Result of FASTA (omim) for pF1KA0983
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA0983, 683 aa
  1>>>pF1KA0983 683 - 683 aa - 683 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.4284+/-0.000407; mu= 15.2740+/- 0.025
 mean_var=121.5232+/-24.300, 0's: 0 Z-trim(115.1): 34  B-trim: 0 in 0/56
 Lambda= 0.116344
 statistics sampled from 25359 (25390) to 25359 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.653), E-opt: 0.2 (0.298), width:  16
 Scan time: 11.090

The best scores are:                                      opt bits E(85289)
NP_003669 (OMIM: 612733) THO complex subunit 5 hom ( 683) 4559 777.0       0
NP_001002879 (OMIM: 612733) THO complex subunit 5  ( 683) 4559 777.0       0
NP_001002878 (OMIM: 612733) THO complex subunit 5  ( 683) 4559 777.0       0
NP_001002877 (OMIM: 612733) THO complex subunit 5  ( 683) 4559 777.0       0
XP_006724410 (OMIM: 612733) PREDICTED: THO complex ( 694) 2701 465.2 3.8e-130
XP_005261854 (OMIM: 612733) PREDICTED: THO complex ( 694) 2701 465.2 3.8e-130
XP_005261855 (OMIM: 612733) PREDICTED: THO complex ( 694) 2701 465.2 3.8e-130
XP_005261856 (OMIM: 612733) PREDICTED: THO complex ( 694) 2701 465.2 3.8e-130
XP_016884516 (OMIM: 612733) PREDICTED: THO complex ( 694) 2701 465.2 3.8e-130
XP_005261858 (OMIM: 612733) PREDICTED: THO complex ( 344) 2337 403.8 5.5e-112


>>NP_003669 (OMIM: 612733) THO complex subunit 5 homolog  (683 aa)
 initn: 4559 init1: 4559 opt: 4559  Z-score: 4143.1  bits: 777.0 E(85289):    0
Smith-Waterman score: 4559; 99.9% identity (100.0% similar) in 683 aa overlap (1-683:1-683)

               10        20        30        40        50        60
pF1KA0 MSSESSKKRKPKVIRSDGAPAEGKRNRSDTEQEGKYYSEEAEVDLRDPGRDYELYKYTCQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MSSESSKKRKPKVIRSDGAPAEGKRNRSDTEQEGKYYSEEAEVDLRDPGRDYELYKYTCQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 ELQRLMAEIQDLKSRGGKDVAIEIEERRIQSCVHFMTLKKLNRLAHIRLKKGRDQTHEAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ELQRLMAEIQDLKSRGGKDVAIEIEERRIQSCVHFMTLKKLNRLAHIRLKKGRDQTHEAK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 QKVDAYHLQLQNLLYEVMHLQKEITKCLEFKSKHEEIDLVSLEEFYKEAPPDISKAEVTM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QKVDAYHLQLQNLLYEVMHLQKEITKCLEFKSKHEEIDLVSLEEFYKEAPPDISKAEVTM
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 GDPHQQTLARLDWELEQRKRLAEKYRECLSNKEKILKEIEVKKEYLSSLQPRLNSIMQAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GDPHQQTLARLDWELEQRKRLAEKYRECLSNKEKILKEIEVKKEYLSSLQPRLNSIMQAS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 LPVQEYLFMPFDQAHKQYETARHLPPPLYVLFVQATAYGQACDKTLSVAIEGSVDEAKAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LPVQEYLFMPFDQAHKQYETARHLPPPLYVLFVQATAYGQACDKTLSVAIEGSVDEAKAL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 FKPPEDSQDDESDSDAEEEQTTKRRRPTLGVQLDDKRKEMLKRHPLSVMLDLKCKDDSVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 FKPPEDSQDDESDSDAEEEQTTKRRRPTLGVQLDDKRKEMLKRHPLSVMLDLKCKDDSVL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 HLTFYYLMNLNIMTVKAKVTTAMELITPISAGDLLSPDSVLSCLYPGDHGKKTPNPANQY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 HLTFYYLMNLNIMTVKAKVTTAMELITPISAGDLLSPDSVLSCLYPGDHGKKTPNPANQY
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 QFDKVGILTLSDYVLELGHPYLWVQKLGGLHFPKEQPQQTVIADHSLSASHMETTMKLLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QFDKVGILTLSDYVLELGHPYLWVQKLGGLHFPKEQPQQTVIADHSLSASHMETTMKLLK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 TRVQSRLALHKQFASLEHGIVPVTSDCQYLFPAKVVSRLVKWVTIAHEDYMELHFTKDIV
       ::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::
NP_003 TRVQSRLALHKQFASLEHGIVPVTSDCQYLFPAKVVSRLVKWVTVAHEDYMELHFTKDIV
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 DAGLAGDTNLYYMALIERGTAKLQAAVVLNPGYSSIPPVFQLCLNWKGEKTNSNDDNIRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DAGLAGDTNLYYMALIERGTAKLQAAVVLNPGYSSIPPVFQLCLNWKGEKTNSNDDNIRA
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 MEGEVNVCYKELCGPWPSHQLLTNQLQRLCVLLDVYLETESHDDSVEGPKEFPQEKMCLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MEGEVNVCYKELCGPWPSHQLLTNQLQRLCVLLDVYLETESHDDSVEGPKEFPQEKMCLR
              610       620       630       640       650       660

              670       680   
pF1KA0 LFRGPSRMKPFKYNHPQGFFSHR
       :::::::::::::::::::::::
NP_003 LFRGPSRMKPFKYNHPQGFFSHR
              670       680   

>>NP_001002879 (OMIM: 612733) THO complex subunit 5 homo  (683 aa)
 initn: 4559 init1: 4559 opt: 4559  Z-score: 4143.1  bits: 777.0 E(85289):    0
Smith-Waterman score: 4559; 99.9% identity (100.0% similar) in 683 aa overlap (1-683:1-683)

               10        20        30        40        50        60
pF1KA0 MSSESSKKRKPKVIRSDGAPAEGKRNRSDTEQEGKYYSEEAEVDLRDPGRDYELYKYTCQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSSESSKKRKPKVIRSDGAPAEGKRNRSDTEQEGKYYSEEAEVDLRDPGRDYELYKYTCQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 ELQRLMAEIQDLKSRGGKDVAIEIEERRIQSCVHFMTLKKLNRLAHIRLKKGRDQTHEAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELQRLMAEIQDLKSRGGKDVAIEIEERRIQSCVHFMTLKKLNRLAHIRLKKGRDQTHEAK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 QKVDAYHLQLQNLLYEVMHLQKEITKCLEFKSKHEEIDLVSLEEFYKEAPPDISKAEVTM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKVDAYHLQLQNLLYEVMHLQKEITKCLEFKSKHEEIDLVSLEEFYKEAPPDISKAEVTM
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 GDPHQQTLARLDWELEQRKRLAEKYRECLSNKEKILKEIEVKKEYLSSLQPRLNSIMQAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDPHQQTLARLDWELEQRKRLAEKYRECLSNKEKILKEIEVKKEYLSSLQPRLNSIMQAS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 LPVQEYLFMPFDQAHKQYETARHLPPPLYVLFVQATAYGQACDKTLSVAIEGSVDEAKAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPVQEYLFMPFDQAHKQYETARHLPPPLYVLFVQATAYGQACDKTLSVAIEGSVDEAKAL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 FKPPEDSQDDESDSDAEEEQTTKRRRPTLGVQLDDKRKEMLKRHPLSVMLDLKCKDDSVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FKPPEDSQDDESDSDAEEEQTTKRRRPTLGVQLDDKRKEMLKRHPLSVMLDLKCKDDSVL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 HLTFYYLMNLNIMTVKAKVTTAMELITPISAGDLLSPDSVLSCLYPGDHGKKTPNPANQY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLTFYYLMNLNIMTVKAKVTTAMELITPISAGDLLSPDSVLSCLYPGDHGKKTPNPANQY
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 QFDKVGILTLSDYVLELGHPYLWVQKLGGLHFPKEQPQQTVIADHSLSASHMETTMKLLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QFDKVGILTLSDYVLELGHPYLWVQKLGGLHFPKEQPQQTVIADHSLSASHMETTMKLLK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 TRVQSRLALHKQFASLEHGIVPVTSDCQYLFPAKVVSRLVKWVTIAHEDYMELHFTKDIV
       ::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::
NP_001 TRVQSRLALHKQFASLEHGIVPVTSDCQYLFPAKVVSRLVKWVTVAHEDYMELHFTKDIV
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 DAGLAGDTNLYYMALIERGTAKLQAAVVLNPGYSSIPPVFQLCLNWKGEKTNSNDDNIRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DAGLAGDTNLYYMALIERGTAKLQAAVVLNPGYSSIPPVFQLCLNWKGEKTNSNDDNIRA
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 MEGEVNVCYKELCGPWPSHQLLTNQLQRLCVLLDVYLETESHDDSVEGPKEFPQEKMCLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEGEVNVCYKELCGPWPSHQLLTNQLQRLCVLLDVYLETESHDDSVEGPKEFPQEKMCLR
              610       620       630       640       650       660

              670       680   
pF1KA0 LFRGPSRMKPFKYNHPQGFFSHR
       :::::::::::::::::::::::
NP_001 LFRGPSRMKPFKYNHPQGFFSHR
              670       680   

>>NP_001002878 (OMIM: 612733) THO complex subunit 5 homo  (683 aa)
 initn: 4559 init1: 4559 opt: 4559  Z-score: 4143.1  bits: 777.0 E(85289):    0
Smith-Waterman score: 4559; 99.9% identity (100.0% similar) in 683 aa overlap (1-683:1-683)

               10        20        30        40        50        60
pF1KA0 MSSESSKKRKPKVIRSDGAPAEGKRNRSDTEQEGKYYSEEAEVDLRDPGRDYELYKYTCQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSSESSKKRKPKVIRSDGAPAEGKRNRSDTEQEGKYYSEEAEVDLRDPGRDYELYKYTCQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 ELQRLMAEIQDLKSRGGKDVAIEIEERRIQSCVHFMTLKKLNRLAHIRLKKGRDQTHEAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELQRLMAEIQDLKSRGGKDVAIEIEERRIQSCVHFMTLKKLNRLAHIRLKKGRDQTHEAK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 QKVDAYHLQLQNLLYEVMHLQKEITKCLEFKSKHEEIDLVSLEEFYKEAPPDISKAEVTM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKVDAYHLQLQNLLYEVMHLQKEITKCLEFKSKHEEIDLVSLEEFYKEAPPDISKAEVTM
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 GDPHQQTLARLDWELEQRKRLAEKYRECLSNKEKILKEIEVKKEYLSSLQPRLNSIMQAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDPHQQTLARLDWELEQRKRLAEKYRECLSNKEKILKEIEVKKEYLSSLQPRLNSIMQAS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 LPVQEYLFMPFDQAHKQYETARHLPPPLYVLFVQATAYGQACDKTLSVAIEGSVDEAKAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPVQEYLFMPFDQAHKQYETARHLPPPLYVLFVQATAYGQACDKTLSVAIEGSVDEAKAL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 FKPPEDSQDDESDSDAEEEQTTKRRRPTLGVQLDDKRKEMLKRHPLSVMLDLKCKDDSVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FKPPEDSQDDESDSDAEEEQTTKRRRPTLGVQLDDKRKEMLKRHPLSVMLDLKCKDDSVL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 HLTFYYLMNLNIMTVKAKVTTAMELITPISAGDLLSPDSVLSCLYPGDHGKKTPNPANQY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLTFYYLMNLNIMTVKAKVTTAMELITPISAGDLLSPDSVLSCLYPGDHGKKTPNPANQY
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 QFDKVGILTLSDYVLELGHPYLWVQKLGGLHFPKEQPQQTVIADHSLSASHMETTMKLLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QFDKVGILTLSDYVLELGHPYLWVQKLGGLHFPKEQPQQTVIADHSLSASHMETTMKLLK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 TRVQSRLALHKQFASLEHGIVPVTSDCQYLFPAKVVSRLVKWVTIAHEDYMELHFTKDIV
       ::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::
NP_001 TRVQSRLALHKQFASLEHGIVPVTSDCQYLFPAKVVSRLVKWVTVAHEDYMELHFTKDIV
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 DAGLAGDTNLYYMALIERGTAKLQAAVVLNPGYSSIPPVFQLCLNWKGEKTNSNDDNIRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DAGLAGDTNLYYMALIERGTAKLQAAVVLNPGYSSIPPVFQLCLNWKGEKTNSNDDNIRA
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 MEGEVNVCYKELCGPWPSHQLLTNQLQRLCVLLDVYLETESHDDSVEGPKEFPQEKMCLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEGEVNVCYKELCGPWPSHQLLTNQLQRLCVLLDVYLETESHDDSVEGPKEFPQEKMCLR
              610       620       630       640       650       660

              670       680   
pF1KA0 LFRGPSRMKPFKYNHPQGFFSHR
       :::::::::::::::::::::::
NP_001 LFRGPSRMKPFKYNHPQGFFSHR
              670       680   

>>NP_001002877 (OMIM: 612733) THO complex subunit 5 homo  (683 aa)
 initn: 4559 init1: 4559 opt: 4559  Z-score: 4143.1  bits: 777.0 E(85289):    0
Smith-Waterman score: 4559; 99.9% identity (100.0% similar) in 683 aa overlap (1-683:1-683)

               10        20        30        40        50        60
pF1KA0 MSSESSKKRKPKVIRSDGAPAEGKRNRSDTEQEGKYYSEEAEVDLRDPGRDYELYKYTCQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSSESSKKRKPKVIRSDGAPAEGKRNRSDTEQEGKYYSEEAEVDLRDPGRDYELYKYTCQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 ELQRLMAEIQDLKSRGGKDVAIEIEERRIQSCVHFMTLKKLNRLAHIRLKKGRDQTHEAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELQRLMAEIQDLKSRGGKDVAIEIEERRIQSCVHFMTLKKLNRLAHIRLKKGRDQTHEAK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 QKVDAYHLQLQNLLYEVMHLQKEITKCLEFKSKHEEIDLVSLEEFYKEAPPDISKAEVTM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKVDAYHLQLQNLLYEVMHLQKEITKCLEFKSKHEEIDLVSLEEFYKEAPPDISKAEVTM
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 GDPHQQTLARLDWELEQRKRLAEKYRECLSNKEKILKEIEVKKEYLSSLQPRLNSIMQAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDPHQQTLARLDWELEQRKRLAEKYRECLSNKEKILKEIEVKKEYLSSLQPRLNSIMQAS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 LPVQEYLFMPFDQAHKQYETARHLPPPLYVLFVQATAYGQACDKTLSVAIEGSVDEAKAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPVQEYLFMPFDQAHKQYETARHLPPPLYVLFVQATAYGQACDKTLSVAIEGSVDEAKAL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 FKPPEDSQDDESDSDAEEEQTTKRRRPTLGVQLDDKRKEMLKRHPLSVMLDLKCKDDSVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FKPPEDSQDDESDSDAEEEQTTKRRRPTLGVQLDDKRKEMLKRHPLSVMLDLKCKDDSVL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 HLTFYYLMNLNIMTVKAKVTTAMELITPISAGDLLSPDSVLSCLYPGDHGKKTPNPANQY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLTFYYLMNLNIMTVKAKVTTAMELITPISAGDLLSPDSVLSCLYPGDHGKKTPNPANQY
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 QFDKVGILTLSDYVLELGHPYLWVQKLGGLHFPKEQPQQTVIADHSLSASHMETTMKLLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QFDKVGILTLSDYVLELGHPYLWVQKLGGLHFPKEQPQQTVIADHSLSASHMETTMKLLK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 TRVQSRLALHKQFASLEHGIVPVTSDCQYLFPAKVVSRLVKWVTIAHEDYMELHFTKDIV
       ::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::
NP_001 TRVQSRLALHKQFASLEHGIVPVTSDCQYLFPAKVVSRLVKWVTVAHEDYMELHFTKDIV
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 DAGLAGDTNLYYMALIERGTAKLQAAVVLNPGYSSIPPVFQLCLNWKGEKTNSNDDNIRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DAGLAGDTNLYYMALIERGTAKLQAAVVLNPGYSSIPPVFQLCLNWKGEKTNSNDDNIRA
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 MEGEVNVCYKELCGPWPSHQLLTNQLQRLCVLLDVYLETESHDDSVEGPKEFPQEKMCLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEGEVNVCYKELCGPWPSHQLLTNQLQRLCVLLDVYLETESHDDSVEGPKEFPQEKMCLR
              610       620       630       640       650       660

              670       680   
pF1KA0 LFRGPSRMKPFKYNHPQGFFSHR
       :::::::::::::::::::::::
NP_001 LFRGPSRMKPFKYNHPQGFFSHR
              670       680   

>>XP_006724410 (OMIM: 612733) PREDICTED: THO complex sub  (694 aa)
 initn: 4545 init1: 2701 opt: 2701  Z-score: 2457.6  bits: 465.2 E(85289): 3.8e-130
Smith-Waterman score: 4527; 98.3% identity (98.4% similar) in 694 aa overlap (1-683:1-694)

               10        20        30        40        50        60
pF1KA0 MSSESSKKRKPKVIRSDGAPAEGKRNRSDTEQEGKYYSEEAEVDLRDPGRDYELYKYTCQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MSSESSKKRKPKVIRSDGAPAEGKRNRSDTEQEGKYYSEEAEVDLRDPGRDYELYKYTCQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 ELQRLMAEIQDLKSRGGKDVAIEIEERRIQSCVHFMTLKKLNRLAHIRLKKGRDQTHEAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELQRLMAEIQDLKSRGGKDVAIEIEERRIQSCVHFMTLKKLNRLAHIRLKKGRDQTHEAK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 QKVDAYHLQLQNLLYEVMHLQKEITKCLEFKSKHEEIDLVSLEEFYKEAPPDISKAEVTM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QKVDAYHLQLQNLLYEVMHLQKEITKCLEFKSKHEEIDLVSLEEFYKEAPPDISKAEVTM
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 GDPHQQTLARLDWELEQRKRLAEKYRECLSNKEKILKEIEVKKEYLSSLQPRLNSIMQAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GDPHQQTLARLDWELEQRKRLAEKYRECLSNKEKILKEIEVKKEYLSSLQPRLNSIMQAS
              190       200       210       220       230       240

              250       260       270       280                    
pF1KA0 LPVQEYLFMPFDQAHKQYETARHLPPPLYVLFVQATAYGQAC-----------DKTLSVA
       ::::::::::::::::::::::::::::::::::::::::::           :::::::
XP_006 LPVQEYLFMPFDQAHKQYETARHLPPPLYVLFVQATAYGQACAHMKSSQPPRQDKTLSVA
              250       260       270       280       290       300

     290       300       310       320       330       340         
pF1KA0 IEGSVDEAKALFKPPEDSQDDESDSDAEEEQTTKRRRPTLGVQLDDKRKEMLKRHPLSVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IEGSVDEAKALFKPPEDSQDDESDSDAEEEQTTKRRRPTLGVQLDDKRKEMLKRHPLSVM
              310       320       330       340       350       360

     350       360       370       380       390       400         
pF1KA0 LDLKCKDDSVLHLTFYYLMNLNIMTVKAKVTTAMELITPISAGDLLSPDSVLSCLYPGDH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LDLKCKDDSVLHLTFYYLMNLNIMTVKAKVTTAMELITPISAGDLLSPDSVLSCLYPGDH
              370       380       390       400       410       420

     410       420       430       440       450       460         
pF1KA0 GKKTPNPANQYQFDKVGILTLSDYVLELGHPYLWVQKLGGLHFPKEQPQQTVIADHSLSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GKKTPNPANQYQFDKVGILTLSDYVLELGHPYLWVQKLGGLHFPKEQPQQTVIADHSLSA
              430       440       450       460       470       480

     470       480       490       500       510       520         
pF1KA0 SHMETTMKLLKTRVQSRLALHKQFASLEHGIVPVTSDCQYLFPAKVVSRLVKWVTIAHED
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::
XP_006 SHMETTMKLLKTRVQSRLALHKQFASLEHGIVPVTSDCQYLFPAKVVSRLVKWVTVAHED
              490       500       510       520       530       540

     530       540       550       560       570       580         
pF1KA0 YMELHFTKDIVDAGLAGDTNLYYMALIERGTAKLQAAVVLNPGYSSIPPVFQLCLNWKGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YMELHFTKDIVDAGLAGDTNLYYMALIERGTAKLQAAVVLNPGYSSIPPVFQLCLNWKGE
              550       560       570       580       590       600

     590       600       610       620       630       640         
pF1KA0 KTNSNDDNIRAMEGEVNVCYKELCGPWPSHQLLTNQLQRLCVLLDVYLETESHDDSVEGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KTNSNDDNIRAMEGEVNVCYKELCGPWPSHQLLTNQLQRLCVLLDVYLETESHDDSVEGP
              610       620       630       640       650       660

     650       660       670       680   
pF1KA0 KEFPQEKMCLRLFRGPSRMKPFKYNHPQGFFSHR
       ::::::::::::::::::::::::::::::::::
XP_006 KEFPQEKMCLRLFRGPSRMKPFKYNHPQGFFSHR
              670       680       690    

>>XP_005261854 (OMIM: 612733) PREDICTED: THO complex sub  (694 aa)
 initn: 4545 init1: 2701 opt: 2701  Z-score: 2457.6  bits: 465.2 E(85289): 3.8e-130
Smith-Waterman score: 4527; 98.3% identity (98.4% similar) in 694 aa overlap (1-683:1-694)

               10        20        30        40        50        60
pF1KA0 MSSESSKKRKPKVIRSDGAPAEGKRNRSDTEQEGKYYSEEAEVDLRDPGRDYELYKYTCQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSSESSKKRKPKVIRSDGAPAEGKRNRSDTEQEGKYYSEEAEVDLRDPGRDYELYKYTCQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 ELQRLMAEIQDLKSRGGKDVAIEIEERRIQSCVHFMTLKKLNRLAHIRLKKGRDQTHEAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELQRLMAEIQDLKSRGGKDVAIEIEERRIQSCVHFMTLKKLNRLAHIRLKKGRDQTHEAK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 QKVDAYHLQLQNLLYEVMHLQKEITKCLEFKSKHEEIDLVSLEEFYKEAPPDISKAEVTM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QKVDAYHLQLQNLLYEVMHLQKEITKCLEFKSKHEEIDLVSLEEFYKEAPPDISKAEVTM
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 GDPHQQTLARLDWELEQRKRLAEKYRECLSNKEKILKEIEVKKEYLSSLQPRLNSIMQAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GDPHQQTLARLDWELEQRKRLAEKYRECLSNKEKILKEIEVKKEYLSSLQPRLNSIMQAS
              190       200       210       220       230       240

              250       260       270       280                    
pF1KA0 LPVQEYLFMPFDQAHKQYETARHLPPPLYVLFVQATAYGQAC-----------DKTLSVA
       ::::::::::::::::::::::::::::::::::::::::::           :::::::
XP_005 LPVQEYLFMPFDQAHKQYETARHLPPPLYVLFVQATAYGQACAHMKSSQPPRQDKTLSVA
              250       260       270       280       290       300

     290       300       310       320       330       340         
pF1KA0 IEGSVDEAKALFKPPEDSQDDESDSDAEEEQTTKRRRPTLGVQLDDKRKEMLKRHPLSVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IEGSVDEAKALFKPPEDSQDDESDSDAEEEQTTKRRRPTLGVQLDDKRKEMLKRHPLSVM
              310       320       330       340       350       360

     350       360       370       380       390       400         
pF1KA0 LDLKCKDDSVLHLTFYYLMNLNIMTVKAKVTTAMELITPISAGDLLSPDSVLSCLYPGDH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDLKCKDDSVLHLTFYYLMNLNIMTVKAKVTTAMELITPISAGDLLSPDSVLSCLYPGDH
              370       380       390       400       410       420

     410       420       430       440       450       460         
pF1KA0 GKKTPNPANQYQFDKVGILTLSDYVLELGHPYLWVQKLGGLHFPKEQPQQTVIADHSLSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GKKTPNPANQYQFDKVGILTLSDYVLELGHPYLWVQKLGGLHFPKEQPQQTVIADHSLSA
              430       440       450       460       470       480

     470       480       490       500       510       520         
pF1KA0 SHMETTMKLLKTRVQSRLALHKQFASLEHGIVPVTSDCQYLFPAKVVSRLVKWVTIAHED
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::
XP_005 SHMETTMKLLKTRVQSRLALHKQFASLEHGIVPVTSDCQYLFPAKVVSRLVKWVTVAHED
              490       500       510       520       530       540

     530       540       550       560       570       580         
pF1KA0 YMELHFTKDIVDAGLAGDTNLYYMALIERGTAKLQAAVVLNPGYSSIPPVFQLCLNWKGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YMELHFTKDIVDAGLAGDTNLYYMALIERGTAKLQAAVVLNPGYSSIPPVFQLCLNWKGE
              550       560       570       580       590       600

     590       600       610       620       630       640         
pF1KA0 KTNSNDDNIRAMEGEVNVCYKELCGPWPSHQLLTNQLQRLCVLLDVYLETESHDDSVEGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KTNSNDDNIRAMEGEVNVCYKELCGPWPSHQLLTNQLQRLCVLLDVYLETESHDDSVEGP
              610       620       630       640       650       660

     650       660       670       680   
pF1KA0 KEFPQEKMCLRLFRGPSRMKPFKYNHPQGFFSHR
       ::::::::::::::::::::::::::::::::::
XP_005 KEFPQEKMCLRLFRGPSRMKPFKYNHPQGFFSHR
              670       680       690    

>>XP_005261855 (OMIM: 612733) PREDICTED: THO complex sub  (694 aa)
 initn: 4545 init1: 2701 opt: 2701  Z-score: 2457.6  bits: 465.2 E(85289): 3.8e-130
Smith-Waterman score: 4527; 98.3% identity (98.4% similar) in 694 aa overlap (1-683:1-694)

               10        20        30        40        50        60
pF1KA0 MSSESSKKRKPKVIRSDGAPAEGKRNRSDTEQEGKYYSEEAEVDLRDPGRDYELYKYTCQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSSESSKKRKPKVIRSDGAPAEGKRNRSDTEQEGKYYSEEAEVDLRDPGRDYELYKYTCQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 ELQRLMAEIQDLKSRGGKDVAIEIEERRIQSCVHFMTLKKLNRLAHIRLKKGRDQTHEAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELQRLMAEIQDLKSRGGKDVAIEIEERRIQSCVHFMTLKKLNRLAHIRLKKGRDQTHEAK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 QKVDAYHLQLQNLLYEVMHLQKEITKCLEFKSKHEEIDLVSLEEFYKEAPPDISKAEVTM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QKVDAYHLQLQNLLYEVMHLQKEITKCLEFKSKHEEIDLVSLEEFYKEAPPDISKAEVTM
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 GDPHQQTLARLDWELEQRKRLAEKYRECLSNKEKILKEIEVKKEYLSSLQPRLNSIMQAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GDPHQQTLARLDWELEQRKRLAEKYRECLSNKEKILKEIEVKKEYLSSLQPRLNSIMQAS
              190       200       210       220       230       240

              250       260       270       280                    
pF1KA0 LPVQEYLFMPFDQAHKQYETARHLPPPLYVLFVQATAYGQAC-----------DKTLSVA
       ::::::::::::::::::::::::::::::::::::::::::           :::::::
XP_005 LPVQEYLFMPFDQAHKQYETARHLPPPLYVLFVQATAYGQACAHMKSSQPPRQDKTLSVA
              250       260       270       280       290       300

     290       300       310       320       330       340         
pF1KA0 IEGSVDEAKALFKPPEDSQDDESDSDAEEEQTTKRRRPTLGVQLDDKRKEMLKRHPLSVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IEGSVDEAKALFKPPEDSQDDESDSDAEEEQTTKRRRPTLGVQLDDKRKEMLKRHPLSVM
              310       320       330       340       350       360

     350       360       370       380       390       400         
pF1KA0 LDLKCKDDSVLHLTFYYLMNLNIMTVKAKVTTAMELITPISAGDLLSPDSVLSCLYPGDH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDLKCKDDSVLHLTFYYLMNLNIMTVKAKVTTAMELITPISAGDLLSPDSVLSCLYPGDH
              370       380       390       400       410       420

     410       420       430       440       450       460         
pF1KA0 GKKTPNPANQYQFDKVGILTLSDYVLELGHPYLWVQKLGGLHFPKEQPQQTVIADHSLSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GKKTPNPANQYQFDKVGILTLSDYVLELGHPYLWVQKLGGLHFPKEQPQQTVIADHSLSA
              430       440       450       460       470       480

     470       480       490       500       510       520         
pF1KA0 SHMETTMKLLKTRVQSRLALHKQFASLEHGIVPVTSDCQYLFPAKVVSRLVKWVTIAHED
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::
XP_005 SHMETTMKLLKTRVQSRLALHKQFASLEHGIVPVTSDCQYLFPAKVVSRLVKWVTVAHED
              490       500       510       520       530       540

     530       540       550       560       570       580         
pF1KA0 YMELHFTKDIVDAGLAGDTNLYYMALIERGTAKLQAAVVLNPGYSSIPPVFQLCLNWKGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YMELHFTKDIVDAGLAGDTNLYYMALIERGTAKLQAAVVLNPGYSSIPPVFQLCLNWKGE
              550       560       570       580       590       600

     590       600       610       620       630       640         
pF1KA0 KTNSNDDNIRAMEGEVNVCYKELCGPWPSHQLLTNQLQRLCVLLDVYLETESHDDSVEGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KTNSNDDNIRAMEGEVNVCYKELCGPWPSHQLLTNQLQRLCVLLDVYLETESHDDSVEGP
              610       620       630       640       650       660

     650       660       670       680   
pF1KA0 KEFPQEKMCLRLFRGPSRMKPFKYNHPQGFFSHR
       ::::::::::::::::::::::::::::::::::
XP_005 KEFPQEKMCLRLFRGPSRMKPFKYNHPQGFFSHR
              670       680       690    

>>XP_005261856 (OMIM: 612733) PREDICTED: THO complex sub  (694 aa)
 initn: 4545 init1: 2701 opt: 2701  Z-score: 2457.6  bits: 465.2 E(85289): 3.8e-130
Smith-Waterman score: 4527; 98.3% identity (98.4% similar) in 694 aa overlap (1-683:1-694)

               10        20        30        40        50        60
pF1KA0 MSSESSKKRKPKVIRSDGAPAEGKRNRSDTEQEGKYYSEEAEVDLRDPGRDYELYKYTCQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSSESSKKRKPKVIRSDGAPAEGKRNRSDTEQEGKYYSEEAEVDLRDPGRDYELYKYTCQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 ELQRLMAEIQDLKSRGGKDVAIEIEERRIQSCVHFMTLKKLNRLAHIRLKKGRDQTHEAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELQRLMAEIQDLKSRGGKDVAIEIEERRIQSCVHFMTLKKLNRLAHIRLKKGRDQTHEAK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 QKVDAYHLQLQNLLYEVMHLQKEITKCLEFKSKHEEIDLVSLEEFYKEAPPDISKAEVTM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QKVDAYHLQLQNLLYEVMHLQKEITKCLEFKSKHEEIDLVSLEEFYKEAPPDISKAEVTM
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 GDPHQQTLARLDWELEQRKRLAEKYRECLSNKEKILKEIEVKKEYLSSLQPRLNSIMQAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GDPHQQTLARLDWELEQRKRLAEKYRECLSNKEKILKEIEVKKEYLSSLQPRLNSIMQAS
              190       200       210       220       230       240

              250       260       270       280                    
pF1KA0 LPVQEYLFMPFDQAHKQYETARHLPPPLYVLFVQATAYGQAC-----------DKTLSVA
       ::::::::::::::::::::::::::::::::::::::::::           :::::::
XP_005 LPVQEYLFMPFDQAHKQYETARHLPPPLYVLFVQATAYGQACAHMKSSQPPRQDKTLSVA
              250       260       270       280       290       300

     290       300       310       320       330       340         
pF1KA0 IEGSVDEAKALFKPPEDSQDDESDSDAEEEQTTKRRRPTLGVQLDDKRKEMLKRHPLSVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IEGSVDEAKALFKPPEDSQDDESDSDAEEEQTTKRRRPTLGVQLDDKRKEMLKRHPLSVM
              310       320       330       340       350       360

     350       360       370       380       390       400         
pF1KA0 LDLKCKDDSVLHLTFYYLMNLNIMTVKAKVTTAMELITPISAGDLLSPDSVLSCLYPGDH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDLKCKDDSVLHLTFYYLMNLNIMTVKAKVTTAMELITPISAGDLLSPDSVLSCLYPGDH
              370       380       390       400       410       420

     410       420       430       440       450       460         
pF1KA0 GKKTPNPANQYQFDKVGILTLSDYVLELGHPYLWVQKLGGLHFPKEQPQQTVIADHSLSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GKKTPNPANQYQFDKVGILTLSDYVLELGHPYLWVQKLGGLHFPKEQPQQTVIADHSLSA
              430       440       450       460       470       480

     470       480       490       500       510       520         
pF1KA0 SHMETTMKLLKTRVQSRLALHKQFASLEHGIVPVTSDCQYLFPAKVVSRLVKWVTIAHED
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::
XP_005 SHMETTMKLLKTRVQSRLALHKQFASLEHGIVPVTSDCQYLFPAKVVSRLVKWVTVAHED
              490       500       510       520       530       540

     530       540       550       560       570       580         
pF1KA0 YMELHFTKDIVDAGLAGDTNLYYMALIERGTAKLQAAVVLNPGYSSIPPVFQLCLNWKGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YMELHFTKDIVDAGLAGDTNLYYMALIERGTAKLQAAVVLNPGYSSIPPVFQLCLNWKGE
              550       560       570       580       590       600

     590       600       610       620       630       640         
pF1KA0 KTNSNDDNIRAMEGEVNVCYKELCGPWPSHQLLTNQLQRLCVLLDVYLETESHDDSVEGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KTNSNDDNIRAMEGEVNVCYKELCGPWPSHQLLTNQLQRLCVLLDVYLETESHDDSVEGP
              610       620       630       640       650       660

     650       660       670       680   
pF1KA0 KEFPQEKMCLRLFRGPSRMKPFKYNHPQGFFSHR
       ::::::::::::::::::::::::::::::::::
XP_005 KEFPQEKMCLRLFRGPSRMKPFKYNHPQGFFSHR
              670       680       690    

>>XP_016884516 (OMIM: 612733) PREDICTED: THO complex sub  (694 aa)
 initn: 4545 init1: 2701 opt: 2701  Z-score: 2457.6  bits: 465.2 E(85289): 3.8e-130
Smith-Waterman score: 4527; 98.3% identity (98.4% similar) in 694 aa overlap (1-683:1-694)

               10        20        30        40        50        60
pF1KA0 MSSESSKKRKPKVIRSDGAPAEGKRNRSDTEQEGKYYSEEAEVDLRDPGRDYELYKYTCQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSSESSKKRKPKVIRSDGAPAEGKRNRSDTEQEGKYYSEEAEVDLRDPGRDYELYKYTCQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 ELQRLMAEIQDLKSRGGKDVAIEIEERRIQSCVHFMTLKKLNRLAHIRLKKGRDQTHEAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELQRLMAEIQDLKSRGGKDVAIEIEERRIQSCVHFMTLKKLNRLAHIRLKKGRDQTHEAK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 QKVDAYHLQLQNLLYEVMHLQKEITKCLEFKSKHEEIDLVSLEEFYKEAPPDISKAEVTM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKVDAYHLQLQNLLYEVMHLQKEITKCLEFKSKHEEIDLVSLEEFYKEAPPDISKAEVTM
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 GDPHQQTLARLDWELEQRKRLAEKYRECLSNKEKILKEIEVKKEYLSSLQPRLNSIMQAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDPHQQTLARLDWELEQRKRLAEKYRECLSNKEKILKEIEVKKEYLSSLQPRLNSIMQAS
              190       200       210       220       230       240

              250       260       270       280                    
pF1KA0 LPVQEYLFMPFDQAHKQYETARHLPPPLYVLFVQATAYGQAC-----------DKTLSVA
       ::::::::::::::::::::::::::::::::::::::::::           :::::::
XP_016 LPVQEYLFMPFDQAHKQYETARHLPPPLYVLFVQATAYGQACAHMKSSQPPRQDKTLSVA
              250       260       270       280       290       300

     290       300       310       320       330       340         
pF1KA0 IEGSVDEAKALFKPPEDSQDDESDSDAEEEQTTKRRRPTLGVQLDDKRKEMLKRHPLSVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEGSVDEAKALFKPPEDSQDDESDSDAEEEQTTKRRRPTLGVQLDDKRKEMLKRHPLSVM
              310       320       330       340       350       360

     350       360       370       380       390       400         
pF1KA0 LDLKCKDDSVLHLTFYYLMNLNIMTVKAKVTTAMELITPISAGDLLSPDSVLSCLYPGDH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDLKCKDDSVLHLTFYYLMNLNIMTVKAKVTTAMELITPISAGDLLSPDSVLSCLYPGDH
              370       380       390       400       410       420

     410       420       430       440       450       460         
pF1KA0 GKKTPNPANQYQFDKVGILTLSDYVLELGHPYLWVQKLGGLHFPKEQPQQTVIADHSLSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKKTPNPANQYQFDKVGILTLSDYVLELGHPYLWVQKLGGLHFPKEQPQQTVIADHSLSA
              430       440       450       460       470       480

     470       480       490       500       510       520         
pF1KA0 SHMETTMKLLKTRVQSRLALHKQFASLEHGIVPVTSDCQYLFPAKVVSRLVKWVTIAHED
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::
XP_016 SHMETTMKLLKTRVQSRLALHKQFASLEHGIVPVTSDCQYLFPAKVVSRLVKWVTVAHED
              490       500       510       520       530       540

     530       540       550       560       570       580         
pF1KA0 YMELHFTKDIVDAGLAGDTNLYYMALIERGTAKLQAAVVLNPGYSSIPPVFQLCLNWKGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YMELHFTKDIVDAGLAGDTNLYYMALIERGTAKLQAAVVLNPGYSSIPPVFQLCLNWKGE
              550       560       570       580       590       600

     590       600       610       620       630       640         
pF1KA0 KTNSNDDNIRAMEGEVNVCYKELCGPWPSHQLLTNQLQRLCVLLDVYLETESHDDSVEGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTNSNDDNIRAMEGEVNVCYKELCGPWPSHQLLTNQLQRLCVLLDVYLETESHDDSVEGP
              610       620       630       640       650       660

     650       660       670       680   
pF1KA0 KEFPQEKMCLRLFRGPSRMKPFKYNHPQGFFSHR
       ::::::::::::::::::::::::::::::::::
XP_016 KEFPQEKMCLRLFRGPSRMKPFKYNHPQGFFSHR
              670       680       690    

>>XP_005261858 (OMIM: 612733) PREDICTED: THO complex sub  (344 aa)
 initn: 2337 init1: 2337 opt: 2337  Z-score: 2131.5  bits: 403.8 E(85289): 5.5e-112
Smith-Waterman score: 2337; 99.7% identity (100.0% similar) in 344 aa overlap (340-683:1-344)

     310       320       330       340       350       360         
pF1KA0 DESDSDAEEEQTTKRRRPTLGVQLDDKRKEMLKRHPLSVMLDLKCKDDSVLHLTFYYLMN
                                     ::::::::::::::::::::::::::::::
XP_005                               MLKRHPLSVMLDLKCKDDSVLHLTFYYLMN
                                             10        20        30

     370       380       390       400       410       420         
pF1KA0 LNIMTVKAKVTTAMELITPISAGDLLSPDSVLSCLYPGDHGKKTPNPANQYQFDKVGILT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LNIMTVKAKVTTAMELITPISAGDLLSPDSVLSCLYPGDHGKKTPNPANQYQFDKVGILT
               40        50        60        70        80        90

     430       440       450       460       470       480         
pF1KA0 LSDYVLELGHPYLWVQKLGGLHFPKEQPQQTVIADHSLSASHMETTMKLLKTRVQSRLAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSDYVLELGHPYLWVQKLGGLHFPKEQPQQTVIADHSLSASHMETTMKLLKTRVQSRLAL
              100       110       120       130       140       150

     490       500       510       520       530       540         
pF1KA0 HKQFASLEHGIVPVTSDCQYLFPAKVVSRLVKWVTIAHEDYMELHFTKDIVDAGLAGDTN
       :::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::
XP_005 HKQFASLEHGIVPVTSDCQYLFPAKVVSRLVKWVTVAHEDYMELHFTKDIVDAGLAGDTN
              160       170       180       190       200       210

     550       560       570       580       590       600         
pF1KA0 LYYMALIERGTAKLQAAVVLNPGYSSIPPVFQLCLNWKGEKTNSNDDNIRAMEGEVNVCY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LYYMALIERGTAKLQAAVVLNPGYSSIPPVFQLCLNWKGEKTNSNDDNIRAMEGEVNVCY
              220       230       240       250       260       270

     610       620       630       640       650       660         
pF1KA0 KELCGPWPSHQLLTNQLQRLCVLLDVYLETESHDDSVEGPKEFPQEKMCLRLFRGPSRMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KELCGPWPSHQLLTNQLQRLCVLLDVYLETESHDDSVEGPKEFPQEKMCLRLFRGPSRMK
              280       290       300       310       320       330

     670       680   
pF1KA0 PFKYNHPQGFFSHR
       ::::::::::::::
XP_005 PFKYNHPQGFFSHR
              340    




683 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 01:14:11 2016 done: Fri Nov  4 01:14:12 2016
 Total Scan time: 11.090 Total Display time:  0.160

Function used was FASTA [36.3.4 Apr, 2011]
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