FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA0985, 694 aa 1>>>pF1KA0985 694 - 694 aa - 694 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 14.5430+/-0.000476; mu= -21.4936+/- 0.030 mean_var=603.1288+/-126.001, 0's: 0 Z-trim(124.5): 166 B-trim: 966 in 2/58 Lambda= 0.052224 statistics sampled from 46071 (46269) to 46071 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.81), E-opt: 0.2 (0.542), width: 16 Scan time: 12.060 The best scores are: opt bits E(85289) XP_011536350 (OMIM: 612159) PREDICTED: rabphilin-3 ( 694) 4813 377.7 8.4e-104 NP_001137326 (OMIM: 612159) rabphilin-3A isoform 1 ( 694) 4813 377.7 8.4e-104 NP_055769 (OMIM: 612159) rabphilin-3A isoform 2 [H ( 690) 4763 373.9 1.1e-102 XP_016874523 (OMIM: 612159) PREDICTED: rabphilin-3 ( 346) 2334 190.7 8.3e-48 XP_016879265 (OMIM: 604567) PREDICTED: double C2-l ( 400) 1402 120.5 1.3e-26 XP_016879266 (OMIM: 604567) PREDICTED: double C2-l ( 400) 1402 120.5 1.3e-26 NP_001268997 (OMIM: 604567) double C2-like domain- ( 400) 1402 120.5 1.3e-26 NP_003577 (OMIM: 604567) double C2-like domain-con ( 400) 1402 120.5 1.3e-26 NP_001268992 (OMIM: 604567) double C2-like domain- ( 400) 1402 120.5 1.3e-26 NP_001268991 (OMIM: 604567) double C2-like domain- ( 400) 1402 120.5 1.3e-26 XP_011544277 (OMIM: 604567) PREDICTED: double C2-l ( 400) 1402 120.5 1.3e-26 XP_016879267 (OMIM: 604567) PREDICTED: double C2-l ( 282) 1200 105.1 3.7e-22 XP_016880716 (OMIM: 604568) PREDICTED: double C2-l ( 340) 891 81.9 4.4e-15 NP_003576 (OMIM: 604568) double C2-like domain-con ( 412) 890 81.9 5.3e-15 XP_011533665 (OMIM: 604568) PREDICTED: double C2-l ( 387) 788 74.2 1e-12 XP_011533666 (OMIM: 604881) PREDICTED: rab effecto ( 321) 750 71.3 6.6e-12 XP_011533667 (OMIM: 604881) PREDICTED: rab effecto ( 321) 750 71.3 6.6e-12 XP_011533668 (OMIM: 604881) PREDICTED: rab effecto ( 321) 750 71.3 6.6e-12 NP_008918 (OMIM: 604881) rab effector Noc2 isoform ( 315) 746 71.0 8e-12 XP_011533669 (OMIM: 604881) PREDICTED: rab effecto ( 315) 746 71.0 8e-12 NP_001177340 (OMIM: 604881) rab effector Noc2 isof ( 315) 746 71.0 8e-12 XP_016880857 (OMIM: 604881) PREDICTED: rab effecto ( 253) 718 68.8 2.9e-11 XP_016880856 (OMIM: 604881) PREDICTED: rab effecto ( 259) 696 67.1 9.4e-11 XP_016880860 (OMIM: 604881) PREDICTED: rab effecto ( 161) 560 56.7 8e-08 XP_011533671 (OMIM: 604881) PREDICTED: rab effecto ( 239) 491 51.7 4e-06 XP_016880858 (OMIM: 604881) PREDICTED: rab effecto ( 239) 491 51.7 4e-06 XP_016880859 (OMIM: 604881) PREDICTED: rab effecto ( 233) 487 51.4 4.8e-06 NP_001177342 (OMIM: 604881) rab effector Noc2 isof ( 286) 466 49.8 1.7e-05 NP_001177341 (OMIM: 604881) rab effector Noc2 isof ( 286) 466 49.8 1.7e-05 XP_011533670 (OMIM: 604881) PREDICTED: rab effecto ( 286) 466 49.8 1.7e-05 XP_016877187 (OMIM: 610950) PREDICTED: synaptotagm ( 339) 381 43.5 0.0016 XP_011535531 (OMIM: 610950) PREDICTED: synaptotagm ( 424) 381 43.6 0.0019 XP_016877185 (OMIM: 610950) PREDICTED: synaptotagm ( 462) 381 43.6 0.002 XP_011535530 (OMIM: 610950) PREDICTED: synaptotagm ( 464) 381 43.6 0.002 XP_011535529 (OMIM: 610950) PREDICTED: synaptotagm ( 505) 381 43.6 0.0022 XP_011535526 (OMIM: 610950) PREDICTED: synaptotagm ( 533) 381 43.7 0.0023 XP_011535527 (OMIM: 610950) PREDICTED: synaptotagm ( 533) 381 43.7 0.0023 XP_011535525 (OMIM: 610950) PREDICTED: synaptotagm ( 535) 381 43.7 0.0023 XP_011543638 (OMIM: 604146) PREDICTED: synaptotagm ( 651) 383 43.9 0.0024 XP_016877184 (OMIM: 610950) PREDICTED: synaptotagm ( 645) 381 43.7 0.0026 XP_006720335 (OMIM: 610950) PREDICTED: synaptotagm ( 645) 381 43.7 0.0026 XP_016877182 (OMIM: 610950) PREDICTED: synaptotagm ( 645) 381 43.7 0.0026 NP_114120 (OMIM: 610950) synaptotagmin-16 [Homo sa ( 645) 381 43.7 0.0026 XP_011535521 (OMIM: 610950) PREDICTED: synaptotagm ( 645) 381 43.7 0.0026 XP_016877183 (OMIM: 610950) PREDICTED: synaptotagm ( 645) 381 43.7 0.0026 NP_001257734 (OMIM: 607718) synaptotagmin-6 [Homo ( 425) 367 42.5 0.004 NP_995320 (OMIM: 607718) synaptotagmin-6 [Homo sap ( 425) 367 42.5 0.004 XP_016855860 (OMIM: 607718) PREDICTED: synaptotagm ( 443) 367 42.5 0.0041 NP_001238994 (OMIM: 604146) synaptotagmin-7 isofor ( 478) 367 42.6 0.0043 XP_011543642 (OMIM: 604146) PREDICTED: synaptotagm ( 484) 367 42.6 0.0044 >>XP_011536350 (OMIM: 612159) PREDICTED: rabphilin-3A is (694 aa) initn: 4813 init1: 4813 opt: 4813 Z-score: 1984.6 bits: 377.7 E(85289): 8.4e-104 Smith-Waterman score: 4813; 100.0% identity (100.0% similar) in 694 aa overlap (1-694:1-694) 10 20 30 40 50 60 pF1KA0 MTDTVFSNSSNRWMYPSDRPLQSNDKEQLQAGWSVHPGGQPDRQRKQEELTDEEKEIINR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MTDTVFSNSSNRWMYPSDRPLQSNDKEQLQAGWSVHPGGQPDRQRKQEELTDEEKEIINR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 VIARAEKMEEMEQERIGRLVDRLENMRKNVAGDGVNRCILCGEQLGMLGSACVVCEDCKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VIARAEKMEEMEQERIGRLVDRLENMRKNVAGDGVNRCILCGEQLGMLGSACVVCEDCKK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 NVCTKCGVETNNRLHSVWLCKICIEQREVWKRSGAWFFKGFPKQVLPQPMPIKKTKPQQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NVCTKCGVETNNRLHSVWLCKICIEQREVWKRSGAWFFKGFPKQVLPQPMPIKKTKPQQP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 VSEPAAPEQPAPEPKHPARAPARGDSEDRRGPGQKTGPDPASAPGRGNYGPPVRRASEAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSEPAAPEQPAPEPKHPARAPARGDSEDRRGPGQKTGPDPASAPGRGNYGPPVRRASEAR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 MSSSSRDSESWDHSGGAGDSSRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSSSSRDSESWDHSGGAGDSSRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 RPGPGPAGRFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAVGAREDRMSHPSGPYSQAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RPGPGPAGRFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAVGAREDRMSHPSGPYSQAS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 AAAPQPAAARQPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AAAPQPAAARQPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 PMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 SVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEE 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 QVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 KAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISA 610 620 630 640 650 660 670 680 690 pF1KA0 KGERLKHWYECLKNKDKKIERWHQLQNENHVSSD :::::::::::::::::::::::::::::::::: XP_011 KGERLKHWYECLKNKDKKIERWHQLQNENHVSSD 670 680 690 >>NP_001137326 (OMIM: 612159) rabphilin-3A isoform 1 [Ho (694 aa) initn: 4813 init1: 4813 opt: 4813 Z-score: 1984.6 bits: 377.7 E(85289): 8.4e-104 Smith-Waterman score: 4813; 100.0% identity (100.0% similar) in 694 aa overlap (1-694:1-694) 10 20 30 40 50 60 pF1KA0 MTDTVFSNSSNRWMYPSDRPLQSNDKEQLQAGWSVHPGGQPDRQRKQEELTDEEKEIINR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MTDTVFSNSSNRWMYPSDRPLQSNDKEQLQAGWSVHPGGQPDRQRKQEELTDEEKEIINR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA0 VIARAEKMEEMEQERIGRLVDRLENMRKNVAGDGVNRCILCGEQLGMLGSACVVCEDCKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VIARAEKMEEMEQERIGRLVDRLENMRKNVAGDGVNRCILCGEQLGMLGSACVVCEDCKK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA0 NVCTKCGVETNNRLHSVWLCKICIEQREVWKRSGAWFFKGFPKQVLPQPMPIKKTKPQQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NVCTKCGVETNNRLHSVWLCKICIEQREVWKRSGAWFFKGFPKQVLPQPMPIKKTKPQQP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA0 VSEPAAPEQPAPEPKHPARAPARGDSEDRRGPGQKTGPDPASAPGRGNYGPPVRRASEAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VSEPAAPEQPAPEPKHPARAPARGDSEDRRGPGQKTGPDPASAPGRGNYGPPVRRASEAR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA0 MSSSSRDSESWDHSGGAGDSSRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSSSSRDSESWDHSGGAGDSSRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA0 RPGPGPAGRFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAVGAREDRMSHPSGPYSQAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RPGPGPAGRFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAVGAREDRMSHPSGPYSQAS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA0 AAAPQPAAARQPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AAAPQPAAARQPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA0 PMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA0 SVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEE 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA0 QVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA0 KAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISA 610 620 630 640 650 660 670 680 690 pF1KA0 KGERLKHWYECLKNKDKKIERWHQLQNENHVSSD :::::::::::::::::::::::::::::::::: NP_001 KGERLKHWYECLKNKDKKIERWHQLQNENHVSSD 670 680 690 >>NP_055769 (OMIM: 612159) rabphilin-3A isoform 2 [Homo (690 aa) initn: 4621 init1: 4621 opt: 4763 Z-score: 1964.2 bits: 373.9 E(85289): 1.1e-102 Smith-Waterman score: 4763; 99.3% identity (99.4% similar) in 694 aa overlap (1-694:1-690) 10 20 30 40 50 60 pF1KA0 MTDTVFSNSSNRWMYPSDRPLQSNDKEQLQAGWSVHPGGQPDRQRKQEELTDEEKEIINR ::::::::::::::::::::::: .:::::::::::::::::::::::::::::::: NP_055 MTDTVFSNSSNRWMYPSDRPLQS----KLQAGWSVHPGGQPDRQRKQEELTDEEKEIINR 10 20 30 40 50 70 80 90 100 110 120 pF1KA0 VIARAEKMEEMEQERIGRLVDRLENMRKNVAGDGVNRCILCGEQLGMLGSACVVCEDCKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VIARAEKMEEMEQERIGRLVDRLENMRKNVAGDGVNRCILCGEQLGMLGSACVVCEDCKK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KA0 NVCTKCGVETNNRLHSVWLCKICIEQREVWKRSGAWFFKGFPKQVLPQPMPIKKTKPQQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 NVCTKCGVETNNRLHSVWLCKICIEQREVWKRSGAWFFKGFPKQVLPQPMPIKKTKPQQP 120 130 140 150 160 170 190 200 210 220 230 240 pF1KA0 VSEPAAPEQPAPEPKHPARAPARGDSEDRRGPGQKTGPDPASAPGRGNYGPPVRRASEAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VSEPAAPEQPAPEPKHPARAPARGDSEDRRGPGQKTGPDPASAPGRGNYGPPVRRASEAR 180 190 200 210 220 230 250 260 270 280 290 300 pF1KA0 MSSSSRDSESWDHSGGAGDSSRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MSSSSRDSESWDHSGGAGDSSRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGS 240 250 260 270 280 290 310 320 330 340 350 360 pF1KA0 RPGPGPAGRFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAVGAREDRMSHPSGPYSQAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 RPGPGPAGRFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAVGAREDRMSHPSGPYSQAS 300 310 320 330 340 350 370 380 390 400 410 420 pF1KA0 AAAPQPAAARQPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 AAAPQPAAARQPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLK 360 370 380 390 400 410 430 440 450 460 470 480 pF1KA0 PMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRI 420 430 440 450 460 470 490 500 510 520 530 540 pF1KA0 SVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEE 480 490 500 510 520 530 550 560 570 580 590 600 pF1KA0 QVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 QVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGK 540 550 560 570 580 590 610 620 630 640 650 660 pF1KA0 KAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISA 600 610 620 630 640 650 670 680 690 pF1KA0 KGERLKHWYECLKNKDKKIERWHQLQNENHVSSD :::::::::::::::::::::::::::::::::: NP_055 KGERLKHWYECLKNKDKKIERWHQLQNENHVSSD 660 670 680 690 >>XP_016874523 (OMIM: 612159) PREDICTED: rabphilin-3A is (346 aa) initn: 2334 init1: 2334 opt: 2334 Z-score: 979.3 bits: 190.7 E(85289): 8.3e-48 Smith-Waterman score: 2334; 100.0% identity (100.0% similar) in 346 aa overlap (349-694:1-346) 320 330 340 350 360 370 pF1KA0 PSDPGTTAPPREERTGGVGGYPAVGAREDRMSHPSGPYSQASAAAPQPAAARQPPPPEEE :::::::::::::::::::::::::::::: XP_016 MSHPSGPYSQASAAAPQPAAARQPPPPEEE 10 20 30 380 390 400 410 420 430 pF1KA0 EEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLP 40 50 60 70 80 90 440 450 460 470 480 490 pF1KA0 GASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETR 100 110 120 130 140 150 500 510 520 530 540 550 pF1KA0 FSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERGKILVSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERGKILVSL 160 170 180 190 200 210 560 570 580 590 600 610 pF1KA0 MYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFN 220 230 240 250 260 270 620 630 640 650 660 670 pF1KA0 EEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKK 280 290 300 310 320 330 680 690 pF1KA0 IERWHQLQNENHVSSD :::::::::::::::: XP_016 IERWHQLQNENHVSSD 340 >>XP_016879265 (OMIM: 604567) PREDICTED: double C2-like (400 aa) initn: 1398 init1: 708 opt: 1402 Z-score: 598.9 bits: 120.5 E(85289): 1.3e-26 Smith-Waterman score: 1407; 56.6% identity (75.6% similar) in 389 aa overlap (304-688:23-389) 280 290 300 310 320 330 pF1KA0 QASRPAPGSVQSPAPPQPGQPGTPGGSRPGPGPAGRFPDQKPEVAPSDPGTTAPPREERT ::: : : . : :: : : XP_016 MRGRRGDRMTINIQEHMAINVCPGPI-RPIRQISDYFPRGPG---P---EGG 10 20 30 40 340 350 360 370 380 390 pF1KA0 GGVGGYPAVGAREDRMSHPSGPYSQASAAAPQPAAARQPPPPEEEEEEANSYDSDEATTL :: :: .: . : ::: ::. : ..:::::.::.: XP_016 GGGGG--------------EAPAHLVPLALAPPAALLGATTPEDGAE-VDSYDSDDATAL 50 60 70 80 90 400 410 420 430 440 450 pF1KA0 GALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRN :.:::.::::. . .:.:.:..:::::::: :::::::::::::::: :.:::.::: :: XP_016 GTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGLADPYVKLHLLPGACKANKLKTKTQRN 100 110 120 130 140 150 460 470 480 490 500 510 pF1KA0 TRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFN : ::.::: :.: ::::.:. .:.:::.::::::..::::::: : :..:::.:.:.:: XP_016 TLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKLSHNEFIGEIRVPLRRLKPSQKKHFN 160 170 180 190 200 210 520 530 540 550 560 pF1KA0 ICLERVIPMKRAGTTGSA-RGMALY--EEEQVER-VGDIEERGKILVSLMYSTQQGGLIV ::::: .:. .. ..: ::.. : : ::.:. : .::::.::.:: ::... ::.: XP_016 ICLERQVPLASPSSMSAALRGISCYLKELEQAEQGQGLLEERGRILLSLSYSSRRRGLLV 220 230 240 250 260 270 570 580 590 600 610 620 pF1KA0 GIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSD ::.::.::::::.::::::.:: .:.::. ::.:::: .:::::::::::::::.:. : XP_016 GILRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKKTLNPEFNEEFFYEIELST 280 290 300 310 320 330 630 640 650 660 670 680 pF1KA0 LAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQLQNEN :: :.:...:::::::::::.::: .:: .:.:: ::: .::.. : .:::: : .: XP_016 LATKTLEVTVWDYDIGKSNDFIGGVSLGPGARGEARKHWSDCLQQPDAALERWHTLTSEL 340 350 360 370 380 390 690 pF1KA0 HVSSD XP_016 PPAAGALSSA 400 >>XP_016879266 (OMIM: 604567) PREDICTED: double C2-like (400 aa) initn: 1398 init1: 708 opt: 1402 Z-score: 598.9 bits: 120.5 E(85289): 1.3e-26 Smith-Waterman score: 1407; 56.6% identity (75.6% similar) in 389 aa overlap (304-688:23-389) 280 290 300 310 320 330 pF1KA0 QASRPAPGSVQSPAPPQPGQPGTPGGSRPGPGPAGRFPDQKPEVAPSDPGTTAPPREERT ::: : : . : :: : : XP_016 MRGRRGDRMTINIQEHMAINVCPGPI-RPIRQISDYFPRGPG---P---EGG 10 20 30 40 340 350 360 370 380 390 pF1KA0 GGVGGYPAVGAREDRMSHPSGPYSQASAAAPQPAAARQPPPPEEEEEEANSYDSDEATTL :: :: .: . : ::: ::. : ..:::::.::.: XP_016 GGGGG--------------EAPAHLVPLALAPPAALLGATTPEDGAE-VDSYDSDDATAL 50 60 70 80 90 400 410 420 430 440 450 pF1KA0 GALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRN :.:::.::::. . .:.:.:..:::::::: :::::::::::::::: :.:::.::: :: XP_016 GTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGLADPYVKLHLLPGACKANKLKTKTQRN 100 110 120 130 140 150 460 470 480 490 500 510 pF1KA0 TRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFN : ::.::: :.: ::::.:. .:.:::.::::::..::::::: : :..:::.:.:.:: XP_016 TLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKLSHNEFIGEIRVPLRRLKPSQKKHFN 160 170 180 190 200 210 520 530 540 550 560 pF1KA0 ICLERVIPMKRAGTTGSA-RGMALY--EEEQVER-VGDIEERGKILVSLMYSTQQGGLIV ::::: .:. .. ..: ::.. : : ::.:. : .::::.::.:: ::... ::.: XP_016 ICLERQVPLASPSSMSAALRGISCYLKELEQAEQGQGLLEERGRILLSLSYSSRRRGLLV 220 230 240 250 260 270 570 580 590 600 610 620 pF1KA0 GIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSD ::.::.::::::.::::::.:: .:.::. ::.:::: .:::::::::::::::.:. : XP_016 GILRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKKTLNPEFNEEFFYEIELST 280 290 300 310 320 330 630 640 650 660 670 680 pF1KA0 LAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQLQNEN :: :.:...:::::::::::.::: .:: .:.:: ::: .::.. : .:::: : .: XP_016 LATKTLEVTVWDYDIGKSNDFIGGVSLGPGARGEARKHWSDCLQQPDAALERWHTLTSEL 340 350 360 370 380 390 690 pF1KA0 HVSSD XP_016 PPAAGALSSA 400 >>NP_001268997 (OMIM: 604567) double C2-like domain-cont (400 aa) initn: 1398 init1: 708 opt: 1402 Z-score: 598.9 bits: 120.5 E(85289): 1.3e-26 Smith-Waterman score: 1407; 56.6% identity (75.6% similar) in 389 aa overlap (304-688:23-389) 280 290 300 310 320 330 pF1KA0 QASRPAPGSVQSPAPPQPGQPGTPGGSRPGPGPAGRFPDQKPEVAPSDPGTTAPPREERT ::: : : . : :: : : NP_001 MRGRRGDRMTINIQEHMAINVCPGPI-RPIRQISDYFPRGPG---P---EGG 10 20 30 40 340 350 360 370 380 390 pF1KA0 GGVGGYPAVGAREDRMSHPSGPYSQASAAAPQPAAARQPPPPEEEEEEANSYDSDEATTL :: :: .: . : ::: ::. : ..:::::.::.: NP_001 GGGGG--------------EAPAHLVPLALAPPAALLGATTPEDGAE-VDSYDSDDATAL 50 60 70 80 90 400 410 420 430 440 450 pF1KA0 GALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRN :.:::.::::. . .:.:.:..:::::::: :::::::::::::::: :.:::.::: :: NP_001 GTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGLADPYVKLHLLPGACKANKLKTKTQRN 100 110 120 130 140 150 460 470 480 490 500 510 pF1KA0 TRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFN : ::.::: :.: ::::.:. .:.:::.::::::..::::::: : :..:::.:.:.:: NP_001 TLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKLSHNEFIGEIRVPLRRLKPSQKKHFN 160 170 180 190 200 210 520 530 540 550 560 pF1KA0 ICLERVIPMKRAGTTGSA-RGMALY--EEEQVER-VGDIEERGKILVSLMYSTQQGGLIV ::::: .:. .. ..: ::.. : : ::.:. : .::::.::.:: ::... ::.: NP_001 ICLERQVPLASPSSMSAALRGISCYLKELEQAEQGQGLLEERGRILLSLSYSSRRRGLLV 220 230 240 250 260 270 570 580 590 600 610 620 pF1KA0 GIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSD ::.::.::::::.::::::.:: .:.::. ::.:::: .:::::::::::::::.:. : NP_001 GILRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKKTLNPEFNEEFFYEIELST 280 290 300 310 320 330 630 640 650 660 670 680 pF1KA0 LAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQLQNEN :: :.:...:::::::::::.::: .:: .:.:: ::: .::.. : .:::: : .: NP_001 LATKTLEVTVWDYDIGKSNDFIGGVSLGPGARGEARKHWSDCLQQPDAALERWHTLTSEL 340 350 360 370 380 390 690 pF1KA0 HVSSD NP_001 PPAAGALSSA 400 >>NP_003577 (OMIM: 604567) double C2-like domain-contain (400 aa) initn: 1398 init1: 708 opt: 1402 Z-score: 598.9 bits: 120.5 E(85289): 1.3e-26 Smith-Waterman score: 1407; 56.6% identity (75.6% similar) in 389 aa overlap (304-688:23-389) 280 290 300 310 320 330 pF1KA0 QASRPAPGSVQSPAPPQPGQPGTPGGSRPGPGPAGRFPDQKPEVAPSDPGTTAPPREERT ::: : : . : :: : : NP_003 MRGRRGDRMTINIQEHMAINVCPGPI-RPIRQISDYFPRGPG---P---EGG 10 20 30 40 340 350 360 370 380 390 pF1KA0 GGVGGYPAVGAREDRMSHPSGPYSQASAAAPQPAAARQPPPPEEEEEEANSYDSDEATTL :: :: .: . : ::: ::. : ..:::::.::.: NP_003 GGGGG--------------EAPAHLVPLALAPPAALLGATTPEDGAE-VDSYDSDDATAL 50 60 70 80 90 400 410 420 430 440 450 pF1KA0 GALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRN :.:::.::::. . .:.:.:..:::::::: :::::::::::::::: :.:::.::: :: NP_003 GTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGLADPYVKLHLLPGACKANKLKTKTQRN 100 110 120 130 140 150 460 470 480 490 500 510 pF1KA0 TRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFN : ::.::: :.: ::::.:. .:.:::.::::::..::::::: : :..:::.:.:.:: NP_003 TLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKLSHNEFIGEIRVPLRRLKPSQKKHFN 160 170 180 190 200 210 520 530 540 550 560 pF1KA0 ICLERVIPMKRAGTTGSA-RGMALY--EEEQVER-VGDIEERGKILVSLMYSTQQGGLIV ::::: .:. .. ..: ::.. : : ::.:. : .::::.::.:: ::... ::.: NP_003 ICLERQVPLASPSSMSAALRGISCYLKELEQAEQGQGLLEERGRILLSLSYSSRRRGLLV 220 230 240 250 260 270 570 580 590 600 610 620 pF1KA0 GIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSD ::.::.::::::.::::::.:: .:.::. ::.:::: .:::::::::::::::.:. : NP_003 GILRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKKTLNPEFNEEFFYEIELST 280 290 300 310 320 330 630 640 650 660 670 680 pF1KA0 LAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQLQNEN :: :.:...:::::::::::.::: .:: .:.:: ::: .::.. : .:::: : .: NP_003 LATKTLEVTVWDYDIGKSNDFIGGVSLGPGARGEARKHWSDCLQQPDAALERWHTLTSEL 340 350 360 370 380 390 690 pF1KA0 HVSSD NP_003 PPAAGALSSA 400 >>NP_001268992 (OMIM: 604567) double C2-like domain-cont (400 aa) initn: 1398 init1: 708 opt: 1402 Z-score: 598.9 bits: 120.5 E(85289): 1.3e-26 Smith-Waterman score: 1407; 56.6% identity (75.6% similar) in 389 aa overlap (304-688:23-389) 280 290 300 310 320 330 pF1KA0 QASRPAPGSVQSPAPPQPGQPGTPGGSRPGPGPAGRFPDQKPEVAPSDPGTTAPPREERT ::: : : . : :: : : NP_001 MRGRRGDRMTINIQEHMAINVCPGPI-RPIRQISDYFPRGPG---P---EGG 10 20 30 40 340 350 360 370 380 390 pF1KA0 GGVGGYPAVGAREDRMSHPSGPYSQASAAAPQPAAARQPPPPEEEEEEANSYDSDEATTL :: :: .: . : ::: ::. : ..:::::.::.: NP_001 GGGGG--------------EAPAHLVPLALAPPAALLGATTPEDGAE-VDSYDSDDATAL 50 60 70 80 90 400 410 420 430 440 450 pF1KA0 GALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRN :.:::.::::. . .:.:.:..:::::::: :::::::::::::::: :.:::.::: :: NP_001 GTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGLADPYVKLHLLPGACKANKLKTKTQRN 100 110 120 130 140 150 460 470 480 490 500 510 pF1KA0 TRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFN : ::.::: :.: ::::.:. .:.:::.::::::..::::::: : :..:::.:.:.:: NP_001 TLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKLSHNEFIGEIRVPLRRLKPSQKKHFN 160 170 180 190 200 210 520 530 540 550 560 pF1KA0 ICLERVIPMKRAGTTGSA-RGMALY--EEEQVER-VGDIEERGKILVSLMYSTQQGGLIV ::::: .:. .. ..: ::.. : : ::.:. : .::::.::.:: ::... ::.: NP_001 ICLERQVPLASPSSMSAALRGISCYLKELEQAEQGQGLLEERGRILLSLSYSSRRRGLLV 220 230 240 250 260 270 570 580 590 600 610 620 pF1KA0 GIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSD ::.::.::::::.::::::.:: .:.::. ::.:::: .:::::::::::::::.:. : NP_001 GILRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKKTLNPEFNEEFFYEIELST 280 290 300 310 320 330 630 640 650 660 670 680 pF1KA0 LAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQLQNEN :: :.:...:::::::::::.::: .:: .:.:: ::: .::.. : .:::: : .: NP_001 LATKTLEVTVWDYDIGKSNDFIGGVSLGPGARGEARKHWSDCLQQPDAALERWHTLTSEL 340 350 360 370 380 390 690 pF1KA0 HVSSD NP_001 PPAAGALSSA 400 >>NP_001268991 (OMIM: 604567) double C2-like domain-cont (400 aa) initn: 1398 init1: 708 opt: 1402 Z-score: 598.9 bits: 120.5 E(85289): 1.3e-26 Smith-Waterman score: 1407; 56.6% identity (75.6% similar) in 389 aa overlap (304-688:23-389) 280 290 300 310 320 330 pF1KA0 QASRPAPGSVQSPAPPQPGQPGTPGGSRPGPGPAGRFPDQKPEVAPSDPGTTAPPREERT ::: : : . : :: : : NP_001 MRGRRGDRMTINIQEHMAINVCPGPI-RPIRQISDYFPRGPG---P---EGG 10 20 30 40 340 350 360 370 380 390 pF1KA0 GGVGGYPAVGAREDRMSHPSGPYSQASAAAPQPAAARQPPPPEEEEEEANSYDSDEATTL :: :: .: . : ::: ::. : ..:::::.::.: NP_001 GGGGG--------------EAPAHLVPLALAPPAALLGATTPEDGAE-VDSYDSDDATAL 50 60 70 80 90 400 410 420 430 440 450 pF1KA0 GALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRN :.:::.::::. . .:.:.:..:::::::: :::::::::::::::: :.:::.::: :: NP_001 GTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGLADPYVKLHLLPGACKANKLKTKTQRN 100 110 120 130 140 150 460 470 480 490 500 510 pF1KA0 TRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFN : ::.::: :.: ::::.:. .:.:::.::::::..::::::: : :..:::.:.:.:: NP_001 TLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKLSHNEFIGEIRVPLRRLKPSQKKHFN 160 170 180 190 200 210 520 530 540 550 560 pF1KA0 ICLERVIPMKRAGTTGSA-RGMALY--EEEQVER-VGDIEERGKILVSLMYSTQQGGLIV ::::: .:. .. ..: ::.. : : ::.:. : .::::.::.:: ::... ::.: NP_001 ICLERQVPLASPSSMSAALRGISCYLKELEQAEQGQGLLEERGRILLSLSYSSRRRGLLV 220 230 240 250 260 270 570 580 590 600 610 620 pF1KA0 GIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSD ::.::.::::::.::::::.:: .:.::. ::.:::: .:::::::::::::::.:. : NP_001 GILRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKKTLNPEFNEEFFYEIELST 280 290 300 310 320 330 630 640 650 660 670 680 pF1KA0 LAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQLQNEN :: :.:...:::::::::::.::: .:: .:.:: ::: .::.. : .:::: : .: NP_001 LATKTLEVTVWDYDIGKSNDFIGGVSLGPGARGEARKHWSDCLQQPDAALERWHTLTSEL 340 350 360 370 380 390 690 pF1KA0 HVSSD NP_001 PPAAGALSSA 400 694 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 20:11:59 2016 done: Wed Nov 2 20:12:00 2016 Total Scan time: 12.060 Total Display time: 0.100 Function used was FASTA [36.3.4 Apr, 2011]