FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1140, 739 aa 1>>>pF1KA1140 739 - 739 aa - 739 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.0677+/-0.000449; mu= 16.7509+/- 0.028 mean_var=106.2897+/-22.725, 0's: 0 Z-trim(112.4): 53 B-trim: 882 in 2/53 Lambda= 0.124402 statistics sampled from 21283 (21333) to 21283 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.606), E-opt: 0.2 (0.25), width: 16 Scan time: 8.500 The best scores are: opt bits E(85289) XP_005264496 (OMIM: 243150,609332) PREDICTED: tetr ( 739) 4853 882.7 0 XP_011531300 (OMIM: 243150,609332) PREDICTED: tetr ( 739) 4853 882.7 0 XP_016860017 (OMIM: 243150,609332) PREDICTED: tetr ( 739) 4435 807.7 0 XP_016860016 (OMIM: 243150,609332) PREDICTED: tetr ( 770) 4435 807.7 0 XP_016860014 (OMIM: 243150,609332) PREDICTED: tetr ( 802) 4435 807.7 0 NP_001275882 (OMIM: 243150,609332) tetratricopepti ( 824) 4435 807.7 0 NP_065191 (OMIM: 243150,609332) tetratricopeptide ( 858) 4435 807.7 0 XP_011531302 (OMIM: 243150,609332) PREDICTED: tetr ( 598) 3869 706.0 1.1e-202 XP_016860018 (OMIM: 243150,609332) PREDICTED: tetr ( 730) 3517 642.9 1.4e-183 NP_001275884 (OMIM: 243150,609332) tetratricopepti ( 504) 3253 595.4 1.9e-169 XP_011531303 (OMIM: 243150,609332) PREDICTED: tetr ( 509) 3249 594.7 3.1e-169 XP_011531301 (OMIM: 243150,609332) PREDICTED: tetr ( 681) 3244 593.9 7.2e-169 NP_001275880 (OMIM: 243150,609332) tetratricopepti ( 882) 3019 553.6 1.3e-156 XP_016860019 (OMIM: 243150,609332) PREDICTED: tetr ( 632) 2761 507.2 8.5e-143 XP_016860013 (OMIM: 243150,609332) PREDICTED: tetr ( 819) 2760 507.1 1.2e-142 XP_016860015 (OMIM: 243150,609332) PREDICTED: tetr ( 775) 2058 381.1 9.5e-105 >>XP_005264496 (OMIM: 243150,609332) PREDICTED: tetratri (739 aa) initn: 4853 init1: 4853 opt: 4853 Z-score: 4712.9 bits: 882.7 E(85289): 0 Smith-Waterman score: 4853; 99.9% identity (100.0% similar) in 739 aa overlap (1-739:1-739) 10 20 30 40 50 60 pF1KA1 MPSACTHGPGLMTCPWRTSPCIRCGCCRRLLSSKHASGFLGEHSPGGQRSCRGGLSLERL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MPSACTHGPGLMTCPWRTSPCIRCGCCRRLLSSKHASGFLGEHSPGGQRSCRGGLSLERL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 PNSIASRFRLTEREEEVITCFERASWIAQVFLQELEKTTNNSTSRHLKGCHPLDYELTYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PNSIASRFRLTEREEEVITCFERASWIAQVFLQELEKTTNNSTSRHLKGCHPLDYELTYF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 LEAALQSAYVKNLKKGNIVKGMRELREVLRTVETKATQNFKVMAAKHLAGVLLHSLSEEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LEAALQSAYVKNLKKGNIVKGMRELREVLRTVETKATQNFKVMAAKHLAGVLLHSLSEEC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 YWSPLSHPLPEFMGKEESSFATQALRKPHLYEGDNLYCPKDNIEEALLLLLISESMATRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YWSPLSHPLPEFMGKEESSFATQALRKPHLYEGDNLYCPKDNIEEALLLLLISESMATRD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 VVLSRVPEQEEDRTVSLQNAAAIYDLLSITLGRRGQYVMLSECLERAMKFAFGEFHLWYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VVLSRVPEQEEDRTVSLQNAAAIYDLLSITLGRRGQYVMLSECLERAMKFAFGEFHLWYQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 VALSMVACGKSAYAVSLLRECVKLRPSDPTVPLMAAKVCIGSLRWLEEAEHFAMMVISLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VALSMVACGKSAYAVSLLRECVKLRPSDPTVPLMAAKVCIGSLRWLEEAEHFAMMVISLG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 EEAGEFLPKGYLALGLTYSLQATDATLKSKQDELHRKALQTLERAQQLAPSDPQVILYVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EEAGEFLPKGYLALGLTYSLQATDATLKSKQDELHRKALQTLERAQQLAPSDPQVILYVS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 LQLALVRQISSAMEQLQEALKVRKDDAHALHLLALLFSAQKHHQHALDVVNMAITEHPEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LQLALVRQISSAMEQLQEALKVRKDDAHALHLLALLFSAQKHHQHALDVVNMAITEHPEN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 FNLIFTKVKLEQVLKGPEEALVTCRQVLRLWQTLYSFSQLGGLEKDGSFGEGLTMKKQSG :::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FNLMFTKVKLEQVLKGPEEALVTCRQVLRLWQTLYSFSQLGGLEKDGSFGEGLTMKKQSG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 MHLTLPDAHDADSGSRRASSIAASRLEEAMSELTMPSSVLKQGPMQLWTTLEQIWLQAAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MHLTLPDAHDADSGSRRASSIAASRLEEAMSELTMPSSVLKQGPMQLWTTLEQIWLQAAE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 LFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGV 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 RIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTA 670 680 690 700 710 720 730 pF1KA1 LELEASSPVLPFSIIPREL ::::::::::::::::::: XP_005 LELEASSPVLPFSIIPREL 730 >>XP_011531300 (OMIM: 243150,609332) PREDICTED: tetratri (739 aa) initn: 4853 init1: 4853 opt: 4853 Z-score: 4712.9 bits: 882.7 E(85289): 0 Smith-Waterman score: 4853; 99.9% identity (100.0% similar) in 739 aa overlap (1-739:1-739) 10 20 30 40 50 60 pF1KA1 MPSACTHGPGLMTCPWRTSPCIRCGCCRRLLSSKHASGFLGEHSPGGQRSCRGGLSLERL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MPSACTHGPGLMTCPWRTSPCIRCGCCRRLLSSKHASGFLGEHSPGGQRSCRGGLSLERL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 PNSIASRFRLTEREEEVITCFERASWIAQVFLQELEKTTNNSTSRHLKGCHPLDYELTYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PNSIASRFRLTEREEEVITCFERASWIAQVFLQELEKTTNNSTSRHLKGCHPLDYELTYF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 LEAALQSAYVKNLKKGNIVKGMRELREVLRTVETKATQNFKVMAAKHLAGVLLHSLSEEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LEAALQSAYVKNLKKGNIVKGMRELREVLRTVETKATQNFKVMAAKHLAGVLLHSLSEEC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 YWSPLSHPLPEFMGKEESSFATQALRKPHLYEGDNLYCPKDNIEEALLLLLISESMATRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YWSPLSHPLPEFMGKEESSFATQALRKPHLYEGDNLYCPKDNIEEALLLLLISESMATRD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 VVLSRVPEQEEDRTVSLQNAAAIYDLLSITLGRRGQYVMLSECLERAMKFAFGEFHLWYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVLSRVPEQEEDRTVSLQNAAAIYDLLSITLGRRGQYVMLSECLERAMKFAFGEFHLWYQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 VALSMVACGKSAYAVSLLRECVKLRPSDPTVPLMAAKVCIGSLRWLEEAEHFAMMVISLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VALSMVACGKSAYAVSLLRECVKLRPSDPTVPLMAAKVCIGSLRWLEEAEHFAMMVISLG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 EEAGEFLPKGYLALGLTYSLQATDATLKSKQDELHRKALQTLERAQQLAPSDPQVILYVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEAGEFLPKGYLALGLTYSLQATDATLKSKQDELHRKALQTLERAQQLAPSDPQVILYVS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 LQLALVRQISSAMEQLQEALKVRKDDAHALHLLALLFSAQKHHQHALDVVNMAITEHPEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQLALVRQISSAMEQLQEALKVRKDDAHALHLLALLFSAQKHHQHALDVVNMAITEHPEN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 FNLIFTKVKLEQVLKGPEEALVTCRQVLRLWQTLYSFSQLGGLEKDGSFGEGLTMKKQSG :::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FNLMFTKVKLEQVLKGPEEALVTCRQVLRLWQTLYSFSQLGGLEKDGSFGEGLTMKKQSG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 MHLTLPDAHDADSGSRRASSIAASRLEEAMSELTMPSSVLKQGPMQLWTTLEQIWLQAAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MHLTLPDAHDADSGSRRASSIAASRLEEAMSELTMPSSVLKQGPMQLWTTLEQIWLQAAE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 LFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGV 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 RIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTA 670 680 690 700 710 720 730 pF1KA1 LELEASSPVLPFSIIPREL ::::::::::::::::::: XP_011 LELEASSPVLPFSIIPREL 730 >>XP_016860017 (OMIM: 243150,609332) PREDICTED: tetratri (739 aa) initn: 4435 init1: 4435 opt: 4435 Z-score: 4307.5 bits: 807.7 E(85289): 0 Smith-Waterman score: 4435; 99.9% identity (100.0% similar) in 686 aa overlap (54-739:54-739) 30 40 50 60 70 80 pF1KA1 CGCCRRLLSSKHASGFLGEHSPGGQRSCRGGLSLERLPNSIASRFRLTEREEEVITCFER :::::::::::::::::::::::::::::: XP_016 MYARAGIDDMSMENKPLYQMRLLSEAFVIKGLSLERLPNSIASRFRLTEREEEVITCFER 30 40 50 60 70 80 90 100 110 120 130 140 pF1KA1 ASWIAQVFLQELEKTTNNSTSRHLKGCHPLDYELTYFLEAALQSAYVKNLKKGNIVKGMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASWIAQVFLQELEKTTNNSTSRHLKGCHPLDYELTYFLEAALQSAYVKNLKKGNIVKGMR 90 100 110 120 130 140 150 160 170 180 190 200 pF1KA1 ELREVLRTVETKATQNFKVMAAKHLAGVLLHSLSEECYWSPLSHPLPEFMGKEESSFATQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELREVLRTVETKATQNFKVMAAKHLAGVLLHSLSEECYWSPLSHPLPEFMGKEESSFATQ 150 160 170 180 190 200 210 220 230 240 250 260 pF1KA1 ALRKPHLYEGDNLYCPKDNIEEALLLLLISESMATRDVVLSRVPEQEEDRTVSLQNAAAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALRKPHLYEGDNLYCPKDNIEEALLLLLISESMATRDVVLSRVPEQEEDRTVSLQNAAAI 210 220 230 240 250 260 270 280 290 300 310 320 pF1KA1 YDLLSITLGRRGQYVMLSECLERAMKFAFGEFHLWYQVALSMVACGKSAYAVSLLRECVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YDLLSITLGRRGQYVMLSECLERAMKFAFGEFHLWYQVALSMVACGKSAYAVSLLRECVK 270 280 290 300 310 320 330 340 350 360 370 380 pF1KA1 LRPSDPTVPLMAAKVCIGSLRWLEEAEHFAMMVISLGEEAGEFLPKGYLALGLTYSLQAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRPSDPTVPLMAAKVCIGSLRWLEEAEHFAMMVISLGEEAGEFLPKGYLALGLTYSLQAT 330 340 350 360 370 380 390 400 410 420 430 440 pF1KA1 DATLKSKQDELHRKALQTLERAQQLAPSDPQVILYVSLQLALVRQISSAMEQLQEALKVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DATLKSKQDELHRKALQTLERAQQLAPSDPQVILYVSLQLALVRQISSAMEQLQEALKVR 390 400 410 420 430 440 450 460 470 480 490 500 pF1KA1 KDDAHALHLLALLFSAQKHHQHALDVVNMAITEHPENFNLIFTKVKLEQVLKGPEEALVT ::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::: XP_016 KDDAHALHLLALLFSAQKHHQHALDVVNMAITEHPENFNLMFTKVKLEQVLKGPEEALVT 450 460 470 480 490 500 510 520 530 540 550 560 pF1KA1 CRQVLRLWQTLYSFSQLGGLEKDGSFGEGLTMKKQSGMHLTLPDAHDADSGSRRASSIAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CRQVLRLWQTLYSFSQLGGLEKDGSFGEGLTMKKQSGMHLTLPDAHDADSGSRRASSIAA 510 520 530 540 550 560 570 580 590 600 610 620 pF1KA1 SRLEEAMSELTMPSSVLKQGPMQLWTTLEQIWLQAAELFMEQQHLKEAGFCIQEAAGLFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SRLEEAMSELTMPSSVLKQGPMQLWTTLEQIWLQAAELFMEQQHLKEAGFCIQEAAGLFP 570 580 590 600 610 620 630 640 650 660 670 680 pF1KA1 TSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVL 630 640 650 660 670 680 690 700 710 720 730 pF1KA1 RDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELEASSPVLPFSIIPREL :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELEASSPVLPFSIIPREL 690 700 710 720 730 >>XP_016860016 (OMIM: 243150,609332) PREDICTED: tetratri (770 aa) initn: 4435 init1: 4435 opt: 4435 Z-score: 4307.2 bits: 807.7 E(85289): 0 Smith-Waterman score: 4435; 99.9% identity (100.0% similar) in 686 aa overlap (54-739:85-770) 30 40 50 60 70 80 pF1KA1 CGCCRRLLSSKHASGFLGEHSPGGQRSCRGGLSLERLPNSIASRFRLTEREEEVITCFER :::::::::::::::::::::::::::::: XP_016 MYARAGIDDMSMENKPLYQMRLLSEAFVIKGLSLERLPNSIASRFRLTEREEEVITCFER 60 70 80 90 100 110 90 100 110 120 130 140 pF1KA1 ASWIAQVFLQELEKTTNNSTSRHLKGCHPLDYELTYFLEAALQSAYVKNLKKGNIVKGMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASWIAQVFLQELEKTTNNSTSRHLKGCHPLDYELTYFLEAALQSAYVKNLKKGNIVKGMR 120 130 140 150 160 170 150 160 170 180 190 200 pF1KA1 ELREVLRTVETKATQNFKVMAAKHLAGVLLHSLSEECYWSPLSHPLPEFMGKEESSFATQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELREVLRTVETKATQNFKVMAAKHLAGVLLHSLSEECYWSPLSHPLPEFMGKEESSFATQ 180 190 200 210 220 230 210 220 230 240 250 260 pF1KA1 ALRKPHLYEGDNLYCPKDNIEEALLLLLISESMATRDVVLSRVPEQEEDRTVSLQNAAAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALRKPHLYEGDNLYCPKDNIEEALLLLLISESMATRDVVLSRVPEQEEDRTVSLQNAAAI 240 250 260 270 280 290 270 280 290 300 310 320 pF1KA1 YDLLSITLGRRGQYVMLSECLERAMKFAFGEFHLWYQVALSMVACGKSAYAVSLLRECVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YDLLSITLGRRGQYVMLSECLERAMKFAFGEFHLWYQVALSMVACGKSAYAVSLLRECVK 300 310 320 330 340 350 330 340 350 360 370 380 pF1KA1 LRPSDPTVPLMAAKVCIGSLRWLEEAEHFAMMVISLGEEAGEFLPKGYLALGLTYSLQAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRPSDPTVPLMAAKVCIGSLRWLEEAEHFAMMVISLGEEAGEFLPKGYLALGLTYSLQAT 360 370 380 390 400 410 390 400 410 420 430 440 pF1KA1 DATLKSKQDELHRKALQTLERAQQLAPSDPQVILYVSLQLALVRQISSAMEQLQEALKVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DATLKSKQDELHRKALQTLERAQQLAPSDPQVILYVSLQLALVRQISSAMEQLQEALKVR 420 430 440 450 460 470 450 460 470 480 490 500 pF1KA1 KDDAHALHLLALLFSAQKHHQHALDVVNMAITEHPENFNLIFTKVKLEQVLKGPEEALVT ::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::: XP_016 KDDAHALHLLALLFSAQKHHQHALDVVNMAITEHPENFNLMFTKVKLEQVLKGPEEALVT 480 490 500 510 520 530 510 520 530 540 550 560 pF1KA1 CRQVLRLWQTLYSFSQLGGLEKDGSFGEGLTMKKQSGMHLTLPDAHDADSGSRRASSIAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CRQVLRLWQTLYSFSQLGGLEKDGSFGEGLTMKKQSGMHLTLPDAHDADSGSRRASSIAA 540 550 560 570 580 590 570 580 590 600 610 620 pF1KA1 SRLEEAMSELTMPSSVLKQGPMQLWTTLEQIWLQAAELFMEQQHLKEAGFCIQEAAGLFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SRLEEAMSELTMPSSVLKQGPMQLWTTLEQIWLQAAELFMEQQHLKEAGFCIQEAAGLFP 600 610 620 630 640 650 630 640 650 660 670 680 pF1KA1 TSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVL 660 670 680 690 700 710 690 700 710 720 730 pF1KA1 RDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELEASSPVLPFSIIPREL :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELEASSPVLPFSIIPREL 720 730 740 750 760 770 >>XP_016860014 (OMIM: 243150,609332) PREDICTED: tetratri (802 aa) initn: 4435 init1: 4435 opt: 4435 Z-score: 4307.0 bits: 807.7 E(85289): 0 Smith-Waterman score: 4435; 99.9% identity (100.0% similar) in 686 aa overlap (54-739:117-802) 30 40 50 60 70 80 pF1KA1 CGCCRRLLSSKHASGFLGEHSPGGQRSCRGGLSLERLPNSIASRFRLTEREEEVITCFER :::::::::::::::::::::::::::::: XP_016 MYARAGIDDMSMENKPLYQMRLLSEAFVIKGLSLERLPNSIASRFRLTEREEEVITCFER 90 100 110 120 130 140 90 100 110 120 130 140 pF1KA1 ASWIAQVFLQELEKTTNNSTSRHLKGCHPLDYELTYFLEAALQSAYVKNLKKGNIVKGMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASWIAQVFLQELEKTTNNSTSRHLKGCHPLDYELTYFLEAALQSAYVKNLKKGNIVKGMR 150 160 170 180 190 200 150 160 170 180 190 200 pF1KA1 ELREVLRTVETKATQNFKVMAAKHLAGVLLHSLSEECYWSPLSHPLPEFMGKEESSFATQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELREVLRTVETKATQNFKVMAAKHLAGVLLHSLSEECYWSPLSHPLPEFMGKEESSFATQ 210 220 230 240 250 260 210 220 230 240 250 260 pF1KA1 ALRKPHLYEGDNLYCPKDNIEEALLLLLISESMATRDVVLSRVPEQEEDRTVSLQNAAAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALRKPHLYEGDNLYCPKDNIEEALLLLLISESMATRDVVLSRVPEQEEDRTVSLQNAAAI 270 280 290 300 310 320 270 280 290 300 310 320 pF1KA1 YDLLSITLGRRGQYVMLSECLERAMKFAFGEFHLWYQVALSMVACGKSAYAVSLLRECVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YDLLSITLGRRGQYVMLSECLERAMKFAFGEFHLWYQVALSMVACGKSAYAVSLLRECVK 330 340 350 360 370 380 330 340 350 360 370 380 pF1KA1 LRPSDPTVPLMAAKVCIGSLRWLEEAEHFAMMVISLGEEAGEFLPKGYLALGLTYSLQAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRPSDPTVPLMAAKVCIGSLRWLEEAEHFAMMVISLGEEAGEFLPKGYLALGLTYSLQAT 390 400 410 420 430 440 390 400 410 420 430 440 pF1KA1 DATLKSKQDELHRKALQTLERAQQLAPSDPQVILYVSLQLALVRQISSAMEQLQEALKVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DATLKSKQDELHRKALQTLERAQQLAPSDPQVILYVSLQLALVRQISSAMEQLQEALKVR 450 460 470 480 490 500 450 460 470 480 490 500 pF1KA1 KDDAHALHLLALLFSAQKHHQHALDVVNMAITEHPENFNLIFTKVKLEQVLKGPEEALVT ::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::: XP_016 KDDAHALHLLALLFSAQKHHQHALDVVNMAITEHPENFNLMFTKVKLEQVLKGPEEALVT 510 520 530 540 550 560 510 520 530 540 550 560 pF1KA1 CRQVLRLWQTLYSFSQLGGLEKDGSFGEGLTMKKQSGMHLTLPDAHDADSGSRRASSIAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CRQVLRLWQTLYSFSQLGGLEKDGSFGEGLTMKKQSGMHLTLPDAHDADSGSRRASSIAA 570 580 590 600 610 620 570 580 590 600 610 620 pF1KA1 SRLEEAMSELTMPSSVLKQGPMQLWTTLEQIWLQAAELFMEQQHLKEAGFCIQEAAGLFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SRLEEAMSELTMPSSVLKQGPMQLWTTLEQIWLQAAELFMEQQHLKEAGFCIQEAAGLFP 630 640 650 660 670 680 630 640 650 660 670 680 pF1KA1 TSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVL 690 700 710 720 730 740 690 700 710 720 730 pF1KA1 RDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELEASSPVLPFSIIPREL :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELEASSPVLPFSIIPREL 750 760 770 780 790 800 >>NP_001275882 (OMIM: 243150,609332) tetratricopeptide r (824 aa) initn: 4435 init1: 4435 opt: 4435 Z-score: 4306.8 bits: 807.7 E(85289): 0 Smith-Waterman score: 4435; 99.9% identity (100.0% similar) in 686 aa overlap (54-739:139-824) 30 40 50 60 70 80 pF1KA1 CGCCRRLLSSKHASGFLGEHSPGGQRSCRGGLSLERLPNSIASRFRLTEREEEVITCFER :::::::::::::::::::::::::::::: NP_001 MYARAGIDDMSMENKPLYQMRLLSEAFVIKGLSLERLPNSIASRFRLTEREEEVITCFER 110 120 130 140 150 160 90 100 110 120 130 140 pF1KA1 ASWIAQVFLQELEKTTNNSTSRHLKGCHPLDYELTYFLEAALQSAYVKNLKKGNIVKGMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASWIAQVFLQELEKTTNNSTSRHLKGCHPLDYELTYFLEAALQSAYVKNLKKGNIVKGMR 170 180 190 200 210 220 150 160 170 180 190 200 pF1KA1 ELREVLRTVETKATQNFKVMAAKHLAGVLLHSLSEECYWSPLSHPLPEFMGKEESSFATQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELREVLRTVETKATQNFKVMAAKHLAGVLLHSLSEECYWSPLSHPLPEFMGKEESSFATQ 230 240 250 260 270 280 210 220 230 240 250 260 pF1KA1 ALRKPHLYEGDNLYCPKDNIEEALLLLLISESMATRDVVLSRVPEQEEDRTVSLQNAAAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALRKPHLYEGDNLYCPKDNIEEALLLLLISESMATRDVVLSRVPEQEEDRTVSLQNAAAI 290 300 310 320 330 340 270 280 290 300 310 320 pF1KA1 YDLLSITLGRRGQYVMLSECLERAMKFAFGEFHLWYQVALSMVACGKSAYAVSLLRECVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YDLLSITLGRRGQYVMLSECLERAMKFAFGEFHLWYQVALSMVACGKSAYAVSLLRECVK 350 360 370 380 390 400 330 340 350 360 370 380 pF1KA1 LRPSDPTVPLMAAKVCIGSLRWLEEAEHFAMMVISLGEEAGEFLPKGYLALGLTYSLQAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRPSDPTVPLMAAKVCIGSLRWLEEAEHFAMMVISLGEEAGEFLPKGYLALGLTYSLQAT 410 420 430 440 450 460 390 400 410 420 430 440 pF1KA1 DATLKSKQDELHRKALQTLERAQQLAPSDPQVILYVSLQLALVRQISSAMEQLQEALKVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DATLKSKQDELHRKALQTLERAQQLAPSDPQVILYVSLQLALVRQISSAMEQLQEALKVR 470 480 490 500 510 520 450 460 470 480 490 500 pF1KA1 KDDAHALHLLALLFSAQKHHQHALDVVNMAITEHPENFNLIFTKVKLEQVLKGPEEALVT ::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::: NP_001 KDDAHALHLLALLFSAQKHHQHALDVVNMAITEHPENFNLMFTKVKLEQVLKGPEEALVT 530 540 550 560 570 580 510 520 530 540 550 560 pF1KA1 CRQVLRLWQTLYSFSQLGGLEKDGSFGEGLTMKKQSGMHLTLPDAHDADSGSRRASSIAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CRQVLRLWQTLYSFSQLGGLEKDGSFGEGLTMKKQSGMHLTLPDAHDADSGSRRASSIAA 590 600 610 620 630 640 570 580 590 600 610 620 pF1KA1 SRLEEAMSELTMPSSVLKQGPMQLWTTLEQIWLQAAELFMEQQHLKEAGFCIQEAAGLFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SRLEEAMSELTMPSSVLKQGPMQLWTTLEQIWLQAAELFMEQQHLKEAGFCIQEAAGLFP 650 660 670 680 690 700 630 640 650 660 670 680 pF1KA1 TSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVL 710 720 730 740 750 760 690 700 710 720 730 pF1KA1 RDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELEASSPVLPFSIIPREL :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELEASSPVLPFSIIPREL 770 780 790 800 810 820 >>NP_065191 (OMIM: 243150,609332) tetratricopeptide repe (858 aa) initn: 4435 init1: 4435 opt: 4435 Z-score: 4306.6 bits: 807.7 E(85289): 0 Smith-Waterman score: 4435; 99.9% identity (100.0% similar) in 686 aa overlap (54-739:173-858) 30 40 50 60 70 80 pF1KA1 CGCCRRLLSSKHASGFLGEHSPGGQRSCRGGLSLERLPNSIASRFRLTEREEEVITCFER :::::::::::::::::::::::::::::: NP_065 MYARAGIDDMSMENKPLYQMRLLSEAFVIKGLSLERLPNSIASRFRLTEREEEVITCFER 150 160 170 180 190 200 90 100 110 120 130 140 pF1KA1 ASWIAQVFLQELEKTTNNSTSRHLKGCHPLDYELTYFLEAALQSAYVKNLKKGNIVKGMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 ASWIAQVFLQELEKTTNNSTSRHLKGCHPLDYELTYFLEAALQSAYVKNLKKGNIVKGMR 210 220 230 240 250 260 150 160 170 180 190 200 pF1KA1 ELREVLRTVETKATQNFKVMAAKHLAGVLLHSLSEECYWSPLSHPLPEFMGKEESSFATQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 ELREVLRTVETKATQNFKVMAAKHLAGVLLHSLSEECYWSPLSHPLPEFMGKEESSFATQ 270 280 290 300 310 320 210 220 230 240 250 260 pF1KA1 ALRKPHLYEGDNLYCPKDNIEEALLLLLISESMATRDVVLSRVPEQEEDRTVSLQNAAAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 ALRKPHLYEGDNLYCPKDNIEEALLLLLISESMATRDVVLSRVPEQEEDRTVSLQNAAAI 330 340 350 360 370 380 270 280 290 300 310 320 pF1KA1 YDLLSITLGRRGQYVMLSECLERAMKFAFGEFHLWYQVALSMVACGKSAYAVSLLRECVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 YDLLSITLGRRGQYVMLSECLERAMKFAFGEFHLWYQVALSMVACGKSAYAVSLLRECVK 390 400 410 420 430 440 330 340 350 360 370 380 pF1KA1 LRPSDPTVPLMAAKVCIGSLRWLEEAEHFAMMVISLGEEAGEFLPKGYLALGLTYSLQAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 LRPSDPTVPLMAAKVCIGSLRWLEEAEHFAMMVISLGEEAGEFLPKGYLALGLTYSLQAT 450 460 470 480 490 500 390 400 410 420 430 440 pF1KA1 DATLKSKQDELHRKALQTLERAQQLAPSDPQVILYVSLQLALVRQISSAMEQLQEALKVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 DATLKSKQDELHRKALQTLERAQQLAPSDPQVILYVSLQLALVRQISSAMEQLQEALKVR 510 520 530 540 550 560 450 460 470 480 490 500 pF1KA1 KDDAHALHLLALLFSAQKHHQHALDVVNMAITEHPENFNLIFTKVKLEQVLKGPEEALVT ::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::: NP_065 KDDAHALHLLALLFSAQKHHQHALDVVNMAITEHPENFNLMFTKVKLEQVLKGPEEALVT 570 580 590 600 610 620 510 520 530 540 550 560 pF1KA1 CRQVLRLWQTLYSFSQLGGLEKDGSFGEGLTMKKQSGMHLTLPDAHDADSGSRRASSIAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 CRQVLRLWQTLYSFSQLGGLEKDGSFGEGLTMKKQSGMHLTLPDAHDADSGSRRASSIAA 630 640 650 660 670 680 570 580 590 600 610 620 pF1KA1 SRLEEAMSELTMPSSVLKQGPMQLWTTLEQIWLQAAELFMEQQHLKEAGFCIQEAAGLFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 SRLEEAMSELTMPSSVLKQGPMQLWTTLEQIWLQAAELFMEQQHLKEAGFCIQEAAGLFP 690 700 710 720 730 740 630 640 650 660 670 680 pF1KA1 TSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 TSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVL 750 760 770 780 790 800 690 700 710 720 730 pF1KA1 RDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELEASSPVLPFSIIPREL :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 RDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELEASSPVLPFSIIPREL 810 820 830 840 850 >>XP_011531302 (OMIM: 243150,609332) PREDICTED: tetratri (598 aa) initn: 3869 init1: 3869 opt: 3869 Z-score: 3759.7 bits: 706.0 E(85289): 1.1e-202 Smith-Waterman score: 3869; 99.8% identity (100.0% similar) in 598 aa overlap (142-739:1-598) 120 130 140 150 160 170 pF1KA1 PLDYELTYFLEAALQSAYVKNLKKGNIVKGMRELREVLRTVETKATQNFKVMAAKHLAGV :::::::::::::::::::::::::::::: XP_011 MRELREVLRTVETKATQNFKVMAAKHLAGV 10 20 30 180 190 200 210 220 230 pF1KA1 LLHSLSEECYWSPLSHPLPEFMGKEESSFATQALRKPHLYEGDNLYCPKDNIEEALLLLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLHSLSEECYWSPLSHPLPEFMGKEESSFATQALRKPHLYEGDNLYCPKDNIEEALLLLL 40 50 60 70 80 90 240 250 260 270 280 290 pF1KA1 ISESMATRDVVLSRVPEQEEDRTVSLQNAAAIYDLLSITLGRRGQYVMLSECLERAMKFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ISESMATRDVVLSRVPEQEEDRTVSLQNAAAIYDLLSITLGRRGQYVMLSECLERAMKFA 100 110 120 130 140 150 300 310 320 330 340 350 pF1KA1 FGEFHLWYQVALSMVACGKSAYAVSLLRECVKLRPSDPTVPLMAAKVCIGSLRWLEEAEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FGEFHLWYQVALSMVACGKSAYAVSLLRECVKLRPSDPTVPLMAAKVCIGSLRWLEEAEH 160 170 180 190 200 210 360 370 380 390 400 410 pF1KA1 FAMMVISLGEEAGEFLPKGYLALGLTYSLQATDATLKSKQDELHRKALQTLERAQQLAPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FAMMVISLGEEAGEFLPKGYLALGLTYSLQATDATLKSKQDELHRKALQTLERAQQLAPS 220 230 240 250 260 270 420 430 440 450 460 470 pF1KA1 DPQVILYVSLQLALVRQISSAMEQLQEALKVRKDDAHALHLLALLFSAQKHHQHALDVVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DPQVILYVSLQLALVRQISSAMEQLQEALKVRKDDAHALHLLALLFSAQKHHQHALDVVN 280 290 300 310 320 330 480 490 500 510 520 530 pF1KA1 MAITEHPENFNLIFTKVKLEQVLKGPEEALVTCRQVLRLWQTLYSFSQLGGLEKDGSFGE ::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAITEHPENFNLMFTKVKLEQVLKGPEEALVTCRQVLRLWQTLYSFSQLGGLEKDGSFGE 340 350 360 370 380 390 540 550 560 570 580 590 pF1KA1 GLTMKKQSGMHLTLPDAHDADSGSRRASSIAASRLEEAMSELTMPSSVLKQGPMQLWTTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLTMKKQSGMHLTLPDAHDADSGSRRASSIAASRLEEAMSELTMPSSVLKQGPMQLWTTL 400 410 420 430 440 450 600 610 620 630 640 650 pF1KA1 EQIWLQAAELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EQIWLQAAELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKE 460 470 480 490 500 510 660 670 680 690 700 710 pF1KA1 ALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNE 520 530 540 550 560 570 720 730 pF1KA1 AAVDCFLTALELEASSPVLPFSIIPREL :::::::::::::::::::::::::::: XP_011 AAVDCFLTALELEASSPVLPFSIIPREL 580 590 >>XP_016860018 (OMIM: 243150,609332) PREDICTED: tetratri (730 aa) initn: 3517 init1: 3517 opt: 3517 Z-score: 3417.1 bits: 642.9 E(85289): 1.4e-183 Smith-Waterman score: 3517; 99.8% identity (100.0% similar) in 545 aa overlap (54-598:173-717) 30 40 50 60 70 80 pF1KA1 CGCCRRLLSSKHASGFLGEHSPGGQRSCRGGLSLERLPNSIASRFRLTEREEEVITCFER :::::::::::::::::::::::::::::: XP_016 MYARAGIDDMSMENKPLYQMRLLSEAFVIKGLSLERLPNSIASRFRLTEREEEVITCFER 150 160 170 180 190 200 90 100 110 120 130 140 pF1KA1 ASWIAQVFLQELEKTTNNSTSRHLKGCHPLDYELTYFLEAALQSAYVKNLKKGNIVKGMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASWIAQVFLQELEKTTNNSTSRHLKGCHPLDYELTYFLEAALQSAYVKNLKKGNIVKGMR 210 220 230 240 250 260 150 160 170 180 190 200 pF1KA1 ELREVLRTVETKATQNFKVMAAKHLAGVLLHSLSEECYWSPLSHPLPEFMGKEESSFATQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELREVLRTVETKATQNFKVMAAKHLAGVLLHSLSEECYWSPLSHPLPEFMGKEESSFATQ 270 280 290 300 310 320 210 220 230 240 250 260 pF1KA1 ALRKPHLYEGDNLYCPKDNIEEALLLLLISESMATRDVVLSRVPEQEEDRTVSLQNAAAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALRKPHLYEGDNLYCPKDNIEEALLLLLISESMATRDVVLSRVPEQEEDRTVSLQNAAAI 330 340 350 360 370 380 270 280 290 300 310 320 pF1KA1 YDLLSITLGRRGQYVMLSECLERAMKFAFGEFHLWYQVALSMVACGKSAYAVSLLRECVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YDLLSITLGRRGQYVMLSECLERAMKFAFGEFHLWYQVALSMVACGKSAYAVSLLRECVK 390 400 410 420 430 440 330 340 350 360 370 380 pF1KA1 LRPSDPTVPLMAAKVCIGSLRWLEEAEHFAMMVISLGEEAGEFLPKGYLALGLTYSLQAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRPSDPTVPLMAAKVCIGSLRWLEEAEHFAMMVISLGEEAGEFLPKGYLALGLTYSLQAT 450 460 470 480 490 500 390 400 410 420 430 440 pF1KA1 DATLKSKQDELHRKALQTLERAQQLAPSDPQVILYVSLQLALVRQISSAMEQLQEALKVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DATLKSKQDELHRKALQTLERAQQLAPSDPQVILYVSLQLALVRQISSAMEQLQEALKVR 510 520 530 540 550 560 450 460 470 480 490 500 pF1KA1 KDDAHALHLLALLFSAQKHHQHALDVVNMAITEHPENFNLIFTKVKLEQVLKGPEEALVT ::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::: XP_016 KDDAHALHLLALLFSAQKHHQHALDVVNMAITEHPENFNLMFTKVKLEQVLKGPEEALVT 570 580 590 600 610 620 510 520 530 540 550 560 pF1KA1 CRQVLRLWQTLYSFSQLGGLEKDGSFGEGLTMKKQSGMHLTLPDAHDADSGSRRASSIAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CRQVLRLWQTLYSFSQLGGLEKDGSFGEGLTMKKQSGMHLTLPDAHDADSGSRRASSIAA 630 640 650 660 670 680 570 580 590 600 610 620 pF1KA1 SRLEEAMSELTMPSSVLKQGPMQLWTTLEQIWLQAAELFMEQQHLKEAGFCIQEAAGLFP ::::::::::::::::::::::::::::::::::: XP_016 SRLEEAMSELTMPSSVLKQGPMQLWTTLEQIWLQADIHSTEENSENSI 690 700 710 720 730 630 640 650 660 670 680 pF1KA1 TSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVL >>NP_001275884 (OMIM: 243150,609332) tetratricopeptide r (504 aa) initn: 3253 init1: 3253 opt: 3253 Z-score: 3163.2 bits: 595.4 E(85289): 1.9e-169 Smith-Waterman score: 3253; 99.8% identity (100.0% similar) in 504 aa overlap (236-739:1-504) 210 220 230 240 250 260 pF1KA1 RKPHLYEGDNLYCPKDNIEEALLLLLISESMATRDVVLSRVPEQEEDRTVSLQNAAAIYD :::::::::::::::::::::::::::::: NP_001 MATRDVVLSRVPEQEEDRTVSLQNAAAIYD 10 20 30 270 280 290 300 310 320 pF1KA1 LLSITLGRRGQYVMLSECLERAMKFAFGEFHLWYQVALSMVACGKSAYAVSLLRECVKLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLSITLGRRGQYVMLSECLERAMKFAFGEFHLWYQVALSMVACGKSAYAVSLLRECVKLR 40 50 60 70 80 90 330 340 350 360 370 380 pF1KA1 PSDPTVPLMAAKVCIGSLRWLEEAEHFAMMVISLGEEAGEFLPKGYLALGLTYSLQATDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PSDPTVPLMAAKVCIGSLRWLEEAEHFAMMVISLGEEAGEFLPKGYLALGLTYSLQATDA 100 110 120 130 140 150 390 400 410 420 430 440 pF1KA1 TLKSKQDELHRKALQTLERAQQLAPSDPQVILYVSLQLALVRQISSAMEQLQEALKVRKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLKSKQDELHRKALQTLERAQQLAPSDPQVILYVSLQLALVRQISSAMEQLQEALKVRKD 160 170 180 190 200 210 450 460 470 480 490 500 pF1KA1 DAHALHLLALLFSAQKHHQHALDVVNMAITEHPENFNLIFTKVKLEQVLKGPEEALVTCR ::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::: NP_001 DAHALHLLALLFSAQKHHQHALDVVNMAITEHPENFNLMFTKVKLEQVLKGPEEALVTCR 220 230 240 250 260 270 510 520 530 540 550 560 pF1KA1 QVLRLWQTLYSFSQLGGLEKDGSFGEGLTMKKQSGMHLTLPDAHDADSGSRRASSIAASR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QVLRLWQTLYSFSQLGGLEKDGSFGEGLTMKKQSGMHLTLPDAHDADSGSRRASSIAASR 280 290 300 310 320 330 570 580 590 600 610 620 pF1KA1 LEEAMSELTMPSSVLKQGPMQLWTTLEQIWLQAAELFMEQQHLKEAGFCIQEAAGLFPTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LEEAMSELTMPSSVLKQGPMQLWTTLEQIWLQAAELFMEQQHLKEAGFCIQEAAGLFPTS 340 350 360 370 380 390 630 640 650 660 670 680 pF1KA1 HSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVLRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVLRD 400 410 420 430 440 450 690 700 710 720 730 pF1KA1 AVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELEASSPVLPFSIIPREL :::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELEASSPVLPFSIIPREL 460 470 480 490 500 739 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 20:34:51 2016 done: Wed Nov 2 20:34:52 2016 Total Scan time: 8.500 Total Display time: 0.150 Function used was FASTA [36.3.4 Apr, 2011]