FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1090, 1365 aa 1>>>pF1KA1090 1365 - 1365 aa - 1365 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.6962+/-0.000428; mu= 13.4530+/- 0.027 mean_var=228.7368+/-48.025, 0's: 0 Z-trim(118.2): 295 B-trim: 124 in 1/53 Lambda= 0.084802 statistics sampled from 30627 (31013) to 30627 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.701), E-opt: 0.2 (0.364), width: 16 Scan time: 12.760 The best scores are: opt bits E(85289) NP_579890 (OMIM: 194190,602952) histone-lysine N-m (1365) 9510 1178.2 0 NP_579878 (OMIM: 194190,602952) histone-lysine N-m (1365) 9510 1178.2 0 XP_005248058 (OMIM: 194190,602952) PREDICTED: hist (1365) 9510 1178.2 0 NP_579877 (OMIM: 194190,602952) histone-lysine N-m (1365) 9510 1178.2 0 XP_011511859 (OMIM: 194190,602952) PREDICTED: hist (1365) 9510 1178.2 0 NP_001035889 (OMIM: 194190,602952) histone-lysine (1365) 9510 1178.2 0 XP_005248059 (OMIM: 194190,602952) PREDICTED: hist (1296) 5419 677.6 1.6e-193 XP_016864077 (OMIM: 194190,602952) PREDICTED: hist ( 584) 4302 540.6 1.3e-152 XP_011511862 (OMIM: 194190,602952) PREDICTED: hist ( 584) 4302 540.6 1.3e-152 XP_016864076 (OMIM: 194190,602952) PREDICTED: hist ( 584) 4302 540.6 1.3e-152 NP_015627 (OMIM: 194190,602952) histone-lysine N-m ( 629) 4107 516.8 2e-145 XP_006713977 (OMIM: 194190,602952) PREDICTED: hist ( 647) 4104 516.4 2.7e-145 XP_005248062 (OMIM: 194190,602952) PREDICTED: hist ( 647) 4104 516.4 2.7e-145 NP_579889 (OMIM: 194190,602952) histone-lysine N-m ( 647) 4104 516.4 2.7e-145 NP_758859 (OMIM: 117550,130650,606681) histone-lys (2427) 3606 456.1 1.4e-126 NP_071900 (OMIM: 117550,130650,606681) histone-lys (2696) 3606 456.2 1.5e-126 NP_075447 (OMIM: 607083) histone-lysine N-methyltr (1437) 2691 343.9 4.9e-93 XP_011531936 (OMIM: 612778,616831) PREDICTED: hist (2520) 706 101.4 9e-20 NP_054878 (OMIM: 612778,616831) histone-lysine N-m (2564) 706 101.4 9.1e-20 XP_011531934 (OMIM: 612778,616831) PREDICTED: hist (2572) 706 101.4 9.1e-20 XP_011531933 (OMIM: 612778,616831) PREDICTED: hist (2590) 706 101.4 9.2e-20 XP_011531935 (OMIM: 612778,616831) PREDICTED: hist (2545) 697 100.3 1.9e-19 XP_016857277 (OMIM: 607999) PREDICTED: histone-lys (1244) 648 93.9 7.8e-18 XP_011508072 (OMIM: 607999) PREDICTED: histone-lys (1244) 648 93.9 7.8e-18 XP_016857275 (OMIM: 607999) PREDICTED: histone-lys (2663) 648 94.3 1.3e-17 XP_006711515 (OMIM: 607999) PREDICTED: histone-lys (2904) 648 94.3 1.4e-17 XP_006711514 (OMIM: 607999) PREDICTED: histone-lys (2964) 648 94.3 1.4e-17 XP_016857274 (OMIM: 607999) PREDICTED: histone-lys (2964) 648 94.3 1.4e-17 XP_016857273 (OMIM: 607999) PREDICTED: histone-lys (2964) 648 94.3 1.4e-17 XP_006711513 (OMIM: 607999) PREDICTED: histone-lys (2964) 648 94.3 1.4e-17 NP_060959 (OMIM: 607999) histone-lysine N-methyltr (2964) 648 94.3 1.4e-17 NP_060248 (OMIM: 607083) histone-lysine N-methyltr ( 645) 545 81.0 3.1e-14 XP_011514198 (OMIM: 277590,601573) PREDICTED: hist ( 673) 351 57.3 4.5e-07 XP_016879841 (OMIM: 601674) PREDICTED: histone-lys ( 410) 347 56.5 4.6e-07 NP_001190178 (OMIM: 277590,601573) histone-lysine ( 695) 351 57.3 4.6e-07 XP_005250021 (OMIM: 277590,601573) PREDICTED: hist ( 703) 351 57.3 4.6e-07 XP_016867308 (OMIM: 277590,601573) PREDICTED: hist ( 712) 351 57.3 4.7e-07 XP_011514194 (OMIM: 277590,601573) PREDICTED: hist ( 717) 351 57.3 4.7e-07 XP_016879840 (OMIM: 601674) PREDICTED: histone-lys ( 637) 347 56.7 6.1e-07 XP_016879839 (OMIM: 601674) PREDICTED: histone-lys ( 668) 347 56.8 6.3e-07 NP_001308011 (OMIM: 601674) histone-lysine N-methy ( 707) 347 56.8 6.6e-07 XP_005257202 (OMIM: 601674) PREDICTED: histone-lys ( 713) 347 56.8 6.6e-07 NP_001308010 (OMIM: 601674) histone-lysine N-methy ( 738) 347 56.8 6.7e-07 XP_011522819 (OMIM: 601674) PREDICTED: histone-lys ( 744) 347 56.8 6.8e-07 NP_001982 (OMIM: 601674) histone-lysine N-methyltr ( 747) 347 56.8 6.8e-07 NP_001308008 (OMIM: 601674) histone-lysine N-methy ( 753) 347 56.8 6.8e-07 XP_016867310 (OMIM: 277590,601573) PREDICTED: hist ( 637) 332 54.9 2.2e-06 XP_011514199 (OMIM: 277590,601573) PREDICTED: hist ( 642) 332 54.9 2.2e-06 XP_011514200 (OMIM: 277590,601573) PREDICTED: hist ( 642) 332 54.9 2.2e-06 XP_016867309 (OMIM: 277590,601573) PREDICTED: hist ( 703) 332 55.0 2.3e-06 >>NP_579890 (OMIM: 194190,602952) histone-lysine N-methy (1365 aa) initn: 9510 init1: 9510 opt: 9510 Z-score: 6300.3 bits: 1178.2 E(85289): 0 Smith-Waterman score: 9510; 100.0% identity (100.0% similar) in 1365 aa overlap (1-1365:1-1365) 10 20 30 40 50 60 pF1KA1 MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 NRASTAASSALGFSKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSKKSER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 NRASTAASSALGFSKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSKKSER 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 GVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 GVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVC 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 KESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 KESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKG 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 KMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNVSWCFVCSKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 KMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNVSWCFVCSKG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 GSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 GSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCH 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 PKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 PKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKN 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 ALQEAEARFREIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 ALQEAEARFREIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKP 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA1 TDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 TDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAK 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA1 RDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 RDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFM 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA1 NHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 NHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSG 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA1 FLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 FLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCT 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA1 KAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 KAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGR 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 pF1KA1 SYCCEHDLGAASVRSTKTEKPPPEPGKPKGKRRRRRGWRRVTEGK ::::::::::::::::::::::::::::::::::::::::::::: NP_579 SYCCEHDLGAASVRSTKTEKPPPEPGKPKGKRRRRRGWRRVTEGK 1330 1340 1350 1360 >>NP_579878 (OMIM: 194190,602952) histone-lysine N-methy (1365 aa) initn: 9510 init1: 9510 opt: 9510 Z-score: 6300.3 bits: 1178.2 E(85289): 0 Smith-Waterman score: 9510; 100.0% identity (100.0% similar) in 1365 aa overlap (1-1365:1-1365) 10 20 30 40 50 60 pF1KA1 MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 NRASTAASSALGFSKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSKKSER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 NRASTAASSALGFSKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSKKSER 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 GVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 GVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVC 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 KESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 KESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKG 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 KMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNVSWCFVCSKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 KMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNVSWCFVCSKG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 GSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 GSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCH 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 PKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 PKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKN 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 ALQEAEARFREIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 ALQEAEARFREIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKP 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA1 TDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 TDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAK 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA1 RDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 RDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFM 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA1 NHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 NHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSG 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA1 FLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 FLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCT 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA1 KAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 KAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGR 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 pF1KA1 SYCCEHDLGAASVRSTKTEKPPPEPGKPKGKRRRRRGWRRVTEGK ::::::::::::::::::::::::::::::::::::::::::::: NP_579 SYCCEHDLGAASVRSTKTEKPPPEPGKPKGKRRRRRGWRRVTEGK 1330 1340 1350 1360 >>XP_005248058 (OMIM: 194190,602952) PREDICTED: histone- (1365 aa) initn: 9510 init1: 9510 opt: 9510 Z-score: 6300.3 bits: 1178.2 E(85289): 0 Smith-Waterman score: 9510; 100.0% identity (100.0% similar) in 1365 aa overlap (1-1365:1-1365) 10 20 30 40 50 60 pF1KA1 MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 NRASTAASSALGFSKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSKKSER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NRASTAASSALGFSKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSKKSER 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 GVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVC 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 KESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKG 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 KMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNVSWCFVCSKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNVSWCFVCSKG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 GSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCH 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 PKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKN 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 ALQEAEARFREIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ALQEAEARFREIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKP 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA1 TDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAK 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA1 RDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFM 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA1 NHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSG 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA1 FLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCT 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA1 KAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGR 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 pF1KA1 SYCCEHDLGAASVRSTKTEKPPPEPGKPKGKRRRRRGWRRVTEGK ::::::::::::::::::::::::::::::::::::::::::::: XP_005 SYCCEHDLGAASVRSTKTEKPPPEPGKPKGKRRRRRGWRRVTEGK 1330 1340 1350 1360 >>NP_579877 (OMIM: 194190,602952) histone-lysine N-methy (1365 aa) initn: 9510 init1: 9510 opt: 9510 Z-score: 6300.3 bits: 1178.2 E(85289): 0 Smith-Waterman score: 9510; 100.0% identity (100.0% similar) in 1365 aa overlap (1-1365:1-1365) 10 20 30 40 50 60 pF1KA1 MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 NRASTAASSALGFSKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSKKSER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 NRASTAASSALGFSKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSKKSER 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 GVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 GVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVC 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 KESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 KESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKG 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 KMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNVSWCFVCSKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 KMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNVSWCFVCSKG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 GSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 GSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCH 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 PKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 PKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKN 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 ALQEAEARFREIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 ALQEAEARFREIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKP 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA1 TDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 TDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAK 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA1 RDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 RDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFM 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA1 NHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 NHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSG 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA1 FLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 FLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCT 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA1 KAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_579 KAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGR 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 pF1KA1 SYCCEHDLGAASVRSTKTEKPPPEPGKPKGKRRRRRGWRRVTEGK ::::::::::::::::::::::::::::::::::::::::::::: NP_579 SYCCEHDLGAASVRSTKTEKPPPEPGKPKGKRRRRRGWRRVTEGK 1330 1340 1350 1360 >>XP_011511859 (OMIM: 194190,602952) PREDICTED: histone- (1365 aa) initn: 9510 init1: 9510 opt: 9510 Z-score: 6300.3 bits: 1178.2 E(85289): 0 Smith-Waterman score: 9510; 100.0% identity (100.0% similar) in 1365 aa overlap (1-1365:1-1365) 10 20 30 40 50 60 pF1KA1 MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 NRASTAASSALGFSKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSKKSER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NRASTAASSALGFSKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSKKSER 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 GVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVC 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 KESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKG 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 KMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNVSWCFVCSKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNVSWCFVCSKG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 GSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCH 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 PKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKN 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 ALQEAEARFREIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALQEAEARFREIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKP 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA1 TDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAK 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA1 RDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFM 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA1 NHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSG 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA1 FLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCT 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA1 KAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGR 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 pF1KA1 SYCCEHDLGAASVRSTKTEKPPPEPGKPKGKRRRRRGWRRVTEGK ::::::::::::::::::::::::::::::::::::::::::::: XP_011 SYCCEHDLGAASVRSTKTEKPPPEPGKPKGKRRRRRGWRRVTEGK 1330 1340 1350 1360 >>NP_001035889 (OMIM: 194190,602952) histone-lysine N-me (1365 aa) initn: 9510 init1: 9510 opt: 9510 Z-score: 6300.3 bits: 1178.2 E(85289): 0 Smith-Waterman score: 9510; 100.0% identity (100.0% similar) in 1365 aa overlap (1-1365:1-1365) 10 20 30 40 50 60 pF1KA1 MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 NRASTAASSALGFSKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSKKSER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NRASTAASSALGFSKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSKKSER 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 GVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVC 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 KESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKG 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 KMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNVSWCFVCSKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNVSWCFVCSKG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 GSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCH 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 PKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKN 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 ALQEAEARFREIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALQEAEARFREIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKP 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA1 TDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAK 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA1 RDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFM 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA1 NHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSG 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA1 FLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCT 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA1 KAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGR 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 pF1KA1 SYCCEHDLGAASVRSTKTEKPPPEPGKPKGKRRRRRGWRRVTEGK ::::::::::::::::::::::::::::::::::::::::::::: NP_001 SYCCEHDLGAASVRSTKTEKPPPEPGKPKGKRRRRRGWRRVTEGK 1330 1340 1350 1360 >>XP_005248059 (OMIM: 194190,602952) PREDICTED: histone- (1296 aa) initn: 5409 init1: 5409 opt: 5419 Z-score: 3595.6 bits: 677.6 E(85289): 1.6e-193 Smith-Waterman score: 8952; 94.9% identity (94.9% similar) in 1365 aa overlap (1-1365:1-1296) 10 20 30 40 50 60 pF1KA1 MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MEFSIKQSPLSVQSVVKCIKMKQAPEILGSANGKTPSCEVNRECSVFLSKAQLSSSLQEG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VMQKFNGHDALPFIPADKLKDLTSRVFNGEPGAHDAKLRFESQEMKGIGTPPNTTPIKNG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SPEIKLKITKTYMNGKPLFESSICGDSAADVSQSEENGQKPENKARRNRKRSIKYDSLLE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QGLVEAALVSKISSPSDKKIPAKKESCPNTGRDKDHLLKYNVGDLVWSKVSGYPWWPCMV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFEKSLVAFEGEGQFEKLCQESAKQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 APTKAEKIKLLKPISGKLRAQWEMGIVQAEEAASMSVEERKAKFTFLYVGDQLHLNPQVA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KEAGIAAESLGEMAESSGVSEEAAENPKSVREECIPMKRRRRAKLCSSAETLESHPDIGK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 STPQKTAEADPRRGVGSPPGRKKTTVSMPRSRKGDAASQFLVFCQKHRDEVVAEHPDASG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EEIEELLRSQWSLLSEKQRARYNTKFALVAPVQAEEDSGNVNGKKRNHTKRIQDPTEDAE 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 AEDTPRKRLRTDKHSLRKRDTITDKTARTSSYKAMEAASSLKSQAATKNLSDACKPLKKR :::::::::::::::::: XP_005 AEDTPRKRLRTDKHSLRK------------------------------------------ 550 610 620 630 640 650 660 pF1KA1 NRASTAASSALGFSKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSKKSER ::::::::::::::::::::::::::::::::: XP_005 ---------------------------VSDSPGDEPSESPYESADETQTEVSVSSKKSER 560 570 580 590 670 680 690 700 710 720 pF1KA1 GVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GVTAKKEYVCQLCEKPGSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIHSCFVC 600 610 620 630 640 650 730 740 750 760 770 780 pF1KA1 KESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KESKTDVKRCVVTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHASNPSNPRPSKG 660 670 680 690 700 710 790 800 810 820 830 840 pF1KA1 KMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNVSWCFVCSKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAHFTARKGKRHHAHVNVSWCFVCSKG 720 730 740 750 760 770 850 860 870 880 890 900 pF1KA1 GSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCH 780 790 800 810 820 830 910 920 930 940 950 960 pF1KA1 PKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKN 840 850 860 870 880 890 970 980 990 1000 1010 1020 pF1KA1 ALQEAEARFREIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ALQEAEARFREIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKP 900 910 920 930 940 950 1030 1040 1050 1060 1070 1080 pF1KA1 TDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TDENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAK 960 970 980 990 1000 1010 1090 1100 1110 1120 1130 1140 pF1KA1 RDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFM 1020 1030 1040 1050 1060 1070 1150 1160 1170 1180 1190 1200 pF1KA1 NHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSG 1080 1090 1100 1110 1120 1130 1210 1220 1230 1240 1250 1260 pF1KA1 FLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDRKFCT 1140 1150 1160 1170 1180 1190 1270 1280 1290 1300 1310 1320 pF1KA1 KAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGR 1200 1210 1220 1230 1240 1250 1330 1340 1350 1360 pF1KA1 SYCCEHDLGAASVRSTKTEKPPPEPGKPKGKRRRRRGWRRVTEGK ::::::::::::::::::::::::::::::::::::::::::::: XP_005 SYCCEHDLGAASVRSTKTEKPPPEPGKPKGKRRRRRGWRRVTEGK 1260 1270 1280 1290 >>XP_016864077 (OMIM: 194190,602952) PREDICTED: histone- (584 aa) initn: 4302 init1: 4302 opt: 4302 Z-score: 2861.1 bits: 540.6 E(85289): 1.3e-152 Smith-Waterman score: 4302; 100.0% identity (100.0% similar) in 584 aa overlap (782-1365:1-584) 760 770 780 790 800 810 pF1KA1 FESRGFRCPLHSCVSCHASNPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIASNSI :::::::::::::::::::::::::::::: XP_016 MMRCVRCPVAYHSGDACLAAGCSVIASNSI 10 20 30 820 830 840 850 860 870 pF1KA1 ICTAHFTARKGKRHHAHVNVSWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPDGSWFCND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ICTAHFTARKGKRHHAHVNVSWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPDGSWFCND 40 50 60 70 80 90 880 890 900 910 920 930 pF1KA1 CRAGKKLHFQDIIWVKLGNYRWWPAEVCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CRAGKKLHFQDIIWVKLGNYRWWPAEVCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWT 100 110 120 130 140 150 940 950 960 970 980 990 pF1KA1 HQARVFPYMEGDRGSRYQGVRGIGRVFKNALQEAEARFREIKLQREARETQESERKPPPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HQARVFPYMEGDRGSRYQGVRGIGRVFKNALQEAEARFREIKLQREARETQESERKPPPY 160 170 180 190 200 210 1000 1010 1020 1030 1040 1050 pF1KA1 KHIKVNKPYGKVQIYTADISEIPKCNCKPTDENPCGFDSECLNRMLMFECHPQVCPAGEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KHIKVNKPYGKVQIYTADISEIPKCNCKPTDENPCGFDSECLNRMLMFECHPQVCPAGEF 220 230 240 250 260 270 1060 1070 1080 1090 1100 1110 pF1KA1 CQNQCFTKRQYPETKIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CQNQCFTKRQYPETKIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHE 280 290 300 310 320 330 1120 1130 1140 1150 1160 1170 pF1KA1 NDITHFYMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NDITHFYMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPA 340 350 360 370 380 390 1180 1190 1200 1210 1220 1230 pF1KA1 GTELTFNYNLDCLGNEKTVCRCGASNCSGFLGDRPKTSTTLSSEEKGKKTKKKTRRRRAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GTELTFNYNLDCLGNEKTVCRCGASNCSGFLGDRPKTSTTLSSEEKGKKTKKKTRRRRAK 400 410 420 430 440 450 1240 1250 1260 1270 1280 1290 pF1KA1 GEGKRQSEDECFRCGDGGQLVLCDRKFCTKAYHLSCLGLGKRPFGKWECPWHHCDVCGKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GEGKRQSEDECFRCGDGGQLVLCDRKFCTKAYHLSCLGLGKRPFGKWECPWHHCDVCGKP 460 470 480 490 500 510 1300 1310 1320 1330 1340 1350 pF1KA1 STSFCHLCPNSFCKEHQDGTAFSCTPDGRSYCCEHDLGAASVRSTKTEKPPPEPGKPKGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 STSFCHLCPNSFCKEHQDGTAFSCTPDGRSYCCEHDLGAASVRSTKTEKPPPEPGKPKGK 520 530 540 550 560 570 1360 pF1KA1 RRRRRGWRRVTEGK :::::::::::::: XP_016 RRRRRGWRRVTEGK 580 >>XP_011511862 (OMIM: 194190,602952) PREDICTED: histone- (584 aa) initn: 4302 init1: 4302 opt: 4302 Z-score: 2861.1 bits: 540.6 E(85289): 1.3e-152 Smith-Waterman score: 4302; 100.0% identity (100.0% similar) in 584 aa overlap (782-1365:1-584) 760 770 780 790 800 810 pF1KA1 FESRGFRCPLHSCVSCHASNPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIASNSI :::::::::::::::::::::::::::::: XP_011 MMRCVRCPVAYHSGDACLAAGCSVIASNSI 10 20 30 820 830 840 850 860 870 pF1KA1 ICTAHFTARKGKRHHAHVNVSWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPDGSWFCND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ICTAHFTARKGKRHHAHVNVSWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPDGSWFCND 40 50 60 70 80 90 880 890 900 910 920 930 pF1KA1 CRAGKKLHFQDIIWVKLGNYRWWPAEVCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CRAGKKLHFQDIIWVKLGNYRWWPAEVCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWT 100 110 120 130 140 150 940 950 960 970 980 990 pF1KA1 HQARVFPYMEGDRGSRYQGVRGIGRVFKNALQEAEARFREIKLQREARETQESERKPPPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HQARVFPYMEGDRGSRYQGVRGIGRVFKNALQEAEARFREIKLQREARETQESERKPPPY 160 170 180 190 200 210 1000 1010 1020 1030 1040 1050 pF1KA1 KHIKVNKPYGKVQIYTADISEIPKCNCKPTDENPCGFDSECLNRMLMFECHPQVCPAGEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KHIKVNKPYGKVQIYTADISEIPKCNCKPTDENPCGFDSECLNRMLMFECHPQVCPAGEF 220 230 240 250 260 270 1060 1070 1080 1090 1100 1110 pF1KA1 CQNQCFTKRQYPETKIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CQNQCFTKRQYPETKIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHE 280 290 300 310 320 330 1120 1130 1140 1150 1160 1170 pF1KA1 NDITHFYMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NDITHFYMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPA 340 350 360 370 380 390 1180 1190 1200 1210 1220 1230 pF1KA1 GTELTFNYNLDCLGNEKTVCRCGASNCSGFLGDRPKTSTTLSSEEKGKKTKKKTRRRRAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GTELTFNYNLDCLGNEKTVCRCGASNCSGFLGDRPKTSTTLSSEEKGKKTKKKTRRRRAK 400 410 420 430 440 450 1240 1250 1260 1270 1280 1290 pF1KA1 GEGKRQSEDECFRCGDGGQLVLCDRKFCTKAYHLSCLGLGKRPFGKWECPWHHCDVCGKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GEGKRQSEDECFRCGDGGQLVLCDRKFCTKAYHLSCLGLGKRPFGKWECPWHHCDVCGKP 460 470 480 490 500 510 1300 1310 1320 1330 1340 1350 pF1KA1 STSFCHLCPNSFCKEHQDGTAFSCTPDGRSYCCEHDLGAASVRSTKTEKPPPEPGKPKGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STSFCHLCPNSFCKEHQDGTAFSCTPDGRSYCCEHDLGAASVRSTKTEKPPPEPGKPKGK 520 530 540 550 560 570 1360 pF1KA1 RRRRRGWRRVTEGK :::::::::::::: XP_011 RRRRRGWRRVTEGK 580 >>XP_016864076 (OMIM: 194190,602952) PREDICTED: histone- (584 aa) initn: 4302 init1: 4302 opt: 4302 Z-score: 2861.1 bits: 540.6 E(85289): 1.3e-152 Smith-Waterman score: 4302; 100.0% identity (100.0% similar) in 584 aa overlap (782-1365:1-584) 760 770 780 790 800 810 pF1KA1 FESRGFRCPLHSCVSCHASNPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIASNSI :::::::::::::::::::::::::::::: XP_016 MMRCVRCPVAYHSGDACLAAGCSVIASNSI 10 20 30 820 830 840 850 860 870 pF1KA1 ICTAHFTARKGKRHHAHVNVSWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPDGSWFCND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ICTAHFTARKGKRHHAHVNVSWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPDGSWFCND 40 50 60 70 80 90 880 890 900 910 920 930 pF1KA1 CRAGKKLHFQDIIWVKLGNYRWWPAEVCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CRAGKKLHFQDIIWVKLGNYRWWPAEVCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWT 100 110 120 130 140 150 940 950 960 970 980 990 pF1KA1 HQARVFPYMEGDRGSRYQGVRGIGRVFKNALQEAEARFREIKLQREARETQESERKPPPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HQARVFPYMEGDRGSRYQGVRGIGRVFKNALQEAEARFREIKLQREARETQESERKPPPY 160 170 180 190 200 210 1000 1010 1020 1030 1040 1050 pF1KA1 KHIKVNKPYGKVQIYTADISEIPKCNCKPTDENPCGFDSECLNRMLMFECHPQVCPAGEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KHIKVNKPYGKVQIYTADISEIPKCNCKPTDENPCGFDSECLNRMLMFECHPQVCPAGEF 220 230 240 250 260 270 1060 1070 1080 1090 1100 1110 pF1KA1 CQNQCFTKRQYPETKIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CQNQCFTKRQYPETKIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHE 280 290 300 310 320 330 1120 1130 1140 1150 1160 1170 pF1KA1 NDITHFYMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NDITHFYMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPA 340 350 360 370 380 390 1180 1190 1200 1210 1220 1230 pF1KA1 GTELTFNYNLDCLGNEKTVCRCGASNCSGFLGDRPKTSTTLSSEEKGKKTKKKTRRRRAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GTELTFNYNLDCLGNEKTVCRCGASNCSGFLGDRPKTSTTLSSEEKGKKTKKKTRRRRAK 400 410 420 430 440 450 1240 1250 1260 1270 1280 1290 pF1KA1 GEGKRQSEDECFRCGDGGQLVLCDRKFCTKAYHLSCLGLGKRPFGKWECPWHHCDVCGKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GEGKRQSEDECFRCGDGGQLVLCDRKFCTKAYHLSCLGLGKRPFGKWECPWHHCDVCGKP 460 470 480 490 500 510 1300 1310 1320 1330 1340 1350 pF1KA1 STSFCHLCPNSFCKEHQDGTAFSCTPDGRSYCCEHDLGAASVRSTKTEKPPPEPGKPKGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 STSFCHLCPNSFCKEHQDGTAFSCTPDGRSYCCEHDLGAASVRSTKTEKPPPEPGKPKGK 520 530 540 550 560 570 1360 pF1KA1 RRRRRGWRRVTEGK :::::::::::::: XP_016 RRRRRGWRRVTEGK 580 1365 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 20:27:10 2016 done: Wed Nov 2 20:27:11 2016 Total Scan time: 12.760 Total Display time: 0.560 Function used was FASTA [36.3.4 Apr, 2011]