Result of FASTA (omim) for
pF1KA1154
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA1154, 476 aa
1>>>pF1KA1154 476 - 476 aa - 476 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.1499+/-0.000403; mu= 5.1983+/- 0.025
mean_var=181.2483+/-36.683, 0's: 0 Z-trim(118.0): 35 B-trim: 1662 in 1/54
Lambda= 0.095266
statistics sampled from 30577 (30612) to 30577 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.697), E-opt: 0.2 (0.359), width: 16
Scan time: 10.830
The best scores are: opt bits E(85289)
NP_001182539 (OMIM: 605755,610212,610212,616217) d ( 476) 3093 437.6 3.6e-122
NP_057440 (OMIM: 605755,610212,610212,616217) doub ( 476) 3093 437.6 3.6e-122
XP_016876336 (OMIM: 604742) PREDICTED: serine/thre ( 708) 367 63.0 3e-09
NP_004725 (OMIM: 604742) serine/threonine-protein ( 729) 367 63.1 3.1e-09
NP_001317000 (OMIM: 604742) serine/threonine-prote ( 740) 367 63.1 3.1e-09
NP_001317001 (OMIM: 604742) serine/threonine-prote ( 740) 367 63.1 3.1e-09
XP_016876337 (OMIM: 604742) PREDICTED: serine/thre ( 363) 341 59.3 2.1e-08
NP_835366 (OMIM: 300067,300121) neuronal migration ( 360) 323 56.8 1.2e-07
NP_835364 (OMIM: 300067,300121) neuronal migration ( 360) 323 56.8 1.2e-07
XP_011529180 (OMIM: 300067,300121) PREDICTED: neur ( 361) 323 56.8 1.2e-07
NP_000546 (OMIM: 300067,300121) neuronal migration ( 441) 323 56.8 1.4e-07
XP_011529181 (OMIM: 300067,300121) PREDICTED: neur ( 324) 318 56.1 1.7e-07
XP_005262842 (OMIM: 613166) PREDICTED: serine/thre ( 782) 321 56.8 2.6e-07
XP_016863322 (OMIM: 613166) PREDICTED: serine/thre ( 694) 319 56.4 2.9e-07
XP_016863321 (OMIM: 613166) PREDICTED: serine/thre ( 717) 319 56.5 2.9e-07
NP_001035351 (OMIM: 613166) serine/threonine-prote ( 783) 319 56.5 3.2e-07
NP_835365 (OMIM: 300067,300121) neuronal migration ( 365) 308 54.7 5e-07
XP_016884801 (OMIM: 300067,300121) PREDICTED: neur ( 366) 308 54.7 5e-07
NP_001182482 (OMIM: 300067,300121) neuronal migrat ( 366) 308 54.7 5e-07
XP_011529182 (OMIM: 300067,300121) PREDICTED: neur ( 319) 306 54.4 5.4e-07
XP_005262843 (OMIM: 613166) PREDICTED: serine/thre ( 765) 312 55.5 6e-07
NP_001035350 (OMIM: 613166) serine/threonine-prote ( 766) 311 55.4 6.6e-07
XP_016869211 (OMIM: 180100,603937) PREDICTED: oxyg (2156) 303 54.6 3.2e-06
NP_006260 (OMIM: 180100,603937) oxygen-regulated p (2156) 303 54.6 3.2e-06
XP_016869210 (OMIM: 180100,603937) PREDICTED: oxyg (2163) 303 54.6 3.2e-06
NP_849188 (OMIM: 608581,613587) retinitis pigmento (2400) 240 46.0 0.0014
>>NP_001182539 (OMIM: 605755,610212,610212,616217) doubl (476 aa)
initn: 3093 init1: 3093 opt: 3093 Z-score: 2314.2 bits: 437.6 E(85289): 3.6e-122
Smith-Waterman score: 3093; 99.8% identity (100.0% similar) in 476 aa overlap (1-476:1-476)
10 20 30 40 50 60
pF1KA1 MSGSSARSSHLSQPVVKSVLVYRNGDPFYAGRRVVIHEKKVSSFEVFLKEVTGGVQAPFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSGSSARSSHLSQPVVKSVLVYRNGDPFYAGRRVVIHEKKVSSFEVFLKEVTGGVQAPFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 AVRNIYTPRTGHRIRKLDQIQSGGNYVAGGQEAFKKLNYLDIGEIKKRPMEVVNTEVKPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVRNIYTPRTGHRIRKLDQIQSGGNYVAGGQEAFKKLNYLDIGEIKKRPMEVVNTEVKPV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 IHSRINVSARFRKPLQEPCTIFLIANGDLINPASRLLIPRKTLNQWDHVLQMVTEKITLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IHSRINVSARFRKPLQEPCTIFLIANGDLINPASRLLIPRKTLNQWDHVLQMVTEKITLR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 SGAVHRLYTLEGKLVESGAELENGQFYVAVGRDKFKKLPYGELLFDKSTMRRPFGQKASS
::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::
NP_001 SGAVHRLYTLEGKLVESGAELENGQFYVAVGRDKFKKLPYSELLFDKSTMRRPFGQKASS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 LPPIVGSRKSKGSGNDRHSKSTVGSSDNSSPQPLKRKGKKEDVNSEKLTKLKQNVKLKNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPPIVGSRKSKGSGNDRHSKSTVGSSDNSSPQPLKRKGKKEDVNSEKLTKLKQNVKLKNS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 QETIPNSDEGIFKAGAERSETRGAAEVQEDEDTQVEVPVDQRPAEIVDEEEDGEKANKDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QETIPNSDEGIFKAGAERSETRGAAEVQEDEDTQVEVPVDQRPAEIVDEEEDGEKANKDA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 EQKEDFSGMNGDLEEEGGREATDAPEQVEEILDHSEQQARPARVNGGTDEENGEELQQVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EQKEDFSGMNGDLEEEGGREATDAPEQVEEILDHSEQQARPARVNGGTDEENGEELQQVN
370 380 390 400 410 420
430 440 450 460 470
pF1KA1 NELQLVLDKERKSQGAGSGQDEADVDPQRPPRPEVKITSPEENENNQQNKDYAAVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NELQLVLDKERKSQGAGSGQDEADVDPQRPPRPEVKITSPEENENNQQNKDYAAVA
430 440 450 460 470
>>NP_057440 (OMIM: 605755,610212,610212,616217) doubleco (476 aa)
initn: 3093 init1: 3093 opt: 3093 Z-score: 2314.2 bits: 437.6 E(85289): 3.6e-122
Smith-Waterman score: 3093; 99.8% identity (100.0% similar) in 476 aa overlap (1-476:1-476)
10 20 30 40 50 60
pF1KA1 MSGSSARSSHLSQPVVKSVLVYRNGDPFYAGRRVVIHEKKVSSFEVFLKEVTGGVQAPFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MSGSSARSSHLSQPVVKSVLVYRNGDPFYAGRRVVIHEKKVSSFEVFLKEVTGGVQAPFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 AVRNIYTPRTGHRIRKLDQIQSGGNYVAGGQEAFKKLNYLDIGEIKKRPMEVVNTEVKPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 AVRNIYTPRTGHRIRKLDQIQSGGNYVAGGQEAFKKLNYLDIGEIKKRPMEVVNTEVKPV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 IHSRINVSARFRKPLQEPCTIFLIANGDLINPASRLLIPRKTLNQWDHVLQMVTEKITLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 IHSRINVSARFRKPLQEPCTIFLIANGDLINPASRLLIPRKTLNQWDHVLQMVTEKITLR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 SGAVHRLYTLEGKLVESGAELENGQFYVAVGRDKFKKLPYGELLFDKSTMRRPFGQKASS
::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::
NP_057 SGAVHRLYTLEGKLVESGAELENGQFYVAVGRDKFKKLPYSELLFDKSTMRRPFGQKASS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 LPPIVGSRKSKGSGNDRHSKSTVGSSDNSSPQPLKRKGKKEDVNSEKLTKLKQNVKLKNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 LPPIVGSRKSKGSGNDRHSKSTVGSSDNSSPQPLKRKGKKEDVNSEKLTKLKQNVKLKNS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 QETIPNSDEGIFKAGAERSETRGAAEVQEDEDTQVEVPVDQRPAEIVDEEEDGEKANKDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 QETIPNSDEGIFKAGAERSETRGAAEVQEDEDTQVEVPVDQRPAEIVDEEEDGEKANKDA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 EQKEDFSGMNGDLEEEGGREATDAPEQVEEILDHSEQQARPARVNGGTDEENGEELQQVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 EQKEDFSGMNGDLEEEGGREATDAPEQVEEILDHSEQQARPARVNGGTDEENGEELQQVN
370 380 390 400 410 420
430 440 450 460 470
pF1KA1 NELQLVLDKERKSQGAGSGQDEADVDPQRPPRPEVKITSPEENENNQQNKDYAAVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 NELQLVLDKERKSQGAGSGQDEADVDPQRPPRPEVKITSPEENENNQQNKDYAAVA
430 440 450 460 470
>>XP_016876336 (OMIM: 604742) PREDICTED: serine/threonin (708 aa)
initn: 277 init1: 123 opt: 367 Z-score: 287.0 bits: 63.0 E(85289): 3e-09
Smith-Waterman score: 367; 30.6% identity (56.9% similar) in 353 aa overlap (12-342:52-389)
10 20 30 40
pF1KA1 MSGSSARSSHLSQPVVKSVLVYRNGDPFYAGRRVVIHEKKV
:. .:.: ::::: .. : .: .
XP_016 SRGSRVNGLPSPTHSAHCSFYRTRTLQTLSSEKKAKKVRFYRNGDRYFKGIVYAISPDRF
30 40 50 60 70 80
50 60 70 80 90
pF1KA1 SSFEVFLKEVT----GGVQAPFGAVRNIYTPRTGHRIRKLDQIQSGGNYVAGGQEAFKKL
:::..: ..: .:. : : ::.::: ..: .:::. : .:: :. : ::::
XP_016 RSFEALLADLTRTLSDNVNLPQG-VRTIYTIDGLKKISSLDQLVEGESYVCGSIEPFKKL
90 100 110 120 130 140
100 110 120 130 140
pF1KA1 NYLDIGEIKKRPMEVVNTEVKPVIHSRINVS----------ARFRKPLQEPCTIFLIANG
.: . : :: :: . :: : .: : . .: . .: .:
XP_016 EYTK----NVNPNWSVN--VKTTSASRAVSSLATAKGSPSEVRENKDFIRPKLVTIIRSG
150 160 170 180 190
150 160 170 180 190 200
pF1KA1 DLINPASRLLIPRKTLNQWDHVLQMVTEKITLRSGAVHRLYTLEGKLVESGAELE-NGQF
: :.:. .:: .....:: .:. : : ::.:.:::::.:: : .. . ..
XP_016 VKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVKRLYTLDGKQVMCLQDFFGDDDI
200 210 220 230 240 250
210 220 230 240 250 260
pF1KA1 YVAVGRDKFKKLPYGELLFDKSTMRRPFGQKASSLPPIVGS-RKS--KGSGNDRHSKSTV
..: : .::. ..:.:.: : :..: :..: :.: :. : .:.::: .
XP_016 FIACGPEKFRY--QDDFLLDESECRV---VKSTSYTKIASSSRRSTTKSPGPSRRSKSPA
260 270 280 290 300
270 280 290 300 310
pF1KA1 GSSD-NSSPQP---LKRKGKKEDVNSEKLTKLKQNVKLKNSQETIPNSDEGIFKAGAERS
..:. :..: :.::. . . . .:. : ..::. ... . :. . .
XP_016 STSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLR---KQRSSQHGGSSTSLASTKVCSSMD
310 320 330 340 350 360
320 330 340 350 360 370
pF1KA1 ETRGAAEVQEDEDTQVEVPVDQRPAEIVDEEEDGEKANKDAEQKEDFSGMNGDLEEEGGR
:. : .: .: :. . . .:
XP_016 ENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKC
370 380 390 400 410 420
>>NP_004725 (OMIM: 604742) serine/threonine-protein kina (729 aa)
initn: 277 init1: 123 opt: 367 Z-score: 286.8 bits: 63.1 E(85289): 3.1e-09
Smith-Waterman score: 367; 30.6% identity (56.9% similar) in 353 aa overlap (12-342:52-389)
10 20 30 40
pF1KA1 MSGSSARSSHLSQPVVKSVLVYRNGDPFYAGRRVVIHEKKV
:. .:.: ::::: .. : .: .
NP_004 SRGSRVNGLPSPTHSAHCSFYRTRTLQTLSSEKKAKKVRFYRNGDRYFKGIVYAISPDRF
30 40 50 60 70 80
50 60 70 80 90
pF1KA1 SSFEVFLKEVT----GGVQAPFGAVRNIYTPRTGHRIRKLDQIQSGGNYVAGGQEAFKKL
:::..: ..: .:. : : ::.::: ..: .:::. : .:: :. : ::::
NP_004 RSFEALLADLTRTLSDNVNLPQG-VRTIYTIDGLKKISSLDQLVEGESYVCGSIEPFKKL
90 100 110 120 130 140
100 110 120 130 140
pF1KA1 NYLDIGEIKKRPMEVVNTEVKPVIHSRINVS----------ARFRKPLQEPCTIFLIANG
.: . : :: :: . :: : .: : . .: . .: .:
NP_004 EYTK----NVNPNWSVN--VKTTSASRAVSSLATAKGSPSEVRENKDFIRPKLVTIIRSG
150 160 170 180 190
150 160 170 180 190 200
pF1KA1 DLINPASRLLIPRKTLNQWDHVLQMVTEKITLRSGAVHRLYTLEGKLVESGAELE-NGQF
: :.:. .:: .....:: .:. : : ::.:.:::::.:: : .. . ..
NP_004 VKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVKRLYTLDGKQVMCLQDFFGDDDI
200 210 220 230 240 250
210 220 230 240 250 260
pF1KA1 YVAVGRDKFKKLPYGELLFDKSTMRRPFGQKASSLPPIVGS-RKS--KGSGNDRHSKSTV
..: : .::. ..:.:.: : :..: :..: :.: :. : .:.::: .
NP_004 FIACGPEKFRY--QDDFLLDESECRV---VKSTSYTKIASSSRRSTTKSPGPSRRSKSPA
260 270 280 290 300
270 280 290 300 310
pF1KA1 GSSD-NSSPQP---LKRKGKKEDVNSEKLTKLKQNVKLKNSQETIPNSDEGIFKAGAERS
..:. :..: :.::. . . . .:. : ..::. ... . :. . .
NP_004 STSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLR---KQRSSQHGGSSTSLASTKVCSSMD
310 320 330 340 350 360
320 330 340 350 360 370
pF1KA1 ETRGAAEVQEDEDTQVEVPVDQRPAEIVDEEEDGEKANKDAEQKEDFSGMNGDLEEEGGR
:. : .: .: :. . . .:
NP_004 ENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKC
370 380 390 400 410 420
>>NP_001317000 (OMIM: 604742) serine/threonine-protein k (740 aa)
initn: 312 init1: 123 opt: 367 Z-score: 286.7 bits: 63.1 E(85289): 3.1e-09
Smith-Waterman score: 367; 30.6% identity (56.9% similar) in 353 aa overlap (12-342:52-389)
10 20 30 40
pF1KA1 MSGSSARSSHLSQPVVKSVLVYRNGDPFYAGRRVVIHEKKV
:. .:.: ::::: .. : .: .
NP_001 SRGSRVNGLPSPTHSAHCSFYRTRTLQTLSSEKKAKKVRFYRNGDRYFKGIVYAISPDRF
30 40 50 60 70 80
50 60 70 80 90
pF1KA1 SSFEVFLKEVT----GGVQAPFGAVRNIYTPRTGHRIRKLDQIQSGGNYVAGGQEAFKKL
:::..: ..: .:. : : ::.::: ..: .:::. : .:: :. : ::::
NP_001 RSFEALLADLTRTLSDNVNLPQG-VRTIYTIDGLKKISSLDQLVEGESYVCGSIEPFKKL
90 100 110 120 130 140
100 110 120 130 140
pF1KA1 NYLDIGEIKKRPMEVVNTEVKPVIHSRINVS----------ARFRKPLQEPCTIFLIANG
.: . : :: :: . :: : .: : . .: . .: .:
NP_001 EYTK----NVNPNWSVN--VKTTSASRAVSSLATAKGSPSEVRENKDFIRPKLVTIIRSG
150 160 170 180 190
150 160 170 180 190 200
pF1KA1 DLINPASRLLIPRKTLNQWDHVLQMVTEKITLRSGAVHRLYTLEGKLVESGAELE-NGQF
: :.:. .:: .....:: .:. : : ::.:.:::::.:: : .. . ..
NP_001 VKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVKRLYTLDGKQVMCLQDFFGDDDI
200 210 220 230 240 250
210 220 230 240 250 260
pF1KA1 YVAVGRDKFKKLPYGELLFDKSTMRRPFGQKASSLPPIVGS-RKS--KGSGNDRHSKSTV
..: : .::. ..:.:.: : :..: :..: :.: :. : .:.::: .
NP_001 FIACGPEKFRY--QDDFLLDESECRV---VKSTSYTKIASSSRRSTTKSPGPSRRSKSPA
260 270 280 290 300
270 280 290 300 310
pF1KA1 GSSD-NSSPQP---LKRKGKKEDVNSEKLTKLKQNVKLKNSQETIPNSDEGIFKAGAERS
..:. :..: :.::. . . . .:. : ..::. ... . :. . .
NP_001 STSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLR---KQRSSQHGGSSTSLASTKVCSSMD
310 320 330 340 350 360
320 330 340 350 360 370
pF1KA1 ETRGAAEVQEDEDTQVEVPVDQRPAEIVDEEEDGEKANKDAEQKEDFSGMNGDLEEEGGR
:. : .: .: :. . . .:
NP_001 ENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKC
370 380 390 400 410 420
>>NP_001317001 (OMIM: 604742) serine/threonine-protein k (740 aa)
initn: 312 init1: 123 opt: 367 Z-score: 286.7 bits: 63.1 E(85289): 3.1e-09
Smith-Waterman score: 367; 30.6% identity (56.9% similar) in 353 aa overlap (12-342:52-389)
10 20 30 40
pF1KA1 MSGSSARSSHLSQPVVKSVLVYRNGDPFYAGRRVVIHEKKV
:. .:.: ::::: .. : .: .
NP_001 SRGSRVNGLPSPTHSAHCSFYRTRTLQTLSSEKKAKKVRFYRNGDRYFKGIVYAISPDRF
30 40 50 60 70 80
50 60 70 80 90
pF1KA1 SSFEVFLKEVT----GGVQAPFGAVRNIYTPRTGHRIRKLDQIQSGGNYVAGGQEAFKKL
:::..: ..: .:. : : ::.::: ..: .:::. : .:: :. : ::::
NP_001 RSFEALLADLTRTLSDNVNLPQG-VRTIYTIDGLKKISSLDQLVEGESYVCGSIEPFKKL
90 100 110 120 130 140
100 110 120 130 140
pF1KA1 NYLDIGEIKKRPMEVVNTEVKPVIHSRINVS----------ARFRKPLQEPCTIFLIANG
.: . : :: :: . :: : .: : . .: . .: .:
NP_001 EYTK----NVNPNWSVN--VKTTSASRAVSSLATAKGSPSEVRENKDFIRPKLVTIIRSG
150 160 170 180 190
150 160 170 180 190 200
pF1KA1 DLINPASRLLIPRKTLNQWDHVLQMVTEKITLRSGAVHRLYTLEGKLVESGAELE-NGQF
: :.:. .:: .....:: .:. : : ::.:.:::::.:: : .. . ..
NP_001 VKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVKRLYTLDGKQVMCLQDFFGDDDI
200 210 220 230 240 250
210 220 230 240 250 260
pF1KA1 YVAVGRDKFKKLPYGELLFDKSTMRRPFGQKASSLPPIVGS-RKS--KGSGNDRHSKSTV
..: : .::. ..:.:.: : :..: :..: :.: :. : .:.::: .
NP_001 FIACGPEKFRY--QDDFLLDESECRV---VKSTSYTKIASSSRRSTTKSPGPSRRSKSPA
260 270 280 290 300
270 280 290 300 310
pF1KA1 GSSD-NSSPQP---LKRKGKKEDVNSEKLTKLKQNVKLKNSQETIPNSDEGIFKAGAERS
..:. :..: :.::. . . . .:. : ..::. ... . :. . .
NP_001 STSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLR---KQRSSQHGGSSTSLASTKVCSSMD
310 320 330 340 350 360
320 330 340 350 360 370
pF1KA1 ETRGAAEVQEDEDTQVEVPVDQRPAEIVDEEEDGEKANKDAEQKEDFSGMNGDLEEEGGR
:. : .: .: :. . . .:
NP_001 ENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKC
370 380 390 400 410 420
>>XP_016876337 (OMIM: 604742) PREDICTED: serine/threonin (363 aa)
initn: 299 init1: 123 opt: 341 Z-score: 271.7 bits: 59.3 E(85289): 2.1e-08
Smith-Waterman score: 341; 33.7% identity (58.4% similar) in 279 aa overlap (12-271:52-318)
10 20 30 40
pF1KA1 MSGSSARSSHLSQPVVKSVLVYRNGDPFYAGRRVVIHEKKV
:. .:.: ::::: .. : .: .
XP_016 SRGSRVNGLPSPTHSAHCSFYRTRTLQTLSSEKKAKKVRFYRNGDRYFKGIVYAISPDRF
30 40 50 60 70 80
50 60 70 80 90
pF1KA1 SSFEVFLKEVT----GGVQAPFGAVRNIYTPRTGHRIRKLDQIQSGGNYVAGGQEAFKKL
:::..: ..: .:. : : ::.::: ..: .:::. : .:: :. : ::::
XP_016 RSFEALLADLTRTLSDNVNLPQG-VRTIYTIDGLKKISSLDQLVEGESYVCGSIEPFKKL
90 100 110 120 130 140
100 110 120 130 140
pF1KA1 NYLDIGEIKKRPMEVVNTEVKPVIHSRINVS----------ARFRKPLQEPCTIFLIANG
.: . : :: :: . :: : .: : . .: . .: .:
XP_016 EYTK----NVNPNWSVN--VKTTSASRAVSSLATAKGSPSEVRENKDFIRPKLVTIIRSG
150 160 170 180 190
150 160 170 180 190 200
pF1KA1 DLINPASRLLIPRKTLNQWDHVLQMVTEKITLRSGAVHRLYTLEGKLVESGAELE-NGQF
: :.:. .:: .....:: .:. : : ::.:.:::::.:: : .. . ..
XP_016 VKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVKRLYTLDGKQVMCLQDFFGDDDI
200 210 220 230 240 250
210 220 230 240 250 260
pF1KA1 YVAVGRDKFKKLPYGELLFDKSTMRRPFGQKASSLPPIVGS-RKS--KGSGNDRHSKSTV
..: : .::. ..:.:.: : :..: :..: :.: :. : .:.::: .
XP_016 FIACGPEKFRY--QDDFLLDESECRVV---KSTSYTKIASSSRRSTTKSPGPSRRSKSPA
260 270 280 290 300
270 280 290 300 310 320
pF1KA1 GSSD-NSSPQPLKRKGKKEDVNSEKLTKLKQNVKLKNSQETIPNSDEGIFKAGAERSETR
..:. :..:
XP_016 STSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLRKQRDLYRPLSSDDLDSVGDSV
310 320 330 340 350 360
>>NP_835366 (OMIM: 300067,300121) neuronal migration pro (360 aa)
initn: 239 init1: 102 opt: 323 Z-score: 258.4 bits: 56.8 E(85289): 1.2e-07
Smith-Waterman score: 323; 27.4% identity (61.9% similar) in 281 aa overlap (17-285:53-331)
10 20 30 40
pF1KA1 MSGSSARSSHLSQPVVKSVLVYRNGDPFYAGRRVVIHEKKVSSFEV
:.: ::::: .. : .. . ::..
NP_835 MNGLPSPTHSAHCSFYRTRTLQALSNEKKAKKVRFYRNGDRYFKGIVYAVSSDRFRSFDA
30 40 50 60 70 80
50 60 70 80 90 100
pF1KA1 FLKEVT----GGVQAPFGAVRNIYTPRTGHRIRKLDQIQSGGNYVAGGQEAFKKLNYL-D
.: ..: ... : : :: ::: ...: ..:... : .:: .... :::..: .
NP_835 LLADLTRSLSDNINLPQG-VRYIYTIDGSRKIGSMDELEEGESYVCSSDNFFKKVEYTKN
90 100 110 120 130 140
110 120 130 140 150 160
pF1KA1 IGEIKKRPMEV-VNTEVKPVIHSRINVSARFRKPLQEPCTIFLIANGDLINPASRLLIPR
.. . ... .: .. . : ...:: : . .: . .: .: : :.:. .
NP_835 VNPNWSVNVKTSANMKAPQSLASSNSAQARENKDFVRPKLVTIIRSGVKPRKAVRVLLNK
150 160 170 180 190 200
170 180 190 200 210
pF1KA1 KTLNQWDHVLQMVTEKITLRSGAVHRLYTLEGKLVESGAELE-NGQFYVAVGRDKFKKLP
:: .....:: .:: : :..:.:..::::.:: : .. . . ..: : .::.
NP_835 KTAHSFEQVLTDITEAIKLETGVVKKLYTLDGKQVTCLHDFFGDDDVFIACGPEKFR-YA
210 220 230 240 250 260
220 230 240 250 260 270
pF1KA1 YGELLFDKSTMRRPFGQ-KASSLP---PIVGSRKSKGSGNDRHSKSTVGSSDNSSPQPLK
.. .:.. : :. .:.. : : . ..:. : :.::: . :....: . :.
NP_835 QDDFSLDENECRVMKGNPSATAGPKASPTPQKTSAKSPGPMRRSKSPADSANGTSSSQLS
270 280 290 300 310 320
280 290 300 310 320 330
pF1KA1 R-KGKKEDVNSEKLTKLKQNVKLKNSQETIPNSDEGIFKAGAERSETRGAAEVQEDEDTQ
:.:. ...
NP_835 TPKSKQSPISTPTSPGSLRKHKDLYLPLSLDDSDSLGDSM
330 340 350 360
>>NP_835364 (OMIM: 300067,300121) neuronal migration pro (360 aa)
initn: 239 init1: 102 opt: 323 Z-score: 258.4 bits: 56.8 E(85289): 1.2e-07
Smith-Waterman score: 323; 27.4% identity (61.9% similar) in 281 aa overlap (17-285:53-331)
10 20 30 40
pF1KA1 MSGSSARSSHLSQPVVKSVLVYRNGDPFYAGRRVVIHEKKVSSFEV
:.: ::::: .. : .. . ::..
NP_835 MNGLPSPTHSAHCSFYRTRTLQALSNEKKAKKVRFYRNGDRYFKGIVYAVSSDRFRSFDA
30 40 50 60 70 80
50 60 70 80 90 100
pF1KA1 FLKEVT----GGVQAPFGAVRNIYTPRTGHRIRKLDQIQSGGNYVAGGQEAFKKLNYL-D
.: ..: ... : : :: ::: ...: ..:... : .:: .... :::..: .
NP_835 LLADLTRSLSDNINLPQG-VRYIYTIDGSRKIGSMDELEEGESYVCSSDNFFKKVEYTKN
90 100 110 120 130 140
110 120 130 140 150 160
pF1KA1 IGEIKKRPMEV-VNTEVKPVIHSRINVSARFRKPLQEPCTIFLIANGDLINPASRLLIPR
.. . ... .: .. . : ...:: : . .: . .: .: : :.:. .
NP_835 VNPNWSVNVKTSANMKAPQSLASSNSAQARENKDFVRPKLVTIIRSGVKPRKAVRVLLNK
150 160 170 180 190 200
170 180 190 200 210
pF1KA1 KTLNQWDHVLQMVTEKITLRSGAVHRLYTLEGKLVESGAELE-NGQFYVAVGRDKFKKLP
:: .....:: .:: : :..:.:..::::.:: : .. . . ..: : .::.
NP_835 KTAHSFEQVLTDITEAIKLETGVVKKLYTLDGKQVTCLHDFFGDDDVFIACGPEKFR-YA
210 220 230 240 250 260
220 230 240 250 260 270
pF1KA1 YGELLFDKSTMRRPFGQ-KASSLP---PIVGSRKSKGSGNDRHSKSTVGSSDNSSPQPLK
.. .:.. : :. .:.. : : . ..:. : :.::: . :....: . :.
NP_835 QDDFSLDENECRVMKGNPSATAGPKASPTPQKTSAKSPGPMRRSKSPADSANGTSSSQLS
270 280 290 300 310 320
280 290 300 310 320 330
pF1KA1 R-KGKKEDVNSEKLTKLKQNVKLKNSQETIPNSDEGIFKAGAERSETRGAAEVQEDEDTQ
:.:. ...
NP_835 TPKSKQSPISTPTSPGSLRKHKDLYLPLSLDDSDSLGDSM
330 340 350 360
>>XP_011529180 (OMIM: 300067,300121) PREDICTED: neuronal (361 aa)
initn: 239 init1: 102 opt: 323 Z-score: 258.4 bits: 56.8 E(85289): 1.2e-07
Smith-Waterman score: 323; 27.4% identity (61.9% similar) in 281 aa overlap (17-285:53-331)
10 20 30 40
pF1KA1 MSGSSARSSHLSQPVVKSVLVYRNGDPFYAGRRVVIHEKKVSSFEV
:.: ::::: .. : .. . ::..
XP_011 MNGLPSPTHSAHCSFYRTRTLQALSNEKKAKKVRFYRNGDRYFKGIVYAVSSDRFRSFDA
30 40 50 60 70 80
50 60 70 80 90 100
pF1KA1 FLKEVT----GGVQAPFGAVRNIYTPRTGHRIRKLDQIQSGGNYVAGGQEAFKKLNYL-D
.: ..: ... : : :: ::: ...: ..:... : .:: .... :::..: .
XP_011 LLADLTRSLSDNINLPQG-VRYIYTIDGSRKIGSMDELEEGESYVCSSDNFFKKVEYTKN
90 100 110 120 130 140
110 120 130 140 150 160
pF1KA1 IGEIKKRPMEV-VNTEVKPVIHSRINVSARFRKPLQEPCTIFLIANGDLINPASRLLIPR
.. . ... .: .. . : ...:: : . .: . .: .: : :.:. .
XP_011 VNPNWSVNVKTSANMKAPQSLASSNSAQARENKDFVRPKLVTIIRSGVKPRKAVRVLLNK
150 160 170 180 190 200
170 180 190 200 210
pF1KA1 KTLNQWDHVLQMVTEKITLRSGAVHRLYTLEGKLVESGAELE-NGQFYVAVGRDKFKKLP
:: .....:: .:: : :..:.:..::::.:: : .. . . ..: : .::.
XP_011 KTAHSFEQVLTDITEAIKLETGVVKKLYTLDGKQVTCLHDFFGDDDVFIACGPEKFR-YA
210 220 230 240 250 260
220 230 240 250 260 270
pF1KA1 YGELLFDKSTMRRPFGQ-KASSLP---PIVGSRKSKGSGNDRHSKSTVGSSDNSSPQPLK
.. .:.. : :. .:.. : : . ..:. : :.::: . :....: . :.
XP_011 QDDFSLDENECRVMKGNPSATAGPKASPTPQKTSAKSPGPMRRSKSPADSANGTSSSQLS
270 280 290 300 310 320
280 290 300 310 320 330
pF1KA1 R-KGKKEDVNSEKLTKLKQNVKLKNSQETIPNSDEGIFKAGAERSETRGAAEVQEDEDTQ
:.:. ...
XP_011 TPKSKQSPISTPTSPGSLRKHKVDLYLPLSLDDSDSLGDSM
330 340 350 360
476 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 20:39:11 2016 done: Wed Nov 2 20:39:12 2016
Total Scan time: 10.830 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]