FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1128, 1047 aa 1>>>pF1KA1128 1047 - 1047 aa - 1047 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.8925+/-0.00108; mu= 5.1924+/- 0.065 mean_var=162.7091+/-33.528, 0's: 0 Z-trim(109.6): 23 B-trim: 300 in 1/49 Lambda= 0.100547 statistics sampled from 10958 (10973) to 10958 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.683), E-opt: 0.2 (0.337), width: 16 Scan time: 3.900 The best scores are: opt bits E(32554) CCDS60582.1 CCSER2 gene_id:54462|Hs108|chr10 (1047) 7051 1035.5 0 CCDS31235.1 CCSER2 gene_id:54462|Hs108|chr10 ( 834) 5258 775.4 0 CCDS73159.1 CCSER2 gene_id:54462|Hs108|chr10 ( 567) 3551 527.8 2.6e-149 CCDS60583.1 CCSER2 gene_id:54462|Hs108|chr10 ( 261) 1464 224.9 1.8e-58 >>CCDS60582.1 CCSER2 gene_id:54462|Hs108|chr10 (1047 aa) initn: 7051 init1: 7051 opt: 7051 Z-score: 5533.6 bits: 1035.5 E(32554): 0 Smith-Waterman score: 7051; 100.0% identity (100.0% similar) in 1047 aa overlap (1-1047:1-1047) 10 20 30 40 50 60 pF1KA1 MEEKTQIKTFLGSKLPKYGTKSVRSTLQPMPNGTPVNLLGTSKNSNVKSYIKNNGSDCPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 MEEKTQIKTFLGSKLPKYGTKSVRSTLQPMPNGTPVNLLGTSKNSNVKSYIKNNGSDCPS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 SHSFNWRKANKYQLCAQGVEEPNNTQNSHDKIIDPEKRVPTQGMFDKNGIKGGLKSVSLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 SHSFNWRKANKYQLCAQGVEEPNNTQNSHDKIIDPEKRVPTQGMFDKNGIKGGLKSVSLF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 TSKLAKPSTMFVSSTEELNQKSFSGPSNLGKFTKGTLLGRTSYSSINTPKSQLNGFYGNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 TSKLAKPSTMFVSSTEELNQKSFSGPSNLGKFTKGTLLGRTSYSSINTPKSQLNGFYGNR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 SAGSMQRPRANSCATRSSSGESLAQSPDSSKSINCEKMVRSQSFSHSIQNSFLPPSSITR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 SAGSMQRPRANSCATRSSSGESLAQSPDSSKSINCEKMVRSQSFSHSIQNSFLPPSSITR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 SHSFNRAVDLTKPYQNQQLSIRVPLRSSMLTRNSRQPEVLNGNEHLGYGFNRPYAAGGKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 SHSFNRAVDLTKPYQNQQLSIRVPLRSSMLTRNSRQPEVLNGNEHLGYGFNRPYAAGGKK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 LALPNGPGVTSTLGYRMVHPSLLKSSRSPFSGTMTVDGNKNSPADTCVEEDATVLAKDRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 LALPNGPGVTSTLGYRMVHPSLLKSSRSPFSGTMTVDGNKNSPADTCVEEDATVLAKDRA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 ANKDQELIENESYRTKNNQTMKHDAKMRYLSDDVDDISLSSLSSSDKNDLSEDFSDDFID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 ANKDQELIENESYRTKNNQTMKHDAKMRYLSDDVDDISLSSLSSSDKNDLSEDFSDDFID 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 IEDSNRTRITPEEMSLKEEKHENGPPQDMFDSPKENEKAFSKTDEWIDISVSDRSECTKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 IEDSNRTRITPEEMSLKEEKHENGPPQDMFDSPKENEKAFSKTDEWIDISVSDRSECTKH 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 TSGNNLVSPDTDYRAGSSFELSPSDSSDGTYMWDEEGLEPIGNVHPVGSYESSEMNSIDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 TSGNNLVSPDTDYRAGSSFELSPSDSSDGTYMWDEEGLEPIGNVHPVGSYESSEMNSIDI 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 LNNLESCDLEDDDLMLDVDLPEDAPLENVECDNMNRFDRPDRNVRQPQEGFWKRPPQRWS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 LNNLESCDLEDDDLMLDVDLPEDAPLENVECDNMNRFDRPDRNVRQPQEGFWKRPPQRWS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 GQEHYHLSHPDHYHHHGKSDLSRGSPYRESPLGHFESYGGMPFFQAQKMFVDVPENTVIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 GQEHYHLSHPDHYHHHGKSDLSRGSPYRESPLGHFESYGGMPFFQAQKMFVDVPENTVIL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 DEMTLRHMVQDCTAVKTQLLKLKRLLHQHDGSGSLHDIQLSLPSSPEPEDGDKVYKNEDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 DEMTLRHMVQDCTAVKTQLLKLKRLLHQHDGSGSLHDIQLSLPSSPEPEDGDKVYKNEDL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 LNEIKQLKDEIKKKDEKIQLLELQLATQHICHQKCKEEKCTYADKYTQTPWRRIPPQVLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 LNEIKQLKDEIKKKDEKIQLLELQLATQHICHQKCKEEKCTYADKYTQTPWRRIPPQVLQ 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 PSSSLPRPTDHTQGKLIKPQRIEARSECSIQDMHQGGAHPEESFTHVLHQESNYGLEEQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 PSSSLPRPTDHTQGKLIKPQRIEARSECSIQDMHQGGAHPEESFTHVLHQESNYGLEEQP 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 FSSGPQLTMDVAKSTPSEANLNITVNAQEPYHLANNQISDMQFIPTSLQTPPESSTVDQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 FSSGPQLTMDVAKSTPSEANLNITVNAQEPYHLANNQISDMQFIPTSLQTPPESSTVDQA 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 KRVGRNQSPPVGYMSQPKSLQLLKPSILSSLVPPPVSESSPSRTPTCKKSPIITTCNSAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 KRVGRNQSPPVGYMSQPKSLQLLKPSILSSLVPPPVSESSPSRTPTCKKSPIITTCNSAK 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 LQPTSSQTNLANNQNLKASKLRPPSGSFKQKQTNSPQLEPQSFQAKTSIPRPLTQRKEIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 LQPTSSQTNLANNQNLKASKLRPPSGSFKQKQTNSPQLEPQSFQAKTSIPRPLTQRKEIM 970 980 990 1000 1010 1020 1030 1040 pF1KA1 QNPNGNLHSGDCLASNRYSRLPKPKIH ::::::::::::::::::::::::::: CCDS60 QNPNGNLHSGDCLASNRYSRLPKPKIH 1030 1040 >>CCDS31235.1 CCSER2 gene_id:54462|Hs108|chr10 (834 aa) initn: 5272 init1: 5237 opt: 5258 Z-score: 4129.6 bits: 775.4 E(32554): 0 Smith-Waterman score: 5258; 95.6% identity (97.1% similar) in 821 aa overlap (1-820:1-821) 10 20 30 40 50 60 pF1KA1 MEEKTQIKTFLGSKLPKYGTKSVRSTLQPMPNGTPVNLLGTSKNSNVKSYIKNNGSDCPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 MEEKTQIKTFLGSKLPKYGTKSVRSTLQPMPNGTPVNLLGTSKNSNVKSYIKNNGSDCPS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 SHSFNWRKANKYQLCAQGVEEPNNTQNSHDKIIDPEKRVPTQGMFDKNGIKGGLKSVSLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 SHSFNWRKANKYQLCAQGVEEPNNTQNSHDKIIDPEKRVPTQGMFDKNGIKGGLKSVSLF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 TSKLAKPSTMFVSSTEELNQKSFSGPSNLGKFTKGTLLGRTSYSSINTPKSQLNGFYGNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 TSKLAKPSTMFVSSTEELNQKSFSGPSNLGKFTKGTLLGRTSYSSINTPKSQLNGFYGNR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 SAGSMQRPRANSCATRSSSGESLAQSPDSSKSINCEKMVRSQSFSHSIQNSFLPPSSITR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 SAGSMQRPRANSCATRSSSGESLAQSPDSSKSINCEKMVRSQSFSHSIQNSFLPPSSITR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 SHSFNRAVDLTKPYQNQQLSIRVPLRSSMLTRNSRQPEVLNGNEHLGYGFNRPYAAGGKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 SHSFNRAVDLTKPYQNQQLSIRVPLRSSMLTRNSRQPEVLNGNEHLGYGFNRPYAAGGKK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 LALPNGPGVTSTLGYRMVHPSLLKSSRSPFSGTMTVDGNKNSPADTCVEEDATVLAKDRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 LALPNGPGVTSTLGYRMVHPSLLKSSRSPFSGTMTVDGNKNSPADTCVEEDATVLAKDRA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 ANKDQELIENESYRTKNNQTMKHDAKMRYLSDDVDDISLSSLSSSDKNDLSEDFSDDFID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 ANKDQELIENESYRTKNNQTMKHDAKMRYLSDDVDDISLSSLSSSDKNDLSEDFSDDFID 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 IEDSNRTRITPEEMSLKEEKHENGPPQDMFDSPKENEKAFSKTDEWIDISVSDRSECTKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 IEDSNRTRITPEEMSLKEEKHENGPPQDMFDSPKENEKAFSKTDEWIDISVSDRSECTKH 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 TSGNNLVSPDTDYRAGSSFELSPSDSSDGTYMWDEEGLEPIGNVHPVGSYESSEMNSIDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 TSGNNLVSPDTDYRAGSSFELSPSDSSDGTYMWDEEGLEPIGNVHPVGSYESSEMNSIDI 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 LNNLESCDLEDDDLMLDVDLPEDAPLENVECDNMNRFDRPDRNVRQPQEGFWKRPPQRWS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 LNNLESCDLEDDDLMLDVDLPEDAPLENVECDNMNRFDRPDRNVRQPQEGFWKRPPQRWS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 GQEHYHLSHPDHYHHHGKSDLSRGSPYRESPLGHFESYGGMPFFQAQKMFVDVPENTVIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 GQEHYHLSHPDHYHHHGKSDLSRGSPYRESPLGHFESYGGMPFFQAQKMFVDVPENTVIL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 DEMTLRHMVQDCTAVKTQLLKLKRLLHQHDGSGSLHDIQLSLPSSPEPEDGDKVYKNEDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 DEMTLRHMVQDCTAVKTQLLKLKRLLHQHDGSGSLHDIQLSLPSSPEPEDGDKVYKNEDL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 LNEIKQLKDEIKKKDEKIQLLELQLATQHICHQKCKEEKCTYADKYTQTPWRRIPPQVLQ ::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 LNEIKQLKDEIKKKDEKIQLLELQLATQHICHQKCKEEKCTYADKYTQTPWRRIPGGYSA 730 740 750 760 770 780 790 800 810 820 830 pF1KA1 PSSSLPRPTDHTQGKLIKPQRIEARSECSIQDMHQGG-AHPEESFTHVLHQESNYGLEEQ :: : . . . . . :.: .. : ..:. : .:: CCDS31 PSFSPWQGSFQGIPRTVPPHRRQTSSTTAFQQPSQTHRSHPGKTNKATTYRGPQ 790 800 810 820 830 840 850 860 870 880 890 pF1KA1 PFSSGPQLTMDVAKSTPSEANLNITVNAQEPYHLANNQISDMQFIPTSLQTPPESSTVDQ >>CCDS73159.1 CCSER2 gene_id:54462|Hs108|chr10 (567 aa) initn: 3551 init1: 3551 opt: 3551 Z-score: 2794.1 bits: 527.8 E(32554): 2.6e-149 Smith-Waterman score: 3551; 100.0% identity (100.0% similar) in 538 aa overlap (1-538:1-538) 10 20 30 40 50 60 pF1KA1 MEEKTQIKTFLGSKLPKYGTKSVRSTLQPMPNGTPVNLLGTSKNSNVKSYIKNNGSDCPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 MEEKTQIKTFLGSKLPKYGTKSVRSTLQPMPNGTPVNLLGTSKNSNVKSYIKNNGSDCPS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 SHSFNWRKANKYQLCAQGVEEPNNTQNSHDKIIDPEKRVPTQGMFDKNGIKGGLKSVSLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 SHSFNWRKANKYQLCAQGVEEPNNTQNSHDKIIDPEKRVPTQGMFDKNGIKGGLKSVSLF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 TSKLAKPSTMFVSSTEELNQKSFSGPSNLGKFTKGTLLGRTSYSSINTPKSQLNGFYGNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 TSKLAKPSTMFVSSTEELNQKSFSGPSNLGKFTKGTLLGRTSYSSINTPKSQLNGFYGNR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 SAGSMQRPRANSCATRSSSGESLAQSPDSSKSINCEKMVRSQSFSHSIQNSFLPPSSITR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 SAGSMQRPRANSCATRSSSGESLAQSPDSSKSINCEKMVRSQSFSHSIQNSFLPPSSITR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 SHSFNRAVDLTKPYQNQQLSIRVPLRSSMLTRNSRQPEVLNGNEHLGYGFNRPYAAGGKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 SHSFNRAVDLTKPYQNQQLSIRVPLRSSMLTRNSRQPEVLNGNEHLGYGFNRPYAAGGKK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 LALPNGPGVTSTLGYRMVHPSLLKSSRSPFSGTMTVDGNKNSPADTCVEEDATVLAKDRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 LALPNGPGVTSTLGYRMVHPSLLKSSRSPFSGTMTVDGNKNSPADTCVEEDATVLAKDRA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 ANKDQELIENESYRTKNNQTMKHDAKMRYLSDDVDDISLSSLSSSDKNDLSEDFSDDFID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 ANKDQELIENESYRTKNNQTMKHDAKMRYLSDDVDDISLSSLSSSDKNDLSEDFSDDFID 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 IEDSNRTRITPEEMSLKEEKHENGPPQDMFDSPKENEKAFSKTDEWIDISVSDRSECTKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 IEDSNRTRITPEEMSLKEEKHENGPPQDMFDSPKENEKAFSKTDEWIDISVSDRSECTKH 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 TSGNNLVSPDTDYRAGSSFELSPSDSSDGTYMWDEEGLEPIGNVHPVGSYESSEMNSIDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 TSGNNLVSPDTDYRAGSSFELSPSDSSDGTYMWDEEGLEPIGNVHPVGSYESSEMNSIVC 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 LNNLESCDLEDDDLMLDVDLPEDAPLENVECDNMNRFDRPDRNVRQPQEGFWKRPPQRWS CCDS73 MDLYTLGIFCLPYYRETCDMIDFVKNL 550 560 >>CCDS60583.1 CCSER2 gene_id:54462|Hs108|chr10 (261 aa) initn: 1467 init1: 1443 opt: 1464 Z-score: 1163.3 bits: 224.9 E(32554): 1.8e-58 Smith-Waterman score: 1464; 85.5% identity (90.3% similar) in 248 aa overlap (574-820:1-248) 550 560 570 580 590 600 pF1KA1 LESCDLEDDDLMLDVDLPEDAPLENVECDNMNRFDRPDRNVRQPQEGFWKRPPQRWSGQE :::::::::::::::::::::::::::::: CCDS60 MNRFDRPDRNVRQPQEGFWKRPPQRWSGQE 10 20 30 610 620 630 640 650 660 pF1KA1 HYHLSHPDHYHHHGKSDLSRGSPYRESPLGHFESYGGMPFFQAQKMFVDVPENTVILDEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 HYHLSHPDHYHHHGKSDLSRGSPYRESPLGHFESYGGMPFFQAQKMFVDVPENTVILDEM 40 50 60 70 80 90 670 680 690 700 710 720 pF1KA1 TLRHMVQDCTAVKTQLLKLKRLLHQHDGSGSLHDIQLSLPSSPEPEDGDKVYKNEDLLNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 TLRHMVQDCTAVKTQLLKLKRLLHQHDGSGSLHDIQLSLPSSPEPEDGDKVYKNEDLLNE 100 110 120 130 140 150 730 740 750 760 770 780 pF1KA1 IKQLKDEIKKKDEKIQLLELQLATQHICHQKCKEEKCTYADKYTQTPWRRIPPQVLQPSS :::::::::::::::::::::::::::::::::::::::::::::::::::: :: CCDS60 IKQLKDEIKKKDEKIQLLELQLATQHICHQKCKEEKCTYADKYTQTPWRRIPGGYSAPSF 160 170 180 190 200 210 790 800 810 820 830 840 pF1KA1 SLPRPTDHTQGKLIKPQRIEARSECSIQDMHQGG-AHPEESFTHVLHQESNYGLEEQPFS : . . . . . :.: .. : ..:. : .:: CCDS60 SPWQGSFQGIPRTVPPHRRQTSSTTAFQQPSQTHRSHPGKTNKATTYRGPQ 220 230 240 250 260 850 860 870 880 890 900 pF1KA1 SGPQLTMDVAKSTPSEANLNITVNAQEPYHLANNQISDMQFIPTSLQTPPESSTVDQAKR 1047 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 20:33:09 2016 done: Wed Nov 2 20:33:10 2016 Total Scan time: 3.900 Total Display time: 0.070 Function used was FASTA [36.3.4 Apr, 2011]