Result of FASTA (omim) for
pF1KA1081
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA1081, 992 aa
1>>>pF1KA1081 992 - 992 aa - 992 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 13.6192+/-0.000689; mu= -14.2603+/- 0.043
mean_var=750.3160+/-155.688, 0's: 0 Z-trim(118.2): 521 B-trim: 0 in 0/58
Lambda= 0.046822
statistics sampled from 30337 (30893) to 30337 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.652), E-opt: 0.2 (0.362), width: 16
Scan time: 15.360
The best scores are: opt bits E(85289)
XP_016874555 (OMIM: 607127) PREDICTED: ELKS/Rab6-i (1092) 6115 429.9 3.5e-119
NP_829883 (OMIM: 607127) ELKS/Rab6-interacting/CAS (1088) 6077 427.4 2.1e-118
XP_016874556 (OMIM: 607127) PREDICTED: ELKS/Rab6-i (1088) 6077 427.4 2.1e-118
XP_016874554 (OMIM: 607127) PREDICTED: ELKS/Rab6-i (1110) 5326 376.7 3.9e-103
XP_016874560 (OMIM: 607127) PREDICTED: ELKS/Rab6-i (1048) 5108 361.9 1e-98
XP_016874551 (OMIM: 607127) PREDICTED: ELKS/Rab6-i (1120) 3396 246.3 6.9e-64
XP_016874550 (OMIM: 607127) PREDICTED: ELKS/Rab6-i (1123) 3376 244.9 1.8e-63
XP_016874549 (OMIM: 607127) PREDICTED: ELKS/Rab6-i (1134) 3142 229.1 1e-58
NP_001288177 (OMIM: 607127) ELKS/Rab6-interacting/ (1086) 3122 227.8 2.5e-58
XP_016874557 (OMIM: 607127) PREDICTED: ELKS/Rab6-i (1086) 3122 227.8 2.5e-58
XP_016874553 (OMIM: 607127) PREDICTED: ELKS/Rab6-i (1116) 3122 227.8 2.6e-58
NP_829884 (OMIM: 607127) ELKS/Rab6-interacting/CAS (1116) 3122 227.8 2.6e-58
XP_011519243 (OMIM: 607127) PREDICTED: ELKS/Rab6-i (1116) 3122 227.8 2.6e-58
XP_016874552 (OMIM: 607127) PREDICTED: ELKS/Rab6-i (1119) 3092 225.8 1e-57
XP_016874547 (OMIM: 607127) PREDICTED: ELKS/Rab6-i (1138) 3089 225.6 1.2e-57
XP_016874546 (OMIM: 607127) PREDICTED: ELKS/Rab6-i (1138) 3089 225.6 1.2e-57
XP_016874559 (OMIM: 607127) PREDICTED: ELKS/Rab6-i (1072) 3087 225.4 1.3e-57
XP_016874558 (OMIM: 607127) PREDICTED: ELKS/Rab6-i (1079) 3082 225.1 1.6e-57
XP_016874561 (OMIM: 607127) PREDICTED: ELKS/Rab6-i (1041) 3065 223.9 3.5e-57
XP_016874542 (OMIM: 607127) PREDICTED: ELKS/Rab6-i (1141) 3065 223.9 3.7e-57
XP_016874543 (OMIM: 607127) PREDICTED: ELKS/Rab6-i (1141) 3065 223.9 3.7e-57
XP_016874541 (OMIM: 607127) PREDICTED: ELKS/Rab6-i (1141) 3065 223.9 3.7e-57
XP_016874544 (OMIM: 607127) PREDICTED: ELKS/Rab6-i (1141) 3065 223.9 3.7e-57
XP_016874545 (OMIM: 607127) PREDICTED: ELKS/Rab6-i (1141) 3065 223.9 3.7e-57
XP_016874548 (OMIM: 607127) PREDICTED: ELKS/Rab6-i (1137) 3061 223.7 4.5e-57
XP_016874562 (OMIM: 607127) PREDICTED: ELKS/Rab6-i ( 975) 3055 223.2 5.4e-57
XP_016874564 (OMIM: 607127) PREDICTED: ELKS/Rab6-i ( 527) 2549 188.7 7.1e-47
XP_016874563 (OMIM: 607127) PREDICTED: ELKS/Rab6-i ( 545) 1760 135.4 8e-31
XP_016883108 (OMIM: 609689) PREDICTED: centrosome- (1976) 466 48.7 0.00038
NP_001305148 (OMIM: 609689) centrosome-associated (1810) 455 47.9 0.00059
XP_011536094 (OMIM: 605629,617090) PREDICTED: citr (1545) 424 45.7 0.0023
XP_016874228 (OMIM: 605629,617090) PREDICTED: citr (1545) 424 45.7 0.0023
XP_011536090 (OMIM: 605629,617090) PREDICTED: citr (2011) 424 45.8 0.0027
XP_011536089 (OMIM: 605629,617090) PREDICTED: citr (2012) 424 45.8 0.0027
NP_057279 (OMIM: 605498) kinesin-like protein KIF2 (1780) 421 45.6 0.0029
XP_006720202 (OMIM: 600381) PREDICTED: kinectin is (1329) 417 45.1 0.0029
NP_001257943 (OMIM: 600381) kinectin isoform d [Ho (1329) 417 45.1 0.0029
NP_001271188 (OMIM: 605498) kinesin-like protein K (1820) 421 45.6 0.0029
XP_011535053 (OMIM: 600381) PREDICTED: kinectin is (1357) 413 44.9 0.0035
XP_016876767 (OMIM: 600381) PREDICTED: kinectin is (1357) 413 44.9 0.0035
NP_001072989 (OMIM: 600381) kinectin isoform a [Ho (1357) 413 44.9 0.0035
XP_006720201 (OMIM: 600381) PREDICTED: kinectin is (1357) 413 44.9 0.0035
XP_016874227 (OMIM: 605629,617090) PREDICTED: citr (1576) 408 44.6 0.0049
XP_011535055 (OMIM: 600381) PREDICTED: kinectin is (1306) 404 44.3 0.0053
NP_001072990 (OMIM: 600381) kinectin isoform b [Ho (1306) 404 44.3 0.0053
NP_003793 (OMIM: 603487) myosin-13 [Homo sapiens] (1938) 408 44.7 0.0056
NP_009105 (OMIM: 605629,617090) citron Rho-interac (2027) 408 44.8 0.0058
XP_016858403 (OMIM: 615776) PREDICTED: rootletin i (1894) 406 44.6 0.0061
XP_011535054 (OMIM: 600381) PREDICTED: kinectin is (1334) 400 44.0 0.0064
XP_006720204 (OMIM: 600381) PREDICTED: kinectin is (1298) 397 43.8 0.0073
>>XP_016874555 (OMIM: 607127) PREDICTED: ELKS/Rab6-inter (1092 aa)
initn: 6115 init1: 6115 opt: 6115 Z-score: 2260.8 bits: 429.9 E(85289): 3.5e-119
Smith-Waterman score: 6115; 100.0% identity (100.0% similar) in 984 aa overlap (1-984:1-984)
10 20 30 40 50 60
pF1KA1 MYGSARSVGKVEPSSQSPGRSPRLPRSPRLGHRRTNSTGGSSGSSVGGGSGKTLSMENIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MYGSARSVGKVEPSSQSPGRSPRLPRSPRLGHRRTNSTGGSSGSSVGGGSGKTLSMENIQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 SLNAAYATSGPMYLSDHENVGSETPKSTMTLGRSGGRLPYGVRMTAMGSSPNIASSGVAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLNAAYATSGPMYLSDHENVGSETPKSTMTLGRSGGRLPYGVRMTAMGSSPNIASSGVAS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 DTIAFGEHHLPPVSMASTVPHSLRQARDNTIMDLQTQLKEVLRENDLLRKDVEVKESKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTIAFGEHHLPPVSMASTVPHSLRQARDNTIMDLQTQLKEVLRENDLLRKDVEVKESKLS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 SSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQDELRIQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQDELRIQR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 DLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 TLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSML
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 REEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEERE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEERE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 EEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 SLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 KERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERT
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 IERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 GLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 DESSKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTSRQVKDQNKKVANLKHKEQVEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DESSKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTSRQVKDQNKKVANLKHKEQVEK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA1 KKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEE
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA1 SARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA1 EMKQEALLAAISEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKLMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EMKQEALLAAISEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKLMA
910 920 930 940 950 960
970 980 990
pF1KA1 DNYEDDHFKSSHSNQTNHKPSPDQDEEEGIWA
::::::::::::::::::::::::
XP_016 DNYEDDHFKSSHSNQTNHKPSPDQIIQPLLELDQNRSKLKLYIGHLTTLCHDRDPLILRG
970 980 990 1000 1010 1020
>>NP_829883 (OMIM: 607127) ELKS/Rab6-interacting/CAST fa (1088 aa)
initn: 4720 init1: 4720 opt: 6077 Z-score: 2246.9 bits: 427.4 E(85289): 2.1e-118
Smith-Waterman score: 6077; 99.6% identity (99.6% similar) in 984 aa overlap (1-984:1-980)
10 20 30 40 50 60
pF1KA1 MYGSARSVGKVEPSSQSPGRSPRLPRSPRLGHRRTNSTGGSSGSSVGGGSGKTLSMENIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_829 MYGSARSVGKVEPSSQSPGRSPRLPRSPRLGHRRTNSTGGSSGSSVGGGSGKTLSMENIQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 SLNAAYATSGPMYLSDHENVGSETPKSTMTLGRSGGRLPYGVRMTAMGSSPNIASSGVAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_829 SLNAAYATSGPMYLSDHENVGSETPKSTMTLGRSGGRLPYGVRMTAMGSSPNIASSGVAS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 DTIAFGEHHLPPVSMASTVPHSLRQARDNTIMDLQTQLKEVLRENDLLRKDVEVKESKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_829 DTIAFGEHHLPPVSMASTVPHSLRQARDNTIMDLQTQLKEVLRENDLLRKDVEVKESKLS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 SSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQDELRIQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_829 SSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQDELRIQR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 DLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_829 DLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 TLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_829 TLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSML
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 REEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEERE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_829 REEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEERE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 EEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_829 EEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 SLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_829 SLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 KERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_829 KERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERT
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 IERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_829 IERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 GLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_829 GLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 DESSKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTSRQVKDQNKKVANLKHKEQVEK
::::::::::::::::::::::::::::::::::: :::::::::::::::::::::
NP_829 DESSKAQAEVDRLLEILKEVENEKNDKDKKIAELE----RQVKDQNKKVANLKHKEQVEK
730 740 750 760 770
790 800 810 820 830 840
pF1KA1 KKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_829 KKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEE
780 790 800 810 820 830
850 860 870 880 890 900
pF1KA1 SARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_829 SARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVL
840 850 860 870 880 890
910 920 930 940 950 960
pF1KA1 EMKQEALLAAISEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKLMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_829 EMKQEALLAAISEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKLMA
900 910 920 930 940 950
970 980 990
pF1KA1 DNYEDDHFKSSHSNQTNHKPSPDQDEEEGIWA
::::::::::::::::::::::::
NP_829 DNYEDDHFKSSHSNQTNHKPSPDQIIQPLLELDQNRSKLKLYIGHLTTLCHDRDPLILRG
960 970 980 990 1000 1010
>>XP_016874556 (OMIM: 607127) PREDICTED: ELKS/Rab6-inter (1088 aa)
initn: 4720 init1: 4720 opt: 6077 Z-score: 2246.9 bits: 427.4 E(85289): 2.1e-118
Smith-Waterman score: 6077; 99.6% identity (99.6% similar) in 984 aa overlap (1-984:1-980)
10 20 30 40 50 60
pF1KA1 MYGSARSVGKVEPSSQSPGRSPRLPRSPRLGHRRTNSTGGSSGSSVGGGSGKTLSMENIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MYGSARSVGKVEPSSQSPGRSPRLPRSPRLGHRRTNSTGGSSGSSVGGGSGKTLSMENIQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 SLNAAYATSGPMYLSDHENVGSETPKSTMTLGRSGGRLPYGVRMTAMGSSPNIASSGVAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLNAAYATSGPMYLSDHENVGSETPKSTMTLGRSGGRLPYGVRMTAMGSSPNIASSGVAS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 DTIAFGEHHLPPVSMASTVPHSLRQARDNTIMDLQTQLKEVLRENDLLRKDVEVKESKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTIAFGEHHLPPVSMASTVPHSLRQARDNTIMDLQTQLKEVLRENDLLRKDVEVKESKLS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 SSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQDELRIQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQDELRIQR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 DLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 TLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSML
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 REEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEERE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEERE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 EEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 SLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 KERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERT
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 IERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 GLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 DESSKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTSRQVKDQNKKVANLKHKEQVEK
::::::::::::::::::::::::::::::::::: :::::::::::::::::::::
XP_016 DESSKAQAEVDRLLEILKEVENEKNDKDKKIAELE----RQVKDQNKKVANLKHKEQVEK
730 740 750 760 770
790 800 810 820 830 840
pF1KA1 KKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEE
780 790 800 810 820 830
850 860 870 880 890 900
pF1KA1 SARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVL
840 850 860 870 880 890
910 920 930 940 950 960
pF1KA1 EMKQEALLAAISEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKLMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EMKQEALLAAISEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKLMA
900 910 920 930 940 950
970 980 990
pF1KA1 DNYEDDHFKSSHSNQTNHKPSPDQDEEEGIWA
::::::::::::::::::::::::
XP_016 DNYEDDHFKSSHSNQTNHKPSPDQIIQPLLELDQNRSKLKLYIGHLTTLCHDRDPLILRG
960 970 980 990 1000 1010
>>XP_016874554 (OMIM: 607127) PREDICTED: ELKS/Rab6-inter (1110 aa)
initn: 5395 init1: 5287 opt: 5326 Z-score: 1972.6 bits: 376.7 E(85289): 3.9e-103
Smith-Waterman score: 6069; 98.2% identity (98.2% similar) in 1002 aa overlap (1-984:1-1002)
10 20 30 40 50 60
pF1KA1 MYGSARSVGKVEPSSQSPGRSPRLPRSPRLGHRRTNSTGGSSGSSVGGGSGKTLSMENIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MYGSARSVGKVEPSSQSPGRSPRLPRSPRLGHRRTNSTGGSSGSSVGGGSGKTLSMENIQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 SLNAAYATSGPMYLSDHENVGSETPKSTMTLGRSGGRLPYGVRMTAMGSSPNIASSGVAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLNAAYATSGPMYLSDHENVGSETPKSTMTLGRSGGRLPYGVRMTAMGSSPNIASSGVAS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 DTIAFGEHHLPPVSMASTVPHSLRQARDNTIMDLQTQLKEVLRENDLLRKDVEVKESKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTIAFGEHHLPPVSMASTVPHSLRQARDNTIMDLQTQLKEVLRENDLLRKDVEVKESKLS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 SSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQDELRIQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQDELRIQR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 DLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 TLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSML
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 REEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEERE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEERE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 EEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 SLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 KERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERT
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 IERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 GLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 DESSKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTSRQVKDQNKKVANLKHKEQVEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DESSKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTSRQVKDQNKKVANLKHKEQVEK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA1 KKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEE
790 800 810 820 830 840
850 860 870 880
pF1KA1 SARTNAEKQ------------------VEELLMAMEKVKQELESMKAKLSSTQQSLAEKE
::::::::: :::::::::::::::::::::::::::::::::
XP_016 SARTNAEKQLLREILHETSYLNFKWFKVEELLMAMEKVKQELESMKAKLSSTQQSLAEKE
850 860 870 880 890 900
890 900 910 920 930 940
pF1KA1 THLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQEEVAALKREKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 THLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQEEVAALKREKD
910 920 930 940 950 960
950 960 970 980 990
pF1KA1 RLVQQLKQQTQNRMKLMADNYEDDHFKSSHSNQTNHKPSPDQDEEEGIWA
::::::::::::::::::::::::::::::::::::::::::
XP_016 RLVQQLKQQTQNRMKLMADNYEDDHFKSSHSNQTNHKPSPDQIIQPLLELDQNRSKLKLY
970 980 990 1000 1010 1020
XP_016 IGHLTTLCHDRDPLILRGLTPPASYNLDDDQAAWENELQKMTRGQLQDELEKGERDNAEL
1030 1040 1050 1060 1070 1080
>>XP_016874560 (OMIM: 607127) PREDICTED: ELKS/Rab6-inter (1048 aa)
initn: 5024 init1: 5024 opt: 5108 Z-score: 1893.3 bits: 361.9 E(85289): 1e-98
Smith-Waterman score: 5755; 95.5% identity (95.5% similar) in 984 aa overlap (1-984:1-940)
10 20 30 40 50 60
pF1KA1 MYGSARSVGKVEPSSQSPGRSPRLPRSPRLGHRRTNSTGGSSGSSVGGGSGKTLSMENIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MYGSARSVGKVEPSSQSPGRSPRLPRSPRLGHRRTNSTGGSSGSSVGGGSGKTLSMENIQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 SLNAAYATSGPMYLSDHENVGSETPKSTMTLGRSGGRLPYGVRMTAMGSSPNIASSGVAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLNAAYATSGPMYLSDHENVGSETPKSTMTLGRSGGRLPYGVRMTAMGSSPNIASSGVAS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 DTIAFGEHHLPPVSMASTVPHSLRQARDNTIMDLQTQLKEVLRENDLLRKDVEVKESKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTIAFGEHHLPPVSMASTVPHSLRQARDNTIMDLQTQLKEVLRENDLLRKDVEVKESKLS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 SSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQDELRIQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQDELRIQR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 DLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 TLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSML
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 REEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEERE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEERE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 EEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 SLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 KERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERT
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 IERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 GLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 DESSKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTSRQVKDQNKKVANLKHKEQVEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DESSKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTSRQVKDQNKKVANLKHKEQVEK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA1 KKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEE
:::::::::::::::::::::::::
XP_016 KKSAQMLEEARRREDNLNDSSQQLQ-----------------------------------
790 800
850 860 870 880 890 900
pF1KA1 SARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVL
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ---------VEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVL
810 820 830 840 850
910 920 930 940 950 960
pF1KA1 EMKQEALLAAISEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKLMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EMKQEALLAAISEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKLMA
860 870 880 890 900 910
970 980 990
pF1KA1 DNYEDDHFKSSHSNQTNHKPSPDQDEEEGIWA
::::::::::::::::::::::::
XP_016 DNYEDDHFKSSHSNQTNHKPSPDQIIQPLLELDQNRSKLKLYIGHLTTLCHDRDPLILRG
920 930 940 950 960 970
>>XP_016874551 (OMIM: 607127) PREDICTED: ELKS/Rab6-inter (1120 aa)
initn: 3331 init1: 3331 opt: 3396 Z-score: 1268.0 bits: 246.3 E(85289): 6.9e-64
Smith-Waterman score: 6049; 97.2% identity (97.2% similar) in 1012 aa overlap (1-984:1-1012)
10 20 30 40 50 60
pF1KA1 MYGSARSVGKVEPSSQSPGRSPRLPRSPRLGHRRTNSTGGSSGSSVGGGSGKTLSMENIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MYGSARSVGKVEPSSQSPGRSPRLPRSPRLGHRRTNSTGGSSGSSVGGGSGKTLSMENIQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 SLNAAYATSGPMYLSDHENVGSETPKSTMTLGRSGGRLPYGVRMTAMGSSPNIASSGVAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLNAAYATSGPMYLSDHENVGSETPKSTMTLGRSGGRLPYGVRMTAMGSSPNIASSGVAS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 DTIAFGEHHLPPVSMASTVPHSLRQARDNTIMDLQTQLKEVLRENDLLRKDVEVKESKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTIAFGEHHLPPVSMASTVPHSLRQARDNTIMDLQTQLKEVLRENDLLRKDVEVKESKLS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 SSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQDELRIQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQDELRIQR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 DLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 TLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSML
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 REEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEERE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEERE
370 380 390 400 410 420
430 440 450
pF1KA1 EEMKQMEVYRSHSKFMKNK----------------------------IGQVKQELSRKDT
::::::::::::::::::: :::::::::::::
XP_016 EEMKQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDT
430 440 450 460 470 480
460 470 480 490 500 510
pF1KA1 ELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNK
490 500 510 520 530 540
520 530 540 550 560 570
pF1KA1 KTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKER
550 560 570 580 590 600
580 590 600 610 620 630
pF1KA1 VKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEK
610 620 630 640 650 660
640 650 660 670 680 690
pF1KA1 VSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKA
670 680 690 700 710 720
700 710 720 730 740 750
pF1KA1 HEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIA
730 740 750 760 770 780
760 770 780 790 800 810
pF1KA1 ELESLTSRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELESLTSRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKD
790 800 810 820 830 840
820 830 840 850 860 870
pF1KA1 DRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLS
850 860 870 880 890 900
880 890 900 910 920 930
pF1KA1 STQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQE
910 920 930 940 950 960
940 950 960 970 980 990
pF1KA1 EVAALKREKDRLVQQLKQQTQNRMKLMADNYEDDHFKSSHSNQTNHKPSPDQDEEEGIWA
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVAALKREKDRLVQQLKQQTQNRMKLMADNYEDDHFKSSHSNQTNHKPSPDQIIQPLLEL
970 980 990 1000 1010 1020
XP_016 DQNRSKLKLYIGHLTTLCHDRDPLILRGLTPPASYNLDDDQAAWENELQKMTRGQLQDEL
1030 1040 1050 1060 1070 1080
>>XP_016874550 (OMIM: 607127) PREDICTED: ELKS/Rab6-inter (1123 aa)
initn: 3314 init1: 3314 opt: 3376 Z-score: 1260.7 bits: 244.9 E(85289): 1.8e-63
Smith-Waterman score: 6043; 96.9% identity (96.9% similar) in 1015 aa overlap (1-984:1-1015)
10 20 30 40 50 60
pF1KA1 MYGSARSVGKVEPSSQSPGRSPRLPRSPRLGHRRTNSTGGSSGSSVGGGSGKTLSMENIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MYGSARSVGKVEPSSQSPGRSPRLPRSPRLGHRRTNSTGGSSGSSVGGGSGKTLSMENIQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 SLNAAYATSGPMYLSDHENVGSETPKSTMTLGRSGGRLPYGVRMTAMGSSPNIASSGVAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLNAAYATSGPMYLSDHENVGSETPKSTMTLGRSGGRLPYGVRMTAMGSSPNIASSGVAS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 DTIAFGEHHLPPVSMASTVPHSLRQARDNTIMDLQTQLKEVLRENDLLRKDVEVKESKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTIAFGEHHLPPVSMASTVPHSLRQARDNTIMDLQTQLKEVLRENDLLRKDVEVKESKLS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 SSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQDELRIQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQDELRIQR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 DLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 TLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSML
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 REEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEERE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEERE
370 380 390 400 410 420
430 440
pF1KA1 EEMKQMEVYRSHSKFMKNK-------------------------------IGQVKQELSR
::::::::::::::::::: ::::::::::
XP_016 EEMKQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKKAAGLQAEVFAIGQVKQELSR
430 440 450 460 470 480
450 460 470 480 490 500
pF1KA1 KDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETM
490 500 510 520 530 540
510 520 530 540 550 560
pF1KA1 LNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSL
550 560 570 580 590 600
570 580 590 600 610 620
pF1KA1 KERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDL
610 620 630 640 650 660
630 640 650 660 670 680
pF1KA1 KEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQL
670 680 690 700 710 720
690 700 710 720 730 740
pF1KA1 KKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDK
730 740 750 760 770 780
750 760 770 780 790 800
pF1KA1 KIAELESLTSRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KIAELESLTSRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLR
790 800 810 820 830 840
810 820 830 840 850 860
pF1KA1 KKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKA
850 860 870 880 890 900
870 880 890 900 910 920
pF1KA1 KLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKK
910 920 930 940 950 960
930 940 950 960 970 980
pF1KA1 TQEEVAALKREKDRLVQQLKQQTQNRMKLMADNYEDDHFKSSHSNQTNHKPSPDQDEEEG
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TQEEVAALKREKDRLVQQLKQQTQNRMKLMADNYEDDHFKSSHSNQTNHKPSPDQIIQPL
970 980 990 1000 1010 1020
990
pF1KA1 IWA
XP_016 LELDQNRSKLKLYIGHLTTLCHDRDPLILRGLTPPASYNLDDDQAAWENELQKMTRGQLQ
1030 1040 1050 1060 1070 1080
>>XP_016874549 (OMIM: 607127) PREDICTED: ELKS/Rab6-inter (1134 aa)
initn: 3861 init1: 2917 opt: 3142 Z-score: 1175.2 bits: 229.1 E(85289): 1e-58
Smith-Waterman score: 5950; 95.1% identity (95.1% similar) in 1028 aa overlap (1-982:1-1024)
10 20 30 40 50 60
pF1KA1 MYGSARSVGKVEPSSQSPGRSPRLPRSPRLGHRRTNSTGGSSGSSVGGGSGKTLSMENIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MYGSARSVGKVEPSSQSPGRSPRLPRSPRLGHRRTNSTGGSSGSSVGGGSGKTLSMENIQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 SLNAAYATSGPMYLSDHENVGSETPKSTMTLGRSGGRLPYGVRMTAMGSSPNIASSGVAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLNAAYATSGPMYLSDHENVGSETPKSTMTLGRSGGRLPYGVRMTAMGSSPNIASSGVAS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 DTIAFGEHHLPPVSMASTVPHSLRQARDNTIMDLQTQLKEVLRENDLLRKDVEVKESKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTIAFGEHHLPPVSMASTVPHSLRQARDNTIMDLQTQLKEVLRENDLLRKDVEVKESKLS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 SSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQDELRIQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQDELRIQR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 DLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 TLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSML
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 REEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEERE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEERE
370 380 390 400 410 420
430 440 450
pF1KA1 EEMKQMEVYRSHSKFMKNK----------------------------IGQVKQELSRKDT
::::::::::::::::::: :::::::::::::
XP_016 EEMKQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDT
430 440 450 460 470 480
460 470 480 490 500 510
pF1KA1 ELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNK
490 500 510 520 530 540
520 530 540 550 560 570
pF1KA1 KTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKER
550 560 570 580 590 600
580 590 600 610 620 630
pF1KA1 VKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEK
610 620 630 640 650 660
640 650 660 670 680 690
pF1KA1 VSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKA
670 680 690 700 710 720
700 710 720 730 740 750
pF1KA1 HEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIA
730 740 750 760 770 780
760 770 780 790 800 810
pF1KA1 ELESLTSRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKD
::: :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELE----RQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKD
790 800 810 820 830
820 830 840 850
pF1KA1 DRIEELEEALRESVQITAEREMVLAQEESARTNAEKQ------------------VEELL
::::::::::::::::::::::::::::::::::::: :::::
XP_016 DRIEELEEALRESVQITAEREMVLAQEESARTNAEKQLLREILHETSYLNFKWFKVEELL
840 850 860 870 880 890
860 870 880 890 900 910
pF1KA1 MAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEK
900 910 920 930 940 950
920 930 940 950 960 970
pF1KA1 DANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKLMADNYEDDHFKSSHSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKLMADNYEDDHFKSSHSN
960 970 980 990 1000 1010
980 990
pF1KA1 QTNHKPSPDQDEEEGIWA
::::::::
XP_016 QTNHKPSPDQIIQPLLELDQNRSKLKLYIGHLTTLCHDRDPLILRGLTPPASYNLDDDQA
1020 1030 1040 1050 1060 1070
>>NP_001288177 (OMIM: 607127) ELKS/Rab6-interacting/CAST (1086 aa)
initn: 4360 init1: 2917 opt: 3122 Z-score: 1168.1 bits: 227.8 E(85289): 2.5e-58
Smith-Waterman score: 6011; 96.8% identity (96.8% similar) in 1012 aa overlap (1-984:1-1008)
10 20 30 40 50 60
pF1KA1 MYGSARSVGKVEPSSQSPGRSPRLPRSPRLGHRRTNSTGGSSGSSVGGGSGKTLSMENIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MYGSARSVGKVEPSSQSPGRSPRLPRSPRLGHRRTNSTGGSSGSSVGGGSGKTLSMENIQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 SLNAAYATSGPMYLSDHENVGSETPKSTMTLGRSGGRLPYGVRMTAMGSSPNIASSGVAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLNAAYATSGPMYLSDHENVGSETPKSTMTLGRSGGRLPYGVRMTAMGSSPNIASSGVAS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 DTIAFGEHHLPPVSMASTVPHSLRQARDNTIMDLQTQLKEVLRENDLLRKDVEVKESKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DTIAFGEHHLPPVSMASTVPHSLRQARDNTIMDLQTQLKEVLRENDLLRKDVEVKESKLS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 SSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQDELRIQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQDELRIQR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 DLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 TLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSML
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 REEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEERE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEERE
370 380 390 400 410 420
430 440 450
pF1KA1 EEMKQMEVYRSHSKFMKNK----------------------------IGQVKQELSRKDT
::::::::::::::::::: :::::::::::::
NP_001 EEMKQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDT
430 440 450 460 470 480
460 470 480 490 500 510
pF1KA1 ELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNK
490 500 510 520 530 540
520 530 540 550 560 570
pF1KA1 KTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKER
550 560 570 580 590 600
580 590 600 610 620 630
pF1KA1 VKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEK
610 620 630 640 650 660
640 650 660 670 680 690
pF1KA1 VSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKA
670 680 690 700 710 720
700 710 720 730 740 750
pF1KA1 HEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIA
730 740 750 760 770 780
760 770 780 790 800 810
pF1KA1 ELESLTSRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKD
::: :::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELE----RQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKD
790 800 810 820 830
820 830 840 850 860 870
pF1KA1 DRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLS
840 850 860 870 880 890
880 890 900 910 920 930
pF1KA1 STQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQE
900 910 920 930 940 950
940 950 960 970 980 990
pF1KA1 EVAALKREKDRLVQQLKQQTQNRMKLMADNYEDDHFKSSHSNQTNHKPSPDQDEEEGIWA
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVAALKREKDRLVQQLKQQTQNRMKLMADNYEDDHFKSSHSNQTNHKPSPDQIIQPLLEL
960 970 980 990 1000 1010
NP_001 DQNRSKLKLYIGHLTTLCHDRDPLILRGLTPPASYNLDDDQAAWENELQKMTRGQNPLHP
1020 1030 1040 1050 1060 1070
>>XP_016874557 (OMIM: 607127) PREDICTED: ELKS/Rab6-inter (1086 aa)
initn: 4360 init1: 2917 opt: 3122 Z-score: 1168.1 bits: 227.8 E(85289): 2.5e-58
Smith-Waterman score: 6011; 96.8% identity (96.8% similar) in 1012 aa overlap (1-984:1-1008)
10 20 30 40 50 60
pF1KA1 MYGSARSVGKVEPSSQSPGRSPRLPRSPRLGHRRTNSTGGSSGSSVGGGSGKTLSMENIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MYGSARSVGKVEPSSQSPGRSPRLPRSPRLGHRRTNSTGGSSGSSVGGGSGKTLSMENIQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 SLNAAYATSGPMYLSDHENVGSETPKSTMTLGRSGGRLPYGVRMTAMGSSPNIASSGVAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLNAAYATSGPMYLSDHENVGSETPKSTMTLGRSGGRLPYGVRMTAMGSSPNIASSGVAS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 DTIAFGEHHLPPVSMASTVPHSLRQARDNTIMDLQTQLKEVLRENDLLRKDVEVKESKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTIAFGEHHLPPVSMASTVPHSLRQARDNTIMDLQTQLKEVLRENDLLRKDVEVKESKLS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 SSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQDELRIQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQDELRIQR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 DLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 TLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSML
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 REEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEERE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEERE
370 380 390 400 410 420
430 440 450
pF1KA1 EEMKQMEVYRSHSKFMKNK----------------------------IGQVKQELSRKDT
::::::::::::::::::: :::::::::::::
XP_016 EEMKQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDT
430 440 450 460 470 480
460 470 480 490 500 510
pF1KA1 ELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNK
490 500 510 520 530 540
520 530 540 550 560 570
pF1KA1 KTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKER
550 560 570 580 590 600
580 590 600 610 620 630
pF1KA1 VKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEK
610 620 630 640 650 660
640 650 660 670 680 690
pF1KA1 VSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKA
670 680 690 700 710 720
700 710 720 730 740 750
pF1KA1 HEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIA
730 740 750 760 770 780
760 770 780 790 800 810
pF1KA1 ELESLTSRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKD
::: :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELE----RQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKD
790 800 810 820 830
820 830 840 850 860 870
pF1KA1 DRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLS
840 850 860 870 880 890
880 890 900 910 920 930
pF1KA1 STQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQE
900 910 920 930 940 950
940 950 960 970 980 990
pF1KA1 EVAALKREKDRLVQQLKQQTQNRMKLMADNYEDDHFKSSHSNQTNHKPSPDQDEEEGIWA
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVAALKREKDRLVQQLKQQTQNRMKLMADNYEDDHFKSSHSNQTNHKPSPDQIIQPLLEL
960 970 980 990 1000 1010
XP_016 DQNRSKLKLYIGHLTTLCHDRDPLILRGLTPPASYNLDDDQAAWENELQKMTRGQNPLHP
1020 1030 1040 1050 1060 1070
992 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 20:26:18 2016 done: Wed Nov 2 20:26:20 2016
Total Scan time: 15.360 Total Display time: 0.450
Function used was FASTA [36.3.4 Apr, 2011]