FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1106, 1132 aa 1>>>pF1KA1106 1132 - 1132 aa - 1132 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.2907+/-0.000449; mu= 4.8656+/- 0.028 mean_var=240.1049+/-48.116, 0's: 0 Z-trim(118.4): 90 B-trim: 272 in 1/53 Lambda= 0.082770 statistics sampled from 31153 (31244) to 31153 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.687), E-opt: 0.2 (0.366), width: 16 Scan time: 15.740 The best scores are: opt bits E(85289) NP_055840 (OMIM: 613084,616521) myelin transcripti (1184) 6985 848.3 0 NP_001316777 (OMIM: 613084,616521) myelin transcri (1184) 6985 848.3 0 NP_001316776 (OMIM: 613084,616521) myelin transcri (1184) 6985 848.3 0 XP_016859101 (OMIM: 613084,616521) PREDICTED: myel (1186) 6971 846.6 0 NP_001316773 (OMIM: 613084,616521) myelin transcri (1186) 6971 846.6 0 XP_016859100 (OMIM: 613084,616521) PREDICTED: myel (1186) 6971 846.6 0 NP_001316774 (OMIM: 613084,616521) myelin transcri (1186) 6971 846.6 0 NP_001289981 (OMIM: 613084,616521) myelin transcri (1186) 6971 846.6 0 XP_011508628 (OMIM: 613084,616521) PREDICTED: myel (1188) 6957 845.0 0 XP_016859107 (OMIM: 613084,616521) PREDICTED: myel (1146) 6691 813.2 0 NP_001316775 (OMIM: 613084,616521) myelin transcri (1146) 6691 813.2 0 XP_016859105 (OMIM: 613084,616521) PREDICTED: myel (1148) 6677 811.5 0 NP_001316778 (OMIM: 613084,616521) myelin transcri (1148) 6677 811.5 0 NP_001316780 (OMIM: 613084,616521) myelin transcri (1143) 6675 811.3 0 NP_001316781 (OMIM: 613084,616521) myelin transcri (1143) 6675 811.3 0 XP_016859104 (OMIM: 613084,616521) PREDICTED: myel (1150) 6663 809.8 0 XP_016859111 (OMIM: 613084,616521) PREDICTED: myel ( 924) 5103 623.5 1.8e-177 XP_011508634 (OMIM: 613084,616521) PREDICTED: myel ( 926) 5086 621.5 7.5e-177 XP_011508627 (OMIM: 613084,616521) PREDICTED: myel (1207) 5001 611.4 1e-173 XP_016859095 (OMIM: 613084,616521) PREDICTED: myel (1207) 5001 611.4 1e-173 XP_016859096 (OMIM: 613084,616521) PREDICTED: myel (1207) 5001 611.4 1e-173 XP_011508630 (OMIM: 613084,616521) PREDICTED: myel (1169) 4994 610.5 1.8e-173 XP_011508626 (OMIM: 613084,616521) PREDICTED: myel (1207) 4994 610.6 1.9e-173 XP_016859109 (OMIM: 613084,616521) PREDICTED: myel (1111) 4987 609.7 3.1e-173 XP_011508629 (OMIM: 613084,616521) PREDICTED: myel (1171) 4987 609.7 3.3e-173 XP_011508620 (OMIM: 613084,616521) PREDICTED: myel (1209) 4987 609.7 3.3e-173 XP_011508624 (OMIM: 613084,616521) PREDICTED: myel (1209) 4987 609.7 3.3e-173 XP_016859094 (OMIM: 613084,616521) PREDICTED: myel (1209) 4987 609.7 3.3e-173 XP_011508625 (OMIM: 613084,616521) PREDICTED: myel (1209) 4987 609.7 3.3e-173 XP_016859093 (OMIM: 613084,616521) PREDICTED: myel (1209) 4987 609.7 3.3e-173 XP_011508623 (OMIM: 613084,616521) PREDICTED: myel (1209) 4987 609.7 3.3e-173 XP_011508621 (OMIM: 613084,616521) PREDICTED: myel (1209) 4987 609.7 3.3e-173 XP_011508622 (OMIM: 613084,616521) PREDICTED: myel (1209) 4987 609.7 3.3e-173 XP_016859097 (OMIM: 613084,616521) PREDICTED: myel (1198) 4968 607.4 1.6e-172 XP_016859110 (OMIM: 613084,616521) PREDICTED: myel ( 945) 4952 605.5 5e-172 XP_011508633 (OMIM: 613084,616521) PREDICTED: myel ( 947) 4952 605.5 5e-172 NP_004526 (OMIM: 600379) myelin transcription fact (1121) 2910 361.7 1.4e-98 XP_016869563 (OMIM: 617155) PREDICTED: suppression (1018) 2254 283.3 5.1e-75 XP_016869561 (OMIM: 617155) PREDICTED: suppression (1018) 2254 283.3 5.1e-75 XP_016869562 (OMIM: 617155) PREDICTED: suppression (1018) 2254 283.3 5.1e-75 XP_011515943 (OMIM: 617155) PREDICTED: suppression (1012) 2249 282.7 7.7e-75 XP_016869569 (OMIM: 617155) PREDICTED: suppression (1012) 2249 282.7 7.7e-75 XP_016869566 (OMIM: 617155) PREDICTED: suppression (1012) 2249 282.7 7.7e-75 XP_016869564 (OMIM: 617155) PREDICTED: suppression (1012) 2249 282.7 7.7e-75 XP_016869568 (OMIM: 617155) PREDICTED: suppression (1012) 2249 282.7 7.7e-75 XP_016869565 (OMIM: 617155) PREDICTED: suppression (1012) 2249 282.7 7.7e-75 XP_016869567 (OMIM: 617155) PREDICTED: suppression (1012) 2249 282.7 7.7e-75 XP_011515935 (OMIM: 617155) PREDICTED: suppression (1047) 2249 282.7 7.9e-75 XP_016869537 (OMIM: 617155) PREDICTED: suppression (1047) 2249 282.7 7.9e-75 XP_016869536 (OMIM: 617155) PREDICTED: suppression (1047) 2249 282.7 7.9e-75 >>NP_055840 (OMIM: 613084,616521) myelin transcription f (1184 aa) initn: 6955 init1: 6955 opt: 6985 Z-score: 4520.1 bits: 848.3 E(85289): 0 Smith-Waterman score: 7431; 95.5% identity (95.5% similar) in 1164 aa overlap (21-1132:21-1184) 10 20 30 40 50 60 pF1KA1 MEVDTEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKK :::::::::::::::::::::::::::::::::::::::: NP_055 MEVDTEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKK 10 20 30 40 50 60 70 80 90 100 pF1KA1 RKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEE----------- ::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 RKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDE 70 80 90 100 110 120 110 120 pF1KA1 -----------------------------------------EEEEEENEDHQMNCHNTRI ::::::::::::::::::: NP_055 DEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRI 130 140 150 160 170 180 130 140 150 160 170 180 pF1KA1 MQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKN 190 200 210 220 230 240 190 200 210 220 230 240 pF1KA1 ENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSENMNDRNYADSMSQQDSRNMNYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSENMNDRNYADSMSQQDSRNMNYV 250 260 270 280 290 300 250 260 270 280 290 300 pF1KA1 MLGKPMNNGLMEKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQERNPQQNMNIRQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MLGKPMNNGLMEKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQERNPQQNMNIRQH 310 320 330 340 350 360 310 320 330 340 350 360 pF1KA1 VRPEEDFPGRTPDRNYSDMLNLMRLEEQLSPRSRVFASCAKEDGCHERDDDTTSVNSDRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VRPEEDFPGRTPDRNYSDMLNLMRLEEQLSPRSRVFASCAKEDGCHERDDDTTSVNSDRS 370 380 390 400 410 420 370 380 390 400 410 420 pF1KA1 EEVFDMTKGNLTLLEKAIALETERAKAMREKMAMEAGRRDNMRSYEDQSPRQLPGEDRKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EEVFDMTKGNLTLLEKAIALETERAKAMREKMAMEAGRRDNMRSYEDQSPRQLPGEDRKP 430 440 450 460 470 480 430 440 450 460 470 480 pF1KA1 KSSDSHVKKPYYDPSRTEKKESKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRVPPEILA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KSSDSHVKKPYYDPSRTEKKESKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRVPPEILA 490 500 510 520 530 540 490 500 510 520 530 540 pF1KA1 MHESVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSSQASD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MHESVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSSQASD 550 560 570 580 590 600 550 560 570 580 590 600 pF1KA1 RVLRPMCFVKQLEIPQYGYRNNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRAIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 RVLRPMCFVKQLEIPQYGYRNNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRAIA 610 620 630 640 650 660 610 620 630 640 650 660 pF1KA1 PKVQTRDISPKGYDDAKRYCKDPSPSSSSTSSYAPSSSSNLSCGGGSSASSTCSKSSFDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PKVQTRDISPKGYDDAKRYCKDPSPSSSSTSSYAPSSSSNLSCGGGSSASSTCSKSSFDY 670 680 690 700 710 720 670 680 690 700 710 720 pF1KA1 THDMEAAHMAATAILNLSTRCREMPQNLSTKPQDLCATRNPDMEVDENGTLDLSMNKQRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 THDMEAAHMAATAILNLSTRCREMPQNLSTKPQDLCATRNPDMEVDENGTLDLSMNKQRP 730 740 750 760 770 780 730 740 750 760 770 780 pF1KA1 RDSCCPILTPLEPMSPQQQAVMNNRCFQLGEGDCWDLPVDYTKMKPRRIDEDESKDITPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 RDSCCPILTPLEPMSPQQQAVMNNRCFQLGEGDCWDLPVDYTKMKPRRIDEDESKDITPE 790 800 810 820 830 840 790 800 810 820 830 840 pF1KA1 DLDPFQEALEERRYPGEVTIPSPKPKYPQCKESKKDLITLSGCPLADKSIRSMLATSSQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 DLDPFQEALEERRYPGEVTIPSPKPKYPQCKESKKDLITLSGCPLADKSIRSMLATSSQE 850 860 870 880 890 900 850 860 870 880 890 900 pF1KA1 LKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCDGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCDGQ 910 920 930 940 950 960 910 920 930 940 950 960 pF1KA1 GHITGKYASHRSASGCPLAAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSGSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GHITGKYASHRSASGCPLAAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSGSF 970 980 990 1000 1010 1020 970 980 990 1000 1010 1020 pF1KA1 LTHRSLSGCPRATSAMKKAKLSGEQMLTIKQRASNGIENDEEIKQLDEEIKELNESNSQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LTHRSLSGCPRATSAMKKAKLSGEQMLTIKQRASNGIENDEEIKQLDEEIKELNESNSQM 1030 1040 1050 1060 1070 1080 1030 1040 1050 1060 1070 1080 pF1KA1 EADMIKLRTQITTMESNLKTIEEENKVIEQQNESLLHELANLSQSLIHSLANIQLPHMDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EADMIKLRTQITTMESNLKTIEEENKVIEQQNESLLHELANLSQSLIHSLANIQLPHMDP 1090 1100 1110 1120 1130 1140 1090 1100 1110 1120 1130 pF1KA1 INEQNFDAYVTTLTEMYTNQDRYQSPENKALLENIKQAVRGIQV :::::::::::::::::::::::::::::::::::::::::::: NP_055 INEQNFDAYVTTLTEMYTNQDRYQSPENKALLENIKQAVRGIQV 1150 1160 1170 1180 >>NP_001316777 (OMIM: 613084,616521) myelin transcriptio (1184 aa) initn: 6955 init1: 6955 opt: 6985 Z-score: 4520.1 bits: 848.3 E(85289): 0 Smith-Waterman score: 7431; 95.5% identity (95.5% similar) in 1164 aa overlap (21-1132:21-1184) 10 20 30 40 50 60 pF1KA1 MEVDTEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKK :::::::::::::::::::::::::::::::::::::::: NP_001 MEVDTEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKK 10 20 30 40 50 60 70 80 90 100 pF1KA1 RKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEE----------- ::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDE 70 80 90 100 110 120 110 120 pF1KA1 -----------------------------------------EEEEEENEDHQMNCHNTRI ::::::::::::::::::: NP_001 DEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRI 130 140 150 160 170 180 130 140 150 160 170 180 pF1KA1 MQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKN 190 200 210 220 230 240 190 200 210 220 230 240 pF1KA1 ENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSENMNDRNYADSMSQQDSRNMNYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSENMNDRNYADSMSQQDSRNMNYV 250 260 270 280 290 300 250 260 270 280 290 300 pF1KA1 MLGKPMNNGLMEKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQERNPQQNMNIRQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLGKPMNNGLMEKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQERNPQQNMNIRQH 310 320 330 340 350 360 310 320 330 340 350 360 pF1KA1 VRPEEDFPGRTPDRNYSDMLNLMRLEEQLSPRSRVFASCAKEDGCHERDDDTTSVNSDRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VRPEEDFPGRTPDRNYSDMLNLMRLEEQLSPRSRVFASCAKEDGCHERDDDTTSVNSDRS 370 380 390 400 410 420 370 380 390 400 410 420 pF1KA1 EEVFDMTKGNLTLLEKAIALETERAKAMREKMAMEAGRRDNMRSYEDQSPRQLPGEDRKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEVFDMTKGNLTLLEKAIALETERAKAMREKMAMEAGRRDNMRSYEDQSPRQLPGEDRKP 430 440 450 460 470 480 430 440 450 460 470 480 pF1KA1 KSSDSHVKKPYYDPSRTEKKESKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRVPPEILA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KSSDSHVKKPYYDPSRTEKKESKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRVPPEILA 490 500 510 520 530 540 490 500 510 520 530 540 pF1KA1 MHESVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSSQASD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MHESVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSSQASD 550 560 570 580 590 600 550 560 570 580 590 600 pF1KA1 RVLRPMCFVKQLEIPQYGYRNNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRAIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RVLRPMCFVKQLEIPQYGYRNNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRAIA 610 620 630 640 650 660 610 620 630 640 650 660 pF1KA1 PKVQTRDISPKGYDDAKRYCKDPSPSSSSTSSYAPSSSSNLSCGGGSSASSTCSKSSFDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PKVQTRDISPKGYDDAKRYCKDPSPSSSSTSSYAPSSSSNLSCGGGSSASSTCSKSSFDY 670 680 690 700 710 720 670 680 690 700 710 720 pF1KA1 THDMEAAHMAATAILNLSTRCREMPQNLSTKPQDLCATRNPDMEVDENGTLDLSMNKQRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 THDMEAAHMAATAILNLSTRCREMPQNLSTKPQDLCATRNPDMEVDENGTLDLSMNKQRP 730 740 750 760 770 780 730 740 750 760 770 780 pF1KA1 RDSCCPILTPLEPMSPQQQAVMNNRCFQLGEGDCWDLPVDYTKMKPRRIDEDESKDITPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RDSCCPILTPLEPMSPQQQAVMNNRCFQLGEGDCWDLPVDYTKMKPRRIDEDESKDITPE 790 800 810 820 830 840 790 800 810 820 830 840 pF1KA1 DLDPFQEALEERRYPGEVTIPSPKPKYPQCKESKKDLITLSGCPLADKSIRSMLATSSQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLDPFQEALEERRYPGEVTIPSPKPKYPQCKESKKDLITLSGCPLADKSIRSMLATSSQE 850 860 870 880 890 900 850 860 870 880 890 900 pF1KA1 LKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCDGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCDGQ 910 920 930 940 950 960 910 920 930 940 950 960 pF1KA1 GHITGKYASHRSASGCPLAAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSGSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GHITGKYASHRSASGCPLAAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSGSF 970 980 990 1000 1010 1020 970 980 990 1000 1010 1020 pF1KA1 LTHRSLSGCPRATSAMKKAKLSGEQMLTIKQRASNGIENDEEIKQLDEEIKELNESNSQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LTHRSLSGCPRATSAMKKAKLSGEQMLTIKQRASNGIENDEEIKQLDEEIKELNESNSQM 1030 1040 1050 1060 1070 1080 1030 1040 1050 1060 1070 1080 pF1KA1 EADMIKLRTQITTMESNLKTIEEENKVIEQQNESLLHELANLSQSLIHSLANIQLPHMDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EADMIKLRTQITTMESNLKTIEEENKVIEQQNESLLHELANLSQSLIHSLANIQLPHMDP 1090 1100 1110 1120 1130 1140 1090 1100 1110 1120 1130 pF1KA1 INEQNFDAYVTTLTEMYTNQDRYQSPENKALLENIKQAVRGIQV :::::::::::::::::::::::::::::::::::::::::::: NP_001 INEQNFDAYVTTLTEMYTNQDRYQSPENKALLENIKQAVRGIQV 1150 1160 1170 1180 >>NP_001316776 (OMIM: 613084,616521) myelin transcriptio (1184 aa) initn: 6955 init1: 6955 opt: 6985 Z-score: 4520.1 bits: 848.3 E(85289): 0 Smith-Waterman score: 7431; 95.5% identity (95.5% similar) in 1164 aa overlap (21-1132:21-1184) 10 20 30 40 50 60 pF1KA1 MEVDTEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKK :::::::::::::::::::::::::::::::::::::::: NP_001 MEVDTEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKK 10 20 30 40 50 60 70 80 90 100 pF1KA1 RKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEE----------- ::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDE 70 80 90 100 110 120 110 120 pF1KA1 -----------------------------------------EEEEEENEDHQMNCHNTRI ::::::::::::::::::: NP_001 DEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRI 130 140 150 160 170 180 130 140 150 160 170 180 pF1KA1 MQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKN 190 200 210 220 230 240 190 200 210 220 230 240 pF1KA1 ENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSENMNDRNYADSMSQQDSRNMNYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSENMNDRNYADSMSQQDSRNMNYV 250 260 270 280 290 300 250 260 270 280 290 300 pF1KA1 MLGKPMNNGLMEKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQERNPQQNMNIRQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLGKPMNNGLMEKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQERNPQQNMNIRQH 310 320 330 340 350 360 310 320 330 340 350 360 pF1KA1 VRPEEDFPGRTPDRNYSDMLNLMRLEEQLSPRSRVFASCAKEDGCHERDDDTTSVNSDRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VRPEEDFPGRTPDRNYSDMLNLMRLEEQLSPRSRVFASCAKEDGCHERDDDTTSVNSDRS 370 380 390 400 410 420 370 380 390 400 410 420 pF1KA1 EEVFDMTKGNLTLLEKAIALETERAKAMREKMAMEAGRRDNMRSYEDQSPRQLPGEDRKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEVFDMTKGNLTLLEKAIALETERAKAMREKMAMEAGRRDNMRSYEDQSPRQLPGEDRKP 430 440 450 460 470 480 430 440 450 460 470 480 pF1KA1 KSSDSHVKKPYYDPSRTEKKESKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRVPPEILA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KSSDSHVKKPYYDPSRTEKKESKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRVPPEILA 490 500 510 520 530 540 490 500 510 520 530 540 pF1KA1 MHESVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSSQASD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MHESVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSSQASD 550 560 570 580 590 600 550 560 570 580 590 600 pF1KA1 RVLRPMCFVKQLEIPQYGYRNNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRAIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RVLRPMCFVKQLEIPQYGYRNNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRAIA 610 620 630 640 650 660 610 620 630 640 650 660 pF1KA1 PKVQTRDISPKGYDDAKRYCKDPSPSSSSTSSYAPSSSSNLSCGGGSSASSTCSKSSFDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PKVQTRDISPKGYDDAKRYCKDPSPSSSSTSSYAPSSSSNLSCGGGSSASSTCSKSSFDY 670 680 690 700 710 720 670 680 690 700 710 720 pF1KA1 THDMEAAHMAATAILNLSTRCREMPQNLSTKPQDLCATRNPDMEVDENGTLDLSMNKQRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 THDMEAAHMAATAILNLSTRCREMPQNLSTKPQDLCATRNPDMEVDENGTLDLSMNKQRP 730 740 750 760 770 780 730 740 750 760 770 780 pF1KA1 RDSCCPILTPLEPMSPQQQAVMNNRCFQLGEGDCWDLPVDYTKMKPRRIDEDESKDITPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RDSCCPILTPLEPMSPQQQAVMNNRCFQLGEGDCWDLPVDYTKMKPRRIDEDESKDITPE 790 800 810 820 830 840 790 800 810 820 830 840 pF1KA1 DLDPFQEALEERRYPGEVTIPSPKPKYPQCKESKKDLITLSGCPLADKSIRSMLATSSQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLDPFQEALEERRYPGEVTIPSPKPKYPQCKESKKDLITLSGCPLADKSIRSMLATSSQE 850 860 870 880 890 900 850 860 870 880 890 900 pF1KA1 LKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCDGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCDGQ 910 920 930 940 950 960 910 920 930 940 950 960 pF1KA1 GHITGKYASHRSASGCPLAAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSGSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GHITGKYASHRSASGCPLAAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSGSF 970 980 990 1000 1010 1020 970 980 990 1000 1010 1020 pF1KA1 LTHRSLSGCPRATSAMKKAKLSGEQMLTIKQRASNGIENDEEIKQLDEEIKELNESNSQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LTHRSLSGCPRATSAMKKAKLSGEQMLTIKQRASNGIENDEEIKQLDEEIKELNESNSQM 1030 1040 1050 1060 1070 1080 1030 1040 1050 1060 1070 1080 pF1KA1 EADMIKLRTQITTMESNLKTIEEENKVIEQQNESLLHELANLSQSLIHSLANIQLPHMDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EADMIKLRTQITTMESNLKTIEEENKVIEQQNESLLHELANLSQSLIHSLANIQLPHMDP 1090 1100 1110 1120 1130 1140 1090 1100 1110 1120 1130 pF1KA1 INEQNFDAYVTTLTEMYTNQDRYQSPENKALLENIKQAVRGIQV :::::::::::::::::::::::::::::::::::::::::::: NP_001 INEQNFDAYVTTLTEMYTNQDRYQSPENKALLENIKQAVRGIQV 1150 1160 1170 1180 >>XP_016859101 (OMIM: 613084,616521) PREDICTED: myelin t (1186 aa) initn: 7528 init1: 6368 opt: 6971 Z-score: 4511.0 bits: 846.6 E(85289): 0 Smith-Waterman score: 7417; 95.4% identity (95.4% similar) in 1166 aa overlap (21-1132:21-1186) 10 20 30 40 50 60 pF1KA1 MEVDTEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKK :::::::::::::::::::::::::::::::::::::::: XP_016 MEVDTEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKK 10 20 30 40 50 60 70 80 90 100 pF1KA1 RKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEE----------- ::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDE 70 80 90 100 110 120 110 120 pF1KA1 -----------------------------------------EEEEEENEDHQMNCHNTRI ::::::::::::::::::: XP_016 DEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRI 130 140 150 160 170 180 130 140 150 160 170 180 pF1KA1 MQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKN 190 200 210 220 230 240 190 200 210 220 230 240 pF1KA1 ENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSENMNDRNYADSMSQQDSRNMNYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSENMNDRNYADSMSQQDSRNMNYV 250 260 270 280 290 300 250 260 270 280 290 300 pF1KA1 MLGKPMNNGLMEKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQERNPQQNMNIRQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLGKPMNNGLMEKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQERNPQQNMNIRQH 310 320 330 340 350 360 310 320 330 340 350 360 pF1KA1 VRPEEDFPGRTPDRNYSDMLNLMRLEEQLSPRSRVFASCAKEDGCHERDDDTTSVNSDRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VRPEEDFPGRTPDRNYSDMLNLMRLEEQLSPRSRVFASCAKEDGCHERDDDTTSVNSDRS 370 380 390 400 410 420 370 380 390 400 410 420 pF1KA1 EEVFDMTKGNLTLLEKAIALETERAKAMREKMAMEAGRRDNMRSYEDQSPRQLPGEDRKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEVFDMTKGNLTLLEKAIALETERAKAMREKMAMEAGRRDNMRSYEDQSPRQLPGEDRKP 430 440 450 460 470 480 430 440 450 460 470 480 pF1KA1 KSSDSHVKKPYYDPSRTEKKESKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRVPPEILA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSSDSHVKKPYYDPSRTEKKESKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRVPPEILA 490 500 510 520 530 540 490 500 510 520 530 540 pF1KA1 MHESVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSSQASD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MHESVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSSQASD 550 560 570 580 590 600 550 560 570 580 590 600 pF1KA1 RVLRPMCFVKQLEIPQYGYRNNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRAIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RVLRPMCFVKQLEIPQYGYRNNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRAIA 610 620 630 640 650 660 610 620 630 640 650 660 pF1KA1 PKVQTRDISPKGYDDAKRYCKDPSPSSSSTSSYAPSSSSNLSCGGGSSASSTCSKSSFDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PKVQTRDISPKGYDDAKRYCKDPSPSSSSTSSYAPSSSSNLSCGGGSSASSTCSKSSFDY 670 680 690 700 710 720 670 680 690 700 710 720 pF1KA1 THDMEAAHMAATAILNLSTRCREMPQNLSTKPQDLCATRNPDMEVDENGTLDLSMNKQRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 THDMEAAHMAATAILNLSTRCREMPQNLSTKPQDLCATRNPDMEVDENGTLDLSMNKQRP 730 740 750 760 770 780 730 740 750 760 770 780 pF1KA1 RDSCCPILTPLEPMSPQQQAVMNNRCFQLGEGDCWDLPVDYTKMKPRRIDEDESKDITPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDSCCPILTPLEPMSPQQQAVMNNRCFQLGEGDCWDLPVDYTKMKPRRIDEDESKDITPE 790 800 810 820 830 840 790 800 810 820 830 840 pF1KA1 DLDPFQEALEERRYPGEVTIPSPKPKYPQCKESKKDLITLSGCPLADKSIRSMLATSSQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLDPFQEALEERRYPGEVTIPSPKPKYPQCKESKKDLITLSGCPLADKSIRSMLATSSQE 850 860 870 880 890 900 850 860 870 880 890 900 pF1KA1 LKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCDGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCDGQ 910 920 930 940 950 960 910 920 930 940 950 960 pF1KA1 GHITGKYASHRSASGCPLAAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSGSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GHITGKYASHRSASGCPLAAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSGSF 970 980 990 1000 1010 1020 970 980 990 1000 1010 1020 pF1KA1 LTHRSLSGCPRATSAMKKAKLSGEQMLTIKQRASNGIENDEEIKQLDEEIKELNESNSQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTHRSLSGCPRATSAMKKAKLSGEQMLTIKQRASNGIENDEEIKQLDEEIKELNESNSQM 1030 1040 1050 1060 1070 1080 1030 1040 1050 1060 1070 1080 pF1KA1 EADMIKLRTQ--ITTMESNLKTIEEENKVIEQQNESLLHELANLSQSLIHSLANIQLPHM :::::::::: :::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EADMIKLRTQVTITTMESNLKTIEEENKVIEQQNESLLHELANLSQSLIHSLANIQLPHM 1090 1100 1110 1120 1130 1140 1090 1100 1110 1120 1130 pF1KA1 DPINEQNFDAYVTTLTEMYTNQDRYQSPENKALLENIKQAVRGIQV :::::::::::::::::::::::::::::::::::::::::::::: XP_016 DPINEQNFDAYVTTLTEMYTNQDRYQSPENKALLENIKQAVRGIQV 1150 1160 1170 1180 >>NP_001316773 (OMIM: 613084,616521) myelin transcriptio (1186 aa) initn: 5495 init1: 4725 opt: 6971 Z-score: 4511.0 bits: 846.6 E(85289): 0 Smith-Waterman score: 7406; 95.4% identity (95.4% similar) in 1164 aa overlap (23-1132:23-1186) 10 20 30 40 50 60 pF1KA1 MEVDTEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKK :::::::::::::::::::::::::::::::::::::: NP_001 MEVDTEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKK 10 20 30 40 50 60 70 80 90 100 pF1KA1 RKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEE----------- ::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDE 70 80 90 100 110 120 110 120 pF1KA1 -----------------------------------------EEEEEENEDHQMNCHNTRI ::::::::::::::::::: NP_001 DEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRI 130 140 150 160 170 180 130 140 150 160 170 180 pF1KA1 MQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKN 190 200 210 220 230 240 190 200 210 220 230 240 pF1KA1 ENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSENMNDRNYADSMSQQDSRNMNYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSENMNDRNYADSMSQQDSRNMNYV 250 260 270 280 290 300 250 260 270 280 290 300 pF1KA1 MLGKPMNNGLMEKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQERNPQQNMNIRQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLGKPMNNGLMEKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQERNPQQNMNIRQH 310 320 330 340 350 360 310 320 330 340 350 360 pF1KA1 VRPEEDFPGRTPDRNYSDMLNLMRLEEQLSPRSRVFASCAKEDGCHERDDDTTSVNSDRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VRPEEDFPGRTPDRNYSDMLNLMRLEEQLSPRSRVFASCAKEDGCHERDDDTTSVNSDRS 370 380 390 400 410 420 370 380 390 400 410 420 pF1KA1 EEVFDMTKGNLTLLEKAIALETERAKAMREKMAMEAGRRDNMRSYEDQSPRQLPGEDRKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEVFDMTKGNLTLLEKAIALETERAKAMREKMAMEAGRRDNMRSYEDQSPRQLPGEDRKP 430 440 450 460 470 480 430 440 450 460 470 480 pF1KA1 KSSDSHVKKPYY--DPSRTEKKESKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRVPPEI :::::::::::: :::::::::::::::::::::::::::::::::::::::::::::: NP_001 KSSDSHVKKPYYGKDPSRTEKKESKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRVPPEI 490 500 510 520 530 540 490 500 510 520 530 540 pF1KA1 LAMHESVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSSQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAMHESVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSSQA 550 560 570 580 590 600 550 560 570 580 590 600 pF1KA1 SDRVLRPMCFVKQLEIPQYGYRNNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SDRVLRPMCFVKQLEIPQYGYRNNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRA 610 620 630 640 650 660 610 620 630 640 650 660 pF1KA1 IAPKVQTRDISPKGYDDAKRYCKDPSPSSSSTSSYAPSSSSNLSCGGGSSASSTCSKSSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IAPKVQTRDISPKGYDDAKRYCKDPSPSSSSTSSYAPSSSSNLSCGGGSSASSTCSKSSF 670 680 690 700 710 720 670 680 690 700 710 720 pF1KA1 DYTHDMEAAHMAATAILNLSTRCREMPQNLSTKPQDLCATRNPDMEVDENGTLDLSMNKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DYTHDMEAAHMAATAILNLSTRCREMPQNLSTKPQDLCATRNPDMEVDENGTLDLSMNKQ 730 740 750 760 770 780 730 740 750 760 770 780 pF1KA1 RPRDSCCPILTPLEPMSPQQQAVMNNRCFQLGEGDCWDLPVDYTKMKPRRIDEDESKDIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RPRDSCCPILTPLEPMSPQQQAVMNNRCFQLGEGDCWDLPVDYTKMKPRRIDEDESKDIT 790 800 810 820 830 840 790 800 810 820 830 840 pF1KA1 PEDLDPFQEALEERRYPGEVTIPSPKPKYPQCKESKKDLITLSGCPLADKSIRSMLATSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PEDLDPFQEALEERRYPGEVTIPSPKPKYPQCKESKKDLITLSGCPLADKSIRSMLATSS 850 860 870 880 890 900 850 860 870 880 890 900 pF1KA1 QELKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QELKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCD 910 920 930 940 950 960 910 920 930 940 950 960 pF1KA1 GQGHITGKYASHRSASGCPLAAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GQGHITGKYASHRSASGCPLAAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSG 970 980 990 1000 1010 1020 970 980 990 1000 1010 1020 pF1KA1 SFLTHRSLSGCPRATSAMKKAKLSGEQMLTIKQRASNGIENDEEIKQLDEEIKELNESNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SFLTHRSLSGCPRATSAMKKAKLSGEQMLTIKQRASNGIENDEEIKQLDEEIKELNESNS 1030 1040 1050 1060 1070 1080 1030 1040 1050 1060 1070 1080 pF1KA1 QMEADMIKLRTQITTMESNLKTIEEENKVIEQQNESLLHELANLSQSLIHSLANIQLPHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QMEADMIKLRTQITTMESNLKTIEEENKVIEQQNESLLHELANLSQSLIHSLANIQLPHM 1090 1100 1110 1120 1130 1140 1090 1100 1110 1120 1130 pF1KA1 DPINEQNFDAYVTTLTEMYTNQDRYQSPENKALLENIKQAVRGIQV :::::::::::::::::::::::::::::::::::::::::::::: NP_001 DPINEQNFDAYVTTLTEMYTNQDRYQSPENKALLENIKQAVRGIQV 1150 1160 1170 1180 >>XP_016859100 (OMIM: 613084,616521) PREDICTED: myelin t (1186 aa) initn: 7528 init1: 6368 opt: 6971 Z-score: 4511.0 bits: 846.6 E(85289): 0 Smith-Waterman score: 7417; 95.4% identity (95.4% similar) in 1166 aa overlap (21-1132:21-1186) 10 20 30 40 50 60 pF1KA1 MEVDTEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKK :::::::::::::::::::::::::::::::::::::::: XP_016 MEVDTEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKK 10 20 30 40 50 60 70 80 90 100 pF1KA1 RKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEE----------- ::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDE 70 80 90 100 110 120 110 120 pF1KA1 -----------------------------------------EEEEEENEDHQMNCHNTRI ::::::::::::::::::: XP_016 DEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRI 130 140 150 160 170 180 130 140 150 160 170 180 pF1KA1 MQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKN 190 200 210 220 230 240 190 200 210 220 230 240 pF1KA1 ENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSENMNDRNYADSMSQQDSRNMNYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSENMNDRNYADSMSQQDSRNMNYV 250 260 270 280 290 300 250 260 270 280 290 300 pF1KA1 MLGKPMNNGLMEKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQERNPQQNMNIRQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLGKPMNNGLMEKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQERNPQQNMNIRQH 310 320 330 340 350 360 310 320 330 340 350 360 pF1KA1 VRPEEDFPGRTPDRNYSDMLNLMRLEEQLSPRSRVFASCAKEDGCHERDDDTTSVNSDRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VRPEEDFPGRTPDRNYSDMLNLMRLEEQLSPRSRVFASCAKEDGCHERDDDTTSVNSDRS 370 380 390 400 410 420 370 380 390 400 410 420 pF1KA1 EEVFDMTKGNLTLLEKAIALETERAKAMREKMAMEAGRRDNMRSYEDQSPRQLPGEDRKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEVFDMTKGNLTLLEKAIALETERAKAMREKMAMEAGRRDNMRSYEDQSPRQLPGEDRKP 430 440 450 460 470 480 430 440 450 460 470 480 pF1KA1 KSSDSHVKKPYYDPSRTEKKESKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRVPPEILA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSSDSHVKKPYYDPSRTEKKESKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRVPPEILA 490 500 510 520 530 540 490 500 510 520 530 540 pF1KA1 MHESVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSSQASD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MHESVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSSQASD 550 560 570 580 590 600 550 560 570 580 590 600 pF1KA1 RVLRPMCFVKQLEIPQYGYRNNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRAIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RVLRPMCFVKQLEIPQYGYRNNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRAIA 610 620 630 640 650 660 610 620 630 640 650 660 pF1KA1 PKVQTRDISPKGYDDAKRYCKDPSPSSSSTSSYAPSSSSNLSCGGGSSASSTCSKSSFDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PKVQTRDISPKGYDDAKRYCKDPSPSSSSTSSYAPSSSSNLSCGGGSSASSTCSKSSFDY 670 680 690 700 710 720 670 680 690 700 710 720 pF1KA1 THDMEAAHMAATAILNLSTRCREMPQNLSTKPQDLCATRNPDMEVDENGTLDLSMNKQRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 THDMEAAHMAATAILNLSTRCREMPQNLSTKPQDLCATRNPDMEVDENGTLDLSMNKQRP 730 740 750 760 770 780 730 740 750 760 770 780 pF1KA1 RDSCCPILTPLEPMSPQQQAVMNNRCFQLGEGDCWDLPVDYTKMKPRRIDEDESKDITPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDSCCPILTPLEPMSPQQQAVMNNRCFQLGEGDCWDLPVDYTKMKPRRIDEDESKDITPE 790 800 810 820 830 840 790 800 810 820 830 840 pF1KA1 DLDPFQEALEERRYPGEVTIPSPKPKYPQCKESKKDLITLSGCPLADKSIRSMLATSSQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLDPFQEALEERRYPGEVTIPSPKPKYPQCKESKKDLITLSGCPLADKSIRSMLATSSQE 850 860 870 880 890 900 850 860 870 880 890 900 pF1KA1 LKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCDGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCDGQ 910 920 930 940 950 960 910 920 930 940 950 960 pF1KA1 GHITGKYASHRSASGCPLAAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSGSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GHITGKYASHRSASGCPLAAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSGSF 970 980 990 1000 1010 1020 970 980 990 1000 1010 1020 pF1KA1 LTHRSLSGCPRATSAMKKAKLSGEQMLTIKQRASNGIENDEEIKQLDEEIKELNESNSQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTHRSLSGCPRATSAMKKAKLSGEQMLTIKQRASNGIENDEEIKQLDEEIKELNESNSQM 1030 1040 1050 1060 1070 1080 1030 1040 1050 1060 1070 1080 pF1KA1 EADMIKLRTQ--ITTMESNLKTIEEENKVIEQQNESLLHELANLSQSLIHSLANIQLPHM :::::::::: :::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EADMIKLRTQVTITTMESNLKTIEEENKVIEQQNESLLHELANLSQSLIHSLANIQLPHM 1090 1100 1110 1120 1130 1140 1090 1100 1110 1120 1130 pF1KA1 DPINEQNFDAYVTTLTEMYTNQDRYQSPENKALLENIKQAVRGIQV :::::::::::::::::::::::::::::::::::::::::::::: XP_016 DPINEQNFDAYVTTLTEMYTNQDRYQSPENKALLENIKQAVRGIQV 1150 1160 1170 1180 >>NP_001316774 (OMIM: 613084,616521) myelin transcriptio (1186 aa) initn: 5495 init1: 4725 opt: 6971 Z-score: 4511.0 bits: 846.6 E(85289): 0 Smith-Waterman score: 7406; 95.4% identity (95.4% similar) in 1164 aa overlap (23-1132:23-1186) 10 20 30 40 50 60 pF1KA1 MEVDTEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKK :::::::::::::::::::::::::::::::::::::: NP_001 MEVDTEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKK 10 20 30 40 50 60 70 80 90 100 pF1KA1 RKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEE----------- ::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDE 70 80 90 100 110 120 110 120 pF1KA1 -----------------------------------------EEEEEENEDHQMNCHNTRI ::::::::::::::::::: NP_001 DEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRI 130 140 150 160 170 180 130 140 150 160 170 180 pF1KA1 MQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKN 190 200 210 220 230 240 190 200 210 220 230 240 pF1KA1 ENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSENMNDRNYADSMSQQDSRNMNYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSENMNDRNYADSMSQQDSRNMNYV 250 260 270 280 290 300 250 260 270 280 290 300 pF1KA1 MLGKPMNNGLMEKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQERNPQQNMNIRQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLGKPMNNGLMEKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQERNPQQNMNIRQH 310 320 330 340 350 360 310 320 330 340 350 360 pF1KA1 VRPEEDFPGRTPDRNYSDMLNLMRLEEQLSPRSRVFASCAKEDGCHERDDDTTSVNSDRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VRPEEDFPGRTPDRNYSDMLNLMRLEEQLSPRSRVFASCAKEDGCHERDDDTTSVNSDRS 370 380 390 400 410 420 370 380 390 400 410 420 pF1KA1 EEVFDMTKGNLTLLEKAIALETERAKAMREKMAMEAGRRDNMRSYEDQSPRQLPGEDRKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEVFDMTKGNLTLLEKAIALETERAKAMREKMAMEAGRRDNMRSYEDQSPRQLPGEDRKP 430 440 450 460 470 480 430 440 450 460 470 480 pF1KA1 KSSDSHVKKPYY--DPSRTEKKESKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRVPPEI :::::::::::: :::::::::::::::::::::::::::::::::::::::::::::: NP_001 KSSDSHVKKPYYGKDPSRTEKKESKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRVPPEI 490 500 510 520 530 540 490 500 510 520 530 540 pF1KA1 LAMHESVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSSQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAMHESVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSSQA 550 560 570 580 590 600 550 560 570 580 590 600 pF1KA1 SDRVLRPMCFVKQLEIPQYGYRNNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SDRVLRPMCFVKQLEIPQYGYRNNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRA 610 620 630 640 650 660 610 620 630 640 650 660 pF1KA1 IAPKVQTRDISPKGYDDAKRYCKDPSPSSSSTSSYAPSSSSNLSCGGGSSASSTCSKSSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IAPKVQTRDISPKGYDDAKRYCKDPSPSSSSTSSYAPSSSSNLSCGGGSSASSTCSKSSF 670 680 690 700 710 720 670 680 690 700 710 720 pF1KA1 DYTHDMEAAHMAATAILNLSTRCREMPQNLSTKPQDLCATRNPDMEVDENGTLDLSMNKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DYTHDMEAAHMAATAILNLSTRCREMPQNLSTKPQDLCATRNPDMEVDENGTLDLSMNKQ 730 740 750 760 770 780 730 740 750 760 770 780 pF1KA1 RPRDSCCPILTPLEPMSPQQQAVMNNRCFQLGEGDCWDLPVDYTKMKPRRIDEDESKDIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RPRDSCCPILTPLEPMSPQQQAVMNNRCFQLGEGDCWDLPVDYTKMKPRRIDEDESKDIT 790 800 810 820 830 840 790 800 810 820 830 840 pF1KA1 PEDLDPFQEALEERRYPGEVTIPSPKPKYPQCKESKKDLITLSGCPLADKSIRSMLATSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PEDLDPFQEALEERRYPGEVTIPSPKPKYPQCKESKKDLITLSGCPLADKSIRSMLATSS 850 860 870 880 890 900 850 860 870 880 890 900 pF1KA1 QELKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QELKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCD 910 920 930 940 950 960 910 920 930 940 950 960 pF1KA1 GQGHITGKYASHRSASGCPLAAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GQGHITGKYASHRSASGCPLAAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSG 970 980 990 1000 1010 1020 970 980 990 1000 1010 1020 pF1KA1 SFLTHRSLSGCPRATSAMKKAKLSGEQMLTIKQRASNGIENDEEIKQLDEEIKELNESNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SFLTHRSLSGCPRATSAMKKAKLSGEQMLTIKQRASNGIENDEEIKQLDEEIKELNESNS 1030 1040 1050 1060 1070 1080 1030 1040 1050 1060 1070 1080 pF1KA1 QMEADMIKLRTQITTMESNLKTIEEENKVIEQQNESLLHELANLSQSLIHSLANIQLPHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QMEADMIKLRTQITTMESNLKTIEEENKVIEQQNESLLHELANLSQSLIHSLANIQLPHM 1090 1100 1110 1120 1130 1140 1090 1100 1110 1120 1130 pF1KA1 DPINEQNFDAYVTTLTEMYTNQDRYQSPENKALLENIKQAVRGIQV :::::::::::::::::::::::::::::::::::::::::::::: NP_001 DPINEQNFDAYVTTLTEMYTNQDRYQSPENKALLENIKQAVRGIQV 1150 1160 1170 1180 >>NP_001289981 (OMIM: 613084,616521) myelin transcriptio (1186 aa) initn: 5495 init1: 4725 opt: 6971 Z-score: 4511.0 bits: 846.6 E(85289): 0 Smith-Waterman score: 7406; 95.4% identity (95.4% similar) in 1164 aa overlap (23-1132:23-1186) 10 20 30 40 50 60 pF1KA1 MEVDTEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKK :::::::::::::::::::::::::::::::::::::: NP_001 MEVDTEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKK 10 20 30 40 50 60 70 80 90 100 pF1KA1 RKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEE----------- ::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDE 70 80 90 100 110 120 110 120 pF1KA1 -----------------------------------------EEEEEENEDHQMNCHNTRI ::::::::::::::::::: NP_001 DEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRI 130 140 150 160 170 180 130 140 150 160 170 180 pF1KA1 MQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKN 190 200 210 220 230 240 190 200 210 220 230 240 pF1KA1 ENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSENMNDRNYADSMSQQDSRNMNYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSENMNDRNYADSMSQQDSRNMNYV 250 260 270 280 290 300 250 260 270 280 290 300 pF1KA1 MLGKPMNNGLMEKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQERNPQQNMNIRQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLGKPMNNGLMEKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQERNPQQNMNIRQH 310 320 330 340 350 360 310 320 330 340 350 360 pF1KA1 VRPEEDFPGRTPDRNYSDMLNLMRLEEQLSPRSRVFASCAKEDGCHERDDDTTSVNSDRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VRPEEDFPGRTPDRNYSDMLNLMRLEEQLSPRSRVFASCAKEDGCHERDDDTTSVNSDRS 370 380 390 400 410 420 370 380 390 400 410 420 pF1KA1 EEVFDMTKGNLTLLEKAIALETERAKAMREKMAMEAGRRDNMRSYEDQSPRQLPGEDRKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEVFDMTKGNLTLLEKAIALETERAKAMREKMAMEAGRRDNMRSYEDQSPRQLPGEDRKP 430 440 450 460 470 480 430 440 450 460 470 480 pF1KA1 KSSDSHVKKPYY--DPSRTEKKESKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRVPPEI :::::::::::: :::::::::::::::::::::::::::::::::::::::::::::: NP_001 KSSDSHVKKPYYGKDPSRTEKKESKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRVPPEI 490 500 510 520 530 540 490 500 510 520 530 540 pF1KA1 LAMHESVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSSQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAMHESVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSSQA 550 560 570 580 590 600 550 560 570 580 590 600 pF1KA1 SDRVLRPMCFVKQLEIPQYGYRNNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SDRVLRPMCFVKQLEIPQYGYRNNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRA 610 620 630 640 650 660 610 620 630 640 650 660 pF1KA1 IAPKVQTRDISPKGYDDAKRYCKDPSPSSSSTSSYAPSSSSNLSCGGGSSASSTCSKSSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IAPKVQTRDISPKGYDDAKRYCKDPSPSSSSTSSYAPSSSSNLSCGGGSSASSTCSKSSF 670 680 690 700 710 720 670 680 690 700 710 720 pF1KA1 DYTHDMEAAHMAATAILNLSTRCREMPQNLSTKPQDLCATRNPDMEVDENGTLDLSMNKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DYTHDMEAAHMAATAILNLSTRCREMPQNLSTKPQDLCATRNPDMEVDENGTLDLSMNKQ 730 740 750 760 770 780 730 740 750 760 770 780 pF1KA1 RPRDSCCPILTPLEPMSPQQQAVMNNRCFQLGEGDCWDLPVDYTKMKPRRIDEDESKDIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RPRDSCCPILTPLEPMSPQQQAVMNNRCFQLGEGDCWDLPVDYTKMKPRRIDEDESKDIT 790 800 810 820 830 840 790 800 810 820 830 840 pF1KA1 PEDLDPFQEALEERRYPGEVTIPSPKPKYPQCKESKKDLITLSGCPLADKSIRSMLATSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PEDLDPFQEALEERRYPGEVTIPSPKPKYPQCKESKKDLITLSGCPLADKSIRSMLATSS 850 860 870 880 890 900 850 860 870 880 890 900 pF1KA1 QELKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QELKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCD 910 920 930 940 950 960 910 920 930 940 950 960 pF1KA1 GQGHITGKYASHRSASGCPLAAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GQGHITGKYASHRSASGCPLAAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSG 970 980 990 1000 1010 1020 970 980 990 1000 1010 1020 pF1KA1 SFLTHRSLSGCPRATSAMKKAKLSGEQMLTIKQRASNGIENDEEIKQLDEEIKELNESNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SFLTHRSLSGCPRATSAMKKAKLSGEQMLTIKQRASNGIENDEEIKQLDEEIKELNESNS 1030 1040 1050 1060 1070 1080 1030 1040 1050 1060 1070 1080 pF1KA1 QMEADMIKLRTQITTMESNLKTIEEENKVIEQQNESLLHELANLSQSLIHSLANIQLPHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QMEADMIKLRTQITTMESNLKTIEEENKVIEQQNESLLHELANLSQSLIHSLANIQLPHM 1090 1100 1110 1120 1130 1140 1090 1100 1110 1120 1130 pF1KA1 DPINEQNFDAYVTTLTEMYTNQDRYQSPENKALLENIKQAVRGIQV :::::::::::::::::::::::::::::::::::::::::::::: NP_001 DPINEQNFDAYVTTLTEMYTNQDRYQSPENKALLENIKQAVRGIQV 1150 1160 1170 1180 >>XP_011508628 (OMIM: 613084,616521) PREDICTED: myelin t (1188 aa) initn: 6759 init1: 4147 opt: 6957 Z-score: 4502.0 bits: 845.0 E(85289): 0 Smith-Waterman score: 7392; 95.2% identity (95.2% similar) in 1166 aa overlap (23-1132:23-1188) 10 20 30 40 50 60 pF1KA1 MEVDTEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKK :::::::::::::::::::::::::::::::::::::: XP_011 MEVDTEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKK 10 20 30 40 50 60 70 80 90 100 pF1KA1 RKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEE----------- ::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDE 70 80 90 100 110 120 110 120 pF1KA1 -----------------------------------------EEEEEENEDHQMNCHNTRI ::::::::::::::::::: XP_011 DEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRI 130 140 150 160 170 180 130 140 150 160 170 180 pF1KA1 MQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKN 190 200 210 220 230 240 190 200 210 220 230 240 pF1KA1 ENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSENMNDRNYADSMSQQDSRNMNYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSENMNDRNYADSMSQQDSRNMNYV 250 260 270 280 290 300 250 260 270 280 290 300 pF1KA1 MLGKPMNNGLMEKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQERNPQQNMNIRQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MLGKPMNNGLMEKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQERNPQQNMNIRQH 310 320 330 340 350 360 310 320 330 340 350 360 pF1KA1 VRPEEDFPGRTPDRNYSDMLNLMRLEEQLSPRSRVFASCAKEDGCHERDDDTTSVNSDRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VRPEEDFPGRTPDRNYSDMLNLMRLEEQLSPRSRVFASCAKEDGCHERDDDTTSVNSDRS 370 380 390 400 410 420 370 380 390 400 410 420 pF1KA1 EEVFDMTKGNLTLLEKAIALETERAKAMREKMAMEAGRRDNMRSYEDQSPRQLPGEDRKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEVFDMTKGNLTLLEKAIALETERAKAMREKMAMEAGRRDNMRSYEDQSPRQLPGEDRKP 430 440 450 460 470 480 430 440 450 460 470 480 pF1KA1 KSSDSHVKKPYY--DPSRTEKKESKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRVPPEI :::::::::::: :::::::::::::::::::::::::::::::::::::::::::::: XP_011 KSSDSHVKKPYYGKDPSRTEKKESKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRVPPEI 490 500 510 520 530 540 490 500 510 520 530 540 pF1KA1 LAMHESVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSSQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LAMHESVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSSQA 550 560 570 580 590 600 550 560 570 580 590 600 pF1KA1 SDRVLRPMCFVKQLEIPQYGYRNNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SDRVLRPMCFVKQLEIPQYGYRNNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRA 610 620 630 640 650 660 610 620 630 640 650 660 pF1KA1 IAPKVQTRDISPKGYDDAKRYCKDPSPSSSSTSSYAPSSSSNLSCGGGSSASSTCSKSSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IAPKVQTRDISPKGYDDAKRYCKDPSPSSSSTSSYAPSSSSNLSCGGGSSASSTCSKSSF 670 680 690 700 710 720 670 680 690 700 710 720 pF1KA1 DYTHDMEAAHMAATAILNLSTRCREMPQNLSTKPQDLCATRNPDMEVDENGTLDLSMNKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DYTHDMEAAHMAATAILNLSTRCREMPQNLSTKPQDLCATRNPDMEVDENGTLDLSMNKQ 730 740 750 760 770 780 730 740 750 760 770 780 pF1KA1 RPRDSCCPILTPLEPMSPQQQAVMNNRCFQLGEGDCWDLPVDYTKMKPRRIDEDESKDIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RPRDSCCPILTPLEPMSPQQQAVMNNRCFQLGEGDCWDLPVDYTKMKPRRIDEDESKDIT 790 800 810 820 830 840 790 800 810 820 830 840 pF1KA1 PEDLDPFQEALEERRYPGEVTIPSPKPKYPQCKESKKDLITLSGCPLADKSIRSMLATSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PEDLDPFQEALEERRYPGEVTIPSPKPKYPQCKESKKDLITLSGCPLADKSIRSMLATSS 850 860 870 880 890 900 850 860 870 880 890 900 pF1KA1 QELKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QELKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCD 910 920 930 940 950 960 910 920 930 940 950 960 pF1KA1 GQGHITGKYASHRSASGCPLAAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GQGHITGKYASHRSASGCPLAAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSG 970 980 990 1000 1010 1020 970 980 990 1000 1010 1020 pF1KA1 SFLTHRSLSGCPRATSAMKKAKLSGEQMLTIKQRASNGIENDEEIKQLDEEIKELNESNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SFLTHRSLSGCPRATSAMKKAKLSGEQMLTIKQRASNGIENDEEIKQLDEEIKELNESNS 1030 1040 1050 1060 1070 1080 1030 1040 1050 1060 1070 1080 pF1KA1 QMEADMIKLRTQ--ITTMESNLKTIEEENKVIEQQNESLLHELANLSQSLIHSLANIQLP :::::::::::: :::::::::::::::::::::::::::::::::::::::::::::: XP_011 QMEADMIKLRTQVTITTMESNLKTIEEENKVIEQQNESLLHELANLSQSLIHSLANIQLP 1090 1100 1110 1120 1130 1140 1090 1100 1110 1120 1130 pF1KA1 HMDPINEQNFDAYVTTLTEMYTNQDRYQSPENKALLENIKQAVRGIQV :::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HMDPINEQNFDAYVTTLTEMYTNQDRYQSPENKALLENIKQAVRGIQV 1150 1160 1170 1180 >>XP_016859107 (OMIM: 613084,616521) PREDICTED: myelin t (1146 aa) initn: 7812 init1: 6652 opt: 6691 Z-score: 4330.5 bits: 813.2 E(85289): 0 Smith-Waterman score: 7137; 95.3% identity (95.4% similar) in 1119 aa overlap (21-1087:21-1139) 10 20 30 40 50 60 pF1KA1 MEVDTEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKK :::::::::::::::::::::::::::::::::::::::: XP_016 MEVDTEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKK 10 20 30 40 50 60 70 80 90 100 pF1KA1 RKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEE----------- ::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDE 70 80 90 100 110 120 110 120 pF1KA1 -----------------------------------------EEEEEENEDHQMNCHNTRI ::::::::::::::::::: XP_016 DEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRI 130 140 150 160 170 180 130 140 150 160 170 180 pF1KA1 MQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKN 190 200 210 220 230 240 190 200 210 220 230 240 pF1KA1 ENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSENMNDRNYADSMSQQDSRNMNYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSENMNDRNYADSMSQQDSRNMNYV 250 260 270 280 290 300 250 260 270 280 290 300 pF1KA1 MLGKPMNNGLMEKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQERNPQQNMNIRQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLGKPMNNGLMEKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQERNPQQNMNIRQH 310 320 330 340 350 360 310 320 330 340 350 360 pF1KA1 VRPEEDFPGRTPDRNYSDMLNLMRLEEQLSPRSRVFASCAKEDGCHERDDDTTSVNSDRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VRPEEDFPGRTPDRNYSDMLNLMRLEEQLSPRSRVFASCAKEDGCHERDDDTTSVNSDRS 370 380 390 400 410 420 370 380 390 400 410 420 pF1KA1 EEVFDMTKGNLTLLEKAIALETERAKAMREKMAMEAGRRDNMRSYEDQSPRQLPGEDRKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEVFDMTKGNLTLLEKAIALETERAKAMREKMAMEAGRRDNMRSYEDQSPRQLPGEDRKP 430 440 450 460 470 480 430 440 450 460 470 480 pF1KA1 KSSDSHVKKPYYDPSRTEKKESKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRVPPEILA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSSDSHVKKPYYDPSRTEKKESKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRVPPEILA 490 500 510 520 530 540 490 500 510 520 530 540 pF1KA1 MHESVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSSQASD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MHESVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSSQASD 550 560 570 580 590 600 550 560 570 580 590 600 pF1KA1 RVLRPMCFVKQLEIPQYGYRNNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRAIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RVLRPMCFVKQLEIPQYGYRNNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRAIA 610 620 630 640 650 660 610 620 630 640 650 660 pF1KA1 PKVQTRDISPKGYDDAKRYCKDPSPSSSSTSSYAPSSSSNLSCGGGSSASSTCSKSSFDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PKVQTRDISPKGYDDAKRYCKDPSPSSSSTSSYAPSSSSNLSCGGGSSASSTCSKSSFDY 670 680 690 700 710 720 670 680 690 700 710 720 pF1KA1 THDMEAAHMAATAILNLSTRCREMPQNLSTKPQDLCATRNPDMEVDENGTLDLSMNKQRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 THDMEAAHMAATAILNLSTRCREMPQNLSTKPQDLCATRNPDMEVDENGTLDLSMNKQRP 730 740 750 760 770 780 730 740 750 760 770 780 pF1KA1 RDSCCPILTPLEPMSPQQQAVMNNRCFQLGEGDCWDLPVDYTKMKPRRIDEDESKDITPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDSCCPILTPLEPMSPQQQAVMNNRCFQLGEGDCWDLPVDYTKMKPRRIDEDESKDITPE 790 800 810 820 830 840 790 800 810 820 830 840 pF1KA1 DLDPFQEALEERRYPGEVTIPSPKPKYPQCKESKKDLITLSGCPLADKSIRSMLATSSQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLDPFQEALEERRYPGEVTIPSPKPKYPQCKESKKDLITLSGCPLADKSIRSMLATSSQE 850 860 870 880 890 900 850 860 870 880 890 900 pF1KA1 LKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCDGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCDGQ 910 920 930 940 950 960 910 920 930 940 950 960 pF1KA1 GHITGKYASHRSASGCPLAAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSGSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GHITGKYASHRSASGCPLAAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSGSF 970 980 990 1000 1010 1020 970 980 990 1000 1010 1020 pF1KA1 LTHRSLSGCPRATSAMKKAKLSGEQMLTIKQRASNGIENDEEIKQLDEEIKELNESNSQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTHRSLSGCPRATSAMKKAKLSGEQMLTIKQRASNGIENDEEIKQLDEEIKELNESNSQM 1030 1040 1050 1060 1070 1080 1030 1040 1050 1060 1070 1080 pF1KA1 EADMIKLRTQITTMESNLKTIEEENKVIEQQNESLLHELANLSQSLIHSLANIQLPHMDP ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::. XP_016 EADMIKLRTQITTMESNLKTIEEENKVIEQQNESLLHELANLSQSLIHSLANIQLPHMED 1090 1100 1110 1120 1130 1140 1090 1100 1110 1120 1130 pF1KA1 INEQNFDAYVTTLTEMYTNQDRYQSPENKALLENIKQAVRGIQV XP_016 GVWWGQ 1132 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 10:44:09 2016 done: Thu Nov 3 10:44:12 2016 Total Scan time: 15.740 Total Display time: 0.530 Function used was FASTA [36.3.4 Apr, 2011]