FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1122, 1028 aa 1>>>pF1KA1122 1028 - 1028 aa - 1028 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.1058+/-0.000477; mu= 14.6273+/- 0.030 mean_var=139.0291+/-27.632, 0's: 0 Z-trim(113.3): 252 B-trim: 195 in 1/55 Lambda= 0.108773 statistics sampled from 22384 (22641) to 22384 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.612), E-opt: 0.2 (0.265), width: 16 Scan time: 12.060 The best scores are: opt bits E(85289) NP_001121901 (OMIM: 136000,612761) SWI/SNF-related (1028) 6713 1066.2 0 NP_001121902 (OMIM: 136000,612761) SWI/SNF-related (1028) 6713 1066.2 0 XP_016863952 (OMIM: 136000,612761) PREDICTED: SWI/ (1026) 6689 1062.4 0 NP_064544 (OMIM: 136000,612761) SWI/SNF-related ma (1026) 6689 1062.4 0 NP_001241878 (OMIM: 136000,612761) SWI/SNF-related ( 596) 3907 625.7 2.4e-178 XP_016863954 (OMIM: 136000,612761) PREDICTED: SWI/ ( 505) 3307 531.5 4.6e-150 XP_016863953 (OMIM: 136000,612761) PREDICTED: SWI/ ( 505) 3307 531.5 4.6e-150 XP_016872368 (OMIM: 605191) PREDICTED: TATA-bindin (1519) 874 150.0 9.3e-35 XP_016872370 (OMIM: 605191) PREDICTED: TATA-bindin (1519) 874 150.0 9.3e-35 XP_016872369 (OMIM: 605191) PREDICTED: TATA-bindin (1519) 874 150.0 9.3e-35 XP_016872367 (OMIM: 605191) PREDICTED: TATA-bindin (1646) 874 150.0 9.9e-35 XP_011538630 (OMIM: 605191) PREDICTED: TATA-bindin (1693) 874 150.0 1e-34 XP_011538629 (OMIM: 605191) PREDICTED: TATA-bindin (1725) 874 150.1 1e-34 XP_016872366 (OMIM: 605191) PREDICTED: TATA-bindin (1800) 874 150.1 1.1e-34 XP_011538628 (OMIM: 605191) PREDICTED: TATA-bindin (1812) 874 150.1 1.1e-34 NP_003963 (OMIM: 605191) TATA-binding protein-asso (1849) 874 150.1 1.1e-34 XP_011519987 (OMIM: 610169) PREDICTED: DNA helicas (1209) 772 133.9 5.1e-30 NP_060139 (OMIM: 300687) DNA excision repair prote (1250) 730 127.3 5.1e-28 NP_001276002 (OMIM: 603946,616911) lymphoid-specif ( 700) 675 118.5 1.3e-25 NP_001276000 (OMIM: 603946,616911) lymphoid-specif ( 714) 674 118.4 1.5e-25 NP_001275997 (OMIM: 603946,616911) lymphoid-specif ( 822) 674 118.4 1.6e-25 NP_060533 (OMIM: 603946,616911) lymphoid-specific ( 838) 674 118.4 1.6e-25 NP_001010895 (OMIM: 615667,615715) DNA excision re ( 712) 600 106.8 4.5e-22 XP_011516949 (OMIM: 615667,615715) PREDICTED: DNA (1178) 600 106.9 6.7e-22 XP_011516948 (OMIM: 615667,615715) PREDICTED: DNA (1184) 600 106.9 6.7e-22 XP_011516947 (OMIM: 615667,615715) PREDICTED: DNA (1253) 600 106.9 7e-22 NP_064592 (OMIM: 615667,615715) DNA excision repai (1561) 600 107.0 8.3e-22 XP_011516943 (OMIM: 615667,615715) PREDICTED: DNA (1510) 596 106.4 1.3e-21 NP_001275996 (OMIM: 603946,616911) lymphoid-specif ( 884) 567 101.7 1.9e-20 XP_011519988 (OMIM: 610169) PREDICTED: DNA helicas ( 906) 521 94.4 2.9e-18 NP_060023 (OMIM: 610169) DNA helicase INO80 [Homo (1556) 521 94.6 4.5e-18 NP_006653 (OMIM: 136140,611421) helicase SRCAP [Ho (3230) 526 95.6 4.6e-18 NP_001276004 (OMIM: 603946,616911) lymphoid-specif ( 432) 505 91.7 9.5e-18 NP_001276003 (OMIM: 603946,616911) lymphoid-specif ( 477) 505 91.7 1e-17 NP_001276001 (OMIM: 603946,616911) lymphoid-specif ( 708) 505 91.9 1.4e-17 NP_001275999 (OMIM: 603946,616911) lymphoid-specif ( 740) 505 91.9 1.4e-17 NP_001275998 (OMIM: 603946,616911) lymphoid-specif ( 806) 505 91.9 1.5e-17 XP_011516946 (OMIM: 615667,615715) PREDICTED: DNA (1263) 508 92.5 1.6e-17 NP_003592 (OMIM: 603375) SWI/SNF-related matrix-as (1052) 461 85.1 2.3e-15 XP_016885240 (OMIM: 300012) PREDICTED: probable gl (1036) 453 83.8 5.3e-15 XP_016885239 (OMIM: 300012) PREDICTED: probable gl (1042) 453 83.8 5.3e-15 XP_006724845 (OMIM: 300012) PREDICTED: probable gl (1042) 453 83.8 5.3e-15 NP_001269804 (OMIM: 300012) probable global transc (1058) 453 83.8 5.4e-15 NP_065971 (OMIM: 610528,615032) chromodomain-helic (2302) 453 84.1 9.9e-15 NP_001164100 (OMIM: 610528,615032) chromodomain-he (2581) 453 84.1 1.1e-14 XP_016874223 (OMIM: 603277,617159) PREDICTED: chro (1892) 445 82.8 2e-14 XP_016874222 (OMIM: 603277,617159) PREDICTED: chro (1893) 445 82.8 2e-14 XP_016874221 (OMIM: 603277,617159) PREDICTED: chro (1895) 445 82.8 2e-14 XP_016874220 (OMIM: 603277,617159) PREDICTED: chro (1899) 445 82.8 2e-14 XP_016874219 (OMIM: 603277,617159) PREDICTED: chro (1900) 445 82.8 2e-14 >>NP_001121901 (OMIM: 136000,612761) SWI/SNF-related mat (1028 aa) initn: 6713 init1: 6713 opt: 6713 Z-score: 5699.4 bits: 1066.2 E(85289): 0 Smith-Waterman score: 6713; 100.0% identity (100.0% similar) in 1028 aa overlap (1-1028:1-1028) 10 20 30 40 50 60 pF1KA1 MNLFNLDRFRFEKRNKIEEAPEATPQPSQPGPSSPISLSAEEENAEGEVSRANTPDSDIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNLFNLDRFRFEKRNKIEEAPEATPQPSQPGPSSPISLSAEEENAEGEVSRANTPDSDIT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 EKTEDSSVPETPDNERKASISYFKNQRGIQYIDLSSDSEDVVSPNCSNTVQEKTFNKDTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKTEDSSVPETPDNERKASISYFKNQRGIQYIDLSSDSEDVVSPNCSNTVQEKTFNKDTV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 IIVSEPSEDEESQGLPTMARRNDDISELEDLSELEDLKDAKLQTLKELFPQRSDNDLLKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IIVSEPSEDEESQGLPTMARRNDDISELEDLSELEDLKDAKLQTLKELFPQRSDNDLLKL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 IESTSTMDGAIAAALLMFGDAGGGPRKRKLSSSSEPYEEDEFNDDQSIKKTRLDHGEESN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IESTSTMDGAIAAALLMFGDAGGGPRKRKLSSSSEPYEEDEFNDDQSIKKTRLDHGEESN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 ESAESSSNWEKQESIVLKLQKEFPNFDKQELREVLKEHEWMYTEALESLKVFAEDQDMQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ESAESSSNWEKQESIVLKLQKEFPNFDKQELREVLKEHEWMYTEALESLKVFAEDQDMQY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 VSQSEVPNGKEVSSRSQNYPKNATKTKLKQKFSMKAQNGFNKKRKKNVFNPKRVVEDSEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VSQSEVPNGKEVSSRSQNYPKNATKTKLKQKFSMKAQNGFNKKRKKNVFNPKRVVEDSEY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 DSGSDVGSSLDEDYSSGEEVMEDGYKGKILHFLQDASIGELTLIPQCSQKKAQKITELRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSGSDVGSSLDEDYSSGEEVMEDGYKGKILHFLQDASIGELTLIPQCSQKKAQKITELRP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 FNSWEALFTKMSKTNGLSEDLIWHCKTLIQERDVVIRLMNKCEDISNKLTKQVTMLTGNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FNSWEALFTKMSKTNGLSEDLIWHCKTLIQERDVVIRLMNKCEDISNKLTKQVTMLTGNG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 GGWNIEQPSILNQSLSLKPYQKVGLNWLALVHKHGLNGILADEMGLGKTIQAIAFLAYLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GGWNIEQPSILNQSLSLKPYQKVGLNWLALVHKHGLNGILADEMGLGKTIQAIAFLAYLY 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 QEGNNGPHLIVVPASTIDNWLREVNLWCPTLKVLCYYGSQEERKQIRFNIHSRYEDYNVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QEGNNGPHLIVVPASTIDNWLREVNLWCPTLKVLCYYGSQEERKQIRFNIHSRYEDYNVI 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 VTTYNCAISSSDDRSLFRRLKLNYAIFDEGHMLKNMGSIRYQHLMTINANNRLLLTGTPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTTYNCAISSSDDRSLFRRLKLNYAIFDEGHMLKNMGSIRYQHLMTINANNRLLLTGTPV 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 QNNLLELMSLLNFVMPHMFSSSTSEIRRMFSSKTKSADEQSIYEKERIAHAKQIIKPFIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QNNLLELMSLLNFVMPHMFSSSTSEIRRMFSSKTKSADEQSIYEKERIAHAKQIIKPFIL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 RRVKEEVLKQLPPKKDRIELCAMSEKQEQLYLGLFNRLKKSINNLVTEKNTEMCNVMMQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RRVKEEVLKQLPPKKDRIELCAMSEKQEQLYLGLFNRLKKSINNLVTEKNTEMCNVMMQL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 RKMANHPLLHRQYYTAEKLKEMSQLMLKEPTHCEANPDLIFEDMEVMTDFELHVLCKQYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKMANHPLLHRQYYTAEKLKEMSQLMLKEPTHCEANPDLIFEDMEVMTDFELHVLCKQYR 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 HINNFQLDMDLILDSGKFRVLGCILSELKQKGDRVVLFSQFTMMLDILEVLLKHHQHRYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HINNFQLDMDLILDSGKFRVLGCILSELKQKGDRVVLFSQFTMMLDILEVLLKHHQHRYL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 RLDGKTQISERIHLIDEFNTDMDIFVFLLSTKAGGLGINLTSANVVILHDIDCNPYNDKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLDGKTQISERIHLIDEFNTDMDIFVFLLSTKAGGLGINLTSANVVILHDIDCNPYNDKQ 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 AEDRCHRVGQTKEVLVIKLISQGTIEESMLKINQQKLKLEQDMTTVDEGDEGSMPADIAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AEDRCHRVGQTKEVLVIKLISQGTIEESMLKINQQKLKLEQDMTTVDEGDEGSMPADIAT 970 980 990 1000 1010 1020 pF1KA1 LLKTSMGL :::::::: NP_001 LLKTSMGL >>NP_001121902 (OMIM: 136000,612761) SWI/SNF-related mat (1028 aa) initn: 6713 init1: 6713 opt: 6713 Z-score: 5699.4 bits: 1066.2 E(85289): 0 Smith-Waterman score: 6713; 100.0% identity (100.0% similar) in 1028 aa overlap (1-1028:1-1028) 10 20 30 40 50 60 pF1KA1 MNLFNLDRFRFEKRNKIEEAPEATPQPSQPGPSSPISLSAEEENAEGEVSRANTPDSDIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNLFNLDRFRFEKRNKIEEAPEATPQPSQPGPSSPISLSAEEENAEGEVSRANTPDSDIT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 EKTEDSSVPETPDNERKASISYFKNQRGIQYIDLSSDSEDVVSPNCSNTVQEKTFNKDTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKTEDSSVPETPDNERKASISYFKNQRGIQYIDLSSDSEDVVSPNCSNTVQEKTFNKDTV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 IIVSEPSEDEESQGLPTMARRNDDISELEDLSELEDLKDAKLQTLKELFPQRSDNDLLKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IIVSEPSEDEESQGLPTMARRNDDISELEDLSELEDLKDAKLQTLKELFPQRSDNDLLKL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 IESTSTMDGAIAAALLMFGDAGGGPRKRKLSSSSEPYEEDEFNDDQSIKKTRLDHGEESN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IESTSTMDGAIAAALLMFGDAGGGPRKRKLSSSSEPYEEDEFNDDQSIKKTRLDHGEESN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 ESAESSSNWEKQESIVLKLQKEFPNFDKQELREVLKEHEWMYTEALESLKVFAEDQDMQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ESAESSSNWEKQESIVLKLQKEFPNFDKQELREVLKEHEWMYTEALESLKVFAEDQDMQY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 VSQSEVPNGKEVSSRSQNYPKNATKTKLKQKFSMKAQNGFNKKRKKNVFNPKRVVEDSEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VSQSEVPNGKEVSSRSQNYPKNATKTKLKQKFSMKAQNGFNKKRKKNVFNPKRVVEDSEY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 DSGSDVGSSLDEDYSSGEEVMEDGYKGKILHFLQDASIGELTLIPQCSQKKAQKITELRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSGSDVGSSLDEDYSSGEEVMEDGYKGKILHFLQDASIGELTLIPQCSQKKAQKITELRP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 FNSWEALFTKMSKTNGLSEDLIWHCKTLIQERDVVIRLMNKCEDISNKLTKQVTMLTGNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FNSWEALFTKMSKTNGLSEDLIWHCKTLIQERDVVIRLMNKCEDISNKLTKQVTMLTGNG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 GGWNIEQPSILNQSLSLKPYQKVGLNWLALVHKHGLNGILADEMGLGKTIQAIAFLAYLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GGWNIEQPSILNQSLSLKPYQKVGLNWLALVHKHGLNGILADEMGLGKTIQAIAFLAYLY 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 QEGNNGPHLIVVPASTIDNWLREVNLWCPTLKVLCYYGSQEERKQIRFNIHSRYEDYNVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QEGNNGPHLIVVPASTIDNWLREVNLWCPTLKVLCYYGSQEERKQIRFNIHSRYEDYNVI 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 VTTYNCAISSSDDRSLFRRLKLNYAIFDEGHMLKNMGSIRYQHLMTINANNRLLLTGTPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTTYNCAISSSDDRSLFRRLKLNYAIFDEGHMLKNMGSIRYQHLMTINANNRLLLTGTPV 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 QNNLLELMSLLNFVMPHMFSSSTSEIRRMFSSKTKSADEQSIYEKERIAHAKQIIKPFIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QNNLLELMSLLNFVMPHMFSSSTSEIRRMFSSKTKSADEQSIYEKERIAHAKQIIKPFIL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 RRVKEEVLKQLPPKKDRIELCAMSEKQEQLYLGLFNRLKKSINNLVTEKNTEMCNVMMQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RRVKEEVLKQLPPKKDRIELCAMSEKQEQLYLGLFNRLKKSINNLVTEKNTEMCNVMMQL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 RKMANHPLLHRQYYTAEKLKEMSQLMLKEPTHCEANPDLIFEDMEVMTDFELHVLCKQYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKMANHPLLHRQYYTAEKLKEMSQLMLKEPTHCEANPDLIFEDMEVMTDFELHVLCKQYR 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 HINNFQLDMDLILDSGKFRVLGCILSELKQKGDRVVLFSQFTMMLDILEVLLKHHQHRYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HINNFQLDMDLILDSGKFRVLGCILSELKQKGDRVVLFSQFTMMLDILEVLLKHHQHRYL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 RLDGKTQISERIHLIDEFNTDMDIFVFLLSTKAGGLGINLTSANVVILHDIDCNPYNDKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLDGKTQISERIHLIDEFNTDMDIFVFLLSTKAGGLGINLTSANVVILHDIDCNPYNDKQ 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 AEDRCHRVGQTKEVLVIKLISQGTIEESMLKINQQKLKLEQDMTTVDEGDEGSMPADIAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AEDRCHRVGQTKEVLVIKLISQGTIEESMLKINQQKLKLEQDMTTVDEGDEGSMPADIAT 970 980 990 1000 1010 1020 pF1KA1 LLKTSMGL :::::::: NP_001 LLKTSMGL >>XP_016863952 (OMIM: 136000,612761) PREDICTED: SWI/SNF- (1026 aa) initn: 6689 init1: 4987 opt: 6689 Z-score: 5679.1 bits: 1062.4 E(85289): 0 Smith-Waterman score: 6689; 99.8% identity (99.8% similar) in 1028 aa overlap (1-1028:1-1026) 10 20 30 40 50 60 pF1KA1 MNLFNLDRFRFEKRNKIEEAPEATPQPSQPGPSSPISLSAEEENAEGEVSRANTPDSDIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNLFNLDRFRFEKRNKIEEAPEATPQPSQPGPSSPISLSAEEENAEGEVSRANTPDSDIT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 EKTEDSSVPETPDNERKASISYFKNQRGIQYIDLSSDSEDVVSPNCSNTVQEKTFNKDTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKTEDSSVPETPDNERKASISYFKNQRGIQYIDLSSDSEDVVSPNCSNTVQEKTFNKDTV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 IIVSEPSEDEESQGLPTMARRNDDISELEDLSELEDLKDAKLQTLKELFPQRSDNDLLKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IIVSEPSEDEESQGLPTMARRNDDISELEDLSELEDLKDAKLQTLKELFPQRSDNDLLKL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 IESTSTMDGAIAAALLMFGDAGGGPRKRKLSSSSEPYEEDEFNDDQSIKKTRLDHGEESN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IESTSTMDGAIAAALLMFGDAGGGPRKRKLSSSSEPYEEDEFNDDQSIKKTRLDHGEESN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 ESAESSSNWEKQESIVLKLQKEFPNFDKQELREVLKEHEWMYTEALESLKVFAEDQDMQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESAESSSNWEKQESIVLKLQKEFPNFDKQELREVLKEHEWMYTEALESLKVFAEDQDMQY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 VSQSEVPNGKEVSSRSQNYPKNATKTKLKQKFSMKAQNGFNKKRKKNVFNPKRVVEDSEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VSQSEVPNGKEVSSRSQNYPKNATKTKLKQKFSMKAQNGFNKKRKKNVFNPKRVVEDSEY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 DSGSDVGSSLDEDYSSGEEVMEDGYKGKILHFLQDASIGELTLIPQCSQKKAQKITELRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DSGSDVGSSLDEDYSSGEEVMEDGYKGKILHFLQDASIGELTLIPQCSQKKAQKITELRP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 FNSWEALFTKMSKTNGLSEDLIWHCKTLIQERDVVIRLMNKCEDISNKLTKQVTMLTGNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FNSWEALFTKMSKTNGLSEDLIWHCKTLIQERDVVIRLMNKCEDISNKLTKQVTMLTGNG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 GGWNIEQPSILNQSLSLKPYQKVGLNWLALVHKHGLNGILADEMGLGKTIQAIAFLAYLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GGWNIEQPSILNQSLSLKPYQKVGLNWLALVHKHGLNGILADEMGLGKTIQAIAFLAYLY 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 QEGNNGPHLIVVPASTIDNWLREVNLWCPTLKVLCYYGSQEERKQIRFNIHSRYEDYNVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QEGNNGPHLIVVPASTIDNWLREVNLWCPTLKVLCYYGSQEERKQIRFNIHSRYEDYNVI 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 VTTYNCAISSSDDRSLFRRLKLNYAIFDEGHMLKNMGSIRYQHLMTINANNRLLLTGTPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VTTYNCAISSSDDRSLFRRLKLNYAIFDEGHMLKNMGSIRYQHLMTINANNRLLLTGTPV 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 QNNLLELMSLLNFVMPHMFSSSTSEIRRMFSSKTKSADEQSIYEKERIAHAKQIIKPFIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QNNLLELMSLLNFVMPHMFSSSTSEIRRMFSSKTKSADEQSIYEKERIAHAKQIIKPFIL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 RRVKEEVLKQLPPKKDRIELCAMSEKQEQLYLGLFNRLKKSINNLVTEKNTEMCNVMMQL ::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::: XP_016 RRVKEEVLKQLPPKKDRIELCAMSEKQEQLYLGLFNRLKKSINNL--EKNTEMCNVMMQL 730 740 750 760 770 790 800 810 820 830 840 pF1KA1 RKMANHPLLHRQYYTAEKLKEMSQLMLKEPTHCEANPDLIFEDMEVMTDFELHVLCKQYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RKMANHPLLHRQYYTAEKLKEMSQLMLKEPTHCEANPDLIFEDMEVMTDFELHVLCKQYR 780 790 800 810 820 830 850 860 870 880 890 900 pF1KA1 HINNFQLDMDLILDSGKFRVLGCILSELKQKGDRVVLFSQFTMMLDILEVLLKHHQHRYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HINNFQLDMDLILDSGKFRVLGCILSELKQKGDRVVLFSQFTMMLDILEVLLKHHQHRYL 840 850 860 870 880 890 910 920 930 940 950 960 pF1KA1 RLDGKTQISERIHLIDEFNTDMDIFVFLLSTKAGGLGINLTSANVVILHDIDCNPYNDKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLDGKTQISERIHLIDEFNTDMDIFVFLLSTKAGGLGINLTSANVVILHDIDCNPYNDKQ 900 910 920 930 940 950 970 980 990 1000 1010 1020 pF1KA1 AEDRCHRVGQTKEVLVIKLISQGTIEESMLKINQQKLKLEQDMTTVDEGDEGSMPADIAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AEDRCHRVGQTKEVLVIKLISQGTIEESMLKINQQKLKLEQDMTTVDEGDEGSMPADIAT 960 970 980 990 1000 1010 pF1KA1 LLKTSMGL :::::::: XP_016 LLKTSMGL 1020 >>NP_064544 (OMIM: 136000,612761) SWI/SNF-related matrix (1026 aa) initn: 6689 init1: 4987 opt: 6689 Z-score: 5679.1 bits: 1062.4 E(85289): 0 Smith-Waterman score: 6689; 99.8% identity (99.8% similar) in 1028 aa overlap (1-1028:1-1026) 10 20 30 40 50 60 pF1KA1 MNLFNLDRFRFEKRNKIEEAPEATPQPSQPGPSSPISLSAEEENAEGEVSRANTPDSDIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_064 MNLFNLDRFRFEKRNKIEEAPEATPQPSQPGPSSPISLSAEEENAEGEVSRANTPDSDIT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 EKTEDSSVPETPDNERKASISYFKNQRGIQYIDLSSDSEDVVSPNCSNTVQEKTFNKDTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_064 EKTEDSSVPETPDNERKASISYFKNQRGIQYIDLSSDSEDVVSPNCSNTVQEKTFNKDTV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 IIVSEPSEDEESQGLPTMARRNDDISELEDLSELEDLKDAKLQTLKELFPQRSDNDLLKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_064 IIVSEPSEDEESQGLPTMARRNDDISELEDLSELEDLKDAKLQTLKELFPQRSDNDLLKL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 IESTSTMDGAIAAALLMFGDAGGGPRKRKLSSSSEPYEEDEFNDDQSIKKTRLDHGEESN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_064 IESTSTMDGAIAAALLMFGDAGGGPRKRKLSSSSEPYEEDEFNDDQSIKKTRLDHGEESN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 ESAESSSNWEKQESIVLKLQKEFPNFDKQELREVLKEHEWMYTEALESLKVFAEDQDMQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_064 ESAESSSNWEKQESIVLKLQKEFPNFDKQELREVLKEHEWMYTEALESLKVFAEDQDMQY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 VSQSEVPNGKEVSSRSQNYPKNATKTKLKQKFSMKAQNGFNKKRKKNVFNPKRVVEDSEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_064 VSQSEVPNGKEVSSRSQNYPKNATKTKLKQKFSMKAQNGFNKKRKKNVFNPKRVVEDSEY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 DSGSDVGSSLDEDYSSGEEVMEDGYKGKILHFLQDASIGELTLIPQCSQKKAQKITELRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_064 DSGSDVGSSLDEDYSSGEEVMEDGYKGKILHFLQDASIGELTLIPQCSQKKAQKITELRP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 FNSWEALFTKMSKTNGLSEDLIWHCKTLIQERDVVIRLMNKCEDISNKLTKQVTMLTGNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_064 FNSWEALFTKMSKTNGLSEDLIWHCKTLIQERDVVIRLMNKCEDISNKLTKQVTMLTGNG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 GGWNIEQPSILNQSLSLKPYQKVGLNWLALVHKHGLNGILADEMGLGKTIQAIAFLAYLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_064 GGWNIEQPSILNQSLSLKPYQKVGLNWLALVHKHGLNGILADEMGLGKTIQAIAFLAYLY 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 QEGNNGPHLIVVPASTIDNWLREVNLWCPTLKVLCYYGSQEERKQIRFNIHSRYEDYNVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_064 QEGNNGPHLIVVPASTIDNWLREVNLWCPTLKVLCYYGSQEERKQIRFNIHSRYEDYNVI 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 VTTYNCAISSSDDRSLFRRLKLNYAIFDEGHMLKNMGSIRYQHLMTINANNRLLLTGTPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_064 VTTYNCAISSSDDRSLFRRLKLNYAIFDEGHMLKNMGSIRYQHLMTINANNRLLLTGTPV 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 QNNLLELMSLLNFVMPHMFSSSTSEIRRMFSSKTKSADEQSIYEKERIAHAKQIIKPFIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_064 QNNLLELMSLLNFVMPHMFSSSTSEIRRMFSSKTKSADEQSIYEKERIAHAKQIIKPFIL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 RRVKEEVLKQLPPKKDRIELCAMSEKQEQLYLGLFNRLKKSINNLVTEKNTEMCNVMMQL ::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::: NP_064 RRVKEEVLKQLPPKKDRIELCAMSEKQEQLYLGLFNRLKKSINNL--EKNTEMCNVMMQL 730 740 750 760 770 790 800 810 820 830 840 pF1KA1 RKMANHPLLHRQYYTAEKLKEMSQLMLKEPTHCEANPDLIFEDMEVMTDFELHVLCKQYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_064 RKMANHPLLHRQYYTAEKLKEMSQLMLKEPTHCEANPDLIFEDMEVMTDFELHVLCKQYR 780 790 800 810 820 830 850 860 870 880 890 900 pF1KA1 HINNFQLDMDLILDSGKFRVLGCILSELKQKGDRVVLFSQFTMMLDILEVLLKHHQHRYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_064 HINNFQLDMDLILDSGKFRVLGCILSELKQKGDRVVLFSQFTMMLDILEVLLKHHQHRYL 840 850 860 870 880 890 910 920 930 940 950 960 pF1KA1 RLDGKTQISERIHLIDEFNTDMDIFVFLLSTKAGGLGINLTSANVVILHDIDCNPYNDKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_064 RLDGKTQISERIHLIDEFNTDMDIFVFLLSTKAGGLGINLTSANVVILHDIDCNPYNDKQ 900 910 920 930 940 950 970 980 990 1000 1010 1020 pF1KA1 AEDRCHRVGQTKEVLVIKLISQGTIEESMLKINQQKLKLEQDMTTVDEGDEGSMPADIAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_064 AEDRCHRVGQTKEVLVIKLISQGTIEESMLKINQQKLKLEQDMTTVDEGDEGSMPADIAT 960 970 980 990 1000 1010 pF1KA1 LLKTSMGL :::::::: NP_064 LLKTSMGL 1020 >>NP_001241878 (OMIM: 136000,612761) SWI/SNF-related mat (596 aa) initn: 3907 init1: 2205 opt: 3907 Z-score: 3323.0 bits: 625.7 E(85289): 2.4e-178 Smith-Waterman score: 3907; 99.7% identity (99.7% similar) in 598 aa overlap (431-1028:1-596) 410 420 430 440 450 460 pF1KA1 LTLIPQCSQKKAQKITELRPFNSWEALFTKMSKTNGLSEDLIWHCKTLIQERDVVIRLMN :::::::::::::::::::::::::::::: NP_001 MSKTNGLSEDLIWHCKTLIQERDVVIRLMN 10 20 30 470 480 490 500 510 520 pF1KA1 KCEDISNKLTKQVTMLTGNGGGWNIEQPSILNQSLSLKPYQKVGLNWLALVHKHGLNGIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KCEDISNKLTKQVTMLTGNGGGWNIEQPSILNQSLSLKPYQKVGLNWLALVHKHGLNGIL 40 50 60 70 80 90 530 540 550 560 570 580 pF1KA1 ADEMGLGKTIQAIAFLAYLYQEGNNGPHLIVVPASTIDNWLREVNLWCPTLKVLCYYGSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ADEMGLGKTIQAIAFLAYLYQEGNNGPHLIVVPASTIDNWLREVNLWCPTLKVLCYYGSQ 100 110 120 130 140 150 590 600 610 620 630 640 pF1KA1 EERKQIRFNIHSRYEDYNVIVTTYNCAISSSDDRSLFRRLKLNYAIFDEGHMLKNMGSIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EERKQIRFNIHSRYEDYNVIVTTYNCAISSSDDRSLFRRLKLNYAIFDEGHMLKNMGSIR 160 170 180 190 200 210 650 660 670 680 690 700 pF1KA1 YQHLMTINANNRLLLTGTPVQNNLLELMSLLNFVMPHMFSSSTSEIRRMFSSKTKSADEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YQHLMTINANNRLLLTGTPVQNNLLELMSLLNFVMPHMFSSSTSEIRRMFSSKTKSADEQ 220 230 240 250 260 270 710 720 730 740 750 760 pF1KA1 SIYEKERIAHAKQIIKPFILRRVKEEVLKQLPPKKDRIELCAMSEKQEQLYLGLFNRLKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SIYEKERIAHAKQIIKPFILRRVKEEVLKQLPPKKDRIELCAMSEKQEQLYLGLFNRLKK 280 290 300 310 320 330 770 780 790 800 810 820 pF1KA1 SINNLVTEKNTEMCNVMMQLRKMANHPLLHRQYYTAEKLKEMSQLMLKEPTHCEANPDLI ::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SINNL--EKNTEMCNVMMQLRKMANHPLLHRQYYTAEKLKEMSQLMLKEPTHCEANPDLI 340 350 360 370 380 830 840 850 860 870 880 pF1KA1 FEDMEVMTDFELHVLCKQYRHINNFQLDMDLILDSGKFRVLGCILSELKQKGDRVVLFSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FEDMEVMTDFELHVLCKQYRHINNFQLDMDLILDSGKFRVLGCILSELKQKGDRVVLFSQ 390 400 410 420 430 440 890 900 910 920 930 940 pF1KA1 FTMMLDILEVLLKHHQHRYLRLDGKTQISERIHLIDEFNTDMDIFVFLLSTKAGGLGINL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FTMMLDILEVLLKHHQHRYLRLDGKTQISERIHLIDEFNTDMDIFVFLLSTKAGGLGINL 450 460 470 480 490 500 950 960 970 980 990 1000 pF1KA1 TSANVVILHDIDCNPYNDKQAEDRCHRVGQTKEVLVIKLISQGTIEESMLKINQQKLKLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSANVVILHDIDCNPYNDKQAEDRCHRVGQTKEVLVIKLISQGTIEESMLKINQQKLKLE 510 520 530 540 550 560 1010 1020 pF1KA1 QDMTTVDEGDEGSMPADIATLLKTSMGL :::::::::::::::::::::::::::: NP_001 QDMTTVDEGDEGSMPADIATLLKTSMGL 570 580 590 >>XP_016863954 (OMIM: 136000,612761) PREDICTED: SWI/SNF- (505 aa) initn: 3307 init1: 3307 opt: 3307 Z-score: 2815.1 bits: 531.5 E(85289): 4.6e-150 Smith-Waterman score: 3307; 100.0% identity (100.0% similar) in 505 aa overlap (524-1028:1-505) 500 510 520 530 540 550 pF1KA1 SLSLKPYQKVGLNWLALVHKHGLNGILADEMGLGKTIQAIAFLAYLYQEGNNGPHLIVVP :::::::::::::::::::::::::::::: XP_016 MGLGKTIQAIAFLAYLYQEGNNGPHLIVVP 10 20 30 560 570 580 590 600 610 pF1KA1 ASTIDNWLREVNLWCPTLKVLCYYGSQEERKQIRFNIHSRYEDYNVIVTTYNCAISSSDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASTIDNWLREVNLWCPTLKVLCYYGSQEERKQIRFNIHSRYEDYNVIVTTYNCAISSSDD 40 50 60 70 80 90 620 630 640 650 660 670 pF1KA1 RSLFRRLKLNYAIFDEGHMLKNMGSIRYQHLMTINANNRLLLTGTPVQNNLLELMSLLNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RSLFRRLKLNYAIFDEGHMLKNMGSIRYQHLMTINANNRLLLTGTPVQNNLLELMSLLNF 100 110 120 130 140 150 680 690 700 710 720 730 pF1KA1 VMPHMFSSSTSEIRRMFSSKTKSADEQSIYEKERIAHAKQIIKPFILRRVKEEVLKQLPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VMPHMFSSSTSEIRRMFSSKTKSADEQSIYEKERIAHAKQIIKPFILRRVKEEVLKQLPP 160 170 180 190 200 210 740 750 760 770 780 790 pF1KA1 KKDRIELCAMSEKQEQLYLGLFNRLKKSINNLVTEKNTEMCNVMMQLRKMANHPLLHRQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKDRIELCAMSEKQEQLYLGLFNRLKKSINNLVTEKNTEMCNVMMQLRKMANHPLLHRQY 220 230 240 250 260 270 800 810 820 830 840 850 pF1KA1 YTAEKLKEMSQLMLKEPTHCEANPDLIFEDMEVMTDFELHVLCKQYRHINNFQLDMDLIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YTAEKLKEMSQLMLKEPTHCEANPDLIFEDMEVMTDFELHVLCKQYRHINNFQLDMDLIL 280 290 300 310 320 330 860 870 880 890 900 910 pF1KA1 DSGKFRVLGCILSELKQKGDRVVLFSQFTMMLDILEVLLKHHQHRYLRLDGKTQISERIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DSGKFRVLGCILSELKQKGDRVVLFSQFTMMLDILEVLLKHHQHRYLRLDGKTQISERIH 340 350 360 370 380 390 920 930 940 950 960 970 pF1KA1 LIDEFNTDMDIFVFLLSTKAGGLGINLTSANVVILHDIDCNPYNDKQAEDRCHRVGQTKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LIDEFNTDMDIFVFLLSTKAGGLGINLTSANVVILHDIDCNPYNDKQAEDRCHRVGQTKE 400 410 420 430 440 450 980 990 1000 1010 1020 pF1KA1 VLVIKLISQGTIEESMLKINQQKLKLEQDMTTVDEGDEGSMPADIATLLKTSMGL ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLVIKLISQGTIEESMLKINQQKLKLEQDMTTVDEGDEGSMPADIATLLKTSMGL 460 470 480 490 500 >>XP_016863953 (OMIM: 136000,612761) PREDICTED: SWI/SNF- (505 aa) initn: 3307 init1: 3307 opt: 3307 Z-score: 2815.1 bits: 531.5 E(85289): 4.6e-150 Smith-Waterman score: 3307; 100.0% identity (100.0% similar) in 505 aa overlap (524-1028:1-505) 500 510 520 530 540 550 pF1KA1 SLSLKPYQKVGLNWLALVHKHGLNGILADEMGLGKTIQAIAFLAYLYQEGNNGPHLIVVP :::::::::::::::::::::::::::::: XP_016 MGLGKTIQAIAFLAYLYQEGNNGPHLIVVP 10 20 30 560 570 580 590 600 610 pF1KA1 ASTIDNWLREVNLWCPTLKVLCYYGSQEERKQIRFNIHSRYEDYNVIVTTYNCAISSSDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASTIDNWLREVNLWCPTLKVLCYYGSQEERKQIRFNIHSRYEDYNVIVTTYNCAISSSDD 40 50 60 70 80 90 620 630 640 650 660 670 pF1KA1 RSLFRRLKLNYAIFDEGHMLKNMGSIRYQHLMTINANNRLLLTGTPVQNNLLELMSLLNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RSLFRRLKLNYAIFDEGHMLKNMGSIRYQHLMTINANNRLLLTGTPVQNNLLELMSLLNF 100 110 120 130 140 150 680 690 700 710 720 730 pF1KA1 VMPHMFSSSTSEIRRMFSSKTKSADEQSIYEKERIAHAKQIIKPFILRRVKEEVLKQLPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VMPHMFSSSTSEIRRMFSSKTKSADEQSIYEKERIAHAKQIIKPFILRRVKEEVLKQLPP 160 170 180 190 200 210 740 750 760 770 780 790 pF1KA1 KKDRIELCAMSEKQEQLYLGLFNRLKKSINNLVTEKNTEMCNVMMQLRKMANHPLLHRQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKDRIELCAMSEKQEQLYLGLFNRLKKSINNLVTEKNTEMCNVMMQLRKMANHPLLHRQY 220 230 240 250 260 270 800 810 820 830 840 850 pF1KA1 YTAEKLKEMSQLMLKEPTHCEANPDLIFEDMEVMTDFELHVLCKQYRHINNFQLDMDLIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YTAEKLKEMSQLMLKEPTHCEANPDLIFEDMEVMTDFELHVLCKQYRHINNFQLDMDLIL 280 290 300 310 320 330 860 870 880 890 900 910 pF1KA1 DSGKFRVLGCILSELKQKGDRVVLFSQFTMMLDILEVLLKHHQHRYLRLDGKTQISERIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DSGKFRVLGCILSELKQKGDRVVLFSQFTMMLDILEVLLKHHQHRYLRLDGKTQISERIH 340 350 360 370 380 390 920 930 940 950 960 970 pF1KA1 LIDEFNTDMDIFVFLLSTKAGGLGINLTSANVVILHDIDCNPYNDKQAEDRCHRVGQTKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LIDEFNTDMDIFVFLLSTKAGGLGINLTSANVVILHDIDCNPYNDKQAEDRCHRVGQTKE 400 410 420 430 440 450 980 990 1000 1010 1020 pF1KA1 VLVIKLISQGTIEESMLKINQQKLKLEQDMTTVDEGDEGSMPADIATLLKTSMGL ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLVIKLISQGTIEESMLKINQQKLKLEQDMTTVDEGDEGSMPADIATLLKTSMGL 460 470 480 490 500 >>XP_016872368 (OMIM: 605191) PREDICTED: TATA-binding pr (1519 aa) initn: 839 init1: 305 opt: 874 Z-score: 745.0 bits: 150.0 E(85289): 9.3e-35 Smith-Waterman score: 874; 33.9% identity (61.8% similar) in 558 aa overlap (484-1017:925-1462) 460 470 480 490 500 510 pF1KA1 VVIRLMNKCEDISNKLTKQVTMLTGNGGGWNIEQPSILNQSLSLKPYQKVGLNWLALVHK : . : .: : . ::. :.::::...: XP_016 DPPNMSAELIQLKAKERHFLEQLLDGKKLENYKIPVPINAEL--RKYQQDGVNWLAFLNK 900 910 920 930 940 950 520 530 540 550 560 pF1KA1 HGLNGILADEMGLGKTIQAIAFLA----YLYQEGNNG--------PHLIVVPASTIDNWL . :.::: :.::::::.:.: .:: . :: . : :.: : . .:. XP_016 YKLHGILCDDMGLGKTLQSICILAGDHCHRAQEYARSKLAECMPLPSLVVCPPTLTGHWV 960 970 980 990 1000 1010 570 580 590 600 610 pF1KA1 REVNLWCPT--LKVLCYYGSQEERKQIRFNIHSRYEDYNVIVTTYNCAISSSDDRSLFRR ::. .: :. : : : :: ... .. . .:.::..:. . .: ..:: XP_016 DEVGKFCSREYLNPLHYTGPPTERIRLQHQV----KRHNLIVASYDVV---RNDIDFFRN 1020 1030 1040 1050 1060 620 630 640 650 660 670 pF1KA1 LKLNYAIFDEGHMLKNMGSIRYQHLMTINANNRLLLTGTPVQNNLLELMSLLNFVMPHMF .:.:: :.::::..:: . . . ..:: :..:.:::.:::.::: ::..:.:: .. XP_016 IKFNYCILDEGHVIKNGKTKLSKAVKQLTANYRIILSGTPIQNNVLELWSLFDFLMPGFL 1070 1080 1090 1100 1110 1120 680 690 700 710 720 730 pF1KA1 SSSTSEIRRMFSSKTKSADEQSIYEKERI------AHAKQIIKPFILRRVKEEVLKQLPP .. . :. . : : .: .... : .:.. ::.:::.::.::..::: XP_016 GTERQFAARYGKPILASRDARSSSREQEAGVLAMDALHRQVL-PFLLRRMKEDVLQDLPP 1130 1140 1150 1160 1170 1180 740 750 760 770 780 790 pF1KA1 KKDRIELCAMSEKQEQLYLGLF-NRLKKSINNLVTEKNTEMCNVMMQLRKMANHPLLHRQ : . :..: : ::: . .: : .... :. . . .: : ..: . : XP_016 KIIQDYYCTLSPLQVQLYEDFAKSRAKCDVDETVSSATLSEETEKPKL-KATGHVFQALQ 1190 1200 1210 1220 1230 1240 800 810 820 830 840 850 pF1KA1 YYTAEKLKEMSQLMLKEPTHCEANPDLIFEDMEVMTDFELHVLCKQYRHINNFQLDMDLI : .:: . :.: : : : . : . :... :: . . . :: .: XP_016 YL--RKLCNHPALVLT-PQHPEFKTTA--EKLAVQNS-SLHDIQHAPKLSALKQLLLDCG 1250 1260 1270 1280 1290 860 870 880 890 900 pF1KA1 LDSGKFRVLGCILSELKQKGDRVVLFSQFTMMLDILEV-LLKHHQHR--YLRLDGKTQIS : .:. : .: :...: :. ::::.: ::: : ::::::. . XP_016 LGNGSTSESG---TESVVAQHRILIFCQLKSMLDIVEHDLLKPHLPSVTYLRLDGSIPPG 1300 1310 1320 1330 1340 1350 910 920 930 940 950 960 pF1KA1 ERIHLIDEFNTDMDIFVFLLSTKAGGLGINLTSANVVILHDIDCNPYNDKQAEDRCHRVG .: ....::.: .: :.::.:..::::.:::.:..:.. . : ::. : :: :: ::.: XP_016 QRHSIVSRFNNDPSIDVLLLTTHVGGLGLNLTGADTVVFVEHDWNPMRDLQAMDRAHRIG 1360 1370 1380 1390 1400 1410 970 980 990 1000 1010 1020 pF1KA1 QTKEVLVIKLISQGTIEESMLKINQQKLKLEQDMTTVDEGDEGSMPADIATLLKTSMGL : . : : .::..::.::... ... :... . . . .... :: .: XP_016 QKRVVNVYRLITRGTLEEKIMGLQKFKMNIANTVISQENSSLQSMGTDQLLDLFTLDKDG 1420 1430 1440 1450 1460 1470 XP_016 KAEKADTSTSGKASMKSILENLSDLWDQEQYDSEYSLENFMHSLK 1480 1490 1500 1510 >>XP_016872370 (OMIM: 605191) PREDICTED: TATA-binding pr (1519 aa) initn: 839 init1: 305 opt: 874 Z-score: 745.0 bits: 150.0 E(85289): 9.3e-35 Smith-Waterman score: 874; 33.9% identity (61.8% similar) in 558 aa overlap (484-1017:925-1462) 460 470 480 490 500 510 pF1KA1 VVIRLMNKCEDISNKLTKQVTMLTGNGGGWNIEQPSILNQSLSLKPYQKVGLNWLALVHK : . : .: : . ::. :.::::...: XP_016 DPPNMSAELIQLKAKERHFLEQLLDGKKLENYKIPVPINAEL--RKYQQDGVNWLAFLNK 900 910 920 930 940 950 520 530 540 550 560 pF1KA1 HGLNGILADEMGLGKTIQAIAFLA----YLYQEGNNG--------PHLIVVPASTIDNWL . :.::: :.::::::.:.: .:: . :: . : :.: : . .:. XP_016 YKLHGILCDDMGLGKTLQSICILAGDHCHRAQEYARSKLAECMPLPSLVVCPPTLTGHWV 960 970 980 990 1000 1010 570 580 590 600 610 pF1KA1 REVNLWCPT--LKVLCYYGSQEERKQIRFNIHSRYEDYNVIVTTYNCAISSSDDRSLFRR ::. .: :. : : : :: ... .. . .:.::..:. . .: ..:: XP_016 DEVGKFCSREYLNPLHYTGPPTERIRLQHQV----KRHNLIVASYDVV---RNDIDFFRN 1020 1030 1040 1050 1060 620 630 640 650 660 670 pF1KA1 LKLNYAIFDEGHMLKNMGSIRYQHLMTINANNRLLLTGTPVQNNLLELMSLLNFVMPHMF .:.:: :.::::..:: . . . ..:: :..:.:::.:::.::: ::..:.:: .. XP_016 IKFNYCILDEGHVIKNGKTKLSKAVKQLTANYRIILSGTPIQNNVLELWSLFDFLMPGFL 1070 1080 1090 1100 1110 1120 680 690 700 710 720 730 pF1KA1 SSSTSEIRRMFSSKTKSADEQSIYEKERI------AHAKQIIKPFILRRVKEEVLKQLPP .. . :. . : : .: .... : .:.. ::.:::.::.::..::: XP_016 GTERQFAARYGKPILASRDARSSSREQEAGVLAMDALHRQVL-PFLLRRMKEDVLQDLPP 1130 1140 1150 1160 1170 1180 740 750 760 770 780 790 pF1KA1 KKDRIELCAMSEKQEQLYLGLF-NRLKKSINNLVTEKNTEMCNVMMQLRKMANHPLLHRQ : . :..: : ::: . .: : .... :. . . .: : ..: . : XP_016 KIIQDYYCTLSPLQVQLYEDFAKSRAKCDVDETVSSATLSEETEKPKL-KATGHVFQALQ 1190 1200 1210 1220 1230 1240 800 810 820 830 840 850 pF1KA1 YYTAEKLKEMSQLMLKEPTHCEANPDLIFEDMEVMTDFELHVLCKQYRHINNFQLDMDLI : .:: . :.: : : : . : . :... :: . . . :: .: XP_016 YL--RKLCNHPALVLT-PQHPEFKTTA--EKLAVQNS-SLHDIQHAPKLSALKQLLLDCG 1250 1260 1270 1280 1290 860 870 880 890 900 pF1KA1 LDSGKFRVLGCILSELKQKGDRVVLFSQFTMMLDILEV-LLKHHQHR--YLRLDGKTQIS : .:. : .: :...: :. ::::.: ::: : ::::::. . XP_016 LGNGSTSESG---TESVVAQHRILIFCQLKSMLDIVEHDLLKPHLPSVTYLRLDGSIPPG 1300 1310 1320 1330 1340 1350 910 920 930 940 950 960 pF1KA1 ERIHLIDEFNTDMDIFVFLLSTKAGGLGINLTSANVVILHDIDCNPYNDKQAEDRCHRVG .: ....::.: .: :.::.:..::::.:::.:..:.. . : ::. : :: :: ::.: XP_016 QRHSIVSRFNNDPSIDVLLLTTHVGGLGLNLTGADTVVFVEHDWNPMRDLQAMDRAHRIG 1360 1370 1380 1390 1400 1410 970 980 990 1000 1010 1020 pF1KA1 QTKEVLVIKLISQGTIEESMLKINQQKLKLEQDMTTVDEGDEGSMPADIATLLKTSMGL : . : : .::..::.::... ... :... . . . .... :: .: XP_016 QKRVVNVYRLITRGTLEEKIMGLQKFKMNIANTVISQENSSLQSMGTDQLLDLFTLDKDG 1420 1430 1440 1450 1460 1470 XP_016 KAEKADTSTSGKASMKSILENLSDLWDQEQYDSEYSLENFMHSLK 1480 1490 1500 1510 >>XP_016872369 (OMIM: 605191) PREDICTED: TATA-binding pr (1519 aa) initn: 839 init1: 305 opt: 874 Z-score: 745.0 bits: 150.0 E(85289): 9.3e-35 Smith-Waterman score: 874; 33.9% identity (61.8% similar) in 558 aa overlap (484-1017:925-1462) 460 470 480 490 500 510 pF1KA1 VVIRLMNKCEDISNKLTKQVTMLTGNGGGWNIEQPSILNQSLSLKPYQKVGLNWLALVHK : . : .: : . ::. :.::::...: XP_016 DPPNMSAELIQLKAKERHFLEQLLDGKKLENYKIPVPINAEL--RKYQQDGVNWLAFLNK 900 910 920 930 940 950 520 530 540 550 560 pF1KA1 HGLNGILADEMGLGKTIQAIAFLA----YLYQEGNNG--------PHLIVVPASTIDNWL . :.::: :.::::::.:.: .:: . :: . : :.: : . .:. XP_016 YKLHGILCDDMGLGKTLQSICILAGDHCHRAQEYARSKLAECMPLPSLVVCPPTLTGHWV 960 970 980 990 1000 1010 570 580 590 600 610 pF1KA1 REVNLWCPT--LKVLCYYGSQEERKQIRFNIHSRYEDYNVIVTTYNCAISSSDDRSLFRR ::. .: :. : : : :: ... .. . .:.::..:. . .: ..:: XP_016 DEVGKFCSREYLNPLHYTGPPTERIRLQHQV----KRHNLIVASYDVV---RNDIDFFRN 1020 1030 1040 1050 1060 620 630 640 650 660 670 pF1KA1 LKLNYAIFDEGHMLKNMGSIRYQHLMTINANNRLLLTGTPVQNNLLELMSLLNFVMPHMF .:.:: :.::::..:: . . . ..:: :..:.:::.:::.::: ::..:.:: .. XP_016 IKFNYCILDEGHVIKNGKTKLSKAVKQLTANYRIILSGTPIQNNVLELWSLFDFLMPGFL 1070 1080 1090 1100 1110 1120 680 690 700 710 720 730 pF1KA1 SSSTSEIRRMFSSKTKSADEQSIYEKERI------AHAKQIIKPFILRRVKEEVLKQLPP .. . :. . : : .: .... : .:.. ::.:::.::.::..::: XP_016 GTERQFAARYGKPILASRDARSSSREQEAGVLAMDALHRQVL-PFLLRRMKEDVLQDLPP 1130 1140 1150 1160 1170 1180 740 750 760 770 780 790 pF1KA1 KKDRIELCAMSEKQEQLYLGLF-NRLKKSINNLVTEKNTEMCNVMMQLRKMANHPLLHRQ : . :..: : ::: . .: : .... :. . . .: : ..: . : XP_016 KIIQDYYCTLSPLQVQLYEDFAKSRAKCDVDETVSSATLSEETEKPKL-KATGHVFQALQ 1190 1200 1210 1220 1230 1240 800 810 820 830 840 850 pF1KA1 YYTAEKLKEMSQLMLKEPTHCEANPDLIFEDMEVMTDFELHVLCKQYRHINNFQLDMDLI : .:: . :.: : : : . : . :... :: . . . :: .: XP_016 YL--RKLCNHPALVLT-PQHPEFKTTA--EKLAVQNS-SLHDIQHAPKLSALKQLLLDCG 1250 1260 1270 1280 1290 860 870 880 890 900 pF1KA1 LDSGKFRVLGCILSELKQKGDRVVLFSQFTMMLDILEV-LLKHHQHR--YLRLDGKTQIS : .:. : .: :...: :. ::::.: ::: : ::::::. . XP_016 LGNGSTSESG---TESVVAQHRILIFCQLKSMLDIVEHDLLKPHLPSVTYLRLDGSIPPG 1300 1310 1320 1330 1340 1350 910 920 930 940 950 960 pF1KA1 ERIHLIDEFNTDMDIFVFLLSTKAGGLGINLTSANVVILHDIDCNPYNDKQAEDRCHRVG .: ....::.: .: :.::.:..::::.:::.:..:.. . : ::. : :: :: ::.: XP_016 QRHSIVSRFNNDPSIDVLLLTTHVGGLGLNLTGADTVVFVEHDWNPMRDLQAMDRAHRIG 1360 1370 1380 1390 1400 1410 970 980 990 1000 1010 1020 pF1KA1 QTKEVLVIKLISQGTIEESMLKINQQKLKLEQDMTTVDEGDEGSMPADIATLLKTSMGL : . : : .::..::.::... ... :... . . . .... :: .: XP_016 QKRVVNVYRLITRGTLEEKIMGLQKFKMNIANTVISQENSSLQSMGTDQLLDLFTLDKDG 1420 1430 1440 1450 1460 1470 XP_016 KAEKADTSTSGKASMKSILENLSDLWDQEQYDSEYSLENFMHSLK 1480 1490 1500 1510 1028 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 10:49:33 2016 done: Thu Nov 3 10:49:35 2016 Total Scan time: 12.060 Total Display time: 0.290 Function used was FASTA [36.3.4 Apr, 2011]