FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1121, 1353 aa 1>>>pF1KA1121 1353 - 1353 aa - 1353 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.8764+/-0.000495; mu= 14.1977+/- 0.031 mean_var=290.6568+/-59.519, 0's: 0 Z-trim(117.1): 112 B-trim: 0 in 0/54 Lambda= 0.075229 statistics sampled from 28609 (28721) to 28609 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.658), E-opt: 0.2 (0.337), width: 16 Scan time: 15.840 The best scores are: opt bits E(85289) NP_003707 (OMIM: 604667) calcium-dependent secreti (1353) 8958 987.7 0 XP_011532496 (OMIM: 604667) PREDICTED: calcium-dep (1357) 8930 984.7 0 XP_016862864 (OMIM: 604667) PREDICTED: calcium-dep (1349) 8891 980.5 0 XP_016862866 (OMIM: 604667) PREDICTED: calcium-dep (1346) 8881 979.4 0 XP_016862861 (OMIM: 604667) PREDICTED: calcium-dep (1354) 8871 978.3 0 XP_016862862 (OMIM: 604667) PREDICTED: calcium-dep (1353) 8863 977.4 0 XP_016862863 (OMIM: 604667) PREDICTED: calcium-dep (1350) 8853 976.3 0 XP_011532495 (OMIM: 604667) PREDICTED: calcium-dep (1358) 8843 975.3 0 XP_011532505 (OMIM: 604667) PREDICTED: calcium-dep (1347) 8802 970.8 0 XP_011532498 (OMIM: 604667) PREDICTED: calcium-dep (1352) 8782 968.6 0 XP_016862858 (OMIM: 604667) PREDICTED: calcium-dep (1362) 7720 853.4 0 XP_016862867 (OMIM: 604667) PREDICTED: calcium-dep (1345) 7059 781.6 0 XP_016862865 (OMIM: 604667) PREDICTED: calcium-dep (1348) 6856 759.6 3.4e-218 XP_016862859 (OMIM: 604667) PREDICTED: calcium-dep (1357) 6852 759.2 4.6e-218 XP_016862860 (OMIM: 604667) PREDICTED: calcium-dep (1354) 6846 758.5 7.2e-218 XP_011532497 (OMIM: 604667) PREDICTED: calcium-dep (1353) 6836 757.4 1.5e-217 XP_016862873 (OMIM: 604667) PREDICTED: calcium-dep (1308) 6682 740.7 1.6e-212 XP_011532500 (OMIM: 604667) PREDICTED: calcium-dep (1297) 6633 735.4 6.4e-211 XP_016862874 (OMIM: 604667) PREDICTED: calcium-dep (1304) 6615 733.4 2.5e-210 XP_016862875 (OMIM: 604667) PREDICTED: calcium-dep (1301) 6605 732.3 5.3e-210 XP_011532502 (OMIM: 604667) PREDICTED: calcium-dep (1291) 5904 656.2 4.2e-187 XP_011532501 (OMIM: 604667) PREDICTED: calcium-dep (1296) 5904 656.3 4.2e-187 XP_016862868 (OMIM: 604667) PREDICTED: calcium-dep (1344) 5897 655.5 7.3e-187 XP_006713441 (OMIM: 604667) PREDICTED: calcium-dep (1295) 5876 653.2 3.5e-186 XP_011532493 (OMIM: 604667) PREDICTED: calcium-dep (1363) 5717 636.0 5.6e-181 XP_016862857 (OMIM: 604667) PREDICTED: calcium-dep (1368) 5717 636.0 5.6e-181 NP_899631 (OMIM: 604667) calcium-dependent secreti (1314) 5708 635.0 1.1e-180 XP_016862871 (OMIM: 604667) PREDICTED: calcium-dep (1320) 5708 635.0 1.1e-180 XP_016862856 (OMIM: 604667) PREDICTED: calcium-dep (1369) 5708 635.0 1.1e-180 XP_016862872 (OMIM: 604667) PREDICTED: calcium-dep (1318) 5680 631.9 8.8e-180 XP_016862870 (OMIM: 604667) PREDICTED: calcium-dep (1324) 5680 632.0 8.9e-180 XP_016862869 (OMIM: 604667) PREDICTED: calcium-dep (1325) 5680 632.0 8.9e-180 XP_016862854 (OMIM: 604667) PREDICTED: calcium-dep (1373) 5680 632.0 9.1e-180 XP_011532494 (OMIM: 604667) PREDICTED: calcium-dep (1362) 5642 627.8 1.6e-178 XP_011532499 (OMIM: 604667) PREDICTED: calcium-dep (1344) 5083 567.2 2.9e-160 XP_011532504 (OMIM: 604667) PREDICTED: calcium-dep ( 918) 5055 563.9 1.9e-159 XP_016862855 (OMIM: 604667) PREDICTED: calcium-dep (1371) 5055 564.1 2.4e-159 XP_011532491 (OMIM: 604667) PREDICTED: calcium-dep (1376) 5055 564.1 2.4e-159 XP_016862853 (OMIM: 604667) PREDICTED: calcium-dep (1377) 5055 564.1 2.4e-159 XP_011532485 (OMIM: 604667) PREDICTED: calcium-dep (1402) 5055 564.2 2.4e-159 XP_016862852 (OMIM: 604667) PREDICTED: calcium-dep (1403) 5055 564.2 2.4e-159 XP_016862851 (OMIM: 604667) PREDICTED: calcium-dep (1406) 5055 564.2 2.4e-159 XP_011532484 (OMIM: 604667) PREDICTED: calcium-dep (1408) 5055 564.2 2.4e-159 XP_016862850 (OMIM: 604667) PREDICTED: calcium-dep (1410) 5055 564.2 2.4e-159 XP_011532482 (OMIM: 604667) PREDICTED: calcium-dep (1415) 5055 564.2 2.4e-159 XP_011532480 (OMIM: 604667) PREDICTED: calcium-dep (1425) 5055 564.2 2.4e-159 XP_016862849 (OMIM: 604667) PREDICTED: calcium-dep (1426) 5055 564.2 2.4e-159 XP_016862848 (OMIM: 604667) PREDICTED: calcium-dep (1429) 5055 564.2 2.4e-159 XP_011532479 (OMIM: 604667) PREDICTED: calcium-dep (1431) 5055 564.2 2.4e-159 XP_016862847 (OMIM: 604667) PREDICTED: calcium-dep (1433) 5055 564.2 2.4e-159 >>NP_003707 (OMIM: 604667) calcium-dependent secretion a (1353 aa) initn: 8958 init1: 8958 opt: 8958 Z-score: 5271.2 bits: 987.7 E(85289): 0 Smith-Waterman score: 8958; 99.9% identity (100.0% similar) in 1353 aa overlap (1-1353:1-1353) 10 20 30 40 50 60 pF1KA1 MLDPSSSEEESDEIVEEESGKEVLGSAPSGARLSPSRTSEGSAGSAGLGGGGAGAGAGVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MLDPSSSEEESDEIVEEESGKEVLGSAPSGARLSPSRTSEGSAGSAGLGGGGAGAGAGVG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 AGGGGGSGASSGGGAGGLQPSSRAGGGRPSSPSPSVVSEKEKEELERLQKEEEERKKRLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 AGGGGGSGASSGGGAGGLQPSSRAGGGRPSSPSPSVVSEKEKEELERLQKEEEERKKRLQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 LYVFVMRCIAYPFNAKQPTDMARRQQKISKQQLQTVKDRFQAFLNGETQIMADEAFMNAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 LYVFVMRCIAYPFNAKQPTDMARRQQKISKQQLQTVKDRFQAFLNGETQIMADEAFMNAV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 QSYYEVFLKSDRVARMVQSGGCSANDSREVFKKHIEKRVRSLPEIDGLSKETVLSSWMAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 QSYYEVFLKSDRVARMVQSGGCSANDSREVFKKHIEKRVRSLPEIDGLSKETVLSSWMAK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 FDAIYRGEEDPRKQQARMTASAASELILSKEQLYEMFQNILGIKKFEHQLLYNACQLDNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 FDAIYRGEEDPRKQQARMTASAASELILSKEQLYEMFQNILGIKKFEHQLLYNACQLDNP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 DEQAAQIRRELDGRLQMADQIARERKFPKFVSKEMENMYIEELKSSVNLLMANLESMPVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 DEQAAQIRRELDGRLQMADQIARERKFPKFVSKEMENMYIEELKSSVNLLMANLESMPVS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 KGGEFKLQKLKRSHNASIIDMGEESENQLSKSDVVLSFSLEVVIMEVQGLKSLAPNRIVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 KGGEFKLQKLKRSHNASIIDMGEESENQLSKSDVVLSFSLEVVIMEVQGLKSLAPNRIVY 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 CTMEVEGGEKLQTDQAEASKPTWGTQGDFSTTHALPAVKVKLFTESTGVLALEDKELGRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 CTMEVEGGEKLQTDQAEASKPTWGTQGDFSTTHALPAVKVKLFTESTGVLALEDKELGRV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 ILHPTPNSPKQSEWHKMTVSKNCPDQDLKIKLAVRMDKPQNMKHSGYLWAIGKNVWKRWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 ILHPTPNSPKQSEWHKMTVSKNCPDQDLKIKLAVRMDKPQNMKHSGYLWAIGKNVWKRWK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 KRFFVLVQVSQYTFAMCSYREKKAEPQELLQLDGYTVDYTDPQPGLEGGRAFFNAVKEGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 KRFFVLVQVSQYTFAMCSYREKKAEPQELLQLDGYTVDYTDPQPGLEGGRAFFNAVKEGD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 TVIFASDDEQDRILWVQAMYRATGQSHKPVPPTQVQKLNAKGGNVPQLDAPISQFYADRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 TVIFASDDEQDRILWVQAMYRATGQSHKPVPPTQVQKLNAKGGNVPQLDAPISQFYADRA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 QKHGMDEFISSNPCNFDHASLFEMVQRLTLDHRLNDSYSCLGWFSPGQVFVLDEYCARNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 QKHGMDEFISSNPCNFDHASLFEMVQRLTLDHRLNDSYSCLGWFSPGQVFVLDEYCARNG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 VRGCHRHLCYLRDLLERAENGAMIDPTLLHYSFAFCASHVHGNRPDGIGTVTVEEKERFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 VRGCHRHLCYLRDLLERAENGAMIDPTLLHYSFAFCASHVHGNRPDGIGTVTVEEKERFE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 EIKERLRVLLENQITHFRYCFPFGRPEGALKATLSLLERVLMKDIVTPVPQEEVKTVIRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 EIKERLRVLLENQITHFRYCFPFGRPEGALKATLSLLERVLMKDIVTPVPQEEVKTVIRK 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 CLEQAALVNYSRLSEYAKIEENQKDAENVGRLITPAKKLEDTIRLAELVIEVLQQNEEHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 CLEQAALVNYSRLSEYAKIEENQKDAENVGRLITPAKKLEDTIRLAELVIEVLQQNEEHH 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 AEPHVDKGEAFAWWSDLMVEHAETFLSLFAVDMDAALEVQPPDTWDSFPLFQLLNDFLRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 AEPHVDKGEAFAWWSDLMVEHAETFLSLFAVDMDAALEVQPPDTWDSFPLFQLLNDFLRT 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 DYNLCNGKFHKHLQDLFAPLVVRYVDLMESSIAQSIHRGFERESWEPVKSLTSNLPNVNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 DYNLCNGKFHKHLQDLFAPLVVRYVDLMESSIAQSIHRGFERESWEPVKSLTSNLPNVNL 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA1 PNVNLPKVPNLPVNIPLGIPQMPTFSAPSWMAAIYDADNGSGTSEDLFWKLDALQTFIRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 PNVNLPKVPNLPVNIPLGIPQMPTFSAPSWMAAIYDADNGSGTSEDLFWKLDALQTFIRD 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA1 LHWPEEEFGKHLEQRLKLMASDMIESCVKRTRIAFEVKLQKTSRSTDFRVPQSICTMFNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 LHWPEEEFGKHLEQRLKLMASDMIESCVKRTRIAFEVKLQKTSRSTDFRVPQSICTMFNV 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA1 MVDAKAQSTKLCSMEMGQEHQYHSKIDELIEETVKEMITLLVAKFVTILEGVLAKLSRYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MVDAKAQSTKLCSMEMGQEHQYHSKIDELIEETVKEMITLLVAKFVTILEGVLAKLSRYD 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA1 EGTLFSSFLSFTVKAASKYVDVPKPGMDVADAYVTFVRHSQDVLRDKVNEEMYIERLFDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 EGTLFSSFLSFTVKAASKYVDVPKPGMDVADAYVTFVRHSQDVLRDKVNEEMYIERLFDQ 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA1 WYNSSMNVICTWLTDRMDLQLHIYQLKTLIRVVKKTYRDFRLQGVLDSTLNSKTYETIRN :::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::: NP_003 WYNSSMNVICTWLTDRMDLQLHIYQLKTLIRMVKKTYRDFRLQGVLDSTLNSKTYETIRN 1270 1280 1290 1300 1310 1320 1330 1340 1350 pF1KA1 RLTVEEATASVSEGGGLQGISMKDSDEEDEEDD ::::::::::::::::::::::::::::::::: NP_003 RLTVEEATASVSEGGGLQGISMKDSDEEDEEDD 1330 1340 1350 >>XP_011532496 (OMIM: 604667) PREDICTED: calcium-depende (1357 aa) initn: 8936 init1: 4647 opt: 8930 Z-score: 5254.8 bits: 984.7 E(85289): 0 Smith-Waterman score: 8930; 99.6% identity (99.6% similar) in 1357 aa overlap (1-1353:1-1357) 10 20 30 40 50 60 pF1KA1 MLDPSSSEEESDEIVEEESGKEVLGSAPSGARLSPSRTSEGSAGSAGLGGGGAGAGAGVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MLDPSSSEEESDEIVEEESGKEVLGSAPSGARLSPSRTSEGSAGSAGLGGGGAGAGAGVG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 AGGGGGSGASSGGGAGGLQPSSRAGGGRPSSPSPSVVSEKEKEELERLQKEEEERKKRLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AGGGGGSGASSGGGAGGLQPSSRAGGGRPSSPSPSVVSEKEKEELERLQKEEEERKKRLQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 LYVFVMRCIAYPFNAKQPTDMARRQQKISKQQLQTVKDRFQAFLNGETQIMADEAFMNAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LYVFVMRCIAYPFNAKQPTDMARRQQKISKQQLQTVKDRFQAFLNGETQIMADEAFMNAV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 QSYYEVFLKSDRVARMVQSGGCSANDSREVFKKHIEKRVRSLPEIDGLSKETVLSSWMAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSYYEVFLKSDRVARMVQSGGCSANDSREVFKKHIEKRVRSLPEIDGLSKETVLSSWMAK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 FDAIYRGEEDPRKQQARMTASAASELILSKEQLYEMFQNILGIKKFEHQLLYNACQLDNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FDAIYRGEEDPRKQQARMTASAASELILSKEQLYEMFQNILGIKKFEHQLLYNACQLDNP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 DEQAAQIRRELDGRLQMADQIARERKFPKFVSKEMENMYIEELKSSVNLLMANLESMPVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DEQAAQIRRELDGRLQMADQIARERKFPKFVSKEMENMYIEELKSSVNLLMANLESMPVS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 KGGEFKLQKLKRSHNASIIDMGEESENQLSKSDVVLSFSLEVVIMEVQGLKSLAPNRIVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KGGEFKLQKLKRSHNASIIDMGEESENQLSKSDVVLSFSLEVVIMEVQGLKSLAPNRIVY 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 CTMEVEGGEKLQTDQAEASKPTWGTQGDFSTTHALPAVKVKLFTESTGVLALEDKELGRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CTMEVEGGEKLQTDQAEASKPTWGTQGDFSTTHALPAVKVKLFTESTGVLALEDKELGRV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 ILHPTPNSPKQSEWHKMTVSKNCPDQDLKIKLAVRMDKPQNMKHSGYLWAIGKNVWKRWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILHPTPNSPKQSEWHKMTVSKNCPDQDLKIKLAVRMDKPQNMKHSGYLWAIGKNVWKRWK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 KRFFVLVQVSQYTFAMCSYREKKAEPQELLQLDGYTVDYTDPQPGLEGGRAFFNAVKEGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KRFFVLVQVSQYTFAMCSYREKKAEPQELLQLDGYTVDYTDPQPGLEGGRAFFNAVKEGD 550 560 570 580 590 600 610 620 630 640 650 pF1KA1 TVIFASDDEQDRILWVQAMYRATGQSHKPVPPTQVQKLNAKGGNVPQLDAPISQFY---- ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TVIFASDDEQDRILWVQAMYRATGQSHKPVPPTQVQKLNAKGGNVPQLDAPISQFSGLKD 610 620 630 640 650 660 660 670 680 690 700 710 pF1KA1 ADRAQKHGMDEFISSNPCNFDHASLFEMVQRLTLDHRLNDSYSCLGWFSPGQVFVLDEYC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ADRAQKHGMDEFISSNPCNFDHASLFEMVQRLTLDHRLNDSYSCLGWFSPGQVFVLDEYC 670 680 690 700 710 720 720 730 740 750 760 770 pF1KA1 ARNGVRGCHRHLCYLRDLLERAENGAMIDPTLLHYSFAFCASHVHGNRPDGIGTVTVEEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ARNGVRGCHRHLCYLRDLLERAENGAMIDPTLLHYSFAFCASHVHGNRPDGIGTVTVEEK 730 740 750 760 770 780 780 790 800 810 820 830 pF1KA1 ERFEEIKERLRVLLENQITHFRYCFPFGRPEGALKATLSLLERVLMKDIVTPVPQEEVKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ERFEEIKERLRVLLENQITHFRYCFPFGRPEGALKATLSLLERVLMKDIVTPVPQEEVKT 790 800 810 820 830 840 840 850 860 870 880 890 pF1KA1 VIRKCLEQAALVNYSRLSEYAKIEENQKDAENVGRLITPAKKLEDTIRLAELVIEVLQQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VIRKCLEQAALVNYSRLSEYAKIEENQKDAENVGRLITPAKKLEDTIRLAELVIEVLQQN 850 860 870 880 890 900 900 910 920 930 940 950 pF1KA1 EEHHAEPHVDKGEAFAWWSDLMVEHAETFLSLFAVDMDAALEVQPPDTWDSFPLFQLLND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEHHAEPHVDKGEAFAWWSDLMVEHAETFLSLFAVDMDAALEVQPPDTWDSFPLFQLLND 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KA1 FLRTDYNLCNGKFHKHLQDLFAPLVVRYVDLMESSIAQSIHRGFERESWEPVKSLTSNLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FLRTDYNLCNGKFHKHLQDLFAPLVVRYVDLMESSIAQSIHRGFERESWEPVKSLTSNLP 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KA1 NVNLPNVNLPKVPNLPVNIPLGIPQMPTFSAPSWMAAIYDADNGSGTSEDLFWKLDALQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NVNLPNVNLPKVPNLPVNIPLGIPQMPTFSAPSWMAAIYDADNGSGTSEDLFWKLDALQT 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 1130 pF1KA1 FIRDLHWPEEEFGKHLEQRLKLMASDMIESCVKRTRIAFEVKLQKTSRSTDFRVPQSICT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FIRDLHWPEEEFGKHLEQRLKLMASDMIESCVKRTRIAFEVKLQKTSRSTDFRVPQSICT 1090 1100 1110 1120 1130 1140 1140 1150 1160 1170 1180 1190 pF1KA1 MFNVMVDAKAQSTKLCSMEMGQEHQYHSKIDELIEETVKEMITLLVAKFVTILEGVLAKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MFNVMVDAKAQSTKLCSMEMGQEHQYHSKIDELIEETVKEMITLLVAKFVTILEGVLAKL 1150 1160 1170 1180 1190 1200 1200 1210 1220 1230 1240 1250 pF1KA1 SRYDEGTLFSSFLSFTVKAASKYVDVPKPGMDVADAYVTFVRHSQDVLRDKVNEEMYIER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRYDEGTLFSSFLSFTVKAASKYVDVPKPGMDVADAYVTFVRHSQDVLRDKVNEEMYIER 1210 1220 1230 1240 1250 1260 1260 1270 1280 1290 1300 1310 pF1KA1 LFDQWYNSSMNVICTWLTDRMDLQLHIYQLKTLIRVVKKTYRDFRLQGVLDSTLNSKTYE :::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::: XP_011 LFDQWYNSSMNVICTWLTDRMDLQLHIYQLKTLIRMVKKTYRDFRLQGVLDSTLNSKTYE 1270 1280 1290 1300 1310 1320 1320 1330 1340 1350 pF1KA1 TIRNRLTVEEATASVSEGGGLQGISMKDSDEEDEEDD ::::::::::::::::::::::::::::::::::::: XP_011 TIRNRLTVEEATASVSEGGGLQGISMKDSDEEDEEDD 1330 1340 1350 >>XP_016862864 (OMIM: 604667) PREDICTED: calcium-depende (1349 aa) initn: 5965 init1: 5965 opt: 8891 Z-score: 5231.9 bits: 980.5 E(85289): 0 Smith-Waterman score: 8891; 99.5% identity (99.6% similar) in 1353 aa overlap (1-1353:1-1349) 10 20 30 40 50 60 pF1KA1 MLDPSSSEEESDEIVEEESGKEVLGSAPSGARLSPSRTSEGSAGSAGLGGGGAGAGAGVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLDPSSSEEESDEIVEEESGKEVLGSAPSGARLSPSRTSEGSAGSAGLGGGGAGAGAGVG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 AGGGGGSGASSGGGAGGLQPSSRAGGGRPSSPSPSVVSEKEKEELERLQKEEEERKKRLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGGGGGSGASSGGGAGGLQPSSRAGGGRPSSPSPSVVSEKEKEELERLQKEEEERKKRLQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 LYVFVMRCIAYPFNAKQPTDMARRQQKISKQQLQTVKDRFQAFLNGETQIMADEAFMNAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LYVFVMRCIAYPFNAKQPTDMARRQQKISKQQLQTVKDRFQAFLNGETQIMADEAFMNAV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 QSYYEVFLKSDRVARMVQSGGCSANDSREVFKKHIEKRVRSLPEIDGLSKETVLSSWMAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSYYEVFLKSDRVARMVQSGGCSANDSREVFKKHIEKRVRSLPEIDGLSKETVLSSWMAK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 FDAIYRGEEDPRKQQARMTASAASELILSKEQLYEMFQNILGIKKFEHQLLYNACQLDNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FDAIYRGEEDPRKQQARMTASAASELILSKEQLYEMFQNILGIKKFEHQLLYNACQLDNP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 DEQAAQIRRELDGRLQMADQIARERKFPKFVSKEMENMYIEELKSSVNLLMANLESMPVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DEQAAQIRRELDGRLQMADQIARERKFPKFVSKEMENMYIEELKSSVNLLMANLESMPVS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 KGGEFKLQKLKRSHNASIIDMGEESENQLSKSDVVLSFSLEVVIMEVQGLKSLAPNRIVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KGGEFKLQKLKRSHNASIIDMGEESENQLSKSDVVLSFSLEVVIMEVQGLKSLAPNRIVY 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 CTMEVEGGEKLQTDQAEASKPTWGTQGDFSTTHALPAVKVKLFTESTGVLALEDKELGRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CTMEVEGGEKLQTDQAEASKPTWGTQGDFSTTHALPAVKVKLFTESTGVLALEDKELGRV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 ILHPTPNSPKQSEWHKMTVSKNCPDQDLKIKLAVRMDKPQNMKHSGYLWAIGKNVWKRWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILHPTPNSPKQSEWHKMTVSKNCPDQDLKIKLAVRMDKPQNMKHSGYLWAIGKNVWKRWK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 KRFFVLVQVSQYTFAMCSYREKKAEPQELLQLDGYTVDYTDPQPGLEGGRAFFNAVKEGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KRFFVLVQVSQYTFAMCSYREKKAEPQELLQLDGYTVDYTDPQPGLEGGRAFFNAVKEGD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 TVIFASDDEQDRILWVQAMYRATGQSHKPVPPTQVQKLNAKGGNVPQLDAPISQFYADRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TVIFASDDEQDRILWVQAMYRATGQSHKPVPPTQVQKLNAKGGNVPQLDAPISQFYADRA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 QKHGMDEFISSNPCNFDHASLFEMVQRLTLDHRLNDSYSCLGWFSPGQVFVLDEYCARNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QKHGMDEFISSNPCNFDHASLFEMVQRLTLDHRLNDSYSCLGWFSPGQVFVLDEYCARNG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 VRGCHRHLCYLRDLLERAENGAMIDPTLLHYSFAFCASHVHGNRPDGIGTVTVEEKERFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VRGCHRHLCYLRDLLERAENGAMIDPTLLHYSFAFCASHVHGNRPDGIGTVTVEEKERFE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 EIKERLRVLLENQITHFRYCFPFGRPEGALKATLSLLERVLMKDIVTPVPQEEVKTVIRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EIKERLRVLLENQITHFRYCFPFGRPEGALKATLSLLERVLMKDIVTPVPQEEVKTVIRK 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 CLEQAALVNYSRLSEYAKIEENQKDAENVGRLITPAKKLEDTIRLAELVIEVLQQNEEHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CLEQAALVNYSRLSEYAKIEENQKDAENVGRLITPAKKLEDTIRLAELVIEVLQQNEEHH 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 AEPHVDKGEAFAWWSDLMVEHAETFLSLFAVDMDAALEVQPPDTWDSFPLFQLLNDFLRT :: . :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AEGK----EAFAWWSDLMVEHAETFLSLFAVDMDAALEVQPPDTWDSFPLFQLLNDFLRT 910 920 930 940 950 970 980 990 1000 1010 1020 pF1KA1 DYNLCNGKFHKHLQDLFAPLVVRYVDLMESSIAQSIHRGFERESWEPVKSLTSNLPNVNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DYNLCNGKFHKHLQDLFAPLVVRYVDLMESSIAQSIHRGFERESWEPVKSLTSNLPNVNL 960 970 980 990 1000 1010 1030 1040 1050 1060 1070 1080 pF1KA1 PNVNLPKVPNLPVNIPLGIPQMPTFSAPSWMAAIYDADNGSGTSEDLFWKLDALQTFIRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PNVNLPKVPNLPVNIPLGIPQMPTFSAPSWMAAIYDADNGSGTSEDLFWKLDALQTFIRD 1020 1030 1040 1050 1060 1070 1090 1100 1110 1120 1130 1140 pF1KA1 LHWPEEEFGKHLEQRLKLMASDMIESCVKRTRIAFEVKLQKTSRSTDFRVPQSICTMFNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHWPEEEFGKHLEQRLKLMASDMIESCVKRTRIAFEVKLQKTSRSTDFRVPQSICTMFNV 1080 1090 1100 1110 1120 1130 1150 1160 1170 1180 1190 1200 pF1KA1 MVDAKAQSTKLCSMEMGQEHQYHSKIDELIEETVKEMITLLVAKFVTILEGVLAKLSRYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MVDAKAQSTKLCSMEMGQEHQYHSKIDELIEETVKEMITLLVAKFVTILEGVLAKLSRYD 1140 1150 1160 1170 1180 1190 1210 1220 1230 1240 1250 1260 pF1KA1 EGTLFSSFLSFTVKAASKYVDVPKPGMDVADAYVTFVRHSQDVLRDKVNEEMYIERLFDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGTLFSSFLSFTVKAASKYVDVPKPGMDVADAYVTFVRHSQDVLRDKVNEEMYIERLFDQ 1200 1210 1220 1230 1240 1250 1270 1280 1290 1300 1310 1320 pF1KA1 WYNSSMNVICTWLTDRMDLQLHIYQLKTLIRVVKKTYRDFRLQGVLDSTLNSKTYETIRN :::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::: XP_016 WYNSSMNVICTWLTDRMDLQLHIYQLKTLIRMVKKTYRDFRLQGVLDSTLNSKTYETIRN 1260 1270 1280 1290 1300 1310 1330 1340 1350 pF1KA1 RLTVEEATASVSEGGGLQGISMKDSDEEDEEDD ::::::::::::::::::::::::::::::::: XP_016 RLTVEEATASVSEGGGLQGISMKDSDEEDEEDD 1320 1330 1340 >>XP_016862866 (OMIM: 604667) PREDICTED: calcium-depende (1346 aa) initn: 5965 init1: 5965 opt: 8881 Z-score: 5226.1 bits: 979.4 E(85289): 0 Smith-Waterman score: 8881; 99.4% identity (99.5% similar) in 1353 aa overlap (1-1353:1-1346) 10 20 30 40 50 60 pF1KA1 MLDPSSSEEESDEIVEEESGKEVLGSAPSGARLSPSRTSEGSAGSAGLGGGGAGAGAGVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLDPSSSEEESDEIVEEESGKEVLGSAPSGARLSPSRTSEGSAGSAGLGGGGAGAGAGVG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 AGGGGGSGASSGGGAGGLQPSSRAGGGRPSSPSPSVVSEKEKEELERLQKEEEERKKRLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGGGGGSGASSGGGAGGLQPSSRAGGGRPSSPSPSVVSEKEKEELERLQKEEEERKKRLQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 LYVFVMRCIAYPFNAKQPTDMARRQQKISKQQLQTVKDRFQAFLNGETQIMADEAFMNAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LYVFVMRCIAYPFNAKQPTDMARRQQKISKQQLQTVKDRFQAFLNGETQIMADEAFMNAV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 QSYYEVFLKSDRVARMVQSGGCSANDSREVFKKHIEKRVRSLPEIDGLSKETVLSSWMAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSYYEVFLKSDRVARMVQSGGCSANDSREVFKKHIEKRVRSLPEIDGLSKETVLSSWMAK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 FDAIYRGEEDPRKQQARMTASAASELILSKEQLYEMFQNILGIKKFEHQLLYNACQLDNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FDAIYRGEEDPRKQQARMTASAASELILSKEQLYEMFQNILGIKKFEHQLLYNACQLDNP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 DEQAAQIRRELDGRLQMADQIARERKFPKFVSKEMENMYIEELKSSVNLLMANLESMPVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DEQAAQIRRELDGRLQMADQIARERKFPKFVSKEMENMYIEELKSSVNLLMANLESMPVS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 KGGEFKLQKLKRSHNASIIDMGEESENQLSKSDVVLSFSLEVVIMEVQGLKSLAPNRIVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KGGEFKLQKLKRSHNASIIDMGEESENQLSKSDVVLSFSLEVVIMEVQGLKSLAPNRIVY 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 CTMEVEGGEKLQTDQAEASKPTWGTQGDFSTTHALPAVKVKLFTESTGVLALEDKELGRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CTMEVEGGEKLQTDQAEASKPTWGTQGDFSTTHALPAVKVKLFTESTGVLALEDKELGRV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 ILHPTPNSPKQSEWHKMTVSKNCPDQDLKIKLAVRMDKPQNMKHSGYLWAIGKNVWKRWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILHPTPNSPKQSEWHKMTVSKNCPDQDLKIKLAVRMDKPQNMKHSGYLWAIGKNVWKRWK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 KRFFVLVQVSQYTFAMCSYREKKAEPQELLQLDGYTVDYTDPQPGLEGGRAFFNAVKEGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KRFFVLVQVSQYTFAMCSYREKKAEPQELLQLDGYTVDYTDPQPGLEGGRAFFNAVKEGD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 TVIFASDDEQDRILWVQAMYRATGQSHKPVPPTQVQKLNAKGGNVPQLDAPISQFYADRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TVIFASDDEQDRILWVQAMYRATGQSHKPVPPTQVQKLNAKGGNVPQLDAPISQFYADRA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 QKHGMDEFISSNPCNFDHASLFEMVQRLTLDHRLNDSYSCLGWFSPGQVFVLDEYCARNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QKHGMDEFISSNPCNFDHASLFEMVQRLTLDHRLNDSYSCLGWFSPGQVFVLDEYCARNG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 VRGCHRHLCYLRDLLERAENGAMIDPTLLHYSFAFCASHVHGNRPDGIGTVTVEEKERFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VRGCHRHLCYLRDLLERAENGAMIDPTLLHYSFAFCASHVHGNRPDGIGTVTVEEKERFE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 EIKERLRVLLENQITHFRYCFPFGRPEGALKATLSLLERVLMKDIVTPVPQEEVKTVIRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EIKERLRVLLENQITHFRYCFPFGRPEGALKATLSLLERVLMKDIVTPVPQEEVKTVIRK 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 CLEQAALVNYSRLSEYAKIEENQKDAENVGRLITPAKKLEDTIRLAELVIEVLQQNEEHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CLEQAALVNYSRLSEYAKIEENQKDAENVGRLITPAKKLEDTIRLAELVIEVLQQNEEHH 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 AEPHVDKGEAFAWWSDLMVEHAETFLSLFAVDMDAALEVQPPDTWDSFPLFQLLNDFLRT : :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 A-------EAFAWWSDLMVEHAETFLSLFAVDMDAALEVQPPDTWDSFPLFQLLNDFLRT 910 920 930 940 950 970 980 990 1000 1010 1020 pF1KA1 DYNLCNGKFHKHLQDLFAPLVVRYVDLMESSIAQSIHRGFERESWEPVKSLTSNLPNVNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DYNLCNGKFHKHLQDLFAPLVVRYVDLMESSIAQSIHRGFERESWEPVKSLTSNLPNVNL 960 970 980 990 1000 1010 1030 1040 1050 1060 1070 1080 pF1KA1 PNVNLPKVPNLPVNIPLGIPQMPTFSAPSWMAAIYDADNGSGTSEDLFWKLDALQTFIRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PNVNLPKVPNLPVNIPLGIPQMPTFSAPSWMAAIYDADNGSGTSEDLFWKLDALQTFIRD 1020 1030 1040 1050 1060 1070 1090 1100 1110 1120 1130 1140 pF1KA1 LHWPEEEFGKHLEQRLKLMASDMIESCVKRTRIAFEVKLQKTSRSTDFRVPQSICTMFNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHWPEEEFGKHLEQRLKLMASDMIESCVKRTRIAFEVKLQKTSRSTDFRVPQSICTMFNV 1080 1090 1100 1110 1120 1130 1150 1160 1170 1180 1190 1200 pF1KA1 MVDAKAQSTKLCSMEMGQEHQYHSKIDELIEETVKEMITLLVAKFVTILEGVLAKLSRYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MVDAKAQSTKLCSMEMGQEHQYHSKIDELIEETVKEMITLLVAKFVTILEGVLAKLSRYD 1140 1150 1160 1170 1180 1190 1210 1220 1230 1240 1250 1260 pF1KA1 EGTLFSSFLSFTVKAASKYVDVPKPGMDVADAYVTFVRHSQDVLRDKVNEEMYIERLFDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGTLFSSFLSFTVKAASKYVDVPKPGMDVADAYVTFVRHSQDVLRDKVNEEMYIERLFDQ 1200 1210 1220 1230 1240 1250 1270 1280 1290 1300 1310 1320 pF1KA1 WYNSSMNVICTWLTDRMDLQLHIYQLKTLIRVVKKTYRDFRLQGVLDSTLNSKTYETIRN :::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::: XP_016 WYNSSMNVICTWLTDRMDLQLHIYQLKTLIRMVKKTYRDFRLQGVLDSTLNSKTYETIRN 1260 1270 1280 1290 1300 1310 1330 1340 1350 pF1KA1 RLTVEEATASVSEGGGLQGISMKDSDEEDEEDD ::::::::::::::::::::::::::::::::: XP_016 RLTVEEATASVSEGGGLQGISMKDSDEEDEEDD 1320 1330 1340 >>XP_016862861 (OMIM: 604667) PREDICTED: calcium-depende (1354 aa) initn: 7184 init1: 5965 opt: 8871 Z-score: 5220.2 bits: 978.3 E(85289): 0 Smith-Waterman score: 8871; 99.1% identity (99.3% similar) in 1358 aa overlap (1-1353:1-1354) 10 20 30 40 50 60 pF1KA1 MLDPSSSEEESDEIVEEESGKEVLGSAPSGARLSPSRTSEGSAGSAGLGGGGAGAGAGVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLDPSSSEEESDEIVEEESGKEVLGSAPSGARLSPSRTSEGSAGSAGLGGGGAGAGAGVG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 AGGGGGSGASSGGGAGGLQPSSRAGGGRPSSPSPSVVSEKEKEELERLQKEEEERKKRLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGGGGGSGASSGGGAGGLQPSSRAGGGRPSSPSPSVVSEKEKEELERLQKEEEERKKRLQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 LYVFVMRCIAYPFNAKQPTDMARRQQKISKQQLQTVKDRFQAFLNGETQIMADEAFMNAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LYVFVMRCIAYPFNAKQPTDMARRQQKISKQQLQTVKDRFQAFLNGETQIMADEAFMNAV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 QSYYEVFLKSDRVARMVQSGGCSANDSREVFKKHIEKRVRSLPEIDGLSKETVLSSWMAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSYYEVFLKSDRVARMVQSGGCSANDSREVFKKHIEKRVRSLPEIDGLSKETVLSSWMAK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 FDAIYRGEEDPRKQQARMTASAASELILSKEQLYEMFQNILGIKKFEHQLLYNACQLDNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FDAIYRGEEDPRKQQARMTASAASELILSKEQLYEMFQNILGIKKFEHQLLYNACQLDNP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 DEQAAQIRRELDGRLQMADQIARERKFPKFVSKEMENMYIEELKSSVNLLMANLESMPVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DEQAAQIRRELDGRLQMADQIARERKFPKFVSKEMENMYIEELKSSVNLLMANLESMPVS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 KGGEFKLQKLKRSHNASIIDMGEESENQLSKSDVVLSFSLEVVIMEVQGLKSLAPNRIVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KGGEFKLQKLKRSHNASIIDMGEESENQLSKSDVVLSFSLEVVIMEVQGLKSLAPNRIVY 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 CTMEVEGGEKLQTDQAEASKPTWGTQGDFSTTHALPAVKVKLFTESTGVLALEDKELGRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CTMEVEGGEKLQTDQAEASKPTWGTQGDFSTTHALPAVKVKLFTESTGVLALEDKELGRV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 ILHPTPNSPKQSEWHKMTVSKNCPDQDLKIKLAVRMDKPQNMKHSGYLWAIGKNVWKRWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILHPTPNSPKQSEWHKMTVSKNCPDQDLKIKLAVRMDKPQNMKHSGYLWAIGKNVWKRWK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 KRFFVLVQVSQYTFAMCSYREKKAEPQELLQLDGYTVDYTDPQPGLEGGRAFFNAVKEGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KRFFVLVQVSQYTFAMCSYREKKAEPQELLQLDGYTVDYTDPQPGLEGGRAFFNAVKEGD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 TVIFASDDEQDRILWVQAMYRATGQSHKPVPPTQVQKLNAKGGNVPQLDAPISQFYADRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TVIFASDDEQDRILWVQAMYRATGQSHKPVPPTQVQKLNAKGGNVPQLDAPISQFYADRA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 QKHGMDEFISSNPCNFDHASLFEMVQRLTLDHRLNDSYSCLGWFSPGQVFVLDEYCARNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QKHGMDEFISSNPCNFDHASLFEMVQRLTLDHRLNDSYSCLGWFSPGQVFVLDEYCARNG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 VRGCHRHLCYLRDLLERAENGAMIDPTLLHYSFAFCASHVHGNRPDGIGTVTVEEKERFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VRGCHRHLCYLRDLLERAENGAMIDPTLLHYSFAFCASHVHGNRPDGIGTVTVEEKERFE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 EIKERLRVLLENQITHFRYCFPFGRPEGALKATLSLLERVLMKDIVTPVPQEEVKTVIRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EIKERLRVLLENQITHFRYCFPFGRPEGALKATLSLLERVLMKDIVTPVPQEEVKTVIRK 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 CLEQAALVNYSRLSEYAKIEENQKDAENVGRLITPAKKLEDTIRLAELVIEVLQQNEEHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CLEQAALVNYSRLSEYAKIEENQKDAENVGRLITPAKKLEDTIRLAELVIEVLQQNEEHH 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 AEPHVDKGEAFAWWSDLMVEHAETFLSLFAVDMDAALEVQPPDTWDSFPLFQLLNDFLRT :: . :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AEGK----EAFAWWSDLMVEHAETFLSLFAVDMDAALEVQPPDTWDSFPLFQLLNDFLRT 910 920 930 940 950 970 980 990 1000 1010 1020 pF1KA1 DYNLCNGKFHKHLQDLFAPLVVRYVDLMESSIAQSIHRGFERESWEPVKSLTSNLPNVNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DYNLCNGKFHKHLQDLFAPLVVRYVDLMESSIAQSIHRGFERESWEPVKSLTSNLPNVNL 960 970 980 990 1000 1010 1030 1040 1050 1060 1070 1080 pF1KA1 PNVNLPKVPNLPVNIPLGIPQMPTFSAPSWMAAIYDADNGSGTSEDLFWKLDALQTFIRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PNVNLPKVPNLPVNIPLGIPQMPTFSAPSWMAAIYDADNGSGTSEDLFWKLDALQTFIRD 1020 1030 1040 1050 1060 1070 1090 1100 1110 1120 1130 1140 pF1KA1 LHWPEEEFGKHLEQRLKLMASDMIESCVKRTRIAFEVKLQKTSRSTDFRVPQSICTMFNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHWPEEEFGKHLEQRLKLMASDMIESCVKRTRIAFEVKLQKTSRSTDFRVPQSICTMFNV 1080 1090 1100 1110 1120 1130 1150 1160 1170 1180 1190 pF1KA1 MVDAKAQSTKLCSMEMGQE-----HQYHSKIDELIEETVKEMITLLVAKFVTILEGVLAK ::::::::::::::::::: :::::::::::::::::::::::::::::::::::: XP_016 MVDAKAQSTKLCSMEMGQEFAKMWHQYHSKIDELIEETVKEMITLLVAKFVTILEGVLAK 1140 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 pF1KA1 LSRYDEGTLFSSFLSFTVKAASKYVDVPKPGMDVADAYVTFVRHSQDVLRDKVNEEMYIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSRYDEGTLFSSFLSFTVKAASKYVDVPKPGMDVADAYVTFVRHSQDVLRDKVNEEMYIE 1200 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 pF1KA1 RLFDQWYNSSMNVICTWLTDRMDLQLHIYQLKTLIRVVKKTYRDFRLQGVLDSTLNSKTY ::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::: XP_016 RLFDQWYNSSMNVICTWLTDRMDLQLHIYQLKTLIRMVKKTYRDFRLQGVLDSTLNSKTY 1260 1270 1280 1290 1300 1310 1320 1330 1340 1350 pF1KA1 ETIRNRLTVEEATASVSEGGGLQGISMKDSDEEDEEDD :::::::::::::::::::::::::::::::::::::: XP_016 ETIRNRLTVEEATASVSEGGGLQGISMKDSDEEDEEDD 1320 1330 1340 1350 >>XP_016862862 (OMIM: 604667) PREDICTED: calcium-depende (1353 aa) initn: 7045 init1: 7045 opt: 8863 Z-score: 5215.5 bits: 977.4 E(85289): 0 Smith-Waterman score: 8863; 99.1% identity (99.3% similar) in 1357 aa overlap (1-1353:1-1353) 10 20 30 40 50 60 pF1KA1 MLDPSSSEEESDEIVEEESGKEVLGSAPSGARLSPSRTSEGSAGSAGLGGGGAGAGAGVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLDPSSSEEESDEIVEEESGKEVLGSAPSGARLSPSRTSEGSAGSAGLGGGGAGAGAGVG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 AGGGGGSGASSGGGAGGLQPSSRAGGGRPSSPSPSVVSEKEKEELERLQKEEEERKKRLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGGGGGSGASSGGGAGGLQPSSRAGGGRPSSPSPSVVSEKEKEELERLQKEEEERKKRLQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 LYVFVMRCIAYPFNAKQPTDMARRQQKISKQQLQTVKDRFQAFLNGETQIMADEAFMNAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LYVFVMRCIAYPFNAKQPTDMARRQQKISKQQLQTVKDRFQAFLNGETQIMADEAFMNAV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 QSYYEVFLKSDRVARMVQSGGCSANDSREVFKKHIEKRVRSLPEIDGLSKETVLSSWMAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSYYEVFLKSDRVARMVQSGGCSANDSREVFKKHIEKRVRSLPEIDGLSKETVLSSWMAK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 FDAIYRGEEDPRKQQARMTASAASELILSKEQLYEMFQNILGIKKFEHQLLYNACQLDNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FDAIYRGEEDPRKQQARMTASAASELILSKEQLYEMFQNILGIKKFEHQLLYNACQLDNP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 DEQAAQIRRELDGRLQMADQIARERKFPKFVSKEMENMYIEELKSSVNLLMANLESMPVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DEQAAQIRRELDGRLQMADQIARERKFPKFVSKEMENMYIEELKSSVNLLMANLESMPVS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 KGGEFKLQKLKRSHNASIIDMGEESENQLSKSDVVLSFSLEVVIMEVQGLKSLAPNRIVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KGGEFKLQKLKRSHNASIIDMGEESENQLSKSDVVLSFSLEVVIMEVQGLKSLAPNRIVY 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 CTMEVEGGEKLQTDQAEASKPTWGTQGDFSTTHALPAVKVKLFTESTGVLALEDKELGRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CTMEVEGGEKLQTDQAEASKPTWGTQGDFSTTHALPAVKVKLFTESTGVLALEDKELGRV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 ILHPTPNSPKQSEWHKMTVSKNCPDQDLKIKLAVRMDKPQNMKHSGYLWAIGKNVWKRWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILHPTPNSPKQSEWHKMTVSKNCPDQDLKIKLAVRMDKPQNMKHSGYLWAIGKNVWKRWK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 KRFFVLVQVSQYTFAMCSYREKKAEPQELLQLDGYTVDYTDPQPGLEGGRAFFNAVKEGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KRFFVLVQVSQYTFAMCSYREKKAEPQELLQLDGYTVDYTDPQPGLEGGRAFFNAVKEGD 550 560 570 580 590 600 610 620 630 640 650 pF1KA1 TVIFASDDEQDRILWVQAMYRATGQSHKPVPPTQVQKLNAKGGNVPQLDAPISQFY---- ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TVIFASDDEQDRILWVQAMYRATGQSHKPVPPTQVQKLNAKGGNVPQLDAPISQFSGLKD 610 620 630 640 650 660 660 670 680 690 700 710 pF1KA1 ADRAQKHGMDEFISSNPCNFDHASLFEMVQRLTLDHRLNDSYSCLGWFSPGQVFVLDEYC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ADRAQKHGMDEFISSNPCNFDHASLFEMVQRLTLDHRLNDSYSCLGWFSPGQVFVLDEYC 670 680 690 700 710 720 720 730 740 750 760 770 pF1KA1 ARNGVRGCHRHLCYLRDLLERAENGAMIDPTLLHYSFAFCASHVHGNRPDGIGTVTVEEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ARNGVRGCHRHLCYLRDLLERAENGAMIDPTLLHYSFAFCASHVHGNRPDGIGTVTVEEK 730 740 750 760 770 780 780 790 800 810 820 830 pF1KA1 ERFEEIKERLRVLLENQITHFRYCFPFGRPEGALKATLSLLERVLMKDIVTPVPQEEVKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ERFEEIKERLRVLLENQITHFRYCFPFGRPEGALKATLSLLERVLMKDIVTPVPQEEVKT 790 800 810 820 830 840 840 850 860 870 880 890 pF1KA1 VIRKCLEQAALVNYSRLSEYAKIEENQKDAENVGRLITPAKKLEDTIRLAELVIEVLQQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VIRKCLEQAALVNYSRLSEYAKIEENQKDAENVGRLITPAKKLEDTIRLAELVIEVLQQN 850 860 870 880 890 900 900 910 920 930 940 950 pF1KA1 EEHHAEPHVDKGEAFAWWSDLMVEHAETFLSLFAVDMDAALEVQPPDTWDSFPLFQLLND :::::: . :::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEHHAEGK----EAFAWWSDLMVEHAETFLSLFAVDMDAALEVQPPDTWDSFPLFQLLND 910 920 930 940 950 960 970 980 990 1000 1010 pF1KA1 FLRTDYNLCNGKFHKHLQDLFAPLVVRYVDLMESSIAQSIHRGFERESWEPVKSLTSNLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FLRTDYNLCNGKFHKHLQDLFAPLVVRYVDLMESSIAQSIHRGFERESWEPVKSLTSNLP 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 pF1KA1 NVNLPNVNLPKVPNLPVNIPLGIPQMPTFSAPSWMAAIYDADNGSGTSEDLFWKLDALQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NVNLPNVNLPKVPNLPVNIPLGIPQMPTFSAPSWMAAIYDADNGSGTSEDLFWKLDALQT 1020 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 pF1KA1 FIRDLHWPEEEFGKHLEQRLKLMASDMIESCVKRTRIAFEVKLQKTSRSTDFRVPQSICT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FIRDLHWPEEEFGKHLEQRLKLMASDMIESCVKRTRIAFEVKLQKTSRSTDFRVPQSICT 1080 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 pF1KA1 MFNVMVDAKAQSTKLCSMEMGQEHQYHSKIDELIEETVKEMITLLVAKFVTILEGVLAKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MFNVMVDAKAQSTKLCSMEMGQEHQYHSKIDELIEETVKEMITLLVAKFVTILEGVLAKL 1140 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 pF1KA1 SRYDEGTLFSSFLSFTVKAASKYVDVPKPGMDVADAYVTFVRHSQDVLRDKVNEEMYIER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SRYDEGTLFSSFLSFTVKAASKYVDVPKPGMDVADAYVTFVRHSQDVLRDKVNEEMYIER 1200 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 pF1KA1 LFDQWYNSSMNVICTWLTDRMDLQLHIYQLKTLIRVVKKTYRDFRLQGVLDSTLNSKTYE :::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::: XP_016 LFDQWYNSSMNVICTWLTDRMDLQLHIYQLKTLIRMVKKTYRDFRLQGVLDSTLNSKTYE 1260 1270 1280 1290 1300 1310 1320 1330 1340 1350 pF1KA1 TIRNRLTVEEATASVSEGGGLQGISMKDSDEEDEEDD ::::::::::::::::::::::::::::::::::::: XP_016 TIRNRLTVEEATASVSEGGGLQGISMKDSDEEDEEDD 1320 1330 1340 1350 >>XP_016862863 (OMIM: 604667) PREDICTED: calcium-depende (1350 aa) initn: 7235 init1: 4303 opt: 8853 Z-score: 5209.6 bits: 976.3 E(85289): 0 Smith-Waterman score: 8853; 99.0% identity (99.1% similar) in 1357 aa overlap (1-1353:1-1350) 10 20 30 40 50 60 pF1KA1 MLDPSSSEEESDEIVEEESGKEVLGSAPSGARLSPSRTSEGSAGSAGLGGGGAGAGAGVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLDPSSSEEESDEIVEEESGKEVLGSAPSGARLSPSRTSEGSAGSAGLGGGGAGAGAGVG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 AGGGGGSGASSGGGAGGLQPSSRAGGGRPSSPSPSVVSEKEKEELERLQKEEEERKKRLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGGGGGSGASSGGGAGGLQPSSRAGGGRPSSPSPSVVSEKEKEELERLQKEEEERKKRLQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 LYVFVMRCIAYPFNAKQPTDMARRQQKISKQQLQTVKDRFQAFLNGETQIMADEAFMNAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LYVFVMRCIAYPFNAKQPTDMARRQQKISKQQLQTVKDRFQAFLNGETQIMADEAFMNAV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 QSYYEVFLKSDRVARMVQSGGCSANDSREVFKKHIEKRVRSLPEIDGLSKETVLSSWMAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSYYEVFLKSDRVARMVQSGGCSANDSREVFKKHIEKRVRSLPEIDGLSKETVLSSWMAK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 FDAIYRGEEDPRKQQARMTASAASELILSKEQLYEMFQNILGIKKFEHQLLYNACQLDNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FDAIYRGEEDPRKQQARMTASAASELILSKEQLYEMFQNILGIKKFEHQLLYNACQLDNP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 DEQAAQIRRELDGRLQMADQIARERKFPKFVSKEMENMYIEELKSSVNLLMANLESMPVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DEQAAQIRRELDGRLQMADQIARERKFPKFVSKEMENMYIEELKSSVNLLMANLESMPVS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 KGGEFKLQKLKRSHNASIIDMGEESENQLSKSDVVLSFSLEVVIMEVQGLKSLAPNRIVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KGGEFKLQKLKRSHNASIIDMGEESENQLSKSDVVLSFSLEVVIMEVQGLKSLAPNRIVY 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 CTMEVEGGEKLQTDQAEASKPTWGTQGDFSTTHALPAVKVKLFTESTGVLALEDKELGRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CTMEVEGGEKLQTDQAEASKPTWGTQGDFSTTHALPAVKVKLFTESTGVLALEDKELGRV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 ILHPTPNSPKQSEWHKMTVSKNCPDQDLKIKLAVRMDKPQNMKHSGYLWAIGKNVWKRWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILHPTPNSPKQSEWHKMTVSKNCPDQDLKIKLAVRMDKPQNMKHSGYLWAIGKNVWKRWK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 KRFFVLVQVSQYTFAMCSYREKKAEPQELLQLDGYTVDYTDPQPGLEGGRAFFNAVKEGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KRFFVLVQVSQYTFAMCSYREKKAEPQELLQLDGYTVDYTDPQPGLEGGRAFFNAVKEGD 550 560 570 580 590 600 610 620 630 640 650 pF1KA1 TVIFASDDEQDRILWVQAMYRATGQSHKPVPPTQVQKLNAKGGNVPQLDAPISQFY---- ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TVIFASDDEQDRILWVQAMYRATGQSHKPVPPTQVQKLNAKGGNVPQLDAPISQFSGLKD 610 620 630 640 650 660 660 670 680 690 700 710 pF1KA1 ADRAQKHGMDEFISSNPCNFDHASLFEMVQRLTLDHRLNDSYSCLGWFSPGQVFVLDEYC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ADRAQKHGMDEFISSNPCNFDHASLFEMVQRLTLDHRLNDSYSCLGWFSPGQVFVLDEYC 670 680 690 700 710 720 720 730 740 750 760 770 pF1KA1 ARNGVRGCHRHLCYLRDLLERAENGAMIDPTLLHYSFAFCASHVHGNRPDGIGTVTVEEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ARNGVRGCHRHLCYLRDLLERAENGAMIDPTLLHYSFAFCASHVHGNRPDGIGTVTVEEK 730 740 750 760 770 780 780 790 800 810 820 830 pF1KA1 ERFEEIKERLRVLLENQITHFRYCFPFGRPEGALKATLSLLERVLMKDIVTPVPQEEVKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ERFEEIKERLRVLLENQITHFRYCFPFGRPEGALKATLSLLERVLMKDIVTPVPQEEVKT 790 800 810 820 830 840 840 850 860 870 880 890 pF1KA1 VIRKCLEQAALVNYSRLSEYAKIEENQKDAENVGRLITPAKKLEDTIRLAELVIEVLQQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VIRKCLEQAALVNYSRLSEYAKIEENQKDAENVGRLITPAKKLEDTIRLAELVIEVLQQN 850 860 870 880 890 900 900 910 920 930 940 950 pF1KA1 EEHHAEPHVDKGEAFAWWSDLMVEHAETFLSLFAVDMDAALEVQPPDTWDSFPLFQLLND ::::: :::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEHHA-------EAFAWWSDLMVEHAETFLSLFAVDMDAALEVQPPDTWDSFPLFQLLND 910 920 930 940 950 960 970 980 990 1000 1010 pF1KA1 FLRTDYNLCNGKFHKHLQDLFAPLVVRYVDLMESSIAQSIHRGFERESWEPVKSLTSNLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FLRTDYNLCNGKFHKHLQDLFAPLVVRYVDLMESSIAQSIHRGFERESWEPVKSLTSNLP 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 pF1KA1 NVNLPNVNLPKVPNLPVNIPLGIPQMPTFSAPSWMAAIYDADNGSGTSEDLFWKLDALQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NVNLPNVNLPKVPNLPVNIPLGIPQMPTFSAPSWMAAIYDADNGSGTSEDLFWKLDALQT 1020 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 pF1KA1 FIRDLHWPEEEFGKHLEQRLKLMASDMIESCVKRTRIAFEVKLQKTSRSTDFRVPQSICT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FIRDLHWPEEEFGKHLEQRLKLMASDMIESCVKRTRIAFEVKLQKTSRSTDFRVPQSICT 1080 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 pF1KA1 MFNVMVDAKAQSTKLCSMEMGQEHQYHSKIDELIEETVKEMITLLVAKFVTILEGVLAKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MFNVMVDAKAQSTKLCSMEMGQEHQYHSKIDELIEETVKEMITLLVAKFVTILEGVLAKL 1140 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 pF1KA1 SRYDEGTLFSSFLSFTVKAASKYVDVPKPGMDVADAYVTFVRHSQDVLRDKVNEEMYIER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SRYDEGTLFSSFLSFTVKAASKYVDVPKPGMDVADAYVTFVRHSQDVLRDKVNEEMYIER 1200 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 pF1KA1 LFDQWYNSSMNVICTWLTDRMDLQLHIYQLKTLIRVVKKTYRDFRLQGVLDSTLNSKTYE :::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::: XP_016 LFDQWYNSSMNVICTWLTDRMDLQLHIYQLKTLIRMVKKTYRDFRLQGVLDSTLNSKTYE 1260 1270 1280 1290 1300 1310 1320 1330 1340 1350 pF1KA1 TIRNRLTVEEATASVSEGGGLQGISMKDSDEEDEEDD ::::::::::::::::::::::::::::::::::::: XP_016 TIRNRLTVEEATASVSEGGGLQGISMKDSDEEDEEDD 1320 1330 1340 1350 >>XP_011532495 (OMIM: 604667) PREDICTED: calcium-depende (1358 aa) initn: 7031 init1: 5812 opt: 8843 Z-score: 5203.7 bits: 975.3 E(85289): 0 Smith-Waterman score: 8843; 98.8% identity (98.9% similar) in 1362 aa overlap (1-1353:1-1358) 10 20 30 40 50 60 pF1KA1 MLDPSSSEEESDEIVEEESGKEVLGSAPSGARLSPSRTSEGSAGSAGLGGGGAGAGAGVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MLDPSSSEEESDEIVEEESGKEVLGSAPSGARLSPSRTSEGSAGSAGLGGGGAGAGAGVG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 AGGGGGSGASSGGGAGGLQPSSRAGGGRPSSPSPSVVSEKEKEELERLQKEEEERKKRLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AGGGGGSGASSGGGAGGLQPSSRAGGGRPSSPSPSVVSEKEKEELERLQKEEEERKKRLQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 LYVFVMRCIAYPFNAKQPTDMARRQQKISKQQLQTVKDRFQAFLNGETQIMADEAFMNAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LYVFVMRCIAYPFNAKQPTDMARRQQKISKQQLQTVKDRFQAFLNGETQIMADEAFMNAV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 QSYYEVFLKSDRVARMVQSGGCSANDSREVFKKHIEKRVRSLPEIDGLSKETVLSSWMAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSYYEVFLKSDRVARMVQSGGCSANDSREVFKKHIEKRVRSLPEIDGLSKETVLSSWMAK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 FDAIYRGEEDPRKQQARMTASAASELILSKEQLYEMFQNILGIKKFEHQLLYNACQLDNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FDAIYRGEEDPRKQQARMTASAASELILSKEQLYEMFQNILGIKKFEHQLLYNACQLDNP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 DEQAAQIRRELDGRLQMADQIARERKFPKFVSKEMENMYIEELKSSVNLLMANLESMPVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DEQAAQIRRELDGRLQMADQIARERKFPKFVSKEMENMYIEELKSSVNLLMANLESMPVS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 KGGEFKLQKLKRSHNASIIDMGEESENQLSKSDVVLSFSLEVVIMEVQGLKSLAPNRIVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KGGEFKLQKLKRSHNASIIDMGEESENQLSKSDVVLSFSLEVVIMEVQGLKSLAPNRIVY 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 CTMEVEGGEKLQTDQAEASKPTWGTQGDFSTTHALPAVKVKLFTESTGVLALEDKELGRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CTMEVEGGEKLQTDQAEASKPTWGTQGDFSTTHALPAVKVKLFTESTGVLALEDKELGRV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 ILHPTPNSPKQSEWHKMTVSKNCPDQDLKIKLAVRMDKPQNMKHSGYLWAIGKNVWKRWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILHPTPNSPKQSEWHKMTVSKNCPDQDLKIKLAVRMDKPQNMKHSGYLWAIGKNVWKRWK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 KRFFVLVQVSQYTFAMCSYREKKAEPQELLQLDGYTVDYTDPQPGLEGGRAFFNAVKEGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KRFFVLVQVSQYTFAMCSYREKKAEPQELLQLDGYTVDYTDPQPGLEGGRAFFNAVKEGD 550 560 570 580 590 600 610 620 630 640 650 pF1KA1 TVIFASDDEQDRILWVQAMYRATGQSHKPVPPTQVQKLNAKGGNVPQLDAPISQFY---- ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TVIFASDDEQDRILWVQAMYRATGQSHKPVPPTQVQKLNAKGGNVPQLDAPISQFSGLKD 610 620 630 640 650 660 660 670 680 690 700 710 pF1KA1 ADRAQKHGMDEFISSNPCNFDHASLFEMVQRLTLDHRLNDSYSCLGWFSPGQVFVLDEYC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ADRAQKHGMDEFISSNPCNFDHASLFEMVQRLTLDHRLNDSYSCLGWFSPGQVFVLDEYC 670 680 690 700 710 720 720 730 740 750 760 770 pF1KA1 ARNGVRGCHRHLCYLRDLLERAENGAMIDPTLLHYSFAFCASHVHGNRPDGIGTVTVEEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ARNGVRGCHRHLCYLRDLLERAENGAMIDPTLLHYSFAFCASHVHGNRPDGIGTVTVEEK 730 740 750 760 770 780 780 790 800 810 820 830 pF1KA1 ERFEEIKERLRVLLENQITHFRYCFPFGRPEGALKATLSLLERVLMKDIVTPVPQEEVKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ERFEEIKERLRVLLENQITHFRYCFPFGRPEGALKATLSLLERVLMKDIVTPVPQEEVKT 790 800 810 820 830 840 840 850 860 870 880 890 pF1KA1 VIRKCLEQAALVNYSRLSEYAKIEENQKDAENVGRLITPAKKLEDTIRLAELVIEVLQQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VIRKCLEQAALVNYSRLSEYAKIEENQKDAENVGRLITPAKKLEDTIRLAELVIEVLQQN 850 860 870 880 890 900 900 910 920 930 940 950 pF1KA1 EEHHAEPHVDKGEAFAWWSDLMVEHAETFLSLFAVDMDAALEVQPPDTWDSFPLFQLLND :::::: . :::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEHHAEGK----EAFAWWSDLMVEHAETFLSLFAVDMDAALEVQPPDTWDSFPLFQLLND 910 920 930 940 950 960 970 980 990 1000 1010 pF1KA1 FLRTDYNLCNGKFHKHLQDLFAPLVVRYVDLMESSIAQSIHRGFERESWEPVKSLTSNLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FLRTDYNLCNGKFHKHLQDLFAPLVVRYVDLMESSIAQSIHRGFERESWEPVKSLTSNLP 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 pF1KA1 NVNLPNVNLPKVPNLPVNIPLGIPQMPTFSAPSWMAAIYDADNGSGTSEDLFWKLDALQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NVNLPNVNLPKVPNLPVNIPLGIPQMPTFSAPSWMAAIYDADNGSGTSEDLFWKLDALQT 1020 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 pF1KA1 FIRDLHWPEEEFGKHLEQRLKLMASDMIESCVKRTRIAFEVKLQKTSRSTDFRVPQSICT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FIRDLHWPEEEFGKHLEQRLKLMASDMIESCVKRTRIAFEVKLQKTSRSTDFRVPQSICT 1080 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 pF1KA1 MFNVMVDAKAQSTKLCSMEMGQE-----HQYHSKIDELIEETVKEMITLLVAKFVTILEG ::::::::::::::::::::::: :::::::::::::::::::::::::::::::: XP_011 MFNVMVDAKAQSTKLCSMEMGQEFAKMWHQYHSKIDELIEETVKEMITLLVAKFVTILEG 1140 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 pF1KA1 VLAKLSRYDEGTLFSSFLSFTVKAASKYVDVPKPGMDVADAYVTFVRHSQDVLRDKVNEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLAKLSRYDEGTLFSSFLSFTVKAASKYVDVPKPGMDVADAYVTFVRHSQDVLRDKVNEE 1200 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 pF1KA1 MYIERLFDQWYNSSMNVICTWLTDRMDLQLHIYQLKTLIRVVKKTYRDFRLQGVLDSTLN ::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::: XP_011 MYIERLFDQWYNSSMNVICTWLTDRMDLQLHIYQLKTLIRMVKKTYRDFRLQGVLDSTLN 1260 1270 1280 1290 1300 1310 1320 1330 1340 1350 pF1KA1 SKTYETIRNRLTVEEATASVSEGGGLQGISMKDSDEEDEEDD :::::::::::::::::::::::::::::::::::::::::: XP_011 SKTYETIRNRLTVEEATASVSEGGGLQGISMKDSDEEDEEDD 1320 1330 1340 1350 >>XP_011532505 (OMIM: 604667) PREDICTED: calcium-depende (1347 aa) initn: 8642 init1: 4303 opt: 8802 Z-score: 5179.7 bits: 970.8 E(85289): 0 Smith-Waterman score: 8802; 98.7% identity (98.8% similar) in 1357 aa overlap (1-1353:1-1347) 10 20 30 40 50 60 pF1KA1 MLDPSSSEEESDEIVEEESGKEVLGSAPSGARLSPSRTSEGSAGSAGLGGGGAGAGAGVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MLDPSSSEEESDEIVEEESGKEVLGSAPSGARLSPSRTSEGSAGSAGLGGGGAGAGAGVG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 AGGGGGSGASSGGGAGGLQPSSRAGGGRPSSPSPSVVSEKEKEELERLQKEEEERKKRLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AGGGGGSGASSGGGAGGLQPSSRAGGGRPSSPSPSVVSEKEKEELERLQKEEEERKKRLQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 LYVFVMRCIAYPFNAKQPTDMARRQQKISKQQLQTVKDRFQAFLNGETQIMADEAFMNAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LYVFVMRCIAYPFNAKQPTDMARRQQKISKQQLQTVKDRFQAFLNGETQIMADEAFMNAV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 QSYYEVFLKSDRVARMVQSGGCSANDSREVFKKHIEKRVRSLPEIDGLSKETVLSSWMAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSYYEVFLKSDRVARMVQSGGCSANDSREVFKKHIEKRVRSLPEIDGLSKETVLSSWMAK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 FDAIYRGEEDPRKQQARMTASAASELILSKEQLYEMFQNILGIKKFEHQLLYNACQLDNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FDAIYRGEEDPRKQQARMTASAASELILSKEQLYEMFQNILGIKKFEHQLLYNACQLDNP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 DEQAAQIRRELDGRLQMADQIARERKFPKFVSKEMENMYIEELKSSVNLLMANLESMPVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DEQAAQIRRELDGRLQMADQIARERKFPKFVSKEMENMYIEELKSSVNLLMANLESMPVS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 KGGEFKLQKLKRSHNASIIDMGEESENQLSKSDVVLSFSLEVVIMEVQGLKSLAPNRIVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KGGEFKLQKLKRSHNASIIDMGEESENQLSKSDVVLSFSLEVVIMEVQGLKSLAPNRIVY 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 CTMEVEGGEKLQTDQAEASKPTWGTQGDFSTTHALPAVKVKLFTESTGVLALEDKELGRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CTMEVEGGEKLQTDQAEASKPTWGTQGDFSTTHALPAVKVKLFTESTGVLALEDKELGRV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 ILHPTPNSPKQSEWHKMTVSKNCPDQDLKIKLAVRMDKPQNMKHSGYLWAIGKNVWKRWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILHPTPNSPKQSEWHKMTVSKNCPDQDLKIKLAVRMDKPQNMKHSGYLWAIGKNVWKRWK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 KRFFVLVQVSQYTFAMCSYREKKAEPQELLQLDGYTVDYTDPQPGLEGGRAFFNAVKEGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KRFFVLVQVSQYTFAMCSYREKKAEPQELLQLDGYTVDYTDPQPGLEGGRAFFNAVKEGD 550 560 570 580 590 600 610 620 630 640 650 pF1KA1 TVIFASDDEQDRILWVQAMYRATGQSHKPVPPTQVQKLNAKGGNVPQLDAPISQFY---- ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TVIFASDDEQDRILWVQAMYRATGQSHKPVPPTQVQKLNAKGGNVPQLDAPISQFSGLKD 610 620 630 640 650 660 660 670 680 690 700 710 pF1KA1 ADRAQKHGMDEFISSNPCNFDHASLFEMVQRLTLDHRLNDSYSCLGWFSPGQVFVLDEYC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ADRAQKHGMDEFISSNPCNFDHASLFEMVQRLTLDHRLNDSYSCLGWFSPGQVFVLDEYC 670 680 690 700 710 720 720 730 740 750 760 770 pF1KA1 ARNGVRGCHRHLCYLRDLLERAENGAMIDPTLLHYSFAFCASHVHGNRPDGIGTVTVEEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ARNGVRGCHRHLCYLRDLLERAENGAMIDPTLLHYSFAFCASHVHGNRPDGIGTVTVEEK 730 740 750 760 770 780 780 790 800 810 820 830 pF1KA1 ERFEEIKERLRVLLENQITHFRYCFPFGRPEGALKATLSLLERVLMKDIVTPVPQEEVKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ERFEEIKERLRVLLENQITHFRYCFPFGRPEGALKATLSLLERVLMKDIVTPVPQEEVKT 790 800 810 820 830 840 840 850 860 870 880 890 pF1KA1 VIRKCLEQAALVNYSRLSEYAKIEENQKDAENVGRLITPAKKLEDTIRLAELVIEVLQQN :::::::::::::::::::::::: :::::::::::::::::::::::::::::: XP_011 VIRKCLEQAALVNYSRLSEYAKIE------ENVGRLITPAKKLEDTIRLAELVIEVLQQN 850 860 870 880 890 900 910 920 930 940 950 pF1KA1 EEHHAEPHVDKGEAFAWWSDLMVEHAETFLSLFAVDMDAALEVQPPDTWDSFPLFQLLND :::::: . :::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEHHAEGK----EAFAWWSDLMVEHAETFLSLFAVDMDAALEVQPPDTWDSFPLFQLLND 900 910 920 930 940 950 960 970 980 990 1000 1010 pF1KA1 FLRTDYNLCNGKFHKHLQDLFAPLVVRYVDLMESSIAQSIHRGFERESWEPVKSLTSNLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FLRTDYNLCNGKFHKHLQDLFAPLVVRYVDLMESSIAQSIHRGFERESWEPVKSLTSNLP 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 pF1KA1 NVNLPNVNLPKVPNLPVNIPLGIPQMPTFSAPSWMAAIYDADNGSGTSEDLFWKLDALQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NVNLPNVNLPKVPNLPVNIPLGIPQMPTFSAPSWMAAIYDADNGSGTSEDLFWKLDALQT 1020 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 pF1KA1 FIRDLHWPEEEFGKHLEQRLKLMASDMIESCVKRTRIAFEVKLQKTSRSTDFRVPQSICT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FIRDLHWPEEEFGKHLEQRLKLMASDMIESCVKRTRIAFEVKLQKTSRSTDFRVPQSICT 1080 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 pF1KA1 MFNVMVDAKAQSTKLCSMEMGQEHQYHSKIDELIEETVKEMITLLVAKFVTILEGVLAKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MFNVMVDAKAQSTKLCSMEMGQEHQYHSKIDELIEETVKEMITLLVAKFVTILEGVLAKL 1140 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 pF1KA1 SRYDEGTLFSSFLSFTVKAASKYVDVPKPGMDVADAYVTFVRHSQDVLRDKVNEEMYIER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRYDEGTLFSSFLSFTVKAASKYVDVPKPGMDVADAYVTFVRHSQDVLRDKVNEEMYIER 1200 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 pF1KA1 LFDQWYNSSMNVICTWLTDRMDLQLHIYQLKTLIRVVKKTYRDFRLQGVLDSTLNSKTYE :::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::: XP_011 LFDQWYNSSMNVICTWLTDRMDLQLHIYQLKTLIRMVKKTYRDFRLQGVLDSTLNSKTYE 1260 1270 1280 1290 1300 1310 1320 1330 1340 1350 pF1KA1 TIRNRLTVEEATASVSEGGGLQGISMKDSDEEDEEDD ::::::::::::::::::::::::::::::::::::: XP_011 TIRNRLTVEEATASVSEGGGLQGISMKDSDEEDEEDD 1320 1330 1340 >>XP_011532498 (OMIM: 604667) PREDICTED: calcium-depende (1352 aa) initn: 8628 init1: 4303 opt: 8782 Z-score: 5168.0 bits: 968.6 E(85289): 0 Smith-Waterman score: 8782; 98.3% identity (98.5% similar) in 1362 aa overlap (1-1353:1-1352) 10 20 30 40 50 60 pF1KA1 MLDPSSSEEESDEIVEEESGKEVLGSAPSGARLSPSRTSEGSAGSAGLGGGGAGAGAGVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MLDPSSSEEESDEIVEEESGKEVLGSAPSGARLSPSRTSEGSAGSAGLGGGGAGAGAGVG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 AGGGGGSGASSGGGAGGLQPSSRAGGGRPSSPSPSVVSEKEKEELERLQKEEEERKKRLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AGGGGGSGASSGGGAGGLQPSSRAGGGRPSSPSPSVVSEKEKEELERLQKEEEERKKRLQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 LYVFVMRCIAYPFNAKQPTDMARRQQKISKQQLQTVKDRFQAFLNGETQIMADEAFMNAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LYVFVMRCIAYPFNAKQPTDMARRQQKISKQQLQTVKDRFQAFLNGETQIMADEAFMNAV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 QSYYEVFLKSDRVARMVQSGGCSANDSREVFKKHIEKRVRSLPEIDGLSKETVLSSWMAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSYYEVFLKSDRVARMVQSGGCSANDSREVFKKHIEKRVRSLPEIDGLSKETVLSSWMAK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 FDAIYRGEEDPRKQQARMTASAASELILSKEQLYEMFQNILGIKKFEHQLLYNACQLDNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FDAIYRGEEDPRKQQARMTASAASELILSKEQLYEMFQNILGIKKFEHQLLYNACQLDNP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 DEQAAQIRRELDGRLQMADQIARERKFPKFVSKEMENMYIEELKSSVNLLMANLESMPVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DEQAAQIRRELDGRLQMADQIARERKFPKFVSKEMENMYIEELKSSVNLLMANLESMPVS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 KGGEFKLQKLKRSHNASIIDMGEESENQLSKSDVVLSFSLEVVIMEVQGLKSLAPNRIVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KGGEFKLQKLKRSHNASIIDMGEESENQLSKSDVVLSFSLEVVIMEVQGLKSLAPNRIVY 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 CTMEVEGGEKLQTDQAEASKPTWGTQGDFSTTHALPAVKVKLFTESTGVLALEDKELGRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CTMEVEGGEKLQTDQAEASKPTWGTQGDFSTTHALPAVKVKLFTESTGVLALEDKELGRV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 ILHPTPNSPKQSEWHKMTVSKNCPDQDLKIKLAVRMDKPQNMKHSGYLWAIGKNVWKRWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILHPTPNSPKQSEWHKMTVSKNCPDQDLKIKLAVRMDKPQNMKHSGYLWAIGKNVWKRWK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 KRFFVLVQVSQYTFAMCSYREKKAEPQELLQLDGYTVDYTDPQPGLEGGRAFFNAVKEGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KRFFVLVQVSQYTFAMCSYREKKAEPQELLQLDGYTVDYTDPQPGLEGGRAFFNAVKEGD 550 560 570 580 590 600 610 620 630 640 650 pF1KA1 TVIFASDDEQDRILWVQAMYRATGQSHKPVPPTQVQKLNAKGGNVPQLDAPISQFY---- ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TVIFASDDEQDRILWVQAMYRATGQSHKPVPPTQVQKLNAKGGNVPQLDAPISQFSGLKD 610 620 630 640 650 660 660 670 680 690 700 710 pF1KA1 ADRAQKHGMDEFISSNPCNFDHASLFEMVQRLTLDHRLNDSYSCLGWFSPGQVFVLDEYC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ADRAQKHGMDEFISSNPCNFDHASLFEMVQRLTLDHRLNDSYSCLGWFSPGQVFVLDEYC 670 680 690 700 710 720 720 730 740 750 760 770 pF1KA1 ARNGVRGCHRHLCYLRDLLERAENGAMIDPTLLHYSFAFCASHVHGNRPDGIGTVTVEEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ARNGVRGCHRHLCYLRDLLERAENGAMIDPTLLHYSFAFCASHVHGNRPDGIGTVTVEEK 730 740 750 760 770 780 780 790 800 810 820 830 pF1KA1 ERFEEIKERLRVLLENQITHFRYCFPFGRPEGALKATLSLLERVLMKDIVTPVPQEEVKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ERFEEIKERLRVLLENQITHFRYCFPFGRPEGALKATLSLLERVLMKDIVTPVPQEEVKT 790 800 810 820 830 840 840 850 860 870 880 890 pF1KA1 VIRKCLEQAALVNYSRLSEYAKIEENQKDAENVGRLITPAKKLEDTIRLAELVIEVLQQN :::::::::::::::::::::::: :::::::::::::::::::::::::::::: XP_011 VIRKCLEQAALVNYSRLSEYAKIE------ENVGRLITPAKKLEDTIRLAELVIEVLQQN 850 860 870 880 890 900 910 920 930 940 950 pF1KA1 EEHHAEPHVDKGEAFAWWSDLMVEHAETFLSLFAVDMDAALEVQPPDTWDSFPLFQLLND :::::: . :::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEHHAEGK----EAFAWWSDLMVEHAETFLSLFAVDMDAALEVQPPDTWDSFPLFQLLND 900 910 920 930 940 950 960 970 980 990 1000 1010 pF1KA1 FLRTDYNLCNGKFHKHLQDLFAPLVVRYVDLMESSIAQSIHRGFERESWEPVKSLTSNLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FLRTDYNLCNGKFHKHLQDLFAPLVVRYVDLMESSIAQSIHRGFERESWEPVKSLTSNLP 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 pF1KA1 NVNLPNVNLPKVPNLPVNIPLGIPQMPTFSAPSWMAAIYDADNGSGTSEDLFWKLDALQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NVNLPNVNLPKVPNLPVNIPLGIPQMPTFSAPSWMAAIYDADNGSGTSEDLFWKLDALQT 1020 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 pF1KA1 FIRDLHWPEEEFGKHLEQRLKLMASDMIESCVKRTRIAFEVKLQKTSRSTDFRVPQSICT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FIRDLHWPEEEFGKHLEQRLKLMASDMIESCVKRTRIAFEVKLQKTSRSTDFRVPQSICT 1080 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 pF1KA1 MFNVMVDAKAQSTKLCSMEMGQE-----HQYHSKIDELIEETVKEMITLLVAKFVTILEG ::::::::::::::::::::::: :::::::::::::::::::::::::::::::: XP_011 MFNVMVDAKAQSTKLCSMEMGQEFAKMWHQYHSKIDELIEETVKEMITLLVAKFVTILEG 1140 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 pF1KA1 VLAKLSRYDEGTLFSSFLSFTVKAASKYVDVPKPGMDVADAYVTFVRHSQDVLRDKVNEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLAKLSRYDEGTLFSSFLSFTVKAASKYVDVPKPGMDVADAYVTFVRHSQDVLRDKVNEE 1200 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 pF1KA1 MYIERLFDQWYNSSMNVICTWLTDRMDLQLHIYQLKTLIRVVKKTYRDFRLQGVLDSTLN ::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::: XP_011 MYIERLFDQWYNSSMNVICTWLTDRMDLQLHIYQLKTLIRMVKKTYRDFRLQGVLDSTLN 1260 1270 1280 1290 1300 1310 1320 1330 1340 1350 pF1KA1 SKTYETIRNRLTVEEATASVSEGGGLQGISMKDSDEEDEEDD :::::::::::::::::::::::::::::::::::::::::: XP_011 SKTYETIRNRLTVEEATASVSEGGGLQGISMKDSDEEDEEDD 1320 1330 1340 1350 1353 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 20:43:51 2016 done: Sat Nov 5 20:43:53 2016 Total Scan time: 15.840 Total Display time: 0.780 Function used was FASTA [36.3.4 Apr, 2011]