FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA1160, 331 aa
  1>>>pF1KA1160 331 - 331 aa - 331 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.7712+/-0.000307; mu= 6.2704+/- 0.019
 mean_var=175.9670+/-34.414, 0's: 0 Z-trim(122.7): 7  B-trim: 0 in 0/56
 Lambda= 0.096685
 statistics sampled from 41372 (41382) to 41372 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.803), E-opt: 0.2 (0.485), width:  16
 Scan time:  7.420

The best scores are:                                      opt bits E(85289)
NP_065752 (OMIM: 612764) pre-mRNA-splicing factor  ( 285) 1860 270.8 2.4e-72
NP_001186398 (OMIM: 612764) pre-mRNA-splicing fact ( 307)  931 141.3 2.5e-33


>>NP_065752 (OMIM: 612764) pre-mRNA-splicing factor ISY1  (285 aa)
 initn: 1860 init1: 1860 opt: 1860  Z-score: 1420.0  bits: 270.8 E(85289): 2.4e-72
Smith-Waterman score: 1860; 100.0% identity (100.0% similar) in 284 aa overlap (1-284:1-284)

               10        20        30        40        50        60
pF1KA1 MARNAEKAMTALARFRQAQLEEGKVKERRPFLASECTELPKAEKWRRQIIGEISKKVAQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MARNAEKAMTALARFRQAQLEEGKVKERRPFLASECTELPKAEKWRRQIIGEISKKVAQI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 QNAGLGEFRIRDLNDEINKLLREKGHWEVRIKELGGPDYGKVGPKMLDHEGKEVPGNRGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 QNAGLGEFRIRDLNDEINKLLREKGHWEVRIKELGGPDYGKVGPKMLDHEGKEVPGNRGY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 KYFGAAKDLPGVRELFEKEPLPPPRKTRAELMKAIDFEYYGYLDEDDGVIVPLEQEYEKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 KYFGAAKDLPGVRELFEKEPLPPPRKTRAELMKAIDFEYYGYLDEDDGVIVPLEQEYEKK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 LRAELVEKWKAEREARLARGEKEEEEEEEEEINIYAVTEEESDEEGSQEKGGDDSQQKFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LRAELVEKWKAEREARLARGEKEEEEEEEEEINIYAVTEEESDEEGSQEKGGDDSQQKFI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 AHVPVPSQQEIEEALVRRKKMELLQKYASETLQAQSEEARRLLGCRSGTRPARSGSAPSP
       ::::::::::::::::::::::::::::::::::::::::::::                
NP_065 AHVPVPSQQEIEEALVRRKKMELLQKYASETLQAQSEEARRLLGY               
              250       260       270       280                    

              310       320       330 
pF1KA1 RATTAVPMGPSLPTTSPRGAPSCRCLTGLRM

>>NP_001186398 (OMIM: 612764) pre-mRNA-splicing factor I  (307 aa)
 initn: 971 init1: 930 opt: 931  Z-score: 719.2  bits: 141.3 E(85289): 2.5e-33
Smith-Waterman score: 1796; 92.8% identity (92.8% similar) in 306 aa overlap (1-284:1-306)

               10        20        30        40        50        60
pF1KA1 MARNAEKAMTALARFRQAQLEEGKVKERRPFLASECTELPKAEKWRRQIIGEISKKVAQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MARNAEKAMTALARFRQAQLEEGKVKERRPFLASECTELPKAEKWRRQIIGEISKKVAQI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 QNAGLGEFRIRDLNDEINKLLREKGHWEVRIKELGGPDYGKVGPKMLDHEGKEVPGNRGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QNAGLGEFRIRDLNDEINKLLREKGHWEVRIKELGGPDYGKVGPKMLDHEGKEVPGNRGY
               70        80        90       100       110       120

              130              140                      150        
pF1KA1 KYFGAAKDLPGVRELFEKE-------P---------------LPPPRKTRAELMKAIDFE
       :::::::::::::::::::       :               ::::::::::::::::::
NP_001 KYFGAAKDLPGVRELFEKERQVRWLMPVIPALWEAEAGGSQALPPPRKTRAELMKAIDFE
              130       140       150       160       170       180

      160       170       180       190       200       210        
pF1KA1 YYGYLDEDDGVIVPLEQEYEKKLRAELVEKWKAEREARLARGEKEEEEEEEEEINIYAVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YYGYLDEDDGVIVPLEQEYEKKLRAELVEKWKAEREARLARGEKEEEEEEEEEINIYAVT
              190       200       210       220       230       240

      220       230       240       250       260       270        
pF1KA1 EEESDEEGSQEKGGDDSQQKFIAHVPVPSQQEIEEALVRRKKMELLQKYASETLQAQSEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEESDEEGSQEKGGDDSQQKFIAHVPVPSQQEIEEALVRRKKMELLQKYASETLQAQSEE
              250       260       270       280       290       300

      280       290       300       310       320       330 
pF1KA1 ARRLLGCRSGTRPARSGSAPSPRATTAVPMGPSLPTTSPRGAPSCRCLTGLRM
       ::::::                                               
NP_001 ARRLLGY                                              
                                                            




331 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Wed Nov  2 20:39:53 2016 done: Wed Nov  2 20:39:54 2016
 Total Scan time:  7.420 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]