FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1009, 1327 aa 1>>>pF1KA1009 1327 - 1327 aa - 1327 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 12.7012+/-0.000695; mu= -9.5438+/- 0.043 mean_var=645.5021+/-136.088, 0's: 0 Z-trim(114.9): 319 B-trim: 0 in 0/59 Lambda= 0.050481 statistics sampled from 24695 (24984) to 24695 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.595), E-opt: 0.2 (0.293), width: 16 Scan time: 16.760 The best scores are: opt bits E(85289) XP_006715443 (OMIM: 610201) PREDICTED: centrosomal (1327) 8381 627.8 1.6e-178 NP_001273135 (OMIM: 610201) centrosomal protein of (1327) 8381 627.8 1.6e-178 XP_016865973 (OMIM: 610201) PREDICTED: centrosomal (1327) 8381 627.8 1.6e-178 XP_016865972 (OMIM: 610201) PREDICTED: centrosomal (1365) 8381 627.8 1.6e-178 XP_005248731 (OMIM: 610201) PREDICTED: centrosomal (1365) 8381 627.8 1.6e-178 NP_055710 (OMIM: 610201) centrosomal protein of 16 (1403) 8381 627.8 1.6e-178 XP_011533894 (OMIM: 610201) PREDICTED: centrosomal (1014) 6409 484.0 2.3e-135 XP_005248735 (OMIM: 610201) PREDICTED: centrosomal ( 760) 4334 332.7 5.9e-90 XP_011533896 (OMIM: 610201) PREDICTED: centrosomal ( 761) 4334 332.7 5.9e-90 XP_016861684 (OMIM: 602500) PREDICTED: golgin subf (3016) 381 45.6 0.0065 NP_001243417 (OMIM: 602500) golgin subfamily B mem (3184) 381 45.6 0.0068 XP_016861683 (OMIM: 602500) PREDICTED: golgin subf (3189) 381 45.6 0.0068 XP_006713654 (OMIM: 602500) PREDICTED: golgin subf (3189) 381 45.6 0.0068 XP_006713653 (OMIM: 602500) PREDICTED: golgin subf (3223) 381 45.6 0.0068 XP_016861682 (OMIM: 602500) PREDICTED: golgin subf (3224) 381 45.6 0.0068 XP_016861681 (OMIM: 602500) PREDICTED: golgin subf (3225) 381 45.6 0.0068 NP_001243416 (OMIM: 602500) golgin subfamily B mem (3225) 381 45.6 0.0068 XP_005247430 (OMIM: 602500) PREDICTED: golgin subf (3228) 381 45.6 0.0068 XP_016861680 (OMIM: 602500) PREDICTED: golgin subf (3228) 381 45.6 0.0068 XP_005247429 (OMIM: 602500) PREDICTED: golgin subf (3230) 381 45.6 0.0068 NP_004478 (OMIM: 602500) golgin subfamily B member (3259) 381 45.6 0.0069 XP_016861679 (OMIM: 602500) PREDICTED: golgin subf (3263) 381 45.6 0.0069 XP_006713652 (OMIM: 602500) PREDICTED: golgin subf (3263) 381 45.6 0.0069 XP_006713651 (OMIM: 602500) PREDICTED: golgin subf (3264) 381 45.6 0.0069 XP_006713650 (OMIM: 602500) PREDICTED: golgin subf (3264) 381 45.6 0.0069 XP_016861678 (OMIM: 602500) PREDICTED: golgin subf (3264) 381 45.6 0.0069 XP_011511001 (OMIM: 602500) PREDICTED: golgin subf (3269) 381 45.6 0.0069 NP_001243415 (OMIM: 602500) golgin subfamily B mem (3269) 381 45.6 0.0069 XP_005247428 (OMIM: 602500) PREDICTED: golgin subf (3269) 381 45.6 0.0069 >>XP_006715443 (OMIM: 610201) PREDICTED: centrosomal pro (1327 aa) initn: 8381 init1: 8381 opt: 8381 Z-score: 3326.1 bits: 627.8 E(85289): 1.6e-178 Smith-Waterman score: 8381; 99.9% identity (99.9% similar) in 1327 aa overlap (1-1327:1-1327) 10 20 30 40 50 60 pF1KA1 MEIEEESAEKIQFLKSSGTSLLSTDSLETNELVVSELNHSSLGVGLDTLEEQEEKEQFFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MEIEEESAEKIQFLKSSGTSLLSTDSLETNELVVSELNHSSLGVGLDTLEEQEEKEQFFA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 RLEKGLTSSIDYSRLNKELDSNDSTHFKALHINQANAELTDDEHENESKHEELAENYSDD ::::::::::::::::::::::::::::::: :::::::::::::::::::::::::::: XP_006 RLEKGLTSSIDYSRLNKELDSNDSTHFKALHSNQANAELTDDEHENESKHEELAENYSDD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 FEDEYVGAPLTTKDEEMPSKENSKSEKISVPKQEEEKTGMLANVVLLDSLDSVAEVNLDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FEDEYVGAPLTTKDEEMPSKENSKSEKISVPKQEEEKTGMLANVVLLDSLDSVAEVNLDE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 QDKITPKPRCLPEMTENEMTGTGVSYGQSSSDVEALHQAYCHIAHSLGDEDKQKIESNTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QDKITPKPRCLPEMTENEMTGTGVSYGQSSSDVEALHQAYCHIAHSLGDEDKQKIESNTV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 EDIKSSVKGHPQENEENSKNISTMESDLPTVEELMKPIRIDSFGISGFDLQPVSSEKVAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EDIKSSVKGHPQENEENSKNISTMESDLPTVEELMKPIRIDSFGISGFDLQPVSSEKVAE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 RKETEFFSSLPLKMNPNILSQDSQHVNLFFDKNDENVILQKTTNESMENSCPQVTEVTAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RKETEFFSSLPLKMNPNILSQDSQHVNLFFDKNDENVILQKTTNESMENSCPQVTEVTAT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 EEHVDKMYLNILRKKITVNSSSLSQDDKINKTYRSQLSSEEEGAVMGKQVPYKKARSAPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EEHVDKMYLNILRKKITVNSSSLSQDDKINKTYRSQLSSEEEGAVMGKQVPYKKARSAPP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 LLKRKPQSGLYASVRSSGYGKPSSPLKMFSTLEKKTSEDIIKSKNLRSISTSNQPRKKEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LLKRKPQSGLYASVRSSGYGKPSSPLKMFSTLEKKTSEDIIKSKNLRSISTSNQPRKKEI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 LSGTKLIKPAALDKPAHKTESCLSTRKKSENPTETDSCIQFQTDSLGYCGENKEKKLLMF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LSGTKLIKPAALDKPAHKTESCLSTRKKSENPTETDSCIQFQTDSLGYCGENKEKKLLMF 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 KRVQEAEDKWRGAQALIEQIKATFSEKEKELENKLEELKKQQEKELFKLNQDNYILQAKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KRVQEAEDKWRGAQALIEQIKATFSEKEKELENKLEELKKQQEKELFKLNQDNYILQAKL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 SSFEETNKKQRWLHFGEAADPVTGEKLKQIQKEIQEQETLLQGYQQENERLYNQVKDLQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SSFEETNKKQRWLHFGEAADPVTGEKLKQIQKEIQEQETLLQGYQQENERLYNQVKDLQE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 QNKKNEERMFKENQSLFSEVASLKEQMHKSRFLSQVVEDSEPTRNQNFTDLLAELRMAQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QNKKNEERMFKENQSLFSEVASLKEQMHKSRFLSQVVEDSEPTRNQNFTDLLAELRMAQK 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 EKDSLLEDIKRLKQDKQALEVDFEKMKKERDQAKDQIAYVTGEKLYEIKILEETHKQEIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EKDSLLEDIKRLKQDKQALEVDFEKMKKERDQAKDQIAYVTGEKLYEIKILEETHKQEIS 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 RLQKRLQWYAENQELLDKDALRLREANEEIEKLKLEIEKLKAESGNPSIRQKIRLKDKAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RLQKRLQWYAENQELLDKDALRLREANEEIEKLKLEIEKLKAESGNPSIRQKIRLKDKAA 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 DAKKIQDLERQVKEMEGILKRRYPNSLPALILAASAAGDTVDKNTVEFMEKRIKKLEADL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DAKKIQDLERQVKEMEGILKRRYPNSLPALILAASAAGDTVDKNTVEFMEKRIKKLEADL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 EGKDEDAKKSLRTMEQQFQKMKIQYEQRLEQQEQLLACKLNQHDSPRIKALEKELDDIKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EGKDEDAKKSLRTMEQQFQKMKIQYEQRLEQQEQLLACKLNQHDSPRIKALEKELDDIKE 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 AHQITVRNLEAEIDVLKHQNAELDVKKNDKDDEDFQSIEFQVEQAHAKAKLVRLNEELAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AHQITVRNLEAEIDVLKHQNAELDVKKNDKDDEDFQSIEFQVEQAHAKAKLVRLNEELAA 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA1 KKREIQDLSKTVERLQKDRRMMLSNQNSKGREEMSAKRAKKDVLHSSKGNANSFPGTLDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KKREIQDLSKTVERLQKDRRMMLSNQNSKGREEMSAKRAKKDVLHSSKGNANSFPGTLDS 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA1 KLYQPHTFTDSHVSEVLQENYRLKNELEGLISEKNELKMKSEAVMNQFENSMRRVKEDTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KLYQPHTFTDSHVSEVLQENYRLKNELEGLISEKNELKMKSEAVMNQFENSMRRVKEDTA 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA1 AHIASLKASHQREIEKLLCQNAVENSSSKVAELNRKIATQEVLIRHFQSQVNELQSKQES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AHIASLKASHQREIEKLLCQNAVENSSSKVAELNRKIATQEVLIRHFQSQVNELQSKQES 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA1 LVVSEVREEILQKEITKLLEELREAKENHTPEMKHFVGLEKKIKQMEMRHAQREQELQQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LVVSEVREEILQKEITKLLEELREAKENHTPEMKHFVGLEKKIKQMEMRHAQREQELQQI 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA1 IQQTHQVVETEQNKEVEKWKRLAQLKNRELEKFRTELDSILDVLRELHRQGVVVPVAFAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IQQTHQVVETEQNKEVEKWKRLAQLKNRELEKFRTELDSILDVLRELHRQGVVVPVAFAD 1270 1280 1290 1300 1310 1320 pF1KA1 EMNAPEY ::::::: XP_006 EMNAPEY >>NP_001273135 (OMIM: 610201) centrosomal protein of 162 (1327 aa) initn: 8381 init1: 8381 opt: 8381 Z-score: 3326.1 bits: 627.8 E(85289): 1.6e-178 Smith-Waterman score: 8381; 99.9% identity (99.9% similar) in 1327 aa overlap (1-1327:1-1327) 10 20 30 40 50 60 pF1KA1 MEIEEESAEKIQFLKSSGTSLLSTDSLETNELVVSELNHSSLGVGLDTLEEQEEKEQFFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEIEEESAEKIQFLKSSGTSLLSTDSLETNELVVSELNHSSLGVGLDTLEEQEEKEQFFA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 RLEKGLTSSIDYSRLNKELDSNDSTHFKALHINQANAELTDDEHENESKHEELAENYSDD ::::::::::::::::::::::::::::::: :::::::::::::::::::::::::::: NP_001 RLEKGLTSSIDYSRLNKELDSNDSTHFKALHSNQANAELTDDEHENESKHEELAENYSDD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 FEDEYVGAPLTTKDEEMPSKENSKSEKISVPKQEEEKTGMLANVVLLDSLDSVAEVNLDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FEDEYVGAPLTTKDEEMPSKENSKSEKISVPKQEEEKTGMLANVVLLDSLDSVAEVNLDE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 QDKITPKPRCLPEMTENEMTGTGVSYGQSSSDVEALHQAYCHIAHSLGDEDKQKIESNTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QDKITPKPRCLPEMTENEMTGTGVSYGQSSSDVEALHQAYCHIAHSLGDEDKQKIESNTV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 EDIKSSVKGHPQENEENSKNISTMESDLPTVEELMKPIRIDSFGISGFDLQPVSSEKVAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDIKSSVKGHPQENEENSKNISTMESDLPTVEELMKPIRIDSFGISGFDLQPVSSEKVAE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 RKETEFFSSLPLKMNPNILSQDSQHVNLFFDKNDENVILQKTTNESMENSCPQVTEVTAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKETEFFSSLPLKMNPNILSQDSQHVNLFFDKNDENVILQKTTNESMENSCPQVTEVTAT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 EEHVDKMYLNILRKKITVNSSSLSQDDKINKTYRSQLSSEEEGAVMGKQVPYKKARSAPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEHVDKMYLNILRKKITVNSSSLSQDDKINKTYRSQLSSEEEGAVMGKQVPYKKARSAPP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 LLKRKPQSGLYASVRSSGYGKPSSPLKMFSTLEKKTSEDIIKSKNLRSISTSNQPRKKEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLKRKPQSGLYASVRSSGYGKPSSPLKMFSTLEKKTSEDIIKSKNLRSISTSNQPRKKEI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 LSGTKLIKPAALDKPAHKTESCLSTRKKSENPTETDSCIQFQTDSLGYCGENKEKKLLMF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSGTKLIKPAALDKPAHKTESCLSTRKKSENPTETDSCIQFQTDSLGYCGENKEKKLLMF 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 KRVQEAEDKWRGAQALIEQIKATFSEKEKELENKLEELKKQQEKELFKLNQDNYILQAKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KRVQEAEDKWRGAQALIEQIKATFSEKEKELENKLEELKKQQEKELFKLNQDNYILQAKL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 SSFEETNKKQRWLHFGEAADPVTGEKLKQIQKEIQEQETLLQGYQQENERLYNQVKDLQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSFEETNKKQRWLHFGEAADPVTGEKLKQIQKEIQEQETLLQGYQQENERLYNQVKDLQE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 QNKKNEERMFKENQSLFSEVASLKEQMHKSRFLSQVVEDSEPTRNQNFTDLLAELRMAQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QNKKNEERMFKENQSLFSEVASLKEQMHKSRFLSQVVEDSEPTRNQNFTDLLAELRMAQK 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 EKDSLLEDIKRLKQDKQALEVDFEKMKKERDQAKDQIAYVTGEKLYEIKILEETHKQEIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKDSLLEDIKRLKQDKQALEVDFEKMKKERDQAKDQIAYVTGEKLYEIKILEETHKQEIS 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 RLQKRLQWYAENQELLDKDALRLREANEEIEKLKLEIEKLKAESGNPSIRQKIRLKDKAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLQKRLQWYAENQELLDKDALRLREANEEIEKLKLEIEKLKAESGNPSIRQKIRLKDKAA 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 DAKKIQDLERQVKEMEGILKRRYPNSLPALILAASAAGDTVDKNTVEFMEKRIKKLEADL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DAKKIQDLERQVKEMEGILKRRYPNSLPALILAASAAGDTVDKNTVEFMEKRIKKLEADL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 EGKDEDAKKSLRTMEQQFQKMKIQYEQRLEQQEQLLACKLNQHDSPRIKALEKELDDIKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EGKDEDAKKSLRTMEQQFQKMKIQYEQRLEQQEQLLACKLNQHDSPRIKALEKELDDIKE 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 AHQITVRNLEAEIDVLKHQNAELDVKKNDKDDEDFQSIEFQVEQAHAKAKLVRLNEELAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AHQITVRNLEAEIDVLKHQNAELDVKKNDKDDEDFQSIEFQVEQAHAKAKLVRLNEELAA 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA1 KKREIQDLSKTVERLQKDRRMMLSNQNSKGREEMSAKRAKKDVLHSSKGNANSFPGTLDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KKREIQDLSKTVERLQKDRRMMLSNQNSKGREEMSAKRAKKDVLHSSKGNANSFPGTLDS 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA1 KLYQPHTFTDSHVSEVLQENYRLKNELEGLISEKNELKMKSEAVMNQFENSMRRVKEDTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLYQPHTFTDSHVSEVLQENYRLKNELEGLISEKNELKMKSEAVMNQFENSMRRVKEDTA 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA1 AHIASLKASHQREIEKLLCQNAVENSSSKVAELNRKIATQEVLIRHFQSQVNELQSKQES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AHIASLKASHQREIEKLLCQNAVENSSSKVAELNRKIATQEVLIRHFQSQVNELQSKQES 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA1 LVVSEVREEILQKEITKLLEELREAKENHTPEMKHFVGLEKKIKQMEMRHAQREQELQQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LVVSEVREEILQKEITKLLEELREAKENHTPEMKHFVGLEKKIKQMEMRHAQREQELQQI 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA1 IQQTHQVVETEQNKEVEKWKRLAQLKNRELEKFRTELDSILDVLRELHRQGVVVPVAFAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IQQTHQVVETEQNKEVEKWKRLAQLKNRELEKFRTELDSILDVLRELHRQGVVVPVAFAD 1270 1280 1290 1300 1310 1320 pF1KA1 EMNAPEY ::::::: NP_001 EMNAPEY >>XP_016865973 (OMIM: 610201) PREDICTED: centrosomal pro (1327 aa) initn: 8381 init1: 8381 opt: 8381 Z-score: 3326.1 bits: 627.8 E(85289): 1.6e-178 Smith-Waterman score: 8381; 99.9% identity (99.9% similar) in 1327 aa overlap (1-1327:1-1327) 10 20 30 40 50 60 pF1KA1 MEIEEESAEKIQFLKSSGTSLLSTDSLETNELVVSELNHSSLGVGLDTLEEQEEKEQFFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MEIEEESAEKIQFLKSSGTSLLSTDSLETNELVVSELNHSSLGVGLDTLEEQEEKEQFFA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 RLEKGLTSSIDYSRLNKELDSNDSTHFKALHINQANAELTDDEHENESKHEELAENYSDD ::::::::::::::::::::::::::::::: :::::::::::::::::::::::::::: XP_016 RLEKGLTSSIDYSRLNKELDSNDSTHFKALHSNQANAELTDDEHENESKHEELAENYSDD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 FEDEYVGAPLTTKDEEMPSKENSKSEKISVPKQEEEKTGMLANVVLLDSLDSVAEVNLDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FEDEYVGAPLTTKDEEMPSKENSKSEKISVPKQEEEKTGMLANVVLLDSLDSVAEVNLDE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 QDKITPKPRCLPEMTENEMTGTGVSYGQSSSDVEALHQAYCHIAHSLGDEDKQKIESNTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QDKITPKPRCLPEMTENEMTGTGVSYGQSSSDVEALHQAYCHIAHSLGDEDKQKIESNTV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 EDIKSSVKGHPQENEENSKNISTMESDLPTVEELMKPIRIDSFGISGFDLQPVSSEKVAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDIKSSVKGHPQENEENSKNISTMESDLPTVEELMKPIRIDSFGISGFDLQPVSSEKVAE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 RKETEFFSSLPLKMNPNILSQDSQHVNLFFDKNDENVILQKTTNESMENSCPQVTEVTAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RKETEFFSSLPLKMNPNILSQDSQHVNLFFDKNDENVILQKTTNESMENSCPQVTEVTAT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 EEHVDKMYLNILRKKITVNSSSLSQDDKINKTYRSQLSSEEEGAVMGKQVPYKKARSAPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEHVDKMYLNILRKKITVNSSSLSQDDKINKTYRSQLSSEEEGAVMGKQVPYKKARSAPP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 LLKRKPQSGLYASVRSSGYGKPSSPLKMFSTLEKKTSEDIIKSKNLRSISTSNQPRKKEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLKRKPQSGLYASVRSSGYGKPSSPLKMFSTLEKKTSEDIIKSKNLRSISTSNQPRKKEI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 LSGTKLIKPAALDKPAHKTESCLSTRKKSENPTETDSCIQFQTDSLGYCGENKEKKLLMF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSGTKLIKPAALDKPAHKTESCLSTRKKSENPTETDSCIQFQTDSLGYCGENKEKKLLMF 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 KRVQEAEDKWRGAQALIEQIKATFSEKEKELENKLEELKKQQEKELFKLNQDNYILQAKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KRVQEAEDKWRGAQALIEQIKATFSEKEKELENKLEELKKQQEKELFKLNQDNYILQAKL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 SSFEETNKKQRWLHFGEAADPVTGEKLKQIQKEIQEQETLLQGYQQENERLYNQVKDLQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSFEETNKKQRWLHFGEAADPVTGEKLKQIQKEIQEQETLLQGYQQENERLYNQVKDLQE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 QNKKNEERMFKENQSLFSEVASLKEQMHKSRFLSQVVEDSEPTRNQNFTDLLAELRMAQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QNKKNEERMFKENQSLFSEVASLKEQMHKSRFLSQVVEDSEPTRNQNFTDLLAELRMAQK 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 EKDSLLEDIKRLKQDKQALEVDFEKMKKERDQAKDQIAYVTGEKLYEIKILEETHKQEIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKDSLLEDIKRLKQDKQALEVDFEKMKKERDQAKDQIAYVTGEKLYEIKILEETHKQEIS 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 RLQKRLQWYAENQELLDKDALRLREANEEIEKLKLEIEKLKAESGNPSIRQKIRLKDKAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLQKRLQWYAENQELLDKDALRLREANEEIEKLKLEIEKLKAESGNPSIRQKIRLKDKAA 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 DAKKIQDLERQVKEMEGILKRRYPNSLPALILAASAAGDTVDKNTVEFMEKRIKKLEADL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DAKKIQDLERQVKEMEGILKRRYPNSLPALILAASAAGDTVDKNTVEFMEKRIKKLEADL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 EGKDEDAKKSLRTMEQQFQKMKIQYEQRLEQQEQLLACKLNQHDSPRIKALEKELDDIKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGKDEDAKKSLRTMEQQFQKMKIQYEQRLEQQEQLLACKLNQHDSPRIKALEKELDDIKE 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 AHQITVRNLEAEIDVLKHQNAELDVKKNDKDDEDFQSIEFQVEQAHAKAKLVRLNEELAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AHQITVRNLEAEIDVLKHQNAELDVKKNDKDDEDFQSIEFQVEQAHAKAKLVRLNEELAA 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA1 KKREIQDLSKTVERLQKDRRMMLSNQNSKGREEMSAKRAKKDVLHSSKGNANSFPGTLDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKREIQDLSKTVERLQKDRRMMLSNQNSKGREEMSAKRAKKDVLHSSKGNANSFPGTLDS 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA1 KLYQPHTFTDSHVSEVLQENYRLKNELEGLISEKNELKMKSEAVMNQFENSMRRVKEDTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLYQPHTFTDSHVSEVLQENYRLKNELEGLISEKNELKMKSEAVMNQFENSMRRVKEDTA 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA1 AHIASLKASHQREIEKLLCQNAVENSSSKVAELNRKIATQEVLIRHFQSQVNELQSKQES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AHIASLKASHQREIEKLLCQNAVENSSSKVAELNRKIATQEVLIRHFQSQVNELQSKQES 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA1 LVVSEVREEILQKEITKLLEELREAKENHTPEMKHFVGLEKKIKQMEMRHAQREQELQQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LVVSEVREEILQKEITKLLEELREAKENHTPEMKHFVGLEKKIKQMEMRHAQREQELQQI 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA1 IQQTHQVVETEQNKEVEKWKRLAQLKNRELEKFRTELDSILDVLRELHRQGVVVPVAFAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IQQTHQVVETEQNKEVEKWKRLAQLKNRELEKFRTELDSILDVLRELHRQGVVVPVAFAD 1270 1280 1290 1300 1310 1320 pF1KA1 EMNAPEY ::::::: XP_016 EMNAPEY >>XP_016865972 (OMIM: 610201) PREDICTED: centrosomal pro (1365 aa) initn: 8381 init1: 8381 opt: 8381 Z-score: 3326.0 bits: 627.8 E(85289): 1.6e-178 Smith-Waterman score: 8381; 99.9% identity (99.9% similar) in 1327 aa overlap (1-1327:39-1365) 10 20 30 pF1KA1 MEIEEESAEKIQFLKSSGTSLLSTDSLETN :::::::::::::::::::::::::::::: XP_016 WWITEDDFKDDGLLGTNVSYLKTKKTSQPVMEIEEESAEKIQFLKSSGTSLLSTDSLETN 10 20 30 40 50 60 40 50 60 70 80 90 pF1KA1 ELVVSELNHSSLGVGLDTLEEQEEKEQFFARLEKGLTSSIDYSRLNKELDSNDSTHFKAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELVVSELNHSSLGVGLDTLEEQEEKEQFFARLEKGLTSSIDYSRLNKELDSNDSTHFKAL 70 80 90 100 110 120 100 110 120 130 140 150 pF1KA1 HINQANAELTDDEHENESKHEELAENYSDDFEDEYVGAPLTTKDEEMPSKENSKSEKISV : :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HSNQANAELTDDEHENESKHEELAENYSDDFEDEYVGAPLTTKDEEMPSKENSKSEKISV 130 140 150 160 170 180 160 170 180 190 200 210 pF1KA1 PKQEEEKTGMLANVVLLDSLDSVAEVNLDEQDKITPKPRCLPEMTENEMTGTGVSYGQSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PKQEEEKTGMLANVVLLDSLDSVAEVNLDEQDKITPKPRCLPEMTENEMTGTGVSYGQSS 190 200 210 220 230 240 220 230 240 250 260 270 pF1KA1 SDVEALHQAYCHIAHSLGDEDKQKIESNTVEDIKSSVKGHPQENEENSKNISTMESDLPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDVEALHQAYCHIAHSLGDEDKQKIESNTVEDIKSSVKGHPQENEENSKNISTMESDLPT 250 260 270 280 290 300 280 290 300 310 320 330 pF1KA1 VEELMKPIRIDSFGISGFDLQPVSSEKVAERKETEFFSSLPLKMNPNILSQDSQHVNLFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VEELMKPIRIDSFGISGFDLQPVSSEKVAERKETEFFSSLPLKMNPNILSQDSQHVNLFF 310 320 330 340 350 360 340 350 360 370 380 390 pF1KA1 DKNDENVILQKTTNESMENSCPQVTEVTATEEHVDKMYLNILRKKITVNSSSLSQDDKIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DKNDENVILQKTTNESMENSCPQVTEVTATEEHVDKMYLNILRKKITVNSSSLSQDDKIN 370 380 390 400 410 420 400 410 420 430 440 450 pF1KA1 KTYRSQLSSEEEGAVMGKQVPYKKARSAPPLLKRKPQSGLYASVRSSGYGKPSSPLKMFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KTYRSQLSSEEEGAVMGKQVPYKKARSAPPLLKRKPQSGLYASVRSSGYGKPSSPLKMFS 430 440 450 460 470 480 460 470 480 490 500 510 pF1KA1 TLEKKTSEDIIKSKNLRSISTSNQPRKKEILSGTKLIKPAALDKPAHKTESCLSTRKKSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLEKKTSEDIIKSKNLRSISTSNQPRKKEILSGTKLIKPAALDKPAHKTESCLSTRKKSE 490 500 510 520 530 540 520 530 540 550 560 570 pF1KA1 NPTETDSCIQFQTDSLGYCGENKEKKLLMFKRVQEAEDKWRGAQALIEQIKATFSEKEKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NPTETDSCIQFQTDSLGYCGENKEKKLLMFKRVQEAEDKWRGAQALIEQIKATFSEKEKE 550 560 570 580 590 600 580 590 600 610 620 630 pF1KA1 LENKLEELKKQQEKELFKLNQDNYILQAKLSSFEETNKKQRWLHFGEAADPVTGEKLKQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LENKLEELKKQQEKELFKLNQDNYILQAKLSSFEETNKKQRWLHFGEAADPVTGEKLKQI 610 620 630 640 650 660 640 650 660 670 680 690 pF1KA1 QKEIQEQETLLQGYQQENERLYNQVKDLQEQNKKNEERMFKENQSLFSEVASLKEQMHKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QKEIQEQETLLQGYQQENERLYNQVKDLQEQNKKNEERMFKENQSLFSEVASLKEQMHKS 670 680 690 700 710 720 700 710 720 730 740 750 pF1KA1 RFLSQVVEDSEPTRNQNFTDLLAELRMAQKEKDSLLEDIKRLKQDKQALEVDFEKMKKER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RFLSQVVEDSEPTRNQNFTDLLAELRMAQKEKDSLLEDIKRLKQDKQALEVDFEKMKKER 730 740 750 760 770 780 760 770 780 790 800 810 pF1KA1 DQAKDQIAYVTGEKLYEIKILEETHKQEISRLQKRLQWYAENQELLDKDALRLREANEEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DQAKDQIAYVTGEKLYEIKILEETHKQEISRLQKRLQWYAENQELLDKDALRLREANEEI 790 800 810 820 830 840 820 830 840 850 860 870 pF1KA1 EKLKLEIEKLKAESGNPSIRQKIRLKDKAADAKKIQDLERQVKEMEGILKRRYPNSLPAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKLKLEIEKLKAESGNPSIRQKIRLKDKAADAKKIQDLERQVKEMEGILKRRYPNSLPAL 850 860 870 880 890 900 880 890 900 910 920 930 pF1KA1 ILAASAAGDTVDKNTVEFMEKRIKKLEADLEGKDEDAKKSLRTMEQQFQKMKIQYEQRLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILAASAAGDTVDKNTVEFMEKRIKKLEADLEGKDEDAKKSLRTMEQQFQKMKIQYEQRLE 910 920 930 940 950 960 940 950 960 970 980 990 pF1KA1 QQEQLLACKLNQHDSPRIKALEKELDDIKEAHQITVRNLEAEIDVLKHQNAELDVKKNDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QQEQLLACKLNQHDSPRIKALEKELDDIKEAHQITVRNLEAEIDVLKHQNAELDVKKNDK 970 980 990 1000 1010 1020 1000 1010 1020 1030 1040 1050 pF1KA1 DDEDFQSIEFQVEQAHAKAKLVRLNEELAAKKREIQDLSKTVERLQKDRRMMLSNQNSKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DDEDFQSIEFQVEQAHAKAKLVRLNEELAAKKREIQDLSKTVERLQKDRRMMLSNQNSKG 1030 1040 1050 1060 1070 1080 1060 1070 1080 1090 1100 1110 pF1KA1 REEMSAKRAKKDVLHSSKGNANSFPGTLDSKLYQPHTFTDSHVSEVLQENYRLKNELEGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REEMSAKRAKKDVLHSSKGNANSFPGTLDSKLYQPHTFTDSHVSEVLQENYRLKNELEGL 1090 1100 1110 1120 1130 1140 1120 1130 1140 1150 1160 1170 pF1KA1 ISEKNELKMKSEAVMNQFENSMRRVKEDTAAHIASLKASHQREIEKLLCQNAVENSSSKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISEKNELKMKSEAVMNQFENSMRRVKEDTAAHIASLKASHQREIEKLLCQNAVENSSSKV 1150 1160 1170 1180 1190 1200 1180 1190 1200 1210 1220 1230 pF1KA1 AELNRKIATQEVLIRHFQSQVNELQSKQESLVVSEVREEILQKEITKLLEELREAKENHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AELNRKIATQEVLIRHFQSQVNELQSKQESLVVSEVREEILQKEITKLLEELREAKENHT 1210 1220 1230 1240 1250 1260 1240 1250 1260 1270 1280 1290 pF1KA1 PEMKHFVGLEKKIKQMEMRHAQREQELQQIIQQTHQVVETEQNKEVEKWKRLAQLKNREL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PEMKHFVGLEKKIKQMEMRHAQREQELQQIIQQTHQVVETEQNKEVEKWKRLAQLKNREL 1270 1280 1290 1300 1310 1320 1300 1310 1320 pF1KA1 EKFRTELDSILDVLRELHRQGVVVPVAFADEMNAPEY ::::::::::::::::::::::::::::::::::::: XP_016 EKFRTELDSILDVLRELHRQGVVVPVAFADEMNAPEY 1330 1340 1350 1360 >>XP_005248731 (OMIM: 610201) PREDICTED: centrosomal pro (1365 aa) initn: 8381 init1: 8381 opt: 8381 Z-score: 3326.0 bits: 627.8 E(85289): 1.6e-178 Smith-Waterman score: 8381; 99.9% identity (99.9% similar) in 1327 aa overlap (1-1327:39-1365) 10 20 30 pF1KA1 MEIEEESAEKIQFLKSSGTSLLSTDSLETN :::::::::::::::::::::::::::::: XP_005 WWITEDDFKDDGLLGTNVSYLKTKKTSQPVMEIEEESAEKIQFLKSSGTSLLSTDSLETN 10 20 30 40 50 60 40 50 60 70 80 90 pF1KA1 ELVVSELNHSSLGVGLDTLEEQEEKEQFFARLEKGLTSSIDYSRLNKELDSNDSTHFKAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ELVVSELNHSSLGVGLDTLEEQEEKEQFFARLEKGLTSSIDYSRLNKELDSNDSTHFKAL 70 80 90 100 110 120 100 110 120 130 140 150 pF1KA1 HINQANAELTDDEHENESKHEELAENYSDDFEDEYVGAPLTTKDEEMPSKENSKSEKISV : :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HSNQANAELTDDEHENESKHEELAENYSDDFEDEYVGAPLTTKDEEMPSKENSKSEKISV 130 140 150 160 170 180 160 170 180 190 200 210 pF1KA1 PKQEEEKTGMLANVVLLDSLDSVAEVNLDEQDKITPKPRCLPEMTENEMTGTGVSYGQSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PKQEEEKTGMLANVVLLDSLDSVAEVNLDEQDKITPKPRCLPEMTENEMTGTGVSYGQSS 190 200 210 220 230 240 220 230 240 250 260 270 pF1KA1 SDVEALHQAYCHIAHSLGDEDKQKIESNTVEDIKSSVKGHPQENEENSKNISTMESDLPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SDVEALHQAYCHIAHSLGDEDKQKIESNTVEDIKSSVKGHPQENEENSKNISTMESDLPT 250 260 270 280 290 300 280 290 300 310 320 330 pF1KA1 VEELMKPIRIDSFGISGFDLQPVSSEKVAERKETEFFSSLPLKMNPNILSQDSQHVNLFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VEELMKPIRIDSFGISGFDLQPVSSEKVAERKETEFFSSLPLKMNPNILSQDSQHVNLFF 310 320 330 340 350 360 340 350 360 370 380 390 pF1KA1 DKNDENVILQKTTNESMENSCPQVTEVTATEEHVDKMYLNILRKKITVNSSSLSQDDKIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DKNDENVILQKTTNESMENSCPQVTEVTATEEHVDKMYLNILRKKITVNSSSLSQDDKIN 370 380 390 400 410 420 400 410 420 430 440 450 pF1KA1 KTYRSQLSSEEEGAVMGKQVPYKKARSAPPLLKRKPQSGLYASVRSSGYGKPSSPLKMFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KTYRSQLSSEEEGAVMGKQVPYKKARSAPPLLKRKPQSGLYASVRSSGYGKPSSPLKMFS 430 440 450 460 470 480 460 470 480 490 500 510 pF1KA1 TLEKKTSEDIIKSKNLRSISTSNQPRKKEILSGTKLIKPAALDKPAHKTESCLSTRKKSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TLEKKTSEDIIKSKNLRSISTSNQPRKKEILSGTKLIKPAALDKPAHKTESCLSTRKKSE 490 500 510 520 530 540 520 530 540 550 560 570 pF1KA1 NPTETDSCIQFQTDSLGYCGENKEKKLLMFKRVQEAEDKWRGAQALIEQIKATFSEKEKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NPTETDSCIQFQTDSLGYCGENKEKKLLMFKRVQEAEDKWRGAQALIEQIKATFSEKEKE 550 560 570 580 590 600 580 590 600 610 620 630 pF1KA1 LENKLEELKKQQEKELFKLNQDNYILQAKLSSFEETNKKQRWLHFGEAADPVTGEKLKQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LENKLEELKKQQEKELFKLNQDNYILQAKLSSFEETNKKQRWLHFGEAADPVTGEKLKQI 610 620 630 640 650 660 640 650 660 670 680 690 pF1KA1 QKEIQEQETLLQGYQQENERLYNQVKDLQEQNKKNEERMFKENQSLFSEVASLKEQMHKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QKEIQEQETLLQGYQQENERLYNQVKDLQEQNKKNEERMFKENQSLFSEVASLKEQMHKS 670 680 690 700 710 720 700 710 720 730 740 750 pF1KA1 RFLSQVVEDSEPTRNQNFTDLLAELRMAQKEKDSLLEDIKRLKQDKQALEVDFEKMKKER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RFLSQVVEDSEPTRNQNFTDLLAELRMAQKEKDSLLEDIKRLKQDKQALEVDFEKMKKER 730 740 750 760 770 780 760 770 780 790 800 810 pF1KA1 DQAKDQIAYVTGEKLYEIKILEETHKQEISRLQKRLQWYAENQELLDKDALRLREANEEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DQAKDQIAYVTGEKLYEIKILEETHKQEISRLQKRLQWYAENQELLDKDALRLREANEEI 790 800 810 820 830 840 820 830 840 850 860 870 pF1KA1 EKLKLEIEKLKAESGNPSIRQKIRLKDKAADAKKIQDLERQVKEMEGILKRRYPNSLPAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EKLKLEIEKLKAESGNPSIRQKIRLKDKAADAKKIQDLERQVKEMEGILKRRYPNSLPAL 850 860 870 880 890 900 880 890 900 910 920 930 pF1KA1 ILAASAAGDTVDKNTVEFMEKRIKKLEADLEGKDEDAKKSLRTMEQQFQKMKIQYEQRLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ILAASAAGDTVDKNTVEFMEKRIKKLEADLEGKDEDAKKSLRTMEQQFQKMKIQYEQRLE 910 920 930 940 950 960 940 950 960 970 980 990 pF1KA1 QQEQLLACKLNQHDSPRIKALEKELDDIKEAHQITVRNLEAEIDVLKHQNAELDVKKNDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QQEQLLACKLNQHDSPRIKALEKELDDIKEAHQITVRNLEAEIDVLKHQNAELDVKKNDK 970 980 990 1000 1010 1020 1000 1010 1020 1030 1040 1050 pF1KA1 DDEDFQSIEFQVEQAHAKAKLVRLNEELAAKKREIQDLSKTVERLQKDRRMMLSNQNSKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DDEDFQSIEFQVEQAHAKAKLVRLNEELAAKKREIQDLSKTVERLQKDRRMMLSNQNSKG 1030 1040 1050 1060 1070 1080 1060 1070 1080 1090 1100 1110 pF1KA1 REEMSAKRAKKDVLHSSKGNANSFPGTLDSKLYQPHTFTDSHVSEVLQENYRLKNELEGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 REEMSAKRAKKDVLHSSKGNANSFPGTLDSKLYQPHTFTDSHVSEVLQENYRLKNELEGL 1090 1100 1110 1120 1130 1140 1120 1130 1140 1150 1160 1170 pF1KA1 ISEKNELKMKSEAVMNQFENSMRRVKEDTAAHIASLKASHQREIEKLLCQNAVENSSSKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ISEKNELKMKSEAVMNQFENSMRRVKEDTAAHIASLKASHQREIEKLLCQNAVENSSSKV 1150 1160 1170 1180 1190 1200 1180 1190 1200 1210 1220 1230 pF1KA1 AELNRKIATQEVLIRHFQSQVNELQSKQESLVVSEVREEILQKEITKLLEELREAKENHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AELNRKIATQEVLIRHFQSQVNELQSKQESLVVSEVREEILQKEITKLLEELREAKENHT 1210 1220 1230 1240 1250 1260 1240 1250 1260 1270 1280 1290 pF1KA1 PEMKHFVGLEKKIKQMEMRHAQREQELQQIIQQTHQVVETEQNKEVEKWKRLAQLKNREL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PEMKHFVGLEKKIKQMEMRHAQREQELQQIIQQTHQVVETEQNKEVEKWKRLAQLKNREL 1270 1280 1290 1300 1310 1320 1300 1310 1320 pF1KA1 EKFRTELDSILDVLRELHRQGVVVPVAFADEMNAPEY ::::::::::::::::::::::::::::::::::::: XP_005 EKFRTELDSILDVLRELHRQGVVVPVAFADEMNAPEY 1330 1340 1350 1360 >>NP_055710 (OMIM: 610201) centrosomal protein of 162 kD (1403 aa) initn: 8381 init1: 8381 opt: 8381 Z-score: 3325.8 bits: 627.8 E(85289): 1.6e-178 Smith-Waterman score: 8381; 99.9% identity (99.9% similar) in 1327 aa overlap (1-1327:77-1403) 10 20 30 pF1KA1 MEIEEESAEKIQFLKSSGTSLLSTDSLETN :::::::::::::::::::::::::::::: NP_055 WWITEDDFKDDGLLGTNVSYLKTKKTSQPVMEIEEESAEKIQFLKSSGTSLLSTDSLETN 50 60 70 80 90 100 40 50 60 70 80 90 pF1KA1 ELVVSELNHSSLGVGLDTLEEQEEKEQFFARLEKGLTSSIDYSRLNKELDSNDSTHFKAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ELVVSELNHSSLGVGLDTLEEQEEKEQFFARLEKGLTSSIDYSRLNKELDSNDSTHFKAL 110 120 130 140 150 160 100 110 120 130 140 150 pF1KA1 HINQANAELTDDEHENESKHEELAENYSDDFEDEYVGAPLTTKDEEMPSKENSKSEKISV : :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 HSNQANAELTDDEHENESKHEELAENYSDDFEDEYVGAPLTTKDEEMPSKENSKSEKISV 170 180 190 200 210 220 160 170 180 190 200 210 pF1KA1 PKQEEEKTGMLANVVLLDSLDSVAEVNLDEQDKITPKPRCLPEMTENEMTGTGVSYGQSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PKQEEEKTGMLANVVLLDSLDSVAEVNLDEQDKITPKPRCLPEMTENEMTGTGVSYGQSS 230 240 250 260 270 280 220 230 240 250 260 270 pF1KA1 SDVEALHQAYCHIAHSLGDEDKQKIESNTVEDIKSSVKGHPQENEENSKNISTMESDLPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SDVEALHQAYCHIAHSLGDEDKQKIESNTVEDIKSSVKGHPQENEENSKNISTMESDLPT 290 300 310 320 330 340 280 290 300 310 320 330 pF1KA1 VEELMKPIRIDSFGISGFDLQPVSSEKVAERKETEFFSSLPLKMNPNILSQDSQHVNLFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VEELMKPIRIDSFGISGFDLQPVSSEKVAERKETEFFSSLPLKMNPNILSQDSQHVNLFF 350 360 370 380 390 400 340 350 360 370 380 390 pF1KA1 DKNDENVILQKTTNESMENSCPQVTEVTATEEHVDKMYLNILRKKITVNSSSLSQDDKIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 DKNDENVILQKTTNESMENSCPQVTEVTATEEHVDKMYLNILRKKITVNSSSLSQDDKIN 410 420 430 440 450 460 400 410 420 430 440 450 pF1KA1 KTYRSQLSSEEEGAVMGKQVPYKKARSAPPLLKRKPQSGLYASVRSSGYGKPSSPLKMFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KTYRSQLSSEEEGAVMGKQVPYKKARSAPPLLKRKPQSGLYASVRSSGYGKPSSPLKMFS 470 480 490 500 510 520 460 470 480 490 500 510 pF1KA1 TLEKKTSEDIIKSKNLRSISTSNQPRKKEILSGTKLIKPAALDKPAHKTESCLSTRKKSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TLEKKTSEDIIKSKNLRSISTSNQPRKKEILSGTKLIKPAALDKPAHKTESCLSTRKKSE 530 540 550 560 570 580 520 530 540 550 560 570 pF1KA1 NPTETDSCIQFQTDSLGYCGENKEKKLLMFKRVQEAEDKWRGAQALIEQIKATFSEKEKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 NPTETDSCIQFQTDSLGYCGENKEKKLLMFKRVQEAEDKWRGAQALIEQIKATFSEKEKE 590 600 610 620 630 640 580 590 600 610 620 630 pF1KA1 LENKLEELKKQQEKELFKLNQDNYILQAKLSSFEETNKKQRWLHFGEAADPVTGEKLKQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LENKLEELKKQQEKELFKLNQDNYILQAKLSSFEETNKKQRWLHFGEAADPVTGEKLKQI 650 660 670 680 690 700 640 650 660 670 680 690 pF1KA1 QKEIQEQETLLQGYQQENERLYNQVKDLQEQNKKNEERMFKENQSLFSEVASLKEQMHKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 QKEIQEQETLLQGYQQENERLYNQVKDLQEQNKKNEERMFKENQSLFSEVASLKEQMHKS 710 720 730 740 750 760 700 710 720 730 740 750 pF1KA1 RFLSQVVEDSEPTRNQNFTDLLAELRMAQKEKDSLLEDIKRLKQDKQALEVDFEKMKKER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 RFLSQVVEDSEPTRNQNFTDLLAELRMAQKEKDSLLEDIKRLKQDKQALEVDFEKMKKER 770 780 790 800 810 820 760 770 780 790 800 810 pF1KA1 DQAKDQIAYVTGEKLYEIKILEETHKQEISRLQKRLQWYAENQELLDKDALRLREANEEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 DQAKDQIAYVTGEKLYEIKILEETHKQEISRLQKRLQWYAENQELLDKDALRLREANEEI 830 840 850 860 870 880 820 830 840 850 860 870 pF1KA1 EKLKLEIEKLKAESGNPSIRQKIRLKDKAADAKKIQDLERQVKEMEGILKRRYPNSLPAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EKLKLEIEKLKAESGNPSIRQKIRLKDKAADAKKIQDLERQVKEMEGILKRRYPNSLPAL 890 900 910 920 930 940 880 890 900 910 920 930 pF1KA1 ILAASAAGDTVDKNTVEFMEKRIKKLEADLEGKDEDAKKSLRTMEQQFQKMKIQYEQRLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ILAASAAGDTVDKNTVEFMEKRIKKLEADLEGKDEDAKKSLRTMEQQFQKMKIQYEQRLE 950 960 970 980 990 1000 940 950 960 970 980 990 pF1KA1 QQEQLLACKLNQHDSPRIKALEKELDDIKEAHQITVRNLEAEIDVLKHQNAELDVKKNDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 QQEQLLACKLNQHDSPRIKALEKELDDIKEAHQITVRNLEAEIDVLKHQNAELDVKKNDK 1010 1020 1030 1040 1050 1060 1000 1010 1020 1030 1040 1050 pF1KA1 DDEDFQSIEFQVEQAHAKAKLVRLNEELAAKKREIQDLSKTVERLQKDRRMMLSNQNSKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 DDEDFQSIEFQVEQAHAKAKLVRLNEELAAKKREIQDLSKTVERLQKDRRMMLSNQNSKG 1070 1080 1090 1100 1110 1120 1060 1070 1080 1090 1100 1110 pF1KA1 REEMSAKRAKKDVLHSSKGNANSFPGTLDSKLYQPHTFTDSHVSEVLQENYRLKNELEGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 REEMSAKRAKKDVLHSSKGNANSFPGTLDSKLYQPHTFTDSHVSEVLQENYRLKNELEGL 1130 1140 1150 1160 1170 1180 1120 1130 1140 1150 1160 1170 pF1KA1 ISEKNELKMKSEAVMNQFENSMRRVKEDTAAHIASLKASHQREIEKLLCQNAVENSSSKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ISEKNELKMKSEAVMNQFENSMRRVKEDTAAHIASLKASHQREIEKLLCQNAVENSSSKV 1190 1200 1210 1220 1230 1240 1180 1190 1200 1210 1220 1230 pF1KA1 AELNRKIATQEVLIRHFQSQVNELQSKQESLVVSEVREEILQKEITKLLEELREAKENHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 AELNRKIATQEVLIRHFQSQVNELQSKQESLVVSEVREEILQKEITKLLEELREAKENHT 1250 1260 1270 1280 1290 1300 1240 1250 1260 1270 1280 1290 pF1KA1 PEMKHFVGLEKKIKQMEMRHAQREQELQQIIQQTHQVVETEQNKEVEKWKRLAQLKNREL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PEMKHFVGLEKKIKQMEMRHAQREQELQQIIQQTHQVVETEQNKEVEKWKRLAQLKNREL 1310 1320 1330 1340 1350 1360 1300 1310 1320 pF1KA1 EKFRTELDSILDVLRELHRQGVVVPVAFADEMNAPEY ::::::::::::::::::::::::::::::::::::: NP_055 EKFRTELDSILDVLRELHRQGVVVPVAFADEMNAPEY 1370 1380 1390 1400 >>XP_011533894 (OMIM: 610201) PREDICTED: centrosomal pro (1014 aa) initn: 6409 init1: 6409 opt: 6409 Z-score: 2551.3 bits: 484.0 E(85289): 2.3e-135 Smith-Waterman score: 6409; 100.0% identity (100.0% similar) in 1014 aa overlap (314-1327:1-1014) 290 300 310 320 330 340 pF1KA1 GISGFDLQPVSSEKVAERKETEFFSSLPLKMNPNILSQDSQHVNLFFDKNDENVILQKTT :::::::::::::::::::::::::::::: XP_011 MNPNILSQDSQHVNLFFDKNDENVILQKTT 10 20 30 350 360 370 380 390 400 pF1KA1 NESMENSCPQVTEVTATEEHVDKMYLNILRKKITVNSSSLSQDDKINKTYRSQLSSEEEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NESMENSCPQVTEVTATEEHVDKMYLNILRKKITVNSSSLSQDDKINKTYRSQLSSEEEG 40 50 60 70 80 90 410 420 430 440 450 460 pF1KA1 AVMGKQVPYKKARSAPPLLKRKPQSGLYASVRSSGYGKPSSPLKMFSTLEKKTSEDIIKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AVMGKQVPYKKARSAPPLLKRKPQSGLYASVRSSGYGKPSSPLKMFSTLEKKTSEDIIKS 100 110 120 130 140 150 470 480 490 500 510 520 pF1KA1 KNLRSISTSNQPRKKEILSGTKLIKPAALDKPAHKTESCLSTRKKSENPTETDSCIQFQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KNLRSISTSNQPRKKEILSGTKLIKPAALDKPAHKTESCLSTRKKSENPTETDSCIQFQT 160 170 180 190 200 210 530 540 550 560 570 580 pF1KA1 DSLGYCGENKEKKLLMFKRVQEAEDKWRGAQALIEQIKATFSEKEKELENKLEELKKQQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DSLGYCGENKEKKLLMFKRVQEAEDKWRGAQALIEQIKATFSEKEKELENKLEELKKQQE 220 230 240 250 260 270 590 600 610 620 630 640 pF1KA1 KELFKLNQDNYILQAKLSSFEETNKKQRWLHFGEAADPVTGEKLKQIQKEIQEQETLLQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KELFKLNQDNYILQAKLSSFEETNKKQRWLHFGEAADPVTGEKLKQIQKEIQEQETLLQG 280 290 300 310 320 330 650 660 670 680 690 700 pF1KA1 YQQENERLYNQVKDLQEQNKKNEERMFKENQSLFSEVASLKEQMHKSRFLSQVVEDSEPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YQQENERLYNQVKDLQEQNKKNEERMFKENQSLFSEVASLKEQMHKSRFLSQVVEDSEPT 340 350 360 370 380 390 710 720 730 740 750 760 pF1KA1 RNQNFTDLLAELRMAQKEKDSLLEDIKRLKQDKQALEVDFEKMKKERDQAKDQIAYVTGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RNQNFTDLLAELRMAQKEKDSLLEDIKRLKQDKQALEVDFEKMKKERDQAKDQIAYVTGE 400 410 420 430 440 450 770 780 790 800 810 820 pF1KA1 KLYEIKILEETHKQEISRLQKRLQWYAENQELLDKDALRLREANEEIEKLKLEIEKLKAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLYEIKILEETHKQEISRLQKRLQWYAENQELLDKDALRLREANEEIEKLKLEIEKLKAE 460 470 480 490 500 510 830 840 850 860 870 880 pF1KA1 SGNPSIRQKIRLKDKAADAKKIQDLERQVKEMEGILKRRYPNSLPALILAASAAGDTVDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGNPSIRQKIRLKDKAADAKKIQDLERQVKEMEGILKRRYPNSLPALILAASAAGDTVDK 520 530 540 550 560 570 890 900 910 920 930 940 pF1KA1 NTVEFMEKRIKKLEADLEGKDEDAKKSLRTMEQQFQKMKIQYEQRLEQQEQLLACKLNQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NTVEFMEKRIKKLEADLEGKDEDAKKSLRTMEQQFQKMKIQYEQRLEQQEQLLACKLNQH 580 590 600 610 620 630 950 960 970 980 990 1000 pF1KA1 DSPRIKALEKELDDIKEAHQITVRNLEAEIDVLKHQNAELDVKKNDKDDEDFQSIEFQVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DSPRIKALEKELDDIKEAHQITVRNLEAEIDVLKHQNAELDVKKNDKDDEDFQSIEFQVE 640 650 660 670 680 690 1010 1020 1030 1040 1050 1060 pF1KA1 QAHAKAKLVRLNEELAAKKREIQDLSKTVERLQKDRRMMLSNQNSKGREEMSAKRAKKDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QAHAKAKLVRLNEELAAKKREIQDLSKTVERLQKDRRMMLSNQNSKGREEMSAKRAKKDV 700 710 720 730 740 750 1070 1080 1090 1100 1110 1120 pF1KA1 LHSSKGNANSFPGTLDSKLYQPHTFTDSHVSEVLQENYRLKNELEGLISEKNELKMKSEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LHSSKGNANSFPGTLDSKLYQPHTFTDSHVSEVLQENYRLKNELEGLISEKNELKMKSEA 760 770 780 790 800 810 1130 1140 1150 1160 1170 1180 pF1KA1 VMNQFENSMRRVKEDTAAHIASLKASHQREIEKLLCQNAVENSSSKVAELNRKIATQEVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VMNQFENSMRRVKEDTAAHIASLKASHQREIEKLLCQNAVENSSSKVAELNRKIATQEVL 820 830 840 850 860 870 1190 1200 1210 1220 1230 1240 pF1KA1 IRHFQSQVNELQSKQESLVVSEVREEILQKEITKLLEELREAKENHTPEMKHFVGLEKKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IRHFQSQVNELQSKQESLVVSEVREEILQKEITKLLEELREAKENHTPEMKHFVGLEKKI 880 890 900 910 920 930 1250 1260 1270 1280 1290 1300 pF1KA1 KQMEMRHAQREQELQQIIQQTHQVVETEQNKEVEKWKRLAQLKNRELEKFRTELDSILDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KQMEMRHAQREQELQQIIQQTHQVVETEQNKEVEKWKRLAQLKNRELEKFRTELDSILDV 940 950 960 970 980 990 1310 1320 pF1KA1 LRELHRQGVVVPVAFADEMNAPEY :::::::::::::::::::::::: XP_011 LRELHRQGVVVPVAFADEMNAPEY 1000 1010 >>XP_005248735 (OMIM: 610201) PREDICTED: centrosomal pro (760 aa) initn: 4334 init1: 4334 opt: 4334 Z-score: 1736.0 bits: 332.7 E(85289): 5.9e-90 Smith-Waterman score: 4334; 99.9% identity (99.9% similar) in 683 aa overlap (1-683:77-759) 10 20 30 pF1KA1 MEIEEESAEKIQFLKSSGTSLLSTDSLETN :::::::::::::::::::::::::::::: XP_005 WWITEDDFKDDGLLGTNVSYLKTKKTSQPVMEIEEESAEKIQFLKSSGTSLLSTDSLETN 50 60 70 80 90 100 40 50 60 70 80 90 pF1KA1 ELVVSELNHSSLGVGLDTLEEQEEKEQFFARLEKGLTSSIDYSRLNKELDSNDSTHFKAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ELVVSELNHSSLGVGLDTLEEQEEKEQFFARLEKGLTSSIDYSRLNKELDSNDSTHFKAL 110 120 130 140 150 160 100 110 120 130 140 150 pF1KA1 HINQANAELTDDEHENESKHEELAENYSDDFEDEYVGAPLTTKDEEMPSKENSKSEKISV : :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HSNQANAELTDDEHENESKHEELAENYSDDFEDEYVGAPLTTKDEEMPSKENSKSEKISV 170 180 190 200 210 220 160 170 180 190 200 210 pF1KA1 PKQEEEKTGMLANVVLLDSLDSVAEVNLDEQDKITPKPRCLPEMTENEMTGTGVSYGQSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PKQEEEKTGMLANVVLLDSLDSVAEVNLDEQDKITPKPRCLPEMTENEMTGTGVSYGQSS 230 240 250 260 270 280 220 230 240 250 260 270 pF1KA1 SDVEALHQAYCHIAHSLGDEDKQKIESNTVEDIKSSVKGHPQENEENSKNISTMESDLPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SDVEALHQAYCHIAHSLGDEDKQKIESNTVEDIKSSVKGHPQENEENSKNISTMESDLPT 290 300 310 320 330 340 280 290 300 310 320 330 pF1KA1 VEELMKPIRIDSFGISGFDLQPVSSEKVAERKETEFFSSLPLKMNPNILSQDSQHVNLFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VEELMKPIRIDSFGISGFDLQPVSSEKVAERKETEFFSSLPLKMNPNILSQDSQHVNLFF 350 360 370 380 390 400 340 350 360 370 380 390 pF1KA1 DKNDENVILQKTTNESMENSCPQVTEVTATEEHVDKMYLNILRKKITVNSSSLSQDDKIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DKNDENVILQKTTNESMENSCPQVTEVTATEEHVDKMYLNILRKKITVNSSSLSQDDKIN 410 420 430 440 450 460 400 410 420 430 440 450 pF1KA1 KTYRSQLSSEEEGAVMGKQVPYKKARSAPPLLKRKPQSGLYASVRSSGYGKPSSPLKMFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KTYRSQLSSEEEGAVMGKQVPYKKARSAPPLLKRKPQSGLYASVRSSGYGKPSSPLKMFS 470 480 490 500 510 520 460 470 480 490 500 510 pF1KA1 TLEKKTSEDIIKSKNLRSISTSNQPRKKEILSGTKLIKPAALDKPAHKTESCLSTRKKSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TLEKKTSEDIIKSKNLRSISTSNQPRKKEILSGTKLIKPAALDKPAHKTESCLSTRKKSE 530 540 550 560 570 580 520 530 540 550 560 570 pF1KA1 NPTETDSCIQFQTDSLGYCGENKEKKLLMFKRVQEAEDKWRGAQALIEQIKATFSEKEKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NPTETDSCIQFQTDSLGYCGENKEKKLLMFKRVQEAEDKWRGAQALIEQIKATFSEKEKE 590 600 610 620 630 640 580 590 600 610 620 630 pF1KA1 LENKLEELKKQQEKELFKLNQDNYILQAKLSSFEETNKKQRWLHFGEAADPVTGEKLKQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LENKLEELKKQQEKELFKLNQDNYILQAKLSSFEETNKKQRWLHFGEAADPVTGEKLKQI 650 660 670 680 690 700 640 650 660 670 680 690 pF1KA1 QKEIQEQETLLQGYQQENERLYNQVKDLQEQNKKNEERMFKENQSLFSEVASLKEQMHKS ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QKEIQEQETLLQGYQQENERLYNQVKDLQEQNKKNEERMFKENQSLFSEVASLN 710 720 730 740 750 760 700 710 720 730 740 750 pF1KA1 RFLSQVVEDSEPTRNQNFTDLLAELRMAQKEKDSLLEDIKRLKQDKQALEVDFEKMKKER >>XP_011533896 (OMIM: 610201) PREDICTED: centrosomal pro (761 aa) initn: 4334 init1: 4334 opt: 4334 Z-score: 1736.0 bits: 332.7 E(85289): 5.9e-90 Smith-Waterman score: 4334; 99.9% identity (99.9% similar) in 683 aa overlap (1-683:77-759) 10 20 30 pF1KA1 MEIEEESAEKIQFLKSSGTSLLSTDSLETN :::::::::::::::::::::::::::::: XP_011 WWITEDDFKDDGLLGTNVSYLKTKKTSQPVMEIEEESAEKIQFLKSSGTSLLSTDSLETN 50 60 70 80 90 100 40 50 60 70 80 90 pF1KA1 ELVVSELNHSSLGVGLDTLEEQEEKEQFFARLEKGLTSSIDYSRLNKELDSNDSTHFKAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELVVSELNHSSLGVGLDTLEEQEEKEQFFARLEKGLTSSIDYSRLNKELDSNDSTHFKAL 110 120 130 140 150 160 100 110 120 130 140 150 pF1KA1 HINQANAELTDDEHENESKHEELAENYSDDFEDEYVGAPLTTKDEEMPSKENSKSEKISV : :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HSNQANAELTDDEHENESKHEELAENYSDDFEDEYVGAPLTTKDEEMPSKENSKSEKISV 170 180 190 200 210 220 160 170 180 190 200 210 pF1KA1 PKQEEEKTGMLANVVLLDSLDSVAEVNLDEQDKITPKPRCLPEMTENEMTGTGVSYGQSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PKQEEEKTGMLANVVLLDSLDSVAEVNLDEQDKITPKPRCLPEMTENEMTGTGVSYGQSS 230 240 250 260 270 280 220 230 240 250 260 270 pF1KA1 SDVEALHQAYCHIAHSLGDEDKQKIESNTVEDIKSSVKGHPQENEENSKNISTMESDLPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SDVEALHQAYCHIAHSLGDEDKQKIESNTVEDIKSSVKGHPQENEENSKNISTMESDLPT 290 300 310 320 330 340 280 290 300 310 320 330 pF1KA1 VEELMKPIRIDSFGISGFDLQPVSSEKVAERKETEFFSSLPLKMNPNILSQDSQHVNLFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VEELMKPIRIDSFGISGFDLQPVSSEKVAERKETEFFSSLPLKMNPNILSQDSQHVNLFF 350 360 370 380 390 400 340 350 360 370 380 390 pF1KA1 DKNDENVILQKTTNESMENSCPQVTEVTATEEHVDKMYLNILRKKITVNSSSLSQDDKIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DKNDENVILQKTTNESMENSCPQVTEVTATEEHVDKMYLNILRKKITVNSSSLSQDDKIN 410 420 430 440 450 460 400 410 420 430 440 450 pF1KA1 KTYRSQLSSEEEGAVMGKQVPYKKARSAPPLLKRKPQSGLYASVRSSGYGKPSSPLKMFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KTYRSQLSSEEEGAVMGKQVPYKKARSAPPLLKRKPQSGLYASVRSSGYGKPSSPLKMFS 470 480 490 500 510 520 460 470 480 490 500 510 pF1KA1 TLEKKTSEDIIKSKNLRSISTSNQPRKKEILSGTKLIKPAALDKPAHKTESCLSTRKKSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLEKKTSEDIIKSKNLRSISTSNQPRKKEILSGTKLIKPAALDKPAHKTESCLSTRKKSE 530 540 550 560 570 580 520 530 540 550 560 570 pF1KA1 NPTETDSCIQFQTDSLGYCGENKEKKLLMFKRVQEAEDKWRGAQALIEQIKATFSEKEKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NPTETDSCIQFQTDSLGYCGENKEKKLLMFKRVQEAEDKWRGAQALIEQIKATFSEKEKE 590 600 610 620 630 640 580 590 600 610 620 630 pF1KA1 LENKLEELKKQQEKELFKLNQDNYILQAKLSSFEETNKKQRWLHFGEAADPVTGEKLKQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LENKLEELKKQQEKELFKLNQDNYILQAKLSSFEETNKKQRWLHFGEAADPVTGEKLKQI 650 660 670 680 690 700 640 650 660 670 680 690 pF1KA1 QKEIQEQETLLQGYQQENERLYNQVKDLQEQNKKNEERMFKENQSLFSEVASLKEQMHKS ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QKEIQEQETLLQGYQQENERLYNQVKDLQEQNKKNEERMFKENQSLFSEVASLNS 710 720 730 740 750 760 700 710 720 730 740 750 pF1KA1 RFLSQVVEDSEPTRNQNFTDLLAELRMAQKEKDSLLEDIKRLKQDKQALEVDFEKMKKER >>XP_016861684 (OMIM: 602500) PREDICTED: golgin subfamil (3016 aa) initn: 131 init1: 90 opt: 381 Z-score: 173.2 bits: 45.6 E(85289): 0.0065 Smith-Waterman score: 452; 21.5% identity (54.9% similar) in 1212 aa overlap (142-1308:753-1858) 120 130 140 150 160 170 pF1KA1 ELAENYSDDFEDEYVGAPLTTKDEEMPSKENSKSEKISVPKQEEEKTGMLANVVLLDSLD : : : . ::: ::: : : . XP_016 QISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEE----LAN--LKD--E 730 740 750 760 770 180 190 200 210 220 pF1KA1 SVAEVNLDEQDKI-TPKPRCLPEMTENEMTGTG----VSYGQSSSDVEALHQAYCHIAHS : :. :.: .. . . . :..:. .:. . :. :. :. : :: .. XP_016 SKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQ---HIRKD 780 790 800 810 820 830 230 240 250 260 270 280 pF1KA1 LGDEDKQKIESNTVEDIKSSVKGHPQENEENSKNISTMESDLPTVEELMKPIRIDSFGIS : :.: : :.... :: : ......:. ..... . ... . .. : XP_016 L--EEKLAAE----EQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDAS 840 850 860 870 880 290 300 310 320 330 340 pF1KA1 GFDLQPVSSEKVAERKETEFFSSLPLKMNPNILSQDSQHVNLFFDKNDENVILQKTTNES : .:: ::: .: : . . . . .. : ..:. :. ::: .:. XP_016 DGD-------SVALVKETVVISP-PCTGSSEHWKPELEEKILALEKEKEQ--LQKKLQEA 890 900 910 920 930 350 360 370 380 390 400 pF1KA1 MENSCPQVTEVTATEEHVDKMYLNILRKKITVNSSSLSQDDKINKTYRSQLSSEEEGAVM . . . .. :.: ::... .: : :. .. . .:. . XP_016 LTSRKAILKKAQEKERH--------LREELK------QQKDDYNRLQEQFDEQSKENENI 940 950 960 970 980 410 420 430 440 450 460 pF1KA1 GKQVPYKKARSAPPLLKRKPQSGLYASVRSSGYGKPSSPLKMFSTLEKKTSEDIIKSKNL : :. . . . . :.. : :. :. .:.. :.. .. ...: :: XP_016 GDQLRQLQIQVRESIDGKLPSTDQQESCSST----PGLEEPLFKATEQHHTQPVLES-NL 990 1000 1010 1020 1030 470 480 490 500 510 520 pF1KA1 RSISTSNQPRKKEILSGTKL--IKPAALDKPAHKTESCLS-TRKKSENPTETDSCIQFQT :.. . . .::.. :: . :.:.: :. . :: ... .:.: XP_016 CPDWPSHSEDASALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQ- 1040 1050 1060 1070 1080 1090 530 540 550 560 570 580 pF1KA1 DSLGYCGENKEKKLLMFKRV-QEAEDKWRGAQALIE--QIKATFSEKEKELENKLEELKK .... : . :. .: : .::: . .. : .: :.. . :. .::. ::.::.: XP_016 EQINKQGLEIES----LKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRELQPKLDELQK 1100 1110 1120 1130 1140 1150 590 600 610 620 630 pF1KA1 ---QQEKELFKLNQDNYILQAKLSSFEETNKKQ----RWLHFG-EAADPVTGEKLKQIQK ..:... :. . .: :.... .: . :: : :..::.: XP_016 LISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQV 1160 1170 1180 1190 1200 1210 640 650 660 670 680 690 pF1KA1 EIQEQETLLQGYQQENERLYNQVKDLQEQNKKNEERMFKENQSLFSEVASLKEQMHK-SR :. :.. . .:. : .:.. . .... .:::.:: :.. . ... .. XP_016 ELCEMKQKPEEIGEES-RAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTK 1220 1230 1240 1250 1260 1270 700 710 720 730 740 750 pF1KA1 FLSQVVEDSEPTRNQNFTDLLAELRMAQKEKDSLLEDIKRLKQDKQALEVDFEKMKKERD :..: :.. ..:.. .:..: . :.:.:.:. .. : ..:.: . :..: . XP_016 SLADV-ESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALE 1280 1290 1300 1310 1320 760 770 780 790 800 pF1KA1 Q-AKDQIAYVTG-EKLYEIKILEETHKQEISR-LQKRLQWYAENQELLDKDALRLREANE ..:. : :.: :: : :. :: . :::. . .. : ....: :.... : XP_016 GLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVE 1330 1340 1350 1360 1370 1380 810 820 830 840 850 860 pF1KA1 EIEKLKLEIE-KLKAESGNPSIRQKIRLKDKAADAKKIQDLERQVKEMEGILKRRYPNSL ... : :. ::.. .: : :..:. :....::. . :.. .: XP_016 AVRQEKQELYGKLRSTEAN-----------KKETEKQLQEAEQEMEEMKEKM-RKFAKSK 1390 1400 1410 1420 1430 870 880 890 900 910 920 pF1KA1 PALILAASAAGDTVDKNTVEFMEKRIKKLEADLEGKDEDAKKSLRTMEQQFQKMKIQYEQ :: .:.. .:.:... . ::. ..:. .. .:: . : XP_016 QQKILE---------------LEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELE- 1440 1450 1460 1470 1480 930 940 950 960 970 980 pF1KA1 RLEQQEQLLACKLNQHDSPRIKALEKELDDIKEAHQITVRNLEAEIDVLKHQNAELDVKK :.... . :. :... : . .: .:..:.: ::: : .: :. : : :. XP_016 RVKMEYETLSKKFQSLMSEK-DSLSEEVQDLK--HQI-------EGNVSKQANLEATEKH 1490 1500 1510 1520 1530 990 1000 1010 1020 pF1KA1 NDKDD---EDFQSIEFQVEQAHAKAKLVR--LNEELAAKKR-------------EIQDLS ... . : ::: ..:. . . .: .: . . : ::.. XP_016 DNQTNVTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYL 1540 1550 1560 1570 1580 1590 1030 1040 1050 1060 1070 1080 pF1KA1 KTVERLQKDRRMMLSNQNSKGREEMSAKRAKKDVLHSSKGNANSFPGTLDSKLYQPHTFT . ...: :.: : ....:..: .. . .:..: :. .. .. :. .. . .. XP_016 QQIDQL-KERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTK-MNLL 1600 1610 1620 1630 1640 1090 1100 1110 1120 1130 1140 pF1KA1 DSHVSEVLQENYRLKNELEGLISEKNELKMKSEAVMNQFENSMRRVKED-TAAHIAS-LK .....: :.. .::. : ::..:. . . ....:. .: : :.: . : XP_016 NQQIQEELSRVTKLKETAE---EEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELL 1650 1660 1670 1680 1690 1700 1150 1160 1170 1180 1190 1200 pF1KA1 ASHQREIEKLLCQNAVENSSSKVAELNRKIATQEVLIRHFQSQVNELQSKQ-ESLVVSEV :......: : . .:. ...... . :. .. :: . ....:. : : :.. XP_016 ESEMKNLKK--CVSELEEEKQQLVKEKTKVESE---IR--KEYLEKIQGAQKEPGNKSHA 1710 1720 1730 1740 1750 1210 1220 1230 1240 1250 1260 pF1KA1 REEILQKEITKLLEELREAKENHTPEMKHFVGLEKKIKQMEMRHAQREQELQQIIQQTHQ .: ::. . . .:... ... .... .::. .: .:. ... ...:. .. : XP_016 KE--LQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQ 1760 1770 1780 1790 1800 1810 1270 1280 1290 1300 1310 1320 pF1KA1 VVETEQNKEVEKWKRLAQLKNRELEKFRTELDSILDVLRELHRQGVVVPVAFADEMNAPE .:: ... ..: . . : . . : :. :. : . .::. XP_016 AVEHRKKAQAELASFKVLLDDTQSEAARVLADN-LKLKKELQSNKESVKSQMKQKDEDLE 1820 1830 1840 1850 1860 1870 pF1KA1 Y XP_016 RRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTV 1880 1890 1900 1910 1920 1930 1327 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 01:16:59 2016 done: Fri Nov 4 01:17:01 2016 Total Scan time: 16.760 Total Display time: 0.720 Function used was FASTA [36.3.4 Apr, 2011]