FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0968, 478 aa 1>>>pF1KA0968 478 - 478 aa - 478 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.1260+/-0.00076; mu= -5.8593+/- 0.045 mean_var=629.0648+/-146.627, 0's: 0 Z-trim(113.5): 1720 B-trim: 481 in 1/48 Lambda= 0.051136 statistics sampled from 20582 (22895) to 20582 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.623), E-opt: 0.2 (0.268), width: 16 Scan time: 7.420 The best scores are: opt bits E(85289) NP_741960 (OMIM: 114078) calcium/calmodulin-depend ( 478) 3225 254.3 5.6e-67 XP_016865387 (OMIM: 114078) PREDICTED: calcium/cal ( 478) 3216 253.6 8.8e-67 XP_006714393 (OMIM: 607708) PREDICTED: calcium/cal ( 478) 2886 229.3 1.9e-59 NP_742125 (OMIM: 607708) calcium/calmodulin-depend ( 478) 2854 226.9 9.6e-59 NP_742126 (OMIM: 607708) calcium/calmodulin-depend ( 478) 2854 226.9 9.6e-59 NP_742113 (OMIM: 607708) calcium/calmodulin-depend ( 478) 2854 226.9 9.6e-59 NP_001212 (OMIM: 607708) calcium/calmodulin-depend ( 499) 2854 226.9 9.9e-59 XP_016864167 (OMIM: 607708) PREDICTED: calcium/cal ( 477) 2842 226.0 1.8e-58 NP_001308505 (OMIM: 607708) calcium/calmodulin-dep ( 477) 2842 226.0 1.8e-58 NP_001308503 (OMIM: 607708) calcium/calmodulin-dep ( 498) 2842 226.0 1.8e-58 NP_742080 (OMIM: 607707) calcium/calmodulin-depend ( 479) 2821 224.5 5.2e-58 NP_057065 (OMIM: 114078) calcium/calmodulin-depend ( 489) 2224 180.4 9.6e-45 XP_011530597 (OMIM: 607708) PREDICTED: calcium/cal ( 510) 2050 167.6 7.2e-41 NP_001308497 (OMIM: 607708) calcium/calmodulin-dep ( 503) 2049 167.6 7.5e-41 NP_001308504 (OMIM: 607708) calcium/calmodulin-dep ( 492) 2044 167.2 9.5e-41 NP_001308512 (OMIM: 607708) calcium/calmodulin-dep ( 492) 2044 167.2 9.5e-41 XP_016864161 (OMIM: 607708) PREDICTED: calcium/cal ( 513) 2044 167.2 9.7e-41 NP_001308501 (OMIM: 607708) calcium/calmodulin-dep ( 512) 2038 166.8 1.3e-40 NP_001308496 (OMIM: 607708) calcium/calmodulin-dep ( 512) 2038 166.8 1.3e-40 NP_001308500 (OMIM: 607708) calcium/calmodulin-dep ( 533) 2038 166.8 1.4e-40 XP_016864166 (OMIM: 607708) PREDICTED: calcium/cal ( 491) 2032 166.3 1.8e-40 NP_001308506 (OMIM: 607708) calcium/calmodulin-dep ( 491) 2032 166.3 1.8e-40 XP_016864162 (OMIM: 607708) PREDICTED: calcium/cal ( 512) 2032 166.3 1.8e-40 XP_016864163 (OMIM: 607708) PREDICTED: calcium/cal ( 511) 2026 165.9 2.4e-40 XP_005263311 (OMIM: 607708) PREDICTED: calcium/cal ( 532) 2026 165.9 2.5e-40 NP_001308511 (OMIM: 607708) calcium/calmodulin-dep ( 489) 2018 165.2 3.6e-40 XP_011530593 (OMIM: 607708) PREDICTED: calcium/cal ( 489) 2018 165.2 3.6e-40 NP_742127 (OMIM: 607708) calcium/calmodulin-depend ( 489) 2018 165.2 3.6e-40 XP_011530591 (OMIM: 607708) PREDICTED: calcium/cal ( 510) 2018 165.3 3.7e-40 NP_001308516 (OMIM: 607708) calcium/calmodulin-dep ( 503) 2017 165.2 3.8e-40 NP_001308520 (OMIM: 607708) calcium/calmodulin-dep ( 503) 2017 165.2 3.8e-40 NP_001308502 (OMIM: 607708) calcium/calmodulin-dep ( 524) 2017 165.2 3.9e-40 NP_001308519 (OMIM: 607708) calcium/calmodulin-dep ( 492) 2012 164.8 4.9e-40 NP_001308518 (OMIM: 607708) calcium/calmodulin-dep ( 492) 2012 164.8 4.9e-40 NP_742112 (OMIM: 607708) calcium/calmodulin-depend ( 492) 2012 164.8 4.9e-40 NP_001308495 (OMIM: 607708) calcium/calmodulin-dep ( 513) 2012 164.8 5e-40 NP_001308509 (OMIM: 607708) calcium/calmodulin-dep ( 519) 2010 164.7 5.6e-40 XP_011530592 (OMIM: 607708) PREDICTED: calcium/cal ( 509) 2006 164.4 6.8e-40 NP_001308508 (OMIM: 607708) calcium/calmodulin-dep ( 512) 2006 164.4 6.8e-40 NP_001308499 (OMIM: 607708) calcium/calmodulin-dep ( 512) 2006 164.4 6.8e-40 NP_001308498 (OMIM: 607708) calcium/calmodulin-dep ( 533) 2006 164.4 6.9e-40 NP_742078 (OMIM: 607707) calcium/calmodulin-depend ( 503) 2005 164.3 7.1e-40 NP_742076 (OMIM: 607707) calcium/calmodulin-depend ( 518) 2005 164.3 7.2e-40 XP_016868149 (OMIM: 607707) PREDICTED: calcium/cal ( 670) 2005 164.5 8.2e-40 XP_011513852 (OMIM: 607707) PREDICTED: calcium/cal ( 685) 2005 164.5 8.3e-40 NP_001308513 (OMIM: 607708) calcium/calmodulin-dep ( 491) 2000 163.9 9e-40 NP_001308517 (OMIM: 607708) calcium/calmodulin-dep ( 512) 2000 164.0 9.2e-40 XP_005249921 (OMIM: 607707) PREDICTED: calcium/cal ( 494) 1998 163.8 1e-39 XP_011513858 (OMIM: 607707) PREDICTED: calcium/cal ( 661) 1998 164.0 1.2e-39 NP_001308515 (OMIM: 607708) calcium/calmodulin-dep ( 511) 1994 163.5 1.3e-39 >>NP_741960 (OMIM: 114078) calcium/calmodulin-dependent (478 aa) initn: 3225 init1: 3225 opt: 3225 Z-score: 1323.5 bits: 254.3 E(85289): 5.6e-67 Smith-Waterman score: 3225; 100.0% identity (100.0% similar) in 478 aa overlap (1-478:1-478) 10 20 30 40 50 60 pF1KA0 MATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLERE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_741 MATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLERE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 ARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_741 ARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQIL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 EAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_741 EAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 SPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_741 SPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 TPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_741 TPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 GAILTTMLATRNFSGGKSGGNKKSDGVKESSESTNTTIEDEDTKVRKQEIIKVTEQLIEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_741 GAILTTMLATRNFSGGKSGGNKKSDGVKESSESTNTTIEDEDTKVRKQEIIKVTEQLIEA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 ISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_741 ISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHIH 370 380 390 400 410 420 430 440 450 460 470 pF1KA0 LMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHRSGAPSVLPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_741 LMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHRSGAPSVLPH 430 440 450 460 470 >>XP_016865387 (OMIM: 114078) PREDICTED: calcium/calmodu (478 aa) initn: 3216 init1: 3216 opt: 3216 Z-score: 1319.9 bits: 253.6 E(85289): 8.8e-67 Smith-Waterman score: 3216; 99.8% identity (100.0% similar) in 478 aa overlap (1-478:1-478) 10 20 30 40 50 60 pF1KA0 MATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLERE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLERE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 ARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQIL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 EAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 SPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 TPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 GAILTTMLATRNFSGGKSGGNKKSDGVKESSESTNTTIEDEDTKVRKQEIIKVTEQLIEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GAILTTMLATRNFSGGKSGGNKKSDGVKESSESTNTTIEDEDTKVRKQEIIKVTEQLIEA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 ISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHIH 370 380 390 400 410 420 430 440 450 460 470 pF1KA0 LMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHRSGAPSVLPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::. XP_016 LMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHRSGAPSVLPQ 430 440 450 460 470 >>XP_006714393 (OMIM: 607708) PREDICTED: calcium/calmodu (478 aa) initn: 2892 init1: 2015 opt: 2886 Z-score: 1188.3 bits: 229.3 E(85289): 1.9e-59 Smith-Waterman score: 2886; 88.6% identity (96.8% similar) in 474 aa overlap (2-475:3-475) 10 20 30 40 50 pF1KA0 MATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLER .: ::::::.:::::::::::::::::::.:. .:::::::::::::::::::::::: XP_006 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 10 20 30 40 50 60 60 70 80 90 100 110 pF1KA0 EARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQI :::::::::::::::::::::::: :::.::::::::::::::::::::::::::::::: XP_006 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 70 80 90 100 110 120 120 130 140 150 160 170 pF1KA0 LEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGY ::::::::::::::::::::::::::: ::::::::::::::::.:.::::::::::::: XP_006 LEAVLHCHQMGVVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 130 140 150 160 170 180 180 190 200 210 220 230 pF1KA0 LSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT ::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::: XP_006 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 190 200 210 220 230 240 240 250 260 270 280 290 pF1KA0 VTPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKL :::::::::::::::::.:::::.:::::::: .:::::: ::::::::::::::::::: XP_006 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 250 260 270 280 290 300 300 310 320 330 340 350 pF1KA0 KGAILTTMLATRNFSGGKSGGNKKSDGVKESSESTNTTIEDEDTKVRKQEIIKVTEQLIE :::::::::::::::..:: :: ::::::.::.::::::::.:.:::::::::::::: XP_006 KGAILTTMLATRNFSAAKSLL-KKPDGVKESTESSNTTIEDEDVKARKQEIIKVTEQLIE 310 320 330 340 350 360 370 380 390 400 410 pF1KA0 AISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHI ::.:::::.:::.::::.::::::::::::::.::::::::: :...::.:: :::::. XP_006 AINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHV 360 370 380 390 400 410 420 430 440 450 460 470 pF1KA0 HLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHRSGAPSVLPH ::.::..:::::::.:::.:..:.:.: :::::::::::::::: :::::::.:.: XP_006 HLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIK 420 430 440 450 460 470 >>NP_742125 (OMIM: 607708) calcium/calmodulin-dependent (478 aa) initn: 2860 init1: 1983 opt: 2854 Z-score: 1175.6 bits: 226.9 E(85289): 9.6e-59 Smith-Waterman score: 2854; 87.6% identity (96.2% similar) in 474 aa overlap (2-475:3-475) 10 20 30 40 50 pF1KA0 MATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLER .: ::::::.:::::::::::::::::::.:. .:::::::::::::::::::::::: NP_742 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 10 20 30 40 50 60 60 70 80 90 100 110 pF1KA0 EARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQI :::::::::::::::::::::::: :::.::::::::::::::::::::::::::::::: NP_742 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 70 80 90 100 110 120 120 130 140 150 160 170 pF1KA0 LEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGY ::.: ::: :.::::::::::::::: ::::::::::::::::.:.::::::::::::: NP_742 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 130 140 150 160 170 180 180 190 200 210 220 230 pF1KA0 LSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT ::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::: NP_742 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 190 200 210 220 230 240 240 250 260 270 280 290 pF1KA0 VTPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKL :::::::::::::::::.:::::.:::::::: .:::::: ::::::::::::::::::: NP_742 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 250 260 270 280 290 300 300 310 320 330 340 350 pF1KA0 KGAILTTMLATRNFSGGKSGGNKKSDGVKESSESTNTTIEDEDTKVRKQEIIKVTEQLIE :::::::::::::::..:: :: ::::::.::.::::::::.:.:::::::::::::: NP_742 KGAILTTMLATRNFSAAKSLL-KKPDGVKESTESSNTTIEDEDVKARKQEIIKVTEQLIE 310 320 330 340 350 360 370 380 390 400 410 pF1KA0 AISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHI ::.:::::.:::.::::.::::::::::::::.::::::::: :...::.:: :::::. NP_742 AINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHV 360 370 380 390 400 410 420 430 440 450 460 470 pF1KA0 HLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHRSGAPSVLPH ::.::..:::::::.:::.:..:.:.: :::::::::::::::: :::::::.:.: NP_742 HLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIK 420 430 440 450 460 470 >>NP_742126 (OMIM: 607708) calcium/calmodulin-dependent (478 aa) initn: 2860 init1: 1983 opt: 2854 Z-score: 1175.6 bits: 226.9 E(85289): 9.6e-59 Smith-Waterman score: 2854; 87.6% identity (96.2% similar) in 474 aa overlap (2-475:3-475) 10 20 30 40 50 pF1KA0 MATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLER .: ::::::.:::::::::::::::::::.:. .:::::::::::::::::::::::: NP_742 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 10 20 30 40 50 60 60 70 80 90 100 110 pF1KA0 EARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQI :::::::::::::::::::::::: :::.::::::::::::::::::::::::::::::: NP_742 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 70 80 90 100 110 120 120 130 140 150 160 170 pF1KA0 LEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGY ::.: ::: :.::::::::::::::: ::::::::::::::::.:.::::::::::::: NP_742 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 130 140 150 160 170 180 180 190 200 210 220 230 pF1KA0 LSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT ::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::: NP_742 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 190 200 210 220 230 240 240 250 260 270 280 290 pF1KA0 VTPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKL :::::::::::::::::.:::::.:::::::: .:::::: ::::::::::::::::::: NP_742 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 250 260 270 280 290 300 300 310 320 330 340 350 pF1KA0 KGAILTTMLATRNFSGGKSGGNKKSDGVKESSESTNTTIEDEDTKVRKQEIIKVTEQLIE :::::::::::::::..:: :: ::::::.::.::::::::.:.:::::::::::::: NP_742 KGAILTTMLATRNFSAAKSLL-KKPDGVKESTESSNTTIEDEDVKARKQEIIKVTEQLIE 310 320 330 340 350 360 370 380 390 400 410 pF1KA0 AISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHI ::.:::::.:::.::::.::::::::::::::.::::::::: :...::.:: :::::. NP_742 AINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHV 360 370 380 390 400 410 420 430 440 450 460 470 pF1KA0 HLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHRSGAPSVLPH ::.::..:::::::.:::.:..:.:.: :::::::::::::::: :::::::.:.: NP_742 HLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIN 420 430 440 450 460 470 >>NP_742113 (OMIM: 607708) calcium/calmodulin-dependent (478 aa) initn: 2860 init1: 1983 opt: 2854 Z-score: 1175.6 bits: 226.9 E(85289): 9.6e-59 Smith-Waterman score: 2854; 87.6% identity (96.2% similar) in 474 aa overlap (2-475:3-475) 10 20 30 40 50 pF1KA0 MATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLER .: ::::::.:::::::::::::::::::.:. .:::::::::::::::::::::::: NP_742 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 10 20 30 40 50 60 60 70 80 90 100 110 pF1KA0 EARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQI :::::::::::::::::::::::: :::.::::::::::::::::::::::::::::::: NP_742 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 70 80 90 100 110 120 120 130 140 150 160 170 pF1KA0 LEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGY ::.: ::: :.::::::::::::::: ::::::::::::::::.:.::::::::::::: NP_742 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 130 140 150 160 170 180 180 190 200 210 220 230 pF1KA0 LSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT ::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::: NP_742 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 190 200 210 220 230 240 240 250 260 270 280 290 pF1KA0 VTPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKL :::::::::::::::::.:::::.:::::::: .:::::: ::::::::::::::::::: NP_742 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 250 260 270 280 290 300 300 310 320 330 340 350 pF1KA0 KGAILTTMLATRNFSGGKSGGNKKSDGVKESSESTNTTIEDEDTKVRKQEIIKVTEQLIE :::::::::::::::..:: :: ::::::.::.::::::::.:.:::::::::::::: NP_742 KGAILTTMLATRNFSAAKSLL-KKPDGVKESTESSNTTIEDEDVKARKQEIIKVTEQLIE 310 320 330 340 350 360 370 380 390 400 410 pF1KA0 AISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHI ::.:::::.:::.::::.::::::::::::::.::::::::: :...::.:: :::::. NP_742 AINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHV 360 370 380 390 400 410 420 430 440 450 460 470 pF1KA0 HLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHRSGAPSVLPH ::.::..:::::::.:::.:..:.:.: :::::::::::::::: :::::::.:.: NP_742 HLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIK 420 430 440 450 460 470 >>NP_001212 (OMIM: 607708) calcium/calmodulin-dependent (499 aa) initn: 2860 init1: 1983 opt: 2854 Z-score: 1175.4 bits: 226.9 E(85289): 9.9e-59 Smith-Waterman score: 2854; 87.6% identity (96.2% similar) in 474 aa overlap (2-475:3-475) 10 20 30 40 50 pF1KA0 MATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLER .: ::::::.:::::::::::::::::::.:. .:::::::::::::::::::::::: NP_001 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 10 20 30 40 50 60 60 70 80 90 100 110 pF1KA0 EARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQI :::::::::::::::::::::::: :::.::::::::::::::::::::::::::::::: NP_001 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 70 80 90 100 110 120 120 130 140 150 160 170 pF1KA0 LEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGY ::.: ::: :.::::::::::::::: ::::::::::::::::.:.::::::::::::: NP_001 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 130 140 150 160 170 180 180 190 200 210 220 230 pF1KA0 LSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT ::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::: NP_001 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 190 200 210 220 230 240 240 250 260 270 280 290 pF1KA0 VTPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKL :::::::::::::::::.:::::.:::::::: .:::::: ::::::::::::::::::: NP_001 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 250 260 270 280 290 300 300 310 320 330 340 350 pF1KA0 KGAILTTMLATRNFSGGKSGGNKKSDGVKESSESTNTTIEDEDTKVRKQEIIKVTEQLIE :::::::::::::::..:: :: ::::::.::.::::::::.:.:::::::::::::: NP_001 KGAILTTMLATRNFSAAKSLL-KKPDGVKESTESSNTTIEDEDVKARKQEIIKVTEQLIE 310 320 330 340 350 360 370 380 390 400 410 pF1KA0 AISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHI ::.:::::.:::.::::.::::::::::::::.::::::::: :...::.:: :::::. NP_001 AINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHV 360 370 380 390 400 410 420 430 440 450 460 470 pF1KA0 HLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHRSGAPSVLPH ::.::..:::::::.:::.:..:.:.: :::::::::::::::: :::::::.:.: NP_001 HLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIKP 420 430 440 450 460 470 NP_001 PCIPNGKENFSGGTSLWQNI 480 490 >>XP_016864167 (OMIM: 607708) PREDICTED: calcium/calmodu (477 aa) initn: 2849 init1: 1972 opt: 2842 Z-score: 1170.8 bits: 226.0 E(85289): 1.8e-58 Smith-Waterman score: 2842; 87.6% identity (96.0% similar) in 474 aa overlap (2-475:3-474) 10 20 30 40 50 pF1KA0 MATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLER .: ::::::.:::::::::::::::::::.:. .:::::::::::::::::::::::: XP_016 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 10 20 30 40 50 60 60 70 80 90 100 110 pF1KA0 EARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQI :::::::::::::::::::::::: :::.::::::::::::::::::::::::::::::: XP_016 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 70 80 90 100 110 120 120 130 140 150 160 170 pF1KA0 LEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGY ::.: ::: :.::::::::::::::: ::::::::::::::::.:.::::::::::::: XP_016 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 130 140 150 160 170 180 180 190 200 210 220 230 pF1KA0 LSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT ::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::: XP_016 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 190 200 210 220 230 240 240 250 260 270 280 290 pF1KA0 VTPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKL :::::::::::::::::.:::::.:::::::: .:::::: ::::::::::::::::::: XP_016 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 250 260 270 280 290 300 300 310 320 330 340 350 pF1KA0 KGAILTTMLATRNFSGGKSGGNKKSDGVKESSESTNTTIEDEDTKVRKQEIIKVTEQLIE :::::::::::::::. :: :: ::::::.::.::::::::.:.:::::::::::::: XP_016 KGAILTTMLATRNFSA-KSLL-KKPDGVKESTESSNTTIEDEDVKARKQEIIKVTEQLIE 310 320 330 340 350 360 370 380 390 400 410 pF1KA0 AISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHI ::.:::::.:::.::::.::::::::::::::.::::::::: :...::.:: :::::. XP_016 AINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHV 360 370 380 390 400 410 420 430 440 450 460 470 pF1KA0 HLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHRSGAPSVLPH ::.::..:::::::.:::.:..:.:.: :::::::::::::::: :::::::.:.: XP_016 HLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIK 420 430 440 450 460 470 >>NP_001308505 (OMIM: 607708) calcium/calmodulin-depende (477 aa) initn: 2849 init1: 1972 opt: 2842 Z-score: 1170.8 bits: 226.0 E(85289): 1.8e-58 Smith-Waterman score: 2842; 87.6% identity (96.0% similar) in 474 aa overlap (2-475:3-474) 10 20 30 40 50 pF1KA0 MATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLER .: ::::::.:::::::::::::::::::.:. .:::::::::::::::::::::::: NP_001 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 10 20 30 40 50 60 60 70 80 90 100 110 pF1KA0 EARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQI :::::::::::::::::::::::: :::.::::::::::::::::::::::::::::::: NP_001 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 70 80 90 100 110 120 120 130 140 150 160 170 pF1KA0 LEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGY ::.: ::: :.::::::::::::::: ::::::::::::::::.:.::::::::::::: NP_001 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 130 140 150 160 170 180 180 190 200 210 220 230 pF1KA0 LSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT ::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::: NP_001 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 190 200 210 220 230 240 240 250 260 270 280 290 pF1KA0 VTPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKL :::::::::::::::::.:::::.:::::::: .:::::: ::::::::::::::::::: NP_001 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 250 260 270 280 290 300 300 310 320 330 340 350 pF1KA0 KGAILTTMLATRNFSGGKSGGNKKSDGVKESSESTNTTIEDEDTKVRKQEIIKVTEQLIE :::::::::::::::. :: :: ::::::.::.::::::::.:.:::::::::::::: NP_001 KGAILTTMLATRNFSA-KSLL-KKPDGVKESTESSNTTIEDEDVKARKQEIIKVTEQLIE 310 320 330 340 350 360 370 380 390 400 410 pF1KA0 AISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHI ::.:::::.:::.::::.::::::::::::::.::::::::: :...::.:: :::::. NP_001 AINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHV 360 370 380 390 400 410 420 430 440 450 460 470 pF1KA0 HLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHRSGAPSVLPH ::.::..:::::::.:::.:..:.:.: :::::::::::::::: :::::::.:.: NP_001 HLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIN 420 430 440 450 460 470 >>NP_001308503 (OMIM: 607708) calcium/calmodulin-depende (498 aa) initn: 2849 init1: 1972 opt: 2842 Z-score: 1170.6 bits: 226.0 E(85289): 1.8e-58 Smith-Waterman score: 2842; 87.6% identity (96.0% similar) in 474 aa overlap (2-475:3-474) 10 20 30 40 50 pF1KA0 MATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLER .: ::::::.:::::::::::::::::::.:. .:::::::::::::::::::::::: NP_001 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 10 20 30 40 50 60 60 70 80 90 100 110 pF1KA0 EARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQI :::::::::::::::::::::::: :::.::::::::::::::::::::::::::::::: NP_001 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 70 80 90 100 110 120 120 130 140 150 160 170 pF1KA0 LEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGY ::.: ::: :.::::::::::::::: ::::::::::::::::.:.::::::::::::: NP_001 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 130 140 150 160 170 180 180 190 200 210 220 230 pF1KA0 LSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT ::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::: NP_001 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 190 200 210 220 230 240 240 250 260 270 280 290 pF1KA0 VTPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKL :::::::::::::::::.:::::.:::::::: .:::::: ::::::::::::::::::: NP_001 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 250 260 270 280 290 300 300 310 320 330 340 350 pF1KA0 KGAILTTMLATRNFSGGKSGGNKKSDGVKESSESTNTTIEDEDTKVRKQEIIKVTEQLIE :::::::::::::::. :: :: ::::::.::.::::::::.:.:::::::::::::: NP_001 KGAILTTMLATRNFSA-KSLL-KKPDGVKESTESSNTTIEDEDVKARKQEIIKVTEQLIE 310 320 330 340 350 360 370 380 390 400 410 pF1KA0 AISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHI ::.:::::.:::.::::.::::::::::::::.::::::::: :...::.:: :::::. NP_001 AINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHV 360 370 380 390 400 410 420 430 440 450 460 470 pF1KA0 HLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHRSGAPSVLPH ::.::..:::::::.:::.:..:.:.: :::::::::::::::: :::::::.:.: NP_001 HLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIKP 420 430 440 450 460 470 NP_001 PCIPNGKENFSGGTSLWQNI 480 490 478 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 20:09:08 2016 done: Wed Nov 2 20:09:09 2016 Total Scan time: 7.420 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]