FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1109, 3016 aa 1>>>pF1KA1109 3016 - 3016 aa - 3016 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.9443+/-0.000483; mu= 9.9641+/- 0.030 mean_var=187.6616+/-38.183, 0's: 0 Z-trim(115.4): 62 B-trim: 989 in 1/53 Lambda= 0.093624 statistics sampled from 25779 (25841) to 25779 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.621), E-opt: 0.2 (0.303), width: 16 Scan time: 27.670 The best scores are: opt bits E(85289) XP_006714407 (OMIM: 611565) PREDICTED: uncharacter (5004) 19836 2694.0 0 XP_005263344 (OMIM: 611565) PREDICTED: uncharacter (5005) 19836 2694.0 0 NP_056127 (OMIM: 611565) uncharacterized protein K (5005) 19836 2694.0 0 XP_016864186 (OMIM: 611565) PREDICTED: uncharacter (4970) 12608 1717.7 0 XP_016864184 (OMIM: 611565) PREDICTED: uncharacter (4991) 10980 1497.8 0 XP_005263339 (OMIM: 611565) PREDICTED: uncharacter (5026) 10980 1497.8 0 XP_016864187 (OMIM: 611565) PREDICTED: uncharacter (4170) 10017 1367.7 0 XP_011530632 (OMIM: 611565) PREDICTED: uncharacter (4510) 10017 1367.7 0 XP_011530629 (OMIM: 611565) PREDICTED: uncharacter (5043) 10017 1367.8 0 XP_011530628 (OMIM: 611565) PREDICTED: uncharacter (5050) 10017 1367.8 0 XP_011530627 (OMIM: 611565) PREDICTED: uncharacter (5058) 10017 1367.8 0 XP_011530626 (OMIM: 611565) PREDICTED: uncharacter (5072) 10017 1367.8 0 XP_011530624 (OMIM: 611565) PREDICTED: uncharacter (5092) 10017 1367.8 0 XP_011530622 (OMIM: 611565) PREDICTED: uncharacter (5093) 10017 1367.8 0 XP_011530621 (OMIM: 611565) PREDICTED: uncharacter (5093) 10017 1367.8 0 XP_011530623 (OMIM: 611565) PREDICTED: uncharacter (5093) 10017 1367.8 0 XP_011530625 (OMIM: 611565) PREDICTED: uncharacter (5076) 8858 1211.2 0 XP_016864185 (OMIM: 611565) PREDICTED: uncharacter (4974) 6982 957.8 0 XP_016864188 (OMIM: 611565) PREDICTED: uncharacter (2859) 5646 777.2 0 >>XP_006714407 (OMIM: 611565) PREDICTED: uncharacterized (5004 aa) initn: 19836 init1: 19836 opt: 19836 Z-score: 14476.3 bits: 2694.0 E(85289): 0 Smith-Waterman score: 19836; 100.0% identity (100.0% similar) in 3016 aa overlap (1-3016:1989-5004) 10 20 30 pF1KA1 MPPPPDSCSMKLTIKEIWFSFAAPTNVRSH :::::::::::::::::::::::::::::: XP_006 SPSSDLNGNSVSDEQDEGVESDDLKKDLPLMPPPPDSCSMKLTIKEIWFSFAAPTNVRSH 1960 1970 1980 1990 2000 2010 40 50 60 70 80 90 pF1KA1 THAFSRQLNLLSTATPAVGAWLVPIDQLKSSLNKLETEGTLRICAVMGCIMTEALENKSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 THAFSRQLNLLSTATPAVGAWLVPIDQLKSSLNKLETEGTLRICAVMGCIMTEALENKSV 2020 2030 2040 2050 2060 2070 100 110 120 130 140 150 pF1KA1 HFPLRSKYNRLTKVARFLQENPSCLLCNILHHYLHQANYSIIDDATMSDGLPALVTLKKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HFPLRSKYNRLTKVARFLQENPSCLLCNILHHYLHQANYSIIDDATMSDGLPALVTLKKG 2080 2090 2100 2110 2120 2130 160 170 180 190 200 210 pF1KA1 LVALARQWMKFIVVTPAFKGVSLHRPAQPLKPQIAMDHEHEDGLGLDNGGGLQSDTSADG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LVALARQWMKFIVVTPAFKGVSLHRPAQPLKPQIAMDHEHEDGLGLDNGGGLQSDTSADG 2140 2150 2160 2170 2180 2190 220 230 240 250 260 270 pF1KA1 AEFEFDAATVSEHTMLLEGTANRPPPGSSGPVTGAEIMRKLSKTHTHSDSALKIKGIHPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AEFEFDAATVSEHTMLLEGTANRPPPGSSGPVTGAEIMRKLSKTHTHSDSALKIKGIHPY 2200 2210 2220 2230 2240 2250 280 290 300 310 320 330 pF1KA1 HSLSYTSGDTATDSPVHVGRAGMPVKDSPRKESLLSYLTGSFPSLHNLLEGTPQRSSAAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HSLSYTSGDTATDSPVHVGRAGMPVKDSPRKESLLSYLTGSFPSLHNLLEGTPQRSSAAV 2260 2270 2280 2290 2300 2310 340 350 360 370 380 390 pF1KA1 KSSSLTRTGNTVATDMLSEHPLLSEPSSVSFYNWMSNAVGNRGSVLQESPVTKSGHNSLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KSSSLTRTGNTVATDMLSEHPLLSEPSSVSFYNWMSNAVGNRGSVLQESPVTKSGHNSLP 2320 2330 2340 2350 2360 2370 400 410 420 430 440 450 pF1KA1 TGVAPNLPTIPSASDFNTVLSSDQNTLDGTHSQHSTSQDDVAGVEEANQGFPAVQLADAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TGVAPNLPTIPSASDFNTVLSSDQNTLDGTHSQHSTSQDDVAGVEEANQGFPAVQLADAQ 2380 2390 2400 2410 2420 2430 460 470 480 490 500 510 pF1KA1 VVFKPLLSHTGIQSQDTMPFCYRMYFGEHLSFSGTLDCLRADIVDSDTAKERKGKRARRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VVFKPLLSHTGIQSQDTMPFCYRMYFGEHLSFSGTLDCLRADIVDSDTAKERKGKRARRQ 2440 2450 2460 2470 2480 2490 520 530 540 550 560 570 pF1KA1 GHVNLPPLEFKPALMLGTFSISAVVMEKSVCTPQNSTSALSFHDLSKRYYNTFHCNFTIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GHVNLPPLEFKPALMLGTFSISAVVMEKSVCTPQNSTSALSFHDLSKRYYNTFHCNFTIS 2500 2510 2520 2530 2540 2550 580 590 600 610 620 630 pF1KA1 CQSISQHVDMALVRLIHQFSTMIDDIKATQTDIKLSRYTAGSASPTPTFKTRKHRDFRSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CQSISQHVDMALVRLIHQFSTMIDDIKATQTDIKLSRYTAGSASPTPTFKTRKHRDFRSS 2560 2570 2580 2590 2600 2610 640 650 660 670 680 690 pF1KA1 DFSRSSRGSLNGGNRVNNAKNKRTNNENNKKESRNKNSLGRSERRTSKVSRKGSKDVVDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DFSRSSRGSLNGGNRVNNAKNKRTNNENNKKESRNKNSLGRSERRTSKVSRKGSKDVVDH 2620 2630 2640 2650 2660 2670 700 710 720 730 740 750 pF1KA1 MTIHMDDSDSITVSEQSEPSAECWQNMYKLLNFYSLISDPTGILEKSSETFGPAGVRSPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MTIHMDDSDSITVSEQSEPSAECWQNMYKLLNFYSLISDPTGILEKSSETFGPAGVRSPT 2680 2690 2700 2710 2720 2730 760 770 780 790 800 810 pF1KA1 EPTCKVVFENEQDNSSLTKTQRKRSLVTSEPQHVTLIVFGIGMVNRTHLEADIGGLTMES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EPTCKVVFENEQDNSSLTKTQRKRSLVTSEPQHVTLIVFGIGMVNRTHLEADIGGLTMES 2740 2750 2760 2770 2780 2790 820 830 840 850 860 870 pF1KA1 ELKRIHGSFTLKEKMKDVLHQKMTETCATAHIGGVNIVLLEGITPNIQLEDFPTSPTSTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ELKRIHGSFTLKEKMKDVLHQKMTETCATAHIGGVNIVLLEGITPNIQLEDFPTSPTSTA 2800 2810 2820 2830 2840 2850 880 890 900 910 920 930 pF1KA1 KQEFLTVVKCSIAKSQALYSAQRGLKTNNAAVFKVGAISINIPQHPATLHSMMVRSSHQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KQEFLTVVKCSIAKSQALYSAQRGLKTNNAAVFKVGAISINIPQHPATLHSMMVRSSHQL 2860 2870 2880 2890 2900 2910 940 950 960 970 980 990 pF1KA1 SKQISDLIRQPSTAPQPVKEDIATPLPSEKTPTSVNQTPVETNEFPQLPEGLEKKPIVLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SKQISDLIRQPSTAPQPVKEDIATPLPSEKTPTSVNQTPVETNEFPQLPEGLEKKPIVLK 2920 2930 2940 2950 2960 2970 1000 1010 1020 1030 1040 1050 pF1KA1 FSAMLDGIAIGAALLPSLKAEYKMGRMRSHGMTGAQTRFTFELPNHRLRFTSKVSATDMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FSAMLDGIAIGAALLPSLKAEYKMGRMRSHGMTGAQTRFTFELPNHRLRFTSKVSATDMS 2980 2990 3000 3010 3020 3030 1060 1070 1080 1090 1100 1110 pF1KA1 TIPPSASLNLPPVTMSGKYIMEEHDSYSDQVWSIDELPSKQGYYLQGNYLRCVAEVGSFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TIPPSASLNLPPVTMSGKYIMEEHDSYSDQVWSIDELPSKQGYYLQGNYLRCVAEVGSFE 3040 3050 3060 3070 3080 3090 1120 1130 1140 1150 1160 1170 pF1KA1 HNLTTDLLNHLVFVQKVFMKEVNEVIQKVSGGEQPIPLWNEHDGTADGDKPKILLYSLNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HNLTTDLLNHLVFVQKVFMKEVNEVIQKVSGGEQPIPLWNEHDGTADGDKPKILLYSLNL 3100 3110 3120 3130 3140 3150 1180 1190 1200 1210 1220 1230 pF1KA1 QFKGIQVTATTPSMRAVRFETGLIELELSNRLQTKASPGSSSYLKLFGKCQVDLNLALGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QFKGIQVTATTPSMRAVRFETGLIELELSNRLQTKASPGSSSYLKLFGKCQVDLNLALGQ 3160 3170 3180 3190 3200 3210 1240 1250 1260 1270 1280 1290 pF1KA1 IVKHQVYEEAGSDFHQVAYFKTRIGLRNALREEISGSSDREAVLITLNRPIVYAQPVAFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IVKHQVYEEAGSDFHQVAYFKTRIGLRNALREEISGSSDREAVLITLNRPIVYAQPVAFD 3220 3230 3240 3250 3260 3270 1300 1310 1320 1330 1340 1350 pF1KA1 RAVLFWLNYKAAYDNWNEQRMALHKDIHMATKEVVDMLPGIQQTSAQAFGTLFLQLTVND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RAVLFWLNYKAAYDNWNEQRMALHKDIHMATKEVVDMLPGIQQTSAQAFGTLFLQLTVND 3280 3290 3300 3310 3320 3330 1360 1370 1380 1390 1400 1410 pF1KA1 LGICLPITNTAQSNHTGDLDTGSALVLTIESTLITACSSESLVSKGHFKNFCIRFADGFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LGICLPITNTAQSNHTGDLDTGSALVLTIESTLITACSSESLVSKGHFKNFCIRFADGFE 3340 3350 3360 3370 3380 3390 1420 1430 1440 1450 1460 1470 pF1KA1 TSWDDWKPEIHGDLVMNACVVPDGTYEVCSRTTGQAAAESSSAGTWTLNVLWKMCGIDVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TSWDDWKPEIHGDLVMNACVVPDGTYEVCSRTTGQAAAESSSAGTWTLNVLWKMCGIDVH 3400 3410 3420 3430 3440 3450 1480 1490 1500 1510 1520 1530 pF1KA1 MDPNIGKRLNALGNTLTTLTGEEDIDDIADLNSVNIADLSDEDEVDTMSPTIHTEATDYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MDPNIGKRLNALGNTLTTLTGEEDIDDIADLNSVNIADLSDEDEVDTMSPTIHTEATDYR 3460 3470 3480 3490 3500 3510 1540 1550 1560 1570 1580 1590 pF1KA1 RQAASASQPGELRGRKIMKRIVDIRELNEQAKVIDDLKKLGASEGTINQEIQRYQQLESV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RQAASASQPGELRGRKIMKRIVDIRELNEQAKVIDDLKKLGASEGTINQEIQRYQQLESV 3520 3530 3540 3550 3560 3570 1600 1610 1620 1630 1640 1650 pF1KA1 AVNDIRRDVRKKLRRSSMRAASLKDKWGLSYKPSYSRSKSISASGRPPLKRMERASSRVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AVNDIRRDVRKKLRRSSMRAASLKDKWGLSYKPSYSRSKSISASGRPPLKRMERASSRVG 3580 3590 3600 3610 3620 3630 1660 1670 1680 1690 1700 1710 pF1KA1 ETEELPEIRVDAASPGPRVTFNIQDTFPEETELDLLSVTIEGPSHYSSNSEGSCSVFSSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ETEELPEIRVDAASPGPRVTFNIQDTFPEETELDLLSVTIEGPSHYSSNSEGSCSVFSSP 3640 3650 3660 3670 3680 3690 1720 1730 1740 1750 1760 1770 pF1KA1 KTPGGFSPGIPFQTEEGRRDDSLSSTSEDSEKDEKDEDHERERFYIYRKPSHTSRKKATG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KTPGGFSPGIPFQTEEGRRDDSLSSTSEDSEKDEKDEDHERERFYIYRKPSHTSRKKATG 3700 3710 3720 3730 3740 3750 1780 1790 1800 1810 1820 1830 pF1KA1 FAAVHQLFTERWPTTPVNRSLSGTATERNIDFELDIRVEIDSGKCVLHPTTLLQEHDDIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FAAVHQLFTERWPTTPVNRSLSGTATERNIDFELDIRVEIDSGKCVLHPTTLLQEHDDIS 3760 3770 3780 3790 3800 3810 1840 1850 1860 1870 1880 1890 pF1KA1 LRRSYDRSSRSLDQDSPSKKKKFQTNYASTTHLMTGKKVPSSLQTKPSDLETTVFYIPGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LRRSYDRSSRSLDQDSPSKKKKFQTNYASTTHLMTGKKVPSSLQTKPSDLETTVFYIPGV 3820 3830 3840 3850 3860 3870 1900 1910 1920 1930 1940 1950 pF1KA1 DVKLHYNSKTLKTESPNASRGSSLPRTLSKESKLYGMKDSATSPPSPPLPSTVQSKTNTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DVKLHYNSKTLKTESPNASRGSSLPRTLSKESKLYGMKDSATSPPSPPLPSTVQSKTNTL 3880 3890 3900 3910 3920 3930 1960 1970 1980 1990 2000 2010 pF1KA1 LPPQPPPIPAAKGKGSGGVKTAKLYAWVALQSLPEEMVISPCLLDFLEKALETIPITPVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LPPQPPPIPAAKGKGSGGVKTAKLYAWVALQSLPEEMVISPCLLDFLEKALETIPITPVE 3940 3950 3960 3970 3980 3990 2020 2030 2040 2050 2060 2070 pF1KA1 RNYTAVSSQDEDMGHFEIPDPMEESTTSLVSSSTSAYSSFPVDVVVYVRVQPSQIKFSCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RNYTAVSSQDEDMGHFEIPDPMEESTTSLVSSSTSAYSSFPVDVVVYVRVQPSQIKFSCL 4000 4010 4020 4030 4040 4050 2080 2090 2100 2110 2120 2130 pF1KA1 PVSRVECMLKLPSLDLVFSSNRGELETLGTTYPAETLSPGGNATQSGTKTSASKTGIPGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PVSRVECMLKLPSLDLVFSSNRGELETLGTTYPAETLSPGGNATQSGTKTSASKTGIPGS 4060 4070 4080 4090 4100 4110 2140 2150 2160 2170 2180 2190 pF1KA1 SGLGSPLGRSRHSSSQSDLTSSSSSSSGLSFTACMSDFSLYVFHPYGAGKQKTAVSGLTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SGLGSPLGRSRHSSSQSDLTSSSSSSSGLSFTACMSDFSLYVFHPYGAGKQKTAVSGLTP 4120 4130 4140 4150 4160 4170 2200 2210 2220 2230 2240 2250 pF1KA1 GSGGLGNVDEEPTSVTGRKDSLSINLEFVKVSLSRIRRSGGASFFESQSVSKSASKMDTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GSGGLGNVDEEPTSVTGRKDSLSINLEFVKVSLSRIRRSGGASFFESQSVSKSASKMDTT 4180 4190 4200 4210 4220 4230 2260 2270 2280 2290 2300 2310 pF1KA1 LINISAVCDIGSASFKYDMRRLSEILAFPRAWYRRSIARRLFLGDQTINLPTSGPGTPDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LINISAVCDIGSASFKYDMRRLSEILAFPRAWYRRSIARRLFLGDQTINLPTSGPGTPDS 4240 4250 4260 4270 4280 4290 2320 2330 2340 2350 2360 2370 pF1KA1 IEGVSQHLSPESSRKAYCKTWEQPSQSASFTHMPQSPNVFNEHMTNSTMSPGTVGQSLKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IEGVSQHLSPESSRKAYCKTWEQPSQSASFTHMPQSPNVFNEHMTNSTMSPGTVGQSLKS 4300 4310 4320 4330 4340 4350 2380 2390 2400 2410 2420 2430 pF1KA1 PASIRSRSVSDSSVPRRDSLSKTSTPFNKSNKAASQQGTPWETLVVFAINLKQLNVQMNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PASIRSRSVSDSSVPRRDSLSKTSTPFNKSNKAASQQGTPWETLVVFAINLKQLNVQMNM 4360 4370 4380 4390 4400 4410 2440 2450 2460 2470 2480 2490 pF1KA1 SNVMGNTTWTTSGLKSQGRLSVGSNRDREISMSVGLGRSQLDSKGGVVGGTIDVNALEMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SNVMGNTTWTTSGLKSQGRLSVGSNRDREISMSVGLGRSQLDSKGGVVGGTIDVNALEMV 4420 4430 4440 4450 4460 4470 2500 2510 2520 2530 2540 2550 pF1KA1 AHISEHPNQQPSHKIQITMGSTEARVDYMGSSILMGIFSNADLKLQDEWKVNLYNTLDSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AHISEHPNQQPSHKIQITMGSTEARVDYMGSSILMGIFSNADLKLQDEWKVNLYNTLDSS 4480 4490 4500 4510 4520 4530 2560 2570 2580 2590 2600 2610 pF1KA1 ITDKSEIFVHGDLKWDIFQVMISRSTTPDLIKIGMKLQEFFTQQFDTSKRALSTWGPVPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ITDKSEIFVHGDLKWDIFQVMISRSTTPDLIKIGMKLQEFFTQQFDTSKRALSTWGPVPY 4540 4550 4560 4570 4580 4590 2620 2630 2640 2650 2660 2670 pF1KA1 LPPKTMTSNLEKSSQEQLLDAAHHRHWPGVLKVVSGCHISLFQIPLPEDGMQFGGSMSLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LPPKTMTSNLEKSSQEQLLDAAHHRHWPGVLKVVSGCHISLFQIPLPEDGMQFGGSMSLH 4600 4610 4620 4630 4640 4650 2680 2690 2700 2710 2720 2730 pF1KA1 GNHMTLACFHGPNFRSKSWALFHLEEPNIAFWTEAQKIWEDGSSDHSTYIVQTLDFHLGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GNHMTLACFHGPNFRSKSWALFHLEEPNIAFWTEAQKIWEDGSSDHSTYIVQTLDFHLGH 4660 4670 4680 4690 4700 4710 2740 2750 2760 2770 2780 2790 pF1KA1 NTMVTKPCGALESPMATITKITRRRHENPPHGVASVKEWFNYVTATRNEELNLLRNVDAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NTMVTKPCGALESPMATITKITRRRHENPPHGVASVKEWFNYVTATRNEELNLLRNVDAN 4720 4730 4740 4750 4760 4770 2800 2810 2820 2830 2840 2850 pF1KA1 NTENSTTVKNSSLLSGFRGGSSYNHETETIFALPRMQLDFKSIHVQEPQEPSLQDASLKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NTENSTTVKNSSLLSGFRGGSSYNHETETIFALPRMQLDFKSIHVQEPQEPSLQDASLKP 4780 4790 4800 4810 4820 4830 2860 2870 2880 2890 2900 2910 pF1KA1 KVECSVVTEFTDHICVTMDAELIMFLHDLVSAYLKEKEKAIFPPRILSTRPGQKSPIIIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KVECSVVTEFTDHICVTMDAELIMFLHDLVSAYLKEKEKAIFPPRILSTRPGQKSPIIIH 4840 4850 4860 4870 4880 4890 2920 2930 2940 2950 2960 2970 pF1KA1 DDNSSDKDREDSITYTTVDWRDFMCNTWHLEPTLRLISWTGRKIDPVGVDYILQKLGFHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DDNSSDKDREDSITYTTVDWRDFMCNTWHLEPTLRLISWTGRKIDPVGVDYILQKLGFHH 4900 4910 4920 4930 4940 4950 2980 2990 3000 3010 pF1KA1 ARTTIPKWLQRGVMDPLDKVLSVLIKKLGTALQDEKEKKGKDKEEH :::::::::::::::::::::::::::::::::::::::::::::: XP_006 ARTTIPKWLQRGVMDPLDKVLSVLIKKLGTALQDEKEKKGKDKEEH 4960 4970 4980 4990 5000 >>XP_005263344 (OMIM: 611565) PREDICTED: uncharacterized (5005 aa) initn: 19836 init1: 19836 opt: 19836 Z-score: 14476.3 bits: 2694.0 E(85289): 0 Smith-Waterman score: 19836; 100.0% identity (100.0% similar) in 3016 aa overlap (1-3016:1990-5005) 10 20 30 pF1KA1 MPPPPDSCSMKLTIKEIWFSFAAPTNVRSH :::::::::::::::::::::::::::::: XP_005 SPSSDLNGNSVSDEQDEGVESDDLKKDLPLMPPPPDSCSMKLTIKEIWFSFAAPTNVRSH 1960 1970 1980 1990 2000 2010 40 50 60 70 80 90 pF1KA1 THAFSRQLNLLSTATPAVGAWLVPIDQLKSSLNKLETEGTLRICAVMGCIMTEALENKSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 THAFSRQLNLLSTATPAVGAWLVPIDQLKSSLNKLETEGTLRICAVMGCIMTEALENKSV 2020 2030 2040 2050 2060 2070 100 110 120 130 140 150 pF1KA1 HFPLRSKYNRLTKVARFLQENPSCLLCNILHHYLHQANYSIIDDATMSDGLPALVTLKKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HFPLRSKYNRLTKVARFLQENPSCLLCNILHHYLHQANYSIIDDATMSDGLPALVTLKKG 2080 2090 2100 2110 2120 2130 160 170 180 190 200 210 pF1KA1 LVALARQWMKFIVVTPAFKGVSLHRPAQPLKPQIAMDHEHEDGLGLDNGGGLQSDTSADG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LVALARQWMKFIVVTPAFKGVSLHRPAQPLKPQIAMDHEHEDGLGLDNGGGLQSDTSADG 2140 2150 2160 2170 2180 2190 220 230 240 250 260 270 pF1KA1 AEFEFDAATVSEHTMLLEGTANRPPPGSSGPVTGAEIMRKLSKTHTHSDSALKIKGIHPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AEFEFDAATVSEHTMLLEGTANRPPPGSSGPVTGAEIMRKLSKTHTHSDSALKIKGIHPY 2200 2210 2220 2230 2240 2250 280 290 300 310 320 330 pF1KA1 HSLSYTSGDTATDSPVHVGRAGMPVKDSPRKESLLSYLTGSFPSLHNLLEGTPQRSSAAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HSLSYTSGDTATDSPVHVGRAGMPVKDSPRKESLLSYLTGSFPSLHNLLEGTPQRSSAAV 2260 2270 2280 2290 2300 2310 340 350 360 370 380 390 pF1KA1 KSSSLTRTGNTVATDMLSEHPLLSEPSSVSFYNWMSNAVGNRGSVLQESPVTKSGHNSLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KSSSLTRTGNTVATDMLSEHPLLSEPSSVSFYNWMSNAVGNRGSVLQESPVTKSGHNSLP 2320 2330 2340 2350 2360 2370 400 410 420 430 440 450 pF1KA1 TGVAPNLPTIPSASDFNTVLSSDQNTLDGTHSQHSTSQDDVAGVEEANQGFPAVQLADAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TGVAPNLPTIPSASDFNTVLSSDQNTLDGTHSQHSTSQDDVAGVEEANQGFPAVQLADAQ 2380 2390 2400 2410 2420 2430 460 470 480 490 500 510 pF1KA1 VVFKPLLSHTGIQSQDTMPFCYRMYFGEHLSFSGTLDCLRADIVDSDTAKERKGKRARRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VVFKPLLSHTGIQSQDTMPFCYRMYFGEHLSFSGTLDCLRADIVDSDTAKERKGKRARRQ 2440 2450 2460 2470 2480 2490 520 530 540 550 560 570 pF1KA1 GHVNLPPLEFKPALMLGTFSISAVVMEKSVCTPQNSTSALSFHDLSKRYYNTFHCNFTIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GHVNLPPLEFKPALMLGTFSISAVVMEKSVCTPQNSTSALSFHDLSKRYYNTFHCNFTIS 2500 2510 2520 2530 2540 2550 580 590 600 610 620 630 pF1KA1 CQSISQHVDMALVRLIHQFSTMIDDIKATQTDIKLSRYTAGSASPTPTFKTRKHRDFRSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CQSISQHVDMALVRLIHQFSTMIDDIKATQTDIKLSRYTAGSASPTPTFKTRKHRDFRSS 2560 2570 2580 2590 2600 2610 640 650 660 670 680 690 pF1KA1 DFSRSSRGSLNGGNRVNNAKNKRTNNENNKKESRNKNSLGRSERRTSKVSRKGSKDVVDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DFSRSSRGSLNGGNRVNNAKNKRTNNENNKKESRNKNSLGRSERRTSKVSRKGSKDVVDH 2620 2630 2640 2650 2660 2670 700 710 720 730 740 750 pF1KA1 MTIHMDDSDSITVSEQSEPSAECWQNMYKLLNFYSLISDPTGILEKSSETFGPAGVRSPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MTIHMDDSDSITVSEQSEPSAECWQNMYKLLNFYSLISDPTGILEKSSETFGPAGVRSPT 2680 2690 2700 2710 2720 2730 760 770 780 790 800 810 pF1KA1 EPTCKVVFENEQDNSSLTKTQRKRSLVTSEPQHVTLIVFGIGMVNRTHLEADIGGLTMES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EPTCKVVFENEQDNSSLTKTQRKRSLVTSEPQHVTLIVFGIGMVNRTHLEADIGGLTMES 2740 2750 2760 2770 2780 2790 820 830 840 850 860 870 pF1KA1 ELKRIHGSFTLKEKMKDVLHQKMTETCATAHIGGVNIVLLEGITPNIQLEDFPTSPTSTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ELKRIHGSFTLKEKMKDVLHQKMTETCATAHIGGVNIVLLEGITPNIQLEDFPTSPTSTA 2800 2810 2820 2830 2840 2850 880 890 900 910 920 930 pF1KA1 KQEFLTVVKCSIAKSQALYSAQRGLKTNNAAVFKVGAISINIPQHPATLHSMMVRSSHQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KQEFLTVVKCSIAKSQALYSAQRGLKTNNAAVFKVGAISINIPQHPATLHSMMVRSSHQL 2860 2870 2880 2890 2900 2910 940 950 960 970 980 990 pF1KA1 SKQISDLIRQPSTAPQPVKEDIATPLPSEKTPTSVNQTPVETNEFPQLPEGLEKKPIVLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SKQISDLIRQPSTAPQPVKEDIATPLPSEKTPTSVNQTPVETNEFPQLPEGLEKKPIVLK 2920 2930 2940 2950 2960 2970 1000 1010 1020 1030 1040 1050 pF1KA1 FSAMLDGIAIGAALLPSLKAEYKMGRMRSHGMTGAQTRFTFELPNHRLRFTSKVSATDMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FSAMLDGIAIGAALLPSLKAEYKMGRMRSHGMTGAQTRFTFELPNHRLRFTSKVSATDMS 2980 2990 3000 3010 3020 3030 1060 1070 1080 1090 1100 1110 pF1KA1 TIPPSASLNLPPVTMSGKYIMEEHDSYSDQVWSIDELPSKQGYYLQGNYLRCVAEVGSFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TIPPSASLNLPPVTMSGKYIMEEHDSYSDQVWSIDELPSKQGYYLQGNYLRCVAEVGSFE 3040 3050 3060 3070 3080 3090 1120 1130 1140 1150 1160 1170 pF1KA1 HNLTTDLLNHLVFVQKVFMKEVNEVIQKVSGGEQPIPLWNEHDGTADGDKPKILLYSLNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HNLTTDLLNHLVFVQKVFMKEVNEVIQKVSGGEQPIPLWNEHDGTADGDKPKILLYSLNL 3100 3110 3120 3130 3140 3150 1180 1190 1200 1210 1220 1230 pF1KA1 QFKGIQVTATTPSMRAVRFETGLIELELSNRLQTKASPGSSSYLKLFGKCQVDLNLALGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QFKGIQVTATTPSMRAVRFETGLIELELSNRLQTKASPGSSSYLKLFGKCQVDLNLALGQ 3160 3170 3180 3190 3200 3210 1240 1250 1260 1270 1280 1290 pF1KA1 IVKHQVYEEAGSDFHQVAYFKTRIGLRNALREEISGSSDREAVLITLNRPIVYAQPVAFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IVKHQVYEEAGSDFHQVAYFKTRIGLRNALREEISGSSDREAVLITLNRPIVYAQPVAFD 3220 3230 3240 3250 3260 3270 1300 1310 1320 1330 1340 1350 pF1KA1 RAVLFWLNYKAAYDNWNEQRMALHKDIHMATKEVVDMLPGIQQTSAQAFGTLFLQLTVND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RAVLFWLNYKAAYDNWNEQRMALHKDIHMATKEVVDMLPGIQQTSAQAFGTLFLQLTVND 3280 3290 3300 3310 3320 3330 1360 1370 1380 1390 1400 1410 pF1KA1 LGICLPITNTAQSNHTGDLDTGSALVLTIESTLITACSSESLVSKGHFKNFCIRFADGFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LGICLPITNTAQSNHTGDLDTGSALVLTIESTLITACSSESLVSKGHFKNFCIRFADGFE 3340 3350 3360 3370 3380 3390 1420 1430 1440 1450 1460 1470 pF1KA1 TSWDDWKPEIHGDLVMNACVVPDGTYEVCSRTTGQAAAESSSAGTWTLNVLWKMCGIDVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TSWDDWKPEIHGDLVMNACVVPDGTYEVCSRTTGQAAAESSSAGTWTLNVLWKMCGIDVH 3400 3410 3420 3430 3440 3450 1480 1490 1500 1510 1520 1530 pF1KA1 MDPNIGKRLNALGNTLTTLTGEEDIDDIADLNSVNIADLSDEDEVDTMSPTIHTEATDYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MDPNIGKRLNALGNTLTTLTGEEDIDDIADLNSVNIADLSDEDEVDTMSPTIHTEATDYR 3460 3470 3480 3490 3500 3510 1540 1550 1560 1570 1580 1590 pF1KA1 RQAASASQPGELRGRKIMKRIVDIRELNEQAKVIDDLKKLGASEGTINQEIQRYQQLESV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RQAASASQPGELRGRKIMKRIVDIRELNEQAKVIDDLKKLGASEGTINQEIQRYQQLESV 3520 3530 3540 3550 3560 3570 1600 1610 1620 1630 1640 1650 pF1KA1 AVNDIRRDVRKKLRRSSMRAASLKDKWGLSYKPSYSRSKSISASGRPPLKRMERASSRVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AVNDIRRDVRKKLRRSSMRAASLKDKWGLSYKPSYSRSKSISASGRPPLKRMERASSRVG 3580 3590 3600 3610 3620 3630 1660 1670 1680 1690 1700 1710 pF1KA1 ETEELPEIRVDAASPGPRVTFNIQDTFPEETELDLLSVTIEGPSHYSSNSEGSCSVFSSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ETEELPEIRVDAASPGPRVTFNIQDTFPEETELDLLSVTIEGPSHYSSNSEGSCSVFSSP 3640 3650 3660 3670 3680 3690 1720 1730 1740 1750 1760 1770 pF1KA1 KTPGGFSPGIPFQTEEGRRDDSLSSTSEDSEKDEKDEDHERERFYIYRKPSHTSRKKATG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KTPGGFSPGIPFQTEEGRRDDSLSSTSEDSEKDEKDEDHERERFYIYRKPSHTSRKKATG 3700 3710 3720 3730 3740 3750 1780 1790 1800 1810 1820 1830 pF1KA1 FAAVHQLFTERWPTTPVNRSLSGTATERNIDFELDIRVEIDSGKCVLHPTTLLQEHDDIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FAAVHQLFTERWPTTPVNRSLSGTATERNIDFELDIRVEIDSGKCVLHPTTLLQEHDDIS 3760 3770 3780 3790 3800 3810 1840 1850 1860 1870 1880 1890 pF1KA1 LRRSYDRSSRSLDQDSPSKKKKFQTNYASTTHLMTGKKVPSSLQTKPSDLETTVFYIPGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LRRSYDRSSRSLDQDSPSKKKKFQTNYASTTHLMTGKKVPSSLQTKPSDLETTVFYIPGV 3820 3830 3840 3850 3860 3870 1900 1910 1920 1930 1940 1950 pF1KA1 DVKLHYNSKTLKTESPNASRGSSLPRTLSKESKLYGMKDSATSPPSPPLPSTVQSKTNTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DVKLHYNSKTLKTESPNASRGSSLPRTLSKESKLYGMKDSATSPPSPPLPSTVQSKTNTL 3880 3890 3900 3910 3920 3930 1960 1970 1980 1990 2000 2010 pF1KA1 LPPQPPPIPAAKGKGSGGVKTAKLYAWVALQSLPEEMVISPCLLDFLEKALETIPITPVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LPPQPPPIPAAKGKGSGGVKTAKLYAWVALQSLPEEMVISPCLLDFLEKALETIPITPVE 3940 3950 3960 3970 3980 3990 2020 2030 2040 2050 2060 2070 pF1KA1 RNYTAVSSQDEDMGHFEIPDPMEESTTSLVSSSTSAYSSFPVDVVVYVRVQPSQIKFSCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RNYTAVSSQDEDMGHFEIPDPMEESTTSLVSSSTSAYSSFPVDVVVYVRVQPSQIKFSCL 4000 4010 4020 4030 4040 4050 2080 2090 2100 2110 2120 2130 pF1KA1 PVSRVECMLKLPSLDLVFSSNRGELETLGTTYPAETLSPGGNATQSGTKTSASKTGIPGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PVSRVECMLKLPSLDLVFSSNRGELETLGTTYPAETLSPGGNATQSGTKTSASKTGIPGS 4060 4070 4080 4090 4100 4110 2140 2150 2160 2170 2180 2190 pF1KA1 SGLGSPLGRSRHSSSQSDLTSSSSSSSGLSFTACMSDFSLYVFHPYGAGKQKTAVSGLTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SGLGSPLGRSRHSSSQSDLTSSSSSSSGLSFTACMSDFSLYVFHPYGAGKQKTAVSGLTP 4120 4130 4140 4150 4160 4170 2200 2210 2220 2230 2240 2250 pF1KA1 GSGGLGNVDEEPTSVTGRKDSLSINLEFVKVSLSRIRRSGGASFFESQSVSKSASKMDTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GSGGLGNVDEEPTSVTGRKDSLSINLEFVKVSLSRIRRSGGASFFESQSVSKSASKMDTT 4180 4190 4200 4210 4220 4230 2260 2270 2280 2290 2300 2310 pF1KA1 LINISAVCDIGSASFKYDMRRLSEILAFPRAWYRRSIARRLFLGDQTINLPTSGPGTPDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LINISAVCDIGSASFKYDMRRLSEILAFPRAWYRRSIARRLFLGDQTINLPTSGPGTPDS 4240 4250 4260 4270 4280 4290 2320 2330 2340 2350 2360 2370 pF1KA1 IEGVSQHLSPESSRKAYCKTWEQPSQSASFTHMPQSPNVFNEHMTNSTMSPGTVGQSLKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IEGVSQHLSPESSRKAYCKTWEQPSQSASFTHMPQSPNVFNEHMTNSTMSPGTVGQSLKS 4300 4310 4320 4330 4340 4350 2380 2390 2400 2410 2420 2430 pF1KA1 PASIRSRSVSDSSVPRRDSLSKTSTPFNKSNKAASQQGTPWETLVVFAINLKQLNVQMNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PASIRSRSVSDSSVPRRDSLSKTSTPFNKSNKAASQQGTPWETLVVFAINLKQLNVQMNM 4360 4370 4380 4390 4400 4410 2440 2450 2460 2470 2480 2490 pF1KA1 SNVMGNTTWTTSGLKSQGRLSVGSNRDREISMSVGLGRSQLDSKGGVVGGTIDVNALEMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SNVMGNTTWTTSGLKSQGRLSVGSNRDREISMSVGLGRSQLDSKGGVVGGTIDVNALEMV 4420 4430 4440 4450 4460 4470 2500 2510 2520 2530 2540 2550 pF1KA1 AHISEHPNQQPSHKIQITMGSTEARVDYMGSSILMGIFSNADLKLQDEWKVNLYNTLDSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AHISEHPNQQPSHKIQITMGSTEARVDYMGSSILMGIFSNADLKLQDEWKVNLYNTLDSS 4480 4490 4500 4510 4520 4530 2560 2570 2580 2590 2600 2610 pF1KA1 ITDKSEIFVHGDLKWDIFQVMISRSTTPDLIKIGMKLQEFFTQQFDTSKRALSTWGPVPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ITDKSEIFVHGDLKWDIFQVMISRSTTPDLIKIGMKLQEFFTQQFDTSKRALSTWGPVPY 4540 4550 4560 4570 4580 4590 2620 2630 2640 2650 2660 2670 pF1KA1 LPPKTMTSNLEKSSQEQLLDAAHHRHWPGVLKVVSGCHISLFQIPLPEDGMQFGGSMSLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LPPKTMTSNLEKSSQEQLLDAAHHRHWPGVLKVVSGCHISLFQIPLPEDGMQFGGSMSLH 4600 4610 4620 4630 4640 4650 2680 2690 2700 2710 2720 2730 pF1KA1 GNHMTLACFHGPNFRSKSWALFHLEEPNIAFWTEAQKIWEDGSSDHSTYIVQTLDFHLGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GNHMTLACFHGPNFRSKSWALFHLEEPNIAFWTEAQKIWEDGSSDHSTYIVQTLDFHLGH 4660 4670 4680 4690 4700 4710 2740 2750 2760 2770 2780 2790 pF1KA1 NTMVTKPCGALESPMATITKITRRRHENPPHGVASVKEWFNYVTATRNEELNLLRNVDAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NTMVTKPCGALESPMATITKITRRRHENPPHGVASVKEWFNYVTATRNEELNLLRNVDAN 4720 4730 4740 4750 4760 4770 2800 2810 2820 2830 2840 2850 pF1KA1 NTENSTTVKNSSLLSGFRGGSSYNHETETIFALPRMQLDFKSIHVQEPQEPSLQDASLKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NTENSTTVKNSSLLSGFRGGSSYNHETETIFALPRMQLDFKSIHVQEPQEPSLQDASLKP 4780 4790 4800 4810 4820 4830 2860 2870 2880 2890 2900 2910 pF1KA1 KVECSVVTEFTDHICVTMDAELIMFLHDLVSAYLKEKEKAIFPPRILSTRPGQKSPIIIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KVECSVVTEFTDHICVTMDAELIMFLHDLVSAYLKEKEKAIFPPRILSTRPGQKSPIIIH 4840 4850 4860 4870 4880 4890 2920 2930 2940 2950 2960 2970 pF1KA1 DDNSSDKDREDSITYTTVDWRDFMCNTWHLEPTLRLISWTGRKIDPVGVDYILQKLGFHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DDNSSDKDREDSITYTTVDWRDFMCNTWHLEPTLRLISWTGRKIDPVGVDYILQKLGFHH 4900 4910 4920 4930 4940 4950 2980 2990 3000 3010 pF1KA1 ARTTIPKWLQRGVMDPLDKVLSVLIKKLGTALQDEKEKKGKDKEEH :::::::::::::::::::::::::::::::::::::::::::::: XP_005 ARTTIPKWLQRGVMDPLDKVLSVLIKKLGTALQDEKEKKGKDKEEH 4960 4970 4980 4990 5000 >>NP_056127 (OMIM: 611565) uncharacterized protein KIAA1 (5005 aa) initn: 19836 init1: 19836 opt: 19836 Z-score: 14476.3 bits: 2694.0 E(85289): 0 Smith-Waterman score: 19836; 100.0% identity (100.0% similar) in 3016 aa overlap (1-3016:1990-5005) 10 20 30 pF1KA1 MPPPPDSCSMKLTIKEIWFSFAAPTNVRSH :::::::::::::::::::::::::::::: NP_056 SPSSDLNGNSVSDEQDEGVESDDLKKDLPLMPPPPDSCSMKLTIKEIWFSFAAPTNVRSH 1960 1970 1980 1990 2000 2010 40 50 60 70 80 90 pF1KA1 THAFSRQLNLLSTATPAVGAWLVPIDQLKSSLNKLETEGTLRICAVMGCIMTEALENKSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 THAFSRQLNLLSTATPAVGAWLVPIDQLKSSLNKLETEGTLRICAVMGCIMTEALENKSV 2020 2030 2040 2050 2060 2070 100 110 120 130 140 150 pF1KA1 HFPLRSKYNRLTKVARFLQENPSCLLCNILHHYLHQANYSIIDDATMSDGLPALVTLKKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 HFPLRSKYNRLTKVARFLQENPSCLLCNILHHYLHQANYSIIDDATMSDGLPALVTLKKG 2080 2090 2100 2110 2120 2130 160 170 180 190 200 210 pF1KA1 LVALARQWMKFIVVTPAFKGVSLHRPAQPLKPQIAMDHEHEDGLGLDNGGGLQSDTSADG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LVALARQWMKFIVVTPAFKGVSLHRPAQPLKPQIAMDHEHEDGLGLDNGGGLQSDTSADG 2140 2150 2160 2170 2180 2190 220 230 240 250 260 270 pF1KA1 AEFEFDAATVSEHTMLLEGTANRPPPGSSGPVTGAEIMRKLSKTHTHSDSALKIKGIHPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 AEFEFDAATVSEHTMLLEGTANRPPPGSSGPVTGAEIMRKLSKTHTHSDSALKIKGIHPY 2200 2210 2220 2230 2240 2250 280 290 300 310 320 330 pF1KA1 HSLSYTSGDTATDSPVHVGRAGMPVKDSPRKESLLSYLTGSFPSLHNLLEGTPQRSSAAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 HSLSYTSGDTATDSPVHVGRAGMPVKDSPRKESLLSYLTGSFPSLHNLLEGTPQRSSAAV 2260 2270 2280 2290 2300 2310 340 350 360 370 380 390 pF1KA1 KSSSLTRTGNTVATDMLSEHPLLSEPSSVSFYNWMSNAVGNRGSVLQESPVTKSGHNSLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 KSSSLTRTGNTVATDMLSEHPLLSEPSSVSFYNWMSNAVGNRGSVLQESPVTKSGHNSLP 2320 2330 2340 2350 2360 2370 400 410 420 430 440 450 pF1KA1 TGVAPNLPTIPSASDFNTVLSSDQNTLDGTHSQHSTSQDDVAGVEEANQGFPAVQLADAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 TGVAPNLPTIPSASDFNTVLSSDQNTLDGTHSQHSTSQDDVAGVEEANQGFPAVQLADAQ 2380 2390 2400 2410 2420 2430 460 470 480 490 500 510 pF1KA1 VVFKPLLSHTGIQSQDTMPFCYRMYFGEHLSFSGTLDCLRADIVDSDTAKERKGKRARRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 VVFKPLLSHTGIQSQDTMPFCYRMYFGEHLSFSGTLDCLRADIVDSDTAKERKGKRARRQ 2440 2450 2460 2470 2480 2490 520 530 540 550 560 570 pF1KA1 GHVNLPPLEFKPALMLGTFSISAVVMEKSVCTPQNSTSALSFHDLSKRYYNTFHCNFTIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 GHVNLPPLEFKPALMLGTFSISAVVMEKSVCTPQNSTSALSFHDLSKRYYNTFHCNFTIS 2500 2510 2520 2530 2540 2550 580 590 600 610 620 630 pF1KA1 CQSISQHVDMALVRLIHQFSTMIDDIKATQTDIKLSRYTAGSASPTPTFKTRKHRDFRSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 CQSISQHVDMALVRLIHQFSTMIDDIKATQTDIKLSRYTAGSASPTPTFKTRKHRDFRSS 2560 2570 2580 2590 2600 2610 640 650 660 670 680 690 pF1KA1 DFSRSSRGSLNGGNRVNNAKNKRTNNENNKKESRNKNSLGRSERRTSKVSRKGSKDVVDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 DFSRSSRGSLNGGNRVNNAKNKRTNNENNKKESRNKNSLGRSERRTSKVSRKGSKDVVDH 2620 2630 2640 2650 2660 2670 700 710 720 730 740 750 pF1KA1 MTIHMDDSDSITVSEQSEPSAECWQNMYKLLNFYSLISDPTGILEKSSETFGPAGVRSPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 MTIHMDDSDSITVSEQSEPSAECWQNMYKLLNFYSLISDPTGILEKSSETFGPAGVRSPT 2680 2690 2700 2710 2720 2730 760 770 780 790 800 810 pF1KA1 EPTCKVVFENEQDNSSLTKTQRKRSLVTSEPQHVTLIVFGIGMVNRTHLEADIGGLTMES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 EPTCKVVFENEQDNSSLTKTQRKRSLVTSEPQHVTLIVFGIGMVNRTHLEADIGGLTMES 2740 2750 2760 2770 2780 2790 820 830 840 850 860 870 pF1KA1 ELKRIHGSFTLKEKMKDVLHQKMTETCATAHIGGVNIVLLEGITPNIQLEDFPTSPTSTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 ELKRIHGSFTLKEKMKDVLHQKMTETCATAHIGGVNIVLLEGITPNIQLEDFPTSPTSTA 2800 2810 2820 2830 2840 2850 880 890 900 910 920 930 pF1KA1 KQEFLTVVKCSIAKSQALYSAQRGLKTNNAAVFKVGAISINIPQHPATLHSMMVRSSHQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 KQEFLTVVKCSIAKSQALYSAQRGLKTNNAAVFKVGAISINIPQHPATLHSMMVRSSHQL 2860 2870 2880 2890 2900 2910 940 950 960 970 980 990 pF1KA1 SKQISDLIRQPSTAPQPVKEDIATPLPSEKTPTSVNQTPVETNEFPQLPEGLEKKPIVLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 SKQISDLIRQPSTAPQPVKEDIATPLPSEKTPTSVNQTPVETNEFPQLPEGLEKKPIVLK 2920 2930 2940 2950 2960 2970 1000 1010 1020 1030 1040 1050 pF1KA1 FSAMLDGIAIGAALLPSLKAEYKMGRMRSHGMTGAQTRFTFELPNHRLRFTSKVSATDMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 FSAMLDGIAIGAALLPSLKAEYKMGRMRSHGMTGAQTRFTFELPNHRLRFTSKVSATDMS 2980 2990 3000 3010 3020 3030 1060 1070 1080 1090 1100 1110 pF1KA1 TIPPSASLNLPPVTMSGKYIMEEHDSYSDQVWSIDELPSKQGYYLQGNYLRCVAEVGSFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 TIPPSASLNLPPVTMSGKYIMEEHDSYSDQVWSIDELPSKQGYYLQGNYLRCVAEVGSFE 3040 3050 3060 3070 3080 3090 1120 1130 1140 1150 1160 1170 pF1KA1 HNLTTDLLNHLVFVQKVFMKEVNEVIQKVSGGEQPIPLWNEHDGTADGDKPKILLYSLNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 HNLTTDLLNHLVFVQKVFMKEVNEVIQKVSGGEQPIPLWNEHDGTADGDKPKILLYSLNL 3100 3110 3120 3130 3140 3150 1180 1190 1200 1210 1220 1230 pF1KA1 QFKGIQVTATTPSMRAVRFETGLIELELSNRLQTKASPGSSSYLKLFGKCQVDLNLALGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 QFKGIQVTATTPSMRAVRFETGLIELELSNRLQTKASPGSSSYLKLFGKCQVDLNLALGQ 3160 3170 3180 3190 3200 3210 1240 1250 1260 1270 1280 1290 pF1KA1 IVKHQVYEEAGSDFHQVAYFKTRIGLRNALREEISGSSDREAVLITLNRPIVYAQPVAFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 IVKHQVYEEAGSDFHQVAYFKTRIGLRNALREEISGSSDREAVLITLNRPIVYAQPVAFD 3220 3230 3240 3250 3260 3270 1300 1310 1320 1330 1340 1350 pF1KA1 RAVLFWLNYKAAYDNWNEQRMALHKDIHMATKEVVDMLPGIQQTSAQAFGTLFLQLTVND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 RAVLFWLNYKAAYDNWNEQRMALHKDIHMATKEVVDMLPGIQQTSAQAFGTLFLQLTVND 3280 3290 3300 3310 3320 3330 1360 1370 1380 1390 1400 1410 pF1KA1 LGICLPITNTAQSNHTGDLDTGSALVLTIESTLITACSSESLVSKGHFKNFCIRFADGFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LGICLPITNTAQSNHTGDLDTGSALVLTIESTLITACSSESLVSKGHFKNFCIRFADGFE 3340 3350 3360 3370 3380 3390 1420 1430 1440 1450 1460 1470 pF1KA1 TSWDDWKPEIHGDLVMNACVVPDGTYEVCSRTTGQAAAESSSAGTWTLNVLWKMCGIDVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 TSWDDWKPEIHGDLVMNACVVPDGTYEVCSRTTGQAAAESSSAGTWTLNVLWKMCGIDVH 3400 3410 3420 3430 3440 3450 1480 1490 1500 1510 1520 1530 pF1KA1 MDPNIGKRLNALGNTLTTLTGEEDIDDIADLNSVNIADLSDEDEVDTMSPTIHTEATDYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 MDPNIGKRLNALGNTLTTLTGEEDIDDIADLNSVNIADLSDEDEVDTMSPTIHTEATDYR 3460 3470 3480 3490 3500 3510 1540 1550 1560 1570 1580 1590 pF1KA1 RQAASASQPGELRGRKIMKRIVDIRELNEQAKVIDDLKKLGASEGTINQEIQRYQQLESV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 RQAASASQPGELRGRKIMKRIVDIRELNEQAKVIDDLKKLGASEGTINQEIQRYQQLESV 3520 3530 3540 3550 3560 3570 1600 1610 1620 1630 1640 1650 pF1KA1 AVNDIRRDVRKKLRRSSMRAASLKDKWGLSYKPSYSRSKSISASGRPPLKRMERASSRVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 AVNDIRRDVRKKLRRSSMRAASLKDKWGLSYKPSYSRSKSISASGRPPLKRMERASSRVG 3580 3590 3600 3610 3620 3630 1660 1670 1680 1690 1700 1710 pF1KA1 ETEELPEIRVDAASPGPRVTFNIQDTFPEETELDLLSVTIEGPSHYSSNSEGSCSVFSSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 ETEELPEIRVDAASPGPRVTFNIQDTFPEETELDLLSVTIEGPSHYSSNSEGSCSVFSSP 3640 3650 3660 3670 3680 3690 1720 1730 1740 1750 1760 1770 pF1KA1 KTPGGFSPGIPFQTEEGRRDDSLSSTSEDSEKDEKDEDHERERFYIYRKPSHTSRKKATG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 KTPGGFSPGIPFQTEEGRRDDSLSSTSEDSEKDEKDEDHERERFYIYRKPSHTSRKKATG 3700 3710 3720 3730 3740 3750 1780 1790 1800 1810 1820 1830 pF1KA1 FAAVHQLFTERWPTTPVNRSLSGTATERNIDFELDIRVEIDSGKCVLHPTTLLQEHDDIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 FAAVHQLFTERWPTTPVNRSLSGTATERNIDFELDIRVEIDSGKCVLHPTTLLQEHDDIS 3760 3770 3780 3790 3800 3810 1840 1850 1860 1870 1880 1890 pF1KA1 LRRSYDRSSRSLDQDSPSKKKKFQTNYASTTHLMTGKKVPSSLQTKPSDLETTVFYIPGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LRRSYDRSSRSLDQDSPSKKKKFQTNYASTTHLMTGKKVPSSLQTKPSDLETTVFYIPGV 3820 3830 3840 3850 3860 3870 1900 1910 1920 1930 1940 1950 pF1KA1 DVKLHYNSKTLKTESPNASRGSSLPRTLSKESKLYGMKDSATSPPSPPLPSTVQSKTNTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 DVKLHYNSKTLKTESPNASRGSSLPRTLSKESKLYGMKDSATSPPSPPLPSTVQSKTNTL 3880 3890 3900 3910 3920 3930 1960 1970 1980 1990 2000 2010 pF1KA1 LPPQPPPIPAAKGKGSGGVKTAKLYAWVALQSLPEEMVISPCLLDFLEKALETIPITPVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LPPQPPPIPAAKGKGSGGVKTAKLYAWVALQSLPEEMVISPCLLDFLEKALETIPITPVE 3940 3950 3960 3970 3980 3990 2020 2030 2040 2050 2060 2070 pF1KA1 RNYTAVSSQDEDMGHFEIPDPMEESTTSLVSSSTSAYSSFPVDVVVYVRVQPSQIKFSCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 RNYTAVSSQDEDMGHFEIPDPMEESTTSLVSSSTSAYSSFPVDVVVYVRVQPSQIKFSCL 4000 4010 4020 4030 4040 4050 2080 2090 2100 2110 2120 2130 pF1KA1 PVSRVECMLKLPSLDLVFSSNRGELETLGTTYPAETLSPGGNATQSGTKTSASKTGIPGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 PVSRVECMLKLPSLDLVFSSNRGELETLGTTYPAETLSPGGNATQSGTKTSASKTGIPGS 4060 4070 4080 4090 4100 4110 2140 2150 2160 2170 2180 2190 pF1KA1 SGLGSPLGRSRHSSSQSDLTSSSSSSSGLSFTACMSDFSLYVFHPYGAGKQKTAVSGLTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 SGLGSPLGRSRHSSSQSDLTSSSSSSSGLSFTACMSDFSLYVFHPYGAGKQKTAVSGLTP 4120 4130 4140 4150 4160 4170 2200 2210 2220 2230 2240 2250 pF1KA1 GSGGLGNVDEEPTSVTGRKDSLSINLEFVKVSLSRIRRSGGASFFESQSVSKSASKMDTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 GSGGLGNVDEEPTSVTGRKDSLSINLEFVKVSLSRIRRSGGASFFESQSVSKSASKMDTT 4180 4190 4200 4210 4220 4230 2260 2270 2280 2290 2300 2310 pF1KA1 LINISAVCDIGSASFKYDMRRLSEILAFPRAWYRRSIARRLFLGDQTINLPTSGPGTPDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LINISAVCDIGSASFKYDMRRLSEILAFPRAWYRRSIARRLFLGDQTINLPTSGPGTPDS 4240 4250 4260 4270 4280 4290 2320 2330 2340 2350 2360 2370 pF1KA1 IEGVSQHLSPESSRKAYCKTWEQPSQSASFTHMPQSPNVFNEHMTNSTMSPGTVGQSLKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 IEGVSQHLSPESSRKAYCKTWEQPSQSASFTHMPQSPNVFNEHMTNSTMSPGTVGQSLKS 4300 4310 4320 4330 4340 4350 2380 2390 2400 2410 2420 2430 pF1KA1 PASIRSRSVSDSSVPRRDSLSKTSTPFNKSNKAASQQGTPWETLVVFAINLKQLNVQMNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 PASIRSRSVSDSSVPRRDSLSKTSTPFNKSNKAASQQGTPWETLVVFAINLKQLNVQMNM 4360 4370 4380 4390 4400 4410 2440 2450 2460 2470 2480 2490 pF1KA1 SNVMGNTTWTTSGLKSQGRLSVGSNRDREISMSVGLGRSQLDSKGGVVGGTIDVNALEMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 SNVMGNTTWTTSGLKSQGRLSVGSNRDREISMSVGLGRSQLDSKGGVVGGTIDVNALEMV 4420 4430 4440 4450 4460 4470 2500 2510 2520 2530 2540 2550 pF1KA1 AHISEHPNQQPSHKIQITMGSTEARVDYMGSSILMGIFSNADLKLQDEWKVNLYNTLDSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 AHISEHPNQQPSHKIQITMGSTEARVDYMGSSILMGIFSNADLKLQDEWKVNLYNTLDSS 4480 4490 4500 4510 4520 4530 2560 2570 2580 2590 2600 2610 pF1KA1 ITDKSEIFVHGDLKWDIFQVMISRSTTPDLIKIGMKLQEFFTQQFDTSKRALSTWGPVPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 ITDKSEIFVHGDLKWDIFQVMISRSTTPDLIKIGMKLQEFFTQQFDTSKRALSTWGPVPY 4540 4550 4560 4570 4580 4590 2620 2630 2640 2650 2660 2670 pF1KA1 LPPKTMTSNLEKSSQEQLLDAAHHRHWPGVLKVVSGCHISLFQIPLPEDGMQFGGSMSLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LPPKTMTSNLEKSSQEQLLDAAHHRHWPGVLKVVSGCHISLFQIPLPEDGMQFGGSMSLH 4600 4610 4620 4630 4640 4650 2680 2690 2700 2710 2720 2730 pF1KA1 GNHMTLACFHGPNFRSKSWALFHLEEPNIAFWTEAQKIWEDGSSDHSTYIVQTLDFHLGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 GNHMTLACFHGPNFRSKSWALFHLEEPNIAFWTEAQKIWEDGSSDHSTYIVQTLDFHLGH 4660 4670 4680 4690 4700 4710 2740 2750 2760 2770 2780 2790 pF1KA1 NTMVTKPCGALESPMATITKITRRRHENPPHGVASVKEWFNYVTATRNEELNLLRNVDAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 NTMVTKPCGALESPMATITKITRRRHENPPHGVASVKEWFNYVTATRNEELNLLRNVDAN 4720 4730 4740 4750 4760 4770 2800 2810 2820 2830 2840 2850 pF1KA1 NTENSTTVKNSSLLSGFRGGSSYNHETETIFALPRMQLDFKSIHVQEPQEPSLQDASLKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 NTENSTTVKNSSLLSGFRGGSSYNHETETIFALPRMQLDFKSIHVQEPQEPSLQDASLKP 4780 4790 4800 4810 4820 4830 2860 2870 2880 2890 2900 2910 pF1KA1 KVECSVVTEFTDHICVTMDAELIMFLHDLVSAYLKEKEKAIFPPRILSTRPGQKSPIIIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 KVECSVVTEFTDHICVTMDAELIMFLHDLVSAYLKEKEKAIFPPRILSTRPGQKSPIIIH 4840 4850 4860 4870 4880 4890 2920 2930 2940 2950 2960 2970 pF1KA1 DDNSSDKDREDSITYTTVDWRDFMCNTWHLEPTLRLISWTGRKIDPVGVDYILQKLGFHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 DDNSSDKDREDSITYTTVDWRDFMCNTWHLEPTLRLISWTGRKIDPVGVDYILQKLGFHH 4900 4910 4920 4930 4940 4950 2980 2990 3000 3010 pF1KA1 ARTTIPKWLQRGVMDPLDKVLSVLIKKLGTALQDEKEKKGKDKEEH :::::::::::::::::::::::::::::::::::::::::::::: NP_056 ARTTIPKWLQRGVMDPLDKVLSVLIKKLGTALQDEKEKKGKDKEEH 4960 4970 4980 4990 5000 >>XP_016864186 (OMIM: 611565) PREDICTED: uncharacterized (4970 aa) initn: 19576 init1: 12608 opt: 12608 Z-score: 9200.1 bits: 1717.7 E(85289): 0 Smith-Waterman score: 19510; 98.8% identity (98.8% similar) in 3016 aa overlap (1-3016:1990-4970) 10 20 30 pF1KA1 MPPPPDSCSMKLTIKEIWFSFAAPTNVRSH :::::::::::::::::::::::::::::: XP_016 SPSSDLNGNSVSDEQDEGVESDDLKKDLPLMPPPPDSCSMKLTIKEIWFSFAAPTNVRSH 1960 1970 1980 1990 2000 2010 40 50 60 70 80 90 pF1KA1 THAFSRQLNLLSTATPAVGAWLVPIDQLKSSLNKLETEGTLRICAVMGCIMTEALENKSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 THAFSRQLNLLSTATPAVGAWLVPIDQLKSSLNKLETEGTLRICAVMGCIMTEALENKSV 2020 2030 2040 2050 2060 2070 100 110 120 130 140 150 pF1KA1 HFPLRSKYNRLTKVARFLQENPSCLLCNILHHYLHQANYSIIDDATMSDGLPALVTLKKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HFPLRSKYNRLTKVARFLQENPSCLLCNILHHYLHQANYSIIDDATMSDGLPALVTLKKG 2080 2090 2100 2110 2120 2130 160 170 180 190 200 210 pF1KA1 LVALARQWMKFIVVTPAFKGVSLHRPAQPLKPQIAMDHEHEDGLGLDNGGGLQSDTSADG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LVALARQWMKFIVVTPAFKGVSLHRPAQPLKPQIAMDHEHEDGLGLDNGGGLQSDTSADG 2140 2150 2160 2170 2180 2190 220 230 240 250 260 270 pF1KA1 AEFEFDAATVSEHTMLLEGTANRPPPGSSGPVTGAEIMRKLSKTHTHSDSALKIKGIHPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AEFEFDAATVSEHTMLLEGTANRPPPGSSGPVTGAEIMRKLSKTHTHSDSALKIKGIHPY 2200 2210 2220 2230 2240 2250 280 290 300 310 320 330 pF1KA1 HSLSYTSGDTATDSPVHVGRAGMPVKDSPRKESLLSYLTGSFPSLHNLLEGTPQRSSAAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HSLSYTSGDTATDSPVHVGRAGMPVKDSPRKESLLSYLTGSFPSLHNLLEGTPQRSSAAV 2260 2270 2280 2290 2300 2310 340 350 360 370 380 390 pF1KA1 KSSSLTRTGNTVATDMLSEHPLLSEPSSVSFYNWMSNAVGNRGSVLQESPVTKSGHNSLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSSSLTRTGNTVATDMLSEHPLLSEPSSVSFYNWMSNAVGNRGSVLQESPVTKSGHNSLP 2320 2330 2340 2350 2360 2370 400 410 420 430 440 450 pF1KA1 TGVAPNLPTIPSASDFNTVLSSDQNTLDGTHSQHSTSQDDVAGVEEANQGFPAVQLADAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TGVAPNLPTIPSASDFNTVLSSDQNTLDGTHSQHSTSQDDVAGVEEANQGFPAVQLADAQ 2380 2390 2400 2410 2420 2430 460 470 480 490 500 510 pF1KA1 VVFKPLLSHTGIQSQDTMPFCYRMYFGEHLSFSGTLDCLRADIVDSDTAKERKGKRARRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VVFKPLLSHTGIQSQDTMPFCYRMYFGEHLSFSGTLDCLRADIVDSDTAKERKGKRARRQ 2440 2450 2460 2470 2480 2490 520 530 540 550 560 570 pF1KA1 GHVNLPPLEFKPALMLGTFSISAVVMEKSVCTPQNSTSALSFHDLSKRYYNTFHCNFTIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GHVNLPPLEFKPALMLGTFSISAVVMEKSVCTPQNSTSALSFHDLSKRYYNTFHCNFTIS 2500 2510 2520 2530 2540 2550 580 590 600 610 620 630 pF1KA1 CQSISQHVDMALVRLIHQFSTMIDDIKATQTDIKLSRYTAGSASPTPTFKTRKHRDFRSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CQSISQHVDMALVRLIHQFSTMIDDIKATQTDIKLSRYTAGSASPTPTFKTRKHRDFRSS 2560 2570 2580 2590 2600 2610 640 650 660 670 680 690 pF1KA1 DFSRSSRGSLNGGNRVNNAKNKRTNNENNKKESRNKNSLGRSERRTSKVSRKGSKDVVDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DFSRSSRGSLNGGNRVNNAKNKRTNNENNKKESRNKNSLGRSERRTSKVSRKGSKDVVDH 2620 2630 2640 2650 2660 2670 700 710 720 730 740 750 pF1KA1 MTIHMDDSDSITVSEQSEPSAECWQNMYKLLNFYSLISDPTGILEKSSETFGPAGVRSPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MTIHMDDSDSITVSEQSEPSAECWQNMYKLLNFYSLISDPTGILEKSSETFGPAGVRSPT 2680 2690 2700 2710 2720 2730 760 770 780 790 800 810 pF1KA1 EPTCKVVFENEQDNSSLTKTQRKRSLVTSEPQHVTLIVFGIGMVNRTHLEADIGGLTMES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EPTCKVVFENEQDNSSLTKTQRKRSLVTSEPQHVTLIVFGIGMVNRTHLEADIGGLTMES 2740 2750 2760 2770 2780 2790 820 830 840 850 860 870 pF1KA1 ELKRIHGSFTLKEKMKDVLHQKMTETCATAHIGGVNIVLLEGITPNIQLEDFPTSPTSTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELKRIHGSFTLKEKMKDVLHQKMTETCATAHIGGVNIVLLEGITPNIQLEDFPTSPTSTA 2800 2810 2820 2830 2840 2850 880 890 900 910 920 930 pF1KA1 KQEFLTVVKCSIAKSQALYSAQRGLKTNNAAVFKVGAISINIPQHPATLHSMMVRSSHQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KQEFLTVVKCSIAKSQALYSAQRGLKTNNAAVFKVGAISINIPQHPATLHSMMVRSSHQL 2860 2870 2880 2890 2900 2910 940 950 960 970 980 990 pF1KA1 SKQISDLIRQPSTAPQPVKEDIATPLPSEKTPTSVNQTPVETNEFPQLPEGLEKKPIVLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKQISDLIRQPSTAPQPVKEDIATPLPSEKTPTSVNQTPVETNEFPQLPEGLEKKPIVLK 2920 2930 2940 2950 2960 2970 1000 1010 1020 1030 1040 1050 pF1KA1 FSAMLDGIAIGAALLPSLKAEYKMGRMRSHGMTGAQTRFTFELPNHRLRFTSKVSATDMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FSAMLDGIAIGAALLPSLKAEYKMGRMRSHGMTGAQTRFTFELPNHRLRFTSKVSATDMS 2980 2990 3000 3010 3020 3030 1060 1070 1080 1090 1100 1110 pF1KA1 TIPPSASLNLPPVTMSGKYIMEEHDSYSDQVWSIDELPSKQGYYLQGNYLRCVAEVGSFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TIPPSASLNLPPVTMSGKYIMEEHDSYSDQVWSIDELPSKQGYYLQGNYLRCVAEVGSFE 3040 3050 3060 3070 3080 3090 1120 1130 1140 1150 1160 1170 pF1KA1 HNLTTDLLNHLVFVQKVFMKEVNEVIQKVSGGEQPIPLWNEHDGTADGDKPKILLYSLNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HNLTTDLLNHLVFVQKVFMKEVNEVIQKVSGGEQPIPLWNEHDGTADGDKPKILLYSLNL 3100 3110 3120 3130 3140 3150 1180 1190 1200 1210 1220 1230 pF1KA1 QFKGIQVTATTPSMRAVRFETGLIELELSNRLQTKASPGSSSYLKLFGKCQVDLNLALGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QFKGIQVTATTPSMRAVRFETGLIELELSNRLQTKASPGSSSYLKLFGKCQVDLNLALGQ 3160 3170 3180 3190 3200 3210 1240 1250 1260 1270 1280 1290 pF1KA1 IVKHQVYEEAGSDFHQVAYFKTRIGLRNALREEISGSSDREAVLITLNRPIVYAQPVAFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IVKHQVYEEAGSDFHQVAYFKTRIGLRNALREEISGSSDREAVLITLNRPIVYAQPVAFD 3220 3230 3240 3250 3260 3270 1300 1310 1320 1330 1340 1350 pF1KA1 RAVLFWLNYKAAYDNWNEQRMALHKDIHMATKEVVDMLPGIQQTSAQAFGTLFLQLTVND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RAVLFWLNYKAAYDNWNEQRMALHKDIHMATKEVVDMLPGIQQTSAQAFGTLFLQLTVND 3280 3290 3300 3310 3320 3330 1360 1370 1380 1390 1400 1410 pF1KA1 LGICLPITNTAQSNHTGDLDTGSALVLTIESTLITACSSESLVSKGHFKNFCIRFADGFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGICLPITNTAQSNHTGDLDTGSALVLTIESTLITACSSESLVSKGHFKNFCIRFADGFE 3340 3350 3360 3370 3380 3390 1420 1430 1440 1450 1460 1470 pF1KA1 TSWDDWKPEIHGDLVMNACVVPDGTYEVCSRTTGQAAAESSSAGTWTLNVLWKMCGIDVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSWDDWKPEIHGDLVMNACVVPDGTYEVCSRTTGQAAAESSSAGTWTLNVLWKMCGIDVH 3400 3410 3420 3430 3440 3450 1480 1490 1500 1510 1520 1530 pF1KA1 MDPNIGKRLNALGNTLTTLTGEEDIDDIADLNSVNIADLSDEDEVDTMSPTIHTEATDYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDPNIGKRLNALGNTLTTLTGEEDIDDIADLNSVNIADLSDEDEVDTMSPTIHTEATDYR 3460 3470 3480 3490 3500 3510 1540 1550 1560 1570 1580 1590 pF1KA1 RQAASASQPGELRGRKIMKRIVDIRELNEQAKVIDDLKKLGASEGTINQEIQRYQQLESV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RQAASASQPGELRGRKIMKRIVDIRELNEQAKVIDDLKKLGASEGTINQEIQRYQQLESV 3520 3530 3540 3550 3560 3570 1600 1610 1620 1630 1640 1650 pF1KA1 AVNDIRRDVRKKLRRSSMRAASLKDKWGLSYKPSYSRSKSISASGRPPLKRMERASSRVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVNDIRRDVRKKLRRSSMRAASLKDKWGLSYKPSYSRSKSISASGRPPLKRMERASSRVG 3580 3590 3600 3610 3620 3630 1660 1670 1680 1690 1700 1710 pF1KA1 ETEELPEIRVDAASPGPRVTFNIQDTFPEETELDLLSVTIEGPSHYSSNSEGSCSVFSSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETEELPEIRVDAASPGPRVTFNIQDTFPEETELDLLSVTIEGPSHYSSNSEGSCSVFSSP 3640 3650 3660 3670 3680 3690 1720 1730 1740 1750 1760 1770 pF1KA1 KTPGGFSPGIPFQTEEGRRDDSLSSTSEDSEKDEKDEDHERERFYIYRKPSHTSRKKATG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KTPGGFSPGIPFQTEEGRRDDSLSSTSEDSEKDEKDEDHERERFYIYRKPSHTSRKKATG 3700 3710 3720 3730 3740 3750 1780 1790 1800 1810 1820 1830 pF1KA1 FAAVHQLFTERWPTTPVNRSLSGTATERNIDFELDIRVEIDSGKCVLHPTTLLQEHDDIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FAAVHQLFTERWPTTPVNRSLSGTATERNIDFELDIRVEIDSGKCVLHPTTLLQEHDDIS 3760 3770 3780 3790 3800 3810 1840 1850 1860 1870 1880 1890 pF1KA1 LRRSYDRSSRSLDQDSPSKKKKFQTNYASTTHLMTGKKVPSSLQTKPSDLETTVFYIPGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRRSYDRSSRSLDQDSPSKKKKFQTNYASTTHLMTGKKVPSSLQTKPSDLETTVFYIPGV 3820 3830 3840 3850 3860 3870 1900 1910 1920 1930 1940 1950 pF1KA1 DVKLHYNSKTLKTESPNASRGSSLPRTLSKESKLYGMKDSATSPPSPPLPSTVQSKTNTL ::::::::::::::::::::::::::::::::::: XP_016 DVKLHYNSKTLKTESPNASRGSSLPRTLSKESKLY------------------------- 3880 3890 3900 3910 1960 1970 1980 1990 2000 2010 pF1KA1 LPPQPPPIPAAKGKGSGGVKTAKLYAWVALQSLPEEMVISPCLLDFLEKALETIPITPVE :::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ----------AKGKGSGGVKTAKLYAWVALQSLPEEMVISPCLLDFLEKALETIPITPVE 3920 3930 3940 3950 3960 2020 2030 2040 2050 2060 2070 pF1KA1 RNYTAVSSQDEDMGHFEIPDPMEESTTSLVSSSTSAYSSFPVDVVVYVRVQPSQIKFSCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RNYTAVSSQDEDMGHFEIPDPMEESTTSLVSSSTSAYSSFPVDVVVYVRVQPSQIKFSCL 3970 3980 3990 4000 4010 4020 2080 2090 2100 2110 2120 2130 pF1KA1 PVSRVECMLKLPSLDLVFSSNRGELETLGTTYPAETLSPGGNATQSGTKTSASKTGIPGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PVSRVECMLKLPSLDLVFSSNRGELETLGTTYPAETLSPGGNATQSGTKTSASKTGIPGS 4030 4040 4050 4060 4070 4080 2140 2150 2160 2170 2180 2190 pF1KA1 SGLGSPLGRSRHSSSQSDLTSSSSSSSGLSFTACMSDFSLYVFHPYGAGKQKTAVSGLTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGLGSPLGRSRHSSSQSDLTSSSSSSSGLSFTACMSDFSLYVFHPYGAGKQKTAVSGLTP 4090 4100 4110 4120 4130 4140 2200 2210 2220 2230 2240 2250 pF1KA1 GSGGLGNVDEEPTSVTGRKDSLSINLEFVKVSLSRIRRSGGASFFESQSVSKSASKMDTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSGGLGNVDEEPTSVTGRKDSLSINLEFVKVSLSRIRRSGGASFFESQSVSKSASKMDTT 4150 4160 4170 4180 4190 4200 2260 2270 2280 2290 2300 2310 pF1KA1 LINISAVCDIGSASFKYDMRRLSEILAFPRAWYRRSIARRLFLGDQTINLPTSGPGTPDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LINISAVCDIGSASFKYDMRRLSEILAFPRAWYRRSIARRLFLGDQTINLPTSGPGTPDS 4210 4220 4230 4240 4250 4260 2320 2330 2340 2350 2360 2370 pF1KA1 IEGVSQHLSPESSRKAYCKTWEQPSQSASFTHMPQSPNVFNEHMTNSTMSPGTVGQSLKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IEGVSQHLSPESSRKAYCKTWEQPSQSASFTHMPQSPNVFNEHMTNSTMSPGTVGQSLKS 4270 4280 4290 4300 4310 4320 2380 2390 2400 2410 2420 2430 pF1KA1 PASIRSRSVSDSSVPRRDSLSKTSTPFNKSNKAASQQGTPWETLVVFAINLKQLNVQMNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PASIRSRSVSDSSVPRRDSLSKTSTPFNKSNKAASQQGTPWETLVVFAINLKQLNVQMNM 4330 4340 4350 4360 4370 4380 2440 2450 2460 2470 2480 2490 pF1KA1 SNVMGNTTWTTSGLKSQGRLSVGSNRDREISMSVGLGRSQLDSKGGVVGGTIDVNALEMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SNVMGNTTWTTSGLKSQGRLSVGSNRDREISMSVGLGRSQLDSKGGVVGGTIDVNALEMV 4390 4400 4410 4420 4430 4440 2500 2510 2520 2530 2540 2550 pF1KA1 AHISEHPNQQPSHKIQITMGSTEARVDYMGSSILMGIFSNADLKLQDEWKVNLYNTLDSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AHISEHPNQQPSHKIQITMGSTEARVDYMGSSILMGIFSNADLKLQDEWKVNLYNTLDSS 4450 4460 4470 4480 4490 4500 2560 2570 2580 2590 2600 2610 pF1KA1 ITDKSEIFVHGDLKWDIFQVMISRSTTPDLIKIGMKLQEFFTQQFDTSKRALSTWGPVPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ITDKSEIFVHGDLKWDIFQVMISRSTTPDLIKIGMKLQEFFTQQFDTSKRALSTWGPVPY 4510 4520 4530 4540 4550 4560 2620 2630 2640 2650 2660 2670 pF1KA1 LPPKTMTSNLEKSSQEQLLDAAHHRHWPGVLKVVSGCHISLFQIPLPEDGMQFGGSMSLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPPKTMTSNLEKSSQEQLLDAAHHRHWPGVLKVVSGCHISLFQIPLPEDGMQFGGSMSLH 4570 4580 4590 4600 4610 4620 2680 2690 2700 2710 2720 2730 pF1KA1 GNHMTLACFHGPNFRSKSWALFHLEEPNIAFWTEAQKIWEDGSSDHSTYIVQTLDFHLGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GNHMTLACFHGPNFRSKSWALFHLEEPNIAFWTEAQKIWEDGSSDHSTYIVQTLDFHLGH 4630 4640 4650 4660 4670 4680 2740 2750 2760 2770 2780 2790 pF1KA1 NTMVTKPCGALESPMATITKITRRRHENPPHGVASVKEWFNYVTATRNEELNLLRNVDAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NTMVTKPCGALESPMATITKITRRRHENPPHGVASVKEWFNYVTATRNEELNLLRNVDAN 4690 4700 4710 4720 4730 4740 2800 2810 2820 2830 2840 2850 pF1KA1 NTENSTTVKNSSLLSGFRGGSSYNHETETIFALPRMQLDFKSIHVQEPQEPSLQDASLKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NTENSTTVKNSSLLSGFRGGSSYNHETETIFALPRMQLDFKSIHVQEPQEPSLQDASLKP 4750 4760 4770 4780 4790 4800 2860 2870 2880 2890 2900 2910 pF1KA1 KVECSVVTEFTDHICVTMDAELIMFLHDLVSAYLKEKEKAIFPPRILSTRPGQKSPIIIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KVECSVVTEFTDHICVTMDAELIMFLHDLVSAYLKEKEKAIFPPRILSTRPGQKSPIIIH 4810 4820 4830 4840 4850 4860 2920 2930 2940 2950 2960 2970 pF1KA1 DDNSSDKDREDSITYTTVDWRDFMCNTWHLEPTLRLISWTGRKIDPVGVDYILQKLGFHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DDNSSDKDREDSITYTTVDWRDFMCNTWHLEPTLRLISWTGRKIDPVGVDYILQKLGFHH 4870 4880 4890 4900 4910 4920 2980 2990 3000 3010 pF1KA1 ARTTIPKWLQRGVMDPLDKVLSVLIKKLGTALQDEKEKKGKDKEEH :::::::::::::::::::::::::::::::::::::::::::::: XP_016 ARTTIPKWLQRGVMDPLDKVLSVLIKKLGTALQDEKEKKGKDKEEH 4930 4940 4950 4960 4970 >>XP_016864184 (OMIM: 611565) PREDICTED: uncharacterized (4991 aa) initn: 17947 init1: 10979 opt: 10980 Z-score: 8011.6 bits: 1497.8 E(85289): 0 Smith-Waterman score: 19458; 98.2% identity (98.2% similar) in 3037 aa overlap (1-3016:1990-4991) 10 20 30 pF1KA1 MPPPPDSCSMKLTIKEIWFSFAAPTNVRSH :::::::::::::::::::::::::::::: XP_016 SPSSDLNGNSVSDEQDEGVESDDLKKDLPLMPPPPDSCSMKLTIKEIWFSFAAPTNVRSH 1960 1970 1980 1990 2000 2010 40 50 60 70 80 90 pF1KA1 THAFSRQLNLLSTATPAVGAWLVPIDQLKSSLNKLETEGTLRICAVMGCIMTEALENKSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 THAFSRQLNLLSTATPAVGAWLVPIDQLKSSLNKLETEGTLRICAVMGCIMTEALENKSV 2020 2030 2040 2050 2060 2070 100 110 120 130 140 150 pF1KA1 HFPLRSKYNRLTKVARFLQENPSCLLCNILHHYLHQANYSIIDDATMSDGLPALVTLKKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HFPLRSKYNRLTKVARFLQENPSCLLCNILHHYLHQANYSIIDDATMSDGLPALVTLKKG 2080 2090 2100 2110 2120 2130 160 170 180 190 200 210 pF1KA1 LVALARQWMKFIVVTPAFKGVSLHRPAQPLKPQIAMDHEHEDGLGLDNGGGLQSDTSADG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LVALARQWMKFIVVTPAFKGVSLHRPAQPLKPQIAMDHEHEDGLGLDNGGGLQSDTSADG 2140 2150 2160 2170 2180 2190 220 230 240 250 260 270 pF1KA1 AEFEFDAATVSEHTMLLEGTANRPPPGSSGPVTGAEIMRKLSKTHTHSDSALKIKGIHPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AEFEFDAATVSEHTMLLEGTANRPPPGSSGPVTGAEIMRKLSKTHTHSDSALKIKGIHPY 2200 2210 2220 2230 2240 2250 280 290 300 310 320 330 pF1KA1 HSLSYTSGDTATDSPVHVGRAGMPVKDSPRKESLLSYLTGSFPSLHNLLEGTPQRSSAAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HSLSYTSGDTATDSPVHVGRAGMPVKDSPRKESLLSYLTGSFPSLHNLLEGTPQRSSAAV 2260 2270 2280 2290 2300 2310 340 350 360 370 380 390 pF1KA1 KSSSLTRTGNTVATDMLSEHPLLSEPSSVSFYNWMSNAVGNRGSVLQESPVTKSGHNSLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSSSLTRTGNTVATDMLSEHPLLSEPSSVSFYNWMSNAVGNRGSVLQESPVTKSGHNSLP 2320 2330 2340 2350 2360 2370 400 410 420 430 440 450 pF1KA1 TGVAPNLPTIPSASDFNTVLSSDQNTLDGTHSQHSTSQDDVAGVEEANQGFPAVQLADAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TGVAPNLPTIPSASDFNTVLSSDQNTLDGTHSQHSTSQDDVAGVEEANQGFPAVQLADAQ 2380 2390 2400 2410 2420 2430 460 470 480 490 500 510 pF1KA1 VVFKPLLSHTGIQSQDTMPFCYRMYFGEHLSFSGTLDCLRADIVDSDTAKERKGKRARRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VVFKPLLSHTGIQSQDTMPFCYRMYFGEHLSFSGTLDCLRADIVDSDTAKERKGKRARRQ 2440 2450 2460 2470 2480 2490 520 530 540 550 560 570 pF1KA1 GHVNLPPLEFKPALMLGTFSISAVVMEKSVCTPQNSTSALSFHDLSKRYYNTFHCNFTIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GHVNLPPLEFKPALMLGTFSISAVVMEKSVCTPQNSTSALSFHDLSKRYYNTFHCNFTIS 2500 2510 2520 2530 2540 2550 580 590 600 610 620 630 pF1KA1 CQSISQHVDMALVRLIHQFSTMIDDIKATQTDIKLSRYTAGSASPTPTFKTRKHRDFRSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CQSISQHVDMALVRLIHQFSTMIDDIKATQTDIKLSRYTAGSASPTPTFKTRKHRDFRSS 2560 2570 2580 2590 2600 2610 640 650 660 670 680 690 pF1KA1 DFSRSSRGSLNGGNRVNNAKNKRTNNENNKKESRNKNSLGRSERRTSKVSRKGSKDVVDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DFSRSSRGSLNGGNRVNNAKNKRTNNENNKKESRNKNSLGRSERRTSKVSRKGSKDVVDH 2620 2630 2640 2650 2660 2670 700 710 720 730 740 750 pF1KA1 MTIHMDDSDSITVSEQSEPSAECWQNMYKLLNFYSLISDPTGILEKSSETFGPAGVRSPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MTIHMDDSDSITVSEQSEPSAECWQNMYKLLNFYSLISDPTGILEKSSETFGPAGVRSPT 2680 2690 2700 2710 2720 2730 760 770 780 790 800 810 pF1KA1 EPTCKVVFENEQDNSSLTKTQRKRSLVTSEPQHVTLIVFGIGMVNRTHLEADIGGLTMES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EPTCKVVFENEQDNSSLTKTQRKRSLVTSEPQHVTLIVFGIGMVNRTHLEADIGGLTMES 2740 2750 2760 2770 2780 2790 820 830 840 850 860 870 pF1KA1 ELKRIHGSFTLKEKMKDVLHQKMTETCATAHIGGVNIVLLEGITPNIQLEDFPTSPTSTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELKRIHGSFTLKEKMKDVLHQKMTETCATAHIGGVNIVLLEGITPNIQLEDFPTSPTSTA 2800 2810 2820 2830 2840 2850 880 890 900 910 920 930 pF1KA1 KQEFLTVVKCSIAKSQALYSAQRGLKTNNAAVFKVGAISINIPQHPATLHSMMVRSSHQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KQEFLTVVKCSIAKSQALYSAQRGLKTNNAAVFKVGAISINIPQHPATLHSMMVRSSHQL 2860 2870 2880 2890 2900 2910 940 950 960 970 980 990 pF1KA1 SKQISDLIRQPSTAPQPVKEDIATPLPSEKTPTSVNQTPVETNEFPQLPEGLEKKPIVLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKQISDLIRQPSTAPQPVKEDIATPLPSEKTPTSVNQTPVETNEFPQLPEGLEKKPIVLK 2920 2930 2940 2950 2960 2970 1000 1010 1020 1030 1040 1050 pF1KA1 FSAMLDGIAIGAALLPSLKAEYKMGRMRSHGMTGAQTRFTFELPNHRLRFTSKVSATDMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FSAMLDGIAIGAALLPSLKAEYKMGRMRSHGMTGAQTRFTFELPNHRLRFTSKVSATDMS 2980 2990 3000 3010 3020 3030 1060 1070 1080 1090 1100 1110 pF1KA1 TIPPSASLNLPPVTMSGKYIMEEHDSYSDQVWSIDELPSKQGYYLQGNYLRCVAEVGSFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TIPPSASLNLPPVTMSGKYIMEEHDSYSDQVWSIDELPSKQGYYLQGNYLRCVAEVGSFE 3040 3050 3060 3070 3080 3090 1120 1130 1140 1150 1160 1170 pF1KA1 HNLTTDLLNHLVFVQKVFMKEVNEVIQKVSGGEQPIPLWNEHDGTADGDKPKILLYSLNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HNLTTDLLNHLVFVQKVFMKEVNEVIQKVSGGEQPIPLWNEHDGTADGDKPKILLYSLNL 3100 3110 3120 3130 3140 3150 1180 1190 1200 1210 1220 1230 pF1KA1 QFKGIQVTATTPSMRAVRFETGLIELELSNRLQTKASPGSSSYLKLFGKCQVDLNLALGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QFKGIQVTATTPSMRAVRFETGLIELELSNRLQTKASPGSSSYLKLFGKCQVDLNLALGQ 3160 3170 3180 3190 3200 3210 1240 1250 1260 1270 1280 1290 pF1KA1 IVKHQVYEEAGSDFHQVAYFKTRIGLRNALREEISGSSDREAVLITLNRPIVYAQPVAFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IVKHQVYEEAGSDFHQVAYFKTRIGLRNALREEISGSSDREAVLITLNRPIVYAQPVAFD 3220 3230 3240 3250 3260 3270 1300 1310 1320 1330 1340 1350 pF1KA1 RAVLFWLNYKAAYDNWNEQRMALHKDIHMATKEVVDMLPGIQQTSAQAFGTLFLQLTVND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RAVLFWLNYKAAYDNWNEQRMALHKDIHMATKEVVDMLPGIQQTSAQAFGTLFLQLTVND 3280 3290 3300 3310 3320 3330 1360 1370 1380 1390 1400 1410 pF1KA1 LGICLPITNTAQSNHTGDLDTGSALVLTIESTLITACSSESLVSKGHFKNFCIRFADGFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGICLPITNTAQSNHTGDLDTGSALVLTIESTLITACSSESLVSKGHFKNFCIRFADGFE 3340 3350 3360 3370 3380 3390 1420 1430 1440 1450 1460 1470 pF1KA1 TSWDDWKPEIHGDLVMNACVVPDGTYEVCSRTTGQAAAESSSAGTWTLNVLWKMCGIDVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSWDDWKPEIHGDLVMNACVVPDGTYEVCSRTTGQAAAESSSAGTWTLNVLWKMCGIDVH 3400 3410 3420 3430 3440 3450 1480 1490 1500 1510 1520 1530 pF1KA1 MDPNIGKRLNALGNTLTTLTGEEDIDDIADLNSVNIADLSDEDEVDTMSPTIHTEATDYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDPNIGKRLNALGNTLTTLTGEEDIDDIADLNSVNIADLSDEDEVDTMSPTIHTEATDYR 3460 3470 3480 3490 3500 3510 1540 1550 1560 1570 1580 1590 pF1KA1 RQAASASQPGELRGRKIMKRIVDIRELNEQAKVIDDLKKLGASEGTINQEIQRYQQLESV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RQAASASQPGELRGRKIMKRIVDIRELNEQAKVIDDLKKLGASEGTINQEIQRYQQLESV 3520 3530 3540 3550 3560 3570 1600 1610 1620 1630 1640 1650 pF1KA1 AVNDIRRDVRKKLRRSSMRAASLKDKWGLSYKPSYSRSKSISASGRPPLKRMERASSRVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVNDIRRDVRKKLRRSSMRAASLKDKWGLSYKPSYSRSKSISASGRPPLKRMERASSRVG 3580 3590 3600 3610 3620 3630 1660 1670 1680 pF1KA1 ETEELPEIRVDAASPGPRVTFNIQDT---------------------FPEETELDLLSVT :::::::::::::::::::::::::: ::::::::::::: XP_016 ETEELPEIRVDAASPGPRVTFNIQDTLKNTVWGSTPQSSCPGEGYFQFPEETELDLLSVT 3640 3650 3660 3670 3680 3690 1690 1700 1710 1720 1730 1740 pF1KA1 IEGPSHYSSNSEGSCSVFSSPKTPGGFSPGIPFQTEEGRRDDSLSSTSEDSEKDEKDEDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IEGPSHYSSNSEGSCSVFSSPKTPGGFSPGIPFQTEEGRRDDSLSSTSEDSEKDEKDEDH 3700 3710 3720 3730 3740 3750 1750 1760 1770 1780 1790 1800 pF1KA1 ERERFYIYRKPSHTSRKKATGFAAVHQLFTERWPTTPVNRSLSGTATERNIDFELDIRVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ERERFYIYRKPSHTSRKKATGFAAVHQLFTERWPTTPVNRSLSGTATERNIDFELDIRVE 3760 3770 3780 3790 3800 3810 1810 1820 1830 1840 1850 1860 pF1KA1 IDSGKCVLHPTTLLQEHDDISLRRSYDRSSRSLDQDSPSKKKKFQTNYASTTHLMTGKKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IDSGKCVLHPTTLLQEHDDISLRRSYDRSSRSLDQDSPSKKKKFQTNYASTTHLMTGKKV 3820 3830 3840 3850 3860 3870 1870 1880 1890 1900 1910 1920 pF1KA1 PSSLQTKPSDLETTVFYIPGVDVKLHYNSKTLKTESPNASRGSSLPRTLSKESKLYGMKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSSLQTKPSDLETTVFYIPGVDVKLHYNSKTLKTESPNASRGSSLPRTLSKESKLY---- 3880 3890 3900 3910 3920 3930 1930 1940 1950 1960 1970 1980 pF1KA1 SATSPPSPPLPSTVQSKTNTLLPPQPPPIPAAKGKGSGGVKTAKLYAWVALQSLPEEMVI ::::::::::::::::::::::::::::: XP_016 -------------------------------AKGKGSGGVKTAKLYAWVALQSLPEEMVI 3940 3950 3960 1990 2000 2010 2020 2030 2040 pF1KA1 SPCLLDFLEKALETIPITPVERNYTAVSSQDEDMGHFEIPDPMEESTTSLVSSSTSAYSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPCLLDFLEKALETIPITPVERNYTAVSSQDEDMGHFEIPDPMEESTTSLVSSSTSAYSS 3970 3980 3990 4000 4010 4020 2050 2060 2070 2080 2090 2100 pF1KA1 FPVDVVVYVRVQPSQIKFSCLPVSRVECMLKLPSLDLVFSSNRGELETLGTTYPAETLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FPVDVVVYVRVQPSQIKFSCLPVSRVECMLKLPSLDLVFSSNRGELETLGTTYPAETLSP 4030 4040 4050 4060 4070 4080 2110 2120 2130 2140 2150 2160 pF1KA1 GGNATQSGTKTSASKTGIPGSSGLGSPLGRSRHSSSQSDLTSSSSSSSGLSFTACMSDFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GGNATQSGTKTSASKTGIPGSSGLGSPLGRSRHSSSQSDLTSSSSSSSGLSFTACMSDFS 4090 4100 4110 4120 4130 4140 2170 2180 2190 2200 2210 2220 pF1KA1 LYVFHPYGAGKQKTAVSGLTPGSGGLGNVDEEPTSVTGRKDSLSINLEFVKVSLSRIRRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LYVFHPYGAGKQKTAVSGLTPGSGGLGNVDEEPTSVTGRKDSLSINLEFVKVSLSRIRRS 4150 4160 4170 4180 4190 4200 2230 2240 2250 2260 2270 2280 pF1KA1 GGASFFESQSVSKSASKMDTTLINISAVCDIGSASFKYDMRRLSEILAFPRAWYRRSIAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GGASFFESQSVSKSASKMDTTLINISAVCDIGSASFKYDMRRLSEILAFPRAWYRRSIAR 4210 4220 4230 4240 4250 4260 2290 2300 2310 2320 2330 2340 pF1KA1 RLFLGDQTINLPTSGPGTPDSIEGVSQHLSPESSRKAYCKTWEQPSQSASFTHMPQSPNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLFLGDQTINLPTSGPGTPDSIEGVSQHLSPESSRKAYCKTWEQPSQSASFTHMPQSPNV 4270 4280 4290 4300 4310 4320 2350 2360 2370 2380 2390 2400 pF1KA1 FNEHMTNSTMSPGTVGQSLKSPASIRSRSVSDSSVPRRDSLSKTSTPFNKSNKAASQQGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FNEHMTNSTMSPGTVGQSLKSPASIRSRSVSDSSVPRRDSLSKTSTPFNKSNKAASQQGT 4330 4340 4350 4360 4370 4380 2410 2420 2430 2440 2450 2460 pF1KA1 PWETLVVFAINLKQLNVQMNMSNVMGNTTWTTSGLKSQGRLSVGSNRDREISMSVGLGRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PWETLVVFAINLKQLNVQMNMSNVMGNTTWTTSGLKSQGRLSVGSNRDREISMSVGLGRS 4390 4400 4410 4420 4430 4440 2470 2480 2490 2500 2510 2520 pF1KA1 QLDSKGGVVGGTIDVNALEMVAHISEHPNQQPSHKIQITMGSTEARVDYMGSSILMGIFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLDSKGGVVGGTIDVNALEMVAHISEHPNQQPSHKIQITMGSTEARVDYMGSSILMGIFS 4450 4460 4470 4480 4490 4500 2530 2540 2550 2560 2570 2580 pF1KA1 NADLKLQDEWKVNLYNTLDSSITDKSEIFVHGDLKWDIFQVMISRSTTPDLIKIGMKLQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NADLKLQDEWKVNLYNTLDSSITDKSEIFVHGDLKWDIFQVMISRSTTPDLIKIGMKLQE 4510 4520 4530 4540 4550 4560 2590 2600 2610 2620 2630 2640 pF1KA1 FFTQQFDTSKRALSTWGPVPYLPPKTMTSNLEKSSQEQLLDAAHHRHWPGVLKVVSGCHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FFTQQFDTSKRALSTWGPVPYLPPKTMTSNLEKSSQEQLLDAAHHRHWPGVLKVVSGCHI 4570 4580 4590 4600 4610 4620 2650 2660 2670 2680 2690 2700 pF1KA1 SLFQIPLPEDGMQFGGSMSLHGNHMTLACFHGPNFRSKSWALFHLEEPNIAFWTEAQKIW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLFQIPLPEDGMQFGGSMSLHGNHMTLACFHGPNFRSKSWALFHLEEPNIAFWTEAQKIW 4630 4640 4650 4660 4670 4680 2710 2720 2730 2740 2750 2760 pF1KA1 EDGSSDHSTYIVQTLDFHLGHNTMVTKPCGALESPMATITKITRRRHENPPHGVASVKEW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDGSSDHSTYIVQTLDFHLGHNTMVTKPCGALESPMATITKITRRRHENPPHGVASVKEW 4690 4700 4710 4720 4730 4740 2770 2780 2790 2800 2810 2820 pF1KA1 FNYVTATRNEELNLLRNVDANNTENSTTVKNSSLLSGFRGGSSYNHETETIFALPRMQLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FNYVTATRNEELNLLRNVDANNTENSTTVKNSSLLSGFRGGSSYNHETETIFALPRMQLD 4750 4760 4770 4780 4790 4800 2830 2840 2850 2860 2870 2880 pF1KA1 FKSIHVQEPQEPSLQDASLKPKVECSVVTEFTDHICVTMDAELIMFLHDLVSAYLKEKEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FKSIHVQEPQEPSLQDASLKPKVECSVVTEFTDHICVTMDAELIMFLHDLVSAYLKEKEK 4810 4820 4830 4840 4850 4860 2890 2900 2910 2920 2930 2940 pF1KA1 AIFPPRILSTRPGQKSPIIIHDDNSSDKDREDSITYTTVDWRDFMCNTWHLEPTLRLISW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AIFPPRILSTRPGQKSPIIIHDDNSSDKDREDSITYTTVDWRDFMCNTWHLEPTLRLISW 4870 4880 4890 4900 4910 4920 2950 2960 2970 2980 2990 3000 pF1KA1 TGRKIDPVGVDYILQKLGFHHARTTIPKWLQRGVMDPLDKVLSVLIKKLGTALQDEKEKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TGRKIDPVGVDYILQKLGFHHARTTIPKWLQRGVMDPLDKVLSVLIKKLGTALQDEKEKK 4930 4940 4950 4960 4970 4980 3010 pF1KA1 GKDKEEH ::::::: XP_016 GKDKEEH 4990 >>XP_005263339 (OMIM: 611565) PREDICTED: uncharacterized (5026 aa) initn: 10979 init1: 10979 opt: 10980 Z-score: 8011.6 bits: 1497.8 E(85289): 0 Smith-Waterman score: 19784; 99.3% identity (99.3% similar) in 3037 aa overlap (1-3016:1990-5026) 10 20 30 pF1KA1 MPPPPDSCSMKLTIKEIWFSFAAPTNVRSH :::::::::::::::::::::::::::::: XP_005 SPSSDLNGNSVSDEQDEGVESDDLKKDLPLMPPPPDSCSMKLTIKEIWFSFAAPTNVRSH 1960 1970 1980 1990 2000 2010 40 50 60 70 80 90 pF1KA1 THAFSRQLNLLSTATPAVGAWLVPIDQLKSSLNKLETEGTLRICAVMGCIMTEALENKSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 THAFSRQLNLLSTATPAVGAWLVPIDQLKSSLNKLETEGTLRICAVMGCIMTEALENKSV 2020 2030 2040 2050 2060 2070 100 110 120 130 140 150 pF1KA1 HFPLRSKYNRLTKVARFLQENPSCLLCNILHHYLHQANYSIIDDATMSDGLPALVTLKKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HFPLRSKYNRLTKVARFLQENPSCLLCNILHHYLHQANYSIIDDATMSDGLPALVTLKKG 2080 2090 2100 2110 2120 2130 160 170 180 190 200 210 pF1KA1 LVALARQWMKFIVVTPAFKGVSLHRPAQPLKPQIAMDHEHEDGLGLDNGGGLQSDTSADG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LVALARQWMKFIVVTPAFKGVSLHRPAQPLKPQIAMDHEHEDGLGLDNGGGLQSDTSADG 2140 2150 2160 2170 2180 2190 220 230 240 250 260 270 pF1KA1 AEFEFDAATVSEHTMLLEGTANRPPPGSSGPVTGAEIMRKLSKTHTHSDSALKIKGIHPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AEFEFDAATVSEHTMLLEGTANRPPPGSSGPVTGAEIMRKLSKTHTHSDSALKIKGIHPY 2200 2210 2220 2230 2240 2250 280 290 300 310 320 330 pF1KA1 HSLSYTSGDTATDSPVHVGRAGMPVKDSPRKESLLSYLTGSFPSLHNLLEGTPQRSSAAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HSLSYTSGDTATDSPVHVGRAGMPVKDSPRKESLLSYLTGSFPSLHNLLEGTPQRSSAAV 2260 2270 2280 2290 2300 2310 340 350 360 370 380 390 pF1KA1 KSSSLTRTGNTVATDMLSEHPLLSEPSSVSFYNWMSNAVGNRGSVLQESPVTKSGHNSLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KSSSLTRTGNTVATDMLSEHPLLSEPSSVSFYNWMSNAVGNRGSVLQESPVTKSGHNSLP 2320 2330 2340 2350 2360 2370 400 410 420 430 440 450 pF1KA1 TGVAPNLPTIPSASDFNTVLSSDQNTLDGTHSQHSTSQDDVAGVEEANQGFPAVQLADAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TGVAPNLPTIPSASDFNTVLSSDQNTLDGTHSQHSTSQDDVAGVEEANQGFPAVQLADAQ 2380 2390 2400 2410 2420 2430 460 470 480 490 500 510 pF1KA1 VVFKPLLSHTGIQSQDTMPFCYRMYFGEHLSFSGTLDCLRADIVDSDTAKERKGKRARRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VVFKPLLSHTGIQSQDTMPFCYRMYFGEHLSFSGTLDCLRADIVDSDTAKERKGKRARRQ 2440 2450 2460 2470 2480 2490 520 530 540 550 560 570 pF1KA1 GHVNLPPLEFKPALMLGTFSISAVVMEKSVCTPQNSTSALSFHDLSKRYYNTFHCNFTIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GHVNLPPLEFKPALMLGTFSISAVVMEKSVCTPQNSTSALSFHDLSKRYYNTFHCNFTIS 2500 2510 2520 2530 2540 2550 580 590 600 610 620 630 pF1KA1 CQSISQHVDMALVRLIHQFSTMIDDIKATQTDIKLSRYTAGSASPTPTFKTRKHRDFRSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CQSISQHVDMALVRLIHQFSTMIDDIKATQTDIKLSRYTAGSASPTPTFKTRKHRDFRSS 2560 2570 2580 2590 2600 2610 640 650 660 670 680 690 pF1KA1 DFSRSSRGSLNGGNRVNNAKNKRTNNENNKKESRNKNSLGRSERRTSKVSRKGSKDVVDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DFSRSSRGSLNGGNRVNNAKNKRTNNENNKKESRNKNSLGRSERRTSKVSRKGSKDVVDH 2620 2630 2640 2650 2660 2670 700 710 720 730 740 750 pF1KA1 MTIHMDDSDSITVSEQSEPSAECWQNMYKLLNFYSLISDPTGILEKSSETFGPAGVRSPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MTIHMDDSDSITVSEQSEPSAECWQNMYKLLNFYSLISDPTGILEKSSETFGPAGVRSPT 2680 2690 2700 2710 2720 2730 760 770 780 790 800 810 pF1KA1 EPTCKVVFENEQDNSSLTKTQRKRSLVTSEPQHVTLIVFGIGMVNRTHLEADIGGLTMES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EPTCKVVFENEQDNSSLTKTQRKRSLVTSEPQHVTLIVFGIGMVNRTHLEADIGGLTMES 2740 2750 2760 2770 2780 2790 820 830 840 850 860 870 pF1KA1 ELKRIHGSFTLKEKMKDVLHQKMTETCATAHIGGVNIVLLEGITPNIQLEDFPTSPTSTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ELKRIHGSFTLKEKMKDVLHQKMTETCATAHIGGVNIVLLEGITPNIQLEDFPTSPTSTA 2800 2810 2820 2830 2840 2850 880 890 900 910 920 930 pF1KA1 KQEFLTVVKCSIAKSQALYSAQRGLKTNNAAVFKVGAISINIPQHPATLHSMMVRSSHQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KQEFLTVVKCSIAKSQALYSAQRGLKTNNAAVFKVGAISINIPQHPATLHSMMVRSSHQL 2860 2870 2880 2890 2900 2910 940 950 960 970 980 990 pF1KA1 SKQISDLIRQPSTAPQPVKEDIATPLPSEKTPTSVNQTPVETNEFPQLPEGLEKKPIVLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SKQISDLIRQPSTAPQPVKEDIATPLPSEKTPTSVNQTPVETNEFPQLPEGLEKKPIVLK 2920 2930 2940 2950 2960 2970 1000 1010 1020 1030 1040 1050 pF1KA1 FSAMLDGIAIGAALLPSLKAEYKMGRMRSHGMTGAQTRFTFELPNHRLRFTSKVSATDMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FSAMLDGIAIGAALLPSLKAEYKMGRMRSHGMTGAQTRFTFELPNHRLRFTSKVSATDMS 2980 2990 3000 3010 3020 3030 1060 1070 1080 1090 1100 1110 pF1KA1 TIPPSASLNLPPVTMSGKYIMEEHDSYSDQVWSIDELPSKQGYYLQGNYLRCVAEVGSFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TIPPSASLNLPPVTMSGKYIMEEHDSYSDQVWSIDELPSKQGYYLQGNYLRCVAEVGSFE 3040 3050 3060 3070 3080 3090 1120 1130 1140 1150 1160 1170 pF1KA1 HNLTTDLLNHLVFVQKVFMKEVNEVIQKVSGGEQPIPLWNEHDGTADGDKPKILLYSLNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HNLTTDLLNHLVFVQKVFMKEVNEVIQKVSGGEQPIPLWNEHDGTADGDKPKILLYSLNL 3100 3110 3120 3130 3140 3150 1180 1190 1200 1210 1220 1230 pF1KA1 QFKGIQVTATTPSMRAVRFETGLIELELSNRLQTKASPGSSSYLKLFGKCQVDLNLALGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QFKGIQVTATTPSMRAVRFETGLIELELSNRLQTKASPGSSSYLKLFGKCQVDLNLALGQ 3160 3170 3180 3190 3200 3210 1240 1250 1260 1270 1280 1290 pF1KA1 IVKHQVYEEAGSDFHQVAYFKTRIGLRNALREEISGSSDREAVLITLNRPIVYAQPVAFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IVKHQVYEEAGSDFHQVAYFKTRIGLRNALREEISGSSDREAVLITLNRPIVYAQPVAFD 3220 3230 3240 3250 3260 3270 1300 1310 1320 1330 1340 1350 pF1KA1 RAVLFWLNYKAAYDNWNEQRMALHKDIHMATKEVVDMLPGIQQTSAQAFGTLFLQLTVND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RAVLFWLNYKAAYDNWNEQRMALHKDIHMATKEVVDMLPGIQQTSAQAFGTLFLQLTVND 3280 3290 3300 3310 3320 3330 1360 1370 1380 1390 1400 1410 pF1KA1 LGICLPITNTAQSNHTGDLDTGSALVLTIESTLITACSSESLVSKGHFKNFCIRFADGFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LGICLPITNTAQSNHTGDLDTGSALVLTIESTLITACSSESLVSKGHFKNFCIRFADGFE 3340 3350 3360 3370 3380 3390 1420 1430 1440 1450 1460 1470 pF1KA1 TSWDDWKPEIHGDLVMNACVVPDGTYEVCSRTTGQAAAESSSAGTWTLNVLWKMCGIDVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TSWDDWKPEIHGDLVMNACVVPDGTYEVCSRTTGQAAAESSSAGTWTLNVLWKMCGIDVH 3400 3410 3420 3430 3440 3450 1480 1490 1500 1510 1520 1530 pF1KA1 MDPNIGKRLNALGNTLTTLTGEEDIDDIADLNSVNIADLSDEDEVDTMSPTIHTEATDYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MDPNIGKRLNALGNTLTTLTGEEDIDDIADLNSVNIADLSDEDEVDTMSPTIHTEATDYR 3460 3470 3480 3490 3500 3510 1540 1550 1560 1570 1580 1590 pF1KA1 RQAASASQPGELRGRKIMKRIVDIRELNEQAKVIDDLKKLGASEGTINQEIQRYQQLESV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RQAASASQPGELRGRKIMKRIVDIRELNEQAKVIDDLKKLGASEGTINQEIQRYQQLESV 3520 3530 3540 3550 3560 3570 1600 1610 1620 1630 1640 1650 pF1KA1 AVNDIRRDVRKKLRRSSMRAASLKDKWGLSYKPSYSRSKSISASGRPPLKRMERASSRVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AVNDIRRDVRKKLRRSSMRAASLKDKWGLSYKPSYSRSKSISASGRPPLKRMERASSRVG 3580 3590 3600 3610 3620 3630 1660 1670 1680 pF1KA1 ETEELPEIRVDAASPGPRVTFNIQDT---------------------FPEETELDLLSVT :::::::::::::::::::::::::: ::::::::::::: XP_005 ETEELPEIRVDAASPGPRVTFNIQDTLKNTVWGSTPQSSCPGEGYFQFPEETELDLLSVT 3640 3650 3660 3670 3680 3690 1690 1700 1710 1720 1730 1740 pF1KA1 IEGPSHYSSNSEGSCSVFSSPKTPGGFSPGIPFQTEEGRRDDSLSSTSEDSEKDEKDEDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IEGPSHYSSNSEGSCSVFSSPKTPGGFSPGIPFQTEEGRRDDSLSSTSEDSEKDEKDEDH 3700 3710 3720 3730 3740 3750 1750 1760 1770 1780 1790 1800 pF1KA1 ERERFYIYRKPSHTSRKKATGFAAVHQLFTERWPTTPVNRSLSGTATERNIDFELDIRVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ERERFYIYRKPSHTSRKKATGFAAVHQLFTERWPTTPVNRSLSGTATERNIDFELDIRVE 3760 3770 3780 3790 3800 3810 1810 1820 1830 1840 1850 1860 pF1KA1 IDSGKCVLHPTTLLQEHDDISLRRSYDRSSRSLDQDSPSKKKKFQTNYASTTHLMTGKKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IDSGKCVLHPTTLLQEHDDISLRRSYDRSSRSLDQDSPSKKKKFQTNYASTTHLMTGKKV 3820 3830 3840 3850 3860 3870 1870 1880 1890 1900 1910 1920 pF1KA1 PSSLQTKPSDLETTVFYIPGVDVKLHYNSKTLKTESPNASRGSSLPRTLSKESKLYGMKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PSSLQTKPSDLETTVFYIPGVDVKLHYNSKTLKTESPNASRGSSLPRTLSKESKLYGMKD 3880 3890 3900 3910 3920 3930 1930 1940 1950 1960 1970 1980 pF1KA1 SATSPPSPPLPSTVQSKTNTLLPPQPPPIPAAKGKGSGGVKTAKLYAWVALQSLPEEMVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SATSPPSPPLPSTVQSKTNTLLPPQPPPIPAAKGKGSGGVKTAKLYAWVALQSLPEEMVI 3940 3950 3960 3970 3980 3990 1990 2000 2010 2020 2030 2040 pF1KA1 SPCLLDFLEKALETIPITPVERNYTAVSSQDEDMGHFEIPDPMEESTTSLVSSSTSAYSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SPCLLDFLEKALETIPITPVERNYTAVSSQDEDMGHFEIPDPMEESTTSLVSSSTSAYSS 4000 4010 4020 4030 4040 4050 2050 2060 2070 2080 2090 2100 pF1KA1 FPVDVVVYVRVQPSQIKFSCLPVSRVECMLKLPSLDLVFSSNRGELETLGTTYPAETLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FPVDVVVYVRVQPSQIKFSCLPVSRVECMLKLPSLDLVFSSNRGELETLGTTYPAETLSP 4060 4070 4080 4090 4100 4110 2110 2120 2130 2140 2150 2160 pF1KA1 GGNATQSGTKTSASKTGIPGSSGLGSPLGRSRHSSSQSDLTSSSSSSSGLSFTACMSDFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GGNATQSGTKTSASKTGIPGSSGLGSPLGRSRHSSSQSDLTSSSSSSSGLSFTACMSDFS 4120 4130 4140 4150 4160 4170 2170 2180 2190 2200 2210 2220 pF1KA1 LYVFHPYGAGKQKTAVSGLTPGSGGLGNVDEEPTSVTGRKDSLSINLEFVKVSLSRIRRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LYVFHPYGAGKQKTAVSGLTPGSGGLGNVDEEPTSVTGRKDSLSINLEFVKVSLSRIRRS 4180 4190 4200 4210 4220 4230 2230 2240 2250 2260 2270 2280 pF1KA1 GGASFFESQSVSKSASKMDTTLINISAVCDIGSASFKYDMRRLSEILAFPRAWYRRSIAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GGASFFESQSVSKSASKMDTTLINISAVCDIGSASFKYDMRRLSEILAFPRAWYRRSIAR 4240 4250 4260 4270 4280 4290 2290 2300 2310 2320 2330 2340 pF1KA1 RLFLGDQTINLPTSGPGTPDSIEGVSQHLSPESSRKAYCKTWEQPSQSASFTHMPQSPNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RLFLGDQTINLPTSGPGTPDSIEGVSQHLSPESSRKAYCKTWEQPSQSASFTHMPQSPNV 4300 4310 4320 4330 4340 4350 2350 2360 2370 2380 2390 2400 pF1KA1 FNEHMTNSTMSPGTVGQSLKSPASIRSRSVSDSSVPRRDSLSKTSTPFNKSNKAASQQGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FNEHMTNSTMSPGTVGQSLKSPASIRSRSVSDSSVPRRDSLSKTSTPFNKSNKAASQQGT 4360 4370 4380 4390 4400 4410 2410 2420 2430 2440 2450 2460 pF1KA1 PWETLVVFAINLKQLNVQMNMSNVMGNTTWTTSGLKSQGRLSVGSNRDREISMSVGLGRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PWETLVVFAINLKQLNVQMNMSNVMGNTTWTTSGLKSQGRLSVGSNRDREISMSVGLGRS 4420 4430 4440 4450 4460 4470 2470 2480 2490 2500 2510 2520 pF1KA1 QLDSKGGVVGGTIDVNALEMVAHISEHPNQQPSHKIQITMGSTEARVDYMGSSILMGIFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QLDSKGGVVGGTIDVNALEMVAHISEHPNQQPSHKIQITMGSTEARVDYMGSSILMGIFS 4480 4490 4500 4510 4520 4530 2530 2540 2550 2560 2570 2580 pF1KA1 NADLKLQDEWKVNLYNTLDSSITDKSEIFVHGDLKWDIFQVMISRSTTPDLIKIGMKLQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NADLKLQDEWKVNLYNTLDSSITDKSEIFVHGDLKWDIFQVMISRSTTPDLIKIGMKLQE 4540 4550 4560 4570 4580 4590 2590 2600 2610 2620 2630 2640 pF1KA1 FFTQQFDTSKRALSTWGPVPYLPPKTMTSNLEKSSQEQLLDAAHHRHWPGVLKVVSGCHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FFTQQFDTSKRALSTWGPVPYLPPKTMTSNLEKSSQEQLLDAAHHRHWPGVLKVVSGCHI 4600 4610 4620 4630 4640 4650 2650 2660 2670 2680 2690 2700 pF1KA1 SLFQIPLPEDGMQFGGSMSLHGNHMTLACFHGPNFRSKSWALFHLEEPNIAFWTEAQKIW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SLFQIPLPEDGMQFGGSMSLHGNHMTLACFHGPNFRSKSWALFHLEEPNIAFWTEAQKIW 4660 4670 4680 4690 4700 4710 2710 2720 2730 2740 2750 2760 pF1KA1 EDGSSDHSTYIVQTLDFHLGHNTMVTKPCGALESPMATITKITRRRHENPPHGVASVKEW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EDGSSDHSTYIVQTLDFHLGHNTMVTKPCGALESPMATITKITRRRHENPPHGVASVKEW 4720 4730 4740 4750 4760 4770 2770 2780 2790 2800 2810 2820 pF1KA1 FNYVTATRNEELNLLRNVDANNTENSTTVKNSSLLSGFRGGSSYNHETETIFALPRMQLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FNYVTATRNEELNLLRNVDANNTENSTTVKNSSLLSGFRGGSSYNHETETIFALPRMQLD 4780 4790 4800 4810 4820 4830 2830 2840 2850 2860 2870 2880 pF1KA1 FKSIHVQEPQEPSLQDASLKPKVECSVVTEFTDHICVTMDAELIMFLHDLVSAYLKEKEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FKSIHVQEPQEPSLQDASLKPKVECSVVTEFTDHICVTMDAELIMFLHDLVSAYLKEKEK 4840 4850 4860 4870 4880 4890 2890 2900 2910 2920 2930 2940 pF1KA1 AIFPPRILSTRPGQKSPIIIHDDNSSDKDREDSITYTTVDWRDFMCNTWHLEPTLRLISW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AIFPPRILSTRPGQKSPIIIHDDNSSDKDREDSITYTTVDWRDFMCNTWHLEPTLRLISW 4900 4910 4920 4930 4940 4950 2950 2960 2970 2980 2990 3000 pF1KA1 TGRKIDPVGVDYILQKLGFHHARTTIPKWLQRGVMDPLDKVLSVLIKKLGTALQDEKEKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TGRKIDPVGVDYILQKLGFHHARTTIPKWLQRGVMDPLDKVLSVLIKKLGTALQDEKEKK 4960 4970 4980 4990 5000 5010 3010 pF1KA1 GKDKEEH ::::::: XP_005 GKDKEEH 5020 >>XP_016864187 (OMIM: 611565) PREDICTED: uncharacterized (4170 aa) initn: 18857 init1: 10013 opt: 10017 Z-score: 7309.8 bits: 1367.7 E(85289): 0 Smith-Waterman score: 19269; 97.1% identity (97.1% similar) in 3048 aa overlap (1-2960:1067-4114) 10 20 30 pF1KA1 MPPPPDSCSMKLTIKEIWFSFAAPTNVRSH :::::::::::::::::::::::::::::: XP_016 SPSSDLNGNSVSDEQDEGVESDDLKKDLPLMPPPPDSCSMKLTIKEIWFSFAAPTNVRSH 1040 1050 1060 1070 1080 1090 40 50 60 70 80 90 pF1KA1 THAFSRQLNLLSTATPAVGAWLVPIDQLKSSLNKLETEGTLRICAVMGCIMTEALENKSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 THAFSRQLNLLSTATPAVGAWLVPIDQLKSSLNKLETEGTLRICAVMGCIMTEALENKSV 1100 1110 1120 1130 1140 1150 100 110 120 130 140 150 pF1KA1 HFPLRSKYNRLTKVARFLQENPSCLLCNILHHYLHQANYSIIDDATMSDGLPALVTLKKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HFPLRSKYNRLTKVARFLQENPSCLLCNILHHYLHQANYSIIDDATMSDGLPALVTLKKG 1160 1170 1180 1190 1200 1210 160 170 180 190 200 210 pF1KA1 LVALARQWMKFIVVTPAFKGVSLHRPAQPLKPQIAMDHEHEDGLGLDNGGGLQSDTSADG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LVALARQWMKFIVVTPAFKGVSLHRPAQPLKPQIAMDHEHEDGLGLDNGGGLQSDTSADG 1220 1230 1240 1250 1260 1270 220 230 240 250 260 270 pF1KA1 AEFEFDAATVSEHTMLLEGTANRPPPGSSGPVTGAEIMRKLSKTHTHSDSALKIKGIHPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AEFEFDAATVSEHTMLLEGTANRPPPGSSGPVTGAEIMRKLSKTHTHSDSALKIKGIHPY 1280 1290 1300 1310 1320 1330 280 290 300 310 320 330 pF1KA1 HSLSYTSGDTATDSPVHVGRAGMPVKDSPRKESLLSYLTGSFPSLHNLLEGTPQRSSAAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HSLSYTSGDTATDSPVHVGRAGMPVKDSPRKESLLSYLTGSFPSLHNLLEGTPQRSSAAV 1340 1350 1360 1370 1380 1390 340 350 360 370 380 390 pF1KA1 KSSSLTRTGNTVATDMLSEHPLLSEPSSVSFYNWMSNAVGNRGSVLQESPVTKSGHNSLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSSSLTRTGNTVATDMLSEHPLLSEPSSVSFYNWMSNAVGNRGSVLQESPVTKSGHNSLP 1400 1410 1420 1430 1440 1450 400 410 420 430 440 450 pF1KA1 TGVAPNLPTIPSASDFNTVLSSDQNTLDGTHSQHSTSQDDVAGVEEANQGFPAVQLADAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TGVAPNLPTIPSASDFNTVLSSDQNTLDGTHSQHSTSQDDVAGVEEANQGFPAVQLADAQ 1460 1470 1480 1490 1500 1510 460 470 480 490 500 510 pF1KA1 VVFKPLLSHTGIQSQDTMPFCYRMYFGEHLSFSGTLDCLRADIVDSDTAKERKGKRARRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VVFKPLLSHTGIQSQDTMPFCYRMYFGEHLSFSGTLDCLRADIVDSDTAKERKGKRARRQ 1520 1530 1540 1550 1560 1570 520 530 540 550 560 570 pF1KA1 GHVNLPPLEFKPALMLGTFSISAVVMEKSVCTPQNSTSALSFHDLSKRYYNTFHCNFTIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GHVNLPPLEFKPALMLGTFSISAVVMEKSVCTPQNSTSALSFHDLSKRYYNTFHCNFTIS 1580 1590 1600 1610 1620 1630 580 590 600 610 620 630 pF1KA1 CQSISQHVDMALVRLIHQFSTMIDDIKATQTDIKLSRYTAGSASPTPTFKTRKHRDFRSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CQSISQHVDMALVRLIHQFSTMIDDIKATQTDIKLSRYTAGSASPTPTFKTRKHRDFRSS 1640 1650 1660 1670 1680 1690 640 650 660 670 680 690 pF1KA1 DFSRSSRGSLNGGNRVNNAKNKRTNNENNKKESRNKNSLGRSERRTSKVSRKGSKDVVDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DFSRSSRGSLNGGNRVNNAKNKRTNNENNKKESRNKNSLGRSERRTSKVSRKGSKDVVDH 1700 1710 1720 1730 1740 1750 700 710 720 730 740 750 pF1KA1 MTIHMDDSDSITVSEQSEPSAECWQNMYKLLNFYSLISDPTGILEKSSETFGPAGVRSPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MTIHMDDSDSITVSEQSEPSAECWQNMYKLLNFYSLISDPTGILEKSSETFGPAGVRSPT 1760 1770 1780 1790 1800 1810 760 770 780 790 800 810 pF1KA1 EPTCKVVFENEQDNSSLTKTQRKRSLVTSEPQHVTLIVFGIGMVNRTHLEADIGGLTMES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EPTCKVVFENEQDNSSLTKTQRKRSLVTSEPQHVTLIVFGIGMVNRTHLEADIGGLTMES 1820 1830 1840 1850 1860 1870 820 830 840 850 860 870 pF1KA1 ELKRIHGSFTLKEKMKDVLHQKMTETCATAHIGGVNIVLLEGITPNIQLEDFPTSPTSTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELKRIHGSFTLKEKMKDVLHQKMTETCATAHIGGVNIVLLEGITPNIQLEDFPTSPTSTA 1880 1890 1900 1910 1920 1930 880 890 900 910 920 930 pF1KA1 KQEFLTVVKCSIAKSQALYSAQRGLKTNNAAVFKVGAISINIPQHPATLHSMMVRSSHQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KQEFLTVVKCSIAKSQALYSAQRGLKTNNAAVFKVGAISINIPQHPATLHSMMVRSSHQL 1940 1950 1960 1970 1980 1990 940 950 960 970 980 990 pF1KA1 SKQISDLIRQPSTAPQPVKEDIATPLPSEKTPTSVNQTPVETNEFPQLPEGLEKKPIVLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKQISDLIRQPSTAPQPVKEDIATPLPSEKTPTSVNQTPVETNEFPQLPEGLEKKPIVLK 2000 2010 2020 2030 2040 2050 1000 1010 1020 1030 1040 1050 pF1KA1 FSAMLDGIAIGAALLPSLKAEYKMGRMRSHGMTGAQTRFTFELPNHRLRFTSKVSATDMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FSAMLDGIAIGAALLPSLKAEYKMGRMRSHGMTGAQTRFTFELPNHRLRFTSKVSATDMS 2060 2070 2080 2090 2100 2110 1060 1070 1080 1090 1100 1110 pF1KA1 TIPPSASLNLPPVTMSGKYIMEEHDSYSDQVWSIDELPSKQGYYLQGNYLRCVAEVGSFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TIPPSASLNLPPVTMSGKYIMEEHDSYSDQVWSIDELPSKQGYYLQGNYLRCVAEVGSFE 2120 2130 2140 2150 2160 2170 1120 1130 1140 1150 1160 1170 pF1KA1 HNLTTDLLNHLVFVQKVFMKEVNEVIQKVSGGEQPIPLWNEHDGTADGDKPKILLYSLNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HNLTTDLLNHLVFVQKVFMKEVNEVIQKVSGGEQPIPLWNEHDGTADGDKPKILLYSLNL 2180 2190 2200 2210 2220 2230 1180 1190 1200 1210 1220 1230 pF1KA1 QFKGIQVTATTPSMRAVRFETGLIELELSNRLQTKASPGSSSYLKLFGKCQVDLNLALGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QFKGIQVTATTPSMRAVRFETGLIELELSNRLQTKASPGSSSYLKLFGKCQVDLNLALGQ 2240 2250 2260 2270 2280 2290 1240 1250 1260 1270 1280 1290 pF1KA1 IVKHQVYEEAGSDFHQVAYFKTRIGLRNALREEISGSSDREAVLITLNRPIVYAQPVAFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IVKHQVYEEAGSDFHQVAYFKTRIGLRNALREEISGSSDREAVLITLNRPIVYAQPVAFD 2300 2310 2320 2330 2340 2350 1300 1310 1320 1330 1340 1350 pF1KA1 RAVLFWLNYKAAYDNWNEQRMALHKDIHMATKEVVDMLPGIQQTSAQAFGTLFLQLTVND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RAVLFWLNYKAAYDNWNEQRMALHKDIHMATKEVVDMLPGIQQTSAQAFGTLFLQLTVND 2360 2370 2380 2390 2400 2410 1360 1370 1380 1390 1400 1410 pF1KA1 LGICLPITNTAQSNHTGDLDTGSALVLTIESTLITACSSESLVSKGHFKNFCIRFADGFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGICLPITNTAQSNHTGDLDTGSALVLTIESTLITACSSESLVSKGHFKNFCIRFADGFE 2420 2430 2440 2450 2460 2470 1420 1430 1440 1450 1460 1470 pF1KA1 TSWDDWKPEIHGDLVMNACVVPDGTYEVCSRTTGQAAAESSSAGTWTLNVLWKMCGIDVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSWDDWKPEIHGDLVMNACVVPDGTYEVCSRTTGQAAAESSSAGTWTLNVLWKMCGIDVH 2480 2490 2500 2510 2520 2530 1480 1490 1500 1510 1520 pF1KA1 MDPNIGKRLNALGNTLTTLTGEEDIDDIADLNSVNIADLSDEDEVDTMSPTIHT------ :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDPNIGKRLNALGNTLTTLTGEEDIDDIADLNSVNIADLSDEDEVDTMSPTIHTSSDGSS 2540 2550 2560 2570 2580 2590 pF1KA1 ------------------------------------------------------------ XP_016 ISGDGHKLTFGQRLVNHLLGLTPPNQRHSVPAEYLCDPEMWGSPQSSQSHLKACRAHSWG 2600 2610 2620 2630 2640 2650 1530 1540 1550 1560 1570 1580 pF1KA1 -EATDYRRQAASASQPGELRGRKIMKRIVDIRELNEQAKVIDDLKKLGASEGTINQEIQR ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NEATDYRRQAASASQPGELRGRKIMKRIVDIRELNEQAKVIDDLKKLGASEGTINQEIQR 2660 2670 2680 2690 2700 2710 1590 1600 1610 1620 1630 1640 pF1KA1 YQQLESVAVNDIRRDVRKKLRRSSMRAASLKDKWGLSYKPSYSRSKSISASGRPPLKRME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YQQLESVAVNDIRRDVRKKLRRSSMRAASLKDKWGLSYKPSYSRSKSISASGRPPLKRME 2720 2730 2740 2750 2760 2770 1650 1660 1670 1680 pF1KA1 RASSRVGETEELPEIRVDAASPGPRVTFNIQDT---------------------FPEETE ::::::::::::::::::::::::::::::::: :::::: XP_016 RASSRVGETEELPEIRVDAASPGPRVTFNIQDTLKNTVWGSTPQSSCPGEGYFQFPEETE 2780 2790 2800 2810 2820 2830 1690 1700 1710 1720 1730 1740 pF1KA1 LDLLSVTIEGPSHYSSNSEGSCSVFSSPKTPGGFSPGIPFQTEEGRRDDSLSSTSEDSEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDLLSVTIEGPSHYSSNSEGSCSVFSSPKTPGGFSPGIPFQTEEGRRDDSLSSTSEDSEK 2840 2850 2860 2870 2880 2890 1750 1760 1770 1780 1790 1800 pF1KA1 DEKDEDHERERFYIYRKPSHTSRKKATGFAAVHQLFTERWPTTPVNRSLSGTATERNIDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DEKDEDHERERFYIYRKPSHTSRKKATGFAAVHQLFTERWPTTPVNRSLSGTATERNIDF 2900 2910 2920 2930 2940 2950 1810 1820 1830 1840 1850 1860 pF1KA1 ELDIRVEIDSGKCVLHPTTLLQEHDDISLRRSYDRSSRSLDQDSPSKKKKFQTNYASTTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELDIRVEIDSGKCVLHPTTLLQEHDDISLRRSYDRSSRSLDQDSPSKKKKFQTNYASTTH 2960 2970 2980 2990 3000 3010 1870 1880 1890 1900 1910 1920 pF1KA1 LMTGKKVPSSLQTKPSDLETTVFYIPGVDVKLHYNSKTLKTESPNASRGSSLPRTLSKES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LMTGKKVPSSLQTKPSDLETTVFYIPGVDVKLHYNSKTLKTESPNASRGSSLPRTLSKES 3020 3030 3040 3050 3060 3070 1930 1940 1950 1960 1970 1980 pF1KA1 KLYGMKDSATSPPSPPLPSTVQSKTNTLLPPQPPPIPAAKGKGSGGVKTAKLYAWVALQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLYGMKDSATSPPSPPLPSTVQSKTNTLLPPQPPPIPAAKGKGSGGVKTAKLYAWVALQS 3080 3090 3100 3110 3120 3130 1990 2000 2010 2020 2030 2040 pF1KA1 LPEEMVISPCLLDFLEKALETIPITPVERNYTAVSSQDEDMGHFEIPDPMEESTTSLVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPEEMVISPCLLDFLEKALETIPITPVERNYTAVSSQDEDMGHFEIPDPMEESTTSLVSS 3140 3150 3160 3170 3180 3190 2050 2060 2070 2080 2090 2100 pF1KA1 STSAYSSFPVDVVVYVRVQPSQIKFSCLPVSRVECMLKLPSLDLVFSSNRGELETLGTTY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 STSAYSSFPVDVVVYVRVQPSQIKFSCLPVSRVECMLKLPSLDLVFSSNRGELETLGTTY 3200 3210 3220 3230 3240 3250 2110 2120 2130 2140 2150 2160 pF1KA1 PAETLSPGGNATQSGTKTSASKTGIPGSSGLGSPLGRSRHSSSQSDLTSSSSSSSGLSFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PAETLSPGGNATQSGTKTSASKTGIPGSSGLGSPLGRSRHSSSQSDLTSSSSSSSGLSFT 3260 3270 3280 3290 3300 3310 2170 2180 2190 2200 2210 2220 pF1KA1 ACMSDFSLYVFHPYGAGKQKTAVSGLTPGSGGLGNVDEEPTSVTGRKDSLSINLEFVKVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ACMSDFSLYVFHPYGAGKQKTAVSGLTPGSGGLGNVDEEPTSVTGRKDSLSINLEFVKVS 3320 3330 3340 3350 3360 3370 2230 2240 2250 2260 2270 2280 pF1KA1 LSRIRRSGGASFFESQSVSKSASKMDTTLINISAVCDIGSASFKYDMRRLSEILAFPRAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSRIRRSGGASFFESQSVSKSASKMDTTLINISAVCDIGSASFKYDMRRLSEILAFPRAW 3380 3390 3400 3410 3420 3430 2290 2300 2310 2320 2330 2340 pF1KA1 YRRSIARRLFLGDQTINLPTSGPGTPDSIEGVSQHLSPESSRKAYCKTWEQPSQSASFTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YRRSIARRLFLGDQTINLPTSGPGTPDSIEGVSQHLSPESSRKAYCKTWEQPSQSASFTH 3440 3450 3460 3470 3480 3490 2350 2360 2370 2380 2390 2400 pF1KA1 MPQSPNVFNEHMTNSTMSPGTVGQSLKSPASIRSRSVSDSSVPRRDSLSKTSTPFNKSNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MPQSPNVFNEHMTNSTMSPGTVGQSLKSPASIRSRSVSDSSVPRRDSLSKTSTPFNKSNK 3500 3510 3520 3530 3540 3550 2410 2420 2430 2440 2450 2460 pF1KA1 AASQQGTPWETLVVFAINLKQLNVQMNMSNVMGNTTWTTSGLKSQGRLSVGSNRDREISM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AASQQGTPWETLVVFAINLKQLNVQMNMSNVMGNTTWTTSGLKSQGRLSVGSNRDREISM 3560 3570 3580 3590 3600 3610 2470 2480 2490 2500 2510 2520 pF1KA1 SVGLGRSQLDSKGGVVGGTIDVNALEMVAHISEHPNQQPSHKIQITMGSTEARVDYMGSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVGLGRSQLDSKGGVVGGTIDVNALEMVAHISEHPNQQPSHKIQITMGSTEARVDYMGSS 3620 3630 3640 3650 3660 3670 2530 2540 2550 2560 2570 2580 pF1KA1 ILMGIFSNADLKLQDEWKVNLYNTLDSSITDKSEIFVHGDLKWDIFQVMISRSTTPDLIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILMGIFSNADLKLQDEWKVNLYNTLDSSITDKSEIFVHGDLKWDIFQVMISRSTTPDLIK 3680 3690 3700 3710 3720 3730 2590 2600 2610 2620 2630 2640 pF1KA1 IGMKLQEFFTQQFDTSKRALSTWGPVPYLPPKTMTSNLEKSSQEQLLDAAHHRHWPGVLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IGMKLQEFFTQQFDTSKRALSTWGPVPYLPPKTMTSNLEKSSQEQLLDAAHHRHWPGVLK 3740 3750 3760 3770 3780 3790 2650 2660 2670 2680 2690 2700 pF1KA1 VVSGCHISLFQIPLPEDGMQFGGSMSLHGNHMTLACFHGPNFRSKSWALFHLEEPNIAFW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VVSGCHISLFQIPLPEDGMQFGGSMSLHGNHMTLACFHGPNFRSKSWALFHLEEPNIAFW 3800 3810 3820 3830 3840 3850 2710 2720 2730 2740 2750 2760 pF1KA1 TEAQKIWEDGSSDHSTYIVQTLDFHLGHNTMVTKPCGALESPMATITKITRRRHENPPHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TEAQKIWEDGSSDHSTYIVQTLDFHLGHNTMVTKPCGALESPMATITKITRRRHENPPHG 3860 3870 3880 3890 3900 3910 2770 2780 2790 2800 2810 2820 pF1KA1 VASVKEWFNYVTATRNEELNLLRNVDANNTENSTTVKNSSLLSGFRGGSSYNHETETIFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VASVKEWFNYVTATRNEELNLLRNVDANNTENSTTVKNSSLLSGFRGGSSYNHETETIFA 3920 3930 3940 3950 3960 3970 2830 2840 2850 2860 2870 2880 pF1KA1 LPRMQLDFKSIHVQEPQEPSLQDASLKPKVECSVVTEFTDHICVTMDAELIMFLHDLVSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPRMQLDFKSIHVQEPQEPSLQDASLKPKVECSVVTEFTDHICVTMDAELIMFLHDLVSA 3980 3990 4000 4010 4020 4030 2890 2900 2910 2920 2930 2940 pF1KA1 YLKEKEKAIFPPRILSTRPGQKSPIIIHDDNSSDKDREDSITYTTVDWRDFMCNTWHLEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLKEKEKAIFPPRILSTRPGQKSPIIIHDDNSSDKDREDSITYTTVDWRDFMCNTWHLEP 4040 4050 4060 4070 4080 4090 2950 2960 2970 2980 2990 3000 pF1KA1 TLRLISWTGRKIDPVGVDYILQKLGFHHARTTIPKWLQRGVMDPLDKVLSVLIKKLGTAL :::::::::::::::::: XP_016 TLRLISWTGRKIDPVGVDYILQKLGFHHARTTIPKWLQRGVMDPLDKVLSVLIKKLGTAL 4100 4110 4120 4130 4140 4150 >-- initn: 371 init1: 371 opt: 371 Z-score: 268.4 bits: 64.8 E(85289): 3.3e-08 Smith-Waterman score: 371; 100.0% identity (100.0% similar) in 56 aa overlap (2961-3016:4115-4170) 2940 2950 2960 2970 2980 2990 pF1KA1 RDFMCNTWHLEPTLRLISWTGRKIDPVGVDYILQKLGFHHARTTIPKWLQRGVMDPLDKV :::::::::::::::::::::::::::::: XP_016 RDFMCNTWHLEPTLRLISWTGRKIDPVGVDYILQKLGFHHARTTIPKWLQRGVMDPLDKV 4090 4100 4110 4120 4130 4140 3000 3010 pF1KA1 LSVLIKKLGTALQDEKEKKGKDKEEH :::::::::::::::::::::::::: XP_016 LSVLIKKLGTALQDEKEKKGKDKEEH 4150 4160 4170 >>XP_011530632 (OMIM: 611565) PREDICTED: uncharacterized (4510 aa) initn: 18857 init1: 10013 opt: 10017 Z-score: 7309.3 bits: 1367.7 E(85289): 0 Smith-Waterman score: 19269; 97.1% identity (97.1% similar) in 3048 aa overlap (1-2960:1407-4454) 10 20 30 pF1KA1 MPPPPDSCSMKLTIKEIWFSFAAPTNVRSH :::::::::::::::::::::::::::::: XP_011 SPSSDLNGNSVSDEQDEGVESDDLKKDLPLMPPPPDSCSMKLTIKEIWFSFAAPTNVRSH 1380 1390 1400 1410 1420 1430 40 50 60 70 80 90 pF1KA1 THAFSRQLNLLSTATPAVGAWLVPIDQLKSSLNKLETEGTLRICAVMGCIMTEALENKSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 THAFSRQLNLLSTATPAVGAWLVPIDQLKSSLNKLETEGTLRICAVMGCIMTEALENKSV 1440 1450 1460 1470 1480 1490 100 110 120 130 140 150 pF1KA1 HFPLRSKYNRLTKVARFLQENPSCLLCNILHHYLHQANYSIIDDATMSDGLPALVTLKKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HFPLRSKYNRLTKVARFLQENPSCLLCNILHHYLHQANYSIIDDATMSDGLPALVTLKKG 1500 1510 1520 1530 1540 1550 160 170 180 190 200 210 pF1KA1 LVALARQWMKFIVVTPAFKGVSLHRPAQPLKPQIAMDHEHEDGLGLDNGGGLQSDTSADG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LVALARQWMKFIVVTPAFKGVSLHRPAQPLKPQIAMDHEHEDGLGLDNGGGLQSDTSADG 1560 1570 1580 1590 1600 1610 220 230 240 250 260 270 pF1KA1 AEFEFDAATVSEHTMLLEGTANRPPPGSSGPVTGAEIMRKLSKTHTHSDSALKIKGIHPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AEFEFDAATVSEHTMLLEGTANRPPPGSSGPVTGAEIMRKLSKTHTHSDSALKIKGIHPY 1620 1630 1640 1650 1660 1670 280 290 300 310 320 330 pF1KA1 HSLSYTSGDTATDSPVHVGRAGMPVKDSPRKESLLSYLTGSFPSLHNLLEGTPQRSSAAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HSLSYTSGDTATDSPVHVGRAGMPVKDSPRKESLLSYLTGSFPSLHNLLEGTPQRSSAAV 1680 1690 1700 1710 1720 1730 340 350 360 370 380 390 pF1KA1 KSSSLTRTGNTVATDMLSEHPLLSEPSSVSFYNWMSNAVGNRGSVLQESPVTKSGHNSLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KSSSLTRTGNTVATDMLSEHPLLSEPSSVSFYNWMSNAVGNRGSVLQESPVTKSGHNSLP 1740 1750 1760 1770 1780 1790 400 410 420 430 440 450 pF1KA1 TGVAPNLPTIPSASDFNTVLSSDQNTLDGTHSQHSTSQDDVAGVEEANQGFPAVQLADAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TGVAPNLPTIPSASDFNTVLSSDQNTLDGTHSQHSTSQDDVAGVEEANQGFPAVQLADAQ 1800 1810 1820 1830 1840 1850 460 470 480 490 500 510 pF1KA1 VVFKPLLSHTGIQSQDTMPFCYRMYFGEHLSFSGTLDCLRADIVDSDTAKERKGKRARRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVFKPLLSHTGIQSQDTMPFCYRMYFGEHLSFSGTLDCLRADIVDSDTAKERKGKRARRQ 1860 1870 1880 1890 1900 1910 520 530 540 550 560 570 pF1KA1 GHVNLPPLEFKPALMLGTFSISAVVMEKSVCTPQNSTSALSFHDLSKRYYNTFHCNFTIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GHVNLPPLEFKPALMLGTFSISAVVMEKSVCTPQNSTSALSFHDLSKRYYNTFHCNFTIS 1920 1930 1940 1950 1960 1970 580 590 600 610 620 630 pF1KA1 CQSISQHVDMALVRLIHQFSTMIDDIKATQTDIKLSRYTAGSASPTPTFKTRKHRDFRSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CQSISQHVDMALVRLIHQFSTMIDDIKATQTDIKLSRYTAGSASPTPTFKTRKHRDFRSS 1980 1990 2000 2010 2020 2030 640 650 660 670 680 690 pF1KA1 DFSRSSRGSLNGGNRVNNAKNKRTNNENNKKESRNKNSLGRSERRTSKVSRKGSKDVVDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DFSRSSRGSLNGGNRVNNAKNKRTNNENNKKESRNKNSLGRSERRTSKVSRKGSKDVVDH 2040 2050 2060 2070 2080 2090 700 710 720 730 740 750 pF1KA1 MTIHMDDSDSITVSEQSEPSAECWQNMYKLLNFYSLISDPTGILEKSSETFGPAGVRSPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MTIHMDDSDSITVSEQSEPSAECWQNMYKLLNFYSLISDPTGILEKSSETFGPAGVRSPT 2100 2110 2120 2130 2140 2150 760 770 780 790 800 810 pF1KA1 EPTCKVVFENEQDNSSLTKTQRKRSLVTSEPQHVTLIVFGIGMVNRTHLEADIGGLTMES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EPTCKVVFENEQDNSSLTKTQRKRSLVTSEPQHVTLIVFGIGMVNRTHLEADIGGLTMES 2160 2170 2180 2190 2200 2210 820 830 840 850 860 870 pF1KA1 ELKRIHGSFTLKEKMKDVLHQKMTETCATAHIGGVNIVLLEGITPNIQLEDFPTSPTSTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELKRIHGSFTLKEKMKDVLHQKMTETCATAHIGGVNIVLLEGITPNIQLEDFPTSPTSTA 2220 2230 2240 2250 2260 2270 880 890 900 910 920 930 pF1KA1 KQEFLTVVKCSIAKSQALYSAQRGLKTNNAAVFKVGAISINIPQHPATLHSMMVRSSHQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KQEFLTVVKCSIAKSQALYSAQRGLKTNNAAVFKVGAISINIPQHPATLHSMMVRSSHQL 2280 2290 2300 2310 2320 2330 940 950 960 970 980 990 pF1KA1 SKQISDLIRQPSTAPQPVKEDIATPLPSEKTPTSVNQTPVETNEFPQLPEGLEKKPIVLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SKQISDLIRQPSTAPQPVKEDIATPLPSEKTPTSVNQTPVETNEFPQLPEGLEKKPIVLK 2340 2350 2360 2370 2380 2390 1000 1010 1020 1030 1040 1050 pF1KA1 FSAMLDGIAIGAALLPSLKAEYKMGRMRSHGMTGAQTRFTFELPNHRLRFTSKVSATDMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FSAMLDGIAIGAALLPSLKAEYKMGRMRSHGMTGAQTRFTFELPNHRLRFTSKVSATDMS 2400 2410 2420 2430 2440 2450 1060 1070 1080 1090 1100 1110 pF1KA1 TIPPSASLNLPPVTMSGKYIMEEHDSYSDQVWSIDELPSKQGYYLQGNYLRCVAEVGSFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TIPPSASLNLPPVTMSGKYIMEEHDSYSDQVWSIDELPSKQGYYLQGNYLRCVAEVGSFE 2460 2470 2480 2490 2500 2510 1120 1130 1140 1150 1160 1170 pF1KA1 HNLTTDLLNHLVFVQKVFMKEVNEVIQKVSGGEQPIPLWNEHDGTADGDKPKILLYSLNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HNLTTDLLNHLVFVQKVFMKEVNEVIQKVSGGEQPIPLWNEHDGTADGDKPKILLYSLNL 2520 2530 2540 2550 2560 2570 1180 1190 1200 1210 1220 1230 pF1KA1 QFKGIQVTATTPSMRAVRFETGLIELELSNRLQTKASPGSSSYLKLFGKCQVDLNLALGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QFKGIQVTATTPSMRAVRFETGLIELELSNRLQTKASPGSSSYLKLFGKCQVDLNLALGQ 2580 2590 2600 2610 2620 2630 1240 1250 1260 1270 1280 1290 pF1KA1 IVKHQVYEEAGSDFHQVAYFKTRIGLRNALREEISGSSDREAVLITLNRPIVYAQPVAFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IVKHQVYEEAGSDFHQVAYFKTRIGLRNALREEISGSSDREAVLITLNRPIVYAQPVAFD 2640 2650 2660 2670 2680 2690 1300 1310 1320 1330 1340 1350 pF1KA1 RAVLFWLNYKAAYDNWNEQRMALHKDIHMATKEVVDMLPGIQQTSAQAFGTLFLQLTVND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RAVLFWLNYKAAYDNWNEQRMALHKDIHMATKEVVDMLPGIQQTSAQAFGTLFLQLTVND 2700 2710 2720 2730 2740 2750 1360 1370 1380 1390 1400 1410 pF1KA1 LGICLPITNTAQSNHTGDLDTGSALVLTIESTLITACSSESLVSKGHFKNFCIRFADGFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LGICLPITNTAQSNHTGDLDTGSALVLTIESTLITACSSESLVSKGHFKNFCIRFADGFE 2760 2770 2780 2790 2800 2810 1420 1430 1440 1450 1460 1470 pF1KA1 TSWDDWKPEIHGDLVMNACVVPDGTYEVCSRTTGQAAAESSSAGTWTLNVLWKMCGIDVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSWDDWKPEIHGDLVMNACVVPDGTYEVCSRTTGQAAAESSSAGTWTLNVLWKMCGIDVH 2820 2830 2840 2850 2860 2870 1480 1490 1500 1510 1520 pF1KA1 MDPNIGKRLNALGNTLTTLTGEEDIDDIADLNSVNIADLSDEDEVDTMSPTIHT------ :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MDPNIGKRLNALGNTLTTLTGEEDIDDIADLNSVNIADLSDEDEVDTMSPTIHTSSDGSS 2880 2890 2900 2910 2920 2930 pF1KA1 ------------------------------------------------------------ XP_011 ISGDGHKLTFGQRLVNHLLGLTPPNQRHSVPAEYLCDPEMWGSPQSSQSHLKACRAHSWG 2940 2950 2960 2970 2980 2990 1530 1540 1550 1560 1570 1580 pF1KA1 -EATDYRRQAASASQPGELRGRKIMKRIVDIRELNEQAKVIDDLKKLGASEGTINQEIQR ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NEATDYRRQAASASQPGELRGRKIMKRIVDIRELNEQAKVIDDLKKLGASEGTINQEIQR 3000 3010 3020 3030 3040 3050 1590 1600 1610 1620 1630 1640 pF1KA1 YQQLESVAVNDIRRDVRKKLRRSSMRAASLKDKWGLSYKPSYSRSKSISASGRPPLKRME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YQQLESVAVNDIRRDVRKKLRRSSMRAASLKDKWGLSYKPSYSRSKSISASGRPPLKRME 3060 3070 3080 3090 3100 3110 1650 1660 1670 1680 pF1KA1 RASSRVGETEELPEIRVDAASPGPRVTFNIQDT---------------------FPEETE ::::::::::::::::::::::::::::::::: :::::: XP_011 RASSRVGETEELPEIRVDAASPGPRVTFNIQDTLKNTVWGSTPQSSCPGEGYFQFPEETE 3120 3130 3140 3150 3160 3170 1690 1700 1710 1720 1730 1740 pF1KA1 LDLLSVTIEGPSHYSSNSEGSCSVFSSPKTPGGFSPGIPFQTEEGRRDDSLSSTSEDSEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDLLSVTIEGPSHYSSNSEGSCSVFSSPKTPGGFSPGIPFQTEEGRRDDSLSSTSEDSEK 3180 3190 3200 3210 3220 3230 1750 1760 1770 1780 1790 1800 pF1KA1 DEKDEDHERERFYIYRKPSHTSRKKATGFAAVHQLFTERWPTTPVNRSLSGTATERNIDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DEKDEDHERERFYIYRKPSHTSRKKATGFAAVHQLFTERWPTTPVNRSLSGTATERNIDF 3240 3250 3260 3270 3280 3290 1810 1820 1830 1840 1850 1860 pF1KA1 ELDIRVEIDSGKCVLHPTTLLQEHDDISLRRSYDRSSRSLDQDSPSKKKKFQTNYASTTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELDIRVEIDSGKCVLHPTTLLQEHDDISLRRSYDRSSRSLDQDSPSKKKKFQTNYASTTH 3300 3310 3320 3330 3340 3350 1870 1880 1890 1900 1910 1920 pF1KA1 LMTGKKVPSSLQTKPSDLETTVFYIPGVDVKLHYNSKTLKTESPNASRGSSLPRTLSKES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LMTGKKVPSSLQTKPSDLETTVFYIPGVDVKLHYNSKTLKTESPNASRGSSLPRTLSKES 3360 3370 3380 3390 3400 3410 1930 1940 1950 1960 1970 1980 pF1KA1 KLYGMKDSATSPPSPPLPSTVQSKTNTLLPPQPPPIPAAKGKGSGGVKTAKLYAWVALQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLYGMKDSATSPPSPPLPSTVQSKTNTLLPPQPPPIPAAKGKGSGGVKTAKLYAWVALQS 3420 3430 3440 3450 3460 3470 1990 2000 2010 2020 2030 2040 pF1KA1 LPEEMVISPCLLDFLEKALETIPITPVERNYTAVSSQDEDMGHFEIPDPMEESTTSLVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPEEMVISPCLLDFLEKALETIPITPVERNYTAVSSQDEDMGHFEIPDPMEESTTSLVSS 3480 3490 3500 3510 3520 3530 2050 2060 2070 2080 2090 2100 pF1KA1 STSAYSSFPVDVVVYVRVQPSQIKFSCLPVSRVECMLKLPSLDLVFSSNRGELETLGTTY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STSAYSSFPVDVVVYVRVQPSQIKFSCLPVSRVECMLKLPSLDLVFSSNRGELETLGTTY 3540 3550 3560 3570 3580 3590 2110 2120 2130 2140 2150 2160 pF1KA1 PAETLSPGGNATQSGTKTSASKTGIPGSSGLGSPLGRSRHSSSQSDLTSSSSSSSGLSFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PAETLSPGGNATQSGTKTSASKTGIPGSSGLGSPLGRSRHSSSQSDLTSSSSSSSGLSFT 3600 3610 3620 3630 3640 3650 2170 2180 2190 2200 2210 2220 pF1KA1 ACMSDFSLYVFHPYGAGKQKTAVSGLTPGSGGLGNVDEEPTSVTGRKDSLSINLEFVKVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ACMSDFSLYVFHPYGAGKQKTAVSGLTPGSGGLGNVDEEPTSVTGRKDSLSINLEFVKVS 3660 3670 3680 3690 3700 3710 2230 2240 2250 2260 2270 2280 pF1KA1 LSRIRRSGGASFFESQSVSKSASKMDTTLINISAVCDIGSASFKYDMRRLSEILAFPRAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSRIRRSGGASFFESQSVSKSASKMDTTLINISAVCDIGSASFKYDMRRLSEILAFPRAW 3720 3730 3740 3750 3760 3770 2290 2300 2310 2320 2330 2340 pF1KA1 YRRSIARRLFLGDQTINLPTSGPGTPDSIEGVSQHLSPESSRKAYCKTWEQPSQSASFTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YRRSIARRLFLGDQTINLPTSGPGTPDSIEGVSQHLSPESSRKAYCKTWEQPSQSASFTH 3780 3790 3800 3810 3820 3830 2350 2360 2370 2380 2390 2400 pF1KA1 MPQSPNVFNEHMTNSTMSPGTVGQSLKSPASIRSRSVSDSSVPRRDSLSKTSTPFNKSNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MPQSPNVFNEHMTNSTMSPGTVGQSLKSPASIRSRSVSDSSVPRRDSLSKTSTPFNKSNK 3840 3850 3860 3870 3880 3890 2410 2420 2430 2440 2450 2460 pF1KA1 AASQQGTPWETLVVFAINLKQLNVQMNMSNVMGNTTWTTSGLKSQGRLSVGSNRDREISM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AASQQGTPWETLVVFAINLKQLNVQMNMSNVMGNTTWTTSGLKSQGRLSVGSNRDREISM 3900 3910 3920 3930 3940 3950 2470 2480 2490 2500 2510 2520 pF1KA1 SVGLGRSQLDSKGGVVGGTIDVNALEMVAHISEHPNQQPSHKIQITMGSTEARVDYMGSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SVGLGRSQLDSKGGVVGGTIDVNALEMVAHISEHPNQQPSHKIQITMGSTEARVDYMGSS 3960 3970 3980 3990 4000 4010 2530 2540 2550 2560 2570 2580 pF1KA1 ILMGIFSNADLKLQDEWKVNLYNTLDSSITDKSEIFVHGDLKWDIFQVMISRSTTPDLIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILMGIFSNADLKLQDEWKVNLYNTLDSSITDKSEIFVHGDLKWDIFQVMISRSTTPDLIK 4020 4030 4040 4050 4060 4070 2590 2600 2610 2620 2630 2640 pF1KA1 IGMKLQEFFTQQFDTSKRALSTWGPVPYLPPKTMTSNLEKSSQEQLLDAAHHRHWPGVLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IGMKLQEFFTQQFDTSKRALSTWGPVPYLPPKTMTSNLEKSSQEQLLDAAHHRHWPGVLK 4080 4090 4100 4110 4120 4130 2650 2660 2670 2680 2690 2700 pF1KA1 VVSGCHISLFQIPLPEDGMQFGGSMSLHGNHMTLACFHGPNFRSKSWALFHLEEPNIAFW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVSGCHISLFQIPLPEDGMQFGGSMSLHGNHMTLACFHGPNFRSKSWALFHLEEPNIAFW 4140 4150 4160 4170 4180 4190 2710 2720 2730 2740 2750 2760 pF1KA1 TEAQKIWEDGSSDHSTYIVQTLDFHLGHNTMVTKPCGALESPMATITKITRRRHENPPHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TEAQKIWEDGSSDHSTYIVQTLDFHLGHNTMVTKPCGALESPMATITKITRRRHENPPHG 4200 4210 4220 4230 4240 4250 2770 2780 2790 2800 2810 2820 pF1KA1 VASVKEWFNYVTATRNEELNLLRNVDANNTENSTTVKNSSLLSGFRGGSSYNHETETIFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VASVKEWFNYVTATRNEELNLLRNVDANNTENSTTVKNSSLLSGFRGGSSYNHETETIFA 4260 4270 4280 4290 4300 4310 2830 2840 2850 2860 2870 2880 pF1KA1 LPRMQLDFKSIHVQEPQEPSLQDASLKPKVECSVVTEFTDHICVTMDAELIMFLHDLVSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPRMQLDFKSIHVQEPQEPSLQDASLKPKVECSVVTEFTDHICVTMDAELIMFLHDLVSA 4320 4330 4340 4350 4360 4370 2890 2900 2910 2920 2930 2940 pF1KA1 YLKEKEKAIFPPRILSTRPGQKSPIIIHDDNSSDKDREDSITYTTVDWRDFMCNTWHLEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YLKEKEKAIFPPRILSTRPGQKSPIIIHDDNSSDKDREDSITYTTVDWRDFMCNTWHLEP 4380 4390 4400 4410 4420 4430 2950 2960 2970 2980 2990 3000 pF1KA1 TLRLISWTGRKIDPVGVDYILQKLGFHHARTTIPKWLQRGVMDPLDKVLSVLIKKLGTAL :::::::::::::::::: XP_011 TLRLISWTGRKIDPVGVDYILQKLGFHHARTTIPKWLQRGVMDPLDKVLSVLIKKLGTAL 4440 4450 4460 4470 4480 4490 >-- initn: 371 init1: 371 opt: 371 Z-score: 267.9 bits: 64.9 E(85289): 3.5e-08 Smith-Waterman score: 371; 100.0% identity (100.0% similar) in 56 aa overlap (2961-3016:4455-4510) 2940 2950 2960 2970 2980 2990 pF1KA1 RDFMCNTWHLEPTLRLISWTGRKIDPVGVDYILQKLGFHHARTTIPKWLQRGVMDPLDKV :::::::::::::::::::::::::::::: XP_011 RDFMCNTWHLEPTLRLISWTGRKIDPVGVDYILQKLGFHHARTTIPKWLQRGVMDPLDKV 4430 4440 4450 4460 4470 4480 3000 3010 pF1KA1 LSVLIKKLGTALQDEKEKKGKDKEEH :::::::::::::::::::::::::: XP_011 LSVLIKKLGTALQDEKEKKGKDKEEH 4490 4500 4510 >>XP_011530629 (OMIM: 611565) PREDICTED: uncharacterized (5043 aa) initn: 18857 init1: 10013 opt: 10017 Z-score: 7308.6 bits: 1367.8 E(85289): 0 Smith-Waterman score: 19269; 97.1% identity (97.1% similar) in 3048 aa overlap (1-2960:1940-4987) 10 20 30 pF1KA1 MPPPPDSCSMKLTIKEIWFSFAAPTNVRSH :::::::::::::::::::::::::::::: XP_011 SPSSDLNGNSVSDEQDEGVESDDLKKDLPLMPPPPDSCSMKLTIKEIWFSFAAPTNVRSH 1910 1920 1930 1940 1950 1960 40 50 60 70 80 90 pF1KA1 THAFSRQLNLLSTATPAVGAWLVPIDQLKSSLNKLETEGTLRICAVMGCIMTEALENKSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 THAFSRQLNLLSTATPAVGAWLVPIDQLKSSLNKLETEGTLRICAVMGCIMTEALENKSV 1970 1980 1990 2000 2010 2020 100 110 120 130 140 150 pF1KA1 HFPLRSKYNRLTKVARFLQENPSCLLCNILHHYLHQANYSIIDDATMSDGLPALVTLKKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HFPLRSKYNRLTKVARFLQENPSCLLCNILHHYLHQANYSIIDDATMSDGLPALVTLKKG 2030 2040 2050 2060 2070 2080 160 170 180 190 200 210 pF1KA1 LVALARQWMKFIVVTPAFKGVSLHRPAQPLKPQIAMDHEHEDGLGLDNGGGLQSDTSADG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LVALARQWMKFIVVTPAFKGVSLHRPAQPLKPQIAMDHEHEDGLGLDNGGGLQSDTSADG 2090 2100 2110 2120 2130 2140 220 230 240 250 260 270 pF1KA1 AEFEFDAATVSEHTMLLEGTANRPPPGSSGPVTGAEIMRKLSKTHTHSDSALKIKGIHPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AEFEFDAATVSEHTMLLEGTANRPPPGSSGPVTGAEIMRKLSKTHTHSDSALKIKGIHPY 2150 2160 2170 2180 2190 2200 280 290 300 310 320 330 pF1KA1 HSLSYTSGDTATDSPVHVGRAGMPVKDSPRKESLLSYLTGSFPSLHNLLEGTPQRSSAAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HSLSYTSGDTATDSPVHVGRAGMPVKDSPRKESLLSYLTGSFPSLHNLLEGTPQRSSAAV 2210 2220 2230 2240 2250 2260 340 350 360 370 380 390 pF1KA1 KSSSLTRTGNTVATDMLSEHPLLSEPSSVSFYNWMSNAVGNRGSVLQESPVTKSGHNSLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KSSSLTRTGNTVATDMLSEHPLLSEPSSVSFYNWMSNAVGNRGSVLQESPVTKSGHNSLP 2270 2280 2290 2300 2310 2320 400 410 420 430 440 450 pF1KA1 TGVAPNLPTIPSASDFNTVLSSDQNTLDGTHSQHSTSQDDVAGVEEANQGFPAVQLADAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TGVAPNLPTIPSASDFNTVLSSDQNTLDGTHSQHSTSQDDVAGVEEANQGFPAVQLADAQ 2330 2340 2350 2360 2370 2380 460 470 480 490 500 510 pF1KA1 VVFKPLLSHTGIQSQDTMPFCYRMYFGEHLSFSGTLDCLRADIVDSDTAKERKGKRARRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVFKPLLSHTGIQSQDTMPFCYRMYFGEHLSFSGTLDCLRADIVDSDTAKERKGKRARRQ 2390 2400 2410 2420 2430 2440 520 530 540 550 560 570 pF1KA1 GHVNLPPLEFKPALMLGTFSISAVVMEKSVCTPQNSTSALSFHDLSKRYYNTFHCNFTIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GHVNLPPLEFKPALMLGTFSISAVVMEKSVCTPQNSTSALSFHDLSKRYYNTFHCNFTIS 2450 2460 2470 2480 2490 2500 580 590 600 610 620 630 pF1KA1 CQSISQHVDMALVRLIHQFSTMIDDIKATQTDIKLSRYTAGSASPTPTFKTRKHRDFRSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CQSISQHVDMALVRLIHQFSTMIDDIKATQTDIKLSRYTAGSASPTPTFKTRKHRDFRSS 2510 2520 2530 2540 2550 2560 640 650 660 670 680 690 pF1KA1 DFSRSSRGSLNGGNRVNNAKNKRTNNENNKKESRNKNSLGRSERRTSKVSRKGSKDVVDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DFSRSSRGSLNGGNRVNNAKNKRTNNENNKKESRNKNSLGRSERRTSKVSRKGSKDVVDH 2570 2580 2590 2600 2610 2620 700 710 720 730 740 750 pF1KA1 MTIHMDDSDSITVSEQSEPSAECWQNMYKLLNFYSLISDPTGILEKSSETFGPAGVRSPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MTIHMDDSDSITVSEQSEPSAECWQNMYKLLNFYSLISDPTGILEKSSETFGPAGVRSPT 2630 2640 2650 2660 2670 2680 760 770 780 790 800 810 pF1KA1 EPTCKVVFENEQDNSSLTKTQRKRSLVTSEPQHVTLIVFGIGMVNRTHLEADIGGLTMES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EPTCKVVFENEQDNSSLTKTQRKRSLVTSEPQHVTLIVFGIGMVNRTHLEADIGGLTMES 2690 2700 2710 2720 2730 2740 820 830 840 850 860 870 pF1KA1 ELKRIHGSFTLKEKMKDVLHQKMTETCATAHIGGVNIVLLEGITPNIQLEDFPTSPTSTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELKRIHGSFTLKEKMKDVLHQKMTETCATAHIGGVNIVLLEGITPNIQLEDFPTSPTSTA 2750 2760 2770 2780 2790 2800 880 890 900 910 920 930 pF1KA1 KQEFLTVVKCSIAKSQALYSAQRGLKTNNAAVFKVGAISINIPQHPATLHSMMVRSSHQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KQEFLTVVKCSIAKSQALYSAQRGLKTNNAAVFKVGAISINIPQHPATLHSMMVRSSHQL 2810 2820 2830 2840 2850 2860 940 950 960 970 980 990 pF1KA1 SKQISDLIRQPSTAPQPVKEDIATPLPSEKTPTSVNQTPVETNEFPQLPEGLEKKPIVLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SKQISDLIRQPSTAPQPVKEDIATPLPSEKTPTSVNQTPVETNEFPQLPEGLEKKPIVLK 2870 2880 2890 2900 2910 2920 1000 1010 1020 1030 1040 1050 pF1KA1 FSAMLDGIAIGAALLPSLKAEYKMGRMRSHGMTGAQTRFTFELPNHRLRFTSKVSATDMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FSAMLDGIAIGAALLPSLKAEYKMGRMRSHGMTGAQTRFTFELPNHRLRFTSKVSATDMS 2930 2940 2950 2960 2970 2980 1060 1070 1080 1090 1100 1110 pF1KA1 TIPPSASLNLPPVTMSGKYIMEEHDSYSDQVWSIDELPSKQGYYLQGNYLRCVAEVGSFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TIPPSASLNLPPVTMSGKYIMEEHDSYSDQVWSIDELPSKQGYYLQGNYLRCVAEVGSFE 2990 3000 3010 3020 3030 3040 1120 1130 1140 1150 1160 1170 pF1KA1 HNLTTDLLNHLVFVQKVFMKEVNEVIQKVSGGEQPIPLWNEHDGTADGDKPKILLYSLNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HNLTTDLLNHLVFVQKVFMKEVNEVIQKVSGGEQPIPLWNEHDGTADGDKPKILLYSLNL 3050 3060 3070 3080 3090 3100 1180 1190 1200 1210 1220 1230 pF1KA1 QFKGIQVTATTPSMRAVRFETGLIELELSNRLQTKASPGSSSYLKLFGKCQVDLNLALGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QFKGIQVTATTPSMRAVRFETGLIELELSNRLQTKASPGSSSYLKLFGKCQVDLNLALGQ 3110 3120 3130 3140 3150 3160 1240 1250 1260 1270 1280 1290 pF1KA1 IVKHQVYEEAGSDFHQVAYFKTRIGLRNALREEISGSSDREAVLITLNRPIVYAQPVAFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IVKHQVYEEAGSDFHQVAYFKTRIGLRNALREEISGSSDREAVLITLNRPIVYAQPVAFD 3170 3180 3190 3200 3210 3220 1300 1310 1320 1330 1340 1350 pF1KA1 RAVLFWLNYKAAYDNWNEQRMALHKDIHMATKEVVDMLPGIQQTSAQAFGTLFLQLTVND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RAVLFWLNYKAAYDNWNEQRMALHKDIHMATKEVVDMLPGIQQTSAQAFGTLFLQLTVND 3230 3240 3250 3260 3270 3280 1360 1370 1380 1390 1400 1410 pF1KA1 LGICLPITNTAQSNHTGDLDTGSALVLTIESTLITACSSESLVSKGHFKNFCIRFADGFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LGICLPITNTAQSNHTGDLDTGSALVLTIESTLITACSSESLVSKGHFKNFCIRFADGFE 3290 3300 3310 3320 3330 3340 1420 1430 1440 1450 1460 1470 pF1KA1 TSWDDWKPEIHGDLVMNACVVPDGTYEVCSRTTGQAAAESSSAGTWTLNVLWKMCGIDVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSWDDWKPEIHGDLVMNACVVPDGTYEVCSRTTGQAAAESSSAGTWTLNVLWKMCGIDVH 3350 3360 3370 3380 3390 3400 1480 1490 1500 1510 1520 pF1KA1 MDPNIGKRLNALGNTLTTLTGEEDIDDIADLNSVNIADLSDEDEVDTMSPTIHT------ :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MDPNIGKRLNALGNTLTTLTGEEDIDDIADLNSVNIADLSDEDEVDTMSPTIHTSSDGSS 3410 3420 3430 3440 3450 3460 pF1KA1 ------------------------------------------------------------ XP_011 ISGDGHKLTFGQRLVNHLLGLTPPNQRHSVPAEYLCDPEMWGSPQSSQSHLKACRAHSWG 3470 3480 3490 3500 3510 3520 1530 1540 1550 1560 1570 1580 pF1KA1 -EATDYRRQAASASQPGELRGRKIMKRIVDIRELNEQAKVIDDLKKLGASEGTINQEIQR ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NEATDYRRQAASASQPGELRGRKIMKRIVDIRELNEQAKVIDDLKKLGASEGTINQEIQR 3530 3540 3550 3560 3570 3580 1590 1600 1610 1620 1630 1640 pF1KA1 YQQLESVAVNDIRRDVRKKLRRSSMRAASLKDKWGLSYKPSYSRSKSISASGRPPLKRME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YQQLESVAVNDIRRDVRKKLRRSSMRAASLKDKWGLSYKPSYSRSKSISASGRPPLKRME 3590 3600 3610 3620 3630 3640 1650 1660 1670 1680 pF1KA1 RASSRVGETEELPEIRVDAASPGPRVTFNIQDT---------------------FPEETE ::::::::::::::::::::::::::::::::: :::::: XP_011 RASSRVGETEELPEIRVDAASPGPRVTFNIQDTLKNTVWGSTPQSSCPGEGYFQFPEETE 3650 3660 3670 3680 3690 3700 1690 1700 1710 1720 1730 1740 pF1KA1 LDLLSVTIEGPSHYSSNSEGSCSVFSSPKTPGGFSPGIPFQTEEGRRDDSLSSTSEDSEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDLLSVTIEGPSHYSSNSEGSCSVFSSPKTPGGFSPGIPFQTEEGRRDDSLSSTSEDSEK 3710 3720 3730 3740 3750 3760 1750 1760 1770 1780 1790 1800 pF1KA1 DEKDEDHERERFYIYRKPSHTSRKKATGFAAVHQLFTERWPTTPVNRSLSGTATERNIDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DEKDEDHERERFYIYRKPSHTSRKKATGFAAVHQLFTERWPTTPVNRSLSGTATERNIDF 3770 3780 3790 3800 3810 3820 1810 1820 1830 1840 1850 1860 pF1KA1 ELDIRVEIDSGKCVLHPTTLLQEHDDISLRRSYDRSSRSLDQDSPSKKKKFQTNYASTTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELDIRVEIDSGKCVLHPTTLLQEHDDISLRRSYDRSSRSLDQDSPSKKKKFQTNYASTTH 3830 3840 3850 3860 3870 3880 1870 1880 1890 1900 1910 1920 pF1KA1 LMTGKKVPSSLQTKPSDLETTVFYIPGVDVKLHYNSKTLKTESPNASRGSSLPRTLSKES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LMTGKKVPSSLQTKPSDLETTVFYIPGVDVKLHYNSKTLKTESPNASRGSSLPRTLSKES 3890 3900 3910 3920 3930 3940 1930 1940 1950 1960 1970 1980 pF1KA1 KLYGMKDSATSPPSPPLPSTVQSKTNTLLPPQPPPIPAAKGKGSGGVKTAKLYAWVALQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLYGMKDSATSPPSPPLPSTVQSKTNTLLPPQPPPIPAAKGKGSGGVKTAKLYAWVALQS 3950 3960 3970 3980 3990 4000 1990 2000 2010 2020 2030 2040 pF1KA1 LPEEMVISPCLLDFLEKALETIPITPVERNYTAVSSQDEDMGHFEIPDPMEESTTSLVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPEEMVISPCLLDFLEKALETIPITPVERNYTAVSSQDEDMGHFEIPDPMEESTTSLVSS 4010 4020 4030 4040 4050 4060 2050 2060 2070 2080 2090 2100 pF1KA1 STSAYSSFPVDVVVYVRVQPSQIKFSCLPVSRVECMLKLPSLDLVFSSNRGELETLGTTY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STSAYSSFPVDVVVYVRVQPSQIKFSCLPVSRVECMLKLPSLDLVFSSNRGELETLGTTY 4070 4080 4090 4100 4110 4120 2110 2120 2130 2140 2150 2160 pF1KA1 PAETLSPGGNATQSGTKTSASKTGIPGSSGLGSPLGRSRHSSSQSDLTSSSSSSSGLSFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PAETLSPGGNATQSGTKTSASKTGIPGSSGLGSPLGRSRHSSSQSDLTSSSSSSSGLSFT 4130 4140 4150 4160 4170 4180 2170 2180 2190 2200 2210 2220 pF1KA1 ACMSDFSLYVFHPYGAGKQKTAVSGLTPGSGGLGNVDEEPTSVTGRKDSLSINLEFVKVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ACMSDFSLYVFHPYGAGKQKTAVSGLTPGSGGLGNVDEEPTSVTGRKDSLSINLEFVKVS 4190 4200 4210 4220 4230 4240 2230 2240 2250 2260 2270 2280 pF1KA1 LSRIRRSGGASFFESQSVSKSASKMDTTLINISAVCDIGSASFKYDMRRLSEILAFPRAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSRIRRSGGASFFESQSVSKSASKMDTTLINISAVCDIGSASFKYDMRRLSEILAFPRAW 4250 4260 4270 4280 4290 4300 2290 2300 2310 2320 2330 2340 pF1KA1 YRRSIARRLFLGDQTINLPTSGPGTPDSIEGVSQHLSPESSRKAYCKTWEQPSQSASFTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YRRSIARRLFLGDQTINLPTSGPGTPDSIEGVSQHLSPESSRKAYCKTWEQPSQSASFTH 4310 4320 4330 4340 4350 4360 2350 2360 2370 2380 2390 2400 pF1KA1 MPQSPNVFNEHMTNSTMSPGTVGQSLKSPASIRSRSVSDSSVPRRDSLSKTSTPFNKSNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MPQSPNVFNEHMTNSTMSPGTVGQSLKSPASIRSRSVSDSSVPRRDSLSKTSTPFNKSNK 4370 4380 4390 4400 4410 4420 2410 2420 2430 2440 2450 2460 pF1KA1 AASQQGTPWETLVVFAINLKQLNVQMNMSNVMGNTTWTTSGLKSQGRLSVGSNRDREISM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AASQQGTPWETLVVFAINLKQLNVQMNMSNVMGNTTWTTSGLKSQGRLSVGSNRDREISM 4430 4440 4450 4460 4470 4480 2470 2480 2490 2500 2510 2520 pF1KA1 SVGLGRSQLDSKGGVVGGTIDVNALEMVAHISEHPNQQPSHKIQITMGSTEARVDYMGSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SVGLGRSQLDSKGGVVGGTIDVNALEMVAHISEHPNQQPSHKIQITMGSTEARVDYMGSS 4490 4500 4510 4520 4530 4540 2530 2540 2550 2560 2570 2580 pF1KA1 ILMGIFSNADLKLQDEWKVNLYNTLDSSITDKSEIFVHGDLKWDIFQVMISRSTTPDLIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILMGIFSNADLKLQDEWKVNLYNTLDSSITDKSEIFVHGDLKWDIFQVMISRSTTPDLIK 4550 4560 4570 4580 4590 4600 2590 2600 2610 2620 2630 2640 pF1KA1 IGMKLQEFFTQQFDTSKRALSTWGPVPYLPPKTMTSNLEKSSQEQLLDAAHHRHWPGVLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IGMKLQEFFTQQFDTSKRALSTWGPVPYLPPKTMTSNLEKSSQEQLLDAAHHRHWPGVLK 4610 4620 4630 4640 4650 4660 2650 2660 2670 2680 2690 2700 pF1KA1 VVSGCHISLFQIPLPEDGMQFGGSMSLHGNHMTLACFHGPNFRSKSWALFHLEEPNIAFW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVSGCHISLFQIPLPEDGMQFGGSMSLHGNHMTLACFHGPNFRSKSWALFHLEEPNIAFW 4670 4680 4690 4700 4710 4720 2710 2720 2730 2740 2750 2760 pF1KA1 TEAQKIWEDGSSDHSTYIVQTLDFHLGHNTMVTKPCGALESPMATITKITRRRHENPPHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TEAQKIWEDGSSDHSTYIVQTLDFHLGHNTMVTKPCGALESPMATITKITRRRHENPPHG 4730 4740 4750 4760 4770 4780 2770 2780 2790 2800 2810 2820 pF1KA1 VASVKEWFNYVTATRNEELNLLRNVDANNTENSTTVKNSSLLSGFRGGSSYNHETETIFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VASVKEWFNYVTATRNEELNLLRNVDANNTENSTTVKNSSLLSGFRGGSSYNHETETIFA 4790 4800 4810 4820 4830 4840 2830 2840 2850 2860 2870 2880 pF1KA1 LPRMQLDFKSIHVQEPQEPSLQDASLKPKVECSVVTEFTDHICVTMDAELIMFLHDLVSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPRMQLDFKSIHVQEPQEPSLQDASLKPKVECSVVTEFTDHICVTMDAELIMFLHDLVSA 4850 4860 4870 4880 4890 4900 2890 2900 2910 2920 2930 2940 pF1KA1 YLKEKEKAIFPPRILSTRPGQKSPIIIHDDNSSDKDREDSITYTTVDWRDFMCNTWHLEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YLKEKEKAIFPPRILSTRPGQKSPIIIHDDNSSDKDREDSITYTTVDWRDFMCNTWHLEP 4910 4920 4930 4940 4950 4960 2950 2960 2970 2980 2990 3000 pF1KA1 TLRLISWTGRKIDPVGVDYILQKLGFHHARTTIPKWLQRGVMDPLDKVLSVLIKKLGTAL :::::::::::::::::: XP_011 TLRLISWTGRKIDPVGVDYILQKLGFHHARTTIPKWLQRGVMDPLDKVLSVLIKKLGTAL 4970 4980 4990 5000 5010 5020 >-- initn: 371 init1: 371 opt: 371 Z-score: 267.2 bits: 64.9 E(85289): 3.8e-08 Smith-Waterman score: 371; 100.0% identity (100.0% similar) in 56 aa overlap (2961-3016:4988-5043) 2940 2950 2960 2970 2980 2990 pF1KA1 RDFMCNTWHLEPTLRLISWTGRKIDPVGVDYILQKLGFHHARTTIPKWLQRGVMDPLDKV :::::::::::::::::::::::::::::: XP_011 RDFMCNTWHLEPTLRLISWTGRKIDPVGVDYILQKLGFHHARTTIPKWLQRGVMDPLDKV 4960 4970 4980 4990 5000 5010 3000 3010 pF1KA1 LSVLIKKLGTALQDEKEKKGKDKEEH :::::::::::::::::::::::::: XP_011 LSVLIKKLGTALQDEKEKKGKDKEEH 5020 5030 5040 >>XP_011530628 (OMIM: 611565) PREDICTED: uncharacterized (5050 aa) initn: 18857 init1: 10013 opt: 10017 Z-score: 7308.6 bits: 1367.8 E(85289): 0 Smith-Waterman score: 19269; 97.1% identity (97.1% similar) in 3048 aa overlap (1-2960:1947-4994) 10 20 30 pF1KA1 MPPPPDSCSMKLTIKEIWFSFAAPTNVRSH :::::::::::::::::::::::::::::: XP_011 SPSSDLNGNSVSDEQDEGVESDDLKKDLPLMPPPPDSCSMKLTIKEIWFSFAAPTNVRSH 1920 1930 1940 1950 1960 1970 40 50 60 70 80 90 pF1KA1 THAFSRQLNLLSTATPAVGAWLVPIDQLKSSLNKLETEGTLRICAVMGCIMTEALENKSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 THAFSRQLNLLSTATPAVGAWLVPIDQLKSSLNKLETEGTLRICAVMGCIMTEALENKSV 1980 1990 2000 2010 2020 2030 100 110 120 130 140 150 pF1KA1 HFPLRSKYNRLTKVARFLQENPSCLLCNILHHYLHQANYSIIDDATMSDGLPALVTLKKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HFPLRSKYNRLTKVARFLQENPSCLLCNILHHYLHQANYSIIDDATMSDGLPALVTLKKG 2040 2050 2060 2070 2080 2090 160 170 180 190 200 210 pF1KA1 LVALARQWMKFIVVTPAFKGVSLHRPAQPLKPQIAMDHEHEDGLGLDNGGGLQSDTSADG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LVALARQWMKFIVVTPAFKGVSLHRPAQPLKPQIAMDHEHEDGLGLDNGGGLQSDTSADG 2100 2110 2120 2130 2140 2150 220 230 240 250 260 270 pF1KA1 AEFEFDAATVSEHTMLLEGTANRPPPGSSGPVTGAEIMRKLSKTHTHSDSALKIKGIHPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AEFEFDAATVSEHTMLLEGTANRPPPGSSGPVTGAEIMRKLSKTHTHSDSALKIKGIHPY 2160 2170 2180 2190 2200 2210 280 290 300 310 320 330 pF1KA1 HSLSYTSGDTATDSPVHVGRAGMPVKDSPRKESLLSYLTGSFPSLHNLLEGTPQRSSAAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HSLSYTSGDTATDSPVHVGRAGMPVKDSPRKESLLSYLTGSFPSLHNLLEGTPQRSSAAV 2220 2230 2240 2250 2260 2270 340 350 360 370 380 390 pF1KA1 KSSSLTRTGNTVATDMLSEHPLLSEPSSVSFYNWMSNAVGNRGSVLQESPVTKSGHNSLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KSSSLTRTGNTVATDMLSEHPLLSEPSSVSFYNWMSNAVGNRGSVLQESPVTKSGHNSLP 2280 2290 2300 2310 2320 2330 400 410 420 430 440 450 pF1KA1 TGVAPNLPTIPSASDFNTVLSSDQNTLDGTHSQHSTSQDDVAGVEEANQGFPAVQLADAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TGVAPNLPTIPSASDFNTVLSSDQNTLDGTHSQHSTSQDDVAGVEEANQGFPAVQLADAQ 2340 2350 2360 2370 2380 2390 460 470 480 490 500 510 pF1KA1 VVFKPLLSHTGIQSQDTMPFCYRMYFGEHLSFSGTLDCLRADIVDSDTAKERKGKRARRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVFKPLLSHTGIQSQDTMPFCYRMYFGEHLSFSGTLDCLRADIVDSDTAKERKGKRARRQ 2400 2410 2420 2430 2440 2450 520 530 540 550 560 570 pF1KA1 GHVNLPPLEFKPALMLGTFSISAVVMEKSVCTPQNSTSALSFHDLSKRYYNTFHCNFTIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GHVNLPPLEFKPALMLGTFSISAVVMEKSVCTPQNSTSALSFHDLSKRYYNTFHCNFTIS 2460 2470 2480 2490 2500 2510 580 590 600 610 620 630 pF1KA1 CQSISQHVDMALVRLIHQFSTMIDDIKATQTDIKLSRYTAGSASPTPTFKTRKHRDFRSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CQSISQHVDMALVRLIHQFSTMIDDIKATQTDIKLSRYTAGSASPTPTFKTRKHRDFRSS 2520 2530 2540 2550 2560 2570 640 650 660 670 680 690 pF1KA1 DFSRSSRGSLNGGNRVNNAKNKRTNNENNKKESRNKNSLGRSERRTSKVSRKGSKDVVDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DFSRSSRGSLNGGNRVNNAKNKRTNNENNKKESRNKNSLGRSERRTSKVSRKGSKDVVDH 2580 2590 2600 2610 2620 2630 700 710 720 730 740 750 pF1KA1 MTIHMDDSDSITVSEQSEPSAECWQNMYKLLNFYSLISDPTGILEKSSETFGPAGVRSPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MTIHMDDSDSITVSEQSEPSAECWQNMYKLLNFYSLISDPTGILEKSSETFGPAGVRSPT 2640 2650 2660 2670 2680 2690 760 770 780 790 800 810 pF1KA1 EPTCKVVFENEQDNSSLTKTQRKRSLVTSEPQHVTLIVFGIGMVNRTHLEADIGGLTMES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EPTCKVVFENEQDNSSLTKTQRKRSLVTSEPQHVTLIVFGIGMVNRTHLEADIGGLTMES 2700 2710 2720 2730 2740 2750 820 830 840 850 860 870 pF1KA1 ELKRIHGSFTLKEKMKDVLHQKMTETCATAHIGGVNIVLLEGITPNIQLEDFPTSPTSTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELKRIHGSFTLKEKMKDVLHQKMTETCATAHIGGVNIVLLEGITPNIQLEDFPTSPTSTA 2760 2770 2780 2790 2800 2810 880 890 900 910 920 930 pF1KA1 KQEFLTVVKCSIAKSQALYSAQRGLKTNNAAVFKVGAISINIPQHPATLHSMMVRSSHQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KQEFLTVVKCSIAKSQALYSAQRGLKTNNAAVFKVGAISINIPQHPATLHSMMVRSSHQL 2820 2830 2840 2850 2860 2870 940 950 960 970 980 990 pF1KA1 SKQISDLIRQPSTAPQPVKEDIATPLPSEKTPTSVNQTPVETNEFPQLPEGLEKKPIVLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SKQISDLIRQPSTAPQPVKEDIATPLPSEKTPTSVNQTPVETNEFPQLPEGLEKKPIVLK 2880 2890 2900 2910 2920 2930 1000 1010 1020 1030 1040 1050 pF1KA1 FSAMLDGIAIGAALLPSLKAEYKMGRMRSHGMTGAQTRFTFELPNHRLRFTSKVSATDMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FSAMLDGIAIGAALLPSLKAEYKMGRMRSHGMTGAQTRFTFELPNHRLRFTSKVSATDMS 2940 2950 2960 2970 2980 2990 1060 1070 1080 1090 1100 1110 pF1KA1 TIPPSASLNLPPVTMSGKYIMEEHDSYSDQVWSIDELPSKQGYYLQGNYLRCVAEVGSFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TIPPSASLNLPPVTMSGKYIMEEHDSYSDQVWSIDELPSKQGYYLQGNYLRCVAEVGSFE 3000 3010 3020 3030 3040 3050 1120 1130 1140 1150 1160 1170 pF1KA1 HNLTTDLLNHLVFVQKVFMKEVNEVIQKVSGGEQPIPLWNEHDGTADGDKPKILLYSLNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HNLTTDLLNHLVFVQKVFMKEVNEVIQKVSGGEQPIPLWNEHDGTADGDKPKILLYSLNL 3060 3070 3080 3090 3100 3110 1180 1190 1200 1210 1220 1230 pF1KA1 QFKGIQVTATTPSMRAVRFETGLIELELSNRLQTKASPGSSSYLKLFGKCQVDLNLALGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QFKGIQVTATTPSMRAVRFETGLIELELSNRLQTKASPGSSSYLKLFGKCQVDLNLALGQ 3120 3130 3140 3150 3160 3170 1240 1250 1260 1270 1280 1290 pF1KA1 IVKHQVYEEAGSDFHQVAYFKTRIGLRNALREEISGSSDREAVLITLNRPIVYAQPVAFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IVKHQVYEEAGSDFHQVAYFKTRIGLRNALREEISGSSDREAVLITLNRPIVYAQPVAFD 3180 3190 3200 3210 3220 3230 1300 1310 1320 1330 1340 1350 pF1KA1 RAVLFWLNYKAAYDNWNEQRMALHKDIHMATKEVVDMLPGIQQTSAQAFGTLFLQLTVND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RAVLFWLNYKAAYDNWNEQRMALHKDIHMATKEVVDMLPGIQQTSAQAFGTLFLQLTVND 3240 3250 3260 3270 3280 3290 1360 1370 1380 1390 1400 1410 pF1KA1 LGICLPITNTAQSNHTGDLDTGSALVLTIESTLITACSSESLVSKGHFKNFCIRFADGFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LGICLPITNTAQSNHTGDLDTGSALVLTIESTLITACSSESLVSKGHFKNFCIRFADGFE 3300 3310 3320 3330 3340 3350 1420 1430 1440 1450 1460 1470 pF1KA1 TSWDDWKPEIHGDLVMNACVVPDGTYEVCSRTTGQAAAESSSAGTWTLNVLWKMCGIDVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSWDDWKPEIHGDLVMNACVVPDGTYEVCSRTTGQAAAESSSAGTWTLNVLWKMCGIDVH 3360 3370 3380 3390 3400 3410 1480 1490 1500 1510 1520 pF1KA1 MDPNIGKRLNALGNTLTTLTGEEDIDDIADLNSVNIADLSDEDEVDTMSPTIHT------ :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MDPNIGKRLNALGNTLTTLTGEEDIDDIADLNSVNIADLSDEDEVDTMSPTIHTSSDGSS 3420 3430 3440 3450 3460 3470 pF1KA1 ------------------------------------------------------------ XP_011 ISGDGHKLTFGQRLVNHLLGLTPPNQRHSVPAEYLCDPEMWGSPQSSQSHLKACRAHSWG 3480 3490 3500 3510 3520 3530 1530 1540 1550 1560 1570 1580 pF1KA1 -EATDYRRQAASASQPGELRGRKIMKRIVDIRELNEQAKVIDDLKKLGASEGTINQEIQR ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NEATDYRRQAASASQPGELRGRKIMKRIVDIRELNEQAKVIDDLKKLGASEGTINQEIQR 3540 3550 3560 3570 3580 3590 1590 1600 1610 1620 1630 1640 pF1KA1 YQQLESVAVNDIRRDVRKKLRRSSMRAASLKDKWGLSYKPSYSRSKSISASGRPPLKRME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YQQLESVAVNDIRRDVRKKLRRSSMRAASLKDKWGLSYKPSYSRSKSISASGRPPLKRME 3600 3610 3620 3630 3640 3650 1650 1660 1670 1680 pF1KA1 RASSRVGETEELPEIRVDAASPGPRVTFNIQDT---------------------FPEETE ::::::::::::::::::::::::::::::::: :::::: XP_011 RASSRVGETEELPEIRVDAASPGPRVTFNIQDTLKNTVWGSTPQSSCPGEGYFQFPEETE 3660 3670 3680 3690 3700 3710 1690 1700 1710 1720 1730 1740 pF1KA1 LDLLSVTIEGPSHYSSNSEGSCSVFSSPKTPGGFSPGIPFQTEEGRRDDSLSSTSEDSEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDLLSVTIEGPSHYSSNSEGSCSVFSSPKTPGGFSPGIPFQTEEGRRDDSLSSTSEDSEK 3720 3730 3740 3750 3760 3770 1750 1760 1770 1780 1790 1800 pF1KA1 DEKDEDHERERFYIYRKPSHTSRKKATGFAAVHQLFTERWPTTPVNRSLSGTATERNIDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DEKDEDHERERFYIYRKPSHTSRKKATGFAAVHQLFTERWPTTPVNRSLSGTATERNIDF 3780 3790 3800 3810 3820 3830 1810 1820 1830 1840 1850 1860 pF1KA1 ELDIRVEIDSGKCVLHPTTLLQEHDDISLRRSYDRSSRSLDQDSPSKKKKFQTNYASTTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELDIRVEIDSGKCVLHPTTLLQEHDDISLRRSYDRSSRSLDQDSPSKKKKFQTNYASTTH 3840 3850 3860 3870 3880 3890 1870 1880 1890 1900 1910 1920 pF1KA1 LMTGKKVPSSLQTKPSDLETTVFYIPGVDVKLHYNSKTLKTESPNASRGSSLPRTLSKES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LMTGKKVPSSLQTKPSDLETTVFYIPGVDVKLHYNSKTLKTESPNASRGSSLPRTLSKES 3900 3910 3920 3930 3940 3950 1930 1940 1950 1960 1970 1980 pF1KA1 KLYGMKDSATSPPSPPLPSTVQSKTNTLLPPQPPPIPAAKGKGSGGVKTAKLYAWVALQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLYGMKDSATSPPSPPLPSTVQSKTNTLLPPQPPPIPAAKGKGSGGVKTAKLYAWVALQS 3960 3970 3980 3990 4000 4010 1990 2000 2010 2020 2030 2040 pF1KA1 LPEEMVISPCLLDFLEKALETIPITPVERNYTAVSSQDEDMGHFEIPDPMEESTTSLVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPEEMVISPCLLDFLEKALETIPITPVERNYTAVSSQDEDMGHFEIPDPMEESTTSLVSS 4020 4030 4040 4050 4060 4070 2050 2060 2070 2080 2090 2100 pF1KA1 STSAYSSFPVDVVVYVRVQPSQIKFSCLPVSRVECMLKLPSLDLVFSSNRGELETLGTTY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STSAYSSFPVDVVVYVRVQPSQIKFSCLPVSRVECMLKLPSLDLVFSSNRGELETLGTTY 4080 4090 4100 4110 4120 4130 2110 2120 2130 2140 2150 2160 pF1KA1 PAETLSPGGNATQSGTKTSASKTGIPGSSGLGSPLGRSRHSSSQSDLTSSSSSSSGLSFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PAETLSPGGNATQSGTKTSASKTGIPGSSGLGSPLGRSRHSSSQSDLTSSSSSSSGLSFT 4140 4150 4160 4170 4180 4190 2170 2180 2190 2200 2210 2220 pF1KA1 ACMSDFSLYVFHPYGAGKQKTAVSGLTPGSGGLGNVDEEPTSVTGRKDSLSINLEFVKVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ACMSDFSLYVFHPYGAGKQKTAVSGLTPGSGGLGNVDEEPTSVTGRKDSLSINLEFVKVS 4200 4210 4220 4230 4240 4250 2230 2240 2250 2260 2270 2280 pF1KA1 LSRIRRSGGASFFESQSVSKSASKMDTTLINISAVCDIGSASFKYDMRRLSEILAFPRAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSRIRRSGGASFFESQSVSKSASKMDTTLINISAVCDIGSASFKYDMRRLSEILAFPRAW 4260 4270 4280 4290 4300 4310 2290 2300 2310 2320 2330 2340 pF1KA1 YRRSIARRLFLGDQTINLPTSGPGTPDSIEGVSQHLSPESSRKAYCKTWEQPSQSASFTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YRRSIARRLFLGDQTINLPTSGPGTPDSIEGVSQHLSPESSRKAYCKTWEQPSQSASFTH 4320 4330 4340 4350 4360 4370 2350 2360 2370 2380 2390 2400 pF1KA1 MPQSPNVFNEHMTNSTMSPGTVGQSLKSPASIRSRSVSDSSVPRRDSLSKTSTPFNKSNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MPQSPNVFNEHMTNSTMSPGTVGQSLKSPASIRSRSVSDSSVPRRDSLSKTSTPFNKSNK 4380 4390 4400 4410 4420 4430 2410 2420 2430 2440 2450 2460 pF1KA1 AASQQGTPWETLVVFAINLKQLNVQMNMSNVMGNTTWTTSGLKSQGRLSVGSNRDREISM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AASQQGTPWETLVVFAINLKQLNVQMNMSNVMGNTTWTTSGLKSQGRLSVGSNRDREISM 4440 4450 4460 4470 4480 4490 2470 2480 2490 2500 2510 2520 pF1KA1 SVGLGRSQLDSKGGVVGGTIDVNALEMVAHISEHPNQQPSHKIQITMGSTEARVDYMGSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SVGLGRSQLDSKGGVVGGTIDVNALEMVAHISEHPNQQPSHKIQITMGSTEARVDYMGSS 4500 4510 4520 4530 4540 4550 2530 2540 2550 2560 2570 2580 pF1KA1 ILMGIFSNADLKLQDEWKVNLYNTLDSSITDKSEIFVHGDLKWDIFQVMISRSTTPDLIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILMGIFSNADLKLQDEWKVNLYNTLDSSITDKSEIFVHGDLKWDIFQVMISRSTTPDLIK 4560 4570 4580 4590 4600 4610 2590 2600 2610 2620 2630 2640 pF1KA1 IGMKLQEFFTQQFDTSKRALSTWGPVPYLPPKTMTSNLEKSSQEQLLDAAHHRHWPGVLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IGMKLQEFFTQQFDTSKRALSTWGPVPYLPPKTMTSNLEKSSQEQLLDAAHHRHWPGVLK 4620 4630 4640 4650 4660 4670 2650 2660 2670 2680 2690 2700 pF1KA1 VVSGCHISLFQIPLPEDGMQFGGSMSLHGNHMTLACFHGPNFRSKSWALFHLEEPNIAFW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVSGCHISLFQIPLPEDGMQFGGSMSLHGNHMTLACFHGPNFRSKSWALFHLEEPNIAFW 4680 4690 4700 4710 4720 4730 2710 2720 2730 2740 2750 2760 pF1KA1 TEAQKIWEDGSSDHSTYIVQTLDFHLGHNTMVTKPCGALESPMATITKITRRRHENPPHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TEAQKIWEDGSSDHSTYIVQTLDFHLGHNTMVTKPCGALESPMATITKITRRRHENPPHG 4740 4750 4760 4770 4780 4790 2770 2780 2790 2800 2810 2820 pF1KA1 VASVKEWFNYVTATRNEELNLLRNVDANNTENSTTVKNSSLLSGFRGGSSYNHETETIFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VASVKEWFNYVTATRNEELNLLRNVDANNTENSTTVKNSSLLSGFRGGSSYNHETETIFA 4800 4810 4820 4830 4840 4850 2830 2840 2850 2860 2870 2880 pF1KA1 LPRMQLDFKSIHVQEPQEPSLQDASLKPKVECSVVTEFTDHICVTMDAELIMFLHDLVSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPRMQLDFKSIHVQEPQEPSLQDASLKPKVECSVVTEFTDHICVTMDAELIMFLHDLVSA 4860 4870 4880 4890 4900 4910 2890 2900 2910 2920 2930 2940 pF1KA1 YLKEKEKAIFPPRILSTRPGQKSPIIIHDDNSSDKDREDSITYTTVDWRDFMCNTWHLEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YLKEKEKAIFPPRILSTRPGQKSPIIIHDDNSSDKDREDSITYTTVDWRDFMCNTWHLEP 4920 4930 4940 4950 4960 4970 2950 2960 2970 2980 2990 3000 pF1KA1 TLRLISWTGRKIDPVGVDYILQKLGFHHARTTIPKWLQRGVMDPLDKVLSVLIKKLGTAL :::::::::::::::::: XP_011 TLRLISWTGRKIDPVGVDYILQKLGFHHARTTIPKWLQRGVMDPLDKVLSVLIKKLGTAL 4980 4990 5000 5010 5020 5030 >-- initn: 371 init1: 371 opt: 371 Z-score: 267.2 bits: 64.9 E(85289): 3.8e-08 Smith-Waterman score: 371; 100.0% identity (100.0% similar) in 56 aa overlap (2961-3016:4995-5050) 2940 2950 2960 2970 2980 2990 pF1KA1 RDFMCNTWHLEPTLRLISWTGRKIDPVGVDYILQKLGFHHARTTIPKWLQRGVMDPLDKV :::::::::::::::::::::::::::::: XP_011 RDFMCNTWHLEPTLRLISWTGRKIDPVGVDYILQKLGFHHARTTIPKWLQRGVMDPLDKV 4970 4980 4990 5000 5010 5020 3000 3010 pF1KA1 LSVLIKKLGTALQDEKEKKGKDKEEH :::::::::::::::::::::::::: XP_011 LSVLIKKLGTALQDEKEKKGKDKEEH 5030 5040 5050 3016 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 10:45:18 2016 done: Thu Nov 3 10:45:22 2016 Total Scan time: 27.670 Total Display time: 2.970 Function used was FASTA [36.3.4 Apr, 2011]