FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1018, 1017 aa 1>>>pF1KA1018 1017 - 1017 aa - 1017 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.6414+/-0.000935; mu= 14.8780+/- 0.056 mean_var=83.3549+/-16.626, 0's: 0 Z-trim(106.1): 26 B-trim: 0 in 0/51 Lambda= 0.140478 statistics sampled from 8790 (8798) to 8790 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.637), E-opt: 0.2 (0.27), width: 16 Scan time: 4.650 The best scores are: opt bits E(32554) CCDS32186.1 FAN1 gene_id:22909|Hs108|chr15 (1017) 6776 1383.6 0 CCDS58344.1 FAN1 gene_id:22909|Hs108|chr15 ( 533) 3422 703.8 2.4e-202 >>CCDS32186.1 FAN1 gene_id:22909|Hs108|chr15 (1017 aa) initn: 6776 init1: 6776 opt: 6776 Z-score: 7415.3 bits: 1383.6 E(32554): 0 Smith-Waterman score: 6776; 99.9% identity (100.0% similar) in 1017 aa overlap (1-1017:1-1017) 10 20 30 40 50 60 pF1KA1 MMSEGKPPDKKRPRRSLSISKNKKKASNSIISCFNNAPPAKLACPVCSKMVPRYDLNRHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 MMSEGKPPDKKRPRRSLSISKNKKKASNSIISCFNNAPPAKLACPVCSKMVPRYDLNRHL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 DEMCANNDFVQVDPGQVGLINSNVSMVDLTSVTLEDVTPKKSPPPKTNLTPGQSDSAKRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 DEMCANNDFVQVDPGQVGLINSNVSMVDLTSVTLEDVTPKKSPPPKTNLTPGQSDSAKRE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 VKQKISPYFKSNDVVCKNQDELRNRSVKVICLGSLASKLSRKYVKAKKSIDKDEEFAGSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 VKQKISPYFKSNDVVCKNQDELRNRSVKVICLGSLASKLSRKYVKAKKSIDKDEEFAGSS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 PQSSKSTVVKSLIDNSSEIEDEDQILENSSQKENVFKCDSLKEECIPEHMVRGSKIMEAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 PQSSKSTVVKSLIDNSSEIEDEDQILENSSQKENVFKCDSLKEECIPEHMVRGSKIMEAE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 SQKATRECEKSALTPGFSDNAIMLFSPDFTLRNTLKSTSEDSLVKQECIKEVVEKREACH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 SQKATRECEKSALTPGFSDNAIMLFSPDFTLRNTLKSTSEDSLVKQECIKEVVEKREACH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 CEEVKMTVASEAKIQLSDSEAKSHSSADDASAWSNIQEAPLQDDSCLNNDIPHSIPLEQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 CEEVKMTVASEAKIQLSDSEAKSHSSADDASAWSNIQEAPLQDDSCLNNDIPHSIPLEQG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 SSCNGPGQTTGHPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 SSCNGPGQTTGHPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYVR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 LFQRKLSWIKMTKLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 LFQRKLSWIKMTKLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKSL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 AKTFHLANPNGQKQQLVDAFLKLAKQRSVCTWGKNKPGIGAVILKRAKALAGQSVRICKG ::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 AKTFHLVNPNGQKQQLVDAFLKLAKQRSVCTWGKNKPGIGAVILKRAKALAGQSVRICKG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 PRAVFSRILLLFSLTDSMEDEDAACGGQGQLSTVLLVNLGRMEFPSYTINRKTHIFQDRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 PRAVFSRILLLFSLTDSMEDEDAACGGQGQLSTVLLVNLGRMEFPSYTINRKTHIFQDRD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 DLIRYAAATHMLSDISSAMANGNWEEAKELAQCAKRDWNRLKNHPSLRCHEDLPLFLRCF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 DLIRYAAATHMLSDISSAMANGNWEEAKELAQCAKRDWNRLKNHPSLRCHEDLPLFLRCF 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 TVGWIYTRILSRFVEILQRLHMYEEAVRELESLLSQRIYCPDSRGRWWDRLALNLHQHLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 TVGWIYTRILSRFVEILQRLHMYEEAVRELESLLSQRIYCPDSRGRWWDRLALNLHQHLK 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 RLEPTIKCITEGLADPEVRTGHRLSLYQRAVRLRESPSCKKFKHLFQQLPEMAVQDVKHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 RLEPTIKCITEGLADPEVRTGHRLSLYQRAVRLRESPSCKKFKHLFQQLPEMAVQDVKHV 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 TITGRLCPQRGMCKSVFVMEAGEAADPTTVLCSVEELALAHYRRSGFDQGIHGEGSTFST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 TITGRLCPQRGMCKSVFVMEAGEAADPTTVLCSVEELALAHYRRSGFDQGIHGEGSTFST 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 LYGLLLWDIIFMDGIPDVFRNACQAFPLDLCTDSFFTSRRPALEARLQLIHDAPEESLRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 LYGLLLWDIIFMDGIPDVFRNACQAFPLDLCTDSFFTSRRPALEARLQLIHDAPEESLRA 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 WVAATWHEQEGRVASLVSWDRFTSLQQAQDLVSCLGGPVLSGVCRHLAADFRHCRGGLPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 WVAATWHEQEGRVASLVSWDRFTSLQQAQDLVSCLGGPVLSGVCRHLAADFRHCRGGLPD 910 920 930 940 950 960 970 980 990 1000 1010 pF1KA1 LVVWNSQSRHFKLVEVKGPNDRLSHKQMIWLAELQKLGAEVEVCHVVAVGAKSQSLS ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 LVVWNSQSRHFKLVEVKGPNDRLSHKQMIWLAELQKLGAEVEVCHVVAVGAKSQSLS 970 980 990 1000 1010 >>CCDS58344.1 FAN1 gene_id:22909|Hs108|chr15 (533 aa) initn: 3422 init1: 3422 opt: 3422 Z-score: 3746.4 bits: 703.8 E(32554): 2.4e-202 Smith-Waterman score: 3422; 99.8% identity (100.0% similar) in 526 aa overlap (1-526:1-526) 10 20 30 40 50 60 pF1KA1 MMSEGKPPDKKRPRRSLSISKNKKKASNSIISCFNNAPPAKLACPVCSKMVPRYDLNRHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 MMSEGKPPDKKRPRRSLSISKNKKKASNSIISCFNNAPPAKLACPVCSKMVPRYDLNRHL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 DEMCANNDFVQVDPGQVGLINSNVSMVDLTSVTLEDVTPKKSPPPKTNLTPGQSDSAKRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 DEMCANNDFVQVDPGQVGLINSNVSMVDLTSVTLEDVTPKKSPPPKTNLTPGQSDSAKRE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 VKQKISPYFKSNDVVCKNQDELRNRSVKVICLGSLASKLSRKYVKAKKSIDKDEEFAGSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 VKQKISPYFKSNDVVCKNQDELRNRSVKVICLGSLASKLSRKYVKAKKSIDKDEEFAGSS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 PQSSKSTVVKSLIDNSSEIEDEDQILENSSQKENVFKCDSLKEECIPEHMVRGSKIMEAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 PQSSKSTVVKSLIDNSSEIEDEDQILENSSQKENVFKCDSLKEECIPEHMVRGSKIMEAE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 SQKATRECEKSALTPGFSDNAIMLFSPDFTLRNTLKSTSEDSLVKQECIKEVVEKREACH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 SQKATRECEKSALTPGFSDNAIMLFSPDFTLRNTLKSTSEDSLVKQECIKEVVEKREACH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 CEEVKMTVASEAKIQLSDSEAKSHSSADDASAWSNIQEAPLQDDSCLNNDIPHSIPLEQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 CEEVKMTVASEAKIQLSDSEAKSHSSADDASAWSNIQEAPLQDDSCLNNDIPHSIPLEQG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 SSCNGPGQTTGHPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 SSCNGPGQTTGHPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYVR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 LFQRKLSWIKMTKLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 LFQRKLSWIKMTKLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKSL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 AKTFHLANPNGQKQQLVDAFLKLAKQRSVCTWGKNKPGIGAVILKRAKALAGQSVRICKG ::::::.::::::::::::::::::::::::::::::::::::::: CCDS58 AKTFHLVNPNGQKQQLVDAFLKLAKQRSVCTWGKNKPGIGAVILKRFCWLLLQ 490 500 510 520 530 550 560 570 580 590 600 pF1KA1 PRAVFSRILLLFSLTDSMEDEDAACGGQGQLSTVLLVNLGRMEFPSYTINRKTHIFQDRD 1017 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 10:40:34 2016 done: Thu Nov 3 10:40:35 2016 Total Scan time: 4.650 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]