FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0950, 316 aa 1>>>pF1KA0950 316 - 316 aa - 316 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.6039+/-0.000329; mu= 12.0826+/- 0.021 mean_var=126.3293+/-25.258, 0's: 0 Z-trim(119.0): 20 B-trim: 106 in 1/53 Lambda= 0.114110 statistics sampled from 32615 (32635) to 32615 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.722), E-opt: 0.2 (0.383), width: 16 Scan time: 7.590 The best scores are: opt bits E(85289) NP_036438 (OMIM: 604306) protein lifeguard 2 [Homo ( 316) 2116 358.9 7.6e-99 XP_016874529 (OMIM: 604306) PREDICTED: protein lif ( 316) 2116 358.9 7.6e-99 XP_005268787 (OMIM: 604306) PREDICTED: protein lif ( 274) 1652 282.5 6.8e-76 NP_001308356 (OMIM: 610364) protein lifeguard 3 is ( 311) 984 172.6 9.5e-43 XP_011509929 (OMIM: 610364) PREDICTED: protein lif ( 311) 984 172.6 9.5e-43 NP_001308365 (OMIM: 610364) protein lifeguard 3 is ( 311) 984 172.6 9.5e-43 NP_001308359 (OMIM: 610364) protein lifeguard 3 is ( 311) 984 172.6 9.5e-43 NP_071435 (OMIM: 610364) protein lifeguard 3 isofo ( 311) 984 172.6 9.5e-43 NP_001308364 (OMIM: 610364) protein lifeguard 3 is ( 311) 984 172.6 9.5e-43 NP_001308358 (OMIM: 610364) protein lifeguard 3 is ( 311) 984 172.6 9.5e-43 NP_001308361 (OMIM: 610364) protein lifeguard 3 is ( 311) 984 172.6 9.5e-43 NP_001308362 (OMIM: 610364) protein lifeguard 3 is ( 311) 984 172.6 9.5e-43 NP_001308357 (OMIM: 610364) protein lifeguard 3 is ( 311) 984 172.6 9.5e-43 NP_000828 (OMIM: 138251) protein lifeguard 1 [Homo ( 371) 835 148.1 2.6e-35 NP_001009184 (OMIM: 138251) protein lifeguard 1 [H ( 371) 835 148.1 2.6e-35 NP_001308367 (OMIM: 610364) protein lifeguard 3 is ( 200) 771 137.3 2.4e-32 NP_057140 (OMIM: 616874) protein lifeguard 4 isofo ( 238) 375 72.2 1.2e-12 NP_001269535 (OMIM: 616874) protein lifeguard 4 is ( 285) 364 70.5 4.7e-12 NP_001269539 (OMIM: 616874) protein lifeguard 4 is ( 207) 311 61.6 1.6e-09 NP_001269538 (OMIM: 616874) protein lifeguard 4 is ( 162) 217 46.1 5.9e-05 >>NP_036438 (OMIM: 604306) protein lifeguard 2 [Homo sap (316 aa) initn: 2116 init1: 2116 opt: 2116 Z-score: 1895.5 bits: 358.9 E(85289): 7.6e-99 Smith-Waterman score: 2116; 100.0% identity (100.0% similar) in 316 aa overlap (1-316:1-316) 10 20 30 40 50 60 pF1KA0 MTQGKLSVANKAPGTEGQQQVHGEKKEAPAVPSAPPSYEEATSGEGMKAGAFPPAPTAVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 MTQGKLSVANKAPGTEGQQQVHGEKKEAPAVPSAPPSYEEATSGEGMKAGAFPPAPTAVP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 LHPSWAYVDPSSSSSYDNGFPTGDHELFTTFSWDDQKVRRVFVRKVYTILLIQLLVTLAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 LHPSWAYVDPSSSSSYDNGFPTGDHELFTTFSWDDQKVRRVFVRKVYTILLIQLLVTLAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 VALFTFCDPVKDYVQANPGWYWASYAVFFATYLTLACCSGPRRHFPWNLILLTVFTLSMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 VALFTFCDPVKDYVQANPGWYWASYAVFFATYLTLACCSGPRRHFPWNLILLTVFTLSMA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 YLTGMLSSYYNTTSVLLCLGITALVCLSVTVFSFQTKFDFTSCQGVLFVLLMTLFFSGLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 YLTGMLSSYYNTTSVLLCLGITALVCLSVTVFSFQTKFDFTSCQGVLFVLLMTLFFSGLI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 LAILLPFQYVPWLHAVYAALGAGVFTLFLALDTQLLMGNRRHSLSPEEYIFGALNIYLDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 LAILLPFQYVPWLHAVYAALGAGVFTLFLALDTQLLMGNRRHSLSPEEYIFGALNIYLDI 250 260 270 280 290 300 310 pF1KA0 IYIFTFFLQLFGTNRE :::::::::::::::: NP_036 IYIFTFFLQLFGTNRE 310 >>XP_016874529 (OMIM: 604306) PREDICTED: protein lifegua (316 aa) initn: 2116 init1: 2116 opt: 2116 Z-score: 1895.5 bits: 358.9 E(85289): 7.6e-99 Smith-Waterman score: 2116; 100.0% identity (100.0% similar) in 316 aa overlap (1-316:1-316) 10 20 30 40 50 60 pF1KA0 MTQGKLSVANKAPGTEGQQQVHGEKKEAPAVPSAPPSYEEATSGEGMKAGAFPPAPTAVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MTQGKLSVANKAPGTEGQQQVHGEKKEAPAVPSAPPSYEEATSGEGMKAGAFPPAPTAVP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 LHPSWAYVDPSSSSSYDNGFPTGDHELFTTFSWDDQKVRRVFVRKVYTILLIQLLVTLAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHPSWAYVDPSSSSSYDNGFPTGDHELFTTFSWDDQKVRRVFVRKVYTILLIQLLVTLAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 VALFTFCDPVKDYVQANPGWYWASYAVFFATYLTLACCSGPRRHFPWNLILLTVFTLSMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VALFTFCDPVKDYVQANPGWYWASYAVFFATYLTLACCSGPRRHFPWNLILLTVFTLSMA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 YLTGMLSSYYNTTSVLLCLGITALVCLSVTVFSFQTKFDFTSCQGVLFVLLMTLFFSGLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLTGMLSSYYNTTSVLLCLGITALVCLSVTVFSFQTKFDFTSCQGVLFVLLMTLFFSGLI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 LAILLPFQYVPWLHAVYAALGAGVFTLFLALDTQLLMGNRRHSLSPEEYIFGALNIYLDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LAILLPFQYVPWLHAVYAALGAGVFTLFLALDTQLLMGNRRHSLSPEEYIFGALNIYLDI 250 260 270 280 290 300 310 pF1KA0 IYIFTFFLQLFGTNRE :::::::::::::::: XP_016 IYIFTFFLQLFGTNRE 310 >>XP_005268787 (OMIM: 604306) PREDICTED: protein lifegua (274 aa) initn: 1634 init1: 1634 opt: 1652 Z-score: 1483.6 bits: 282.5 E(85289): 6.8e-76 Smith-Waterman score: 1652; 94.7% identity (96.6% similar) in 266 aa overlap (55-316:9-274) 30 40 50 60 70 80 pF1KA0 KKEAPAVPSAPPSYEEATSGEGMKAGAFPPAPTAVPL--HPSWAY--VDPSSSSSYDNGF .: :: ::. .: :. .::::::::: XP_005 MVYTSHYKSPGRRPLKTHPTVTYWRVNEGSSSSYDNGF 10 20 30 90 100 110 120 130 140 pF1KA0 PTGDHELFTTFSWDDQKVRRVFVRKVYTILLIQLLVTLAVVALFTFCDPVKDYVQANPGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PTGDHELFTTFSWDDQKVRRVFVRKVYTILLIQLLVTLAVVALFTFCDPVKDYVQANPGW 40 50 60 70 80 90 150 160 170 180 190 200 pF1KA0 YWASYAVFFATYLTLACCSGPRRHFPWNLILLTVFTLSMAYLTGMLSSYYNTTSVLLCLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YWASYAVFFATYLTLACCSGPRRHFPWNLILLTVFTLSMAYLTGMLSSYYNTTSVLLCLG 100 110 120 130 140 150 210 220 230 240 250 260 pF1KA0 ITALVCLSVTVFSFQTKFDFTSCQGVLFVLLMTLFFSGLILAILLPFQYVPWLHAVYAAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ITALVCLSVTVFSFQTKFDFTSCQGVLFVLLMTLFFSGLILAILLPFQYVPWLHAVYAAL 160 170 180 190 200 210 270 280 290 300 310 pF1KA0 GAGVFTLFLALDTQLLMGNRRHSLSPEEYIFGALNIYLDIIYIFTFFLQLFGTNRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GAGVFTLFLALDTQLLMGNRRHSLSPEEYIFGALNIYLDIIYIFTFFLQLFGTNRE 220 230 240 250 260 270 >>NP_001308356 (OMIM: 610364) protein lifeguard 3 isofor (311 aa) initn: 1023 init1: 935 opt: 984 Z-score: 888.5 bits: 172.6 E(85289): 9.5e-43 Smith-Waterman score: 987; 52.0% identity (74.0% similar) in 300 aa overlap (13-312:23-308) 10 20 30 40 50 pF1KA0 MTQGKLSVANKAPGTEGQQQVHGEKKEAPAVPSAPPSYEEATSGEGMKAG :: :: .: :. : :.: . : : :: NP_001 MSNPSAPPPYEDRNPLYPGPPPPGGYGQPSV------LPGGYPAYPGYPQP--GYGHPAG 10 20 30 40 50 60 70 80 90 100 110 pF1KA0 AFPPAPTAVPLHPSWAYVDPSSSSSYDNGFPTGDHELFTTFSWDDQKVRRVFVRKVYTIL : : : :: :. .:: : . . : :::.:::..:.::::.:. NP_001 YPQPMP---PTHPMPMNYGPGH--GYD-GEERAVSDSFGPGEWDDRKVRHTFIRKVYSII 60 70 80 90 100 120 130 140 150 160 170 pF1KA0 LIQLLVTLAVVALFTFCDPVKDYVQANPGWYWASYAVFFATYLTLACCSGPRRHFPWNLI .:::.:.:..:.::: .::. .:. : . :..::::: .::: ::::.::::.::::.: NP_001 SVQLLITVAIIAIFTFVEPVSAFVRRNVAVYYVSYAVFVVTYLILACCQGPRRRFPWNII 110 120 130 140 150 160 180 190 200 210 220 230 pF1KA0 LLTVFTLSMAYLTGMLSSYYNTTSVLLCLGITALVCLSVTVFSFQTKFDFTSCQGVLFVL :::.::..:...:: .::.:.: .:.. . :::.: .:::.: :::: ::::: :.. :: NP_001 LLTLFTFAMGFMTGTISSMYQTKAVIIAMIITAVVSISVTIFCFQTKVDFTSCTGLFCVL 170 180 190 200 210 220 240 250 260 270 280 290 pF1KA0 LMTLFFSGLILAILLPFQYVPWLHAVYAALGAGVFTLFLALDTQLLMGNRRHSLSPEEYI ..:. .:.. .:.: :::: ::: .:::::: :::::: ::::..:::.:..:::.:: NP_001 GIVLLVTGIVTSIVLYFQYVYWLHMLYAALGAICFTLFLAYDTQLVLGNRKHTISPEDYI 230 240 250 260 270 280 300 310 pF1KA0 FGALNIYLDIIYIFTFFLQLFGTNRE :::.:: :::::::: :::.: NP_001 TGALQIYTDIIYIFTFVLQLMGDRN 290 300 310 >>XP_011509929 (OMIM: 610364) PREDICTED: protein lifegua (311 aa) initn: 1023 init1: 935 opt: 984 Z-score: 888.5 bits: 172.6 E(85289): 9.5e-43 Smith-Waterman score: 987; 52.0% identity (74.0% similar) in 300 aa overlap (13-312:23-308) 10 20 30 40 50 pF1KA0 MTQGKLSVANKAPGTEGQQQVHGEKKEAPAVPSAPPSYEEATSGEGMKAG :: :: .: :. : :.: . : : :: XP_011 MSNPSAPPPYEDRNPLYPGPPPPGGYGQPSV------LPGGYPAYPGYPQP--GYGHPAG 10 20 30 40 50 60 70 80 90 100 110 pF1KA0 AFPPAPTAVPLHPSWAYVDPSSSSSYDNGFPTGDHELFTTFSWDDQKVRRVFVRKVYTIL : : : :: :. .:: : . . : :::.:::..:.::::.:. XP_011 YPQPMP---PTHPMPMNYGPGH--GYD-GEERAVSDSFGPGEWDDRKVRHTFIRKVYSII 60 70 80 90 100 120 130 140 150 160 170 pF1KA0 LIQLLVTLAVVALFTFCDPVKDYVQANPGWYWASYAVFFATYLTLACCSGPRRHFPWNLI .:::.:.:..:.::: .::. .:. : . :..::::: .::: ::::.::::.::::.: XP_011 SVQLLITVAIIAIFTFVEPVSAFVRRNVAVYYVSYAVFVVTYLILACCQGPRRRFPWNII 110 120 130 140 150 160 180 190 200 210 220 230 pF1KA0 LLTVFTLSMAYLTGMLSSYYNTTSVLLCLGITALVCLSVTVFSFQTKFDFTSCQGVLFVL :::.::..:...:: .::.:.: .:.. . :::.: .:::.: :::: ::::: :.. :: XP_011 LLTLFTFAMGFMTGTISSMYQTKAVIIAMIITAVVSISVTIFCFQTKVDFTSCTGLFCVL 170 180 190 200 210 220 240 250 260 270 280 290 pF1KA0 LMTLFFSGLILAILLPFQYVPWLHAVYAALGAGVFTLFLALDTQLLMGNRRHSLSPEEYI ..:. .:.. .:.: :::: ::: .:::::: :::::: ::::..:::.:..:::.:: XP_011 GIVLLVTGIVTSIVLYFQYVYWLHMLYAALGAICFTLFLAYDTQLVLGNRKHTISPEDYI 230 240 250 260 270 280 300 310 pF1KA0 FGALNIYLDIIYIFTFFLQLFGTNRE :::.:: :::::::: :::.: XP_011 TGALQIYTDIIYIFTFVLQLMGDRN 290 300 310 >>NP_001308365 (OMIM: 610364) protein lifeguard 3 isofor (311 aa) initn: 1023 init1: 935 opt: 984 Z-score: 888.5 bits: 172.6 E(85289): 9.5e-43 Smith-Waterman score: 987; 52.0% identity (74.0% similar) in 300 aa overlap (13-312:23-308) 10 20 30 40 50 pF1KA0 MTQGKLSVANKAPGTEGQQQVHGEKKEAPAVPSAPPSYEEATSGEGMKAG :: :: .: :. : :.: . : : :: NP_001 MSNPSAPPPYEDRNPLYPGPPPPGGYGQPSV------LPGGYPAYPGYPQP--GYGHPAG 10 20 30 40 50 60 70 80 90 100 110 pF1KA0 AFPPAPTAVPLHPSWAYVDPSSSSSYDNGFPTGDHELFTTFSWDDQKVRRVFVRKVYTIL : : : :: :. .:: : . . : :::.:::..:.::::.:. NP_001 YPQPMP---PTHPMPMNYGPGH--GYD-GEERAVSDSFGPGEWDDRKVRHTFIRKVYSII 60 70 80 90 100 120 130 140 150 160 170 pF1KA0 LIQLLVTLAVVALFTFCDPVKDYVQANPGWYWASYAVFFATYLTLACCSGPRRHFPWNLI .:::.:.:..:.::: .::. .:. : . :..::::: .::: ::::.::::.::::.: NP_001 SVQLLITVAIIAIFTFVEPVSAFVRRNVAVYYVSYAVFVVTYLILACCQGPRRRFPWNII 110 120 130 140 150 160 180 190 200 210 220 230 pF1KA0 LLTVFTLSMAYLTGMLSSYYNTTSVLLCLGITALVCLSVTVFSFQTKFDFTSCQGVLFVL :::.::..:...:: .::.:.: .:.. . :::.: .:::.: :::: ::::: :.. :: NP_001 LLTLFTFAMGFMTGTISSMYQTKAVIIAMIITAVVSISVTIFCFQTKVDFTSCTGLFCVL 170 180 190 200 210 220 240 250 260 270 280 290 pF1KA0 LMTLFFSGLILAILLPFQYVPWLHAVYAALGAGVFTLFLALDTQLLMGNRRHSLSPEEYI ..:. .:.. .:.: :::: ::: .:::::: :::::: ::::..:::.:..:::.:: NP_001 GIVLLVTGIVTSIVLYFQYVYWLHMLYAALGAICFTLFLAYDTQLVLGNRKHTISPEDYI 230 240 250 260 270 280 300 310 pF1KA0 FGALNIYLDIIYIFTFFLQLFGTNRE :::.:: :::::::: :::.: NP_001 TGALQIYTDIIYIFTFVLQLMGDRN 290 300 310 >>NP_001308359 (OMIM: 610364) protein lifeguard 3 isofor (311 aa) initn: 1023 init1: 935 opt: 984 Z-score: 888.5 bits: 172.6 E(85289): 9.5e-43 Smith-Waterman score: 987; 52.0% identity (74.0% similar) in 300 aa overlap (13-312:23-308) 10 20 30 40 50 pF1KA0 MTQGKLSVANKAPGTEGQQQVHGEKKEAPAVPSAPPSYEEATSGEGMKAG :: :: .: :. : :.: . : : :: NP_001 MSNPSAPPPYEDRNPLYPGPPPPGGYGQPSV------LPGGYPAYPGYPQP--GYGHPAG 10 20 30 40 50 60 70 80 90 100 110 pF1KA0 AFPPAPTAVPLHPSWAYVDPSSSSSYDNGFPTGDHELFTTFSWDDQKVRRVFVRKVYTIL : : : :: :. .:: : . . : :::.:::..:.::::.:. NP_001 YPQPMP---PTHPMPMNYGPGH--GYD-GEERAVSDSFGPGEWDDRKVRHTFIRKVYSII 60 70 80 90 100 120 130 140 150 160 170 pF1KA0 LIQLLVTLAVVALFTFCDPVKDYVQANPGWYWASYAVFFATYLTLACCSGPRRHFPWNLI .:::.:.:..:.::: .::. .:. : . :..::::: .::: ::::.::::.::::.: NP_001 SVQLLITVAIIAIFTFVEPVSAFVRRNVAVYYVSYAVFVVTYLILACCQGPRRRFPWNII 110 120 130 140 150 160 180 190 200 210 220 230 pF1KA0 LLTVFTLSMAYLTGMLSSYYNTTSVLLCLGITALVCLSVTVFSFQTKFDFTSCQGVLFVL :::.::..:...:: .::.:.: .:.. . :::.: .:::.: :::: ::::: :.. :: NP_001 LLTLFTFAMGFMTGTISSMYQTKAVIIAMIITAVVSISVTIFCFQTKVDFTSCTGLFCVL 170 180 190 200 210 220 240 250 260 270 280 290 pF1KA0 LMTLFFSGLILAILLPFQYVPWLHAVYAALGAGVFTLFLALDTQLLMGNRRHSLSPEEYI ..:. .:.. .:.: :::: ::: .:::::: :::::: ::::..:::.:..:::.:: NP_001 GIVLLVTGIVTSIVLYFQYVYWLHMLYAALGAICFTLFLAYDTQLVLGNRKHTISPEDYI 230 240 250 260 270 280 300 310 pF1KA0 FGALNIYLDIIYIFTFFLQLFGTNRE :::.:: :::::::: :::.: NP_001 TGALQIYTDIIYIFTFVLQLMGDRN 290 300 310 >>NP_071435 (OMIM: 610364) protein lifeguard 3 isoform 1 (311 aa) initn: 1023 init1: 935 opt: 984 Z-score: 888.5 bits: 172.6 E(85289): 9.5e-43 Smith-Waterman score: 987; 52.0% identity (74.0% similar) in 300 aa overlap (13-312:23-308) 10 20 30 40 50 pF1KA0 MTQGKLSVANKAPGTEGQQQVHGEKKEAPAVPSAPPSYEEATSGEGMKAG :: :: .: :. : :.: . : : :: NP_071 MSNPSAPPPYEDRNPLYPGPPPPGGYGQPSV------LPGGYPAYPGYPQP--GYGHPAG 10 20 30 40 50 60 70 80 90 100 110 pF1KA0 AFPPAPTAVPLHPSWAYVDPSSSSSYDNGFPTGDHELFTTFSWDDQKVRRVFVRKVYTIL : : : :: :. .:: : . . : :::.:::..:.::::.:. NP_071 YPQPMP---PTHPMPMNYGPGH--GYD-GEERAVSDSFGPGEWDDRKVRHTFIRKVYSII 60 70 80 90 100 120 130 140 150 160 170 pF1KA0 LIQLLVTLAVVALFTFCDPVKDYVQANPGWYWASYAVFFATYLTLACCSGPRRHFPWNLI .:::.:.:..:.::: .::. .:. : . :..::::: .::: ::::.::::.::::.: NP_071 SVQLLITVAIIAIFTFVEPVSAFVRRNVAVYYVSYAVFVVTYLILACCQGPRRRFPWNII 110 120 130 140 150 160 180 190 200 210 220 230 pF1KA0 LLTVFTLSMAYLTGMLSSYYNTTSVLLCLGITALVCLSVTVFSFQTKFDFTSCQGVLFVL :::.::..:...:: .::.:.: .:.. . :::.: .:::.: :::: ::::: :.. :: NP_071 LLTLFTFAMGFMTGTISSMYQTKAVIIAMIITAVVSISVTIFCFQTKVDFTSCTGLFCVL 170 180 190 200 210 220 240 250 260 270 280 290 pF1KA0 LMTLFFSGLILAILLPFQYVPWLHAVYAALGAGVFTLFLALDTQLLMGNRRHSLSPEEYI ..:. .:.. .:.: :::: ::: .:::::: :::::: ::::..:::.:..:::.:: NP_071 GIVLLVTGIVTSIVLYFQYVYWLHMLYAALGAICFTLFLAYDTQLVLGNRKHTISPEDYI 230 240 250 260 270 280 300 310 pF1KA0 FGALNIYLDIIYIFTFFLQLFGTNRE :::.:: :::::::: :::.: NP_071 TGALQIYTDIIYIFTFVLQLMGDRN 290 300 310 >>NP_001308364 (OMIM: 610364) protein lifeguard 3 isofor (311 aa) initn: 1023 init1: 935 opt: 984 Z-score: 888.5 bits: 172.6 E(85289): 9.5e-43 Smith-Waterman score: 987; 52.0% identity (74.0% similar) in 300 aa overlap (13-312:23-308) 10 20 30 40 50 pF1KA0 MTQGKLSVANKAPGTEGQQQVHGEKKEAPAVPSAPPSYEEATSGEGMKAG :: :: .: :. : :.: . : : :: NP_001 MSNPSAPPPYEDRNPLYPGPPPPGGYGQPSV------LPGGYPAYPGYPQP--GYGHPAG 10 20 30 40 50 60 70 80 90 100 110 pF1KA0 AFPPAPTAVPLHPSWAYVDPSSSSSYDNGFPTGDHELFTTFSWDDQKVRRVFVRKVYTIL : : : :: :. .:: : . . : :::.:::..:.::::.:. NP_001 YPQPMP---PTHPMPMNYGPGH--GYD-GEERAVSDSFGPGEWDDRKVRHTFIRKVYSII 60 70 80 90 100 120 130 140 150 160 170 pF1KA0 LIQLLVTLAVVALFTFCDPVKDYVQANPGWYWASYAVFFATYLTLACCSGPRRHFPWNLI .:::.:.:..:.::: .::. .:. : . :..::::: .::: ::::.::::.::::.: NP_001 SVQLLITVAIIAIFTFVEPVSAFVRRNVAVYYVSYAVFVVTYLILACCQGPRRRFPWNII 110 120 130 140 150 160 180 190 200 210 220 230 pF1KA0 LLTVFTLSMAYLTGMLSSYYNTTSVLLCLGITALVCLSVTVFSFQTKFDFTSCQGVLFVL :::.::..:...:: .::.:.: .:.. . :::.: .:::.: :::: ::::: :.. :: NP_001 LLTLFTFAMGFMTGTISSMYQTKAVIIAMIITAVVSISVTIFCFQTKVDFTSCTGLFCVL 170 180 190 200 210 220 240 250 260 270 280 290 pF1KA0 LMTLFFSGLILAILLPFQYVPWLHAVYAALGAGVFTLFLALDTQLLMGNRRHSLSPEEYI ..:. .:.. .:.: :::: ::: .:::::: :::::: ::::..:::.:..:::.:: NP_001 GIVLLVTGIVTSIVLYFQYVYWLHMLYAALGAICFTLFLAYDTQLVLGNRKHTISPEDYI 230 240 250 260 270 280 300 310 pF1KA0 FGALNIYLDIIYIFTFFLQLFGTNRE :::.:: :::::::: :::.: NP_001 TGALQIYTDIIYIFTFVLQLMGDRN 290 300 310 >>NP_001308358 (OMIM: 610364) protein lifeguard 3 isofor (311 aa) initn: 1023 init1: 935 opt: 984 Z-score: 888.5 bits: 172.6 E(85289): 9.5e-43 Smith-Waterman score: 987; 52.0% identity (74.0% similar) in 300 aa overlap (13-312:23-308) 10 20 30 40 50 pF1KA0 MTQGKLSVANKAPGTEGQQQVHGEKKEAPAVPSAPPSYEEATSGEGMKAG :: :: .: :. : :.: . : : :: NP_001 MSNPSAPPPYEDRNPLYPGPPPPGGYGQPSV------LPGGYPAYPGYPQP--GYGHPAG 10 20 30 40 50 60 70 80 90 100 110 pF1KA0 AFPPAPTAVPLHPSWAYVDPSSSSSYDNGFPTGDHELFTTFSWDDQKVRRVFVRKVYTIL : : : :: :. .:: : . . : :::.:::..:.::::.:. NP_001 YPQPMP---PTHPMPMNYGPGH--GYD-GEERAVSDSFGPGEWDDRKVRHTFIRKVYSII 60 70 80 90 100 120 130 140 150 160 170 pF1KA0 LIQLLVTLAVVALFTFCDPVKDYVQANPGWYWASYAVFFATYLTLACCSGPRRHFPWNLI .:::.:.:..:.::: .::. .:. : . :..::::: .::: ::::.::::.::::.: NP_001 SVQLLITVAIIAIFTFVEPVSAFVRRNVAVYYVSYAVFVVTYLILACCQGPRRRFPWNII 110 120 130 140 150 160 180 190 200 210 220 230 pF1KA0 LLTVFTLSMAYLTGMLSSYYNTTSVLLCLGITALVCLSVTVFSFQTKFDFTSCQGVLFVL :::.::..:...:: .::.:.: .:.. . :::.: .:::.: :::: ::::: :.. :: NP_001 LLTLFTFAMGFMTGTISSMYQTKAVIIAMIITAVVSISVTIFCFQTKVDFTSCTGLFCVL 170 180 190 200 210 220 240 250 260 270 280 290 pF1KA0 LMTLFFSGLILAILLPFQYVPWLHAVYAALGAGVFTLFLALDTQLLMGNRRHSLSPEEYI ..:. .:.. .:.: :::: ::: .:::::: :::::: ::::..:::.:..:::.:: NP_001 GIVLLVTGIVTSIVLYFQYVYWLHMLYAALGAICFTLFLAYDTQLVLGNRKHTISPEDYI 230 240 250 260 270 280 300 310 pF1KA0 FGALNIYLDIIYIFTFFLQLFGTNRE :::.:: :::::::: :::.: NP_001 TGALQIYTDIIYIFTFVLQLMGDRN 290 300 310 316 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 01:12:01 2016 done: Fri Nov 4 01:12:02 2016 Total Scan time: 7.590 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]