FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1006, 1186 aa 1>>>pF1KA1006 1186 - 1186 aa - 1186 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.7158+/-0.000407; mu= 16.5811+/- 0.026 mean_var=120.0336+/-24.431, 0's: 0 Z-trim(114.8): 57 B-trim: 0 in 0/52 Lambda= 0.117064 statistics sampled from 24851 (24907) to 24851 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.631), E-opt: 0.2 (0.292), width: 16 Scan time: 14.120 The best scores are: opt bits E(85289) NP_055795 (OMIM: 609381) syntaxin-binding protein (1186) 7980 1359.9 0 XP_006713888 (OMIM: 609381) PREDICTED: syntaxin-bi (1186) 7980 1359.9 0 XP_016863019 (OMIM: 609381) PREDICTED: syntaxin-bi (1186) 7980 1359.9 0 XP_016863022 (OMIM: 609381) PREDICTED: syntaxin-bi ( 999) 6482 1106.9 0 XP_011511630 (OMIM: 609381) PREDICTED: syntaxin-bi ( 825) 5460 934.2 0 XP_016863023 (OMIM: 609381) PREDICTED: syntaxin-bi ( 739) 4939 846.2 0 XP_011511633 (OMIM: 609381) PREDICTED: syntaxin-bi ( 715) 4747 813.8 0 XP_016863020 (OMIM: 609381) PREDICTED: syntaxin-bi (1162) 4747 813.9 0 XP_016863021 (OMIM: 609381) PREDICTED: syntaxin-bi (1162) 4747 813.9 0 NP_001295259 (OMIM: 609381) syntaxin-binding prote (1162) 4747 813.9 0 XP_011511634 (OMIM: 609381) PREDICTED: syntaxin-bi ( 702) 4675 801.6 0 XP_011511635 (OMIM: 609381) PREDICTED: syntaxin-bi ( 654) 4417 758.0 4.4e-218 XP_016863024 (OMIM: 609381) PREDICTED: syntaxin-bi ( 654) 4417 758.0 4.4e-218 XP_016865757 (OMIM: 604586) PREDICTED: syntaxin-bi ( 746) 3435 592.2 4.1e-168 NP_640337 (OMIM: 604586) syntaxin-binding protein (1115) 3405 587.2 1.9e-166 NP_001121187 (OMIM: 604586) syntaxin-binding prote (1151) 3399 586.2 3.9e-166 XP_006715402 (OMIM: 604586) PREDICTED: syntaxin-bi (1135) 3397 585.9 4.9e-166 XP_016865756 (OMIM: 604586) PREDICTED: syntaxin-bi ( 947) 2317 403.4 3.4e-111 XP_011533755 (OMIM: 604586) PREDICTED: syntaxin-bi ( 806) 1855 325.4 9.2e-88 XP_011522158 (OMIM: 600966) PREDICTED: lethal(2) g (1035) 320 66.2 1.2e-09 XP_011522157 (OMIM: 600966) PREDICTED: lethal(2) g (1062) 320 66.2 1.3e-09 NP_004131 (OMIM: 600966) lethal(2) giant larvae pr (1064) 320 66.2 1.3e-09 XP_011522156 (OMIM: 600966) PREDICTED: lethal(2) g (1084) 320 66.2 1.3e-09 XP_011522155 (OMIM: 600966) PREDICTED: lethal(2) g (1085) 320 66.2 1.3e-09 XP_011522153 (OMIM: 600966) PREDICTED: lethal(2) g (1103) 320 66.2 1.3e-09 XP_011522154 (OMIM: 600966) PREDICTED: lethal(2) g (1103) 320 66.2 1.3e-09 XP_011522152 (OMIM: 600966) PREDICTED: lethal(2) g (1104) 320 66.2 1.3e-09 XP_011522151 (OMIM: 600966) PREDICTED: lethal(2) g (1105) 320 66.2 1.3e-09 NP_443730 (OMIM: 610778) guanine nucleotide-bindin ( 327) 178 41.9 0.0082 >>NP_055795 (OMIM: 609381) syntaxin-binding protein 5-li (1186 aa) initn: 7980 init1: 7980 opt: 7980 Z-score: 7284.8 bits: 1359.9 E(85289): 0 Smith-Waterman score: 7980; 100.0% identity (100.0% similar) in 1186 aa overlap (1-1186:1-1186) 10 20 30 40 50 60 pF1KA1 MKKFNFRKVLDGLTASSPGSGSSSGSNSGGGAGSGSVHPAGTAGVLREEIQETLTSEYFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MKKFNFRKVLDGLTASSPGSGSSSGSNSGGGAGSGSVHPAGTAGVLREEIQETLTSEYFQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 ICKTVRHGFPHQPTALAFDPVQKILAIGTRTGAIRILGRPGVDCYCQHESGAAVLQLQFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ICKTVRHGFPHQPTALAFDPVQKILAIGTRTGAIRILGRPGVDCYCQHESGAAVLQLQFL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 INEGALVSASSDDTLHLWNLRQKRPAILHSLKFNRERITYCHLPFQSKWLYVGTERGNTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 INEGALVSASSDDTLHLWNLRQKRPAILHSLKFNRERITYCHLPFQSKWLYVGTERGNTH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 IVNIESFILSGYVIMWNKAIELSTKTHPGPVVHLSDSPRDEGKLLIGYENGTVVFWDLKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 IVNIESFILSGYVIMWNKAIELSTKTHPGPVVHLSDSPRDEGKLLIGYENGTVVFWDLKS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 KRAELRVYYDEAIHSIDWHHEGKQFMCSHSDGSLTLWNLKSPSRPFQTTIPHGKSQREGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KRAELRVYYDEAIHSIDWHHEGKQFMCSHSDGSLTLWNLKSPSRPFQTTIPHGKSQREGR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 KSESCKPILKVEYKTCKNSEPFIIFSGGLSYDKACRRPSLTIMHGKAITVLEMDHPIVEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KSESCKPILKVEYKTCKNSEPFIIFSGGLSYDKACRRPSLTIMHGKAITVLEMDHPIVEF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 LTLCETPYPNEFQEPYAVVVLLEKDLIVVDLTQSNFPIFENPYPMDIHESPVTCTAYFAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LTLCETPYPNEFQEPYAVVVLLEKDLIVVDLTQSNFPIFENPYPMDIHESPVTCTAYFAD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 CPPDLILVLYSIGVKHKKQGYSNKEWPISGGAWNLGAQTYPEIIITGHADGSIKFWDASA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 CPPDLILVLYSIGVKHKKQGYSNKEWPISGGAWNLGAQTYPEIIITGHADGSIKFWDASA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 ITLQMLYKLKTSKVFEKQKVGEGKQTCEIVEEDPFAIQMIYWCPESRIFCVSGVSAYVII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ITLQMLYKLKTSKVFEKQKVGEGKQTCEIVEEDPFAIQMIYWCPESRIFCVSGVSAYVII 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 YKFSRHEITTEIVSLEVRLQYDVEDIITPEPETSPPFPDLSAQLPSSRSLSGSTNTVASE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 YKFSRHEITTEIVSLEVRLQYDVEDIITPEPETSPPFPDLSAQLPSSRSLSGSTNTVASE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 GVTKDSIPCLNVKTRPVRMPPGYQAELVIQLVWVDGEPPQQITSLAVSSAYGIVAFGNCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GVTKDSIPCLNVKTRPVRMPPGYQAELVIQLVWVDGEPPQQITSLAVSSAYGIVAFGNCN 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 GLAVVDFIQKTVLLSMGTIDLYRSSDLYQRQPRSPRKNKQFIADNFCMRGLSNFYPDLTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GLAVVDFIQKTVLLSMGTIDLYRSSDLYQRQPRSPRKNKQFIADNFCMRGLSNFYPDLTK 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 RIRTSYQSLTELNDSPVPLELERCKSPTSDHVNGHCTSPTSQSCSSGKRLSSADVSKVNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 RIRTSYQSLTELNDSPVPLELERCKSPTSDHVNGHCTSPTSQSCSSGKRLSSADVSKVNR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 WGPGRPPFRKAQSAACMEISLPVTTEENRENSYNRSRSSSISSIDKDSKEAITALYFMDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 WGPGRPPFRKAQSAACMEISLPVTTEENRENSYNRSRSSSISSIDKDSKEAITALYFMDS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 FARKNDSTISPCLFVGTSLGMVLIISLNLPLADEQRFTEPVMVLPSGTFLSLKGAVLTFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 FARKNDSTISPCLFVGTSLGMVLIISLNLPLADEQRFTEPVMVLPSGTFLSLKGAVLTFS 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 CMDRMGGLMQPPYEVWRDPNNIDENEKSWRRKVVMNSSSASQEIGDHQYTIICSEKQAKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 CMDRMGGLMQPPYEVWRDPNNIDENEKSWRRKVVMNSSSASQEIGDHQYTIICSEKQAKV 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 FSLPSQTCLYVHNITETSFILQANVVVMCSSACLACFCANGHIMIMSLPSLRPMLDVNYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 FSLPSQTCLYVHNITETSFILQANVVVMCSSACLACFCANGHIMIMSLPSLRPMLDVNYL 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA1 PLTDMRIARTFCFTNEGQALYLVSPTEIQRLTYSQEMCDNLQDMLGDLFTPIETPEAQNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PLTDMRIARTFCFTNEGQALYLVSPTEIQRLTYSQEMCDNLQDMLGDLFTPIETPEAQNR 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA1 GFLKGLFGGSGQTFDREELFGEASAGKASRSLAQHIPGPGSIEGMKGAAGGVMGELTRAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GFLKGLFGGSGQTFDREELFGEASAGKASRSLAQHIPGPGSIEGMKGAAGGVMGELTRAR 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 pF1KA1 IALDERGQRLGELEEKTAGMMTSAEAFSKHAHELMLKYKDKKWYQF :::::::::::::::::::::::::::::::::::::::::::::: NP_055 IALDERGQRLGELEEKTAGMMTSAEAFSKHAHELMLKYKDKKWYQF 1150 1160 1170 1180 >>XP_006713888 (OMIM: 609381) PREDICTED: syntaxin-bindin (1186 aa) initn: 7980 init1: 7980 opt: 7980 Z-score: 7284.8 bits: 1359.9 E(85289): 0 Smith-Waterman score: 7980; 100.0% identity (100.0% similar) in 1186 aa overlap (1-1186:1-1186) 10 20 30 40 50 60 pF1KA1 MKKFNFRKVLDGLTASSPGSGSSSGSNSGGGAGSGSVHPAGTAGVLREEIQETLTSEYFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MKKFNFRKVLDGLTASSPGSGSSSGSNSGGGAGSGSVHPAGTAGVLREEIQETLTSEYFQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 ICKTVRHGFPHQPTALAFDPVQKILAIGTRTGAIRILGRPGVDCYCQHESGAAVLQLQFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ICKTVRHGFPHQPTALAFDPVQKILAIGTRTGAIRILGRPGVDCYCQHESGAAVLQLQFL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 INEGALVSASSDDTLHLWNLRQKRPAILHSLKFNRERITYCHLPFQSKWLYVGTERGNTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 INEGALVSASSDDTLHLWNLRQKRPAILHSLKFNRERITYCHLPFQSKWLYVGTERGNTH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 IVNIESFILSGYVIMWNKAIELSTKTHPGPVVHLSDSPRDEGKLLIGYENGTVVFWDLKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IVNIESFILSGYVIMWNKAIELSTKTHPGPVVHLSDSPRDEGKLLIGYENGTVVFWDLKS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 KRAELRVYYDEAIHSIDWHHEGKQFMCSHSDGSLTLWNLKSPSRPFQTTIPHGKSQREGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KRAELRVYYDEAIHSIDWHHEGKQFMCSHSDGSLTLWNLKSPSRPFQTTIPHGKSQREGR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 KSESCKPILKVEYKTCKNSEPFIIFSGGLSYDKACRRPSLTIMHGKAITVLEMDHPIVEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KSESCKPILKVEYKTCKNSEPFIIFSGGLSYDKACRRPSLTIMHGKAITVLEMDHPIVEF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 LTLCETPYPNEFQEPYAVVVLLEKDLIVVDLTQSNFPIFENPYPMDIHESPVTCTAYFAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LTLCETPYPNEFQEPYAVVVLLEKDLIVVDLTQSNFPIFENPYPMDIHESPVTCTAYFAD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 CPPDLILVLYSIGVKHKKQGYSNKEWPISGGAWNLGAQTYPEIIITGHADGSIKFWDASA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CPPDLILVLYSIGVKHKKQGYSNKEWPISGGAWNLGAQTYPEIIITGHADGSIKFWDASA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 ITLQMLYKLKTSKVFEKQKVGEGKQTCEIVEEDPFAIQMIYWCPESRIFCVSGVSAYVII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ITLQMLYKLKTSKVFEKQKVGEGKQTCEIVEEDPFAIQMIYWCPESRIFCVSGVSAYVII 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 YKFSRHEITTEIVSLEVRLQYDVEDIITPEPETSPPFPDLSAQLPSSRSLSGSTNTVASE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YKFSRHEITTEIVSLEVRLQYDVEDIITPEPETSPPFPDLSAQLPSSRSLSGSTNTVASE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 GVTKDSIPCLNVKTRPVRMPPGYQAELVIQLVWVDGEPPQQITSLAVSSAYGIVAFGNCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GVTKDSIPCLNVKTRPVRMPPGYQAELVIQLVWVDGEPPQQITSLAVSSAYGIVAFGNCN 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 GLAVVDFIQKTVLLSMGTIDLYRSSDLYQRQPRSPRKNKQFIADNFCMRGLSNFYPDLTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GLAVVDFIQKTVLLSMGTIDLYRSSDLYQRQPRSPRKNKQFIADNFCMRGLSNFYPDLTK 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 RIRTSYQSLTELNDSPVPLELERCKSPTSDHVNGHCTSPTSQSCSSGKRLSSADVSKVNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RIRTSYQSLTELNDSPVPLELERCKSPTSDHVNGHCTSPTSQSCSSGKRLSSADVSKVNR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 WGPGRPPFRKAQSAACMEISLPVTTEENRENSYNRSRSSSISSIDKDSKEAITALYFMDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 WGPGRPPFRKAQSAACMEISLPVTTEENRENSYNRSRSSSISSIDKDSKEAITALYFMDS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 FARKNDSTISPCLFVGTSLGMVLIISLNLPLADEQRFTEPVMVLPSGTFLSLKGAVLTFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FARKNDSTISPCLFVGTSLGMVLIISLNLPLADEQRFTEPVMVLPSGTFLSLKGAVLTFS 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 CMDRMGGLMQPPYEVWRDPNNIDENEKSWRRKVVMNSSSASQEIGDHQYTIICSEKQAKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CMDRMGGLMQPPYEVWRDPNNIDENEKSWRRKVVMNSSSASQEIGDHQYTIICSEKQAKV 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 FSLPSQTCLYVHNITETSFILQANVVVMCSSACLACFCANGHIMIMSLPSLRPMLDVNYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FSLPSQTCLYVHNITETSFILQANVVVMCSSACLACFCANGHIMIMSLPSLRPMLDVNYL 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA1 PLTDMRIARTFCFTNEGQALYLVSPTEIQRLTYSQEMCDNLQDMLGDLFTPIETPEAQNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PLTDMRIARTFCFTNEGQALYLVSPTEIQRLTYSQEMCDNLQDMLGDLFTPIETPEAQNR 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA1 GFLKGLFGGSGQTFDREELFGEASAGKASRSLAQHIPGPGSIEGMKGAAGGVMGELTRAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GFLKGLFGGSGQTFDREELFGEASAGKASRSLAQHIPGPGSIEGMKGAAGGVMGELTRAR 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 pF1KA1 IALDERGQRLGELEEKTAGMMTSAEAFSKHAHELMLKYKDKKWYQF :::::::::::::::::::::::::::::::::::::::::::::: XP_006 IALDERGQRLGELEEKTAGMMTSAEAFSKHAHELMLKYKDKKWYQF 1150 1160 1170 1180 >>XP_016863019 (OMIM: 609381) PREDICTED: syntaxin-bindin (1186 aa) initn: 7980 init1: 7980 opt: 7980 Z-score: 7284.8 bits: 1359.9 E(85289): 0 Smith-Waterman score: 7980; 100.0% identity (100.0% similar) in 1186 aa overlap (1-1186:1-1186) 10 20 30 40 50 60 pF1KA1 MKKFNFRKVLDGLTASSPGSGSSSGSNSGGGAGSGSVHPAGTAGVLREEIQETLTSEYFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MKKFNFRKVLDGLTASSPGSGSSSGSNSGGGAGSGSVHPAGTAGVLREEIQETLTSEYFQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 ICKTVRHGFPHQPTALAFDPVQKILAIGTRTGAIRILGRPGVDCYCQHESGAAVLQLQFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ICKTVRHGFPHQPTALAFDPVQKILAIGTRTGAIRILGRPGVDCYCQHESGAAVLQLQFL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 INEGALVSASSDDTLHLWNLRQKRPAILHSLKFNRERITYCHLPFQSKWLYVGTERGNTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 INEGALVSASSDDTLHLWNLRQKRPAILHSLKFNRERITYCHLPFQSKWLYVGTERGNTH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 IVNIESFILSGYVIMWNKAIELSTKTHPGPVVHLSDSPRDEGKLLIGYENGTVVFWDLKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IVNIESFILSGYVIMWNKAIELSTKTHPGPVVHLSDSPRDEGKLLIGYENGTVVFWDLKS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 KRAELRVYYDEAIHSIDWHHEGKQFMCSHSDGSLTLWNLKSPSRPFQTTIPHGKSQREGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KRAELRVYYDEAIHSIDWHHEGKQFMCSHSDGSLTLWNLKSPSRPFQTTIPHGKSQREGR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 KSESCKPILKVEYKTCKNSEPFIIFSGGLSYDKACRRPSLTIMHGKAITVLEMDHPIVEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSESCKPILKVEYKTCKNSEPFIIFSGGLSYDKACRRPSLTIMHGKAITVLEMDHPIVEF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 LTLCETPYPNEFQEPYAVVVLLEKDLIVVDLTQSNFPIFENPYPMDIHESPVTCTAYFAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTLCETPYPNEFQEPYAVVVLLEKDLIVVDLTQSNFPIFENPYPMDIHESPVTCTAYFAD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 CPPDLILVLYSIGVKHKKQGYSNKEWPISGGAWNLGAQTYPEIIITGHADGSIKFWDASA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CPPDLILVLYSIGVKHKKQGYSNKEWPISGGAWNLGAQTYPEIIITGHADGSIKFWDASA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 ITLQMLYKLKTSKVFEKQKVGEGKQTCEIVEEDPFAIQMIYWCPESRIFCVSGVSAYVII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ITLQMLYKLKTSKVFEKQKVGEGKQTCEIVEEDPFAIQMIYWCPESRIFCVSGVSAYVII 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 YKFSRHEITTEIVSLEVRLQYDVEDIITPEPETSPPFPDLSAQLPSSRSLSGSTNTVASE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YKFSRHEITTEIVSLEVRLQYDVEDIITPEPETSPPFPDLSAQLPSSRSLSGSTNTVASE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 GVTKDSIPCLNVKTRPVRMPPGYQAELVIQLVWVDGEPPQQITSLAVSSAYGIVAFGNCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GVTKDSIPCLNVKTRPVRMPPGYQAELVIQLVWVDGEPPQQITSLAVSSAYGIVAFGNCN 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 GLAVVDFIQKTVLLSMGTIDLYRSSDLYQRQPRSPRKNKQFIADNFCMRGLSNFYPDLTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLAVVDFIQKTVLLSMGTIDLYRSSDLYQRQPRSPRKNKQFIADNFCMRGLSNFYPDLTK 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 RIRTSYQSLTELNDSPVPLELERCKSPTSDHVNGHCTSPTSQSCSSGKRLSSADVSKVNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RIRTSYQSLTELNDSPVPLELERCKSPTSDHVNGHCTSPTSQSCSSGKRLSSADVSKVNR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 WGPGRPPFRKAQSAACMEISLPVTTEENRENSYNRSRSSSISSIDKDSKEAITALYFMDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WGPGRPPFRKAQSAACMEISLPVTTEENRENSYNRSRSSSISSIDKDSKEAITALYFMDS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 FARKNDSTISPCLFVGTSLGMVLIISLNLPLADEQRFTEPVMVLPSGTFLSLKGAVLTFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FARKNDSTISPCLFVGTSLGMVLIISLNLPLADEQRFTEPVMVLPSGTFLSLKGAVLTFS 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 CMDRMGGLMQPPYEVWRDPNNIDENEKSWRRKVVMNSSSASQEIGDHQYTIICSEKQAKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CMDRMGGLMQPPYEVWRDPNNIDENEKSWRRKVVMNSSSASQEIGDHQYTIICSEKQAKV 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 FSLPSQTCLYVHNITETSFILQANVVVMCSSACLACFCANGHIMIMSLPSLRPMLDVNYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FSLPSQTCLYVHNITETSFILQANVVVMCSSACLACFCANGHIMIMSLPSLRPMLDVNYL 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA1 PLTDMRIARTFCFTNEGQALYLVSPTEIQRLTYSQEMCDNLQDMLGDLFTPIETPEAQNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLTDMRIARTFCFTNEGQALYLVSPTEIQRLTYSQEMCDNLQDMLGDLFTPIETPEAQNR 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA1 GFLKGLFGGSGQTFDREELFGEASAGKASRSLAQHIPGPGSIEGMKGAAGGVMGELTRAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GFLKGLFGGSGQTFDREELFGEASAGKASRSLAQHIPGPGSIEGMKGAAGGVMGELTRAR 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 pF1KA1 IALDERGQRLGELEEKTAGMMTSAEAFSKHAHELMLKYKDKKWYQF :::::::::::::::::::::::::::::::::::::::::::::: XP_016 IALDERGQRLGELEEKTAGMMTSAEAFSKHAHELMLKYKDKKWYQF 1150 1160 1170 1180 >>XP_016863022 (OMIM: 609381) PREDICTED: syntaxin-bindin (999 aa) initn: 6482 init1: 6482 opt: 6482 Z-score: 5918.5 bits: 1106.9 E(85289): 0 Smith-Waterman score: 6482; 100.0% identity (100.0% similar) in 963 aa overlap (224-1186:37-999) 200 210 220 230 240 250 pF1KA1 IMWNKAIELSTKTHPGPVVHLSDSPRDEGKLLIGYENGTVVFWDLKSKRAELRVYYDEAI :::::::::::::::::::::::::::::: XP_016 DSDWHTISSPGSPACQLTLQILGLVSLHNHLLIGYENGTVVFWDLKSKRAELRVYYDEAI 10 20 30 40 50 60 260 270 280 290 300 310 pF1KA1 HSIDWHHEGKQFMCSHSDGSLTLWNLKSPSRPFQTTIPHGKSQREGRKSESCKPILKVEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HSIDWHHEGKQFMCSHSDGSLTLWNLKSPSRPFQTTIPHGKSQREGRKSESCKPILKVEY 70 80 90 100 110 120 320 330 340 350 360 370 pF1KA1 KTCKNSEPFIIFSGGLSYDKACRRPSLTIMHGKAITVLEMDHPIVEFLTLCETPYPNEFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KTCKNSEPFIIFSGGLSYDKACRRPSLTIMHGKAITVLEMDHPIVEFLTLCETPYPNEFQ 130 140 150 160 170 180 380 390 400 410 420 430 pF1KA1 EPYAVVVLLEKDLIVVDLTQSNFPIFENPYPMDIHESPVTCTAYFADCPPDLILVLYSIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EPYAVVVLLEKDLIVVDLTQSNFPIFENPYPMDIHESPVTCTAYFADCPPDLILVLYSIG 190 200 210 220 230 240 440 450 460 470 480 490 pF1KA1 VKHKKQGYSNKEWPISGGAWNLGAQTYPEIIITGHADGSIKFWDASAITLQMLYKLKTSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VKHKKQGYSNKEWPISGGAWNLGAQTYPEIIITGHADGSIKFWDASAITLQMLYKLKTSK 250 260 270 280 290 300 500 510 520 530 540 550 pF1KA1 VFEKQKVGEGKQTCEIVEEDPFAIQMIYWCPESRIFCVSGVSAYVIIYKFSRHEITTEIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VFEKQKVGEGKQTCEIVEEDPFAIQMIYWCPESRIFCVSGVSAYVIIYKFSRHEITTEIV 310 320 330 340 350 360 560 570 580 590 600 610 pF1KA1 SLEVRLQYDVEDIITPEPETSPPFPDLSAQLPSSRSLSGSTNTVASEGVTKDSIPCLNVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLEVRLQYDVEDIITPEPETSPPFPDLSAQLPSSRSLSGSTNTVASEGVTKDSIPCLNVK 370 380 390 400 410 420 620 630 640 650 660 670 pF1KA1 TRPVRMPPGYQAELVIQLVWVDGEPPQQITSLAVSSAYGIVAFGNCNGLAVVDFIQKTVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TRPVRMPPGYQAELVIQLVWVDGEPPQQITSLAVSSAYGIVAFGNCNGLAVVDFIQKTVL 430 440 450 460 470 480 680 690 700 710 720 730 pF1KA1 LSMGTIDLYRSSDLYQRQPRSPRKNKQFIADNFCMRGLSNFYPDLTKRIRTSYQSLTELN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSMGTIDLYRSSDLYQRQPRSPRKNKQFIADNFCMRGLSNFYPDLTKRIRTSYQSLTELN 490 500 510 520 530 540 740 750 760 770 780 790 pF1KA1 DSPVPLELERCKSPTSDHVNGHCTSPTSQSCSSGKRLSSADVSKVNRWGPGRPPFRKAQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DSPVPLELERCKSPTSDHVNGHCTSPTSQSCSSGKRLSSADVSKVNRWGPGRPPFRKAQS 550 560 570 580 590 600 800 810 820 830 840 850 pF1KA1 AACMEISLPVTTEENRENSYNRSRSSSISSIDKDSKEAITALYFMDSFARKNDSTISPCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AACMEISLPVTTEENRENSYNRSRSSSISSIDKDSKEAITALYFMDSFARKNDSTISPCL 610 620 630 640 650 660 860 870 880 890 900 910 pF1KA1 FVGTSLGMVLIISLNLPLADEQRFTEPVMVLPSGTFLSLKGAVLTFSCMDRMGGLMQPPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FVGTSLGMVLIISLNLPLADEQRFTEPVMVLPSGTFLSLKGAVLTFSCMDRMGGLMQPPY 670 680 690 700 710 720 920 930 940 950 960 970 pF1KA1 EVWRDPNNIDENEKSWRRKVVMNSSSASQEIGDHQYTIICSEKQAKVFSLPSQTCLYVHN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EVWRDPNNIDENEKSWRRKVVMNSSSASQEIGDHQYTIICSEKQAKVFSLPSQTCLYVHN 730 740 750 760 770 780 980 990 1000 1010 1020 1030 pF1KA1 ITETSFILQANVVVMCSSACLACFCANGHIMIMSLPSLRPMLDVNYLPLTDMRIARTFCF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ITETSFILQANVVVMCSSACLACFCANGHIMIMSLPSLRPMLDVNYLPLTDMRIARTFCF 790 800 810 820 830 840 1040 1050 1060 1070 1080 1090 pF1KA1 TNEGQALYLVSPTEIQRLTYSQEMCDNLQDMLGDLFTPIETPEAQNRGFLKGLFGGSGQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TNEGQALYLVSPTEIQRLTYSQEMCDNLQDMLGDLFTPIETPEAQNRGFLKGLFGGSGQT 850 860 870 880 890 900 1100 1110 1120 1130 1140 1150 pF1KA1 FDREELFGEASAGKASRSLAQHIPGPGSIEGMKGAAGGVMGELTRARIALDERGQRLGEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FDREELFGEASAGKASRSLAQHIPGPGSIEGMKGAAGGVMGELTRARIALDERGQRLGEL 910 920 930 940 950 960 1160 1170 1180 pF1KA1 EEKTAGMMTSAEAFSKHAHELMLKYKDKKWYQF ::::::::::::::::::::::::::::::::: XP_016 EEKTAGMMTSAEAFSKHAHELMLKYKDKKWYQF 970 980 990 >>XP_011511630 (OMIM: 609381) PREDICTED: syntaxin-bindin (825 aa) initn: 5460 init1: 5460 opt: 5460 Z-score: 4986.9 bits: 934.2 E(85289): 0 Smith-Waterman score: 5460; 99.9% identity (100.0% similar) in 817 aa overlap (370-1186:9-825) 340 350 360 370 380 390 pF1KA1 LTIMHGKAITVLEMDHPIVEFLTLCETPYPNEFQEPYAVVVLLEKDLIVVDLTQSNFPIF .::::::::::::::::::::::::::::: XP_011 MLAFQVLISEFQEPYAVVVLLEKDLIVVDLTQSNFPIF 10 20 30 400 410 420 430 440 450 pF1KA1 ENPYPMDIHESPVTCTAYFADCPPDLILVLYSIGVKHKKQGYSNKEWPISGGAWNLGAQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ENPYPMDIHESPVTCTAYFADCPPDLILVLYSIGVKHKKQGYSNKEWPISGGAWNLGAQT 40 50 60 70 80 90 460 470 480 490 500 510 pF1KA1 YPEIIITGHADGSIKFWDASAITLQMLYKLKTSKVFEKQKVGEGKQTCEIVEEDPFAIQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YPEIIITGHADGSIKFWDASAITLQMLYKLKTSKVFEKQKVGEGKQTCEIVEEDPFAIQM 100 110 120 130 140 150 520 530 540 550 560 570 pF1KA1 IYWCPESRIFCVSGVSAYVIIYKFSRHEITTEIVSLEVRLQYDVEDIITPEPETSPPFPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IYWCPESRIFCVSGVSAYVIIYKFSRHEITTEIVSLEVRLQYDVEDIITPEPETSPPFPD 160 170 180 190 200 210 580 590 600 610 620 630 pF1KA1 LSAQLPSSRSLSGSTNTVASEGVTKDSIPCLNVKTRPVRMPPGYQAELVIQLVWVDGEPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSAQLPSSRSLSGSTNTVASEGVTKDSIPCLNVKTRPVRMPPGYQAELVIQLVWVDGEPP 220 230 240 250 260 270 640 650 660 670 680 690 pF1KA1 QQITSLAVSSAYGIVAFGNCNGLAVVDFIQKTVLLSMGTIDLYRSSDLYQRQPRSPRKNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QQITSLAVSSAYGIVAFGNCNGLAVVDFIQKTVLLSMGTIDLYRSSDLYQRQPRSPRKNK 280 290 300 310 320 330 700 710 720 730 740 750 pF1KA1 QFIADNFCMRGLSNFYPDLTKRIRTSYQSLTELNDSPVPLELERCKSPTSDHVNGHCTSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QFIADNFCMRGLSNFYPDLTKRIRTSYQSLTELNDSPVPLELERCKSPTSDHVNGHCTSP 340 350 360 370 380 390 760 770 780 790 800 810 pF1KA1 TSQSCSSGKRLSSADVSKVNRWGPGRPPFRKAQSAACMEISLPVTTEENRENSYNRSRSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSQSCSSGKRLSSADVSKVNRWGPGRPPFRKAQSAACMEISLPVTTEENRENSYNRSRSS 400 410 420 430 440 450 820 830 840 850 860 870 pF1KA1 SISSIDKDSKEAITALYFMDSFARKNDSTISPCLFVGTSLGMVLIISLNLPLADEQRFTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SISSIDKDSKEAITALYFMDSFARKNDSTISPCLFVGTSLGMVLIISLNLPLADEQRFTE 460 470 480 490 500 510 880 890 900 910 920 930 pF1KA1 PVMVLPSGTFLSLKGAVLTFSCMDRMGGLMQPPYEVWRDPNNIDENEKSWRRKVVMNSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVMVLPSGTFLSLKGAVLTFSCMDRMGGLMQPPYEVWRDPNNIDENEKSWRRKVVMNSSS 520 530 540 550 560 570 940 950 960 970 980 990 pF1KA1 ASQEIGDHQYTIICSEKQAKVFSLPSQTCLYVHNITETSFILQANVVVMCSSACLACFCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASQEIGDHQYTIICSEKQAKVFSLPSQTCLYVHNITETSFILQANVVVMCSSACLACFCA 580 590 600 610 620 630 1000 1010 1020 1030 1040 1050 pF1KA1 NGHIMIMSLPSLRPMLDVNYLPLTDMRIARTFCFTNEGQALYLVSPTEIQRLTYSQEMCD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NGHIMIMSLPSLRPMLDVNYLPLTDMRIARTFCFTNEGQALYLVSPTEIQRLTYSQEMCD 640 650 660 670 680 690 1060 1070 1080 1090 1100 1110 pF1KA1 NLQDMLGDLFTPIETPEAQNRGFLKGLFGGSGQTFDREELFGEASAGKASRSLAQHIPGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NLQDMLGDLFTPIETPEAQNRGFLKGLFGGSGQTFDREELFGEASAGKASRSLAQHIPGP 700 710 720 730 740 750 1120 1130 1140 1150 1160 1170 pF1KA1 GSIEGMKGAAGGVMGELTRARIALDERGQRLGELEEKTAGMMTSAEAFSKHAHELMLKYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSIEGMKGAAGGVMGELTRARIALDERGQRLGELEEKTAGMMTSAEAFSKHAHELMLKYK 760 770 780 790 800 810 1180 pF1KA1 DKKWYQF ::::::: XP_011 DKKWYQF 820 >>XP_016863023 (OMIM: 609381) PREDICTED: syntaxin-bindin (739 aa) initn: 5007 init1: 4939 opt: 4939 Z-score: 4512.0 bits: 846.2 E(85289): 0 Smith-Waterman score: 4939; 98.9% identity (99.6% similar) in 738 aa overlap (1-738:1-738) 10 20 30 40 50 60 pF1KA1 MKKFNFRKVLDGLTASSPGSGSSSGSNSGGGAGSGSVHPAGTAGVLREEIQETLTSEYFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MKKFNFRKVLDGLTASSPGSGSSSGSNSGGGAGSGSVHPAGTAGVLREEIQETLTSEYFQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 ICKTVRHGFPHQPTALAFDPVQKILAIGTRTGAIRILGRPGVDCYCQHESGAAVLQLQFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ICKTVRHGFPHQPTALAFDPVQKILAIGTRTGAIRILGRPGVDCYCQHESGAAVLQLQFL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 INEGALVSASSDDTLHLWNLRQKRPAILHSLKFNRERITYCHLPFQSKWLYVGTERGNTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 INEGALVSASSDDTLHLWNLRQKRPAILHSLKFNRERITYCHLPFQSKWLYVGTERGNTH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 IVNIESFILSGYVIMWNKAIELSTKTHPGPVVHLSDSPRDEGKLLIGYENGTVVFWDLKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IVNIESFILSGYVIMWNKAIELSTKTHPGPVVHLSDSPRDEGKLLIGYENGTVVFWDLKS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 KRAELRVYYDEAIHSIDWHHEGKQFMCSHSDGSLTLWNLKSPSRPFQTTIPHGKSQREGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KRAELRVYYDEAIHSIDWHHEGKQFMCSHSDGSLTLWNLKSPSRPFQTTIPHGKSQREGR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 KSESCKPILKVEYKTCKNSEPFIIFSGGLSYDKACRRPSLTIMHGKAITVLEMDHPIVEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSESCKPILKVEYKTCKNSEPFIIFSGGLSYDKACRRPSLTIMHGKAITVLEMDHPIVEF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 LTLCETPYPNEFQEPYAVVVLLEKDLIVVDLTQSNFPIFENPYPMDIHESPVTCTAYFAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTLCETPYPNEFQEPYAVVVLLEKDLIVVDLTQSNFPIFENPYPMDIHESPVTCTAYFAD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 CPPDLILVLYSIGVKHKKQGYSNKEWPISGGAWNLGAQTYPEIIITGHADGSIKFWDASA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CPPDLILVLYSIGVKHKKQGYSNKEWPISGGAWNLGAQTYPEIIITGHADGSIKFWDASA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 ITLQMLYKLKTSKVFEKQKVGEGKQTCEIVEEDPFAIQMIYWCPESRIFCVSGVSAYVII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ITLQMLYKLKTSKVFEKQKVGEGKQTCEIVEEDPFAIQMIYWCPESRIFCVSGVSAYVII 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 YKFSRHEITTEIVSLEVRLQYDVEDIITPEPETSPPFPDLSAQLPSSRSLSGSTNTVASE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YKFSRHEITTEIVSLEVRLQYDVEDIITPEPETSPPFPDLSAQLPSSRSLSGSTNTVASE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 GVTKDSIPCLNVKTRPVRMPPGYQAELVIQLVWVDGEPPQQITSLAVSSAYGIVAFGNCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GVTKDSIPCLNVKTRPVRMPPGYQAELVIQLVWVDGEPPQQITSLAVSSAYGIVAFGNCN 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 GLAVVDFIQKTVLLSMGTIDLYRSSDLYQRQPRSPRKNKQFIADNFCMRGLSNFYPDLTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLAVVDFIQKTVLLSMGTIDLYRSSDLYQRQPRSPRKNKQFIADNFCMRGLSNFYPDLTK 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 RIRTSYQSLTELNDSPVPLELERCKSPTSDHVNGHCTSPTSQSCSSGKRLSSADVSKVNR :::::::: .... :.: XP_016 RIRTSYQSCQHFSSPPTPS 730 >>XP_011511633 (OMIM: 609381) PREDICTED: syntaxin-bindin (715 aa) initn: 4747 init1: 4747 opt: 4747 Z-score: 4337.0 bits: 813.8 E(85289): 0 Smith-Waterman score: 4747; 100.0% identity (100.0% similar) in 703 aa overlap (1-703:1-703) 10 20 30 40 50 60 pF1KA1 MKKFNFRKVLDGLTASSPGSGSSSGSNSGGGAGSGSVHPAGTAGVLREEIQETLTSEYFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKKFNFRKVLDGLTASSPGSGSSSGSNSGGGAGSGSVHPAGTAGVLREEIQETLTSEYFQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 ICKTVRHGFPHQPTALAFDPVQKILAIGTRTGAIRILGRPGVDCYCQHESGAAVLQLQFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ICKTVRHGFPHQPTALAFDPVQKILAIGTRTGAIRILGRPGVDCYCQHESGAAVLQLQFL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 INEGALVSASSDDTLHLWNLRQKRPAILHSLKFNRERITYCHLPFQSKWLYVGTERGNTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 INEGALVSASSDDTLHLWNLRQKRPAILHSLKFNRERITYCHLPFQSKWLYVGTERGNTH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 IVNIESFILSGYVIMWNKAIELSTKTHPGPVVHLSDSPRDEGKLLIGYENGTVVFWDLKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IVNIESFILSGYVIMWNKAIELSTKTHPGPVVHLSDSPRDEGKLLIGYENGTVVFWDLKS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 KRAELRVYYDEAIHSIDWHHEGKQFMCSHSDGSLTLWNLKSPSRPFQTTIPHGKSQREGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KRAELRVYYDEAIHSIDWHHEGKQFMCSHSDGSLTLWNLKSPSRPFQTTIPHGKSQREGR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 KSESCKPILKVEYKTCKNSEPFIIFSGGLSYDKACRRPSLTIMHGKAITVLEMDHPIVEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KSESCKPILKVEYKTCKNSEPFIIFSGGLSYDKACRRPSLTIMHGKAITVLEMDHPIVEF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 LTLCETPYPNEFQEPYAVVVLLEKDLIVVDLTQSNFPIFENPYPMDIHESPVTCTAYFAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LTLCETPYPNEFQEPYAVVVLLEKDLIVVDLTQSNFPIFENPYPMDIHESPVTCTAYFAD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 CPPDLILVLYSIGVKHKKQGYSNKEWPISGGAWNLGAQTYPEIIITGHADGSIKFWDASA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CPPDLILVLYSIGVKHKKQGYSNKEWPISGGAWNLGAQTYPEIIITGHADGSIKFWDASA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 ITLQMLYKLKTSKVFEKQKVGEGKQTCEIVEEDPFAIQMIYWCPESRIFCVSGVSAYVII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ITLQMLYKLKTSKVFEKQKVGEGKQTCEIVEEDPFAIQMIYWCPESRIFCVSGVSAYVII 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 YKFSRHEITTEIVSLEVRLQYDVEDIITPEPETSPPFPDLSAQLPSSRSLSGSTNTVASE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YKFSRHEITTEIVSLEVRLQYDVEDIITPEPETSPPFPDLSAQLPSSRSLSGSTNTVASE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 GVTKDSIPCLNVKTRPVRMPPGYQAELVIQLVWVDGEPPQQITSLAVSSAYGIVAFGNCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GVTKDSIPCLNVKTRPVRMPPGYQAELVIQLVWVDGEPPQQITSLAVSSAYGIVAFGNCN 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 GLAVVDFIQKTVLLSMGTIDLYRSSDLYQRQPRSPRKNKQFIADNFCMRGLSNFYPDLTK ::::::::::::::::::::::::::::::::::::::::::: XP_011 GLAVVDFIQKTVLLSMGTIDLYRSSDLYQRQPRSPRKNKQFIAGCQHFSSPPTPS 670 680 690 700 710 730 740 750 760 770 780 pF1KA1 RIRTSYQSLTELNDSPVPLELERCKSPTSDHVNGHCTSPTSQSCSSGKRLSSADVSKVNR >>XP_016863020 (OMIM: 609381) PREDICTED: syntaxin-bindin (1162 aa) initn: 7792 init1: 4747 opt: 4747 Z-score: 4334.0 bits: 813.9 E(85289): 0 Smith-Waterman score: 7748; 97.9% identity (98.0% similar) in 1186 aa overlap (1-1186:1-1162) 10 20 30 40 50 60 pF1KA1 MKKFNFRKVLDGLTASSPGSGSSSGSNSGGGAGSGSVHPAGTAGVLREEIQETLTSEYFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MKKFNFRKVLDGLTASSPGSGSSSGSNSGGGAGSGSVHPAGTAGVLREEIQETLTSEYFQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 ICKTVRHGFPHQPTALAFDPVQKILAIGTRTGAIRILGRPGVDCYCQHESGAAVLQLQFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ICKTVRHGFPHQPTALAFDPVQKILAIGTRTGAIRILGRPGVDCYCQHESGAAVLQLQFL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 INEGALVSASSDDTLHLWNLRQKRPAILHSLKFNRERITYCHLPFQSKWLYVGTERGNTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 INEGALVSASSDDTLHLWNLRQKRPAILHSLKFNRERITYCHLPFQSKWLYVGTERGNTH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 IVNIESFILSGYVIMWNKAIELSTKTHPGPVVHLSDSPRDEGKLLIGYENGTVVFWDLKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IVNIESFILSGYVIMWNKAIELSTKTHPGPVVHLSDSPRDEGKLLIGYENGTVVFWDLKS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 KRAELRVYYDEAIHSIDWHHEGKQFMCSHSDGSLTLWNLKSPSRPFQTTIPHGKSQREGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KRAELRVYYDEAIHSIDWHHEGKQFMCSHSDGSLTLWNLKSPSRPFQTTIPHGKSQREGR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 KSESCKPILKVEYKTCKNSEPFIIFSGGLSYDKACRRPSLTIMHGKAITVLEMDHPIVEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSESCKPILKVEYKTCKNSEPFIIFSGGLSYDKACRRPSLTIMHGKAITVLEMDHPIVEF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 LTLCETPYPNEFQEPYAVVVLLEKDLIVVDLTQSNFPIFENPYPMDIHESPVTCTAYFAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTLCETPYPNEFQEPYAVVVLLEKDLIVVDLTQSNFPIFENPYPMDIHESPVTCTAYFAD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 CPPDLILVLYSIGVKHKKQGYSNKEWPISGGAWNLGAQTYPEIIITGHADGSIKFWDASA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CPPDLILVLYSIGVKHKKQGYSNKEWPISGGAWNLGAQTYPEIIITGHADGSIKFWDASA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 ITLQMLYKLKTSKVFEKQKVGEGKQTCEIVEEDPFAIQMIYWCPESRIFCVSGVSAYVII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ITLQMLYKLKTSKVFEKQKVGEGKQTCEIVEEDPFAIQMIYWCPESRIFCVSGVSAYVII 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 YKFSRHEITTEIVSLEVRLQYDVEDIITPEPETSPPFPDLSAQLPSSRSLSGSTNTVASE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YKFSRHEITTEIVSLEVRLQYDVEDIITPEPETSPPFPDLSAQLPSSRSLSGSTNTVASE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 GVTKDSIPCLNVKTRPVRMPPGYQAELVIQLVWVDGEPPQQITSLAVSSAYGIVAFGNCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GVTKDSIPCLNVKTRPVRMPPGYQAELVIQLVWVDGEPPQQITSLAVSSAYGIVAFGNCN 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 GLAVVDFIQKTVLLSMGTIDLYRSSDLYQRQPRSPRKNKQFIADNFCMRGLSNFYPDLTK ::::::::::::::::::::::::::::::::::::::::::: XP_016 GLAVVDFIQKTVLLSMGTIDLYRSSDLYQRQPRSPRKNKQFIA----------------- 670 680 690 700 730 740 750 760 770 780 pF1KA1 RIRTSYQSLTELNDSPVPLELERCKSPTSDHVNGHCTSPTSQSCSSGKRLSSADVSKVNR .:::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 -------GLTELNDSPVPLELERCKSPTSDHVNGHCTSPTSQSCSSGKRLSSADVSKVNR 710 720 730 740 750 790 800 810 820 830 840 pF1KA1 WGPGRPPFRKAQSAACMEISLPVTTEENRENSYNRSRSSSISSIDKDSKEAITALYFMDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WGPGRPPFRKAQSAACMEISLPVTTEENRENSYNRSRSSSISSIDKDSKEAITALYFMDS 760 770 780 790 800 810 850 860 870 880 890 900 pF1KA1 FARKNDSTISPCLFVGTSLGMVLIISLNLPLADEQRFTEPVMVLPSGTFLSLKGAVLTFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FARKNDSTISPCLFVGTSLGMVLIISLNLPLADEQRFTEPVMVLPSGTFLSLKGAVLTFS 820 830 840 850 860 870 910 920 930 940 950 960 pF1KA1 CMDRMGGLMQPPYEVWRDPNNIDENEKSWRRKVVMNSSSASQEIGDHQYTIICSEKQAKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CMDRMGGLMQPPYEVWRDPNNIDENEKSWRRKVVMNSSSASQEIGDHQYTIICSEKQAKV 880 890 900 910 920 930 970 980 990 1000 1010 1020 pF1KA1 FSLPSQTCLYVHNITETSFILQANVVVMCSSACLACFCANGHIMIMSLPSLRPMLDVNYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FSLPSQTCLYVHNITETSFILQANVVVMCSSACLACFCANGHIMIMSLPSLRPMLDVNYL 940 950 960 970 980 990 1030 1040 1050 1060 1070 1080 pF1KA1 PLTDMRIARTFCFTNEGQALYLVSPTEIQRLTYSQEMCDNLQDMLGDLFTPIETPEAQNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLTDMRIARTFCFTNEGQALYLVSPTEIQRLTYSQEMCDNLQDMLGDLFTPIETPEAQNR 1000 1010 1020 1030 1040 1050 1090 1100 1110 1120 1130 1140 pF1KA1 GFLKGLFGGSGQTFDREELFGEASAGKASRSLAQHIPGPGSIEGMKGAAGGVMGELTRAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GFLKGLFGGSGQTFDREELFGEASAGKASRSLAQHIPGPGSIEGMKGAAGGVMGELTRAR 1060 1070 1080 1090 1100 1110 1150 1160 1170 1180 pF1KA1 IALDERGQRLGELEEKTAGMMTSAEAFSKHAHELMLKYKDKKWYQF :::::::::::::::::::::::::::::::::::::::::::::: XP_016 IALDERGQRLGELEEKTAGMMTSAEAFSKHAHELMLKYKDKKWYQF 1120 1130 1140 1150 1160 >>XP_016863021 (OMIM: 609381) PREDICTED: syntaxin-bindin (1162 aa) initn: 7792 init1: 4747 opt: 4747 Z-score: 4334.0 bits: 813.9 E(85289): 0 Smith-Waterman score: 7748; 97.9% identity (98.0% similar) in 1186 aa overlap (1-1186:1-1162) 10 20 30 40 50 60 pF1KA1 MKKFNFRKVLDGLTASSPGSGSSSGSNSGGGAGSGSVHPAGTAGVLREEIQETLTSEYFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MKKFNFRKVLDGLTASSPGSGSSSGSNSGGGAGSGSVHPAGTAGVLREEIQETLTSEYFQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 ICKTVRHGFPHQPTALAFDPVQKILAIGTRTGAIRILGRPGVDCYCQHESGAAVLQLQFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ICKTVRHGFPHQPTALAFDPVQKILAIGTRTGAIRILGRPGVDCYCQHESGAAVLQLQFL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 INEGALVSASSDDTLHLWNLRQKRPAILHSLKFNRERITYCHLPFQSKWLYVGTERGNTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 INEGALVSASSDDTLHLWNLRQKRPAILHSLKFNRERITYCHLPFQSKWLYVGTERGNTH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 IVNIESFILSGYVIMWNKAIELSTKTHPGPVVHLSDSPRDEGKLLIGYENGTVVFWDLKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IVNIESFILSGYVIMWNKAIELSTKTHPGPVVHLSDSPRDEGKLLIGYENGTVVFWDLKS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 KRAELRVYYDEAIHSIDWHHEGKQFMCSHSDGSLTLWNLKSPSRPFQTTIPHGKSQREGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KRAELRVYYDEAIHSIDWHHEGKQFMCSHSDGSLTLWNLKSPSRPFQTTIPHGKSQREGR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 KSESCKPILKVEYKTCKNSEPFIIFSGGLSYDKACRRPSLTIMHGKAITVLEMDHPIVEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSESCKPILKVEYKTCKNSEPFIIFSGGLSYDKACRRPSLTIMHGKAITVLEMDHPIVEF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 LTLCETPYPNEFQEPYAVVVLLEKDLIVVDLTQSNFPIFENPYPMDIHESPVTCTAYFAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTLCETPYPNEFQEPYAVVVLLEKDLIVVDLTQSNFPIFENPYPMDIHESPVTCTAYFAD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 CPPDLILVLYSIGVKHKKQGYSNKEWPISGGAWNLGAQTYPEIIITGHADGSIKFWDASA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CPPDLILVLYSIGVKHKKQGYSNKEWPISGGAWNLGAQTYPEIIITGHADGSIKFWDASA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 ITLQMLYKLKTSKVFEKQKVGEGKQTCEIVEEDPFAIQMIYWCPESRIFCVSGVSAYVII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ITLQMLYKLKTSKVFEKQKVGEGKQTCEIVEEDPFAIQMIYWCPESRIFCVSGVSAYVII 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 YKFSRHEITTEIVSLEVRLQYDVEDIITPEPETSPPFPDLSAQLPSSRSLSGSTNTVASE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YKFSRHEITTEIVSLEVRLQYDVEDIITPEPETSPPFPDLSAQLPSSRSLSGSTNTVASE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 GVTKDSIPCLNVKTRPVRMPPGYQAELVIQLVWVDGEPPQQITSLAVSSAYGIVAFGNCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GVTKDSIPCLNVKTRPVRMPPGYQAELVIQLVWVDGEPPQQITSLAVSSAYGIVAFGNCN 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 GLAVVDFIQKTVLLSMGTIDLYRSSDLYQRQPRSPRKNKQFIADNFCMRGLSNFYPDLTK ::::::::::::::::::::::::::::::::::::::::::: XP_016 GLAVVDFIQKTVLLSMGTIDLYRSSDLYQRQPRSPRKNKQFIA----------------- 670 680 690 700 730 740 750 760 770 780 pF1KA1 RIRTSYQSLTELNDSPVPLELERCKSPTSDHVNGHCTSPTSQSCSSGKRLSSADVSKVNR .:::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 -------GLTELNDSPVPLELERCKSPTSDHVNGHCTSPTSQSCSSGKRLSSADVSKVNR 710 720 730 740 750 790 800 810 820 830 840 pF1KA1 WGPGRPPFRKAQSAACMEISLPVTTEENRENSYNRSRSSSISSIDKDSKEAITALYFMDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WGPGRPPFRKAQSAACMEISLPVTTEENRENSYNRSRSSSISSIDKDSKEAITALYFMDS 760 770 780 790 800 810 850 860 870 880 890 900 pF1KA1 FARKNDSTISPCLFVGTSLGMVLIISLNLPLADEQRFTEPVMVLPSGTFLSLKGAVLTFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FARKNDSTISPCLFVGTSLGMVLIISLNLPLADEQRFTEPVMVLPSGTFLSLKGAVLTFS 820 830 840 850 860 870 910 920 930 940 950 960 pF1KA1 CMDRMGGLMQPPYEVWRDPNNIDENEKSWRRKVVMNSSSASQEIGDHQYTIICSEKQAKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CMDRMGGLMQPPYEVWRDPNNIDENEKSWRRKVVMNSSSASQEIGDHQYTIICSEKQAKV 880 890 900 910 920 930 970 980 990 1000 1010 1020 pF1KA1 FSLPSQTCLYVHNITETSFILQANVVVMCSSACLACFCANGHIMIMSLPSLRPMLDVNYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FSLPSQTCLYVHNITETSFILQANVVVMCSSACLACFCANGHIMIMSLPSLRPMLDVNYL 940 950 960 970 980 990 1030 1040 1050 1060 1070 1080 pF1KA1 PLTDMRIARTFCFTNEGQALYLVSPTEIQRLTYSQEMCDNLQDMLGDLFTPIETPEAQNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLTDMRIARTFCFTNEGQALYLVSPTEIQRLTYSQEMCDNLQDMLGDLFTPIETPEAQNR 1000 1010 1020 1030 1040 1050 1090 1100 1110 1120 1130 1140 pF1KA1 GFLKGLFGGSGQTFDREELFGEASAGKASRSLAQHIPGPGSIEGMKGAAGGVMGELTRAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GFLKGLFGGSGQTFDREELFGEASAGKASRSLAQHIPGPGSIEGMKGAAGGVMGELTRAR 1060 1070 1080 1090 1100 1110 1150 1160 1170 1180 pF1KA1 IALDERGQRLGELEEKTAGMMTSAEAFSKHAHELMLKYKDKKWYQF :::::::::::::::::::::::::::::::::::::::::::::: XP_016 IALDERGQRLGELEEKTAGMMTSAEAFSKHAHELMLKYKDKKWYQF 1120 1130 1140 1150 1160 >>NP_001295259 (OMIM: 609381) syntaxin-binding protein 5 (1162 aa) initn: 7792 init1: 4747 opt: 4747 Z-score: 4334.0 bits: 813.9 E(85289): 0 Smith-Waterman score: 7748; 97.9% identity (98.0% similar) in 1186 aa overlap (1-1186:1-1162) 10 20 30 40 50 60 pF1KA1 MKKFNFRKVLDGLTASSPGSGSSSGSNSGGGAGSGSVHPAGTAGVLREEIQETLTSEYFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKKFNFRKVLDGLTASSPGSGSSSGSNSGGGAGSGSVHPAGTAGVLREEIQETLTSEYFQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 ICKTVRHGFPHQPTALAFDPVQKILAIGTRTGAIRILGRPGVDCYCQHESGAAVLQLQFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ICKTVRHGFPHQPTALAFDPVQKILAIGTRTGAIRILGRPGVDCYCQHESGAAVLQLQFL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 INEGALVSASSDDTLHLWNLRQKRPAILHSLKFNRERITYCHLPFQSKWLYVGTERGNTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 INEGALVSASSDDTLHLWNLRQKRPAILHSLKFNRERITYCHLPFQSKWLYVGTERGNTH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 IVNIESFILSGYVIMWNKAIELSTKTHPGPVVHLSDSPRDEGKLLIGYENGTVVFWDLKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IVNIESFILSGYVIMWNKAIELSTKTHPGPVVHLSDSPRDEGKLLIGYENGTVVFWDLKS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 KRAELRVYYDEAIHSIDWHHEGKQFMCSHSDGSLTLWNLKSPSRPFQTTIPHGKSQREGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KRAELRVYYDEAIHSIDWHHEGKQFMCSHSDGSLTLWNLKSPSRPFQTTIPHGKSQREGR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 KSESCKPILKVEYKTCKNSEPFIIFSGGLSYDKACRRPSLTIMHGKAITVLEMDHPIVEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KSESCKPILKVEYKTCKNSEPFIIFSGGLSYDKACRRPSLTIMHGKAITVLEMDHPIVEF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 LTLCETPYPNEFQEPYAVVVLLEKDLIVVDLTQSNFPIFENPYPMDIHESPVTCTAYFAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LTLCETPYPNEFQEPYAVVVLLEKDLIVVDLTQSNFPIFENPYPMDIHESPVTCTAYFAD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 CPPDLILVLYSIGVKHKKQGYSNKEWPISGGAWNLGAQTYPEIIITGHADGSIKFWDASA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CPPDLILVLYSIGVKHKKQGYSNKEWPISGGAWNLGAQTYPEIIITGHADGSIKFWDASA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 ITLQMLYKLKTSKVFEKQKVGEGKQTCEIVEEDPFAIQMIYWCPESRIFCVSGVSAYVII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ITLQMLYKLKTSKVFEKQKVGEGKQTCEIVEEDPFAIQMIYWCPESRIFCVSGVSAYVII 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 YKFSRHEITTEIVSLEVRLQYDVEDIITPEPETSPPFPDLSAQLPSSRSLSGSTNTVASE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YKFSRHEITTEIVSLEVRLQYDVEDIITPEPETSPPFPDLSAQLPSSRSLSGSTNTVASE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 GVTKDSIPCLNVKTRPVRMPPGYQAELVIQLVWVDGEPPQQITSLAVSSAYGIVAFGNCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GVTKDSIPCLNVKTRPVRMPPGYQAELVIQLVWVDGEPPQQITSLAVSSAYGIVAFGNCN 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 GLAVVDFIQKTVLLSMGTIDLYRSSDLYQRQPRSPRKNKQFIADNFCMRGLSNFYPDLTK ::::::::::::::::::::::::::::::::::::::::::: NP_001 GLAVVDFIQKTVLLSMGTIDLYRSSDLYQRQPRSPRKNKQFIA----------------- 670 680 690 700 730 740 750 760 770 780 pF1KA1 RIRTSYQSLTELNDSPVPLELERCKSPTSDHVNGHCTSPTSQSCSSGKRLSSADVSKVNR .:::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 -------GLTELNDSPVPLELERCKSPTSDHVNGHCTSPTSQSCSSGKRLSSADVSKVNR 710 720 730 740 750 790 800 810 820 830 840 pF1KA1 WGPGRPPFRKAQSAACMEISLPVTTEENRENSYNRSRSSSISSIDKDSKEAITALYFMDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WGPGRPPFRKAQSAACMEISLPVTTEENRENSYNRSRSSSISSIDKDSKEAITALYFMDS 760 770 780 790 800 810 850 860 870 880 890 900 pF1KA1 FARKNDSTISPCLFVGTSLGMVLIISLNLPLADEQRFTEPVMVLPSGTFLSLKGAVLTFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FARKNDSTISPCLFVGTSLGMVLIISLNLPLADEQRFTEPVMVLPSGTFLSLKGAVLTFS 820 830 840 850 860 870 910 920 930 940 950 960 pF1KA1 CMDRMGGLMQPPYEVWRDPNNIDENEKSWRRKVVMNSSSASQEIGDHQYTIICSEKQAKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CMDRMGGLMQPPYEVWRDPNNIDENEKSWRRKVVMNSSSASQEIGDHQYTIICSEKQAKV 880 890 900 910 920 930 970 980 990 1000 1010 1020 pF1KA1 FSLPSQTCLYVHNITETSFILQANVVVMCSSACLACFCANGHIMIMSLPSLRPMLDVNYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FSLPSQTCLYVHNITETSFILQANVVVMCSSACLACFCANGHIMIMSLPSLRPMLDVNYL 940 950 960 970 980 990 1030 1040 1050 1060 1070 1080 pF1KA1 PLTDMRIARTFCFTNEGQALYLVSPTEIQRLTYSQEMCDNLQDMLGDLFTPIETPEAQNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLTDMRIARTFCFTNEGQALYLVSPTEIQRLTYSQEMCDNLQDMLGDLFTPIETPEAQNR 1000 1010 1020 1030 1040 1050 1090 1100 1110 1120 1130 1140 pF1KA1 GFLKGLFGGSGQTFDREELFGEASAGKASRSLAQHIPGPGSIEGMKGAAGGVMGELTRAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GFLKGLFGGSGQTFDREELFGEASAGKASRSLAQHIPGPGSIEGMKGAAGGVMGELTRAR 1060 1070 1080 1090 1100 1110 1150 1160 1170 1180 pF1KA1 IALDERGQRLGELEEKTAGMMTSAEAFSKHAHELMLKYKDKKWYQF :::::::::::::::::::::::::::::::::::::::::::::: NP_001 IALDERGQRLGELEEKTAGMMTSAEAFSKHAHELMLKYKDKKWYQF 1120 1130 1140 1150 1160 1186 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 01:16:03 2016 done: Fri Nov 4 01:16:05 2016 Total Scan time: 14.120 Total Display time: 0.560 Function used was FASTA [36.3.4 Apr, 2011]