FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1070, 823 aa 1>>>pF1KA1070 823 - 823 aa - 823 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.1461+/-0.000333; mu= 17.6679+/- 0.021 mean_var=89.8918+/-18.455, 0's: 0 Z-trim(115.8): 109 B-trim: 0 in 0/53 Lambda= 0.135274 statistics sampled from 26378 (26487) to 26378 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.66), E-opt: 0.2 (0.311), width: 16 Scan time: 11.960 The best scores are: opt bits E(85289) XP_016861387 (OMIM: 600568) PREDICTED: neuroligin- ( 823) 5668 1116.6 0 XP_016861390 (OMIM: 600568) PREDICTED: neuroligin- ( 823) 5668 1116.6 0 XP_016861388 (OMIM: 600568) PREDICTED: neuroligin- ( 823) 5668 1116.6 0 NP_055747 (OMIM: 600568) neuroligin-1 [Homo sapien ( 823) 5668 1116.6 0 XP_016861389 (OMIM: 600568) PREDICTED: neuroligin- ( 823) 5668 1116.6 0 XP_005247292 (OMIM: 600568) PREDICTED: neuroligin- ( 823) 5668 1116.6 0 XP_005247291 (OMIM: 600568) PREDICTED: neuroligin- ( 823) 5668 1116.6 0 XP_005247294 (OMIM: 600568) PREDICTED: neuroligin- ( 671) 4515 891.5 0 XP_016861381 (OMIM: 600568) PREDICTED: neuroligin- ( 843) 4509 890.4 0 XP_016861378 (OMIM: 600568) PREDICTED: neuroligin- ( 843) 4509 890.4 0 XP_016861380 (OMIM: 600568) PREDICTED: neuroligin- ( 843) 4509 890.4 0 XP_016861379 (OMIM: 600568) PREDICTED: neuroligin- ( 843) 4509 890.4 0 XP_006713603 (OMIM: 600568) PREDICTED: neuroligin- ( 843) 4508 890.2 0 XP_011510853 (OMIM: 600568) PREDICTED: neuroligin- ( 843) 4508 890.2 0 XP_016861377 (OMIM: 600568) PREDICTED: neuroligin- ( 843) 4508 890.2 0 XP_016861382 (OMIM: 600568) PREDICTED: neuroligin- ( 843) 4508 890.2 0 XP_016861383 (OMIM: 600568) PREDICTED: neuroligin- ( 843) 4508 890.2 0 XP_016861384 (OMIM: 600568) PREDICTED: neuroligin- ( 843) 4508 890.2 0 XP_016861385 (OMIM: 600568) PREDICTED: neuroligin- ( 843) 4508 890.2 0 XP_011510854 (OMIM: 600568) PREDICTED: neuroligin- ( 843) 4508 890.2 0 XP_016861386 (OMIM: 600568) PREDICTED: neuroligin- ( 834) 3699 732.3 2.1e-210 XP_005247293 (OMIM: 600568) PREDICTED: neuroligin- ( 814) 3694 731.3 4.1e-210 XP_016861393 (OMIM: 600568) PREDICTED: neuroligin- ( 814) 3694 731.3 4.1e-210 XP_016861391 (OMIM: 600568) PREDICTED: neuroligin- ( 814) 3694 731.3 4.1e-210 XP_016861392 (OMIM: 600568) PREDICTED: neuroligin- ( 814) 3694 731.3 4.1e-210 XP_016861394 (OMIM: 600568) PREDICTED: neuroligin- ( 509) 3506 694.5 3.1e-199 XP_011510856 (OMIM: 600568) PREDICTED: neuroligin- ( 509) 3506 694.5 3.1e-199 XP_011510855 (OMIM: 600568) PREDICTED: neuroligin- ( 509) 3506 694.5 3.1e-199 NP_065846 (OMIM: 606479) neuroligin-2 precursor [H ( 835) 2724 542.0 4.1e-153 XP_016880386 (OMIM: 606479) PREDICTED: neuroligin- ( 656) 2185 436.8 1.5e-121 XP_005256801 (OMIM: 606479) PREDICTED: neuroligin- ( 818) 2185 436.8 1.8e-121 NP_001193779 (OMIM: 400028) neuroligin-4, Y-linked ( 648) 2133 426.6 1.7e-118 XP_016885529 (OMIM: 400028) PREDICTED: neuroligin- ( 648) 2133 426.6 1.7e-118 XP_016885528 (OMIM: 400028) PREDICTED: neuroligin- ( 691) 2133 426.6 1.8e-118 NP_851849 (OMIM: 300427,300495,300497) neuroligin- ( 816) 2134 426.9 1.8e-118 XP_016885182 (OMIM: 300427,300495,300497) PREDICTE ( 816) 2134 426.9 1.8e-118 XP_016885181 (OMIM: 300427,300495,300497) PREDICTE ( 816) 2134 426.9 1.8e-118 XP_016885180 (OMIM: 300427,300495,300497) PREDICTE ( 816) 2134 426.9 1.8e-118 NP_001269075 (OMIM: 300427,300495,300497) neurolig ( 816) 2134 426.9 1.8e-118 NP_001269074 (OMIM: 300427,300495,300497) neurolig ( 816) 2134 426.9 1.8e-118 NP_065793 (OMIM: 300427,300495,300497) neuroligin- ( 816) 2134 426.9 1.8e-118 XP_011543850 (OMIM: 300427,300495,300497) PREDICTE ( 836) 2134 426.9 1.9e-118 XP_005274623 (OMIM: 300427,300495,300497) PREDICTE ( 836) 2134 426.9 1.9e-118 XP_005274621 (OMIM: 300427,300495,300497) PREDICTE ( 836) 2134 426.9 1.9e-118 XP_011543849 (OMIM: 300427,300495,300497) PREDICTE ( 836) 2134 426.9 1.9e-118 XP_016885179 (OMIM: 300427,300495,300497) PREDICTE ( 836) 2134 426.9 1.9e-118 XP_006724567 (OMIM: 300427,300495,300497) PREDICTE ( 836) 2134 426.9 1.9e-118 XP_005274622 (OMIM: 300427,300495,300497) PREDICTE ( 836) 2134 426.9 1.9e-118 XP_016885523 (OMIM: 400028) PREDICTED: neuroligin- ( 816) 2133 426.7 2.1e-118 XP_016885527 (OMIM: 400028) PREDICTED: neuroligin- ( 816) 2133 426.7 2.1e-118 >>XP_016861387 (OMIM: 600568) PREDICTED: neuroligin-1 is (823 aa) initn: 5668 init1: 5668 opt: 5668 Z-score: 5975.2 bits: 1116.6 E(85289): 0 Smith-Waterman score: 5668; 100.0% identity (100.0% similar) in 823 aa overlap (1-823:1-823) 10 20 30 40 50 60 pF1KA1 MALPRCTWPNYVWRAVMACLVHRGLGAPLTLCMLGCLLQAGHVLSQKLDDVDPLVATNFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MALPRCTWPNYVWRAVMACLVHRGLGAPLTLCMLGCLLQAGHVLSQKLDDVDPLVATNFG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 KIRGIKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQFAPVCPQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KIRGIKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQFAPVCPQN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 IIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGPKPVMVYIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGPKPVMVYIH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 GGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRW 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 TSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTAL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 SSWAVSFQPAKYARMLATKVGCNVSDTVELVECLQKKPYKELVDQDIQPARYHIAFGPVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSWAVSFQPAKYARMLATKVGCNVSDTVELVECLQKKPYKELVDQDIQPARYHIAFGPVI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 DGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVENIVDSDDGISASDFDFAVSNFVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVENIVDSDDGISASDFDFAVSNFVD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 NLYGYPEGKDVLRETIKFMYTDWADRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLYGYPEGKDVLRETIKFMYTDWADRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 SPTYFYAFYHHCQTDQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKNDVMLSAVVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPTYFYAFYHHCQTDQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKNDVMLSAVVM 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 TYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKPRVKEHYRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKPRVKEHYRA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 NKVNLWLELVPHLHNLNDISQYTSTTTKVPSTDITFRPTRKNSVPVTSAFPTAKQDDPKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NKVNLWLELVPHLHNLNDISQYTSTTTKVPSTDITFRPTRKNSVPVTSAFPTAKQDDPKQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 QPSPFSVDQRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHDVHRRCSPQRTTTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QPSPFSVDQRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHDVHRRCSPQRTTTN 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 DLTHAQEEEIMSLQMKHTDLDHECESIHPHEVVLRTACPPDYTLAMRRSPDDVPLMTPNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLTHAQEEEIMSLQMKHTDLDHECESIHPHEVVLRTACPPDYTLAMRRSPDDVPLMTPNT 730 740 750 760 770 780 790 800 810 820 pF1KA1 ITMIPNTIPGIQPLHTFNTFTGGQNNTLPHPHPHPHSHSTTRV ::::::::::::::::::::::::::::::::::::::::::: XP_016 ITMIPNTIPGIQPLHTFNTFTGGQNNTLPHPHPHPHSHSTTRV 790 800 810 820 >>XP_016861390 (OMIM: 600568) PREDICTED: neuroligin-1 is (823 aa) initn: 5668 init1: 5668 opt: 5668 Z-score: 5975.2 bits: 1116.6 E(85289): 0 Smith-Waterman score: 5668; 100.0% identity (100.0% similar) in 823 aa overlap (1-823:1-823) 10 20 30 40 50 60 pF1KA1 MALPRCTWPNYVWRAVMACLVHRGLGAPLTLCMLGCLLQAGHVLSQKLDDVDPLVATNFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MALPRCTWPNYVWRAVMACLVHRGLGAPLTLCMLGCLLQAGHVLSQKLDDVDPLVATNFG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 KIRGIKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQFAPVCPQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KIRGIKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQFAPVCPQN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 IIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGPKPVMVYIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGPKPVMVYIH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 GGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRW 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 TSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTAL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 SSWAVSFQPAKYARMLATKVGCNVSDTVELVECLQKKPYKELVDQDIQPARYHIAFGPVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSWAVSFQPAKYARMLATKVGCNVSDTVELVECLQKKPYKELVDQDIQPARYHIAFGPVI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 DGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVENIVDSDDGISASDFDFAVSNFVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVENIVDSDDGISASDFDFAVSNFVD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 NLYGYPEGKDVLRETIKFMYTDWADRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLYGYPEGKDVLRETIKFMYTDWADRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 SPTYFYAFYHHCQTDQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKNDVMLSAVVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPTYFYAFYHHCQTDQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKNDVMLSAVVM 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 TYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKPRVKEHYRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKPRVKEHYRA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 NKVNLWLELVPHLHNLNDISQYTSTTTKVPSTDITFRPTRKNSVPVTSAFPTAKQDDPKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NKVNLWLELVPHLHNLNDISQYTSTTTKVPSTDITFRPTRKNSVPVTSAFPTAKQDDPKQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 QPSPFSVDQRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHDVHRRCSPQRTTTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QPSPFSVDQRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHDVHRRCSPQRTTTN 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 DLTHAQEEEIMSLQMKHTDLDHECESIHPHEVVLRTACPPDYTLAMRRSPDDVPLMTPNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLTHAQEEEIMSLQMKHTDLDHECESIHPHEVVLRTACPPDYTLAMRRSPDDVPLMTPNT 730 740 750 760 770 780 790 800 810 820 pF1KA1 ITMIPNTIPGIQPLHTFNTFTGGQNNTLPHPHPHPHSHSTTRV ::::::::::::::::::::::::::::::::::::::::::: XP_016 ITMIPNTIPGIQPLHTFNTFTGGQNNTLPHPHPHPHSHSTTRV 790 800 810 820 >>XP_016861388 (OMIM: 600568) PREDICTED: neuroligin-1 is (823 aa) initn: 5668 init1: 5668 opt: 5668 Z-score: 5975.2 bits: 1116.6 E(85289): 0 Smith-Waterman score: 5668; 100.0% identity (100.0% similar) in 823 aa overlap (1-823:1-823) 10 20 30 40 50 60 pF1KA1 MALPRCTWPNYVWRAVMACLVHRGLGAPLTLCMLGCLLQAGHVLSQKLDDVDPLVATNFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MALPRCTWPNYVWRAVMACLVHRGLGAPLTLCMLGCLLQAGHVLSQKLDDVDPLVATNFG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 KIRGIKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQFAPVCPQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KIRGIKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQFAPVCPQN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 IIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGPKPVMVYIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGPKPVMVYIH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 GGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRW 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 TSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTAL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 SSWAVSFQPAKYARMLATKVGCNVSDTVELVECLQKKPYKELVDQDIQPARYHIAFGPVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSWAVSFQPAKYARMLATKVGCNVSDTVELVECLQKKPYKELVDQDIQPARYHIAFGPVI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 DGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVENIVDSDDGISASDFDFAVSNFVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVENIVDSDDGISASDFDFAVSNFVD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 NLYGYPEGKDVLRETIKFMYTDWADRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLYGYPEGKDVLRETIKFMYTDWADRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 SPTYFYAFYHHCQTDQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKNDVMLSAVVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPTYFYAFYHHCQTDQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKNDVMLSAVVM 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 TYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKPRVKEHYRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKPRVKEHYRA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 NKVNLWLELVPHLHNLNDISQYTSTTTKVPSTDITFRPTRKNSVPVTSAFPTAKQDDPKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NKVNLWLELVPHLHNLNDISQYTSTTTKVPSTDITFRPTRKNSVPVTSAFPTAKQDDPKQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 QPSPFSVDQRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHDVHRRCSPQRTTTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QPSPFSVDQRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHDVHRRCSPQRTTTN 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 DLTHAQEEEIMSLQMKHTDLDHECESIHPHEVVLRTACPPDYTLAMRRSPDDVPLMTPNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLTHAQEEEIMSLQMKHTDLDHECESIHPHEVVLRTACPPDYTLAMRRSPDDVPLMTPNT 730 740 750 760 770 780 790 800 810 820 pF1KA1 ITMIPNTIPGIQPLHTFNTFTGGQNNTLPHPHPHPHSHSTTRV ::::::::::::::::::::::::::::::::::::::::::: XP_016 ITMIPNTIPGIQPLHTFNTFTGGQNNTLPHPHPHPHSHSTTRV 790 800 810 820 >>NP_055747 (OMIM: 600568) neuroligin-1 [Homo sapiens] (823 aa) initn: 5668 init1: 5668 opt: 5668 Z-score: 5975.2 bits: 1116.6 E(85289): 0 Smith-Waterman score: 5668; 100.0% identity (100.0% similar) in 823 aa overlap (1-823:1-823) 10 20 30 40 50 60 pF1KA1 MALPRCTWPNYVWRAVMACLVHRGLGAPLTLCMLGCLLQAGHVLSQKLDDVDPLVATNFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MALPRCTWPNYVWRAVMACLVHRGLGAPLTLCMLGCLLQAGHVLSQKLDDVDPLVATNFG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 KIRGIKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQFAPVCPQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KIRGIKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQFAPVCPQN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 IIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGPKPVMVYIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 IIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGPKPVMVYIH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 GGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRW 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 TSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTAL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 SSWAVSFQPAKYARMLATKVGCNVSDTVELVECLQKKPYKELVDQDIQPARYHIAFGPVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SSWAVSFQPAKYARMLATKVGCNVSDTVELVECLQKKPYKELVDQDIQPARYHIAFGPVI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 DGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVENIVDSDDGISASDFDFAVSNFVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 DGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVENIVDSDDGISASDFDFAVSNFVD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 NLYGYPEGKDVLRETIKFMYTDWADRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 NLYGYPEGKDVLRETIKFMYTDWADRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 SPTYFYAFYHHCQTDQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKNDVMLSAVVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SPTYFYAFYHHCQTDQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKNDVMLSAVVM 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 TYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKPRVKEHYRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKPRVKEHYRA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 NKVNLWLELVPHLHNLNDISQYTSTTTKVPSTDITFRPTRKNSVPVTSAFPTAKQDDPKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 NKVNLWLELVPHLHNLNDISQYTSTTTKVPSTDITFRPTRKNSVPVTSAFPTAKQDDPKQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 QPSPFSVDQRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHDVHRRCSPQRTTTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 QPSPFSVDQRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHDVHRRCSPQRTTTN 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 DLTHAQEEEIMSLQMKHTDLDHECESIHPHEVVLRTACPPDYTLAMRRSPDDVPLMTPNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 DLTHAQEEEIMSLQMKHTDLDHECESIHPHEVVLRTACPPDYTLAMRRSPDDVPLMTPNT 730 740 750 760 770 780 790 800 810 820 pF1KA1 ITMIPNTIPGIQPLHTFNTFTGGQNNTLPHPHPHPHSHSTTRV ::::::::::::::::::::::::::::::::::::::::::: NP_055 ITMIPNTIPGIQPLHTFNTFTGGQNNTLPHPHPHPHSHSTTRV 790 800 810 820 >>XP_016861389 (OMIM: 600568) PREDICTED: neuroligin-1 is (823 aa) initn: 5668 init1: 5668 opt: 5668 Z-score: 5975.2 bits: 1116.6 E(85289): 0 Smith-Waterman score: 5668; 100.0% identity (100.0% similar) in 823 aa overlap (1-823:1-823) 10 20 30 40 50 60 pF1KA1 MALPRCTWPNYVWRAVMACLVHRGLGAPLTLCMLGCLLQAGHVLSQKLDDVDPLVATNFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MALPRCTWPNYVWRAVMACLVHRGLGAPLTLCMLGCLLQAGHVLSQKLDDVDPLVATNFG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 KIRGIKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQFAPVCPQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KIRGIKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQFAPVCPQN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 IIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGPKPVMVYIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGPKPVMVYIH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 GGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRW 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 TSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTAL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 SSWAVSFQPAKYARMLATKVGCNVSDTVELVECLQKKPYKELVDQDIQPARYHIAFGPVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSWAVSFQPAKYARMLATKVGCNVSDTVELVECLQKKPYKELVDQDIQPARYHIAFGPVI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 DGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVENIVDSDDGISASDFDFAVSNFVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVENIVDSDDGISASDFDFAVSNFVD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 NLYGYPEGKDVLRETIKFMYTDWADRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLYGYPEGKDVLRETIKFMYTDWADRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 SPTYFYAFYHHCQTDQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKNDVMLSAVVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPTYFYAFYHHCQTDQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKNDVMLSAVVM 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 TYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKPRVKEHYRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKPRVKEHYRA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 NKVNLWLELVPHLHNLNDISQYTSTTTKVPSTDITFRPTRKNSVPVTSAFPTAKQDDPKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NKVNLWLELVPHLHNLNDISQYTSTTTKVPSTDITFRPTRKNSVPVTSAFPTAKQDDPKQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 QPSPFSVDQRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHDVHRRCSPQRTTTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QPSPFSVDQRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHDVHRRCSPQRTTTN 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 DLTHAQEEEIMSLQMKHTDLDHECESIHPHEVVLRTACPPDYTLAMRRSPDDVPLMTPNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLTHAQEEEIMSLQMKHTDLDHECESIHPHEVVLRTACPPDYTLAMRRSPDDVPLMTPNT 730 740 750 760 770 780 790 800 810 820 pF1KA1 ITMIPNTIPGIQPLHTFNTFTGGQNNTLPHPHPHPHSHSTTRV ::::::::::::::::::::::::::::::::::::::::::: XP_016 ITMIPNTIPGIQPLHTFNTFTGGQNNTLPHPHPHPHSHSTTRV 790 800 810 820 >>XP_005247292 (OMIM: 600568) PREDICTED: neuroligin-1 is (823 aa) initn: 5668 init1: 5668 opt: 5668 Z-score: 5975.2 bits: 1116.6 E(85289): 0 Smith-Waterman score: 5668; 100.0% identity (100.0% similar) in 823 aa overlap (1-823:1-823) 10 20 30 40 50 60 pF1KA1 MALPRCTWPNYVWRAVMACLVHRGLGAPLTLCMLGCLLQAGHVLSQKLDDVDPLVATNFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MALPRCTWPNYVWRAVMACLVHRGLGAPLTLCMLGCLLQAGHVLSQKLDDVDPLVATNFG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 KIRGIKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQFAPVCPQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KIRGIKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQFAPVCPQN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 IIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGPKPVMVYIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGPKPVMVYIH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 GGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRW 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 TSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTAL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 SSWAVSFQPAKYARMLATKVGCNVSDTVELVECLQKKPYKELVDQDIQPARYHIAFGPVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSWAVSFQPAKYARMLATKVGCNVSDTVELVECLQKKPYKELVDQDIQPARYHIAFGPVI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 DGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVENIVDSDDGISASDFDFAVSNFVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVENIVDSDDGISASDFDFAVSNFVD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 NLYGYPEGKDVLRETIKFMYTDWADRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NLYGYPEGKDVLRETIKFMYTDWADRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 SPTYFYAFYHHCQTDQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKNDVMLSAVVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SPTYFYAFYHHCQTDQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKNDVMLSAVVM 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 TYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKPRVKEHYRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKPRVKEHYRA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 NKVNLWLELVPHLHNLNDISQYTSTTTKVPSTDITFRPTRKNSVPVTSAFPTAKQDDPKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NKVNLWLELVPHLHNLNDISQYTSTTTKVPSTDITFRPTRKNSVPVTSAFPTAKQDDPKQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 QPSPFSVDQRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHDVHRRCSPQRTTTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QPSPFSVDQRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHDVHRRCSPQRTTTN 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 DLTHAQEEEIMSLQMKHTDLDHECESIHPHEVVLRTACPPDYTLAMRRSPDDVPLMTPNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DLTHAQEEEIMSLQMKHTDLDHECESIHPHEVVLRTACPPDYTLAMRRSPDDVPLMTPNT 730 740 750 760 770 780 790 800 810 820 pF1KA1 ITMIPNTIPGIQPLHTFNTFTGGQNNTLPHPHPHPHSHSTTRV ::::::::::::::::::::::::::::::::::::::::::: XP_005 ITMIPNTIPGIQPLHTFNTFTGGQNNTLPHPHPHPHSHSTTRV 790 800 810 820 >>XP_005247291 (OMIM: 600568) PREDICTED: neuroligin-1 is (823 aa) initn: 5668 init1: 5668 opt: 5668 Z-score: 5975.2 bits: 1116.6 E(85289): 0 Smith-Waterman score: 5668; 100.0% identity (100.0% similar) in 823 aa overlap (1-823:1-823) 10 20 30 40 50 60 pF1KA1 MALPRCTWPNYVWRAVMACLVHRGLGAPLTLCMLGCLLQAGHVLSQKLDDVDPLVATNFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MALPRCTWPNYVWRAVMACLVHRGLGAPLTLCMLGCLLQAGHVLSQKLDDVDPLVATNFG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 KIRGIKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQFAPVCPQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KIRGIKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQFAPVCPQN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 IIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGPKPVMVYIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGPKPVMVYIH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 GGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRW 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 TSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTAL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 SSWAVSFQPAKYARMLATKVGCNVSDTVELVECLQKKPYKELVDQDIQPARYHIAFGPVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSWAVSFQPAKYARMLATKVGCNVSDTVELVECLQKKPYKELVDQDIQPARYHIAFGPVI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 DGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVENIVDSDDGISASDFDFAVSNFVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVENIVDSDDGISASDFDFAVSNFVD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 NLYGYPEGKDVLRETIKFMYTDWADRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NLYGYPEGKDVLRETIKFMYTDWADRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 SPTYFYAFYHHCQTDQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKNDVMLSAVVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SPTYFYAFYHHCQTDQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKNDVMLSAVVM 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 TYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKPRVKEHYRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKPRVKEHYRA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 NKVNLWLELVPHLHNLNDISQYTSTTTKVPSTDITFRPTRKNSVPVTSAFPTAKQDDPKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NKVNLWLELVPHLHNLNDISQYTSTTTKVPSTDITFRPTRKNSVPVTSAFPTAKQDDPKQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 QPSPFSVDQRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHDVHRRCSPQRTTTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QPSPFSVDQRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHDVHRRCSPQRTTTN 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 DLTHAQEEEIMSLQMKHTDLDHECESIHPHEVVLRTACPPDYTLAMRRSPDDVPLMTPNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DLTHAQEEEIMSLQMKHTDLDHECESIHPHEVVLRTACPPDYTLAMRRSPDDVPLMTPNT 730 740 750 760 770 780 790 800 810 820 pF1KA1 ITMIPNTIPGIQPLHTFNTFTGGQNNTLPHPHPHPHSHSTTRV ::::::::::::::::::::::::::::::::::::::::::: XP_005 ITMIPNTIPGIQPLHTFNTFTGGQNNTLPHPHPHPHSHSTTRV 790 800 810 820 >>XP_005247294 (OMIM: 600568) PREDICTED: neuroligin-1 is (671 aa) initn: 4515 init1: 4515 opt: 4515 Z-score: 4760.4 bits: 891.5 E(85289): 0 Smith-Waterman score: 4515; 99.2% identity (99.5% similar) in 666 aa overlap (158-823:6-671) 130 140 150 160 170 180 pF1KA1 EVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGPKPVMVYIHGGSYMEG .:: . ::::::::::::::::::::::: XP_005 MCWGFLYVLCQKDIRDSGGPKPVMVYIHGGSYMEG 10 20 30 190 200 210 220 230 240 pF1KA1 TGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRWTSENIGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRWTSENIGF 40 50 60 70 80 90 250 260 270 280 290 300 pF1KA1 FGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSF 100 110 120 130 140 150 310 320 330 340 350 360 pF1KA1 QPAKYARMLATKVGCNVSDTVELVECLQKKPYKELVDQDIQPARYHIAFGPVIDGDVIPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QPAKYARMLATKVGCNVSDTVELVECLQKKPYKELVDQDIQPARYHIAFGPVIDGDVIPD 160 170 180 190 200 210 370 380 390 400 410 420 pF1KA1 DPQILMEQGEFLNYDIMLGVNQGEGLKFVENIVDSDDGISASDFDFAVSNFVDNLYGYPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DPQILMEQGEFLNYDIMLGVNQGEGLKFVENIVDSDDGISASDFDFAVSNFVDNLYGYPE 220 230 240 250 260 270 430 440 450 460 470 480 pF1KA1 GKDVLRETIKFMYTDWADRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFGSPTYFYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GKDVLRETIKFMYTDWADRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFGSPTYFYA 280 290 300 310 320 330 490 500 510 520 530 540 pF1KA1 FYHHCQTDQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKNDVMLSAVVMTYWTNFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FYHHCQTDQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKNDVMLSAVVMTYWTNFA 340 350 360 370 380 390 550 560 570 580 590 600 pF1KA1 KTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKPRVKEHYRANKVNLWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKPRVKEHYRANKVNLWL 400 410 420 430 440 450 610 620 630 640 650 660 pF1KA1 ELVPHLHNLNDISQYTSTTTKVPSTDITFRPTRKNSVPVTSAFPTAKQDDPKQQPSPFSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ELVPHLHNLNDISQYTSTTTKVPSTDITFRPTRKNSVPVTSAFPTAKQDDPKQQPSPFSV 460 470 480 490 500 510 670 680 690 700 710 720 pF1KA1 DQRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHDVHRRCSPQRTTTNDLTHAQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DQRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHDVHRRCSPQRTTTNDLTHAQE 520 530 540 550 560 570 730 740 750 760 770 780 pF1KA1 EEIMSLQMKHTDLDHECESIHPHEVVLRTACPPDYTLAMRRSPDDVPLMTPNTITMIPNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EEIMSLQMKHTDLDHECESIHPHEVVLRTACPPDYTLAMRRSPDDVPLMTPNTITMIPNT 580 590 600 610 620 630 790 800 810 820 pF1KA1 IPGIQPLHTFNTFTGGQNNTLPHPHPHPHSHSTTRV :::::::::::::::::::::::::::::::::::: XP_005 IPGIQPLHTFNTFTGGQNNTLPHPHPHPHSHSTTRV 640 650 660 670 >>XP_016861381 (OMIM: 600568) PREDICTED: neuroligin-1 is (843 aa) initn: 4504 init1: 4504 opt: 4509 Z-score: 4752.6 bits: 890.4 E(85289): 0 Smith-Waterman score: 5618; 97.6% identity (97.6% similar) in 843 aa overlap (1-823:1-843) 10 20 30 40 50 60 pF1KA1 MALPRCTWPNYVWRAVMACLVHRGLGAPLTLCMLGCLLQAGHVLSQKLDDVDPLVATNFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MALPRCTWPNYVWRAVMACLVHRGLGAPLTLCMLGCLLQAGHVLSQKLDDVDPLVATNFG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 KIRGIKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQFAPVCPQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KIRGIKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQFAPVCPQN 70 80 90 100 110 120 130 140 150 160 pF1KA1 IIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTED---------------- :::::::::::::::::::::::::::::::::::::::::::: XP_016 IIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDVKRISKECARKPGKKI 130 140 150 160 170 180 170 180 190 200 210 220 pF1KA1 ----DIRDSGGPKPVMVYIHGGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLST :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CRKGDIRDSGGPKPVMVYIHGGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLST 190 200 210 220 230 240 230 240 250 260 270 280 pF1KA1 GDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNR 250 260 270 280 290 300 290 300 310 320 330 340 pF1KA1 WSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARMLATKVGCNVSDTVELVECLQKKPYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARMLATKVGCNVSDTVELVECLQKKPYK 310 320 330 340 350 360 350 360 370 380 390 400 pF1KA1 ELVDQDIQPARYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVENIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELVDQDIQPARYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVENIV 370 380 390 400 410 420 410 420 430 440 450 460 pF1KA1 DSDDGISASDFDFAVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRHNPETRRKTLLALF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DSDDGISASDFDFAVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRHNPETRRKTLLALF 430 440 450 460 470 480 470 480 490 500 510 520 pF1KA1 TDHQWVAPAVATADLHSNFGSPTYFYAFYHHCQTDQVPAWADAAHGDEVPYVLGIPMIGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TDHQWVAPAVATADLHSNFGSPTYFYAFYHHCQTDQVPAWADAAHGDEVPYVLGIPMIGP 490 500 510 520 530 540 530 540 550 560 570 580 pF1KA1 TELFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TELFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQ 550 560 570 580 590 600 590 600 610 620 630 640 pF1KA1 KDQLYLHIGLKPRVKEHYRANKVNLWLELVPHLHNLNDISQYTSTTTKVPSTDITFRPTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KDQLYLHIGLKPRVKEHYRANKVNLWLELVPHLHNLNDISQYTSTTTKVPSTDITFRPTR 610 620 630 640 650 660 650 660 670 680 690 700 pF1KA1 KNSVPVTSAFPTAKQDDPKQQPSPFSVDQRDYSTELSVTIAVGASLLFLNILAFAALYYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KNSVPVTSAFPTAKQDDPKQQPSPFSVDQRDYSTELSVTIAVGASLLFLNILAFAALYYK 670 680 690 700 710 720 710 720 730 740 750 760 pF1KA1 KDKRRHDVHRRCSPQRTTTNDLTHAQEEEIMSLQMKHTDLDHECESIHPHEVVLRTACPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KDKRRHDVHRRCSPQRTTTNDLTHAQEEEIMSLQMKHTDLDHECESIHPHEVVLRTACPP 730 740 750 760 770 780 770 780 790 800 810 820 pF1KA1 DYTLAMRRSPDDVPLMTPNTITMIPNTIPGIQPLHTFNTFTGGQNNTLPHPHPHPHSHST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DYTLAMRRSPDDVPLMTPNTITMIPNTIPGIQPLHTFNTFTGGQNNTLPHPHPHPHSHST 790 800 810 820 830 840 pF1KA1 TRV ::: XP_016 TRV >>XP_016861378 (OMIM: 600568) PREDICTED: neuroligin-1 is (843 aa) initn: 4504 init1: 4504 opt: 4509 Z-score: 4752.6 bits: 890.4 E(85289): 0 Smith-Waterman score: 5618; 97.6% identity (97.6% similar) in 843 aa overlap (1-823:1-843) 10 20 30 40 50 60 pF1KA1 MALPRCTWPNYVWRAVMACLVHRGLGAPLTLCMLGCLLQAGHVLSQKLDDVDPLVATNFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MALPRCTWPNYVWRAVMACLVHRGLGAPLTLCMLGCLLQAGHVLSQKLDDVDPLVATNFG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 KIRGIKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQFAPVCPQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KIRGIKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQFAPVCPQN 70 80 90 100 110 120 130 140 150 160 pF1KA1 IIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTED---------------- :::::::::::::::::::::::::::::::::::::::::::: XP_016 IIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDVKRISKECARKPGKKI 130 140 150 160 170 180 170 180 190 200 210 220 pF1KA1 ----DIRDSGGPKPVMVYIHGGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLST :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CRKGDIRDSGGPKPVMVYIHGGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLST 190 200 210 220 230 240 230 240 250 260 270 280 pF1KA1 GDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNR 250 260 270 280 290 300 290 300 310 320 330 340 pF1KA1 WSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARMLATKVGCNVSDTVELVECLQKKPYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARMLATKVGCNVSDTVELVECLQKKPYK 310 320 330 340 350 360 350 360 370 380 390 400 pF1KA1 ELVDQDIQPARYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVENIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELVDQDIQPARYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVENIV 370 380 390 400 410 420 410 420 430 440 450 460 pF1KA1 DSDDGISASDFDFAVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRHNPETRRKTLLALF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DSDDGISASDFDFAVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRHNPETRRKTLLALF 430 440 450 460 470 480 470 480 490 500 510 520 pF1KA1 TDHQWVAPAVATADLHSNFGSPTYFYAFYHHCQTDQVPAWADAAHGDEVPYVLGIPMIGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TDHQWVAPAVATADLHSNFGSPTYFYAFYHHCQTDQVPAWADAAHGDEVPYVLGIPMIGP 490 500 510 520 530 540 530 540 550 560 570 580 pF1KA1 TELFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TELFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQ 550 560 570 580 590 600 590 600 610 620 630 640 pF1KA1 KDQLYLHIGLKPRVKEHYRANKVNLWLELVPHLHNLNDISQYTSTTTKVPSTDITFRPTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KDQLYLHIGLKPRVKEHYRANKVNLWLELVPHLHNLNDISQYTSTTTKVPSTDITFRPTR 610 620 630 640 650 660 650 660 670 680 690 700 pF1KA1 KNSVPVTSAFPTAKQDDPKQQPSPFSVDQRDYSTELSVTIAVGASLLFLNILAFAALYYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KNSVPVTSAFPTAKQDDPKQQPSPFSVDQRDYSTELSVTIAVGASLLFLNILAFAALYYK 670 680 690 700 710 720 710 720 730 740 750 760 pF1KA1 KDKRRHDVHRRCSPQRTTTNDLTHAQEEEIMSLQMKHTDLDHECESIHPHEVVLRTACPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KDKRRHDVHRRCSPQRTTTNDLTHAQEEEIMSLQMKHTDLDHECESIHPHEVVLRTACPP 730 740 750 760 770 780 770 780 790 800 810 820 pF1KA1 DYTLAMRRSPDDVPLMTPNTITMIPNTIPGIQPLHTFNTFTGGQNNTLPHPHPHPHSHST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DYTLAMRRSPDDVPLMTPNTITMIPNTIPGIQPLHTFNTFTGGQNNTLPHPHPHPHSHST 790 800 810 820 830 840 pF1KA1 TRV ::: XP_016 TRV 823 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 20:22:03 2016 done: Wed Nov 2 20:22:04 2016 Total Scan time: 11.960 Total Display time: 0.290 Function used was FASTA [36.3.4 Apr, 2011]