FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1041, 622 aa 1>>>pF1KA1041 622 - 622 aa - 622 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.9338+/-0.00113; mu= -5.2490+/- 0.068 mean_var=326.0357+/-67.117, 0's: 0 Z-trim(113.9): 91 B-trim: 377 in 1/51 Lambda= 0.071030 statistics sampled from 14444 (14525) to 14444 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.75), E-opt: 0.2 (0.446), width: 16 Scan time: 4.050 The best scores are: opt bits E(32554) CCDS30689.1 FOXJ3 gene_id:22887|Hs108|chr1 ( 622) 4282 452.7 6.7e-127 CCDS55594.1 FOXJ3 gene_id:22887|Hs108|chr1 ( 588) 2887 309.7 7e-84 CCDS8587.1 FOXJ2 gene_id:55810|Hs108|chr12 ( 574) 793 95.1 2.7e-19 >>CCDS30689.1 FOXJ3 gene_id:22887|Hs108|chr1 (622 aa) initn: 4282 init1: 4282 opt: 4282 Z-score: 2391.7 bits: 452.7 E(32554): 6.7e-127 Smith-Waterman score: 4282; 99.7% identity (99.8% similar) in 622 aa overlap (1-622:1-622) 10 20 30 40 50 60 pF1KA1 MGLYGQACPSVTSLRMTSELESSLTSMDWLPQLTMRAAIQKSDATQNAHGTGISKKNALL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 MGLYGQACPSVTSLRMTSELESSLTSMDWLPQLTMRAAIQKSDATQNAHGTGISKKNALL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 DPNTTLDQEEVQQHKDGKPPYSYASLITFAINSSPKKKMTLSEIYQWICDNFPYYREAGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 DPNTTLDQEEVQQHKDGKPPYSYASLITFAINSSPKKKMTLSEIYQWICDNFPYYREAGS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 GWKNSIRHNLSLNKCFLKVPRSKDDPGKGSYWAIDTNPKEDALPTRPKKRARSVERASTP :::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::: CCDS30 GWKNSIRHNLSLNKCFLKVPRSKDDPGKGSYWAIDTNPKEDVLPTRPKKRARSVERASTP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 YSIDSDSLGMECIISGSASPTLAINTVTNKVTLYNTDQDGSDSPRSSLNNSLSDQSLASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 YSIDSDSLGMECIISGSASPTLAINTVTNKVTLYNTDQDGSDSPRSSLNNSLSDQSLASV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 NLNSVGSVHSYTPVTSHPESVSQSLTPQQQPQYNLPERDKQLLFSEYNFEDLSASFRSLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 NLNSVGSVHSYTPVTSHPESVSQSLTPQQQPQYNLPERDKQLLFSEYNFEDLSASFRSLY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 KSVFEQSLSQQGLMNIPSESSQQSHTSCTYQHSPSSTVSTHPHSNQSSLSNSHGSGLNTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 KSVFEQSLSQQGLMNIPSESSQQSHTSCTYQHSPSSTVSTHPHSNQSSLSNSHGSGLNTT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 GSNSVAQVSLSHPQMHPQPSPHPPHRPHGLPQHPQRSPHPAPHPQQHSQLQSPHPQHPSP :::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::: CCDS30 GSNSVAQVSLSHPQMHTQPSPHPPHRPHGLPQHPQRSPHPAPHPQQHSQLQSPHPQHPSP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 HQHIQHHPNHQHQTLTHQAPPPPQQVSCNSGVSNDWYATLDMLKESCRIASSVNWSDVDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 HQHIQHHPNHQHQTLTHQAPPPPQQVSCNSGVSNDWYATLDMLKESCRIASSVNWSDVDL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 SQFQGLMESMRQADLKNWSLDQVQFADLCSSLNQFFTQTGLIHSQSNVQQNVCHGAMHPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 SQFQGLMESMRQADLKNWSLDQVQFADLCSSLNQFFTQTGLIHSQSNVQQNVCHGAMHPT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 KPSQHIGTGNLYIDSRQNLPPSVMPPPGYPHIPQALSTPGTTMAGHHRAMNQQHMMPSQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 KPSQHIGTGNLYIDSRQNLPPSVMPPPGYPHIPQALSTPGTTMAGHHRAMNQQHMMPSQA 550 560 570 580 590 600 610 620 pF1KA1 FQMRRSLPPDDIQDDFDWDSIV :::::::::::::::::::::: CCDS30 FQMRRSLPPDDIQDDFDWDSIV 610 620 >>CCDS55594.1 FOXJ3 gene_id:22887|Hs108|chr1 (588 aa) initn: 2887 init1: 2887 opt: 2887 Z-score: 1619.5 bits: 309.7 E(32554): 7e-84 Smith-Waterman score: 3993; 94.2% identity (94.4% similar) in 622 aa overlap (1-622:1-588) 10 20 30 40 50 60 pF1KA1 MGLYGQACPSVTSLRMTSELESSLTSMDWLPQLTMRAAIQKSDATQNAHGTGISKKNALL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 MGLYGQACPSVTSLRMTSELESSLTSMDWLPQLTMRAAIQKSDATQNAHGTGISKKNALL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 DPNTTLDQEEVQQHKDGKPPYSYASLITFAINSSPKKKMTLSEIYQWICDNFPYYREAGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 DPNTTLDQEEVQQHKDGKPPYSYASLITFAINSSPKKKMTLSEIYQWICDNFPYYREAGS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 GWKNSIRHNLSLNKCFLKVPRSKDDPGKGSYWAIDTNPKEDALPTRPKKRARSVERASTP :::::::::::::::::::::::::::::::::::::::::.:::::::::::::: CCDS55 GWKNSIRHNLSLNKCFLKVPRSKDDPGKGSYWAIDTNPKEDVLPTRPKKRARSVER---- 130 140 150 160 170 190 200 210 220 230 240 pF1KA1 YSIDSDSLGMECIISGSASPTLAINTVTNKVTLYNTDQDGSDSPRSSLNNSLSDQSLASV :::::::::::::::::::::::::::::: CCDS55 ------------------------------VTLYNTDQDGSDSPRSSLNNSLSDQSLASV 180 190 200 250 260 270 280 290 300 pF1KA1 NLNSVGSVHSYTPVTSHPESVSQSLTPQQQPQYNLPERDKQLLFSEYNFEDLSASFRSLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 NLNSVGSVHSYTPVTSHPESVSQSLTPQQQPQYNLPERDKQLLFSEYNFEDLSASFRSLY 210 220 230 240 250 260 310 320 330 340 350 360 pF1KA1 KSVFEQSLSQQGLMNIPSESSQQSHTSCTYQHSPSSTVSTHPHSNQSSLSNSHGSGLNTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 KSVFEQSLSQQGLMNIPSESSQQSHTSCTYQHSPSSTVSTHPHSNQSSLSNSHGSGLNTT 270 280 290 300 310 320 370 380 390 400 410 420 pF1KA1 GSNSVAQVSLSHPQMHPQPSPHPPHRPHGLPQHPQRSPHPAPHPQQHSQLQSPHPQHPSP :::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::: CCDS55 GSNSVAQVSLSHPQMHTQPSPHPPHRPHGLPQHPQRSPHPAPHPQQHSQLQSPHPQHPSP 330 340 350 360 370 380 430 440 450 460 470 480 pF1KA1 HQHIQHHPNHQHQTLTHQAPPPPQQVSCNSGVSNDWYATLDMLKESCRIASSVNWSDVDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 HQHIQHHPNHQHQTLTHQAPPPPQQVSCNSGVSNDWYATLDMLKESCRIASSVNWSDVDL 390 400 410 420 430 440 490 500 510 520 530 540 pF1KA1 SQFQGLMESMRQADLKNWSLDQVQFADLCSSLNQFFTQTGLIHSQSNVQQNVCHGAMHPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 SQFQGLMESMRQADLKNWSLDQVQFADLCSSLNQFFTQTGLIHSQSNVQQNVCHGAMHPT 450 460 470 480 490 500 550 560 570 580 590 600 pF1KA1 KPSQHIGTGNLYIDSRQNLPPSVMPPPGYPHIPQALSTPGTTMAGHHRAMNQQHMMPSQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 KPSQHIGTGNLYIDSRQNLPPSVMPPPGYPHIPQALSTPGTTMAGHHRAMNQQHMMPSQA 510 520 530 540 550 560 610 620 pF1KA1 FQMRRSLPPDDIQDDFDWDSIV :::::::::::::::::::::: CCDS55 FQMRRSLPPDDIQDDFDWDSIV 570 580 >>CCDS8587.1 FOXJ2 gene_id:55810|Hs108|chr12 (574 aa) initn: 1146 init1: 562 opt: 793 Z-score: 459.9 bits: 95.1 E(32554): 2.7e-19 Smith-Waterman score: 1237; 39.5% identity (62.7% similar) in 635 aa overlap (16-621:1-573) 10 20 30 40 50 pF1KA1 MGLYGQACPSVTSLRMTSELESSLTSMDWLPQLTMRAAIQKSDATQNAHGTGISKK---N :.:.:::::::.:::::::.::.:.: ....: : :.: . CCDS85 MASDLESSLTSIDWLPQLTLRATIEKLGSASQAGPPGSSRKCSPG 10 20 30 40 60 70 80 90 100 110 pF1KA1 ALLDPNTTLDQEEVQQHKDGKPPYSYASLITFAINSSPKKKMTLSEIYQWICDNFPYYRE . :::.::...:. :.:::: ::::.:::.:::::: :::::::::.:::::::::.. CCDS85 SPTDPNATLSKDEAAVHQDGKPRYSYATLITYAINSSPAKKMTLSEIYRWICDNFPYYKN 50 60 70 80 90 100 120 130 140 150 160 170 pF1KA1 AGSGWKNSIRHNLSLNKCFLKVPRSKDDPGKGSYWAIDTNPKEDALPTRPKKRARSVERA :: :::::::::::::::: :::: .:::::::::.::: : : .:: : CCDS85 AGIGWKNSIRHNLSLNKCFRKVPRPRDDPGKGSYWTIDTCP--DI----SRKR-----RH 110 120 130 140 150 180 190 200 210 220 230 pF1KA1 STPYSIDSDSLGMECIISGSASPTLAINTVTNKVTLYNTDQDGSDSPRSSLNNSLSDQSL ....:: .: .: :: .. .....: .:. :. ::. : :. CCDS85 PPDDDLSQDSPEQE----ASKSPRGGVAG-SGEASL---PPEGN--PQMSLQ---SPTSI 160 170 180 190 200 240 250 260 270 280 290 pF1KA1 ASVNLNSVGSVHSYTPVTSHPESVSQSLTPQQQPQYNLPERDKQLLFSEYNFEDLSASFR :: . ...::: . . ... : : : :: ..: .. .:: ::.::: ::: CCDS85 ASYS-QGTGSVDGGAVAAGASGRESAEGPP---PLYNT-NHDFKFSYSEINFQDLSWSFR 210 220 230 240 250 300 310 320 330 340 350 pF1KA1 SLYKSVFEQSLSQQGLMNIPSESSQQSHTSCTYQHSPSSTVSTHPHSNQSSLSNSHGSGL .::::..:.: : :::.. .: . ::.. . ...:. .. . CCDS85 NLYKSMLEKS----------SSSSQHGFSSLLGDIPPSNNY--YMYQQQQPPPPQQQQQQ 260 270 280 290 300 360 370 380 390 400 410 pF1KA1 NTTGSNSVAQVSLSHPQMHPQPSPHPPHRPHGLPQH-PQRSPHPAPHPQQH-SQLQSPHP . . : :.::.. :. : . : : :. . : .: .. .: : CCDS85 QQPPQPPPQQ---SQPQQQQAPAQGPSAVGGAPPLHTPSTDGCTPPGGKQAGAEGYGPPP 310 320 330 340 350 360 420 430 440 450 460 pF1KA1 ---QHPSPHQHIQHHPNHQHQTLTH--QAPPPPQ-QVSCNSGVSN-------DWYATLDM .:: : :: .:: :::. .: : ::::: :.. .. ..: :: ...: CCDS85 VMAMHPPPLQHGGYHP-HQHHPHSHPAQQPPPPQPQAQGQAPINNTGFAFPSDWCSNIDS 370 380 390 400 410 420 470 480 490 500 510 520 pF1KA1 LKESCRIASSVNWSDVDLSQFQGLMESMRQADLKNWSLDQVQFADLCSSLNQFFTQTGLI :::: .... .:::... :::. ::::.:::. :::.::: ..:.::.:::.:.:::: . CCDS85 LKESFKMVNRLNWSSIEQSQFSELMESLRQAEQKNWTLDQHHIANLCDSLNHFLTQTGHV 430 440 450 460 470 480 530 540 550 560 570 580 pF1KA1 HSQSNVQQNVCHGAMHPTKPSQHIGTGNLYIDSRQNLPPSVMPPPGYPHIPQALSTPGTT :. :. .: :.. :. . ...:. : . :.:. :. :. CCDS85 PPQG--------GTHRPPAPAR-IADSCALTSGKQESAMSQVNSYGHPQAPHLYPGPSPM 490 500 510 520 530 590 600 610 620 pF1KA1 M-------AGHHRAMNQQHMMPSQAFQMRRSLPP----DDIQDDFDWDSIV . ::..: .::.: : :.:: ..: :::::: : CCDS85 YPIPTQDSAGYNRPA--HHMVP------RPSVPPPGANEEIPDDFDWDLIT 540 550 560 570 622 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 01:19:10 2016 done: Fri Nov 4 01:19:11 2016 Total Scan time: 4.050 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]