FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1018, 1017 aa 1>>>pF1KA1018 1017 - 1017 aa - 1017 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.2190+/-0.000396; mu= 17.6969+/- 0.025 mean_var=94.2389+/-19.305, 0's: 0 Z-trim(113.2): 31 B-trim: 143 in 1/53 Lambda= 0.132117 statistics sampled from 22430 (22460) to 22430 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.623), E-opt: 0.2 (0.263), width: 16 Scan time: 14.370 The best scores are: opt bits E(85289) XP_005254289 (OMIM: 613534,614817) PREDICTED: fanc (1017) 6776 1302.7 0 XP_005254291 (OMIM: 613534,614817) PREDICTED: fanc (1017) 6776 1302.7 0 XP_005254292 (OMIM: 613534,614817) PREDICTED: fanc (1017) 6776 1302.7 0 NP_055782 (OMIM: 613534,614817) fanconi-associated (1017) 6776 1302.7 0 XP_011519673 (OMIM: 613534,614817) PREDICTED: fanc ( 622) 4077 788.1 0 XP_011519672 (OMIM: 613534,614817) PREDICTED: fanc ( 623) 4072 787.2 0 XP_011519674 (OMIM: 613534,614817) PREDICTED: fanc ( 609) 3930 760.1 8.1e-219 NP_001139567 (OMIM: 613534,614817) fanconi-associa ( 533) 3422 663.2 1e-189 NP_001139566 (OMIM: 613534,614817) fanconi-associa ( 533) 3422 663.2 1e-189 NP_001139568 (OMIM: 613534,614817) fanconi-associa ( 533) 3422 663.2 1e-189 XP_016877502 (OMIM: 613534,614817) PREDICTED: fanc ( 460) 3161 613.5 8.6e-175 XP_016877501 (OMIM: 613534,614817) PREDICTED: fanc ( 460) 3161 613.5 8.6e-175 >>XP_005254289 (OMIM: 613534,614817) PREDICTED: fanconi- (1017 aa) initn: 6776 init1: 6776 opt: 6776 Z-score: 6977.9 bits: 1302.7 E(85289): 0 Smith-Waterman score: 6776; 99.9% identity (100.0% similar) in 1017 aa overlap (1-1017:1-1017) 10 20 30 40 50 60 pF1KA1 MMSEGKPPDKKRPRRSLSISKNKKKASNSIISCFNNAPPAKLACPVCSKMVPRYDLNRHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MMSEGKPPDKKRPRRSLSISKNKKKASNSIISCFNNAPPAKLACPVCSKMVPRYDLNRHL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 DEMCANNDFVQVDPGQVGLINSNVSMVDLTSVTLEDVTPKKSPPPKTNLTPGQSDSAKRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DEMCANNDFVQVDPGQVGLINSNVSMVDLTSVTLEDVTPKKSPPPKTNLTPGQSDSAKRE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 VKQKISPYFKSNDVVCKNQDELRNRSVKVICLGSLASKLSRKYVKAKKSIDKDEEFAGSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VKQKISPYFKSNDVVCKNQDELRNRSVKVICLGSLASKLSRKYVKAKKSIDKDEEFAGSS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 PQSSKSTVVKSLIDNSSEIEDEDQILENSSQKENVFKCDSLKEECIPEHMVRGSKIMEAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQSSKSTVVKSLIDNSSEIEDEDQILENSSQKENVFKCDSLKEECIPEHMVRGSKIMEAE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 SQKATRECEKSALTPGFSDNAIMLFSPDFTLRNTLKSTSEDSLVKQECIKEVVEKREACH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SQKATRECEKSALTPGFSDNAIMLFSPDFTLRNTLKSTSEDSLVKQECIKEVVEKREACH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 CEEVKMTVASEAKIQLSDSEAKSHSSADDASAWSNIQEAPLQDDSCLNNDIPHSIPLEQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CEEVKMTVASEAKIQLSDSEAKSHSSADDASAWSNIQEAPLQDDSCLNNDIPHSIPLEQG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 SSCNGPGQTTGHPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSCNGPGQTTGHPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYVR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 LFQRKLSWIKMTKLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LFQRKLSWIKMTKLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKSL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 AKTFHLANPNGQKQQLVDAFLKLAKQRSVCTWGKNKPGIGAVILKRAKALAGQSVRICKG ::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AKTFHLVNPNGQKQQLVDAFLKLAKQRSVCTWGKNKPGIGAVILKRAKALAGQSVRICKG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 PRAVFSRILLLFSLTDSMEDEDAACGGQGQLSTVLLVNLGRMEFPSYTINRKTHIFQDRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PRAVFSRILLLFSLTDSMEDEDAACGGQGQLSTVLLVNLGRMEFPSYTINRKTHIFQDRD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 DLIRYAAATHMLSDISSAMANGNWEEAKELAQCAKRDWNRLKNHPSLRCHEDLPLFLRCF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DLIRYAAATHMLSDISSAMANGNWEEAKELAQCAKRDWNRLKNHPSLRCHEDLPLFLRCF 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 TVGWIYTRILSRFVEILQRLHMYEEAVRELESLLSQRIYCPDSRGRWWDRLALNLHQHLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TVGWIYTRILSRFVEILQRLHMYEEAVRELESLLSQRIYCPDSRGRWWDRLALNLHQHLK 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 RLEPTIKCITEGLADPEVRTGHRLSLYQRAVRLRESPSCKKFKHLFQQLPEMAVQDVKHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RLEPTIKCITEGLADPEVRTGHRLSLYQRAVRLRESPSCKKFKHLFQQLPEMAVQDVKHV 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 TITGRLCPQRGMCKSVFVMEAGEAADPTTVLCSVEELALAHYRRSGFDQGIHGEGSTFST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TITGRLCPQRGMCKSVFVMEAGEAADPTTVLCSVEELALAHYRRSGFDQGIHGEGSTFST 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 LYGLLLWDIIFMDGIPDVFRNACQAFPLDLCTDSFFTSRRPALEARLQLIHDAPEESLRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LYGLLLWDIIFMDGIPDVFRNACQAFPLDLCTDSFFTSRRPALEARLQLIHDAPEESLRA 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 WVAATWHEQEGRVASLVSWDRFTSLQQAQDLVSCLGGPVLSGVCRHLAADFRHCRGGLPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WVAATWHEQEGRVASLVSWDRFTSLQQAQDLVSCLGGPVLSGVCRHLAADFRHCRGGLPD 910 920 930 940 950 960 970 980 990 1000 1010 pF1KA1 LVVWNSQSRHFKLVEVKGPNDRLSHKQMIWLAELQKLGAEVEVCHVVAVGAKSQSLS ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LVVWNSQSRHFKLVEVKGPNDRLSHKQMIWLAELQKLGAEVEVCHVVAVGAKSQSLS 970 980 990 1000 1010 >>XP_005254291 (OMIM: 613534,614817) PREDICTED: fanconi- (1017 aa) initn: 6776 init1: 6776 opt: 6776 Z-score: 6977.9 bits: 1302.7 E(85289): 0 Smith-Waterman score: 6776; 99.9% identity (100.0% similar) in 1017 aa overlap (1-1017:1-1017) 10 20 30 40 50 60 pF1KA1 MMSEGKPPDKKRPRRSLSISKNKKKASNSIISCFNNAPPAKLACPVCSKMVPRYDLNRHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MMSEGKPPDKKRPRRSLSISKNKKKASNSIISCFNNAPPAKLACPVCSKMVPRYDLNRHL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 DEMCANNDFVQVDPGQVGLINSNVSMVDLTSVTLEDVTPKKSPPPKTNLTPGQSDSAKRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DEMCANNDFVQVDPGQVGLINSNVSMVDLTSVTLEDVTPKKSPPPKTNLTPGQSDSAKRE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 VKQKISPYFKSNDVVCKNQDELRNRSVKVICLGSLASKLSRKYVKAKKSIDKDEEFAGSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VKQKISPYFKSNDVVCKNQDELRNRSVKVICLGSLASKLSRKYVKAKKSIDKDEEFAGSS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 PQSSKSTVVKSLIDNSSEIEDEDQILENSSQKENVFKCDSLKEECIPEHMVRGSKIMEAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQSSKSTVVKSLIDNSSEIEDEDQILENSSQKENVFKCDSLKEECIPEHMVRGSKIMEAE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 SQKATRECEKSALTPGFSDNAIMLFSPDFTLRNTLKSTSEDSLVKQECIKEVVEKREACH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SQKATRECEKSALTPGFSDNAIMLFSPDFTLRNTLKSTSEDSLVKQECIKEVVEKREACH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 CEEVKMTVASEAKIQLSDSEAKSHSSADDASAWSNIQEAPLQDDSCLNNDIPHSIPLEQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CEEVKMTVASEAKIQLSDSEAKSHSSADDASAWSNIQEAPLQDDSCLNNDIPHSIPLEQG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 SSCNGPGQTTGHPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSCNGPGQTTGHPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYVR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 LFQRKLSWIKMTKLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LFQRKLSWIKMTKLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKSL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 AKTFHLANPNGQKQQLVDAFLKLAKQRSVCTWGKNKPGIGAVILKRAKALAGQSVRICKG ::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AKTFHLVNPNGQKQQLVDAFLKLAKQRSVCTWGKNKPGIGAVILKRAKALAGQSVRICKG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 PRAVFSRILLLFSLTDSMEDEDAACGGQGQLSTVLLVNLGRMEFPSYTINRKTHIFQDRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PRAVFSRILLLFSLTDSMEDEDAACGGQGQLSTVLLVNLGRMEFPSYTINRKTHIFQDRD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 DLIRYAAATHMLSDISSAMANGNWEEAKELAQCAKRDWNRLKNHPSLRCHEDLPLFLRCF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DLIRYAAATHMLSDISSAMANGNWEEAKELAQCAKRDWNRLKNHPSLRCHEDLPLFLRCF 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 TVGWIYTRILSRFVEILQRLHMYEEAVRELESLLSQRIYCPDSRGRWWDRLALNLHQHLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TVGWIYTRILSRFVEILQRLHMYEEAVRELESLLSQRIYCPDSRGRWWDRLALNLHQHLK 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 RLEPTIKCITEGLADPEVRTGHRLSLYQRAVRLRESPSCKKFKHLFQQLPEMAVQDVKHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RLEPTIKCITEGLADPEVRTGHRLSLYQRAVRLRESPSCKKFKHLFQQLPEMAVQDVKHV 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 TITGRLCPQRGMCKSVFVMEAGEAADPTTVLCSVEELALAHYRRSGFDQGIHGEGSTFST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TITGRLCPQRGMCKSVFVMEAGEAADPTTVLCSVEELALAHYRRSGFDQGIHGEGSTFST 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 LYGLLLWDIIFMDGIPDVFRNACQAFPLDLCTDSFFTSRRPALEARLQLIHDAPEESLRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LYGLLLWDIIFMDGIPDVFRNACQAFPLDLCTDSFFTSRRPALEARLQLIHDAPEESLRA 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 WVAATWHEQEGRVASLVSWDRFTSLQQAQDLVSCLGGPVLSGVCRHLAADFRHCRGGLPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WVAATWHEQEGRVASLVSWDRFTSLQQAQDLVSCLGGPVLSGVCRHLAADFRHCRGGLPD 910 920 930 940 950 960 970 980 990 1000 1010 pF1KA1 LVVWNSQSRHFKLVEVKGPNDRLSHKQMIWLAELQKLGAEVEVCHVVAVGAKSQSLS ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LVVWNSQSRHFKLVEVKGPNDRLSHKQMIWLAELQKLGAEVEVCHVVAVGAKSQSLS 970 980 990 1000 1010 >>XP_005254292 (OMIM: 613534,614817) PREDICTED: fanconi- (1017 aa) initn: 6776 init1: 6776 opt: 6776 Z-score: 6977.9 bits: 1302.7 E(85289): 0 Smith-Waterman score: 6776; 99.9% identity (100.0% similar) in 1017 aa overlap (1-1017:1-1017) 10 20 30 40 50 60 pF1KA1 MMSEGKPPDKKRPRRSLSISKNKKKASNSIISCFNNAPPAKLACPVCSKMVPRYDLNRHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MMSEGKPPDKKRPRRSLSISKNKKKASNSIISCFNNAPPAKLACPVCSKMVPRYDLNRHL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 DEMCANNDFVQVDPGQVGLINSNVSMVDLTSVTLEDVTPKKSPPPKTNLTPGQSDSAKRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DEMCANNDFVQVDPGQVGLINSNVSMVDLTSVTLEDVTPKKSPPPKTNLTPGQSDSAKRE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 VKQKISPYFKSNDVVCKNQDELRNRSVKVICLGSLASKLSRKYVKAKKSIDKDEEFAGSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VKQKISPYFKSNDVVCKNQDELRNRSVKVICLGSLASKLSRKYVKAKKSIDKDEEFAGSS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 PQSSKSTVVKSLIDNSSEIEDEDQILENSSQKENVFKCDSLKEECIPEHMVRGSKIMEAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQSSKSTVVKSLIDNSSEIEDEDQILENSSQKENVFKCDSLKEECIPEHMVRGSKIMEAE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 SQKATRECEKSALTPGFSDNAIMLFSPDFTLRNTLKSTSEDSLVKQECIKEVVEKREACH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SQKATRECEKSALTPGFSDNAIMLFSPDFTLRNTLKSTSEDSLVKQECIKEVVEKREACH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 CEEVKMTVASEAKIQLSDSEAKSHSSADDASAWSNIQEAPLQDDSCLNNDIPHSIPLEQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CEEVKMTVASEAKIQLSDSEAKSHSSADDASAWSNIQEAPLQDDSCLNNDIPHSIPLEQG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 SSCNGPGQTTGHPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSCNGPGQTTGHPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYVR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 LFQRKLSWIKMTKLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LFQRKLSWIKMTKLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKSL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 AKTFHLANPNGQKQQLVDAFLKLAKQRSVCTWGKNKPGIGAVILKRAKALAGQSVRICKG ::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AKTFHLVNPNGQKQQLVDAFLKLAKQRSVCTWGKNKPGIGAVILKRAKALAGQSVRICKG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 PRAVFSRILLLFSLTDSMEDEDAACGGQGQLSTVLLVNLGRMEFPSYTINRKTHIFQDRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PRAVFSRILLLFSLTDSMEDEDAACGGQGQLSTVLLVNLGRMEFPSYTINRKTHIFQDRD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 DLIRYAAATHMLSDISSAMANGNWEEAKELAQCAKRDWNRLKNHPSLRCHEDLPLFLRCF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DLIRYAAATHMLSDISSAMANGNWEEAKELAQCAKRDWNRLKNHPSLRCHEDLPLFLRCF 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 TVGWIYTRILSRFVEILQRLHMYEEAVRELESLLSQRIYCPDSRGRWWDRLALNLHQHLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TVGWIYTRILSRFVEILQRLHMYEEAVRELESLLSQRIYCPDSRGRWWDRLALNLHQHLK 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 RLEPTIKCITEGLADPEVRTGHRLSLYQRAVRLRESPSCKKFKHLFQQLPEMAVQDVKHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RLEPTIKCITEGLADPEVRTGHRLSLYQRAVRLRESPSCKKFKHLFQQLPEMAVQDVKHV 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 TITGRLCPQRGMCKSVFVMEAGEAADPTTVLCSVEELALAHYRRSGFDQGIHGEGSTFST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TITGRLCPQRGMCKSVFVMEAGEAADPTTVLCSVEELALAHYRRSGFDQGIHGEGSTFST 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 LYGLLLWDIIFMDGIPDVFRNACQAFPLDLCTDSFFTSRRPALEARLQLIHDAPEESLRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LYGLLLWDIIFMDGIPDVFRNACQAFPLDLCTDSFFTSRRPALEARLQLIHDAPEESLRA 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 WVAATWHEQEGRVASLVSWDRFTSLQQAQDLVSCLGGPVLSGVCRHLAADFRHCRGGLPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WVAATWHEQEGRVASLVSWDRFTSLQQAQDLVSCLGGPVLSGVCRHLAADFRHCRGGLPD 910 920 930 940 950 960 970 980 990 1000 1010 pF1KA1 LVVWNSQSRHFKLVEVKGPNDRLSHKQMIWLAELQKLGAEVEVCHVVAVGAKSQSLS ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LVVWNSQSRHFKLVEVKGPNDRLSHKQMIWLAELQKLGAEVEVCHVVAVGAKSQSLS 970 980 990 1000 1010 >>NP_055782 (OMIM: 613534,614817) fanconi-associated nuc (1017 aa) initn: 6776 init1: 6776 opt: 6776 Z-score: 6977.9 bits: 1302.7 E(85289): 0 Smith-Waterman score: 6776; 99.9% identity (100.0% similar) in 1017 aa overlap (1-1017:1-1017) 10 20 30 40 50 60 pF1KA1 MMSEGKPPDKKRPRRSLSISKNKKKASNSIISCFNNAPPAKLACPVCSKMVPRYDLNRHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MMSEGKPPDKKRPRRSLSISKNKKKASNSIISCFNNAPPAKLACPVCSKMVPRYDLNRHL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 DEMCANNDFVQVDPGQVGLINSNVSMVDLTSVTLEDVTPKKSPPPKTNLTPGQSDSAKRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 DEMCANNDFVQVDPGQVGLINSNVSMVDLTSVTLEDVTPKKSPPPKTNLTPGQSDSAKRE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 VKQKISPYFKSNDVVCKNQDELRNRSVKVICLGSLASKLSRKYVKAKKSIDKDEEFAGSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VKQKISPYFKSNDVVCKNQDELRNRSVKVICLGSLASKLSRKYVKAKKSIDKDEEFAGSS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 PQSSKSTVVKSLIDNSSEIEDEDQILENSSQKENVFKCDSLKEECIPEHMVRGSKIMEAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PQSSKSTVVKSLIDNSSEIEDEDQILENSSQKENVFKCDSLKEECIPEHMVRGSKIMEAE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 SQKATRECEKSALTPGFSDNAIMLFSPDFTLRNTLKSTSEDSLVKQECIKEVVEKREACH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SQKATRECEKSALTPGFSDNAIMLFSPDFTLRNTLKSTSEDSLVKQECIKEVVEKREACH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 CEEVKMTVASEAKIQLSDSEAKSHSSADDASAWSNIQEAPLQDDSCLNNDIPHSIPLEQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 CEEVKMTVASEAKIQLSDSEAKSHSSADDASAWSNIQEAPLQDDSCLNNDIPHSIPLEQG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 SSCNGPGQTTGHPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SSCNGPGQTTGHPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYVR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 LFQRKLSWIKMTKLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LFQRKLSWIKMTKLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKSL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 AKTFHLANPNGQKQQLVDAFLKLAKQRSVCTWGKNKPGIGAVILKRAKALAGQSVRICKG ::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 AKTFHLVNPNGQKQQLVDAFLKLAKQRSVCTWGKNKPGIGAVILKRAKALAGQSVRICKG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 PRAVFSRILLLFSLTDSMEDEDAACGGQGQLSTVLLVNLGRMEFPSYTINRKTHIFQDRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PRAVFSRILLLFSLTDSMEDEDAACGGQGQLSTVLLVNLGRMEFPSYTINRKTHIFQDRD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 DLIRYAAATHMLSDISSAMANGNWEEAKELAQCAKRDWNRLKNHPSLRCHEDLPLFLRCF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 DLIRYAAATHMLSDISSAMANGNWEEAKELAQCAKRDWNRLKNHPSLRCHEDLPLFLRCF 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 TVGWIYTRILSRFVEILQRLHMYEEAVRELESLLSQRIYCPDSRGRWWDRLALNLHQHLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TVGWIYTRILSRFVEILQRLHMYEEAVRELESLLSQRIYCPDSRGRWWDRLALNLHQHLK 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 RLEPTIKCITEGLADPEVRTGHRLSLYQRAVRLRESPSCKKFKHLFQQLPEMAVQDVKHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 RLEPTIKCITEGLADPEVRTGHRLSLYQRAVRLRESPSCKKFKHLFQQLPEMAVQDVKHV 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 TITGRLCPQRGMCKSVFVMEAGEAADPTTVLCSVEELALAHYRRSGFDQGIHGEGSTFST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TITGRLCPQRGMCKSVFVMEAGEAADPTTVLCSVEELALAHYRRSGFDQGIHGEGSTFST 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 LYGLLLWDIIFMDGIPDVFRNACQAFPLDLCTDSFFTSRRPALEARLQLIHDAPEESLRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LYGLLLWDIIFMDGIPDVFRNACQAFPLDLCTDSFFTSRRPALEARLQLIHDAPEESLRA 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 WVAATWHEQEGRVASLVSWDRFTSLQQAQDLVSCLGGPVLSGVCRHLAADFRHCRGGLPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 WVAATWHEQEGRVASLVSWDRFTSLQQAQDLVSCLGGPVLSGVCRHLAADFRHCRGGLPD 910 920 930 940 950 960 970 980 990 1000 1010 pF1KA1 LVVWNSQSRHFKLVEVKGPNDRLSHKQMIWLAELQKLGAEVEVCHVVAVGAKSQSLS ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LVVWNSQSRHFKLVEVKGPNDRLSHKQMIWLAELQKLGAEVEVCHVVAVGAKSQSLS 970 980 990 1000 1010 >>XP_011519673 (OMIM: 613534,614817) PREDICTED: fanconi- (622 aa) initn: 4077 init1: 4077 opt: 4077 Z-score: 4200.7 bits: 788.1 E(85289): 0 Smith-Waterman score: 4077; 99.7% identity (100.0% similar) in 607 aa overlap (411-1017:16-622) 390 400 410 420 430 440 pF1KA1 VVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYVRLFQRKLSWIKMTKLEYEEIA .::::::::::::::::::::::::::::: XP_011 MPEVLGSQGWLQASSAATGQKLYVRLFQRKLSWIKMTKLEYEEIA 10 20 30 40 450 460 470 480 490 500 pF1KA1 LDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKSLAKTFHLANPNGQKQQLVDAF ::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::: XP_011 LDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKSLAKTFHLVNPNGQKQQLVDAF 50 60 70 80 90 100 510 520 530 540 550 560 pF1KA1 LKLAKQRSVCTWGKNKPGIGAVILKRAKALAGQSVRICKGPRAVFSRILLLFSLTDSMED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKLAKQRSVCTWGKNKPGIGAVILKRAKALAGQSVRICKGPRAVFSRILLLFSLTDSMED 110 120 130 140 150 160 570 580 590 600 610 620 pF1KA1 EDAACGGQGQLSTVLLVNLGRMEFPSYTINRKTHIFQDRDDLIRYAAATHMLSDISSAMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EDAACGGQGQLSTVLLVNLGRMEFPSYTINRKTHIFQDRDDLIRYAAATHMLSDISSAMA 170 180 190 200 210 220 630 640 650 660 670 680 pF1KA1 NGNWEEAKELAQCAKRDWNRLKNHPSLRCHEDLPLFLRCFTVGWIYTRILSRFVEILQRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NGNWEEAKELAQCAKRDWNRLKNHPSLRCHEDLPLFLRCFTVGWIYTRILSRFVEILQRL 230 240 250 260 270 280 690 700 710 720 730 740 pF1KA1 HMYEEAVRELESLLSQRIYCPDSRGRWWDRLALNLHQHLKRLEPTIKCITEGLADPEVRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HMYEEAVRELESLLSQRIYCPDSRGRWWDRLALNLHQHLKRLEPTIKCITEGLADPEVRT 290 300 310 320 330 340 750 760 770 780 790 800 pF1KA1 GHRLSLYQRAVRLRESPSCKKFKHLFQQLPEMAVQDVKHVTITGRLCPQRGMCKSVFVME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GHRLSLYQRAVRLRESPSCKKFKHLFQQLPEMAVQDVKHVTITGRLCPQRGMCKSVFVME 350 360 370 380 390 400 810 820 830 840 850 860 pF1KA1 AGEAADPTTVLCSVEELALAHYRRSGFDQGIHGEGSTFSTLYGLLLWDIIFMDGIPDVFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AGEAADPTTVLCSVEELALAHYRRSGFDQGIHGEGSTFSTLYGLLLWDIIFMDGIPDVFR 410 420 430 440 450 460 870 880 890 900 910 920 pF1KA1 NACQAFPLDLCTDSFFTSRRPALEARLQLIHDAPEESLRAWVAATWHEQEGRVASLVSWD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NACQAFPLDLCTDSFFTSRRPALEARLQLIHDAPEESLRAWVAATWHEQEGRVASLVSWD 470 480 490 500 510 520 930 940 950 960 970 980 pF1KA1 RFTSLQQAQDLVSCLGGPVLSGVCRHLAADFRHCRGGLPDLVVWNSQSRHFKLVEVKGPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RFTSLQQAQDLVSCLGGPVLSGVCRHLAADFRHCRGGLPDLVVWNSQSRHFKLVEVKGPN 530 540 550 560 570 580 990 1000 1010 pF1KA1 DRLSHKQMIWLAELQKLGAEVEVCHVVAVGAKSQSLS ::::::::::::::::::::::::::::::::::::: XP_011 DRLSHKQMIWLAELQKLGAEVEVCHVVAVGAKSQSLS 590 600 610 620 >>XP_011519672 (OMIM: 613534,614817) PREDICTED: fanconi- (623 aa) initn: 4071 init1: 4071 opt: 4072 Z-score: 4195.6 bits: 787.2 E(85289): 0 Smith-Waterman score: 4072; 98.4% identity (99.3% similar) in 615 aa overlap (403-1017:9-623) 380 390 400 410 420 430 pF1KA1 PYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYVRLFQRKLSWIKMT .: . . ..:::::::::::::::::::: XP_011 MRSYRIPLLVISSQESKTTGQKLYVRLFQRKLSWIKMT 10 20 30 440 450 460 470 480 490 pF1KA1 KLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKSLAKTFHLANPNGQ ::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::: XP_011 KLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKSLAKTFHLVNPNGQ 40 50 60 70 80 90 500 510 520 530 540 550 pF1KA1 KQQLVDAFLKLAKQRSVCTWGKNKPGIGAVILKRAKALAGQSVRICKGPRAVFSRILLLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KQQLVDAFLKLAKQRSVCTWGKNKPGIGAVILKRAKALAGQSVRICKGPRAVFSRILLLF 100 110 120 130 140 150 560 570 580 590 600 610 pF1KA1 SLTDSMEDEDAACGGQGQLSTVLLVNLGRMEFPSYTINRKTHIFQDRDDLIRYAAATHML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLTDSMEDEDAACGGQGQLSTVLLVNLGRMEFPSYTINRKTHIFQDRDDLIRYAAATHML 160 170 180 190 200 210 620 630 640 650 660 670 pF1KA1 SDISSAMANGNWEEAKELAQCAKRDWNRLKNHPSLRCHEDLPLFLRCFTVGWIYTRILSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SDISSAMANGNWEEAKELAQCAKRDWNRLKNHPSLRCHEDLPLFLRCFTVGWIYTRILSR 220 230 240 250 260 270 680 690 700 710 720 730 pF1KA1 FVEILQRLHMYEEAVRELESLLSQRIYCPDSRGRWWDRLALNLHQHLKRLEPTIKCITEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FVEILQRLHMYEEAVRELESLLSQRIYCPDSRGRWWDRLALNLHQHLKRLEPTIKCITEG 280 290 300 310 320 330 740 750 760 770 780 790 pF1KA1 LADPEVRTGHRLSLYQRAVRLRESPSCKKFKHLFQQLPEMAVQDVKHVTITGRLCPQRGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LADPEVRTGHRLSLYQRAVRLRESPSCKKFKHLFQQLPEMAVQDVKHVTITGRLCPQRGM 340 350 360 370 380 390 800 810 820 830 840 850 pF1KA1 CKSVFVMEAGEAADPTTVLCSVEELALAHYRRSGFDQGIHGEGSTFSTLYGLLLWDIIFM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CKSVFVMEAGEAADPTTVLCSVEELALAHYRRSGFDQGIHGEGSTFSTLYGLLLWDIIFM 400 410 420 430 440 450 860 870 880 890 900 910 pF1KA1 DGIPDVFRNACQAFPLDLCTDSFFTSRRPALEARLQLIHDAPEESLRAWVAATWHEQEGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DGIPDVFRNACQAFPLDLCTDSFFTSRRPALEARLQLIHDAPEESLRAWVAATWHEQEGR 460 470 480 490 500 510 920 930 940 950 960 970 pF1KA1 VASLVSWDRFTSLQQAQDLVSCLGGPVLSGVCRHLAADFRHCRGGLPDLVVWNSQSRHFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VASLVSWDRFTSLQQAQDLVSCLGGPVLSGVCRHLAADFRHCRGGLPDLVVWNSQSRHFK 520 530 540 550 560 570 980 990 1000 1010 pF1KA1 LVEVKGPNDRLSHKQMIWLAELQKLGAEVEVCHVVAVGAKSQSLS ::::::::::::::::::::::::::::::::::::::::::::: XP_011 LVEVKGPNDRLSHKQMIWLAELQKLGAEVEVCHVVAVGAKSQSLS 580 590 600 610 620 >>XP_011519674 (OMIM: 613534,614817) PREDICTED: fanconi- (609 aa) initn: 3930 init1: 3930 opt: 3930 Z-score: 4049.4 bits: 760.1 E(85289): 8.1e-219 Smith-Waterman score: 3930; 99.8% identity (100.0% similar) in 604 aa overlap (1-604:1-604) 10 20 30 40 50 60 pF1KA1 MMSEGKPPDKKRPRRSLSISKNKKKASNSIISCFNNAPPAKLACPVCSKMVPRYDLNRHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MMSEGKPPDKKRPRRSLSISKNKKKASNSIISCFNNAPPAKLACPVCSKMVPRYDLNRHL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 DEMCANNDFVQVDPGQVGLINSNVSMVDLTSVTLEDVTPKKSPPPKTNLTPGQSDSAKRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DEMCANNDFVQVDPGQVGLINSNVSMVDLTSVTLEDVTPKKSPPPKTNLTPGQSDSAKRE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 VKQKISPYFKSNDVVCKNQDELRNRSVKVICLGSLASKLSRKYVKAKKSIDKDEEFAGSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VKQKISPYFKSNDVVCKNQDELRNRSVKVICLGSLASKLSRKYVKAKKSIDKDEEFAGSS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 PQSSKSTVVKSLIDNSSEIEDEDQILENSSQKENVFKCDSLKEECIPEHMVRGSKIMEAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PQSSKSTVVKSLIDNSSEIEDEDQILENSSQKENVFKCDSLKEECIPEHMVRGSKIMEAE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 SQKATRECEKSALTPGFSDNAIMLFSPDFTLRNTLKSTSEDSLVKQECIKEVVEKREACH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SQKATRECEKSALTPGFSDNAIMLFSPDFTLRNTLKSTSEDSLVKQECIKEVVEKREACH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 CEEVKMTVASEAKIQLSDSEAKSHSSADDASAWSNIQEAPLQDDSCLNNDIPHSIPLEQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CEEVKMTVASEAKIQLSDSEAKSHSSADDASAWSNIQEAPLQDDSCLNNDIPHSIPLEQG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 SSCNGPGQTTGHPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSCNGPGQTTGHPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYVR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 LFQRKLSWIKMTKLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LFQRKLSWIKMTKLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKSL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 AKTFHLANPNGQKQQLVDAFLKLAKQRSVCTWGKNKPGIGAVILKRAKALAGQSVRICKG ::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AKTFHLVNPNGQKQQLVDAFLKLAKQRSVCTWGKNKPGIGAVILKRAKALAGQSVRICKG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 PRAVFSRILLLFSLTDSMEDEDAACGGQGQLSTVLLVNLGRMEFPSYTINRKTHIFQDRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PRAVFSRILLLFSLTDSMEDEDAACGGQGQLSTVLLVNLGRMEFPSYTINRKTHIFQDRD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 DLIRYAAATHMLSDISSAMANGNWEEAKELAQCAKRDWNRLKNHPSLRCHEDLPLFLRCF :::: XP_011 DLIRVRSSG >>NP_001139567 (OMIM: 613534,614817) fanconi-associated (533 aa) initn: 3422 init1: 3422 opt: 3422 Z-score: 3527.0 bits: 663.2 E(85289): 1e-189 Smith-Waterman score: 3422; 99.8% identity (100.0% similar) in 526 aa overlap (1-526:1-526) 10 20 30 40 50 60 pF1KA1 MMSEGKPPDKKRPRRSLSISKNKKKASNSIISCFNNAPPAKLACPVCSKMVPRYDLNRHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MMSEGKPPDKKRPRRSLSISKNKKKASNSIISCFNNAPPAKLACPVCSKMVPRYDLNRHL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 DEMCANNDFVQVDPGQVGLINSNVSMVDLTSVTLEDVTPKKSPPPKTNLTPGQSDSAKRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DEMCANNDFVQVDPGQVGLINSNVSMVDLTSVTLEDVTPKKSPPPKTNLTPGQSDSAKRE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 VKQKISPYFKSNDVVCKNQDELRNRSVKVICLGSLASKLSRKYVKAKKSIDKDEEFAGSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VKQKISPYFKSNDVVCKNQDELRNRSVKVICLGSLASKLSRKYVKAKKSIDKDEEFAGSS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 PQSSKSTVVKSLIDNSSEIEDEDQILENSSQKENVFKCDSLKEECIPEHMVRGSKIMEAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PQSSKSTVVKSLIDNSSEIEDEDQILENSSQKENVFKCDSLKEECIPEHMVRGSKIMEAE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 SQKATRECEKSALTPGFSDNAIMLFSPDFTLRNTLKSTSEDSLVKQECIKEVVEKREACH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SQKATRECEKSALTPGFSDNAIMLFSPDFTLRNTLKSTSEDSLVKQECIKEVVEKREACH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 CEEVKMTVASEAKIQLSDSEAKSHSSADDASAWSNIQEAPLQDDSCLNNDIPHSIPLEQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CEEVKMTVASEAKIQLSDSEAKSHSSADDASAWSNIQEAPLQDDSCLNNDIPHSIPLEQG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 SSCNGPGQTTGHPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSCNGPGQTTGHPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYVR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 LFQRKLSWIKMTKLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LFQRKLSWIKMTKLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKSL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 AKTFHLANPNGQKQQLVDAFLKLAKQRSVCTWGKNKPGIGAVILKRAKALAGQSVRICKG ::::::.::::::::::::::::::::::::::::::::::::::: NP_001 AKTFHLVNPNGQKQQLVDAFLKLAKQRSVCTWGKNKPGIGAVILKRFCWLLLQ 490 500 510 520 530 550 560 570 580 590 600 pF1KA1 PRAVFSRILLLFSLTDSMEDEDAACGGQGQLSTVLLVNLGRMEFPSYTINRKTHIFQDRD >>NP_001139566 (OMIM: 613534,614817) fanconi-associated (533 aa) initn: 3422 init1: 3422 opt: 3422 Z-score: 3527.0 bits: 663.2 E(85289): 1e-189 Smith-Waterman score: 3422; 99.8% identity (100.0% similar) in 526 aa overlap (1-526:1-526) 10 20 30 40 50 60 pF1KA1 MMSEGKPPDKKRPRRSLSISKNKKKASNSIISCFNNAPPAKLACPVCSKMVPRYDLNRHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MMSEGKPPDKKRPRRSLSISKNKKKASNSIISCFNNAPPAKLACPVCSKMVPRYDLNRHL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 DEMCANNDFVQVDPGQVGLINSNVSMVDLTSVTLEDVTPKKSPPPKTNLTPGQSDSAKRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DEMCANNDFVQVDPGQVGLINSNVSMVDLTSVTLEDVTPKKSPPPKTNLTPGQSDSAKRE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 VKQKISPYFKSNDVVCKNQDELRNRSVKVICLGSLASKLSRKYVKAKKSIDKDEEFAGSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VKQKISPYFKSNDVVCKNQDELRNRSVKVICLGSLASKLSRKYVKAKKSIDKDEEFAGSS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 PQSSKSTVVKSLIDNSSEIEDEDQILENSSQKENVFKCDSLKEECIPEHMVRGSKIMEAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PQSSKSTVVKSLIDNSSEIEDEDQILENSSQKENVFKCDSLKEECIPEHMVRGSKIMEAE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 SQKATRECEKSALTPGFSDNAIMLFSPDFTLRNTLKSTSEDSLVKQECIKEVVEKREACH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SQKATRECEKSALTPGFSDNAIMLFSPDFTLRNTLKSTSEDSLVKQECIKEVVEKREACH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 CEEVKMTVASEAKIQLSDSEAKSHSSADDASAWSNIQEAPLQDDSCLNNDIPHSIPLEQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CEEVKMTVASEAKIQLSDSEAKSHSSADDASAWSNIQEAPLQDDSCLNNDIPHSIPLEQG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 SSCNGPGQTTGHPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSCNGPGQTTGHPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYVR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 LFQRKLSWIKMTKLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LFQRKLSWIKMTKLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKSL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 AKTFHLANPNGQKQQLVDAFLKLAKQRSVCTWGKNKPGIGAVILKRAKALAGQSVRICKG ::::::.::::::::::::::::::::::::::::::::::::::: NP_001 AKTFHLVNPNGQKQQLVDAFLKLAKQRSVCTWGKNKPGIGAVILKRFCWLLLQ 490 500 510 520 530 550 560 570 580 590 600 pF1KA1 PRAVFSRILLLFSLTDSMEDEDAACGGQGQLSTVLLVNLGRMEFPSYTINRKTHIFQDRD >>NP_001139568 (OMIM: 613534,614817) fanconi-associated (533 aa) initn: 3422 init1: 3422 opt: 3422 Z-score: 3527.0 bits: 663.2 E(85289): 1e-189 Smith-Waterman score: 3422; 99.8% identity (100.0% similar) in 526 aa overlap (1-526:1-526) 10 20 30 40 50 60 pF1KA1 MMSEGKPPDKKRPRRSLSISKNKKKASNSIISCFNNAPPAKLACPVCSKMVPRYDLNRHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MMSEGKPPDKKRPRRSLSISKNKKKASNSIISCFNNAPPAKLACPVCSKMVPRYDLNRHL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 DEMCANNDFVQVDPGQVGLINSNVSMVDLTSVTLEDVTPKKSPPPKTNLTPGQSDSAKRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DEMCANNDFVQVDPGQVGLINSNVSMVDLTSVTLEDVTPKKSPPPKTNLTPGQSDSAKRE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 VKQKISPYFKSNDVVCKNQDELRNRSVKVICLGSLASKLSRKYVKAKKSIDKDEEFAGSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VKQKISPYFKSNDVVCKNQDELRNRSVKVICLGSLASKLSRKYVKAKKSIDKDEEFAGSS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 PQSSKSTVVKSLIDNSSEIEDEDQILENSSQKENVFKCDSLKEECIPEHMVRGSKIMEAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PQSSKSTVVKSLIDNSSEIEDEDQILENSSQKENVFKCDSLKEECIPEHMVRGSKIMEAE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 SQKATRECEKSALTPGFSDNAIMLFSPDFTLRNTLKSTSEDSLVKQECIKEVVEKREACH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SQKATRECEKSALTPGFSDNAIMLFSPDFTLRNTLKSTSEDSLVKQECIKEVVEKREACH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 CEEVKMTVASEAKIQLSDSEAKSHSSADDASAWSNIQEAPLQDDSCLNNDIPHSIPLEQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CEEVKMTVASEAKIQLSDSEAKSHSSADDASAWSNIQEAPLQDDSCLNNDIPHSIPLEQG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 SSCNGPGQTTGHPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSCNGPGQTTGHPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYVR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 LFQRKLSWIKMTKLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LFQRKLSWIKMTKLEYEEIALDLTPVIEELTNAGFLQTESELQELSEVLELLSAPELKSL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 AKTFHLANPNGQKQQLVDAFLKLAKQRSVCTWGKNKPGIGAVILKRAKALAGQSVRICKG ::::::.::::::::::::::::::::::::::::::::::::::: NP_001 AKTFHLVNPNGQKQQLVDAFLKLAKQRSVCTWGKNKPGIGAVILKRFCWLLLQ 490 500 510 520 530 550 560 570 580 590 600 pF1KA1 PRAVFSRILLLFSLTDSMEDEDAACGGQGQLSTVLLVNLGRMEFPSYTINRKTHIFQDRD 1017 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 10:40:35 2016 done: Thu Nov 3 10:40:37 2016 Total Scan time: 14.370 Total Display time: 0.270 Function used was FASTA [36.3.4 Apr, 2011]