Result of FASTA (omim) for
pF1KA1159
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA1159, 252 aa
1>>>pF1KA1159 252 - 252 aa - 252 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.8409+/-0.000288; mu= 9.0028+/- 0.018
mean_var=129.9989+/-26.781, 0's: 0 Z-trim(122.3): 6 B-trim: 1439 in 1/53
Lambda= 0.112488
statistics sampled from 40332 (40338) to 40332 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.805), E-opt: 0.2 (0.473), width: 16
Scan time: 7.530
The best scores are: opt bits E(85289)
NP_009156 (OMIM: 604636) neurexophilin-3 precursor ( 252) 1794 301.4 1e-81
NP_689958 (OMIM: 604639) neurexophilin-1 precursor ( 271) 847 147.7 1.9e-35
NP_009157 (OMIM: 604635) neurexophilin-2 precursor ( 264) 815 142.5 7e-34
NP_009155 (OMIM: 604637) neurexophilin-4 precursor ( 308) 375 71.2 2.5e-12
XP_016874236 (OMIM: 604637) PREDICTED: neurexophil ( 223) 182 39.8 0.0051
>>NP_009156 (OMIM: 604636) neurexophilin-3 precursor [Ho (252 aa)
initn: 1794 init1: 1794 opt: 1794 Z-score: 1588.2 bits: 301.4 E(85289): 1e-81
Smith-Waterman score: 1794; 100.0% identity (100.0% similar) in 252 aa overlap (1-252:1-252)
10 20 30 40 50 60
pF1KA1 MQLTRCCFVFLVQGSLYLVICGQDDGPPGSEDPERDDHEGQPRPRVPRKRGHISPKSRPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 MQLTRCCFVFLVQGSLYLVICGQDDGPPGSEDPERDDHEGQPRPRVPRKRGHISPKSRPM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 ANSTLLGLLAPPGEAWGILGQPPNRPNHSPPPSAKVKKIFGWGDFYSNIKTVALNLLVTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 ANSTLLGLLAPPGEAWGILGQPPNRPNHSPPPSAKVKKIFGWGDFYSNIKTVALNLLVTG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 KIVDHGNGTFSVHFQHNATGQGNISISLVPPSKAVEFHQEQQIFIEAKASKIFNCRMEWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 KIVDHGNGTFSVHFQHNATGQGNISISLVPPSKAVEFHQEQQIFIEAKASKIFNCRMEWE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 KVERGRRTSLCTHDPAKICSRDHAQSSATWSCSQPFKVVCVYIAFYSTDYRLVQKVCPDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 KVERGRRTSLCTHDPAKICSRDHAQSSATWSCSQPFKVVCVYIAFYSTDYRLVQKVCPDY
190 200 210 220 230 240
250
pF1KA1 NYHSDTPYYPSG
::::::::::::
NP_009 NYHSDTPYYPSG
250
>>NP_689958 (OMIM: 604639) neurexophilin-1 precursor [Ho (271 aa)
initn: 906 init1: 838 opt: 847 Z-score: 757.2 bits: 147.7 E(85289): 1.9e-35
Smith-Waterman score: 847; 65.1% identity (86.9% similar) in 175 aa overlap (79-252:97-271)
50 60 70 80 90 100
pF1KA1 KRGHISPKSRPMANSTLLGLLAPPGEAWGILGQPPNRPNHSPP-PSAKVKKIFGWGDFYS
: .: : .. : ..: ::.::::::.:
NP_689 ENDTDLDLRYDTPEPYSEQDLWDWLRNSTDLQEPRPRAKRRPIVKTGKFKKMFGWGDFHS
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA1 NIKTVALNLLVTGKIVDHGNGTFSVHFQHNATGQGNISISLVPPSKAVEFHQEQQIFIEA
::::: ::::.::::::::::::::.:.::.:::::.:.:::::.: ::: :: :.:
NP_689 NIKTVKLNLLITGKIVDHGNGTFSVYFRHNSTGQGNVSVSLVPPTKIVEFDLAQQTVIDA
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA1 KASKIFNCRMEWEKVERGRRTSLCTHDPAKICSRDHAQSSATWSCSQPFKVVCVYIAFYS
: :: ::::.:.:::... ...::..::.: : ....:: ..: ::.::::.:.::.:::
NP_689 KDSKSFNCRIEYEKVDKATKNTLCNYDPSKTCYQEQTQSHVSWLCSKPFKVICIYISFYS
190 200 210 220 230 240
230 240 250
pF1KA1 TDYRLVQKVCPDYNYHSDTPYYPSG
:::.:::::::::::::::::.:::
NP_689 TDYKLVQKVCPDYNYHSDTPYFPSG
250 260 270
>>NP_009157 (OMIM: 604635) neurexophilin-2 precursor [Ho (264 aa)
initn: 826 init1: 806 opt: 815 Z-score: 729.3 bits: 142.5 E(85289): 7e-34
Smith-Waterman score: 822; 50.8% identity (72.3% similar) in 256 aa overlap (11-252:10-264)
10 20 30 40 50
pF1KA1 MQLTRCCFVFLVQGSLYLVICGQDDGPPGSE--DPERDDHEGQPRPRVPRKRGHISP---
.: : : :..: . . ..: : : : : : ..: :::
NP_009 MRLRPLPLVVVPGLLQLLFCDSKEVVHATEGLDWEDKDAPGTLVGNVVHSRI-ISPLRL
10 20 30 40 50
60 70 80 90 100
pF1KA1 --KSRPMANSTLLGLLAPPGEAWGILG------QPPNRPNHSPP-PSAKVKKIFGWGDFY
:. :. . .. . : :. .: : .. : ..: ::.::::::.
NP_009 FVKQSPVPKPGPMAYADSMENFWDWLANITEIQEPLARTKRRPIVKTGKFKKMFGWGDFH
60 70 80 90 100 110
110 120 130 140 150 160
pF1KA1 SNIKTVALNLLVTGKIVDHGNGTFSVHFQHNATGQGNISISLVPPSKAVEFHQEQQIFIE
:::::: ::::.::::::::::::::.:.::.:: ::.:.:::::::.:::. : .:
NP_009 SNIKTVKLNLLITGKIVDHGNGTFSVYFRHNSTGLGNVSVSLVPPSKVVEFEVSPQSTLE
120 130 140 150 160 170
170 180 190 200 210 220
pF1KA1 AKASKIFNCRMEWEKVERGRRTSLCTHDPAKICSRDHAQSSATWSCSQPFKVVCVYIAFY
.: :: ::::.:.::..:...:.::. ::.::: ....:: ..: ::.::::.:.:::::
NP_009 TKESKSFNCRIEYEKTDRAKKTALCNFDPSKICYQEQTQSHVSWLCSKPFKVICIYIAFY
180 190 200 210 220 230
230 240 250
pF1KA1 STDYRLVQKVCPDYNYHSDTPYYPSG
:.::.:::::::::::::.::: ::
NP_009 SVDYKLVQKVCPDYNYHSETPYLSSG
240 250 260
>>NP_009155 (OMIM: 604637) neurexophilin-4 precursor [Ho (308 aa)
initn: 693 init1: 375 opt: 375 Z-score: 342.5 bits: 71.2 E(85289): 2.5e-12
Smith-Waterman score: 598; 39.7% identity (59.9% similar) in 277 aa overlap (26-249:44-307)
10 20 30 40 50
pF1KA1 MQLTRCCFVFLVQGSLYLVICGQDDGPPGSEDPERDDHEGQPRPRVPRKRGHISP
: ::.. :: :: :.
NP_009 PWLLRKAVSAQIPESGRPQYLGLRPAAAGAGAPGQQLPE-------PRSSDGLGVGRAWS
20 30 40 50 60
60 70 80 90 100 110
pF1KA1 KSRPMANSTLLGLLAPPGEAWGILGQPPNRPNHSPP-PSAKVKKIFGWGDFYSNIKTVAL
. : .: : : :: : : : : : .: ...: .:..:::::::::: ..:. .
NP_009 WAWP-TNHT--GALARAGAA-GAL--PAQRTKRKPSIKAARAKKIFGWGDFYFRVHTLKF
70 80 90 100 110 120
120 130 140 150 160
pF1KA1 NLLVTGKIVDHGNGTFSVHFQHNATGQGNISISLVPPSKAVEF----------HQEQQIF
.:::::::::: ::::::.:.::... ::.:.:.::::: ::: : :. .
NP_009 SLLVTGKIVDHVNGTFSVYFRHNSSSLGNLSVSIVPPSKRVEFGGVWLPGPVPHPLQSTL
130 140 150 160 170 180
170 180
pF1KA1 -IE-----------------------------------------AKASKIFNCRMEWEKV
.: :: :. :::..:.::.
NP_009 ALEGVLPGLGPPLGMAAAAAGPGLGGSLGGALAGPLGGALGVPGAKESRAFNCHVEYEKT
190 200 210 220 230 240
190 200 210 220 230 240
pF1KA1 ERGRRTSLCTHDPAKICSRDHAQSSATWSCSQPFKVVCVYIAFYSTDYRLVQKVCPDYNY
.:.:. : .::...: .:.::.:.: :..::::.:....: : ::.::::::::::.
NP_009 NRARKHRPCLYDPSQVCFTEHTQSQAAWLCAKPFKVICIFVSFLSFDYKLVQKVCPDYNF
250 260 270 280 290 300
250
pF1KA1 HSDTPYYPSG
.:. ::.
NP_009 QSEHPYFG
>>XP_016874236 (OMIM: 604637) PREDICTED: neurexophilin-4 (223 aa)
initn: 177 init1: 152 opt: 182 Z-score: 175.1 bits: 39.8 E(85289): 0.0051
Smith-Waterman score: 190; 40.8% identity (58.3% similar) in 103 aa overlap (26-127:44-133)
10 20 30 40 50
pF1KA1 MQLTRCCFVFLVQGSLYLVICGQDDGPPGSEDPERDDHEGQPRPRVPRKRGHISP
: ::.. :: :: :.
XP_016 PWLLRKAVSAQIPESGRPQYLGLRPAAAGAGAPGQQLPE-------PRSSDGLGVGRAWS
20 30 40 50 60
60 70 80 90 100 110
pF1KA1 KSRPMANSTLLGLLAPPGEAWGILGQPPNRPNHSPP-PSAKVKKIFGWGDFYSNIKTVAL
. : .. : :: : : : : : .: ...: .:..:::::::::: ..:. .
XP_016 WAWPTNHT---GALARAGAA-GAL--PAQRTKRKPSIKAARAKKIFGWGDFYFRVHTLKF
70 80 90 100 110 120
120 130 140 150 160 170
pF1KA1 NLLVTGKIVDHGNGTFSVHFQHNATGQGNISISLVPPSKAVEFHQEQQIFIEAKASKIFN
.:::::::::: :
XP_016 SLLVTGKIVDHVNALTTNWCRRCAQTITSRVSTPTSDSAPPQPVLSLPPNPSLTRWDPLP
130 140 150 160 170 180
252 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 19:54:01 2016 done: Thu Nov 3 19:54:03 2016
Total Scan time: 7.530 Total Display time: -0.030
Function used was FASTA [36.3.4 Apr, 2011]