FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0970, 1142 aa 1>>>pF1KA0970 1142 - 1142 aa - 1142 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.0828+/-0.000434; mu= -1.3958+/- 0.027 mean_var=285.7875+/-60.449, 0's: 0 Z-trim(119.1): 242 B-trim: 33 in 1/56 Lambda= 0.075867 statistics sampled from 32332 (32668) to 32332 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.702), E-opt: 0.2 (0.383), width: 16 Scan time: 14.660 The best scores are: opt bits E(85289) NP_055738 (OMIM: 615794) fibronectin type-III doma (1142) 7847 873.8 0 NP_001073141 (OMIM: 615794) fibronectin type-III d (1198) 7839 872.9 0 NP_001265367 (OMIM: 615794) fibronectin type-III d (1198) 7839 872.9 0 XP_016875929 (OMIM: 615794) PREDICTED: fibronectin (1198) 7839 872.9 0 XP_011533299 (OMIM: 615794) PREDICTED: fibronectin (1134) 7790 867.6 0 XP_016875931 (OMIM: 615794) PREDICTED: fibronectin (1134) 7790 867.6 0 XP_016875930 (OMIM: 615794) PREDICTED: fibronectin (1134) 7790 867.6 0 XP_016875932 (OMIM: 615794) PREDICTED: fibronectin (1041) 6478 723.9 1.2e-207 NP_073600 (OMIM: 611909) fibronectin type III doma (1204) 3963 448.7 1e-124 NP_001128567 (OMIM: 611909) fibronectin type III d (1204) 3963 448.7 1e-124 XP_016862552 (OMIM: 611909) PREDICTED: fibronectin ( 956) 3506 398.6 9.5e-110 XP_016862551 (OMIM: 611909) PREDICTED: fibronectin (1110) 3506 398.6 1.1e-109 XP_016862553 (OMIM: 611909) PREDICTED: fibronectin ( 674) 1981 231.6 1.3e-59 NP_996816 (OMIM: 276901,608400,613809) usherin iso (5202) 498 69.9 4.5e-10 XP_005271139 (OMIM: 179590,616001) PREDICTED: rece (1796) 478 67.4 9.1e-10 XP_016857433 (OMIM: 179590,616001) PREDICTED: rece (1800) 478 67.4 9.1e-10 XP_016857434 (OMIM: 179590,616001) PREDICTED: rece (1807) 478 67.4 9.1e-10 XP_006710863 (OMIM: 179590,616001) PREDICTED: rece (1811) 478 67.4 9.1e-10 NP_003310 (OMIM: 188840,600334,603689,604145,60880 (26926) 505 71.3 9.3e-10 XP_016860312 (OMIM: 188840,600334,603689,604145,60 (26973) 505 71.3 9.3e-10 NP_597676 (OMIM: 188840,600334,603689,604145,60880 (27051) 505 71.3 9.3e-10 NP_597681 (OMIM: 188840,600334,603689,604145,60880 (27118) 505 71.3 9.3e-10 XP_016860311 (OMIM: 188840,600334,603689,604145,60 (33101) 505 71.3 1.1e-09 NP_596869 (OMIM: 188840,600334,603689,604145,60880 (33423) 505 71.3 1.1e-09 XP_016860310 (OMIM: 188840,600334,603689,604145,60 (34087) 505 71.3 1.1e-09 XP_016860309 (OMIM: 188840,600334,603689,604145,60 (34088) 505 71.3 1.1e-09 NP_001243779 (OMIM: 188840,600334,603689,604145,60 (34350) 505 71.3 1.1e-09 XP_016860308 (OMIM: 188840,600334,603689,604145,60 (35622) 505 71.4 1.1e-09 NP_001254479 (OMIM: 188840,600334,603689,604145,60 (35991) 505 71.4 1.2e-09 XP_006710864 (OMIM: 179590,616001) PREDICTED: rece (1729) 415 60.5 1e-07 NP_569707 (OMIM: 179590,616001) receptor-type tyro (1898) 407 59.6 2.1e-07 XP_006710861 (OMIM: 179590,616001) PREDICTED: rece (1902) 407 59.6 2.1e-07 NP_002831 (OMIM: 179590,616001) receptor-type tyro (1907) 407 59.6 2.1e-07 XP_005271138 (OMIM: 179590,616001) PREDICTED: rece (1909) 407 59.6 2.1e-07 XP_006710860 (OMIM: 179590,616001) PREDICTED: rece (1911) 407 59.6 2.1e-07 XP_016857431 (OMIM: 179590,616001) PREDICTED: rece (1912) 407 59.6 2.1e-07 XP_006710859 (OMIM: 179590,616001) PREDICTED: rece (1913) 407 59.6 2.1e-07 XP_005271137 (OMIM: 179590,616001) PREDICTED: rece (1918) 407 59.6 2.1e-07 XP_006710858 (OMIM: 179590,616001) PREDICTED: rece (1922) 407 59.6 2.1e-07 XP_011540175 (OMIM: 179590,616001) PREDICTED: rece (1922) 407 59.6 2.1e-07 XP_005271136 (OMIM: 179590,616001) PREDICTED: rece (1922) 407 59.6 2.1e-07 XP_011540173 (OMIM: 179590,616001) PREDICTED: rece (1922) 407 59.6 2.1e-07 XP_011540174 (OMIM: 179590,616001) PREDICTED: rece (1922) 407 59.6 2.1e-07 XP_016874764 (OMIM: 603317,613391) PREDICTED: phos (2145) 394 58.3 6.1e-07 NP_001138498 (OMIM: 603317,613391) phosphatidylino (2299) 394 58.3 6.4e-07 XP_016874763 (OMIM: 603317,613391) PREDICTED: phos (2533) 394 58.3 6.9e-07 XP_016874762 (OMIM: 603317,613391) PREDICTED: phos (2536) 394 58.3 6.9e-07 NP_001316069 (OMIM: 179590,616001) receptor-type t (1603) 376 56.2 1.9e-06 XP_016857436 (OMIM: 179590,616001) PREDICTED: rece (1618) 376 56.2 1.9e-06 XP_005259664 (OMIM: 601576) PREDICTED: receptor-ty (1906) 367 55.3 4.3e-06 >>NP_055738 (OMIM: 615794) fibronectin type-III domain-c (1142 aa) initn: 7847 init1: 7847 opt: 7847 Z-score: 4658.1 bits: 873.8 E(85289): 0 Smith-Waterman score: 7847; 100.0% identity (100.0% similar) in 1142 aa overlap (1-1142:1-1142) 10 20 30 40 50 60 pF1KA0 MSGPAQVPMMSPNGSVPPIYVPPGYAPQVIEDNGVRRVVVVPQAPEFHPGSHTVLHRSPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MSGPAQVPMMSPNGSVPPIYVPPGYAPQVIEDNGVRRVVVVPQAPEFHPGSHTVLHRSPH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 PPLPGFIPVPTMMPPPPRHMYSPVTGAGDMTTQYMPQYQSSQVYGDVDAHSTHGRSNFRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PPLPGFIPVPTMMPPPPRHMYSPVTGAGDMTTQYMPQYQSSQVYGDVDAHSTHGRSNFRD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 ERSSKTYERLQKKLKDRQGTQKDKMSSPPSSPQKCPSPINEHNGLIKGQIAGGINTGSAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ERSSKTYERLQKKLKDRQGTQKDKMSSPPSSPQKCPSPINEHNGLIKGQIAGGINTGSAK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 IKSGKGKGGTQVDTEIEEKDEETKAFEALLSNIVKPVASDIQARTVVLTWSPPSSLINGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 IKSGKGKGGTQVDTEIEEKDEETKAFEALLSNIVKPVASDIQARTVVLTWSPPSSLINGE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 TDESSVPELYGYEVLISSTGKDGKYKSVYVGEETNITLNDLKPAMDYHAKVQAEYNSIKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TDESSVPELYGYEVLISSTGKDGKYKSVYVGEETNITLNDLKPAMDYHAKVQAEYNSIKG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 TPSEAEIFTTLSCEPDIPNPPRIANRTKNSLTLQWKAPSDNGSKIQNFVLEWDEGKGNGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TPSEAEIFTTLSCEPDIPNPPRIANRTKNSLTLQWKAPSDNGSKIQNFVLEWDEGKGNGE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 FCQCYMGSQKQFKITKLSPAMGCKFRLSARNDYGTSGFSEEVLYYTSGCAPSMPASPVLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 FCQCYMGSQKQFKITKLSPAMGCKFRLSARNDYGTSGFSEEVLYYTSGCAPSMPASPVLT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 KAGITWLSLQWSKPSGTPSDEGISYILEMEEETSGYGFKPKYDGEDLAYTVKNLRRSTKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KAGITWLSLQWSKPSGTPSDEGISYILEMEEETSGYGFKPKYDGEDLAYTVKNLRRSTKY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 KFKVIAYNSEGKSNPSEVVEFTTCPDKPGIPVKPSVKGKIHSHSFKITWDPPKDNGGATI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KFKVIAYNSEGKSNPSEVVEFTTCPDKPGIPVKPSVKGKIHSHSFKITWDPPKDNGGATI 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 NKYVVEMAEGSNGNKWEMIYSGATREHLCDRLNPGCFYRLRVYCISDGGQSAVSESLLVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 NKYVVEMAEGSNGNKWEMIYSGATREHLCDRLNPGCFYRLRVYCISDGGQSAVSESLLVQ 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 TPAVPPGPCLPPRLQGRPKAKEIQLRWGPPLVDGGSPISCYSVEMSPIEKDEPREVYQGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TPAVPPGPCLPPRLQGRPKAKEIQLRWGPPLVDGGSPISCYSVEMSPIEKDEPREVYQGS 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA0 EVECTVSSLLPGKTYSFRLRAANKMGFGPFSEKCDITTAPGPPDQCKPPQVTCRSATCAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EVECTVSSLLPGKTYSFRLRAANKMGFGPFSEKCDITTAPGPPDQCKPPQVTCRSATCAQ 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA0 VNWEVPLSNGTDVTEYRLEWGGVEGSMQICYCGPGLSYEIKGLSPATTYYCRVQALSVVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VNWEVPLSNGTDVTEYRLEWGGVEGSMQICYCGPGLSYEIKGLSPATTYYCRVQALSVVG 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA0 AGPFSEVVACVTPPSVPGIVTCLQEISDDEIENPHYSPSTCLAISWEKPCDHGSEILAYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 AGPFSEVVACVTPPSVPGIVTCLQEISDDEIENPHYSPSTCLAISWEKPCDHGSEILAYS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA0 IDFGDKQSLTVGKVTSYIINNLQPDTTYRIRIQALNSLGAGPFSHMIKLKTKPLPPDPPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 IDFGDKQSLTVGKVTSYIINNLQPDTTYRIRIQALNSLGAGPFSHMIKLKTKPLPPDPPR 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA0 LECVAFSHQNLKLKWGEGTPKTLSTDSIQYHLQMEDKNGRFVSLYRGPCHTYKVQRLNES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LECVAFSHQNLKLKWGEGTPKTLSTDSIQYHLQMEDKNGRFVSLYRGPCHTYKVQRLNES 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA0 TSYKFCIQACNEAGEGPLSQEYIFTTPKSVPAALKAPKIEKVNDHICEITWECLQPMKGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TSYKFCIQACNEAGEGPLSQEYIFTTPKSVPAALKAPKIEKVNDHICEITWECLQPMKGD 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA0 PVIYSLQVMLGKDSEFKQIYKGPDSSFRYSSLQLNCEYRFRVCAIRQCQDSLGHQDLVGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PVIYSLQVMLGKDSEFKQIYKGPDSSFRYSSLQLNCEYRFRVCAIRQCQDSLGHQDLVGP 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA0 YSTTVLFISQRTEPPASTNRDTVESTRTRRALSDEQCAAVILVLFAFFSILIAFIIQYFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 YSTTVLFISQRTEPPASTNRDTVESTRTRRALSDEQCAAVILVLFAFFSILIAFIIQYFV 1090 1100 1110 1120 1130 1140 pF1KA0 IK :: NP_055 IK >>NP_001073141 (OMIM: 615794) fibronectin type-III domai (1198 aa) initn: 7839 init1: 7839 opt: 7839 Z-score: 4653.1 bits: 872.9 E(85289): 0 Smith-Waterman score: 7839; 99.8% identity (100.0% similar) in 1142 aa overlap (1-1142:57-1198) 10 20 30 pF1KA0 MSGPAQVPMMSPNGSVPPIYVPPGYAPQVI ..:::::::::::::::::::::::::::: NP_001 SADGTQQVILVQVNPGEAFTIRREDGQFQCITGPAQVPMMSPNGSVPPIYVPPGYAPQVI 30 40 50 60 70 80 40 50 60 70 80 90 pF1KA0 EDNGVRRVVVVPQAPEFHPGSHTVLHRSPHPPLPGFIPVPTMMPPPPRHMYSPVTGAGDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDNGVRRVVVVPQAPEFHPGSHTVLHRSPHPPLPGFIPVPTMMPPPPRHMYSPVTGAGDM 90 100 110 120 130 140 100 110 120 130 140 150 pF1KA0 TTQYMPQYQSSQVYGDVDAHSTHGRSNFRDERSSKTYERLQKKLKDRQGTQKDKMSSPPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TTQYMPQYQSSQVYGDVDAHSTHGRSNFRDERSSKTYERLQKKLKDRQGTQKDKMSSPPS 150 160 170 180 190 200 160 170 180 190 200 210 pF1KA0 SPQKCPSPINEHNGLIKGQIAGGINTGSAKIKSGKGKGGTQVDTEIEEKDEETKAFEALL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPQKCPSPINEHNGLIKGQIAGGINTGSAKIKSGKGKGGTQVDTEIEEKDEETKAFEALL 210 220 230 240 250 260 220 230 240 250 260 270 pF1KA0 SNIVKPVASDIQARTVVLTWSPPSSLINGETDESSVPELYGYEVLISSTGKDGKYKSVYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SNIVKPVASDIQARTVVLTWSPPSSLINGETDESSVPELYGYEVLISSTGKDGKYKSVYV 270 280 290 300 310 320 280 290 300 310 320 330 pF1KA0 GEETNITLNDLKPAMDYHAKVQAEYNSIKGTPSEAEIFTTLSCEPDIPNPPRIANRTKNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GEETNITLNDLKPAMDYHAKVQAEYNSIKGTPSEAEIFTTLSCEPDIPNPPRIANRTKNS 330 340 350 360 370 380 340 350 360 370 380 390 pF1KA0 LTLQWKAPSDNGSKIQNFVLEWDEGKGNGEFCQCYMGSQKQFKITKLSPAMGCKFRLSAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LTLQWKAPSDNGSKIQNFVLEWDEGKGNGEFCQCYMGSQKQFKITKLSPAMGCKFRLSAR 390 400 410 420 430 440 400 410 420 430 440 450 pF1KA0 NDYGTSGFSEEVLYYTSGCAPSMPASPVLTKAGITWLSLQWSKPSGTPSDEGISYILEME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NDYGTSGFSEEVLYYTSGCAPSMPASPVLTKAGITWLSLQWSKPSGTPSDEGISYILEME 450 460 470 480 490 500 460 470 480 490 500 510 pF1KA0 EETSGYGFKPKYDGEDLAYTVKNLRRSTKYKFKVIAYNSEGKSNPSEVVEFTTCPDKPGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EETSGYGFKPKYDGEDLAYTVKNLRRSTKYKFKVIAYNSEGKSNPSEVVEFTTCPDKPGI 510 520 530 540 550 560 520 530 540 550 560 570 pF1KA0 PVKPSVKGKIHSHSFKITWDPPKDNGGATINKYVVEMAEGSNGNKWEMIYSGATREHLCD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PVKPSVKGKIHSHSFKITWDPPKDNGGATINKYVVEMAEGSNGNKWEMIYSGATREHLCD 570 580 590 600 610 620 580 590 600 610 620 630 pF1KA0 RLNPGCFYRLRVYCISDGGQSAVSESLLVQTPAVPPGPCLPPRLQGRPKAKEIQLRWGPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLNPGCFYRLRVYCISDGGQSAVSESLLVQTPAVPPGPCLPPRLQGRPKAKEIQLRWGPP 630 640 650 660 670 680 640 650 660 670 680 690 pF1KA0 LVDGGSPISCYSVEMSPIEKDEPREVYQGSEVECTVSSLLPGKTYSFRLRAANKMGFGPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LVDGGSPISCYSVEMSPIEKDEPREVYQGSEVECTVSSLLPGKTYSFRLRAANKMGFGPF 690 700 710 720 730 740 700 710 720 730 740 750 pF1KA0 SEKCDITTAPGPPDQCKPPQVTCRSATCAQVNWEVPLSNGTDVTEYRLEWGGVEGSMQIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SEKCDITTAPGPPDQCKPPQVTCRSATCAQVNWEVPLSNGTDVTEYRLEWGGVEGSMQIC 750 760 770 780 790 800 760 770 780 790 800 810 pF1KA0 YCGPGLSYEIKGLSPATTYYCRVQALSVVGAGPFSEVVACVTPPSVPGIVTCLQEISDDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YCGPGLSYEIKGLSPATTYYCRVQALSVVGAGPFSEVVACVTPPSVPGIVTCLQEISDDE 810 820 830 840 850 860 820 830 840 850 860 870 pF1KA0 IENPHYSPSTCLAISWEKPCDHGSEILAYSIDFGDKQSLTVGKVTSYIINNLQPDTTYRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IENPHYSPSTCLAISWEKPCDHGSEILAYSIDFGDKQSLTVGKVTSYIINNLQPDTTYRI 870 880 890 900 910 920 880 890 900 910 920 930 pF1KA0 RIQALNSLGAGPFSHMIKLKTKPLPPDPPRLECVAFSHQNLKLKWGEGTPKTLSTDSIQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RIQALNSLGAGPFSHMIKLKTKPLPPDPPRLECVAFSHQNLKLKWGEGTPKTLSTDSIQY 930 940 950 960 970 980 940 950 960 970 980 990 pF1KA0 HLQMEDKNGRFVSLYRGPCHTYKVQRLNESTSYKFCIQACNEAGEGPLSQEYIFTTPKSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HLQMEDKNGRFVSLYRGPCHTYKVQRLNESTSYKFCIQACNEAGEGPLSQEYIFTTPKSV 990 1000 1010 1020 1030 1040 1000 1010 1020 1030 1040 1050 pF1KA0 PAALKAPKIEKVNDHICEITWECLQPMKGDPVIYSLQVMLGKDSEFKQIYKGPDSSFRYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PAALKAPKIEKVNDHICEITWECLQPMKGDPVIYSLQVMLGKDSEFKQIYKGPDSSFRYS 1050 1060 1070 1080 1090 1100 1060 1070 1080 1090 1100 1110 pF1KA0 SLQLNCEYRFRVCAIRQCQDSLGHQDLVGPYSTTVLFISQRTEPPASTNRDTVESTRTRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLQLNCEYRFRVCAIRQCQDSLGHQDLVGPYSTTVLFISQRTEPPASTNRDTVESTRTRR 1110 1120 1130 1140 1150 1160 1120 1130 1140 pF1KA0 ALSDEQCAAVILVLFAFFSILIAFIIQYFVIK :::::::::::::::::::::::::::::::: NP_001 ALSDEQCAAVILVLFAFFSILIAFIIQYFVIK 1170 1180 1190 >>NP_001265367 (OMIM: 615794) fibronectin type-III domai (1198 aa) initn: 7839 init1: 7839 opt: 7839 Z-score: 4653.1 bits: 872.9 E(85289): 0 Smith-Waterman score: 7839; 99.8% identity (100.0% similar) in 1142 aa overlap (1-1142:57-1198) 10 20 30 pF1KA0 MSGPAQVPMMSPNGSVPPIYVPPGYAPQVI ..:::::::::::::::::::::::::::: NP_001 SADGTQQVILVQVNPGEAFTIRREDGQFQCITGPAQVPMMSPNGSVPPIYVPPGYAPQVI 30 40 50 60 70 80 40 50 60 70 80 90 pF1KA0 EDNGVRRVVVVPQAPEFHPGSHTVLHRSPHPPLPGFIPVPTMMPPPPRHMYSPVTGAGDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDNGVRRVVVVPQAPEFHPGSHTVLHRSPHPPLPGFIPVPTMMPPPPRHMYSPVTGAGDM 90 100 110 120 130 140 100 110 120 130 140 150 pF1KA0 TTQYMPQYQSSQVYGDVDAHSTHGRSNFRDERSSKTYERLQKKLKDRQGTQKDKMSSPPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TTQYMPQYQSSQVYGDVDAHSTHGRSNFRDERSSKTYERLQKKLKDRQGTQKDKMSSPPS 150 160 170 180 190 200 160 170 180 190 200 210 pF1KA0 SPQKCPSPINEHNGLIKGQIAGGINTGSAKIKSGKGKGGTQVDTEIEEKDEETKAFEALL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPQKCPSPINEHNGLIKGQIAGGINTGSAKIKSGKGKGGTQVDTEIEEKDEETKAFEALL 210 220 230 240 250 260 220 230 240 250 260 270 pF1KA0 SNIVKPVASDIQARTVVLTWSPPSSLINGETDESSVPELYGYEVLISSTGKDGKYKSVYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SNIVKPVASDIQARTVVLTWSPPSSLINGETDESSVPELYGYEVLISSTGKDGKYKSVYV 270 280 290 300 310 320 280 290 300 310 320 330 pF1KA0 GEETNITLNDLKPAMDYHAKVQAEYNSIKGTPSEAEIFTTLSCEPDIPNPPRIANRTKNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GEETNITLNDLKPAMDYHAKVQAEYNSIKGTPSEAEIFTTLSCEPDIPNPPRIANRTKNS 330 340 350 360 370 380 340 350 360 370 380 390 pF1KA0 LTLQWKAPSDNGSKIQNFVLEWDEGKGNGEFCQCYMGSQKQFKITKLSPAMGCKFRLSAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LTLQWKAPSDNGSKIQNFVLEWDEGKGNGEFCQCYMGSQKQFKITKLSPAMGCKFRLSAR 390 400 410 420 430 440 400 410 420 430 440 450 pF1KA0 NDYGTSGFSEEVLYYTSGCAPSMPASPVLTKAGITWLSLQWSKPSGTPSDEGISYILEME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NDYGTSGFSEEVLYYTSGCAPSMPASPVLTKAGITWLSLQWSKPSGTPSDEGISYILEME 450 460 470 480 490 500 460 470 480 490 500 510 pF1KA0 EETSGYGFKPKYDGEDLAYTVKNLRRSTKYKFKVIAYNSEGKSNPSEVVEFTTCPDKPGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EETSGYGFKPKYDGEDLAYTVKNLRRSTKYKFKVIAYNSEGKSNPSEVVEFTTCPDKPGI 510 520 530 540 550 560 520 530 540 550 560 570 pF1KA0 PVKPSVKGKIHSHSFKITWDPPKDNGGATINKYVVEMAEGSNGNKWEMIYSGATREHLCD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PVKPSVKGKIHSHSFKITWDPPKDNGGATINKYVVEMAEGSNGNKWEMIYSGATREHLCD 570 580 590 600 610 620 580 590 600 610 620 630 pF1KA0 RLNPGCFYRLRVYCISDGGQSAVSESLLVQTPAVPPGPCLPPRLQGRPKAKEIQLRWGPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLNPGCFYRLRVYCISDGGQSAVSESLLVQTPAVPPGPCLPPRLQGRPKAKEIQLRWGPP 630 640 650 660 670 680 640 650 660 670 680 690 pF1KA0 LVDGGSPISCYSVEMSPIEKDEPREVYQGSEVECTVSSLLPGKTYSFRLRAANKMGFGPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LVDGGSPISCYSVEMSPIEKDEPREVYQGSEVECTVSSLLPGKTYSFRLRAANKMGFGPF 690 700 710 720 730 740 700 710 720 730 740 750 pF1KA0 SEKCDITTAPGPPDQCKPPQVTCRSATCAQVNWEVPLSNGTDVTEYRLEWGGVEGSMQIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SEKCDITTAPGPPDQCKPPQVTCRSATCAQVNWEVPLSNGTDVTEYRLEWGGVEGSMQIC 750 760 770 780 790 800 760 770 780 790 800 810 pF1KA0 YCGPGLSYEIKGLSPATTYYCRVQALSVVGAGPFSEVVACVTPPSVPGIVTCLQEISDDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YCGPGLSYEIKGLSPATTYYCRVQALSVVGAGPFSEVVACVTPPSVPGIVTCLQEISDDE 810 820 830 840 850 860 820 830 840 850 860 870 pF1KA0 IENPHYSPSTCLAISWEKPCDHGSEILAYSIDFGDKQSLTVGKVTSYIINNLQPDTTYRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IENPHYSPSTCLAISWEKPCDHGSEILAYSIDFGDKQSLTVGKVTSYIINNLQPDTTYRI 870 880 890 900 910 920 880 890 900 910 920 930 pF1KA0 RIQALNSLGAGPFSHMIKLKTKPLPPDPPRLECVAFSHQNLKLKWGEGTPKTLSTDSIQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RIQALNSLGAGPFSHMIKLKTKPLPPDPPRLECVAFSHQNLKLKWGEGTPKTLSTDSIQY 930 940 950 960 970 980 940 950 960 970 980 990 pF1KA0 HLQMEDKNGRFVSLYRGPCHTYKVQRLNESTSYKFCIQACNEAGEGPLSQEYIFTTPKSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HLQMEDKNGRFVSLYRGPCHTYKVQRLNESTSYKFCIQACNEAGEGPLSQEYIFTTPKSV 990 1000 1010 1020 1030 1040 1000 1010 1020 1030 1040 1050 pF1KA0 PAALKAPKIEKVNDHICEITWECLQPMKGDPVIYSLQVMLGKDSEFKQIYKGPDSSFRYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PAALKAPKIEKVNDHICEITWECLQPMKGDPVIYSLQVMLGKDSEFKQIYKGPDSSFRYS 1050 1060 1070 1080 1090 1100 1060 1070 1080 1090 1100 1110 pF1KA0 SLQLNCEYRFRVCAIRQCQDSLGHQDLVGPYSTTVLFISQRTEPPASTNRDTVESTRTRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLQLNCEYRFRVCAIRQCQDSLGHQDLVGPYSTTVLFISQRTEPPASTNRDTVESTRTRR 1110 1120 1130 1140 1150 1160 1120 1130 1140 pF1KA0 ALSDEQCAAVILVLFAFFSILIAFIIQYFVIK :::::::::::::::::::::::::::::::: NP_001 ALSDEQCAAVILVLFAFFSILIAFIIQYFVIK 1170 1180 1190 >>XP_016875929 (OMIM: 615794) PREDICTED: fibronectin typ (1198 aa) initn: 7839 init1: 7839 opt: 7839 Z-score: 4653.1 bits: 872.9 E(85289): 0 Smith-Waterman score: 7839; 99.8% identity (100.0% similar) in 1142 aa overlap (1-1142:57-1198) 10 20 30 pF1KA0 MSGPAQVPMMSPNGSVPPIYVPPGYAPQVI ..:::::::::::::::::::::::::::: XP_016 SADGTQQVILVQVNPGEAFTIRREDGQFQCITGPAQVPMMSPNGSVPPIYVPPGYAPQVI 30 40 50 60 70 80 40 50 60 70 80 90 pF1KA0 EDNGVRRVVVVPQAPEFHPGSHTVLHRSPHPPLPGFIPVPTMMPPPPRHMYSPVTGAGDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDNGVRRVVVVPQAPEFHPGSHTVLHRSPHPPLPGFIPVPTMMPPPPRHMYSPVTGAGDM 90 100 110 120 130 140 100 110 120 130 140 150 pF1KA0 TTQYMPQYQSSQVYGDVDAHSTHGRSNFRDERSSKTYERLQKKLKDRQGTQKDKMSSPPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TTQYMPQYQSSQVYGDVDAHSTHGRSNFRDERSSKTYERLQKKLKDRQGTQKDKMSSPPS 150 160 170 180 190 200 160 170 180 190 200 210 pF1KA0 SPQKCPSPINEHNGLIKGQIAGGINTGSAKIKSGKGKGGTQVDTEIEEKDEETKAFEALL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPQKCPSPINEHNGLIKGQIAGGINTGSAKIKSGKGKGGTQVDTEIEEKDEETKAFEALL 210 220 230 240 250 260 220 230 240 250 260 270 pF1KA0 SNIVKPVASDIQARTVVLTWSPPSSLINGETDESSVPELYGYEVLISSTGKDGKYKSVYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SNIVKPVASDIQARTVVLTWSPPSSLINGETDESSVPELYGYEVLISSTGKDGKYKSVYV 270 280 290 300 310 320 280 290 300 310 320 330 pF1KA0 GEETNITLNDLKPAMDYHAKVQAEYNSIKGTPSEAEIFTTLSCEPDIPNPPRIANRTKNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GEETNITLNDLKPAMDYHAKVQAEYNSIKGTPSEAEIFTTLSCEPDIPNPPRIANRTKNS 330 340 350 360 370 380 340 350 360 370 380 390 pF1KA0 LTLQWKAPSDNGSKIQNFVLEWDEGKGNGEFCQCYMGSQKQFKITKLSPAMGCKFRLSAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTLQWKAPSDNGSKIQNFVLEWDEGKGNGEFCQCYMGSQKQFKITKLSPAMGCKFRLSAR 390 400 410 420 430 440 400 410 420 430 440 450 pF1KA0 NDYGTSGFSEEVLYYTSGCAPSMPASPVLTKAGITWLSLQWSKPSGTPSDEGISYILEME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NDYGTSGFSEEVLYYTSGCAPSMPASPVLTKAGITWLSLQWSKPSGTPSDEGISYILEME 450 460 470 480 490 500 460 470 480 490 500 510 pF1KA0 EETSGYGFKPKYDGEDLAYTVKNLRRSTKYKFKVIAYNSEGKSNPSEVVEFTTCPDKPGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EETSGYGFKPKYDGEDLAYTVKNLRRSTKYKFKVIAYNSEGKSNPSEVVEFTTCPDKPGI 510 520 530 540 550 560 520 530 540 550 560 570 pF1KA0 PVKPSVKGKIHSHSFKITWDPPKDNGGATINKYVVEMAEGSNGNKWEMIYSGATREHLCD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PVKPSVKGKIHSHSFKITWDPPKDNGGATINKYVVEMAEGSNGNKWEMIYSGATREHLCD 570 580 590 600 610 620 580 590 600 610 620 630 pF1KA0 RLNPGCFYRLRVYCISDGGQSAVSESLLVQTPAVPPGPCLPPRLQGRPKAKEIQLRWGPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLNPGCFYRLRVYCISDGGQSAVSESLLVQTPAVPPGPCLPPRLQGRPKAKEIQLRWGPP 630 640 650 660 670 680 640 650 660 670 680 690 pF1KA0 LVDGGSPISCYSVEMSPIEKDEPREVYQGSEVECTVSSLLPGKTYSFRLRAANKMGFGPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LVDGGSPISCYSVEMSPIEKDEPREVYQGSEVECTVSSLLPGKTYSFRLRAANKMGFGPF 690 700 710 720 730 740 700 710 720 730 740 750 pF1KA0 SEKCDITTAPGPPDQCKPPQVTCRSATCAQVNWEVPLSNGTDVTEYRLEWGGVEGSMQIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SEKCDITTAPGPPDQCKPPQVTCRSATCAQVNWEVPLSNGTDVTEYRLEWGGVEGSMQIC 750 760 770 780 790 800 760 770 780 790 800 810 pF1KA0 YCGPGLSYEIKGLSPATTYYCRVQALSVVGAGPFSEVVACVTPPSVPGIVTCLQEISDDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YCGPGLSYEIKGLSPATTYYCRVQALSVVGAGPFSEVVACVTPPSVPGIVTCLQEISDDE 810 820 830 840 850 860 820 830 840 850 860 870 pF1KA0 IENPHYSPSTCLAISWEKPCDHGSEILAYSIDFGDKQSLTVGKVTSYIINNLQPDTTYRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IENPHYSPSTCLAISWEKPCDHGSEILAYSIDFGDKQSLTVGKVTSYIINNLQPDTTYRI 870 880 890 900 910 920 880 890 900 910 920 930 pF1KA0 RIQALNSLGAGPFSHMIKLKTKPLPPDPPRLECVAFSHQNLKLKWGEGTPKTLSTDSIQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RIQALNSLGAGPFSHMIKLKTKPLPPDPPRLECVAFSHQNLKLKWGEGTPKTLSTDSIQY 930 940 950 960 970 980 940 950 960 970 980 990 pF1KA0 HLQMEDKNGRFVSLYRGPCHTYKVQRLNESTSYKFCIQACNEAGEGPLSQEYIFTTPKSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HLQMEDKNGRFVSLYRGPCHTYKVQRLNESTSYKFCIQACNEAGEGPLSQEYIFTTPKSV 990 1000 1010 1020 1030 1040 1000 1010 1020 1030 1040 1050 pF1KA0 PAALKAPKIEKVNDHICEITWECLQPMKGDPVIYSLQVMLGKDSEFKQIYKGPDSSFRYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PAALKAPKIEKVNDHICEITWECLQPMKGDPVIYSLQVMLGKDSEFKQIYKGPDSSFRYS 1050 1060 1070 1080 1090 1100 1060 1070 1080 1090 1100 1110 pF1KA0 SLQLNCEYRFRVCAIRQCQDSLGHQDLVGPYSTTVLFISQRTEPPASTNRDTVESTRTRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLQLNCEYRFRVCAIRQCQDSLGHQDLVGPYSTTVLFISQRTEPPASTNRDTVESTRTRR 1110 1120 1130 1140 1150 1160 1120 1130 1140 pF1KA0 ALSDEQCAAVILVLFAFFSILIAFIIQYFVIK :::::::::::::::::::::::::::::::: XP_016 ALSDEQCAAVILVLFAFFSILIAFIIQYFVIK 1170 1180 1190 >>XP_011533299 (OMIM: 615794) PREDICTED: fibronectin typ (1134 aa) initn: 7790 init1: 7790 opt: 7790 Z-score: 4624.4 bits: 867.6 E(85289): 0 Smith-Waterman score: 7790; 100.0% identity (100.0% similar) in 1134 aa overlap (9-1142:1-1134) 10 20 30 40 50 60 pF1KA0 MSGPAQVPMMSPNGSVPPIYVPPGYAPQVIEDNGVRRVVVVPQAPEFHPGSHTVLHRSPH :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MMSPNGSVPPIYVPPGYAPQVIEDNGVRRVVVVPQAPEFHPGSHTVLHRSPH 10 20 30 40 50 70 80 90 100 110 120 pF1KA0 PPLPGFIPVPTMMPPPPRHMYSPVTGAGDMTTQYMPQYQSSQVYGDVDAHSTHGRSNFRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPLPGFIPVPTMMPPPPRHMYSPVTGAGDMTTQYMPQYQSSQVYGDVDAHSTHGRSNFRD 60 70 80 90 100 110 130 140 150 160 170 180 pF1KA0 ERSSKTYERLQKKLKDRQGTQKDKMSSPPSSPQKCPSPINEHNGLIKGQIAGGINTGSAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ERSSKTYERLQKKLKDRQGTQKDKMSSPPSSPQKCPSPINEHNGLIKGQIAGGINTGSAK 120 130 140 150 160 170 190 200 210 220 230 240 pF1KA0 IKSGKGKGGTQVDTEIEEKDEETKAFEALLSNIVKPVASDIQARTVVLTWSPPSSLINGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IKSGKGKGGTQVDTEIEEKDEETKAFEALLSNIVKPVASDIQARTVVLTWSPPSSLINGE 180 190 200 210 220 230 250 260 270 280 290 300 pF1KA0 TDESSVPELYGYEVLISSTGKDGKYKSVYVGEETNITLNDLKPAMDYHAKVQAEYNSIKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TDESSVPELYGYEVLISSTGKDGKYKSVYVGEETNITLNDLKPAMDYHAKVQAEYNSIKG 240 250 260 270 280 290 310 320 330 340 350 360 pF1KA0 TPSEAEIFTTLSCEPDIPNPPRIANRTKNSLTLQWKAPSDNGSKIQNFVLEWDEGKGNGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TPSEAEIFTTLSCEPDIPNPPRIANRTKNSLTLQWKAPSDNGSKIQNFVLEWDEGKGNGE 300 310 320 330 340 350 370 380 390 400 410 420 pF1KA0 FCQCYMGSQKQFKITKLSPAMGCKFRLSARNDYGTSGFSEEVLYYTSGCAPSMPASPVLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FCQCYMGSQKQFKITKLSPAMGCKFRLSARNDYGTSGFSEEVLYYTSGCAPSMPASPVLT 360 370 380 390 400 410 430 440 450 460 470 480 pF1KA0 KAGITWLSLQWSKPSGTPSDEGISYILEMEEETSGYGFKPKYDGEDLAYTVKNLRRSTKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KAGITWLSLQWSKPSGTPSDEGISYILEMEEETSGYGFKPKYDGEDLAYTVKNLRRSTKY 420 430 440 450 460 470 490 500 510 520 530 540 pF1KA0 KFKVIAYNSEGKSNPSEVVEFTTCPDKPGIPVKPSVKGKIHSHSFKITWDPPKDNGGATI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KFKVIAYNSEGKSNPSEVVEFTTCPDKPGIPVKPSVKGKIHSHSFKITWDPPKDNGGATI 480 490 500 510 520 530 550 560 570 580 590 600 pF1KA0 NKYVVEMAEGSNGNKWEMIYSGATREHLCDRLNPGCFYRLRVYCISDGGQSAVSESLLVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NKYVVEMAEGSNGNKWEMIYSGATREHLCDRLNPGCFYRLRVYCISDGGQSAVSESLLVQ 540 550 560 570 580 590 610 620 630 640 650 660 pF1KA0 TPAVPPGPCLPPRLQGRPKAKEIQLRWGPPLVDGGSPISCYSVEMSPIEKDEPREVYQGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TPAVPPGPCLPPRLQGRPKAKEIQLRWGPPLVDGGSPISCYSVEMSPIEKDEPREVYQGS 600 610 620 630 640 650 670 680 690 700 710 720 pF1KA0 EVECTVSSLLPGKTYSFRLRAANKMGFGPFSEKCDITTAPGPPDQCKPPQVTCRSATCAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EVECTVSSLLPGKTYSFRLRAANKMGFGPFSEKCDITTAPGPPDQCKPPQVTCRSATCAQ 660 670 680 690 700 710 730 740 750 760 770 780 pF1KA0 VNWEVPLSNGTDVTEYRLEWGGVEGSMQICYCGPGLSYEIKGLSPATTYYCRVQALSVVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VNWEVPLSNGTDVTEYRLEWGGVEGSMQICYCGPGLSYEIKGLSPATTYYCRVQALSVVG 720 730 740 750 760 770 790 800 810 820 830 840 pF1KA0 AGPFSEVVACVTPPSVPGIVTCLQEISDDEIENPHYSPSTCLAISWEKPCDHGSEILAYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AGPFSEVVACVTPPSVPGIVTCLQEISDDEIENPHYSPSTCLAISWEKPCDHGSEILAYS 780 790 800 810 820 830 850 860 870 880 890 900 pF1KA0 IDFGDKQSLTVGKVTSYIINNLQPDTTYRIRIQALNSLGAGPFSHMIKLKTKPLPPDPPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IDFGDKQSLTVGKVTSYIINNLQPDTTYRIRIQALNSLGAGPFSHMIKLKTKPLPPDPPR 840 850 860 870 880 890 910 920 930 940 950 960 pF1KA0 LECVAFSHQNLKLKWGEGTPKTLSTDSIQYHLQMEDKNGRFVSLYRGPCHTYKVQRLNES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LECVAFSHQNLKLKWGEGTPKTLSTDSIQYHLQMEDKNGRFVSLYRGPCHTYKVQRLNES 900 910 920 930 940 950 970 980 990 1000 1010 1020 pF1KA0 TSYKFCIQACNEAGEGPLSQEYIFTTPKSVPAALKAPKIEKVNDHICEITWECLQPMKGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSYKFCIQACNEAGEGPLSQEYIFTTPKSVPAALKAPKIEKVNDHICEITWECLQPMKGD 960 970 980 990 1000 1010 1030 1040 1050 1060 1070 1080 pF1KA0 PVIYSLQVMLGKDSEFKQIYKGPDSSFRYSSLQLNCEYRFRVCAIRQCQDSLGHQDLVGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVIYSLQVMLGKDSEFKQIYKGPDSSFRYSSLQLNCEYRFRVCAIRQCQDSLGHQDLVGP 1020 1030 1040 1050 1060 1070 1090 1100 1110 1120 1130 1140 pF1KA0 YSTTVLFISQRTEPPASTNRDTVESTRTRRALSDEQCAAVILVLFAFFSILIAFIIQYFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YSTTVLFISQRTEPPASTNRDTVESTRTRRALSDEQCAAVILVLFAFFSILIAFIIQYFV 1080 1090 1100 1110 1120 1130 pF1KA0 IK :: XP_011 IK >>XP_016875931 (OMIM: 615794) PREDICTED: fibronectin typ (1134 aa) initn: 7790 init1: 7790 opt: 7790 Z-score: 4624.4 bits: 867.6 E(85289): 0 Smith-Waterman score: 7790; 100.0% identity (100.0% similar) in 1134 aa overlap (9-1142:1-1134) 10 20 30 40 50 60 pF1KA0 MSGPAQVPMMSPNGSVPPIYVPPGYAPQVIEDNGVRRVVVVPQAPEFHPGSHTVLHRSPH :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MMSPNGSVPPIYVPPGYAPQVIEDNGVRRVVVVPQAPEFHPGSHTVLHRSPH 10 20 30 40 50 70 80 90 100 110 120 pF1KA0 PPLPGFIPVPTMMPPPPRHMYSPVTGAGDMTTQYMPQYQSSQVYGDVDAHSTHGRSNFRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPLPGFIPVPTMMPPPPRHMYSPVTGAGDMTTQYMPQYQSSQVYGDVDAHSTHGRSNFRD 60 70 80 90 100 110 130 140 150 160 170 180 pF1KA0 ERSSKTYERLQKKLKDRQGTQKDKMSSPPSSPQKCPSPINEHNGLIKGQIAGGINTGSAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ERSSKTYERLQKKLKDRQGTQKDKMSSPPSSPQKCPSPINEHNGLIKGQIAGGINTGSAK 120 130 140 150 160 170 190 200 210 220 230 240 pF1KA0 IKSGKGKGGTQVDTEIEEKDEETKAFEALLSNIVKPVASDIQARTVVLTWSPPSSLINGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IKSGKGKGGTQVDTEIEEKDEETKAFEALLSNIVKPVASDIQARTVVLTWSPPSSLINGE 180 190 200 210 220 230 250 260 270 280 290 300 pF1KA0 TDESSVPELYGYEVLISSTGKDGKYKSVYVGEETNITLNDLKPAMDYHAKVQAEYNSIKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TDESSVPELYGYEVLISSTGKDGKYKSVYVGEETNITLNDLKPAMDYHAKVQAEYNSIKG 240 250 260 270 280 290 310 320 330 340 350 360 pF1KA0 TPSEAEIFTTLSCEPDIPNPPRIANRTKNSLTLQWKAPSDNGSKIQNFVLEWDEGKGNGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPSEAEIFTTLSCEPDIPNPPRIANRTKNSLTLQWKAPSDNGSKIQNFVLEWDEGKGNGE 300 310 320 330 340 350 370 380 390 400 410 420 pF1KA0 FCQCYMGSQKQFKITKLSPAMGCKFRLSARNDYGTSGFSEEVLYYTSGCAPSMPASPVLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FCQCYMGSQKQFKITKLSPAMGCKFRLSARNDYGTSGFSEEVLYYTSGCAPSMPASPVLT 360 370 380 390 400 410 430 440 450 460 470 480 pF1KA0 KAGITWLSLQWSKPSGTPSDEGISYILEMEEETSGYGFKPKYDGEDLAYTVKNLRRSTKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KAGITWLSLQWSKPSGTPSDEGISYILEMEEETSGYGFKPKYDGEDLAYTVKNLRRSTKY 420 430 440 450 460 470 490 500 510 520 530 540 pF1KA0 KFKVIAYNSEGKSNPSEVVEFTTCPDKPGIPVKPSVKGKIHSHSFKITWDPPKDNGGATI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KFKVIAYNSEGKSNPSEVVEFTTCPDKPGIPVKPSVKGKIHSHSFKITWDPPKDNGGATI 480 490 500 510 520 530 550 560 570 580 590 600 pF1KA0 NKYVVEMAEGSNGNKWEMIYSGATREHLCDRLNPGCFYRLRVYCISDGGQSAVSESLLVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NKYVVEMAEGSNGNKWEMIYSGATREHLCDRLNPGCFYRLRVYCISDGGQSAVSESLLVQ 540 550 560 570 580 590 610 620 630 640 650 660 pF1KA0 TPAVPPGPCLPPRLQGRPKAKEIQLRWGPPLVDGGSPISCYSVEMSPIEKDEPREVYQGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPAVPPGPCLPPRLQGRPKAKEIQLRWGPPLVDGGSPISCYSVEMSPIEKDEPREVYQGS 600 610 620 630 640 650 670 680 690 700 710 720 pF1KA0 EVECTVSSLLPGKTYSFRLRAANKMGFGPFSEKCDITTAPGPPDQCKPPQVTCRSATCAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EVECTVSSLLPGKTYSFRLRAANKMGFGPFSEKCDITTAPGPPDQCKPPQVTCRSATCAQ 660 670 680 690 700 710 730 740 750 760 770 780 pF1KA0 VNWEVPLSNGTDVTEYRLEWGGVEGSMQICYCGPGLSYEIKGLSPATTYYCRVQALSVVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNWEVPLSNGTDVTEYRLEWGGVEGSMQICYCGPGLSYEIKGLSPATTYYCRVQALSVVG 720 730 740 750 760 770 790 800 810 820 830 840 pF1KA0 AGPFSEVVACVTPPSVPGIVTCLQEISDDEIENPHYSPSTCLAISWEKPCDHGSEILAYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGPFSEVVACVTPPSVPGIVTCLQEISDDEIENPHYSPSTCLAISWEKPCDHGSEILAYS 780 790 800 810 820 830 850 860 870 880 890 900 pF1KA0 IDFGDKQSLTVGKVTSYIINNLQPDTTYRIRIQALNSLGAGPFSHMIKLKTKPLPPDPPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IDFGDKQSLTVGKVTSYIINNLQPDTTYRIRIQALNSLGAGPFSHMIKLKTKPLPPDPPR 840 850 860 870 880 890 910 920 930 940 950 960 pF1KA0 LECVAFSHQNLKLKWGEGTPKTLSTDSIQYHLQMEDKNGRFVSLYRGPCHTYKVQRLNES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LECVAFSHQNLKLKWGEGTPKTLSTDSIQYHLQMEDKNGRFVSLYRGPCHTYKVQRLNES 900 910 920 930 940 950 970 980 990 1000 1010 1020 pF1KA0 TSYKFCIQACNEAGEGPLSQEYIFTTPKSVPAALKAPKIEKVNDHICEITWECLQPMKGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSYKFCIQACNEAGEGPLSQEYIFTTPKSVPAALKAPKIEKVNDHICEITWECLQPMKGD 960 970 980 990 1000 1010 1030 1040 1050 1060 1070 1080 pF1KA0 PVIYSLQVMLGKDSEFKQIYKGPDSSFRYSSLQLNCEYRFRVCAIRQCQDSLGHQDLVGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PVIYSLQVMLGKDSEFKQIYKGPDSSFRYSSLQLNCEYRFRVCAIRQCQDSLGHQDLVGP 1020 1030 1040 1050 1060 1070 1090 1100 1110 1120 1130 1140 pF1KA0 YSTTVLFISQRTEPPASTNRDTVESTRTRRALSDEQCAAVILVLFAFFSILIAFIIQYFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YSTTVLFISQRTEPPASTNRDTVESTRTRRALSDEQCAAVILVLFAFFSILIAFIIQYFV 1080 1090 1100 1110 1120 1130 pF1KA0 IK :: XP_016 IK >>XP_016875930 (OMIM: 615794) PREDICTED: fibronectin typ (1134 aa) initn: 7790 init1: 7790 opt: 7790 Z-score: 4624.4 bits: 867.6 E(85289): 0 Smith-Waterman score: 7790; 100.0% identity (100.0% similar) in 1134 aa overlap (9-1142:1-1134) 10 20 30 40 50 60 pF1KA0 MSGPAQVPMMSPNGSVPPIYVPPGYAPQVIEDNGVRRVVVVPQAPEFHPGSHTVLHRSPH :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MMSPNGSVPPIYVPPGYAPQVIEDNGVRRVVVVPQAPEFHPGSHTVLHRSPH 10 20 30 40 50 70 80 90 100 110 120 pF1KA0 PPLPGFIPVPTMMPPPPRHMYSPVTGAGDMTTQYMPQYQSSQVYGDVDAHSTHGRSNFRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPLPGFIPVPTMMPPPPRHMYSPVTGAGDMTTQYMPQYQSSQVYGDVDAHSTHGRSNFRD 60 70 80 90 100 110 130 140 150 160 170 180 pF1KA0 ERSSKTYERLQKKLKDRQGTQKDKMSSPPSSPQKCPSPINEHNGLIKGQIAGGINTGSAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ERSSKTYERLQKKLKDRQGTQKDKMSSPPSSPQKCPSPINEHNGLIKGQIAGGINTGSAK 120 130 140 150 160 170 190 200 210 220 230 240 pF1KA0 IKSGKGKGGTQVDTEIEEKDEETKAFEALLSNIVKPVASDIQARTVVLTWSPPSSLINGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IKSGKGKGGTQVDTEIEEKDEETKAFEALLSNIVKPVASDIQARTVVLTWSPPSSLINGE 180 190 200 210 220 230 250 260 270 280 290 300 pF1KA0 TDESSVPELYGYEVLISSTGKDGKYKSVYVGEETNITLNDLKPAMDYHAKVQAEYNSIKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TDESSVPELYGYEVLISSTGKDGKYKSVYVGEETNITLNDLKPAMDYHAKVQAEYNSIKG 240 250 260 270 280 290 310 320 330 340 350 360 pF1KA0 TPSEAEIFTTLSCEPDIPNPPRIANRTKNSLTLQWKAPSDNGSKIQNFVLEWDEGKGNGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPSEAEIFTTLSCEPDIPNPPRIANRTKNSLTLQWKAPSDNGSKIQNFVLEWDEGKGNGE 300 310 320 330 340 350 370 380 390 400 410 420 pF1KA0 FCQCYMGSQKQFKITKLSPAMGCKFRLSARNDYGTSGFSEEVLYYTSGCAPSMPASPVLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FCQCYMGSQKQFKITKLSPAMGCKFRLSARNDYGTSGFSEEVLYYTSGCAPSMPASPVLT 360 370 380 390 400 410 430 440 450 460 470 480 pF1KA0 KAGITWLSLQWSKPSGTPSDEGISYILEMEEETSGYGFKPKYDGEDLAYTVKNLRRSTKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KAGITWLSLQWSKPSGTPSDEGISYILEMEEETSGYGFKPKYDGEDLAYTVKNLRRSTKY 420 430 440 450 460 470 490 500 510 520 530 540 pF1KA0 KFKVIAYNSEGKSNPSEVVEFTTCPDKPGIPVKPSVKGKIHSHSFKITWDPPKDNGGATI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KFKVIAYNSEGKSNPSEVVEFTTCPDKPGIPVKPSVKGKIHSHSFKITWDPPKDNGGATI 480 490 500 510 520 530 550 560 570 580 590 600 pF1KA0 NKYVVEMAEGSNGNKWEMIYSGATREHLCDRLNPGCFYRLRVYCISDGGQSAVSESLLVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NKYVVEMAEGSNGNKWEMIYSGATREHLCDRLNPGCFYRLRVYCISDGGQSAVSESLLVQ 540 550 560 570 580 590 610 620 630 640 650 660 pF1KA0 TPAVPPGPCLPPRLQGRPKAKEIQLRWGPPLVDGGSPISCYSVEMSPIEKDEPREVYQGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPAVPPGPCLPPRLQGRPKAKEIQLRWGPPLVDGGSPISCYSVEMSPIEKDEPREVYQGS 600 610 620 630 640 650 670 680 690 700 710 720 pF1KA0 EVECTVSSLLPGKTYSFRLRAANKMGFGPFSEKCDITTAPGPPDQCKPPQVTCRSATCAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EVECTVSSLLPGKTYSFRLRAANKMGFGPFSEKCDITTAPGPPDQCKPPQVTCRSATCAQ 660 670 680 690 700 710 730 740 750 760 770 780 pF1KA0 VNWEVPLSNGTDVTEYRLEWGGVEGSMQICYCGPGLSYEIKGLSPATTYYCRVQALSVVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNWEVPLSNGTDVTEYRLEWGGVEGSMQICYCGPGLSYEIKGLSPATTYYCRVQALSVVG 720 730 740 750 760 770 790 800 810 820 830 840 pF1KA0 AGPFSEVVACVTPPSVPGIVTCLQEISDDEIENPHYSPSTCLAISWEKPCDHGSEILAYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGPFSEVVACVTPPSVPGIVTCLQEISDDEIENPHYSPSTCLAISWEKPCDHGSEILAYS 780 790 800 810 820 830 850 860 870 880 890 900 pF1KA0 IDFGDKQSLTVGKVTSYIINNLQPDTTYRIRIQALNSLGAGPFSHMIKLKTKPLPPDPPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IDFGDKQSLTVGKVTSYIINNLQPDTTYRIRIQALNSLGAGPFSHMIKLKTKPLPPDPPR 840 850 860 870 880 890 910 920 930 940 950 960 pF1KA0 LECVAFSHQNLKLKWGEGTPKTLSTDSIQYHLQMEDKNGRFVSLYRGPCHTYKVQRLNES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LECVAFSHQNLKLKWGEGTPKTLSTDSIQYHLQMEDKNGRFVSLYRGPCHTYKVQRLNES 900 910 920 930 940 950 970 980 990 1000 1010 1020 pF1KA0 TSYKFCIQACNEAGEGPLSQEYIFTTPKSVPAALKAPKIEKVNDHICEITWECLQPMKGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSYKFCIQACNEAGEGPLSQEYIFTTPKSVPAALKAPKIEKVNDHICEITWECLQPMKGD 960 970 980 990 1000 1010 1030 1040 1050 1060 1070 1080 pF1KA0 PVIYSLQVMLGKDSEFKQIYKGPDSSFRYSSLQLNCEYRFRVCAIRQCQDSLGHQDLVGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PVIYSLQVMLGKDSEFKQIYKGPDSSFRYSSLQLNCEYRFRVCAIRQCQDSLGHQDLVGP 1020 1030 1040 1050 1060 1070 1090 1100 1110 1120 1130 1140 pF1KA0 YSTTVLFISQRTEPPASTNRDTVESTRTRRALSDEQCAAVILVLFAFFSILIAFIIQYFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YSTTVLFISQRTEPPASTNRDTVESTRTRRALSDEQCAAVILVLFAFFSILIAFIIQYFV 1080 1090 1100 1110 1120 1130 pF1KA0 IK :: XP_016 IK >>XP_016875932 (OMIM: 615794) PREDICTED: fibronectin typ (1041 aa) initn: 6478 init1: 6478 opt: 6478 Z-score: 3848.8 bits: 723.9 E(85289): 1.2e-207 Smith-Waterman score: 6478; 99.8% identity (100.0% similar) in 940 aa overlap (1-940:57-996) 10 20 30 pF1KA0 MSGPAQVPMMSPNGSVPPIYVPPGYAPQVI ..:::::::::::::::::::::::::::: XP_016 SADGTQQVILVQVNPGEAFTIRREDGQFQCITGPAQVPMMSPNGSVPPIYVPPGYAPQVI 30 40 50 60 70 80 40 50 60 70 80 90 pF1KA0 EDNGVRRVVVVPQAPEFHPGSHTVLHRSPHPPLPGFIPVPTMMPPPPRHMYSPVTGAGDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDNGVRRVVVVPQAPEFHPGSHTVLHRSPHPPLPGFIPVPTMMPPPPRHMYSPVTGAGDM 90 100 110 120 130 140 100 110 120 130 140 150 pF1KA0 TTQYMPQYQSSQVYGDVDAHSTHGRSNFRDERSSKTYERLQKKLKDRQGTQKDKMSSPPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TTQYMPQYQSSQVYGDVDAHSTHGRSNFRDERSSKTYERLQKKLKDRQGTQKDKMSSPPS 150 160 170 180 190 200 160 170 180 190 200 210 pF1KA0 SPQKCPSPINEHNGLIKGQIAGGINTGSAKIKSGKGKGGTQVDTEIEEKDEETKAFEALL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPQKCPSPINEHNGLIKGQIAGGINTGSAKIKSGKGKGGTQVDTEIEEKDEETKAFEALL 210 220 230 240 250 260 220 230 240 250 260 270 pF1KA0 SNIVKPVASDIQARTVVLTWSPPSSLINGETDESSVPELYGYEVLISSTGKDGKYKSVYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SNIVKPVASDIQARTVVLTWSPPSSLINGETDESSVPELYGYEVLISSTGKDGKYKSVYV 270 280 290 300 310 320 280 290 300 310 320 330 pF1KA0 GEETNITLNDLKPAMDYHAKVQAEYNSIKGTPSEAEIFTTLSCEPDIPNPPRIANRTKNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GEETNITLNDLKPAMDYHAKVQAEYNSIKGTPSEAEIFTTLSCEPDIPNPPRIANRTKNS 330 340 350 360 370 380 340 350 360 370 380 390 pF1KA0 LTLQWKAPSDNGSKIQNFVLEWDEGKGNGEFCQCYMGSQKQFKITKLSPAMGCKFRLSAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTLQWKAPSDNGSKIQNFVLEWDEGKGNGEFCQCYMGSQKQFKITKLSPAMGCKFRLSAR 390 400 410 420 430 440 400 410 420 430 440 450 pF1KA0 NDYGTSGFSEEVLYYTSGCAPSMPASPVLTKAGITWLSLQWSKPSGTPSDEGISYILEME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NDYGTSGFSEEVLYYTSGCAPSMPASPVLTKAGITWLSLQWSKPSGTPSDEGISYILEME 450 460 470 480 490 500 460 470 480 490 500 510 pF1KA0 EETSGYGFKPKYDGEDLAYTVKNLRRSTKYKFKVIAYNSEGKSNPSEVVEFTTCPDKPGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EETSGYGFKPKYDGEDLAYTVKNLRRSTKYKFKVIAYNSEGKSNPSEVVEFTTCPDKPGI 510 520 530 540 550 560 520 530 540 550 560 570 pF1KA0 PVKPSVKGKIHSHSFKITWDPPKDNGGATINKYVVEMAEGSNGNKWEMIYSGATREHLCD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PVKPSVKGKIHSHSFKITWDPPKDNGGATINKYVVEMAEGSNGNKWEMIYSGATREHLCD 570 580 590 600 610 620 580 590 600 610 620 630 pF1KA0 RLNPGCFYRLRVYCISDGGQSAVSESLLVQTPAVPPGPCLPPRLQGRPKAKEIQLRWGPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLNPGCFYRLRVYCISDGGQSAVSESLLVQTPAVPPGPCLPPRLQGRPKAKEIQLRWGPP 630 640 650 660 670 680 640 650 660 670 680 690 pF1KA0 LVDGGSPISCYSVEMSPIEKDEPREVYQGSEVECTVSSLLPGKTYSFRLRAANKMGFGPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LVDGGSPISCYSVEMSPIEKDEPREVYQGSEVECTVSSLLPGKTYSFRLRAANKMGFGPF 690 700 710 720 730 740 700 710 720 730 740 750 pF1KA0 SEKCDITTAPGPPDQCKPPQVTCRSATCAQVNWEVPLSNGTDVTEYRLEWGGVEGSMQIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SEKCDITTAPGPPDQCKPPQVTCRSATCAQVNWEVPLSNGTDVTEYRLEWGGVEGSMQIC 750 760 770 780 790 800 760 770 780 790 800 810 pF1KA0 YCGPGLSYEIKGLSPATTYYCRVQALSVVGAGPFSEVVACVTPPSVPGIVTCLQEISDDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YCGPGLSYEIKGLSPATTYYCRVQALSVVGAGPFSEVVACVTPPSVPGIVTCLQEISDDE 810 820 830 840 850 860 820 830 840 850 860 870 pF1KA0 IENPHYSPSTCLAISWEKPCDHGSEILAYSIDFGDKQSLTVGKVTSYIINNLQPDTTYRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IENPHYSPSTCLAISWEKPCDHGSEILAYSIDFGDKQSLTVGKVTSYIINNLQPDTTYRI 870 880 890 900 910 920 880 890 900 910 920 930 pF1KA0 RIQALNSLGAGPFSHMIKLKTKPLPPDPPRLECVAFSHQNLKLKWGEGTPKTLSTDSIQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RIQALNSLGAGPFSHMIKLKTKPLPPDPPRLECVAFSHQNLKLKWGEGTPKTLSTDSIQY 930 940 950 960 970 980 940 950 960 970 980 990 pF1KA0 HLQMEDKNGRFVSLYRGPCHTYKVQRLNESTSYKFCIQACNEAGEGPLSQEYIFTTPKSV :::::::::: XP_016 HLQMEDKNGRNIQSKIMGCIQLIDNILGEICMIFNFIEQFKWVMYWKFYIIILLL 990 1000 1010 1020 1030 1040 >>NP_073600 (OMIM: 611909) fibronectin type III domain-c (1204 aa) initn: 3182 init1: 1854 opt: 3963 Z-score: 2360.2 bits: 448.7 E(85289): 1e-124 Smith-Waterman score: 3963; 51.3% identity (75.8% similar) in 1155 aa overlap (1-1142:61-1204) 10 20 30 pF1KA0 MSGPAQVPMMSPNGSVPPIYVPPGYAPQVI ..:::.:::::::::.:::.::::: ::: NP_073 NGDAAQQVILVQVNPGETFTIRAEDGTLQCIQGPAEVPMMSPNGSIPPIHVPPGYISQVI 40 50 60 70 80 90 40 50 60 70 80 pF1KA0 EDN-GVRRVVVVPQAPEFHPGSH-TVLHRSPHPPLPGFIPVPTMMPPPPRHMYSPVTGAG ::. :::::::.::.:: .: :. ... . : : : . : .. .: :::: : NP_073 EDSTGVRRVVVTPQSPECYPPSYPSAMSPTHHLP-PYLTHHPHFIHNSHTAYYPPVTGPG 100 110 120 130 140 90 100 110 120 130 140 pF1KA0 DMTTQYMPQYQSSQ-VYGDVDAHSTHGRSNF--RDERSSKTYERLQKKLKDRQGTQKDKM :: :..::.. . .::. . .: :.. :... :: .::::::: ..... NP_073 DMPPQFFPQHHLPHTIYGEQEIIPFYGMSTYITREDQYSKPP---HKKLKDRQIDRQNRL 150 160 170 180 190 200 150 160 170 180 190 pF1KA0 SSPPSSPQKCPSPINEHNGLIKGQI--AGGINTGSAK-IKSGKGKGGTQV---DTEIEEK .::::: : : . .:: ::. .:: ..::. ::. . .. .. :....: NP_073 NSPPSSIYKS-SCTTVYNGYGKGHSGGSGGGGSGSGPGIKKTERRARSSPKSNDSDLQEY 210 220 230 240 250 260 200 210 220 230 240 250 pF1KA0 DEETKAFEALLSNIVKPVASDIQARTVVLTWSPPSSLINGETDESSVPELYGYEVLISST . :.: . .::.: :: .:.::::.:::.:.:: .: : . : : :.::: .:. NP_073 ELEVKRVQDILSGIEKPQVSNIQARAVVLSWAPPVGLSCGPHSGLSFP--YSYEVALSDK 270 280 290 300 310 320 260 270 280 290 300 310 pF1KA0 GKDGKYKSVYVGEETNITLNDLKPAMDYHAKVQAEYNSIKGTPSEAEIFTTLSCEPDIPN :.::::: .: ::: . .:.::.:: :::..: : :::.::. :: ::: :: :. : NP_073 GRDGKYKIIYSGEELECNLKDLRPATDYHVRVYAMYNSVKGSCSEPVSFTTHSCAPECPF 330 340 350 360 370 380 320 330 340 350 360 370 pF1KA0 PPRIANRTKNSLTLQWKAPSDNGSKIQNFVLEWDEGKGNGEFCQCYMGSQKQFKITKLSP ::..:.:.:.::::::::: :::::: :..::::::: :. : ::..::::. :.::: : NP_073 PPKLAHRSKSSLTLQWKAPIDNGSKITNYLLEWDEGKRNSGFRQCFFGSQKHCKLTKLCP 390 400 410 420 430 440 380 390 400 410 420 430 pF1KA0 AMGCKFRLSARNDYGTSGFSEEVLYYTSGCAPSMPASPVLTKAGITWLSLQWSKPSGTPS ::: :::.:::: ::::.:.::. :: : :.::..: :..:::::..:::::: : NP_073 AMGYTFRLAARNDIGTSGYSQEVVCYTLGNIPQMPSAPRLVRAGITWVTLQWSKPEGCSP 450 460 470 480 490 500 440 450 460 470 480 490 pF1KA0 DEGISYILEMEEETSGYGFKPKYDGEDLAYTVKNLRRSTKYKFKVIAYNSEGKSNPSEVV .: :.: ::..:. . :.::: ::::. :::::.:::.:::.. : :.:::: ::::. NP_073 EEVITYTLEIQEDENDNLFHPKYTGEDLTCTVKNLKRSTQYKFRLTASNTEGKSCPSEVL 510 520 530 540 550 560 500 510 520 530 540 550 pF1KA0 EFTTCPDKPGIPVKPSVKGKIHSHSFKITWDPPKDNGGATINKYVVEMAEG-SNGNKWEM :: ::.:: :..: ::: . ::.:.. :::::::::. : ::..:...: :..:.::. NP_073 VCTTSPDRPGPPTRPLVKGPVTSHGFSVKWDPPKDNGGSEILKYLLEITDGNSEANQWEV 570 580 590 600 610 620 560 570 580 590 600 610 pF1KA0 IYSGATREHLCDRLNPGCFYRLRVYCISDGGQSAVSESLLVQTPAVPPGPCLPPRLQGRP :::.. :. .:.:: .:.::. ::: ::.: :::: :.: .. :: : :::. ::: NP_073 AYSGSATEYTFTHLKPGTLYKLRACCISTGGHSQCSESLPVRTLSIAPGQCRPPRVLGRP 630 640 650 660 670 680 620 630 640 650 660 670 pF1KA0 KAKEIQLRWGPPLVDGGSPISCYSVEMSPIEKDEPREVYQGSEVECTVSSLLPGKTYSFR : ::..:.: : ..: .: :::::. : : :::.: :.::::..:::: .: :: NP_073 KHKEVHLEWDVPASESGCEVSEYSVEMTEPE-DVASEVYHGPELECTVGNLLPGTVYRFR 690 700 710 720 730 740 680 690 700 710 720 730 pF1KA0 LRAANKMGFGPFSEKCDITTAPGPPDQCKPPQVTCRSATCAQVNWEVPLSNGTDVTEYRL .:: : :.::.:. .:::: ::: ::: : ..: :. :.:: : :.:.:..:::: NP_073 VRALNDGGYGPYSDVSEITTAAGPPGQCKAPCISCTPDGCVLVGWESPDSSGADISEYRL 750 760 770 780 790 800 740 750 760 770 780 790 pF1KA0 EWGGVEGSMQICYCGPGLSYEIKGLSPATTYYCRVQALSVVGAGPFSEVVACVTPPSVPG ::: : :... : : .::. : ::. : ::.::.. .::::.::.: : :: :.: NP_073 EWGEDEESLELIYHGTDTRFEIRDLLPAAQYCCRLQAFNQAGAGPYSELVLCQTPASAPD 810 820 830 840 850 860 800 810 820 830 840 850 pF1KA0 IVTCLQEISDDEIENPHYSPSTCLAISWEKPCDHGSEILAYSIDFGDKQSLTVGKVTSYI :. : . .. .. :::.::...::.::..:::::::.::.:: :.:::..: .. NP_073 PVSTLCVLEEEPLDAYPDSPSACLVLNWEEPCNNGSEILAYTIDLGDT-SITVGNTTMHV 870 880 890 900 910 920 860 870 880 890 900 910 pF1KA0 INNLQPDTTYRIRIQALNSLGAGPFSHMIKLKTKPLPPDPPRLECVAFSHQNLKLKWGEG ...: :.:::::::::.: .::::::..:: ::.:::: ::::::.: . :.::::::.. NP_073 MKDLLPETTYRIRIQAINEIGAGPFSQFIKAKTRPLPPLPPRLECAAAGPQSLKLKWGDS 930 940 950 960 970 980 920 930 940 950 960 970 pF1KA0 TPKTLSTDSIQYHLQMEDKNGRFVSLYRGPCHTYKVQRLNESTSYKFCIQACNEAGEGPL . :: ....: : ::.::.: ::.:.:::: ::::::::.: : :.: ::: .::::::. NP_073 NSKTHAAEDIVYTLQLEDRNKRFISIYRGPSHTYKVQRLTEFTCYSFRIQAASEAGEGPF 990 1000 1010 1020 1030 1040 980 990 1000 1010 1020 1030 pF1KA0 SQEYIFTTPKSVPAALKAPKIEKVNDHICEITWECLQPMKGDPVIYSLQVMLGKDSEFKQ :. : :.: :::: ..:::.. ... . ::: :: . :::::: : :::..:..::.:: NP_073 SETYTFSTTKSVPPTIKAPRVTQLEGNSCEILWETVPSMKGDPVNYILQVLVGRESEYKQ 1050 1060 1070 1080 1090 1100 1040 1050 1060 1070 1080 1090 pF1KA0 IYKGPDSSFRYSSLQLNCEYRFRVCAIRQCQDSLGHQDLVGPYSTTVLFISQRTEPPAST .::: ...:. :.:: : .::::::: :.: :. :.: : .: .. :. ::.: . NP_073 VYKGEEATFQISGLQTNTDYRFRVCACRRCLDT--SQELSGAFSPSAAFVLQRSEVMLTG 1110 1120 1130 1140 1150 1100 1110 1120 1130 1140 pF1KA0 NRDTVESTRTRRAL-SDEQCAAVILVLFAFFSILIAFIIQYFVIK . .... . . . .::: ::.:.. :: .:::.:::.:::..: NP_073 DMGSLDDPKMKSMMPTDEQFAAIIVLGFATLSILFAFILQYFLMK 1160 1170 1180 1190 1200 >>NP_001128567 (OMIM: 611909) fibronectin type III domai (1204 aa) initn: 3182 init1: 1854 opt: 3963 Z-score: 2360.2 bits: 448.7 E(85289): 1e-124 Smith-Waterman score: 3963; 51.3% identity (75.8% similar) in 1155 aa overlap (1-1142:61-1204) 10 20 30 pF1KA0 MSGPAQVPMMSPNGSVPPIYVPPGYAPQVI ..:::.:::::::::.:::.::::: ::: NP_001 NGDAAQQVILVQVNPGETFTIRAEDGTLQCIQGPAEVPMMSPNGSIPPIHVPPGYISQVI 40 50 60 70 80 90 40 50 60 70 80 pF1KA0 EDN-GVRRVVVVPQAPEFHPGSH-TVLHRSPHPPLPGFIPVPTMMPPPPRHMYSPVTGAG ::. :::::::.::.:: .: :. ... . : : : . : .. .: :::: : NP_001 EDSTGVRRVVVTPQSPECYPPSYPSAMSPTHHLP-PYLTHHPHFIHNSHTAYYPPVTGPG 100 110 120 130 140 90 100 110 120 130 140 pF1KA0 DMTTQYMPQYQSSQ-VYGDVDAHSTHGRSNF--RDERSSKTYERLQKKLKDRQGTQKDKM :: :..::.. . .::. . .: :.. :... :: .::::::: ..... NP_001 DMPPQFFPQHHLPHTIYGEQEIIPFYGMSTYITREDQYSKPP---HKKLKDRQIDRQNRL 150 160 170 180 190 200 150 160 170 180 190 pF1KA0 SSPPSSPQKCPSPINEHNGLIKGQI--AGGINTGSAK-IKSGKGKGGTQV---DTEIEEK .::::: : : . .:: ::. .:: ..::. ::. . .. .. :....: NP_001 NSPPSSIYKS-SCTTVYNGYGKGHSGGSGGGGSGSGPGIKKTERRARSSPKSNDSDLQEY 210 220 230 240 250 260 200 210 220 230 240 250 pF1KA0 DEETKAFEALLSNIVKPVASDIQARTVVLTWSPPSSLINGETDESSVPELYGYEVLISST . :.: . .::.: :: .:.::::.:::.:.:: .: : . : : :.::: .:. NP_001 ELEVKRVQDILSGIEKPQVSNIQARAVVLSWAPPVGLSCGPHSGLSFP--YSYEVALSDK 270 280 290 300 310 320 260 270 280 290 300 310 pF1KA0 GKDGKYKSVYVGEETNITLNDLKPAMDYHAKVQAEYNSIKGTPSEAEIFTTLSCEPDIPN :.::::: .: ::: . .:.::.:: :::..: : :::.::. :: ::: :: :. : NP_001 GRDGKYKIIYSGEELECNLKDLRPATDYHVRVYAMYNSVKGSCSEPVSFTTHSCAPECPF 330 340 350 360 370 380 320 330 340 350 360 370 pF1KA0 PPRIANRTKNSLTLQWKAPSDNGSKIQNFVLEWDEGKGNGEFCQCYMGSQKQFKITKLSP ::..:.:.:.::::::::: :::::: :..::::::: :. : ::..::::. :.::: : NP_001 PPKLAHRSKSSLTLQWKAPIDNGSKITNYLLEWDEGKRNSGFRQCFFGSQKHCKLTKLCP 390 400 410 420 430 440 380 390 400 410 420 430 pF1KA0 AMGCKFRLSARNDYGTSGFSEEVLYYTSGCAPSMPASPVLTKAGITWLSLQWSKPSGTPS ::: :::.:::: ::::.:.::. :: : :.::..: :..:::::..:::::: : NP_001 AMGYTFRLAARNDIGTSGYSQEVVCYTLGNIPQMPSAPRLVRAGITWVTLQWSKPEGCSP 450 460 470 480 490 500 440 450 460 470 480 490 pF1KA0 DEGISYILEMEEETSGYGFKPKYDGEDLAYTVKNLRRSTKYKFKVIAYNSEGKSNPSEVV .: :.: ::..:. . :.::: ::::. :::::.:::.:::.. : :.:::: ::::. NP_001 EEVITYTLEIQEDENDNLFHPKYTGEDLTCTVKNLKRSTQYKFRLTASNTEGKSCPSEVL 510 520 530 540 550 560 500 510 520 530 540 550 pF1KA0 EFTTCPDKPGIPVKPSVKGKIHSHSFKITWDPPKDNGGATINKYVVEMAEG-SNGNKWEM :: ::.:: :..: ::: . ::.:.. :::::::::. : ::..:...: :..:.::. NP_001 VCTTSPDRPGPPTRPLVKGPVTSHGFSVKWDPPKDNGGSEILKYLLEITDGNSEANQWEV 570 580 590 600 610 620 560 570 580 590 600 610 pF1KA0 IYSGATREHLCDRLNPGCFYRLRVYCISDGGQSAVSESLLVQTPAVPPGPCLPPRLQGRP :::.. :. .:.:: .:.::. ::: ::.: :::: :.: .. :: : :::. ::: NP_001 AYSGSATEYTFTHLKPGTLYKLRACCISTGGHSQCSESLPVRTLSIAPGQCRPPRVLGRP 630 640 650 660 670 680 620 630 640 650 660 670 pF1KA0 KAKEIQLRWGPPLVDGGSPISCYSVEMSPIEKDEPREVYQGSEVECTVSSLLPGKTYSFR : ::..:.: : ..: .: :::::. : : :::.: :.::::..:::: .: :: NP_001 KHKEVHLEWDVPASESGCEVSEYSVEMTEPE-DVASEVYHGPELECTVGNLLPGTVYRFR 690 700 710 720 730 740 680 690 700 710 720 730 pF1KA0 LRAANKMGFGPFSEKCDITTAPGPPDQCKPPQVTCRSATCAQVNWEVPLSNGTDVTEYRL .:: : :.::.:. .:::: ::: ::: : ..: :. :.:: : :.:.:..:::: NP_001 VRALNDGGYGPYSDVSEITTAAGPPGQCKAPCISCTPDGCVLVGWESPDSSGADISEYRL 750 760 770 780 790 800 740 750 760 770 780 790 pF1KA0 EWGGVEGSMQICYCGPGLSYEIKGLSPATTYYCRVQALSVVGAGPFSEVVACVTPPSVPG ::: : :... : : .::. : ::. : ::.::.. .::::.::.: : :: :.: NP_001 EWGEDEESLELIYHGTDTRFEIRDLLPAAQYCCRLQAFNQAGAGPYSELVLCQTPASAPD 810 820 830 840 850 860 800 810 820 830 840 850 pF1KA0 IVTCLQEISDDEIENPHYSPSTCLAISWEKPCDHGSEILAYSIDFGDKQSLTVGKVTSYI :. : . .. .. :::.::...::.::..:::::::.::.:: :.:::..: .. NP_001 PVSTLCVLEEEPLDAYPDSPSACLVLNWEEPCNNGSEILAYTIDLGDT-SITVGNTTMHV 870 880 890 900 910 920 860 870 880 890 900 910 pF1KA0 INNLQPDTTYRIRIQALNSLGAGPFSHMIKLKTKPLPPDPPRLECVAFSHQNLKLKWGEG ...: :.:::::::::.: .::::::..:: ::.:::: ::::::.: . :.::::::.. NP_001 MKDLLPETTYRIRIQAINEIGAGPFSQFIKAKTRPLPPLPPRLECAAAGPQSLKLKWGDS 930 940 950 960 970 980 920 930 940 950 960 970 pF1KA0 TPKTLSTDSIQYHLQMEDKNGRFVSLYRGPCHTYKVQRLNESTSYKFCIQACNEAGEGPL . :: ....: : ::.::.: ::.:.:::: ::::::::.: : :.: ::: .::::::. NP_001 NSKTHAAEDIVYTLQLEDRNKRFISIYRGPSHTYKVQRLTEFTCYSFRIQAASEAGEGPF 990 1000 1010 1020 1030 1040 980 990 1000 1010 1020 1030 pF1KA0 SQEYIFTTPKSVPAALKAPKIEKVNDHICEITWECLQPMKGDPVIYSLQVMLGKDSEFKQ :. : :.: :::: ..:::.. ... . ::: :: . :::::: : :::..:..::.:: NP_001 SETYTFSTTKSVPPTIKAPRVTQLEGNSCEILWETVPSMKGDPVNYILQVLVGRESEYKQ 1050 1060 1070 1080 1090 1100 1040 1050 1060 1070 1080 1090 pF1KA0 IYKGPDSSFRYSSLQLNCEYRFRVCAIRQCQDSLGHQDLVGPYSTTVLFISQRTEPPAST .::: ...:. :.:: : .::::::: :.: :. :.: : .: .. :. ::.: . NP_001 VYKGEEATFQISGLQTNTDYRFRVCACRRCLDT--SQELSGAFSPSAAFVLQRSEVMLTG 1110 1120 1130 1140 1150 1100 1110 1120 1130 1140 pF1KA0 NRDTVESTRTRRAL-SDEQCAAVILVLFAFFSILIAFIIQYFVIK . .... . . . .::: ::.:.. :: .:::.:::.:::..: NP_001 DMGSLDDPKMKSMMPTDEQFAAIIVLGFATLSILFAFILQYFLMK 1160 1170 1180 1190 1200 1142 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 10:37:26 2016 done: Thu Nov 3 10:37:28 2016 Total Scan time: 14.660 Total Display time: 0.550 Function used was FASTA [36.3.4 Apr, 2011]