSGLETFTATLRESSATHSLVGEKHWTTASRSMSDRKRDILH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 KSHEAIQALNTWEVNKVTTSGLETFTATLRESSATHSLVGEKHWTTASRSMSDRKRDILH 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 ETKTQMEVREMDKSVQTEKTIHKLTRGLCIERLSASPAQEKEAAPGKSELCSSPLGKRPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 ETKTQMEVREMDKSVQTEKTIHKLTRGLCIERLSASPAQEKEAAPGKSELCSSPLGKRPL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 NELMESEGKTVLSKMMGSPKSEFTKWTRINEITSEPDRITVSGHFHRLSRELEKEKEDTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 NELMESEGKTVLSKMMGSPKSEFTKWTRINEITSEPDRITVSGHFHRLSRELEKEKEDTQ 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 GFTLGESPESEDDDSGDGMDVAGLDIETSFSSSSTLVALSVGSNPQSSSGLDCGNDTDIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 GFTLGESPESEDDDSGDGMDVAGLDIETSFSSSSTLVALSVGSNPQSSSGLDCGNDTDIT 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 TKVFSTEPHHSEHKLQTKTLNTLHLQSEPPECSIGGNNLENSLCALSPELGASNFNDQKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 TKVFSTEPHHSEHKLQTKTLNTLHLQSEPPECSIGGNNLENSLCALSPELGASNFNDQKS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 SGIEYTKVVKGLTKIHSLPRSVFMKATKDGQCESQDPRIELTLNKPDFTSLIGSQAALIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 SGIEYTKVVKGLTKIHSLPRSVFMKATKDGQCESQDPRIELTLNKPDFTSLIGSQAALIK 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 SGLGFVKSTSWHHSDLLRKGGEESLRAKSEHEQKTSHQLQKAMPFLQNRGPTPKPDLLRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 SGLGFVKSTSWHHSDLLRKGGEESLRAKSEHEQKTSHQLQKAMPFLQNRGPTPKPDLLRE 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 NNNPVEFKTTASVLPNQVSVITKQTRPEKVQSAKLEHLRPHRVEPTLVTENSGNKTGMST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 NNNPVEFKTTASVLPNQVSVITKQTRPEKVQSAKLEHLRPHRVEPTLVTENSGNKTGMST 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 IAKCDGERDDTTQNITEVAAVKSISPEVSASRRKLDFNSPGGSSPVENSDCSTNSRLSFS .::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 VAKCDGERDDTTQNITEVAAVKSISPEVSASRRKLDFNSPGGSSPVENSDCSTNSRLSFS 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 PENILIQNQDIVREAAVQGDGQKQRQPQATDLDSSGTHGSEMLPATEVTVSGGFSVEETS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 PENILIQNQDIVREAAVQGDGQKQRQPQATDLDSSGTHGSEMLPATEVTVSGGFSVEETS 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 CGDTGRSGGEALAVANDSTSTPQNANGLWKLKSTTPGGALPECFGTTDTTFSSAFCRKHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 CGDTGRSGGEALAVANDSTSTPQNANGLWKLKSTTPGGALPECFGTTDTTFSSAFCRKHG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 ETQDTSQSSLPGTLHCYTGIREGGDDTEVESEAFSCSEGSEQQDAPDDSQKNLGDTDAAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 ETQDTSQSSLPGTLHCYTGIREGGDDTEVESEAFSCSEGSEQQDAPDDSQKNLGDTDAAV 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA0 AEVRPSLEVGYLTSALQDFNISTFSELDRLSTSEVVMFLESCQLGDYSSGDSVSECSSKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 AEVRPSLEVGYLTSALQDFNISTFSELDRLSTSEVVMFLESCQLGDYSSGDSVSECSSKG 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA0 TLSKEMNKELKASEIGEKYRKQPCEEETLGTCEEWIESEEDDYSLKNTSQLTQCSLETLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 TLSKEMNKELKASEIGEKYRKQPCEEETLGTCEEWIESEEDDYSLKNTSQLTQCSLETLS 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA0 EVLTKIRQELQTNSEDCNGKDTGSLLLLNVNNNMTTENLKEKSPFRETTGSSSHASEPTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 EVLTKIRQELQTNSEDCNGKDTGSLLLLNVNNNMTTENLKEKSPFRETTGSSSHASEPTP 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA0 QAAALDTEGSSPISGMPQNENPQSRPEARSDAGRQTDGGEEDLPEPVEPSALCSDSVMEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 QAAALDTEGSSPISGMPQNENPQSRPEARSDAGRQTDGGEEDLPEPVEPSALCSDSVMEP 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA0 SIEQSSNCEAETTFQCQIATVTSEVINVLINKDQNLVIEKGDNWTIISGVAVLPHVDQVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 SIEQSSNCEAETTFQCQIATVTSEVINVLINKDQNLVIEKGDNWTIISGVAVLPHVDQVT 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA0 LCDIPGDIPISQDQGELEAGCIPVTSAEKSPEASHTGPAFQEAPCGNNLSCPQEDVSSSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 LCDIPGDIPISQDQGELEAGCIPVTSAEKSPEASHTGPAFQEAPCGNNLSCPQEDVSSSG 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA0 QSTNFDKSRLRNRPVKPSIWISSQIYDQNFETQIVASDHTYYNSKLEPSGKNKNRSKISN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 QSTNFDKSRLRNRPVKPSIWISSQIYDQNFETQIVASDHTYYNSKLEPSGKNKNRSKISN 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA0 KDQSNKPVKTSASSRVETHQSEVAQSFSGEKANTKTQRSQTQTILANADTSTPTDCSPDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 KDQSNKPVKTSASSRVETHQSEVAQSFSGEKANTKTQRSQTQTILANADTSTPTDCSPDT 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA0 LSKIRQEVGPPLPPLLAPLIATPPRTSQPLSPLISSSSPSSPASPVGQVSPFRETPVPPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 LSKIRQEVGPPLPPLLAPLIATPPRTSQPLSPLISSSSPSSPASPVGQVSPFRETPVPPA 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KA0 MSPWPEDPRRASPPDPSPSPSAASASERVVPSPLQFCAATPKHALPVPGRLPPCASGHAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 MSPWPEDPRRASPPDPSPSPSAASASERVVPSPLQFCAATPKHALPVPGRLPPCASGHAA 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KA0 VGGPQENSVKILDTMYPELSARARTLNILKGNIQLTRGPPADCKNLPGPASAMIGFKTIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 VGGPQENSVKILDTMYPELSARARTLNILKGNIQLTRGPPADCKNLPGPASAMIGFKTIT 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KA0 SAATAFVKTGSSSGGDCNQDKSRDLGTQQDSSGKRTLSTSTLRSAKRLRLDTGSPEPETR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 SAATAFVKTGSSSGGDCNQDKSRDLGTQQDSSGKRTLSTSTLRSAKRLRLDTGSPEPETR 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KA0 GVTAEGIHKNLPGNLPPAEVATTNEERSCSSPAVSAVSQLPLSPKETVESHDKAIANALK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 GVTAEGIHKNLPGNLPPAEVATTNEERSCSSPAVSAVSQLPLSPKETVESHDKAIANALK 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KA0 KIAEFSFDLLPVIRSHVYVGNISKKPVMRDQEKEVVYEFSTTKKHLAECLLHSILSELKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 KIAEFSFDLLPVIRSHVYVGNISKKPVMRDQEKEVVYEFSTTKKHLAECLLHSILSELKI 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KA0 QKISMDHNYIHALCRVYVGICRQLGDLERARLFCYSLLKEDFPESEKLTLFIANMWHDIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 QKISMDHNYIHALCRVYVGICRQLGDLERARLFCYSLLKEDFPESEKLTLFIANMWHDIF 1990 2000 2010 2020 2030 2040 2050 2060 2070 2080 2090 2100 pF1KA0 LSQSVINKAMQLVARQRAKGEVLNCLRAFLNWEKNAPVDVGFMVSKLLLTIQLCPKTEFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 LSQSVINKAMQLVARQRAKGEVLNCLRAFLNWEKNAPVDVGFMVSKLLLTIQLCPKTEFQ 2050 2060 2070 2080 2090 2100 2110 2120 2130 2140 2150 2160 pF1KA0 PSEKFGEDLSDNTWEYIFAIDLLCCHQKWIWTHDNIISKELWPVMDKWIKYRKGHANIAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 PSEKFGEDLSDNTWEYIFAIDLLCCHQKWIWTHDNIISKELWPVMDKWIKYRKGHANIAY 2110 2120 2130 2140 2150 2160 2170 2180 2190 2200 2210 2220 pF1KA0 TPDIIIASILRLIGRLGQLGLKEGFPSAVKNISSVIGMFIQHAHDEDIPWGIQLAAVYAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 TPDIIIASILRLIGRLGQLGLKEGFPSAVKNISSVIGMFIQHAHDEDIPWGIQLAAVYAL 2170 2180 2190 2200 2210 2220 2230 2240 2250 2260 pF1KA0 CDLSPSNPAEISKILEAWRREASKSVPSAIVSCLEEVSALSTEELG :::::::::::::::::::::::::::::::::::::::::::::: CCDS47 CDLSPSNPAEISKILEAWRREASKSVPSAIVSCLEEVSALSTEELG 2230 2240 2250 2260 2266 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 10:34:30 2016 done: Thu Nov 3 10:34:31 2016 Total Scan time: 7.970 Total Display time: 0.240 Function used was FASTA [36.3.4 Apr, 2011]