Result of FASTA (omim) for
pF1KA1101
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA1101, 527 aa
1>>>pF1KA1101 527 - 527 aa - 527 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.6810+/-0.0006; mu= -11.4825+/- 0.036
mean_var=687.8740+/-148.641, 0's: 0 Z-trim(117.3): 1502 B-trim: 0 in 0/60
Lambda= 0.048901
statistics sampled from 27041 (29220) to 27041 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.686), E-opt: 0.2 (0.343), width: 16
Scan time: 10.510
The best scores are: opt bits E(85289)
NP_005100 (OMIM: 604046) serine/threonine-protein ( 527) 3426 257.8 5.8e-68
XP_011532633 (OMIM: 604046) PREDICTED: serine/thre ( 580) 3273 247.1 1.1e-64
XP_005265695 (OMIM: 604046) PREDICTED: serine/thre ( 460) 2798 213.4 1.2e-54
XP_016863090 (OMIM: 604046) PREDICTED: serine/thre ( 568) 2224 173.1 2.1e-42
XP_016863091 (OMIM: 604046) PREDICTED: serine/thre ( 335) 2174 169.2 1.8e-41
XP_016859303 (OMIM: 607648) PREDICTED: STE20/SPS1- ( 461) 2081 162.8 2e-39
XP_016859302 (OMIM: 607648) PREDICTED: STE20/SPS1- ( 535) 2081 162.9 2.2e-39
NP_037365 (OMIM: 607648) STE20/SPS1-related prolin ( 545) 2081 162.9 2.2e-39
XP_005246522 (OMIM: 607648) PREDICTED: STE20/SPS1- ( 524) 2077 162.6 2.6e-39
XP_016859304 (OMIM: 607648) PREDICTED: STE20/SPS1- ( 443) 1819 144.3 7.1e-34
XP_016859305 (OMIM: 607648) PREDICTED: STE20/SPS1- ( 393) 1815 144.0 8.1e-34
XP_016859306 (OMIM: 607648) PREDICTED: STE20/SPS1- ( 381) 1416 115.8 2.4e-25
XP_011517813 (OMIM: 606808,607101) PREDICTED: myos (1009) 653 62.6 6.6e-09
XP_011517812 (OMIM: 606808,607101) PREDICTED: myos (1135) 653 62.7 7e-09
XP_011517810 (OMIM: 606808,607101) PREDICTED: myos (1435) 653 62.8 8.1e-09
XP_011517808 (OMIM: 606808,607101) PREDICTED: myos (1523) 653 62.8 8.3e-09
XP_011517807 (OMIM: 606808,607101) PREDICTED: myos (1532) 653 62.8 8.4e-09
XP_011517806 (OMIM: 606808,607101) PREDICTED: myos (1565) 653 62.8 8.5e-09
XP_011517805 (OMIM: 606808,607101) PREDICTED: myos (1568) 653 62.9 8.5e-09
XP_011517804 (OMIM: 606808,607101) PREDICTED: myos (1612) 653 62.9 8.6e-09
XP_011517800 (OMIM: 606808,607101) PREDICTED: myos (1616) 653 62.9 8.6e-09
XP_011517801 (OMIM: 606808,607101) PREDICTED: myos (1616) 653 62.9 8.6e-09
XP_011517802 (OMIM: 606808,607101) PREDICTED: myos (1616) 653 62.9 8.6e-09
NP_059129 (OMIM: 606808,607101) myosin-IIIa [Homo (1616) 653 62.9 8.6e-09
NP_001257354 (OMIM: 604921) mitogen-activated prot ( 873) 615 59.8 3.9e-08
NP_003609 (OMIM: 604921) mitogen-activated protein ( 894) 615 59.8 3.9e-08
NP_005981 (OMIM: 603919) serine/threonine-protein ( 968) 612 59.7 4.8e-08
NP_001077084 (OMIM: 610040) myosin-IIIb isoform 1 (1314) 602 59.1 9.3e-08
XP_011508957 (OMIM: 610040) PREDICTED: myosin-IIIb (1323) 602 59.1 9.3e-08
NP_620482 (OMIM: 610040) myosin-IIIb isoform 2 [Ho (1341) 602 59.2 9.4e-08
XP_006712362 (OMIM: 610040) PREDICTED: myosin-IIIb (1350) 602 59.2 9.4e-08
XP_016873585 (OMIM: 603166) PREDICTED: mitogen-act ( 584) 592 57.9 9.5e-08
XP_011508956 (OMIM: 610040) PREDICTED: myosin-IIIb (1386) 602 59.2 9.6e-08
XP_011538703 (OMIM: 616563) PREDICTED: STE20-like ( 783) 594 58.3 1e-07
NP_001291672 (OMIM: 616563) STE20-like serine/thre (1204) 598 58.8 1.1e-07
NP_055535 (OMIM: 616563) STE20-like serine/threoni (1235) 598 58.8 1.1e-07
XP_011543505 (OMIM: 603166) PREDICTED: mitogen-act ( 797) 592 58.1 1.1e-07
NP_001294919 (OMIM: 603166) mitogen-activated prot ( 812) 592 58.1 1.1e-07
NP_004570 (OMIM: 603166) mitogen-activated protein ( 820) 592 58.1 1.2e-07
XP_016883522 (OMIM: 604965,614868) PREDICTED: seri ( 388) 575 56.5 1.7e-07
XP_011527322 (OMIM: 604965,614868) PREDICTED: seri ( 404) 575 56.5 1.8e-07
XP_005260590 (OMIM: 604965,614868) PREDICTED: seri ( 462) 575 56.6 1.9e-07
XP_011534679 (OMIM: 604923) PREDICTED: mitogen-act ( 845) 582 57.5 1.9e-07
NP_942089 (OMIM: 604923) mitogen-activated protein ( 846) 582 57.5 1.9e-07
NP_006566 (OMIM: 604923) mitogen-activated protein ( 846) 582 57.5 1.9e-07
XP_006720076 (OMIM: 604923) PREDICTED: mitogen-act ( 846) 582 57.5 1.9e-07
XP_005260588 (OMIM: 604965,614868) PREDICTED: seri ( 478) 575 56.6 2e-07
NP_006273 (OMIM: 604965,614868) serine/threonine-p ( 487) 575 56.6 2e-07
XP_005260587 (OMIM: 604965,614868) PREDICTED: seri ( 503) 575 56.6 2e-07
XP_016883521 (OMIM: 604965,614868) PREDICTED: seri ( 458) 569 56.2 2.6e-07
>>NP_005100 (OMIM: 604046) serine/threonine-protein kina (527 aa)
initn: 3426 init1: 3426 opt: 3426 Z-score: 1341.1 bits: 257.8 E(85289): 5.8e-68
Smith-Waterman score: 3426; 100.0% identity (100.0% similar) in 527 aa overlap (1-527:1-527)
10 20 30 40 50 60
pF1KA1 MSEDSSALPWSINRDDYELQEVIGSGATAVVQAAYCAPKKEKVAIKRINLEKCQTSMDEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MSEDSSALPWSINRDDYELQEVIGSGATAVVQAAYCAPKKEKVAIKRINLEKCQTSMDEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 LKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 STIATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLATGGDITRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 STIATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLATGGDITRN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 KVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 QNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQKDPEKRPTAAELLRHKFFQKAKNKEFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQKDPEKRPTAAELLRHKFFQKAKNKEFL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 QEKTLQRAPTISERAKKVRRVPGSSGRLHKTEDGGWEWSDDEFDEESEEGKAAISQLRSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QEKTLQRAPTISERAKKVRRVPGSSGRLHKTEDGGWEWSDDEFDEESEEGKAAISQLRSP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 RVKESISNSELFPTTDPVGTLLQVPEQISAHLPQPAGQIATQPTQVSLPPTAEPAKTAQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RVKESISNSELFPTTDPVGTLLQVPEQISAHLPQPAGQIATQPTQVSLPPTAEPAKTAQA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 LSSGSGSQETKIPISLVLRLRNSKKELNDIRFEFTPGRDTAEGVSQELISAGLVDGRDLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LSSGSGSQETKIPISLVLRLRNSKKELNDIRFEFTPGRDTAEGVSQELISAGLVDGRDLV
430 440 450 460 470 480
490 500 510 520
pF1KA1 IVAANLQKIVEEPQSNRSVTFKLASGVEGSDIPDDGKLIGFAQLSIS
:::::::::::::::::::::::::::::::::::::::::::::::
NP_005 IVAANLQKIVEEPQSNRSVTFKLASGVEGSDIPDDGKLIGFAQLSIS
490 500 510 520
>>XP_011532633 (OMIM: 604046) PREDICTED: serine/threonin (580 aa)
initn: 3273 init1: 3273 opt: 3273 Z-score: 1282.3 bits: 247.1 E(85289): 1.1e-64
Smith-Waterman score: 3273; 100.0% identity (100.0% similar) in 504 aa overlap (24-527:77-580)
10 20 30 40 50
pF1KA1 MSEDSSALPWSINRDDYELQEVIGSGATAVVQAAYCAPKKEKVAIKRINLEKC
::::::::::::::::::::::::::::::
XP_011 YIQPHWRWRPEAGPRWGVTSAVTSARCVSAGSGATAVVQAAYCAPKKEKVAIKRINLEKC
50 60 70 80 90 100
60 70 80 90 100 110
pF1KA1 QTSMDELLKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIKHIVAKGEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QTSMDELLKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIKHIVAKGEH
110 120 130 140 150 160
120 130 140 150 160 170
pF1KA1 KSGVLDESTIATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSGVLDESTIATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLAT
170 180 190 200 210 220
180 190 200 210 220 230
pF1KA1 GGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKYPPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKYPPM
230 240 250 260 270 280
240 250 260 270 280 290
pF1KA1 KVLMLTLQNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQKDPEKRPTAAELLRHKFFQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVLMLTLQNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQKDPEKRPTAAELLRHKFFQK
290 300 310 320 330 340
300 310 320 330 340 350
pF1KA1 AKNKEFLQEKTLQRAPTISERAKKVRRVPGSSGRLHKTEDGGWEWSDDEFDEESEEGKAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKNKEFLQEKTLQRAPTISERAKKVRRVPGSSGRLHKTEDGGWEWSDDEFDEESEEGKAA
350 360 370 380 390 400
360 370 380 390 400 410
pF1KA1 ISQLRSPRVKESISNSELFPTTDPVGTLLQVPEQISAHLPQPAGQIATQPTQVSLPPTAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISQLRSPRVKESISNSELFPTTDPVGTLLQVPEQISAHLPQPAGQIATQPTQVSLPPTAE
410 420 430 440 450 460
420 430 440 450 460 470
pF1KA1 PAKTAQALSSGSGSQETKIPISLVLRLRNSKKELNDIRFEFTPGRDTAEGVSQELISAGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAKTAQALSSGSGSQETKIPISLVLRLRNSKKELNDIRFEFTPGRDTAEGVSQELISAGL
470 480 490 500 510 520
480 490 500 510 520
pF1KA1 VDGRDLVIVAANLQKIVEEPQSNRSVTFKLASGVEGSDIPDDGKLIGFAQLSIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDGRDLVIVAANLQKIVEEPQSNRSVTFKLASGVEGSDIPDDGKLIGFAQLSIS
530 540 550 560 570 580
>>XP_005265695 (OMIM: 604046) PREDICTED: serine/threonin (460 aa)
initn: 2789 init1: 2789 opt: 2798 Z-score: 1102.2 bits: 213.4 E(85289): 1.2e-54
Smith-Waterman score: 2798; 96.7% identity (98.4% similar) in 450 aa overlap (78-527:15-460)
50 60 70 80 90 100
pF1KA1 INLEKCQTSMDELLKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIKHI
...:.:.. .: : .: ::::::::::
XP_005 MMVGSFANTNHLSRWWSSMVLS--VWRDMGVL--GSVLDIIKHI
10 20 30 40
110 120 130 140 150 160
pF1KA1 VAKGEHKSGVLDESTIATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VAKGEHKSGVLDESTIATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGV
50 60 70 80 90 100
170 180 190 200 210 220
pF1KA1 SAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGAAPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGAAPY
110 120 130 140 150 160
230 240 250 260 270 280
pF1KA1 HKYPPMKVLMLTLQNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQKDPEKRPTAAELLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HKYPPMKVLMLTLQNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQKDPEKRPTAAELLR
170 180 190 200 210 220
290 300 310 320 330 340
pF1KA1 HKFFQKAKNKEFLQEKTLQRAPTISERAKKVRRVPGSSGRLHKTEDGGWEWSDDEFDEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HKFFQKAKNKEFLQEKTLQRAPTISERAKKVRRVPGSSGRLHKTEDGGWEWSDDEFDEES
230 240 250 260 270 280
350 360 370 380 390 400
pF1KA1 EEGKAAISQLRSPRVKESISNSELFPTTDPVGTLLQVPEQISAHLPQPAGQIATQPTQVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEGKAAISQLRSPRVKESISNSELFPTTDPVGTLLQVPEQISAHLPQPAGQIATQPTQVS
290 300 310 320 330 340
410 420 430 440 450 460
pF1KA1 LPPTAEPAKTAQALSSGSGSQETKIPISLVLRLRNSKKELNDIRFEFTPGRDTAEGVSQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LPPTAEPAKTAQALSSGSGSQETKIPISLVLRLRNSKKELNDIRFEFTPGRDTAEGVSQE
350 360 370 380 390 400
470 480 490 500 510 520
pF1KA1 LISAGLVDGRDLVIVAANLQKIVEEPQSNRSVTFKLASGVEGSDIPDDGKLIGFAQLSIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LISAGLVDGRDLVIVAANLQKIVEEPQSNRSVTFKLASGVEGSDIPDDGKLIGFAQLSIS
410 420 430 440 450 460
>>XP_016863090 (OMIM: 604046) PREDICTED: serine/threonin (568 aa)
initn: 2210 init1: 2210 opt: 2224 Z-score: 882.5 bits: 173.1 E(85289): 2.1e-42
Smith-Waterman score: 3167; 97.6% identity (97.6% similar) in 504 aa overlap (24-527:77-568)
10 20 30 40 50
pF1KA1 MSEDSSALPWSINRDDYELQEVIGSGATAVVQAAYCAPKKEKVAIKRINLEKC
::::::::::::::::::::::::::::::
XP_016 YIQPHWRWRPEAGPRWGVTSAVTSARCVSAGSGATAVVQAAYCAPKKEKVAIKRINLEKC
50 60 70 80 90 100
60 70 80 90 100 110
pF1KA1 QTSMDELLKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIKHIVAKGEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTSMDELLKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIKHIVAKGEH
110 120 130 140 150 160
120 130 140 150 160 170
pF1KA1 KSGVLDESTIATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSGVLDESTIATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLAT
170 180 190 200 210 220
180 190 200 210 220 230
pF1KA1 GGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKYPPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKYPPM
230 240 250 260 270 280
240 250 260 270 280 290
pF1KA1 KVLMLTLQNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQKDPEKRPTAAELLRHKFFQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVLMLTLQNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQKDPEKRPTAAELLRHKFFQK
290 300 310 320 330 340
300 310 320 330 340 350
pF1KA1 AKNKEFLQEKTLQRAPTISERAKKVRRVPGSSGRLHKTEDGGWEWSDDEFDEESEEGKAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKNKEFLQEKTLQRAPTISERAKKVRRVPGSSGRLHKTEDGGWEWSDDEFDEESEEGKAA
350 360 370 380 390 400
360 370 380 390 400 410
pF1KA1 ISQLRSPRVKESISNSELFPTTDPVGTLLQVPEQISAHLPQPAGQIATQPTQVSLPPTAE
::::: :::::::::::::::::::::::::::::::::::::::::::
XP_016 ISQLR------------LFPTTDPVGTLLQVPEQISAHLPQPAGQIATQPTQVSLPPTAE
410 420 430 440 450
420 430 440 450 460 470
pF1KA1 PAKTAQALSSGSGSQETKIPISLVLRLRNSKKELNDIRFEFTPGRDTAEGVSQELISAGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAKTAQALSSGSGSQETKIPISLVLRLRNSKKELNDIRFEFTPGRDTAEGVSQELISAGL
460 470 480 490 500 510
480 490 500 510 520
pF1KA1 VDGRDLVIVAANLQKIVEEPQSNRSVTFKLASGVEGSDIPDDGKLIGFAQLSIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDGRDLVIVAANLQKIVEEPQSNRSVTFKLASGVEGSDIPDDGKLIGFAQLSIS
520 530 540 550 560
>>XP_016863091 (OMIM: 604046) PREDICTED: serine/threonin (335 aa)
initn: 2174 init1: 2174 opt: 2174 Z-score: 865.7 bits: 169.2 E(85289): 1.8e-41
Smith-Waterman score: 2174; 100.0% identity (100.0% similar) in 335 aa overlap (193-527:1-335)
170 180 190 200 210 220
pF1KA1 ADFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELAT
::::::::::::::::::::::::::::::
XP_016 MAPEVMEQVRGYDFKADIWSFGITAIELAT
10 20 30
230 240 250 260 270 280
pF1KA1 GAAPYHKYPPMKVLMLTLQNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQKDPEKRPTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAAPYHKYPPMKVLMLTLQNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQKDPEKRPTA
40 50 60 70 80 90
290 300 310 320 330 340
pF1KA1 AELLRHKFFQKAKNKEFLQEKTLQRAPTISERAKKVRRVPGSSGRLHKTEDGGWEWSDDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AELLRHKFFQKAKNKEFLQEKTLQRAPTISERAKKVRRVPGSSGRLHKTEDGGWEWSDDE
100 110 120 130 140 150
350 360 370 380 390 400
pF1KA1 FDEESEEGKAAISQLRSPRVKESISNSELFPTTDPVGTLLQVPEQISAHLPQPAGQIATQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FDEESEEGKAAISQLRSPRVKESISNSELFPTTDPVGTLLQVPEQISAHLPQPAGQIATQ
160 170 180 190 200 210
410 420 430 440 450 460
pF1KA1 PTQVSLPPTAEPAKTAQALSSGSGSQETKIPISLVLRLRNSKKELNDIRFEFTPGRDTAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTQVSLPPTAEPAKTAQALSSGSGSQETKIPISLVLRLRNSKKELNDIRFEFTPGRDTAE
220 230 240 250 260 270
470 480 490 500 510 520
pF1KA1 GVSQELISAGLVDGRDLVIVAANLQKIVEEPQSNRSVTFKLASGVEGSDIPDDGKLIGFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GVSQELISAGLVDGRDLVIVAANLQKIVEEPQSNRSVTFKLASGVEGSDIPDDGKLIGFA
280 290 300 310 320 330
pF1KA1 QLSIS
:::::
XP_016 QLSIS
>>XP_016859303 (OMIM: 607648) PREDICTED: STE20/SPS1-rela (461 aa)
initn: 2101 init1: 2076 opt: 2081 Z-score: 828.9 bits: 162.8 E(85289): 2e-39
Smith-Waterman score: 2081; 80.8% identity (92.0% similar) in 386 aa overlap (5-390:51-428)
10 20 30
pF1KA1 MSEDSSALPWSINRDDYELQEVIGSGATAVVQAA
..:. : : :: ::::::::::::::::::
XP_016 TAAAAAAPAAATAAPAPAAPAAPAPAPAPAAQAVGWPICRDAYELQEVIGSGATAVVQAA
30 40 50 60 70 80
40 50 60 70 80 90
pF1KA1 YCAPKKEKVAIKRINLEKCQTSMDELLKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKL
: :..:.:::::::::::::::::::::::::::: :::.:.:::::::::::::::::
XP_016 LCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKL
90 100 110 120 130 140
100 110 120 130 140 150
pF1KA1 LSGGSVLDIIKHIVAKGEHKSGVLDESTIATILREVLEGLEYLHKNGQIHRDVKAGNILL
:::::.:::::.:: .::::.:::.:. :::::.::::::.:::.:::::::.:::::::
XP_016 LSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILL
150 160 170 180 190 200
160 170 180 190 200 210
pF1KA1 GEDGSVQIADFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFG
::::::::::::::::::::::.::::::::::::::::::::::::::::::::.::::
XP_016 GEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFG
210 220 230 240 250 260
220 230 240 250 260 270
pF1KA1 ITAIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQK
:::::::::::::::::::::::::::::::.:::::.::::.:::::::::..::::::
XP_016 ITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQK
270 280 290 300 310 320
280 290 300 310 320 330
pF1KA1 DPEKRPTAAELLRHKFFQKAKNKEFLQEKTLQRAPTISERAKKVRRVPGSSGRLHKTEDG
:: :::::::::. ::::::::.:.: :: : :.: :..:::::::::::::.:::::::
XP_016 DPSKRPTAAELLKCKFFQKAKNREYLIEKLLTRTPDIAQRAKKVRRVPGSSGHLHKTEDG
330 340 350 360 370 380
340 350 360 370 380 390
pF1KA1 GWEWSDDEFDEESEEGKAAISQLRSPRVKESISNSELFPTTDPVGTLLQVPEQISAHLPQ
:::::::.::.:::::::.:: .: :::: : :. ... .::::..
XP_016 DWEWSDDEMDEKSEEGKAAFSQEKSRRVKEE--NPEIAVSAST------IPEQIQSLSVH
390 400 410 420 430
400 410 420 430 440 450
pF1KA1 PAGQIATQPTQVSLPPTAEPAKTAQALSSGSGSQETKIPISLVLRLRNSKKELNDIRFEF
XP_016 DSQGPPNANEDYREASSCAVNLVLRLRWT
440 450 460
>>XP_016859302 (OMIM: 607648) PREDICTED: STE20/SPS1-rela (535 aa)
initn: 2424 init1: 2076 opt: 2081 Z-score: 828.2 bits: 162.9 E(85289): 2.2e-39
Smith-Waterman score: 2405; 73.9% identity (87.5% similar) in 506 aa overlap (5-509:51-527)
10 20 30
pF1KA1 MSEDSSALPWSINRDDYELQEVIGSGATAVVQAA
..:. : : :: ::::::::::::::::::
XP_016 TAAAAAAPAAATAAPAPAAPAAPAPAPAPAAQAVGWPICRDAYELQEVIGSGATAVVQAA
30 40 50 60 70 80
40 50 60 70 80 90
pF1KA1 YCAPKKEKVAIKRINLEKCQTSMDELLKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKL
: :..:.:::::::::::::::::::::::::::: :::.:.:::::::::::::::::
XP_016 LCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKL
90 100 110 120 130 140
100 110 120 130 140 150
pF1KA1 LSGGSVLDIIKHIVAKGEHKSGVLDESTIATILREVLEGLEYLHKNGQIHRDVKAGNILL
:::::.:::::.:: .::::.:::.:. :::::.::::::.:::.:::::::.:::::::
XP_016 LSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILL
150 160 170 180 190 200
160 170 180 190 200 210
pF1KA1 GEDGSVQIADFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFG
::::::::::::::::::::::.::::::::::::::::::::::::::::::::.::::
XP_016 GEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFG
210 220 230 240 250 260
220 230 240 250 260 270
pF1KA1 ITAIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQK
:::::::::::::::::::::::::::::::.:::::.::::.:::::::::..::::::
XP_016 ITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQK
270 280 290 300 310 320
280 290 300 310 320 330
pF1KA1 DPEKRPTAAELLRHKFFQKAKNKEFLQEKTLQRAPTISERAKKVRRVPGSSGRLHKTEDG
:: :::::::::. ::::::::.:.: :: : :.: :..:::::::::::::.:::::::
XP_016 DPSKRPTAAELLKCKFFQKAKNREYLIEKLLTRTPDIAQRAKKVRRVPGSSGHLHKTEDG
330 340 350 360 370 380
340 350 360 370 380 390
pF1KA1 GWEWSDDEFDEESEEGKAAISQLRSPRVKESISNSELFPTTDPVGTLLQVPEQISAHLPQ
:::::::.::.:::::::.:: .: :::: : :. ... .::::..
XP_016 DWEWSDDEMDEKSEEGKAAFSQEKSRRVKE--ENPEIAVSAS------TIPEQIQS----
390 400 410 420
400 410 420 430 440 450
pF1KA1 PAGQIATQPTQVSLPPTA-EPAKTAQALSSGSGSQETKIPISLVLRLRNSKKELNDIRFE
.... .: ::.: : . :.. . ..::::::::.:::::::::
XP_016 ----LSVHDSQ--GPPNANEDYREASSCA-----------VNLVLRLRNSRKELNDIRFE
430 440 450 460 470
460 470 480 490 500 510
pF1KA1 FTPGRDTAEGVSQELISAGLVDGRDLVIVAANLQKIVEEPQSNRSVTFKLASGVEGSDIP
::::::::.::::::.:::::::.:.:::::::::::..:.. ...:::: .. :
XP_016 FTPGRDTADGVSQELFSAGLVDGHDVVIVAANLQKIVDDPKALKTLTFKLRNSNPGPFLL
480 490 500 510 520 530
520
pF1KA1 DDGKLIGFAQLSIS
XP_016 PKIL
>>NP_037365 (OMIM: 607648) STE20/SPS1-related proline-al (545 aa)
initn: 2537 init1: 2076 opt: 2081 Z-score: 828.1 bits: 162.9 E(85289): 2.2e-39
Smith-Waterman score: 2520; 74.6% identity (88.2% similar) in 524 aa overlap (5-527:51-545)
10 20 30
pF1KA1 MSEDSSALPWSINRDDYELQEVIGSGATAVVQAA
..:. : : :: ::::::::::::::::::
NP_037 TAAAAAAPAAATAAPAPAAPAAPAPAPAPAAQAVGWPICRDAYELQEVIGSGATAVVQAA
30 40 50 60 70 80
40 50 60 70 80 90
pF1KA1 YCAPKKEKVAIKRINLEKCQTSMDELLKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKL
: :..:.:::::::::::::::::::::::::::: :::.:.:::::::::::::::::
NP_037 LCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKL
90 100 110 120 130 140
100 110 120 130 140 150
pF1KA1 LSGGSVLDIIKHIVAKGEHKSGVLDESTIATILREVLEGLEYLHKNGQIHRDVKAGNILL
:::::.:::::.:: .::::.:::.:. :::::.::::::.:::.:::::::.:::::::
NP_037 LSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILL
150 160 170 180 190 200
160 170 180 190 200 210
pF1KA1 GEDGSVQIADFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFG
::::::::::::::::::::::.::::::::::::::::::::::::::::::::.::::
NP_037 GEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFG
210 220 230 240 250 260
220 230 240 250 260 270
pF1KA1 ITAIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQK
:::::::::::::::::::::::::::::::.:::::.::::.:::::::::..::::::
NP_037 ITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQK
270 280 290 300 310 320
280 290 300 310 320 330
pF1KA1 DPEKRPTAAELLRHKFFQKAKNKEFLQEKTLQRAPTISERAKKVRRVPGSSGRLHKTEDG
:: :::::::::. ::::::::.:.: :: : :.: :..:::::::::::::.:::::::
NP_037 DPSKRPTAAELLKCKFFQKAKNREYLIEKLLTRTPDIAQRAKKVRRVPGSSGHLHKTEDG
330 340 350 360 370 380
340 350 360 370 380 390
pF1KA1 GWEWSDDEFDEESEEGKAAISQLRSPRVKESISNSELFPTTDPVGTLLQVPEQISAHLPQ
:::::::.::.:::::::.:: .: :::: : :. ... . ::::..
NP_037 DWEWSDDEMDEKSEEGKAAFSQEKSRRVKE--ENPEIAVSASTI------PEQIQS----
390 400 410 420
400 410 420 430 440 450
pF1KA1 PAGQIATQPTQVSLPPTA-EPAKTAQALSSGSGSQETKIPISLVLRLRNSKKELNDIRFE
.... .: ::.: : . :.. . ..::::::::.:::::::::
NP_037 ----LSVHDSQG--PPNANEDYREASSCA-----------VNLVLRLRNSRKELNDIRFE
430 440 450 460 470
460 470 480 490 500 510
pF1KA1 FTPGRDTAEGVSQELISAGLVDGRDLVIVAANLQKIVEEPQSNRSVTFKLASGVEGSDIP
::::::::.::::::.:::::::.:.:::::::::::..:.. ...::::::: .::.::
NP_037 FTPGRDTADGVSQELFSAGLVDGHDVVIVAANLQKIVDDPKALKTLTFKLASGCDGSEIP
480 490 500 510 520 530
520
pF1KA1 DDGKLIGFAQLSIS
:. :::::::::.:
NP_037 DEVKLIGFAQLSVS
540
>>XP_005246522 (OMIM: 607648) PREDICTED: STE20/SPS1-rela (524 aa)
initn: 2537 init1: 2076 opt: 2077 Z-score: 826.8 bits: 162.6 E(85289): 2.6e-39
Smith-Waterman score: 2465; 73.7% identity (85.1% similar) in 524 aa overlap (5-527:51-524)
10 20 30
pF1KA1 MSEDSSALPWSINRDDYELQEVIGSGATAVVQAA
..:. : : :: ::::::::::::::::::
XP_005 TAAAAAAPAAATAAPAPAAPAAPAPAPAPAAQAVGWPICRDAYELQEVIGSGATAVVQAA
30 40 50 60 70 80
40 50 60 70 80 90
pF1KA1 YCAPKKEKVAIKRINLEKCQTSMDELLKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKL
: :..:.:::::::::::::::::::::::::::: :::.:.:::::::::::::::::
XP_005 LCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKL
90 100 110 120 130 140
100 110 120 130 140 150
pF1KA1 LSGGSVLDIIKHIVAKGEHKSGVLDESTIATILREVLEGLEYLHKNGQIHRDVKAGNILL
:::::.:::::.:: .::::.:::.:. :::::.::::::.:::.:::::::.:::::::
XP_005 LSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILL
150 160 170 180 190 200
160 170 180 190 200 210
pF1KA1 GEDGSVQIADFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFG
::::::::::::::::::::::.::::::::::::::::::::::::::::::::.::::
XP_005 GEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFG
210 220 230 240 250 260
220 230 240 250 260 270
pF1KA1 ITAIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQK
:::::::::::::::::::::::::::::::.:::::.::::.:::::::::..::::::
XP_005 ITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQK
270 280 290 300 310 320
280 290 300 310 320 330
pF1KA1 DPEKRPTAAELLRHKFFQKAKNKEFLQEKTLQRAPTISERAKKVRRVPGSSGRLHKTEDG
:: :::::::::. ::::::::.:.: :: : :.: :..:::::::::::::.:::::::
XP_005 DPSKRPTAAELLKCKFFQKAKNREYLIEKLLTRTPDIAQRAKKVRRVPGSSGHLHKTEDG
330 340 350 360 370 380
340 350 360 370 380 390
pF1KA1 GWEWSDDEFDEESEEGKAAISQLRSPRVKESISNSELFPTTDPVGTLLQVPEQISAHLPQ
:::::::.::.:::::::.:: .: :::: .
XP_005 DWEWSDDEMDEKSEEGKAAFSQEKSRRVKEE----------------------------N
390 400 410
400 410 420 430 440 450
pF1KA1 PAGQIATQPTQVSLPPTA-EPAKTAQALSSGSGSQETKIPISLVLRLRNSKKELNDIRFE
: : ::.: : . :.. . ..::::::::.:::::::::
XP_005 PEG-----------PPNANEDYREASSCA-----------VNLVLRLRNSRKELNDIRFE
420 430 440 450
460 470 480 490 500 510
pF1KA1 FTPGRDTAEGVSQELISAGLVDGRDLVIVAANLQKIVEEPQSNRSVTFKLASGVEGSDIP
::::::::.::::::.:::::::.:.:::::::::::..:.. ...::::::: .::.::
XP_005 FTPGRDTADGVSQELFSAGLVDGHDVVIVAANLQKIVDDPKALKTLTFKLASGCDGSEIP
460 470 480 490 500 510
520
pF1KA1 DDGKLIGFAQLSIS
:. :::::::::.:
XP_005 DEVKLIGFAQLSVS
520
>>XP_016859304 (OMIM: 607648) PREDICTED: STE20/SPS1-rela (443 aa)
initn: 2275 init1: 1814 opt: 1819 Z-score: 729.1 bits: 144.3 E(85289): 7.1e-34
Smith-Waterman score: 2258; 74.4% identity (88.1% similar) in 472 aa overlap (57-527:1-443)
30 40 50 60 70 80
pF1KA1 ATAVVQAAYCAPKKEKVAIKRINLEKCQTSMDELLKEIQAMSQCHHPNIVSYYTSFVVKD
:::::::::::::: :::.:.:::::::::
XP_016 MDELLKEIQAMSQCSHPNVVTYYTSFVVKD
10 20 30
90 100 110 120 130 140
pF1KA1 ELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDESTIATILREVLEGLEYLHKNGQIHRD
:::::::::::::.:::::.:: .::::.:::.:. :::::.::::::.:::.:::::::
XP_016 ELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRD
40 50 60 70 80 90
150 160 170 180 190 200
pF1KA1 VKAGNILLGEDGSVQIADFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDF
.:::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::
XP_016 LKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDF
100 110 120 130 140 150
210 220 230 240 250 260
pF1KA1 KADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGVQDKEMLKKYGKSFRK
:::.:::::::::::::::::::::::::::::::::::.:::::.::::.:::::::::
XP_016 KADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRK
160 170 180 190 200 210
270 280 290 300 310 320
pF1KA1 MISLCLQKDPEKRPTAAELLRHKFFQKAKNKEFLQEKTLQRAPTISERAKKVRRVPGSSG
..:::::::: :::::::::. ::::::::.:.: :: : :.: :..:::::::::::::
XP_016 LLSLCLQKDPSKRPTAAELLKCKFFQKAKNREYLIEKLLTRTPDIAQRAKKVRRVPGSSG
220 230 240 250 260 270
330 340 350 360 370 380
pF1KA1 RLHKTEDGGWEWSDDEFDEESEEGKAAISQLRSPRVKESISNSELFPTTDPVGTLLQVPE
.::::::: :::::::.::.:::::::.:: .: :::: : :. ... . ::
XP_016 HLHKTEDGDWEWSDDEMDEKSEEGKAAFSQEKSRRVKEE--NPEIAVSASTI------PE
280 290 300 310 320
390 400 410 420 430 440
pF1KA1 QISAHLPQPAGQIATQPTQVSLPPTA-EPAKTAQALSSGSGSQETKIPISLVLRLRNSKK
::.. .... .: ::.: : . :.. . ..::::::::.:
XP_016 QIQS--------LSVHDSQ--GPPNANEDYREASSCA-----------VNLVLRLRNSRK
330 340 350 360
450 460 470 480 490 500
pF1KA1 ELNDIRFEFTPGRDTAEGVSQELISAGLVDGRDLVIVAANLQKIVEEPQSNRSVTFKLAS
::::::::::::::::.::::::.:::::::.:.:::::::::::..:.. ...::::::
XP_016 ELNDIRFEFTPGRDTADGVSQELFSAGLVDGHDVVIVAANLQKIVDDPKALKTLTFKLAS
370 380 390 400 410 420
510 520
pF1KA1 GVEGSDIPDDGKLIGFAQLSIS
: .::.:::. :::::::::.:
XP_016 GCDGSEIPDEVKLIGFAQLSVS
430 440
527 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 20:28:22 2016 done: Wed Nov 2 20:28:24 2016
Total Scan time: 10.510 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]