FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1179, 1749 aa 1>>>pF1KA1179 1749 - 1749 aa - 1749 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4275+/-0.000537; mu= 24.5253+/- 0.034 mean_var=80.9313+/-16.781, 0's: 0 Z-trim(106.7): 72 B-trim: 1190 in 2/50 Lambda= 0.142566 statistics sampled from 14705 (14777) to 14705 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.493), E-opt: 0.2 (0.173), width: 16 Scan time: 12.480 The best scores are: opt bits E(85289) NP_056477 (OMIM: 607386,615630,616394) intraflagel (1749) 11586 2394.5 0 XP_006712049 (OMIM: 607386,615630,616394) PREDICTE (1728) 11444 2365.3 0 XP_006712050 (OMIM: 607386,615630,616394) PREDICTE (1716) 10609 2193.6 0 XP_016859280 (OMIM: 607386,615630,616394) PREDICTE (1522) 10052 2079.0 0 XP_011531059 (OMIM: 607386,615630,616394) PREDICTE (1522) 10052 2079.0 0 XP_011531060 (OMIM: 607386,615630,616394) PREDICTE (1327) 8736 1808.3 0 XP_016859281 (OMIM: 607386,615630,616394) PREDICTE (1318) 8182 1694.3 0 XP_011531061 (OMIM: 607386,615630,616394) PREDICTE (1229) 8107 1678.9 0 XP_016859279 (OMIM: 607386,615630,616394) PREDICTE (1706) 8039 1665.0 0 XP_005264311 (OMIM: 607386,615630,616394) PREDICTE (1727) 8039 1665.0 0 XP_011531062 (OMIM: 607386,615630,616394) PREDICTE (1104) 7282 1509.1 0 XP_016859282 (OMIM: 607386,615630,616394) PREDICTE (1128) 7282 1509.1 0 XP_016859283 (OMIM: 607386,615630,616394) PREDICTE (1128) 7282 1509.1 0 XP_016859284 (OMIM: 607386,615630,616394) PREDICTE (1060) 7000 1451.1 0 NP_001304853 (OMIM: 608151,614376,614378,616307) W (1182) 208 54.2 8.6e-06 XP_016863990 (OMIM: 608151,614376,614378,616307) P (1182) 208 54.2 8.6e-06 NP_079408 (OMIM: 608151,614376,614378,616307) WD r (1342) 208 54.2 9.5e-06 XP_011512029 (OMIM: 608151,614376,614378,616307) P (1186) 197 51.9 4.2e-05 XP_011512028 (OMIM: 608151,614376,614378,616307) P (1186) 197 51.9 4.2e-05 XP_011512027 (OMIM: 608151,614376,614378,616307) P (1324) 197 52.0 4.5e-05 XP_011512026 (OMIM: 608151,614376,614378,616307) P (1346) 197 52.0 4.6e-05 XP_016862327 (OMIM: 218330,606045) PREDICTED: intr ( 773) 192 50.8 6.1e-05 XP_016862326 (OMIM: 218330,606045) PREDICTED: intr ( 800) 192 50.8 6.3e-05 XP_011511274 (OMIM: 218330,606045) PREDICTED: intr ( 975) 192 50.8 7.3e-05 NP_001267475 (OMIM: 218330,606045) intraflagellar (1032) 192 50.8 7.6e-05 XP_016862324 (OMIM: 218330,606045) PREDICTED: intr (1059) 192 50.9 7.8e-05 NP_001267474 (OMIM: 218330,606045) intraflagellar (1091) 192 50.9 7.9e-05 XP_016862320 (OMIM: 218330,606045) PREDICTED: intr (1118) 192 50.9 8.1e-05 XP_016862319 (OMIM: 218330,606045) PREDICTED: intr (1118) 192 50.9 8.1e-05 XP_016862321 (OMIM: 218330,606045) PREDICTED: intr (1118) 192 50.9 8.1e-05 XP_016862318 (OMIM: 218330,606045) PREDICTED: intr (1130) 192 50.9 8.2e-05 NP_443716 (OMIM: 218330,606045) intraflagellar tra (1131) 192 50.9 8.2e-05 XP_016862317 (OMIM: 218330,606045) PREDICTED: intr (1157) 192 50.9 8.3e-05 NP_060732 (OMIM: 218330,606045) intraflagellar tra (1182) 192 50.9 8.5e-05 XP_005247666 (OMIM: 218330,606045) PREDICTED: intr (1183) 192 50.9 8.5e-05 XP_016862313 (OMIM: 218330,606045) PREDICTED: intr (1208) 192 50.9 8.6e-05 XP_016862312 (OMIM: 218330,606045) PREDICTED: intr (1209) 192 50.9 8.6e-05 XP_016862311 (OMIM: 218330,606045) PREDICTED: intr (1216) 192 50.9 8.6e-05 NP_001267470 (OMIM: 218330,606045) intraflagellar (1234) 192 50.9 8.7e-05 NP_443715 (OMIM: 218330,606045) intraflagellar tra (1241) 192 50.9 8.8e-05 XP_006713752 (OMIM: 218330,606045) PREDICTED: intr (1242) 192 50.9 8.8e-05 XP_016862307 (OMIM: 218330,606045) PREDICTED: intr (1267) 192 50.9 8.9e-05 XP_016862306 (OMIM: 218330,606045) PREDICTED: intr (1268) 192 50.9 8.9e-05 NP_443711 (OMIM: 218330,606045) intraflagellar tra (1292) 192 50.9 9.1e-05 XP_016862325 (OMIM: 218330,606045) PREDICTED: intr (1015) 189 50.2 0.00012 XP_016862323 (OMIM: 218330,606045) PREDICTED: intr (1112) 189 50.3 0.00012 XP_016862322 (OMIM: 218330,606045) PREDICTED: intr (1113) 189 50.3 0.00012 XP_016862316 (OMIM: 218330,606045) PREDICTED: intr (1164) 189 50.3 0.00013 XP_006713755 (OMIM: 218330,606045) PREDICTED: intr (1165) 189 50.3 0.00013 XP_016862315 (OMIM: 218330,606045) PREDICTED: intr (1190) 189 50.3 0.00013 >>NP_056477 (OMIM: 607386,615630,616394) intraflagellar (1749 aa) initn: 11586 init1: 11586 opt: 11586 Z-score: 12870.2 bits: 2394.5 E(85289): 0 Smith-Waterman score: 11586; 100.0% identity (100.0% similar) in 1749 aa overlap (1-1749:1-1749) 10 20 30 40 50 60 pF1KA1 MHLKHLRTLLSPQDGAAKVTCMAWSQNNAKFAVCTVDRVVLLYDEHGERRDKFSTKPADM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 MHLKHLRTLLSPQDGAAKVTCMAWSQNNAKFAVCTVDRVVLLYDEHGERRDKFSTKPADM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 KYGRKSYMVKGMAFSPDSTKIAIGQTDNIIYVYKIGEDWGDKKVICNKFIQTSAVTCLQW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 KYGRKSYMVKGMAFSPDSTKIAIGQTDNIIYVYKIGEDWGDKKVICNKFIQTSAVTCLQW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 PAEYIIVFGLAEGKVRLANTKTNKSSTIYGTESYVVSLTTNCSGKGILSGHADGTIVRYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 PAEYIIVFGLAEGKVRLANTKTNKSSTIYGTESYVVSLTTNCSGKGILSGHADGTIVRYF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 FDDEGSGESQGKLVNHPCPPYALAWATNSIVAAGCDRKIVAYGKEGHMLQTFDYSRDPQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 FDDEGSGESQGKLVNHPCPPYALAWATNSIVAAGCDRKIVAYGKEGHMLQTFDYSRDPQE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 REFTTAVSSPGGQSVVLGSYDRLRVFNWIPRRSIWEEAKPKEITNLYTITALAWKRDGSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 REFTTAVSSPGGQSVVLGSYDRLRVFNWIPRRSIWEEAKPKEITNLYTITALAWKRDGSR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 LCVGTLCGGVEQFDCCLRRSIYKNKFELTYVGPSQVIVKNLSSGTRVVLKSHYGYEVEEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LCVGTLCGGVEQFDCCLRRSIYKNKFELTYVGPSQVIVKNLSSGTRVVLKSHYGYEVEEV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 KILGKERYLVAHTSETLLLGDLNTNRLSEIAWQGSGGNEKYFFENENVCMIFNAGELTLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 KILGKERYLVAHTSETLLLGDLNTNRLSEIAWQGSGGNEKYFFENENVCMIFNAGELTLV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 EYGNNDTLGSVRTEFMNPHLISVRINERCQRGTEDNKKLAYLIDIKTIAIVDLIGGYNIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 EYGNNDTLGSVRTEFMNPHLISVRINERCQRGTEDNKKLAYLIDIKTIAIVDLIGGYNIG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 TVSHESRVDWLELNETGHKLLFRDRKLRLHLYDIESCSKTMILNFCSYMQWVPGSDVLVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 TVSHESRVDWLELNETGHKLLFRDRKLRLHLYDIESCSKTMILNFCSYMQWVPGSDVLVA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 QNRNSLCVWYNIEAPERVTMFTIRGDVIGLERGGGKTEVMVMEGVTTVAYTLDEGLIEFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 QNRNSLCVWYNIEAPERVTMFTIRGDVIGLERGGGKTEVMVMEGVTTVAYTLDEGLIEFG 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 TAIDDGNYIRATAFLETLEMTPETEAMWKTLSKLALEARQLHIAERCFSALGQVAKARFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 TAIDDGNYIRATAFLETLEMTPETEAMWKTLSKLALEARQLHIAERCFSALGQVAKARFL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 HETNEIADQVSREYGGEGTDFYQVRARLAMLEKNYKLAEMIFLEQNAVEEAMGMYQELHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 HETNEIADQVSREYGGEGTDFYQVRARLAMLEKNYKLAEMIFLEQNAVEEAMGMYQELHR 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 WDECIAVAEAKGHPALEKLRRSYYQWLMDTQQEERAGELQESQGDGLAAISLYLKAGLPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 WDECIAVAEAKGHPALEKLRRSYYQWLMDTQQEERAGELQESQGDGLAAISLYLKAGLPA 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 KAARLVLTREELLANTELVEHITAALIKGELYERAGDLFEKIHNPQKALECYRKGNAFMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 KAARLVLTREELLANTELVEHITAALIKGELYERAGDLFEKIHNPQKALECYRKGNAFMK 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 AVELARLAFPVEVVKLEEAWGDHLVQQKQLDAAINHYIEARCSIKAIEAALGARQWKKAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 AVELARLAFPVEVVKLEEAWGDHLVQQKQLDAAINHYIEARCSIKAIEAALGARQWKKAI 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 YILDLQDRNTASKYYPLVAQHYASLQEYEIAEELYTKGDRTKDAIDMYTQAGRWEQAHKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 YILDLQDRNTASKYYPLVAQHYASLQEYEIAEELYTKGDRTKDAIDMYTQAGRWEQAHKL 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 AMKCMRPEDVSVLYITQAQEMEKQGKYREAERLYVTVQEPDLAITMYKKHKLYDDMIRLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 AMKCMRPEDVSVLYITQAQEMEKQGKYREAERLYVTVQEPDLAITMYKKHKLYDDMIRLV 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA1 GKHHPDLLSDTHLHLGKELEAEGRLQEAEYHYLEAQEWKATVNMYRASGLWEEAYRVART :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 GKHHPDLLSDTHLHLGKELEAEGRLQEAEYHYLEAQEWKATVNMYRASGLWEEAYRVART 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA1 QGGANAHKHVAYLWAKSLGGEAAVRLLNKLGLLEAAVDHAADNCSFEFAFELSRLALKHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 QGGANAHKHVAYLWAKSLGGEAAVRLLNKLGLLEAAVDHAADNCSFEFAFELSRLALKHK 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA1 TPEVHLKYAMFLEDEGKFEEAEAEFIRAGKPKEAVLMFVHNQDWEAAQRVAEAHDPDSVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 TPEVHLKYAMFLEDEGKFEEAEAEFIRAGKPKEAVLMFVHNQDWEAAQRVAEAHDPDSVA 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA1 EVLVGQARGALEEKDFQKAEGLLLRAQRPGLALNYYKEAGLWSDALRICKDYVPSQLEAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 EVLVGQARGALEEKDFQKAEGLLLRAQRPGLALNYYKEAGLWSDALRICKDYVPSQLEAL 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA1 QEEYEREATKKGARGVEGFVEQARHWEQAGEYSRAVDCYLKVRDSGNSGLAEKCWMKAAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 QEEYEREATKKGARGVEGFVEQARHWEQAGEYSRAVDCYLKVRDSGNSGLAEKCWMKAAE 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA1 LSIKFLPPQRNMEVVLAVGPQLIGIGKHSAAAELYLNLDLVKEAIDAFIEGEEWNKAKRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LSIKFLPPQRNMEVVLAVGPQLIGIGKHSAAAELYLNLDLVKEAIDAFIEGEEWNKAKRV 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA1 AKELDPRYEDYVDQHYKEFLKNQGKVDSLVGVDVIAALDLYVEQGQWDKCIETATKQNYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 AKELDPRYEDYVDQHYKEFLKNQGKVDSLVGVDVIAALDLYVEQGQWDKCIETATKQNYK 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA1 ILHKYVALYATHLIREGSSAQALALYVQHGAPANPQNFNIYKRIFTDMVSSPGTNCAEAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 ILHKYVALYATHLIREGSSAQALALYVQHGAPANPQNFNIYKRIFTDMVSSPGTNCAEAY 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA1 HSWADLRDVLFNLCENLVKSSEANSPAHEEFKTMLLIAHYYATRSAAQSVKQLETVAARL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 HSWADLRDVLFNLCENLVKSSEANSPAHEEFKTMLLIAHYYATRSAAQSVKQLETVAARL 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA1 SVSLLRHTQLLPVDKAFYEAGIAAKAVGWDNMAFIFLNRFLDLTDAIEEGTLDGLDHSDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 SVSLLRHTQLLPVDKAFYEAGIAAKAVGWDNMAFIFLNRFLDLTDAIEEGTLDGLDHSDF 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA1 QDTDIPFEVPLPAKQHVPEAEREEVRDWVLTVSMDQRLEQVLPRDERGAYEASLVAASTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 QDTDIPFEVPLPAKQHVPEAEREEVRDWVLTVSMDQRLEQVLPRDERGAYEASLVAASTG 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KA1 VRALPCLITGYPILRNKIEFKRPGKAANKDNWNKFLMAIKTSHSPVCQDVLKFISQWCGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 VRALPCLITGYPILRNKIEFKRPGKAANKDNWNKFLMAIKTSHSPVCQDVLKFISQWCGG 1690 1700 1710 1720 1730 1740 pF1KA1 LPSTSFSFQ ::::::::: NP_056 LPSTSFSFQ >>XP_006712049 (OMIM: 607386,615630,616394) PREDICTED: i (1728 aa) initn: 11444 init1: 11444 opt: 11444 Z-score: 12712.4 bits: 2365.3 E(85289): 0 Smith-Waterman score: 11444; 100.0% identity (100.0% similar) in 1728 aa overlap (22-1749:1-1728) 10 20 30 40 50 60 pF1KA1 MHLKHLRTLLSPQDGAAKVTCMAWSQNNAKFAVCTVDRVVLLYDEHGERRDKFSTKPADM ::::::::::::::::::::::::::::::::::::::: XP_006 MAWSQNNAKFAVCTVDRVVLLYDEHGERRDKFSTKPADM 10 20 30 70 80 90 100 110 120 pF1KA1 KYGRKSYMVKGMAFSPDSTKIAIGQTDNIIYVYKIGEDWGDKKVICNKFIQTSAVTCLQW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KYGRKSYMVKGMAFSPDSTKIAIGQTDNIIYVYKIGEDWGDKKVICNKFIQTSAVTCLQW 40 50 60 70 80 90 130 140 150 160 170 180 pF1KA1 PAEYIIVFGLAEGKVRLANTKTNKSSTIYGTESYVVSLTTNCSGKGILSGHADGTIVRYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PAEYIIVFGLAEGKVRLANTKTNKSSTIYGTESYVVSLTTNCSGKGILSGHADGTIVRYF 100 110 120 130 140 150 190 200 210 220 230 240 pF1KA1 FDDEGSGESQGKLVNHPCPPYALAWATNSIVAAGCDRKIVAYGKEGHMLQTFDYSRDPQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FDDEGSGESQGKLVNHPCPPYALAWATNSIVAAGCDRKIVAYGKEGHMLQTFDYSRDPQE 160 170 180 190 200 210 250 260 270 280 290 300 pF1KA1 REFTTAVSSPGGQSVVLGSYDRLRVFNWIPRRSIWEEAKPKEITNLYTITALAWKRDGSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 REFTTAVSSPGGQSVVLGSYDRLRVFNWIPRRSIWEEAKPKEITNLYTITALAWKRDGSR 220 230 240 250 260 270 310 320 330 340 350 360 pF1KA1 LCVGTLCGGVEQFDCCLRRSIYKNKFELTYVGPSQVIVKNLSSGTRVVLKSHYGYEVEEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LCVGTLCGGVEQFDCCLRRSIYKNKFELTYVGPSQVIVKNLSSGTRVVLKSHYGYEVEEV 280 290 300 310 320 330 370 380 390 400 410 420 pF1KA1 KILGKERYLVAHTSETLLLGDLNTNRLSEIAWQGSGGNEKYFFENENVCMIFNAGELTLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KILGKERYLVAHTSETLLLGDLNTNRLSEIAWQGSGGNEKYFFENENVCMIFNAGELTLV 340 350 360 370 380 390 430 440 450 460 470 480 pF1KA1 EYGNNDTLGSVRTEFMNPHLISVRINERCQRGTEDNKKLAYLIDIKTIAIVDLIGGYNIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EYGNNDTLGSVRTEFMNPHLISVRINERCQRGTEDNKKLAYLIDIKTIAIVDLIGGYNIG 400 410 420 430 440 450 490 500 510 520 530 540 pF1KA1 TVSHESRVDWLELNETGHKLLFRDRKLRLHLYDIESCSKTMILNFCSYMQWVPGSDVLVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TVSHESRVDWLELNETGHKLLFRDRKLRLHLYDIESCSKTMILNFCSYMQWVPGSDVLVA 460 470 480 490 500 510 550 560 570 580 590 600 pF1KA1 QNRNSLCVWYNIEAPERVTMFTIRGDVIGLERGGGKTEVMVMEGVTTVAYTLDEGLIEFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QNRNSLCVWYNIEAPERVTMFTIRGDVIGLERGGGKTEVMVMEGVTTVAYTLDEGLIEFG 520 530 540 550 560 570 610 620 630 640 650 660 pF1KA1 TAIDDGNYIRATAFLETLEMTPETEAMWKTLSKLALEARQLHIAERCFSALGQVAKARFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TAIDDGNYIRATAFLETLEMTPETEAMWKTLSKLALEARQLHIAERCFSALGQVAKARFL 580 590 600 610 620 630 670 680 690 700 710 720 pF1KA1 HETNEIADQVSREYGGEGTDFYQVRARLAMLEKNYKLAEMIFLEQNAVEEAMGMYQELHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HETNEIADQVSREYGGEGTDFYQVRARLAMLEKNYKLAEMIFLEQNAVEEAMGMYQELHR 640 650 660 670 680 690 730 740 750 760 770 780 pF1KA1 WDECIAVAEAKGHPALEKLRRSYYQWLMDTQQEERAGELQESQGDGLAAISLYLKAGLPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 WDECIAVAEAKGHPALEKLRRSYYQWLMDTQQEERAGELQESQGDGLAAISLYLKAGLPA 700 710 720 730 740 750 790 800 810 820 830 840 pF1KA1 KAARLVLTREELLANTELVEHITAALIKGELYERAGDLFEKIHNPQKALECYRKGNAFMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KAARLVLTREELLANTELVEHITAALIKGELYERAGDLFEKIHNPQKALECYRKGNAFMK 760 770 780 790 800 810 850 860 870 880 890 900 pF1KA1 AVELARLAFPVEVVKLEEAWGDHLVQQKQLDAAINHYIEARCSIKAIEAALGARQWKKAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AVELARLAFPVEVVKLEEAWGDHLVQQKQLDAAINHYIEARCSIKAIEAALGARQWKKAI 820 830 840 850 860 870 910 920 930 940 950 960 pF1KA1 YILDLQDRNTASKYYPLVAQHYASLQEYEIAEELYTKGDRTKDAIDMYTQAGRWEQAHKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YILDLQDRNTASKYYPLVAQHYASLQEYEIAEELYTKGDRTKDAIDMYTQAGRWEQAHKL 880 890 900 910 920 930 970 980 990 1000 1010 1020 pF1KA1 AMKCMRPEDVSVLYITQAQEMEKQGKYREAERLYVTVQEPDLAITMYKKHKLYDDMIRLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AMKCMRPEDVSVLYITQAQEMEKQGKYREAERLYVTVQEPDLAITMYKKHKLYDDMIRLV 940 950 960 970 980 990 1030 1040 1050 1060 1070 1080 pF1KA1 GKHHPDLLSDTHLHLGKELEAEGRLQEAEYHYLEAQEWKATVNMYRASGLWEEAYRVART :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GKHHPDLLSDTHLHLGKELEAEGRLQEAEYHYLEAQEWKATVNMYRASGLWEEAYRVART 1000 1010 1020 1030 1040 1050 1090 1100 1110 1120 1130 1140 pF1KA1 QGGANAHKHVAYLWAKSLGGEAAVRLLNKLGLLEAAVDHAADNCSFEFAFELSRLALKHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QGGANAHKHVAYLWAKSLGGEAAVRLLNKLGLLEAAVDHAADNCSFEFAFELSRLALKHK 1060 1070 1080 1090 1100 1110 1150 1160 1170 1180 1190 1200 pF1KA1 TPEVHLKYAMFLEDEGKFEEAEAEFIRAGKPKEAVLMFVHNQDWEAAQRVAEAHDPDSVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TPEVHLKYAMFLEDEGKFEEAEAEFIRAGKPKEAVLMFVHNQDWEAAQRVAEAHDPDSVA 1120 1130 1140 1150 1160 1170 1210 1220 1230 1240 1250 1260 pF1KA1 EVLVGQARGALEEKDFQKAEGLLLRAQRPGLALNYYKEAGLWSDALRICKDYVPSQLEAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EVLVGQARGALEEKDFQKAEGLLLRAQRPGLALNYYKEAGLWSDALRICKDYVPSQLEAL 1180 1190 1200 1210 1220 1230 1270 1280 1290 1300 1310 1320 pF1KA1 QEEYEREATKKGARGVEGFVEQARHWEQAGEYSRAVDCYLKVRDSGNSGLAEKCWMKAAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QEEYEREATKKGARGVEGFVEQARHWEQAGEYSRAVDCYLKVRDSGNSGLAEKCWMKAAE 1240 1250 1260 1270 1280 1290 1330 1340 1350 1360 1370 1380 pF1KA1 LSIKFLPPQRNMEVVLAVGPQLIGIGKHSAAAELYLNLDLVKEAIDAFIEGEEWNKAKRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LSIKFLPPQRNMEVVLAVGPQLIGIGKHSAAAELYLNLDLVKEAIDAFIEGEEWNKAKRV 1300 1310 1320 1330 1340 1350 1390 1400 1410 1420 1430 1440 pF1KA1 AKELDPRYEDYVDQHYKEFLKNQGKVDSLVGVDVIAALDLYVEQGQWDKCIETATKQNYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AKELDPRYEDYVDQHYKEFLKNQGKVDSLVGVDVIAALDLYVEQGQWDKCIETATKQNYK 1360 1370 1380 1390 1400 1410 1450 1460 1470 1480 1490 1500 pF1KA1 ILHKYVALYATHLIREGSSAQALALYVQHGAPANPQNFNIYKRIFTDMVSSPGTNCAEAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ILHKYVALYATHLIREGSSAQALALYVQHGAPANPQNFNIYKRIFTDMVSSPGTNCAEAY 1420 1430 1440 1450 1460 1470 1510 1520 1530 1540 1550 1560 pF1KA1 HSWADLRDVLFNLCENLVKSSEANSPAHEEFKTMLLIAHYYATRSAAQSVKQLETVAARL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HSWADLRDVLFNLCENLVKSSEANSPAHEEFKTMLLIAHYYATRSAAQSVKQLETVAARL 1480 1490 1500 1510 1520 1530 1570 1580 1590 1600 1610 1620 pF1KA1 SVSLLRHTQLLPVDKAFYEAGIAAKAVGWDNMAFIFLNRFLDLTDAIEEGTLDGLDHSDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SVSLLRHTQLLPVDKAFYEAGIAAKAVGWDNMAFIFLNRFLDLTDAIEEGTLDGLDHSDF 1540 1550 1560 1570 1580 1590 1630 1640 1650 1660 1670 1680 pF1KA1 QDTDIPFEVPLPAKQHVPEAEREEVRDWVLTVSMDQRLEQVLPRDERGAYEASLVAASTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QDTDIPFEVPLPAKQHVPEAEREEVRDWVLTVSMDQRLEQVLPRDERGAYEASLVAASTG 1600 1610 1620 1630 1640 1650 1690 1700 1710 1720 1730 1740 pF1KA1 VRALPCLITGYPILRNKIEFKRPGKAANKDNWNKFLMAIKTSHSPVCQDVLKFISQWCGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VRALPCLITGYPILRNKIEFKRPGKAANKDNWNKFLMAIKTSHSPVCQDVLKFISQWCGG 1660 1670 1680 1690 1700 1710 pF1KA1 LPSTSFSFQ ::::::::: XP_006 LPSTSFSFQ 1720 >>XP_006712050 (OMIM: 607386,615630,616394) PREDICTED: i (1716 aa) initn: 10837 init1: 10609 opt: 10609 Z-score: 11784.3 bits: 2193.6 E(85289): 0 Smith-Waterman score: 11280; 98.1% identity (98.1% similar) in 1749 aa overlap (1-1749:1-1716) 10 20 30 40 50 60 pF1KA1 MHLKHLRTLLSPQDGAAKVTCMAWSQNNAKFAVCTVDRVVLLYDEHGERRDKFSTKPADM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MHLKHLRTLLSPQDGAAKVTCMAWSQNNAKFAVCTVDRVVLLYDEHGERRDKFSTKPADM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 KYGRKSYMVKGMAFSPDSTKIAIGQTDNIIYVYKIGEDWGDKKVICNKFIQTSAVTCLQW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KYGRKSYMVKGMAFSPDSTKIAIGQTDNIIYVYKIGEDWGDKKVICNKFIQTSAVTCLQW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 PAEYIIVFGLAEGKVRLANTKTNKSSTIYGTESYVVSLTTNCSGKGILSGHADGTIVRYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PAEYIIVFGLAEGKVRLANTKTNKSSTIYGTESYVVSLTTNCSGKGILSGHADGTIVRYF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 FDDEGSGESQGKLVNHPCPPYALAWATNSIVAAGCDRKIVAYGKEGHMLQTFDYSRDPQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FDDEGSGESQGKLVNHPCPPYALAWATNSIVAAGCDRKIVAYGKEGHMLQTFDYSRDPQE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 REFTTAVSSPGGQSVVLGSYDRLRVFNWIPRRSIWEEAKPKEITNLYTITALAWKRDGSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 REFTTAVSSPGGQSVVLGSYDRLRVFNWIPRRSIWEEAKPKEITNLYTITALAWKRDGSR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 LCVGTLCGGVEQFDCCLRRSIYKNKFELTYVGPSQVIVKNLSSGTRVVLKSHYGYEVEEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LCVGTLCGGVEQFDCCLRRSIYKNKFELTYVGPSQVIVKNLSSGTRVVLKSHYGYEVEEV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 KILGKERYLVAHTSETLLLGDLNTNRLSEIAWQGSGGNEKYFFENENVCMIFNAGELTLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KILGKERYLVAHTSETLLLGDLNTNRLSEIAWQGSGGNEKYFFENENVCMIFNAGELTLV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 EYGNNDTLGSVRTEFMNPHLISVRINERCQRGTEDNKKLAYLIDIKTIAIVDLIGGYNIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EYGNNDTLGSVRTEFMNPHLISVRINERCQRGTEDNKKLAYLIDIKTIAIVDLIGGYNIG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 TVSHESRVDWLELNETGHKLLFRDRKLRLHLYDIESCSKTMILNFCSYMQWVPGSDVLVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TVSHESRVDWLELNETGHKLLFRDRKLRLHLYDIESCSKTMILNFCSYMQWVPGSDVLVA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 QNRNSLCVWYNIEAPERVTMFTIRGDVIGLERGGGKTEVMVMEGVTTVAYTLDEGLIEFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QNRNSLCVWYNIEAPERVTMFTIRGDVIGLERGGGKTEVMVMEGVTTVAYTLDEGLIEFG 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 TAIDDGNYIRATAFLETLEMTPETEAMWKTLSKLALEARQLHIAERCFSALGQVAKARFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TAIDDGNYIRATAFLETLEMTPETEAMWKTLSKLALEARQLHIAERCFSALGQVAKARFL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 HETNEIADQVSREYGGEGTDFYQVRARLAMLEKNYKLAEMIFLEQNAVEEAMGMYQELHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HETNEIADQVSREYGGEGTDFYQVRARLAMLEKNYKLAEMIFLEQNAVEEAMGMYQELHR 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 WDECIAVAEAKGHPALEKLRRSYYQWLMDTQQEERAGELQESQGDGLAAISLYLKAGLPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 WDECIAVAEAKGHPALEKLRRSYYQWLMDTQQEERAGELQESQGDGLAAISLYLKAGLPA 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 KAARLVLTREELLANTELVEHITAALIKGELYERAGDLFEKIHNPQKALECYRKGNAFMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KAARLVLTREELLANTELVEHITAALIKGELYERAGDLFEKIHNPQKALECYRKGNAFMK 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 AVELARLAFPVEVVKLEEAWGDHLVQQKQLDAAINHYIEARCSIKAIEAALGARQWKKAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AVELARLAFPVEVVKLEEAWGDHLVQQKQLDAAINHYIEARCSIKAIEAALGARQWKKAI 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 YILDLQDRNTASKYYPLVAQHYASLQEYEIAEELYTKGDRTKDAIDMYTQAGRWEQAHKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YILDLQDRNTASKYYPLVAQHYASLQEYEIAEELYTKGDRTKDAIDMYTQAGRWEQAHKL 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 AMKCMRPEDVSVLYITQAQEMEKQGKYREAERLYVTVQEPDLAITMYKKHKLYDDMIRLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AMKCMRPEDVSVLYITQAQEMEKQGKYREAERLYVTVQEPDLAITMYKKHKLYDDMIRLV 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA1 GKHHPDLLSDTHLHLGKELEAEGRLQEAEYHYLEAQEWKATVNMYRASGLWEEAYRVART :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GKHHPDLLSDTHLHLGKELEAEGRLQEAEYHYLEAQEWKATVNMYRASGLWEEAYRVART 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA1 QGGANAHKHVAYLWAKSLGGEAAVRLLNKLGLLEAAVDHAADNCSFEFAFELSRLALKHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QGGANAHKHVAYLWAKSLGGEAAVRLLNKLGLLEAAVDHAADNCSFEFAFELSRLALKHK 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA1 TPEVHLKYAMFLEDEGKFEEAEAEFIRAGKPKEAVLMFVHNQDWEAAQRVAEAHDPDSVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TPEVHLKYAMFLEDEGKFEEAEAEFIRAGKPKEAVLMFVHNQDWEAAQRVAEAHDPDSVA 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA1 EVLVGQARGALEEKDFQKAEGLLLRAQRPGLALNYYKEAGLWSDALRICKDYVPSQLEAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EVLVGQARGALEEKDFQKAEGLLLRAQRPGLALNYYKEAGLWSDALRICKDYVPSQLEAL 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA1 QEEYEREATKKGARGVEGFVEQARHWEQAGEYSRAVDCYLKVRDSGNSGLAEKCWMKAAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QEEYEREATKKGARGVEGFVEQARHWEQAGEYSRAVDCYLKVRDSGNSGLAEKCWMKAAE 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA1 LSIKFLPPQRNMEVVLAVGPQLIGIGKHSAAAELYLNLDLVKEAIDAFIEGEEWNKAKRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LSIKFLPPQRNMEVVLAVGPQLIGIGKHSAAAELYLNLDLVKEAIDAFIEGEEWNKAKRV 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA1 AKELDPRYEDYVDQHYKEFLKNQGKVDSLVGVDVIAALDLYVEQGQWDKCIETATKQNYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AKELDPRYEDYVDQHYKEFLKNQGKVDSLVGVDVIAALDLYVEQGQWDKCIETATKQNYK 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA1 ILHKYVALYATHLIREGSSAQALALYVQHGAPANPQNFNIYKRIFTDMVSSPGTNCAEAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ILHKYVALYATHLIREGSSAQALALYVQHGAPANPQNFNIYKRIFTDMVSSPGTNCAEAY 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA1 HSWADLRDVLFNLCENLVKSSEANSPAHEEFKTMLLIAHYYATRSAAQSVKQLETVAARL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HSWADLRDVLFNLCENLVKSSEANSPAHEEFKTMLLIAHYYATRSAAQSVKQLETVAARL 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA1 SVSLLRHTQLLPVDKAFYEAGIAAKAVGWDNMAFIFLNRFLDLTDAIEEGTLDGLDHSDF ::::::::::::::::::::::::::::::::::::::::::::: XP_006 SVSLLRHTQLLPVDKAFYEAGIAAKAVGWDNMAFIFLNRFLDLTD--------------- 1570 1580 1590 1600 1630 1640 1650 1660 1670 1680 pF1KA1 QDTDIPFEVPLPAKQHVPEAEREEVRDWVLTVSMDQRLEQVLPRDERGAYEASLVAASTG :::::::::::::::::::::::::::::::::::::::::: XP_006 ------------------EAEREEVRDWVLTVSMDQRLEQVLPRDERGAYEASLVAASTG 1610 1620 1630 1640 1690 1700 1710 1720 1730 1740 pF1KA1 VRALPCLITGYPILRNKIEFKRPGKAANKDNWNKFLMAIKTSHSPVCQDVLKFISQWCGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VRALPCLITGYPILRNKIEFKRPGKAANKDNWNKFLMAIKTSHSPVCQDVLKFISQWCGG 1650 1660 1670 1680 1690 1700 pF1KA1 LPSTSFSFQ ::::::::: XP_006 LPSTSFSFQ 1710 >>XP_016859280 (OMIM: 607386,615630,616394) PREDICTED: i (1522 aa) initn: 10052 init1: 10052 opt: 10052 Z-score: 11165.8 bits: 2079.0 E(85289): 0 Smith-Waterman score: 10052; 100.0% identity (100.0% similar) in 1522 aa overlap (228-1749:1-1522) 200 210 220 230 240 250 pF1KA1 CPPYALAWATNSIVAAGCDRKIVAYGKEGHMLQTFDYSRDPQEREFTTAVSSPGGQSVVL :::::::::::::::::::::::::::::: XP_016 MLQTFDYSRDPQEREFTTAVSSPGGQSVVL 10 20 30 260 270 280 290 300 310 pF1KA1 GSYDRLRVFNWIPRRSIWEEAKPKEITNLYTITALAWKRDGSRLCVGTLCGGVEQFDCCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSYDRLRVFNWIPRRSIWEEAKPKEITNLYTITALAWKRDGSRLCVGTLCGGVEQFDCCL 40 50 60 70 80 90 320 330 340 350 360 370 pF1KA1 RRSIYKNKFELTYVGPSQVIVKNLSSGTRVVLKSHYGYEVEEVKILGKERYLVAHTSETL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRSIYKNKFELTYVGPSQVIVKNLSSGTRVVLKSHYGYEVEEVKILGKERYLVAHTSETL 100 110 120 130 140 150 380 390 400 410 420 430 pF1KA1 LLGDLNTNRLSEIAWQGSGGNEKYFFENENVCMIFNAGELTLVEYGNNDTLGSVRTEFMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLGDLNTNRLSEIAWQGSGGNEKYFFENENVCMIFNAGELTLVEYGNNDTLGSVRTEFMN 160 170 180 190 200 210 440 450 460 470 480 490 pF1KA1 PHLISVRINERCQRGTEDNKKLAYLIDIKTIAIVDLIGGYNIGTVSHESRVDWLELNETG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PHLISVRINERCQRGTEDNKKLAYLIDIKTIAIVDLIGGYNIGTVSHESRVDWLELNETG 220 230 240 250 260 270 500 510 520 530 540 550 pF1KA1 HKLLFRDRKLRLHLYDIESCSKTMILNFCSYMQWVPGSDVLVAQNRNSLCVWYNIEAPER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HKLLFRDRKLRLHLYDIESCSKTMILNFCSYMQWVPGSDVLVAQNRNSLCVWYNIEAPER 280 290 300 310 320 330 560 570 580 590 600 610 pF1KA1 VTMFTIRGDVIGLERGGGKTEVMVMEGVTTVAYTLDEGLIEFGTAIDDGNYIRATAFLET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VTMFTIRGDVIGLERGGGKTEVMVMEGVTTVAYTLDEGLIEFGTAIDDGNYIRATAFLET 340 350 360 370 380 390 620 630 640 650 660 670 pF1KA1 LEMTPETEAMWKTLSKLALEARQLHIAERCFSALGQVAKARFLHETNEIADQVSREYGGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LEMTPETEAMWKTLSKLALEARQLHIAERCFSALGQVAKARFLHETNEIADQVSREYGGE 400 410 420 430 440 450 680 690 700 710 720 730 pF1KA1 GTDFYQVRARLAMLEKNYKLAEMIFLEQNAVEEAMGMYQELHRWDECIAVAEAKGHPALE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GTDFYQVRARLAMLEKNYKLAEMIFLEQNAVEEAMGMYQELHRWDECIAVAEAKGHPALE 460 470 480 490 500 510 740 750 760 770 780 790 pF1KA1 KLRRSYYQWLMDTQQEERAGELQESQGDGLAAISLYLKAGLPAKAARLVLTREELLANTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLRRSYYQWLMDTQQEERAGELQESQGDGLAAISLYLKAGLPAKAARLVLTREELLANTE 520 530 540 550 560 570 800 810 820 830 840 850 pF1KA1 LVEHITAALIKGELYERAGDLFEKIHNPQKALECYRKGNAFMKAVELARLAFPVEVVKLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LVEHITAALIKGELYERAGDLFEKIHNPQKALECYRKGNAFMKAVELARLAFPVEVVKLE 580 590 600 610 620 630 860 870 880 890 900 910 pF1KA1 EAWGDHLVQQKQLDAAINHYIEARCSIKAIEAALGARQWKKAIYILDLQDRNTASKYYPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EAWGDHLVQQKQLDAAINHYIEARCSIKAIEAALGARQWKKAIYILDLQDRNTASKYYPL 640 650 660 670 680 690 920 930 940 950 960 970 pF1KA1 VAQHYASLQEYEIAEELYTKGDRTKDAIDMYTQAGRWEQAHKLAMKCMRPEDVSVLYITQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VAQHYASLQEYEIAEELYTKGDRTKDAIDMYTQAGRWEQAHKLAMKCMRPEDVSVLYITQ 700 710 720 730 740 750 980 990 1000 1010 1020 1030 pF1KA1 AQEMEKQGKYREAERLYVTVQEPDLAITMYKKHKLYDDMIRLVGKHHPDLLSDTHLHLGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AQEMEKQGKYREAERLYVTVQEPDLAITMYKKHKLYDDMIRLVGKHHPDLLSDTHLHLGK 760 770 780 790 800 810 1040 1050 1060 1070 1080 1090 pF1KA1 ELEAEGRLQEAEYHYLEAQEWKATVNMYRASGLWEEAYRVARTQGGANAHKHVAYLWAKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELEAEGRLQEAEYHYLEAQEWKATVNMYRASGLWEEAYRVARTQGGANAHKHVAYLWAKS 820 830 840 850 860 870 1100 1110 1120 1130 1140 1150 pF1KA1 LGGEAAVRLLNKLGLLEAAVDHAADNCSFEFAFELSRLALKHKTPEVHLKYAMFLEDEGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGGEAAVRLLNKLGLLEAAVDHAADNCSFEFAFELSRLALKHKTPEVHLKYAMFLEDEGK 880 890 900 910 920 930 1160 1170 1180 1190 1200 1210 pF1KA1 FEEAEAEFIRAGKPKEAVLMFVHNQDWEAAQRVAEAHDPDSVAEVLVGQARGALEEKDFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FEEAEAEFIRAGKPKEAVLMFVHNQDWEAAQRVAEAHDPDSVAEVLVGQARGALEEKDFQ 940 950 960 970 980 990 1220 1230 1240 1250 1260 1270 pF1KA1 KAEGLLLRAQRPGLALNYYKEAGLWSDALRICKDYVPSQLEALQEEYEREATKKGARGVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KAEGLLLRAQRPGLALNYYKEAGLWSDALRICKDYVPSQLEALQEEYEREATKKGARGVE 1000 1010 1020 1030 1040 1050 1280 1290 1300 1310 1320 1330 pF1KA1 GFVEQARHWEQAGEYSRAVDCYLKVRDSGNSGLAEKCWMKAAELSIKFLPPQRNMEVVLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GFVEQARHWEQAGEYSRAVDCYLKVRDSGNSGLAEKCWMKAAELSIKFLPPQRNMEVVLA 1060 1070 1080 1090 1100 1110 1340 1350 1360 1370 1380 1390 pF1KA1 VGPQLIGIGKHSAAAELYLNLDLVKEAIDAFIEGEEWNKAKRVAKELDPRYEDYVDQHYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VGPQLIGIGKHSAAAELYLNLDLVKEAIDAFIEGEEWNKAKRVAKELDPRYEDYVDQHYK 1120 1130 1140 1150 1160 1170 1400 1410 1420 1430 1440 1450 pF1KA1 EFLKNQGKVDSLVGVDVIAALDLYVEQGQWDKCIETATKQNYKILHKYVALYATHLIREG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EFLKNQGKVDSLVGVDVIAALDLYVEQGQWDKCIETATKQNYKILHKYVALYATHLIREG 1180 1190 1200 1210 1220 1230 1460 1470 1480 1490 1500 1510 pF1KA1 SSAQALALYVQHGAPANPQNFNIYKRIFTDMVSSPGTNCAEAYHSWADLRDVLFNLCENL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSAQALALYVQHGAPANPQNFNIYKRIFTDMVSSPGTNCAEAYHSWADLRDVLFNLCENL 1240 1250 1260 1270 1280 1290 1520 1530 1540 1550 1560 1570 pF1KA1 VKSSEANSPAHEEFKTMLLIAHYYATRSAAQSVKQLETVAARLSVSLLRHTQLLPVDKAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VKSSEANSPAHEEFKTMLLIAHYYATRSAAQSVKQLETVAARLSVSLLRHTQLLPVDKAF 1300 1310 1320 1330 1340 1350 1580 1590 1600 1610 1620 1630 pF1KA1 YEAGIAAKAVGWDNMAFIFLNRFLDLTDAIEEGTLDGLDHSDFQDTDIPFEVPLPAKQHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YEAGIAAKAVGWDNMAFIFLNRFLDLTDAIEEGTLDGLDHSDFQDTDIPFEVPLPAKQHV 1360 1370 1380 1390 1400 1410 1640 1650 1660 1670 1680 1690 pF1KA1 PEAEREEVRDWVLTVSMDQRLEQVLPRDERGAYEASLVAASTGVRALPCLITGYPILRNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PEAEREEVRDWVLTVSMDQRLEQVLPRDERGAYEASLVAASTGVRALPCLITGYPILRNK 1420 1430 1440 1450 1460 1470 1700 1710 1720 1730 1740 pF1KA1 IEFKRPGKAANKDNWNKFLMAIKTSHSPVCQDVLKFISQWCGGLPSTSFSFQ :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IEFKRPGKAANKDNWNKFLMAIKTSHSPVCQDVLKFISQWCGGLPSTSFSFQ 1480 1490 1500 1510 1520 >>XP_011531059 (OMIM: 607386,615630,616394) PREDICTED: i (1522 aa) initn: 10052 init1: 10052 opt: 10052 Z-score: 11165.8 bits: 2079.0 E(85289): 0 Smith-Waterman score: 10052; 100.0% identity (100.0% similar) in 1522 aa overlap (228-1749:1-1522) 200 210 220 230 240 250 pF1KA1 CPPYALAWATNSIVAAGCDRKIVAYGKEGHMLQTFDYSRDPQEREFTTAVSSPGGQSVVL :::::::::::::::::::::::::::::: XP_011 MLQTFDYSRDPQEREFTTAVSSPGGQSVVL 10 20 30 260 270 280 290 300 310 pF1KA1 GSYDRLRVFNWIPRRSIWEEAKPKEITNLYTITALAWKRDGSRLCVGTLCGGVEQFDCCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSYDRLRVFNWIPRRSIWEEAKPKEITNLYTITALAWKRDGSRLCVGTLCGGVEQFDCCL 40 50 60 70 80 90 320 330 340 350 360 370 pF1KA1 RRSIYKNKFELTYVGPSQVIVKNLSSGTRVVLKSHYGYEVEEVKILGKERYLVAHTSETL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RRSIYKNKFELTYVGPSQVIVKNLSSGTRVVLKSHYGYEVEEVKILGKERYLVAHTSETL 100 110 120 130 140 150 380 390 400 410 420 430 pF1KA1 LLGDLNTNRLSEIAWQGSGGNEKYFFENENVCMIFNAGELTLVEYGNNDTLGSVRTEFMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLGDLNTNRLSEIAWQGSGGNEKYFFENENVCMIFNAGELTLVEYGNNDTLGSVRTEFMN 160 170 180 190 200 210 440 450 460 470 480 490 pF1KA1 PHLISVRINERCQRGTEDNKKLAYLIDIKTIAIVDLIGGYNIGTVSHESRVDWLELNETG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PHLISVRINERCQRGTEDNKKLAYLIDIKTIAIVDLIGGYNIGTVSHESRVDWLELNETG 220 230 240 250 260 270 500 510 520 530 540 550 pF1KA1 HKLLFRDRKLRLHLYDIESCSKTMILNFCSYMQWVPGSDVLVAQNRNSLCVWYNIEAPER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HKLLFRDRKLRLHLYDIESCSKTMILNFCSYMQWVPGSDVLVAQNRNSLCVWYNIEAPER 280 290 300 310 320 330 560 570 580 590 600 610 pF1KA1 VTMFTIRGDVIGLERGGGKTEVMVMEGVTTVAYTLDEGLIEFGTAIDDGNYIRATAFLET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VTMFTIRGDVIGLERGGGKTEVMVMEGVTTVAYTLDEGLIEFGTAIDDGNYIRATAFLET 340 350 360 370 380 390 620 630 640 650 660 670 pF1KA1 LEMTPETEAMWKTLSKLALEARQLHIAERCFSALGQVAKARFLHETNEIADQVSREYGGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LEMTPETEAMWKTLSKLALEARQLHIAERCFSALGQVAKARFLHETNEIADQVSREYGGE 400 410 420 430 440 450 680 690 700 710 720 730 pF1KA1 GTDFYQVRARLAMLEKNYKLAEMIFLEQNAVEEAMGMYQELHRWDECIAVAEAKGHPALE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GTDFYQVRARLAMLEKNYKLAEMIFLEQNAVEEAMGMYQELHRWDECIAVAEAKGHPALE 460 470 480 490 500 510 740 750 760 770 780 790 pF1KA1 KLRRSYYQWLMDTQQEERAGELQESQGDGLAAISLYLKAGLPAKAARLVLTREELLANTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLRRSYYQWLMDTQQEERAGELQESQGDGLAAISLYLKAGLPAKAARLVLTREELLANTE 520 530 540 550 560 570 800 810 820 830 840 850 pF1KA1 LVEHITAALIKGELYERAGDLFEKIHNPQKALECYRKGNAFMKAVELARLAFPVEVVKLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LVEHITAALIKGELYERAGDLFEKIHNPQKALECYRKGNAFMKAVELARLAFPVEVVKLE 580 590 600 610 620 630 860 870 880 890 900 910 pF1KA1 EAWGDHLVQQKQLDAAINHYIEARCSIKAIEAALGARQWKKAIYILDLQDRNTASKYYPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EAWGDHLVQQKQLDAAINHYIEARCSIKAIEAALGARQWKKAIYILDLQDRNTASKYYPL 640 650 660 670 680 690 920 930 940 950 960 970 pF1KA1 VAQHYASLQEYEIAEELYTKGDRTKDAIDMYTQAGRWEQAHKLAMKCMRPEDVSVLYITQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VAQHYASLQEYEIAEELYTKGDRTKDAIDMYTQAGRWEQAHKLAMKCMRPEDVSVLYITQ 700 710 720 730 740 750 980 990 1000 1010 1020 1030 pF1KA1 AQEMEKQGKYREAERLYVTVQEPDLAITMYKKHKLYDDMIRLVGKHHPDLLSDTHLHLGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AQEMEKQGKYREAERLYVTVQEPDLAITMYKKHKLYDDMIRLVGKHHPDLLSDTHLHLGK 760 770 780 790 800 810 1040 1050 1060 1070 1080 1090 pF1KA1 ELEAEGRLQEAEYHYLEAQEWKATVNMYRASGLWEEAYRVARTQGGANAHKHVAYLWAKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELEAEGRLQEAEYHYLEAQEWKATVNMYRASGLWEEAYRVARTQGGANAHKHVAYLWAKS 820 830 840 850 860 870 1100 1110 1120 1130 1140 1150 pF1KA1 LGGEAAVRLLNKLGLLEAAVDHAADNCSFEFAFELSRLALKHKTPEVHLKYAMFLEDEGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LGGEAAVRLLNKLGLLEAAVDHAADNCSFEFAFELSRLALKHKTPEVHLKYAMFLEDEGK 880 890 900 910 920 930 1160 1170 1180 1190 1200 1210 pF1KA1 FEEAEAEFIRAGKPKEAVLMFVHNQDWEAAQRVAEAHDPDSVAEVLVGQARGALEEKDFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FEEAEAEFIRAGKPKEAVLMFVHNQDWEAAQRVAEAHDPDSVAEVLVGQARGALEEKDFQ 940 950 960 970 980 990 1220 1230 1240 1250 1260 1270 pF1KA1 KAEGLLLRAQRPGLALNYYKEAGLWSDALRICKDYVPSQLEALQEEYEREATKKGARGVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KAEGLLLRAQRPGLALNYYKEAGLWSDALRICKDYVPSQLEALQEEYEREATKKGARGVE 1000 1010 1020 1030 1040 1050 1280 1290 1300 1310 1320 1330 pF1KA1 GFVEQARHWEQAGEYSRAVDCYLKVRDSGNSGLAEKCWMKAAELSIKFLPPQRNMEVVLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GFVEQARHWEQAGEYSRAVDCYLKVRDSGNSGLAEKCWMKAAELSIKFLPPQRNMEVVLA 1060 1070 1080 1090 1100 1110 1340 1350 1360 1370 1380 1390 pF1KA1 VGPQLIGIGKHSAAAELYLNLDLVKEAIDAFIEGEEWNKAKRVAKELDPRYEDYVDQHYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VGPQLIGIGKHSAAAELYLNLDLVKEAIDAFIEGEEWNKAKRVAKELDPRYEDYVDQHYK 1120 1130 1140 1150 1160 1170 1400 1410 1420 1430 1440 1450 pF1KA1 EFLKNQGKVDSLVGVDVIAALDLYVEQGQWDKCIETATKQNYKILHKYVALYATHLIREG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EFLKNQGKVDSLVGVDVIAALDLYVEQGQWDKCIETATKQNYKILHKYVALYATHLIREG 1180 1190 1200 1210 1220 1230 1460 1470 1480 1490 1500 1510 pF1KA1 SSAQALALYVQHGAPANPQNFNIYKRIFTDMVSSPGTNCAEAYHSWADLRDVLFNLCENL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSAQALALYVQHGAPANPQNFNIYKRIFTDMVSSPGTNCAEAYHSWADLRDVLFNLCENL 1240 1250 1260 1270 1280 1290 1520 1530 1540 1550 1560 1570 pF1KA1 VKSSEANSPAHEEFKTMLLIAHYYATRSAAQSVKQLETVAARLSVSLLRHTQLLPVDKAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VKSSEANSPAHEEFKTMLLIAHYYATRSAAQSVKQLETVAARLSVSLLRHTQLLPVDKAF 1300 1310 1320 1330 1340 1350 1580 1590 1600 1610 1620 1630 pF1KA1 YEAGIAAKAVGWDNMAFIFLNRFLDLTDAIEEGTLDGLDHSDFQDTDIPFEVPLPAKQHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YEAGIAAKAVGWDNMAFIFLNRFLDLTDAIEEGTLDGLDHSDFQDTDIPFEVPLPAKQHV 1360 1370 1380 1390 1400 1410 1640 1650 1660 1670 1680 1690 pF1KA1 PEAEREEVRDWVLTVSMDQRLEQVLPRDERGAYEASLVAASTGVRALPCLITGYPILRNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PEAEREEVRDWVLTVSMDQRLEQVLPRDERGAYEASLVAASTGVRALPCLITGYPILRNK 1420 1430 1440 1450 1460 1470 1700 1710 1720 1730 1740 pF1KA1 IEFKRPGKAANKDNWNKFLMAIKTSHSPVCQDVLKFISQWCGGLPSTSFSFQ :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IEFKRPGKAANKDNWNKFLMAIKTSHSPVCQDVLKFISQWCGGLPSTSFSFQ 1480 1490 1500 1510 1520 >>XP_011531060 (OMIM: 607386,615630,616394) PREDICTED: i (1327 aa) initn: 9016 init1: 8736 opt: 8736 Z-score: 9703.8 bits: 1808.3 E(85289): 0 Smith-Waterman score: 8736; 99.9% identity (100.0% similar) in 1319 aa overlap (1-1319:1-1319) 10 20 30 40 50 60 pF1KA1 MHLKHLRTLLSPQDGAAKVTCMAWSQNNAKFAVCTVDRVVLLYDEHGERRDKFSTKPADM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MHLKHLRTLLSPQDGAAKVTCMAWSQNNAKFAVCTVDRVVLLYDEHGERRDKFSTKPADM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 KYGRKSYMVKGMAFSPDSTKIAIGQTDNIIYVYKIGEDWGDKKVICNKFIQTSAVTCLQW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KYGRKSYMVKGMAFSPDSTKIAIGQTDNIIYVYKIGEDWGDKKVICNKFIQTSAVTCLQW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 PAEYIIVFGLAEGKVRLANTKTNKSSTIYGTESYVVSLTTNCSGKGILSGHADGTIVRYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PAEYIIVFGLAEGKVRLANTKTNKSSTIYGTESYVVSLTTNCSGKGILSGHADGTIVRYF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 FDDEGSGESQGKLVNHPCPPYALAWATNSIVAAGCDRKIVAYGKEGHMLQTFDYSRDPQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FDDEGSGESQGKLVNHPCPPYALAWATNSIVAAGCDRKIVAYGKEGHMLQTFDYSRDPQE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 REFTTAVSSPGGQSVVLGSYDRLRVFNWIPRRSIWEEAKPKEITNLYTITALAWKRDGSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 REFTTAVSSPGGQSVVLGSYDRLRVFNWIPRRSIWEEAKPKEITNLYTITALAWKRDGSR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 LCVGTLCGGVEQFDCCLRRSIYKNKFELTYVGPSQVIVKNLSSGTRVVLKSHYGYEVEEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LCVGTLCGGVEQFDCCLRRSIYKNKFELTYVGPSQVIVKNLSSGTRVVLKSHYGYEVEEV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 KILGKERYLVAHTSETLLLGDLNTNRLSEIAWQGSGGNEKYFFENENVCMIFNAGELTLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KILGKERYLVAHTSETLLLGDLNTNRLSEIAWQGSGGNEKYFFENENVCMIFNAGELTLV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 EYGNNDTLGSVRTEFMNPHLISVRINERCQRGTEDNKKLAYLIDIKTIAIVDLIGGYNIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EYGNNDTLGSVRTEFMNPHLISVRINERCQRGTEDNKKLAYLIDIKTIAIVDLIGGYNIG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 TVSHESRVDWLELNETGHKLLFRDRKLRLHLYDIESCSKTMILNFCSYMQWVPGSDVLVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TVSHESRVDWLELNETGHKLLFRDRKLRLHLYDIESCSKTMILNFCSYMQWVPGSDVLVA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 QNRNSLCVWYNIEAPERVTMFTIRGDVIGLERGGGKTEVMVMEGVTTVAYTLDEGLIEFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QNRNSLCVWYNIEAPERVTMFTIRGDVIGLERGGGKTEVMVMEGVTTVAYTLDEGLIEFG 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 TAIDDGNYIRATAFLETLEMTPETEAMWKTLSKLALEARQLHIAERCFSALGQVAKARFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TAIDDGNYIRATAFLETLEMTPETEAMWKTLSKLALEARQLHIAERCFSALGQVAKARFL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 HETNEIADQVSREYGGEGTDFYQVRARLAMLEKNYKLAEMIFLEQNAVEEAMGMYQELHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HETNEIADQVSREYGGEGTDFYQVRARLAMLEKNYKLAEMIFLEQNAVEEAMGMYQELHR 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 WDECIAVAEAKGHPALEKLRRSYYQWLMDTQQEERAGELQESQGDGLAAISLYLKAGLPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WDECIAVAEAKGHPALEKLRRSYYQWLMDTQQEERAGELQESQGDGLAAISLYLKAGLPA 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 KAARLVLTREELLANTELVEHITAALIKGELYERAGDLFEKIHNPQKALECYRKGNAFMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KAARLVLTREELLANTELVEHITAALIKGELYERAGDLFEKIHNPQKALECYRKGNAFMK 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 AVELARLAFPVEVVKLEEAWGDHLVQQKQLDAAINHYIEARCSIKAIEAALGARQWKKAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AVELARLAFPVEVVKLEEAWGDHLVQQKQLDAAINHYIEARCSIKAIEAALGARQWKKAI 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 YILDLQDRNTASKYYPLVAQHYASLQEYEIAEELYTKGDRTKDAIDMYTQAGRWEQAHKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YILDLQDRNTASKYYPLVAQHYASLQEYEIAEELYTKGDRTKDAIDMYTQAGRWEQAHKL 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 AMKCMRPEDVSVLYITQAQEMEKQGKYREAERLYVTVQEPDLAITMYKKHKLYDDMIRLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AMKCMRPEDVSVLYITQAQEMEKQGKYREAERLYVTVQEPDLAITMYKKHKLYDDMIRLV 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA1 GKHHPDLLSDTHLHLGKELEAEGRLQEAEYHYLEAQEWKATVNMYRASGLWEEAYRVART :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GKHHPDLLSDTHLHLGKELEAEGRLQEAEYHYLEAQEWKATVNMYRASGLWEEAYRVART 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA1 QGGANAHKHVAYLWAKSLGGEAAVRLLNKLGLLEAAVDHAADNCSFEFAFELSRLALKHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QGGANAHKHVAYLWAKSLGGEAAVRLLNKLGLLEAAVDHAADNCSFEFAFELSRLALKHK 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA1 TPEVHLKYAMFLEDEGKFEEAEAEFIRAGKPKEAVLMFVHNQDWEAAQRVAEAHDPDSVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TPEVHLKYAMFLEDEGKFEEAEAEFIRAGKPKEAVLMFVHNQDWEAAQRVAEAHDPDSVA 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA1 EVLVGQARGALEEKDFQKAEGLLLRAQRPGLALNYYKEAGLWSDALRICKDYVPSQLEAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EVLVGQARGALEEKDFQKAEGLLLRAQRPGLALNYYKEAGLWSDALRICKDYVPSQLEAL 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA1 QEEYEREATKKGARGVEGFVEQARHWEQAGEYSRAVDCYLKVRDSGNSGLAEKCWMKAAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::.: XP_011 QEEYEREATKKGARGVEGFVEQARHWEQAGEYSRAVDCYLKVRDSGNSGLAEKCWMKVAG 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA1 LSIKFLPPQRNMEVVLAVGPQLIGIGKHSAAAELYLNLDLVKEAIDAFIEGEEWNKAKRV XP_011 IYGVPAG >>XP_016859281 (OMIM: 607386,615630,616394) PREDICTED: i (1318 aa) initn: 8182 init1: 8182 opt: 8182 Z-score: 9088.0 bits: 1694.3 E(85289): 0 Smith-Waterman score: 8196; 94.2% identity (95.6% similar) in 1340 aa overlap (1-1332:1-1313) 10 20 30 40 50 60 pF1KA1 MHLKHLRTLLSPQDGAAKVTCMAWSQNNAKFAVCTVDRVVLLYDEHGERRDKFSTKPADM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MHLKHLRTLLSPQDGAAKVTCMAWSQNNAKFAVCTVDRVVLLYDEHGERRDKFSTKPADM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 KYGRKSYMVKGMAFSPDSTKIAIGQTDNIIYVYKIGEDWGDKKVICNKFIQTSAVTCLQW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KYGRKSYMVKGMAFSPDSTKIAIGQTDNIIYVYKIGEDWGDKKVICNKFIQTSAVTCLQW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 PAEYIIVFGLAEGKVRLANTKTNKSSTIYGTESYVVSLTTNCSGKGILSGHADGTIVRYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PAEYIIVFGLAEGKVRLANTKTNKSSTIYGTESYVVSLTTNCSGKGILSGHADGTIVRYF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 FDDEGSGESQGKLVNHPCPPYALAWATNSIVAAGCDRKIVAYGKEGHMLQTFDYSRDPQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FDDEGSGESQGKLVNHPCPPYALAWATNSIVAAGCDRKIVAYGKEGHMLQTFDYSRDPQE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 REFTTAVSSPGGQSVVLGSYDRLRVFNWIPRRSIWEEAKPKEITNLYTITALAWKRDGSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REFTTAVSSPGGQSVVLGSYDRLRVFNWIPRRSIWEEAKPKEITNLYTITALAWKRDGSR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 LCVGTLCGGVEQFDCCLRRSIYKNKFELTYVGPSQVIVKNLSSGTRVVLKSHYGYEVEEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LCVGTLCGGVEQFDCCLRRSIYKNKFELTYVGPSQVIVKNLSSGTRVVLKSHYGYEVEEV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 KILGKERYLVAHTSETLLLGDLNTNRLSEIAWQGSGGNEKYFFENENVCMIFNAGELTLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KILGKERYLVAHTSETLLLGDLNTNRLSEIAWQGSGGNEKYFFENENVCMIFNAGELTLV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 EYGNNDTLGSVRTEFMNPHLISVRINERCQRGTEDNKKLAYLIDIKTIAIVDLIGGYNIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EYGNNDTLGSVRTEFMNPHLISVRINERCQRGTEDNKKLAYLIDIKTIAIVDLIGGYNIG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 TVSHESRVDWLELNETGHKLLFRDRKLRLHLYDIESCSKTMILNFCSYMQWVPGSDVLVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TVSHESRVDWLELNETGHKLLFRDRKLRLHLYDIESCSKTMILNFCSYMQWVPGSDVLVA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 QNRNSLCVWYNIEAPERVTMFTIRGDVIGLERGGGKTEVMVMEGVTTVAYTLDEGLIEFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QNRNSLCVWYNIEAPERVTMFTIRGDVIGLERGGGKTEVMVMEGVTTVAYTLDEGLIEFG 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 TAIDDGNYIRATAFLETLEMTPETEAMWKTLSKLALEARQLHIAERCFSALGQVAKARFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TAIDDGNYIRATAFLETLEMTPETEAMWKTLSKLALEARQLHIAERCFSALGQVAKARFL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 HETNEIADQVSREYGGEGTDFYQVRARLAMLEKNYKLAEMIFLEQNAVEEAMGMYQELHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HETNEIADQVSREYGGEGTDFYQVRARLAMLEKNYKLAEMIFLEQNAVEEAMGMYQELHR 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 WDECIAVAEAKGHPALEKLRRSYYQWLMDTQQEERAGELQESQGDGLAAISLYLKAGLPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WDECIAVAEAKGHPALEKLRRSYYQWLMDTQQEERAGELQESQGDGLAAISLYLKAGLPA 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 KAARLVLTREELLANTELVEHITAALIKGELYERAGDLFEKIHNPQKALECYRKGNAFMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KAARLVLTREELLANTELVEHITAALIKGELYERAGDLFEKIHNPQKALECYRKGNAFMK 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 AVELARLAFPVEVVKLEEAWGDHLVQQKQLDAAINHYIEARCSIKAIEAALGARQWKKAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVELARLAFPVEVVKLEEAWGDHLVQQKQLDAAINHYIEARCSIKAIEAALGARQWKKAI 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 YILDLQDRNTASKYYPLVAQHYASLQEYEIAEELYTKGDRTKDAIDMYTQAGRWEQAHKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YILDLQDRNTASKYYPLVAQHYASLQEYEIAEELYTKGDRTKDAIDMYTQAGRWEQAHKL 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 AMKCMRPEDVSVLYITQAQEMEKQGKYREAERLYVTVQEPDLAITMYKKHKLYDDMIRLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AMKCMRPEDVSVLYITQAQEMEKQGKYREAERLYVTVQEPDLAITMYKKHKLYDDMIRLV 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA1 GKHHPDLLSDTHLHLGKELEAEGRLQEAEYHYLEAQEWKATVNMYRASGLWEEAYRVART :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKHHPDLLSDTHLHLGKELEAEGRLQEAEYHYLEAQEWKATVNMYRASGLWEEAYRVART 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA1 QGGANAHKHVAYLWAKSLGGEAAVRLLNKLGLLEAAVDHAADNCSFEFAFELSRLALKHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QGGANAHKHVAYLWAKSLGGEAAVRLLNKLGLLEAAVDHAADNCSFEFAFELSRLALKHK 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA1 TPEVHLKYAMFLEDEGKFEEAEAEFIRAGKPKEAVLMFVHNQDWEAAQRVAEAHDPDSVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPEVHLKYAMFLEDEGKFEEAEAEFIRAGKPKEAVLMFVHNQDWEAAQRVAEAHDPDSVA 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA1 EVLVGQARGALEEKDFQKAEGLLLRAQRPGLALNYYKEAGLWSDALRICKDYVPSQLEAL ::::::::::::::::::::::::::::::::::::: : :: . : : : XP_016 EVLVGQARGALEEKDFQKAEGLLLRAQRPGLALNYYKGCG------GICG--TSSTLGAG 1210 1220 1230 1240 1250 1270 1280 1290 1300 1310 pF1KA1 QEEYEREATKKGARGVEGFVEQARHWEQ--AGEYSRAVDCYLKVRDSGNSGLAEKCWM-- . . ::. . ..:: :.: .:: : : :. .: ::: XP_016 WR-------VQPCRGL--LPQSARLWKQRPGGE----------VLDEGSRNLWSACWMIE 1260 1270 1280 1290 1320 1330 1340 1350 1360 1370 pF1KA1 ----KAAELSIKFLPPQRNMEVVLAVGPQLIGIGKHSAAAELYLNLDLVKEAIDAFIEGE :: ...:. : .... XP_016 PEPLKAIKVDIRQSPDSQKLGELDQ 1300 1310 >>XP_011531061 (OMIM: 607386,615630,616394) PREDICTED: i (1229 aa) initn: 8107 init1: 8107 opt: 8107 Z-score: 9005.1 bits: 1678.9 E(85289): 0 Smith-Waterman score: 8107; 100.0% identity (100.0% similar) in 1229 aa overlap (521-1749:1-1229) 500 510 520 530 540 550 pF1KA1 LELNETGHKLLFRDRKLRLHLYDIESCSKTMILNFCSYMQWVPGSDVLVAQNRNSLCVWY :::::::::::::::::::::::::::::: XP_011 MILNFCSYMQWVPGSDVLVAQNRNSLCVWY 10 20 30 560 570 580 590 600 610 pF1KA1 NIEAPERVTMFTIRGDVIGLERGGGKTEVMVMEGVTTVAYTLDEGLIEFGTAIDDGNYIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NIEAPERVTMFTIRGDVIGLERGGGKTEVMVMEGVTTVAYTLDEGLIEFGTAIDDGNYIR 40 50 60 70 80 90 620 630 640 650 660 670 pF1KA1 ATAFLETLEMTPETEAMWKTLSKLALEARQLHIAERCFSALGQVAKARFLHETNEIADQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ATAFLETLEMTPETEAMWKTLSKLALEARQLHIAERCFSALGQVAKARFLHETNEIADQV 100 110 120 130 140 150 680 690 700 710 720 730 pF1KA1 SREYGGEGTDFYQVRARLAMLEKNYKLAEMIFLEQNAVEEAMGMYQELHRWDECIAVAEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SREYGGEGTDFYQVRARLAMLEKNYKLAEMIFLEQNAVEEAMGMYQELHRWDECIAVAEA 160 170 180 190 200 210 740 750 760 770 780 790 pF1KA1 KGHPALEKLRRSYYQWLMDTQQEERAGELQESQGDGLAAISLYLKAGLPAKAARLVLTRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KGHPALEKLRRSYYQWLMDTQQEERAGELQESQGDGLAAISLYLKAGLPAKAARLVLTRE 220 230 240 250 260 270 800 810 820 830 840 850 pF1KA1 ELLANTELVEHITAALIKGELYERAGDLFEKIHNPQKALECYRKGNAFMKAVELARLAFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELLANTELVEHITAALIKGELYERAGDLFEKIHNPQKALECYRKGNAFMKAVELARLAFP 280 290 300 310 320 330 860 870 880 890 900 910 pF1KA1 VEVVKLEEAWGDHLVQQKQLDAAINHYIEARCSIKAIEAALGARQWKKAIYILDLQDRNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VEVVKLEEAWGDHLVQQKQLDAAINHYIEARCSIKAIEAALGARQWKKAIYILDLQDRNT 340 350 360 370 380 390 920 930 940 950 960 970 pF1KA1 ASKYYPLVAQHYASLQEYEIAEELYTKGDRTKDAIDMYTQAGRWEQAHKLAMKCMRPEDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASKYYPLVAQHYASLQEYEIAEELYTKGDRTKDAIDMYTQAGRWEQAHKLAMKCMRPEDV 400 410 420 430 440 450 980 990 1000 1010 1020 1030 pF1KA1 SVLYITQAQEMEKQGKYREAERLYVTVQEPDLAITMYKKHKLYDDMIRLVGKHHPDLLSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SVLYITQAQEMEKQGKYREAERLYVTVQEPDLAITMYKKHKLYDDMIRLVGKHHPDLLSD 460 470 480 490 500 510 1040 1050 1060 1070 1080 1090 pF1KA1 THLHLGKELEAEGRLQEAEYHYLEAQEWKATVNMYRASGLWEEAYRVARTQGGANAHKHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 THLHLGKELEAEGRLQEAEYHYLEAQEWKATVNMYRASGLWEEAYRVARTQGGANAHKHV 520 530 540 550 560 570 1100 1110 1120 1130 1140 1150 pF1KA1 AYLWAKSLGGEAAVRLLNKLGLLEAAVDHAADNCSFEFAFELSRLALKHKTPEVHLKYAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AYLWAKSLGGEAAVRLLNKLGLLEAAVDHAADNCSFEFAFELSRLALKHKTPEVHLKYAM 580 590 600 610 620 630 1160 1170 1180 1190 1200 1210 pF1KA1 FLEDEGKFEEAEAEFIRAGKPKEAVLMFVHNQDWEAAQRVAEAHDPDSVAEVLVGQARGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FLEDEGKFEEAEAEFIRAGKPKEAVLMFVHNQDWEAAQRVAEAHDPDSVAEVLVGQARGA 640 650 660 670 680 690 1220 1230 1240 1250 1260 1270 pF1KA1 LEEKDFQKAEGLLLRAQRPGLALNYYKEAGLWSDALRICKDYVPSQLEALQEEYEREATK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LEEKDFQKAEGLLLRAQRPGLALNYYKEAGLWSDALRICKDYVPSQLEALQEEYEREATK 700 710 720 730 740 750 1280 1290 1300 1310 1320 1330 pF1KA1 KGARGVEGFVEQARHWEQAGEYSRAVDCYLKVRDSGNSGLAEKCWMKAAELSIKFLPPQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KGARGVEGFVEQARHWEQAGEYSRAVDCYLKVRDSGNSGLAEKCWMKAAELSIKFLPPQR 760 770 780 790 800 810 1340 1350 1360 1370 1380 1390 pF1KA1 NMEVVLAVGPQLIGIGKHSAAAELYLNLDLVKEAIDAFIEGEEWNKAKRVAKELDPRYED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NMEVVLAVGPQLIGIGKHSAAAELYLNLDLVKEAIDAFIEGEEWNKAKRVAKELDPRYED 820 830 840 850 860 870 1400 1410 1420 1430 1440 1450 pF1KA1 YVDQHYKEFLKNQGKVDSLVGVDVIAALDLYVEQGQWDKCIETATKQNYKILHKYVALYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YVDQHYKEFLKNQGKVDSLVGVDVIAALDLYVEQGQWDKCIETATKQNYKILHKYVALYA 880 890 900 910 920 930 1460 1470 1480 1490 1500 1510 pF1KA1 THLIREGSSAQALALYVQHGAPANPQNFNIYKRIFTDMVSSPGTNCAEAYHSWADLRDVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 THLIREGSSAQALALYVQHGAPANPQNFNIYKRIFTDMVSSPGTNCAEAYHSWADLRDVL 940 950 960 970 980 990 1520 1530 1540 1550 1560 1570 pF1KA1 FNLCENLVKSSEANSPAHEEFKTMLLIAHYYATRSAAQSVKQLETVAARLSVSLLRHTQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FNLCENLVKSSEANSPAHEEFKTMLLIAHYYATRSAAQSVKQLETVAARLSVSLLRHTQL 1000 1010 1020 1030 1040 1050 1580 1590 1600 1610 1620 1630 pF1KA1 LPVDKAFYEAGIAAKAVGWDNMAFIFLNRFLDLTDAIEEGTLDGLDHSDFQDTDIPFEVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPVDKAFYEAGIAAKAVGWDNMAFIFLNRFLDLTDAIEEGTLDGLDHSDFQDTDIPFEVP 1060 1070 1080 1090 1100 1110 1640 1650 1660 1670 1680 1690 pF1KA1 LPAKQHVPEAEREEVRDWVLTVSMDQRLEQVLPRDERGAYEASLVAASTGVRALPCLITG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPAKQHVPEAEREEVRDWVLTVSMDQRLEQVLPRDERGAYEASLVAASTGVRALPCLITG 1120 1130 1140 1150 1160 1170 1700 1710 1720 1730 1740 pF1KA1 YPILRNKIEFKRPGKAANKDNWNKFLMAIKTSHSPVCQDVLKFISQWCGGLPSTSFSFQ ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YPILRNKIEFKRPGKAANKDNWNKFLMAIKTSHSPVCQDVLKFISQWCGGLPSTSFSFQ 1180 1190 1200 1210 1220 >>XP_016859279 (OMIM: 607386,615630,616394) PREDICTED: i (1706 aa) initn: 8039 init1: 8039 opt: 8039 Z-score: 8927.5 bits: 1665.0 E(85289): 0 Smith-Waterman score: 11237; 98.7% identity (98.7% similar) in 1728 aa overlap (22-1749:1-1706) 10 20 30 40 50 60 pF1KA1 MHLKHLRTLLSPQDGAAKVTCMAWSQNNAKFAVCTVDRVVLLYDEHGERRDKFSTKPADM ::::::::::::::::::::::::::::::::::::::: XP_016 MAWSQNNAKFAVCTVDRVVLLYDEHGERRDKFSTKPADM 10 20 30 70 80 90 100 110 120 pF1KA1 KYGRKSYMVKGMAFSPDSTKIAIGQTDNIIYVYKIGEDWGDKKVICNKFIQTSAVTCLQW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KYGRKSYMVKGMAFSPDSTKIAIGQTDNIIYVYKIGEDWGDKKVICNKFIQTSAVTCLQW 40 50 60 70 80 90 130 140 150 160 170 180 pF1KA1 PAEYIIVFGLAEGKVRLANTKTNKSSTIYGTESYVVSLTTNCSGKGILSGHADGTIVRYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PAEYIIVFGLAEGKVRLANTKTNKSSTIYGTESYVVSLTTNCSGKGILSGHADGTIVRYF 100 110 120 130 140 150 190 200 210 220 230 240 pF1KA1 FDDEGSGESQGKLVNHPCPPYALAWATNSIVAAGCDRKIVAYGKEGHMLQTFDYSRDPQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FDDEGSGESQGKLVNHPCPPYALAWATNSIVAAGCDRKIVAYGKEGHMLQTFDYSRDPQE 160 170 180 190 200 210 250 260 270 280 290 300 pF1KA1 REFTTAVSSPGGQSVVLGSYDRLRVFNWIPRRSIWEEAKPKEITNLYTITALAWKRDGSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REFTTAVSSPGGQSVVLGSYDRLRVFNWIPRRSIWEEAKPKEITNLYTITALAWKRDGSR 220 230 240 250 260 270 310 320 330 340 350 360 pF1KA1 LCVGTLCGGVEQFDCCLRRSIYKNKFELTYVGPSQVIVKNLSSGTRVVLKSHYGYEVEEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LCVGTLCGGVEQFDCCLRRSIYKNKFELTYVGPSQVIVKNLSSGTRVVLKSHYGYEVEEV 280 290 300 310 320 330 370 380 390 400 410 420 pF1KA1 KILGKERYLVAHTSETLLLGDLNTNRLSEIAWQGSGGNEKYFFENENVCMIFNAGELTLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KILGKERYLVAHTSETLLLGDLNTNRLSEIAWQGSGGNEKYFFENENVCMIFNAGELTLV 340 350 360 370 380 390 430 440 450 460 470 480 pF1KA1 EYGNNDTLGSVRTEFMNPHLISVRINERCQRGTEDNKKLAYLIDIKTIAIVDLIGGYNIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EYGNNDTLGSVRTEFMNPHLISVRINERCQRGTEDNKKLAYLIDIKTIAIVDLIGGYNIG 400 410 420 430 440 450 490 500 510 520 530 540 pF1KA1 TVSHESRVDWLELNETGHKLLFRDRKLRLHLYDIESCSKTMILNFCSYMQWVPGSDVLVA :::::::::::::::::::::::::::: :::::::::: XP_016 TVSHESRVDWLELNETGHKLLFRDRKLR----------------------WVPGSDVLVA 460 470 480 490 550 560 570 580 590 600 pF1KA1 QNRNSLCVWYNIEAPERVTMFTIRGDVIGLERGGGKTEVMVMEGVTTVAYTLDEGLIEFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QNRNSLCVWYNIEAPERVTMFTIRGDVIGLERGGGKTEVMVMEGVTTVAYTLDEGLIEFG 500 510 520 530 540 550 610 620 630 640 650 660 pF1KA1 TAIDDGNYIRATAFLETLEMTPETEAMWKTLSKLALEARQLHIAERCFSALGQVAKARFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TAIDDGNYIRATAFLETLEMTPETEAMWKTLSKLALEARQLHIAERCFSALGQVAKARFL 560 570 580 590 600 610 670 680 690 700 710 720 pF1KA1 HETNEIADQVSREYGGEGTDFYQVRARLAMLEKNYKLAEMIFLEQNAVEEAMGMYQELHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HETNEIADQVSREYGGEGTDFYQVRARLAMLEKNYKLAEMIFLEQNAVEEAMGMYQELHR 620 630 640 650 660 670 730 740 750 760 770 780 pF1KA1 WDECIAVAEAKGHPALEKLRRSYYQWLMDTQQEERAGELQESQGDGLAAISLYLKAGLPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WDECIAVAEAKGHPALEKLRRSYYQWLMDTQQEERAGELQESQGDGLAAISLYLKAGLPA 680 690 700 710 720 730 790 800 810 820 830 840 pF1KA1 KAARLVLTREELLANTELVEHITAALIKGELYERAGDLFEKIHNPQKALECYRKGNAFMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KAARLVLTREELLANTELVEHITAALIKGELYERAGDLFEKIHNPQKALECYRKGNAFMK 740 750 760 770 780 790 850 860 870 880 890 900 pF1KA1 AVELARLAFPVEVVKLEEAWGDHLVQQKQLDAAINHYIEARCSIKAIEAALGARQWKKAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVELARLAFPVEVVKLEEAWGDHLVQQKQLDAAINHYIEARCSIKAIEAALGARQWKKAI 800 810 820 830 840 850 910 920 930 940 950 960 pF1KA1 YILDLQDRNTASKYYPLVAQHYASLQEYEIAEELYTKGDRTKDAIDMYTQAGRWEQAHKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YILDLQDRNTASKYYPLVAQHYASLQEYEIAEELYTKGDRTKDAIDMYTQAGRWEQAHKL 860 870 880 890 900 910 970 980 990 1000 1010 1020 pF1KA1 AMKCMRPEDVSVLYITQAQEMEKQGKYREAERLYVTVQEPDLAITMYKKHKLYDDMIRLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AMKCMRPEDVSVLYITQAQEMEKQGKYREAERLYVTVQEPDLAITMYKKHKLYDDMIRLV 920 930 940 950 960 970 1030 1040 1050 1060 1070 1080 pF1KA1 GKHHPDLLSDTHLHLGKELEAEGRLQEAEYHYLEAQEWKATVNMYRASGLWEEAYRVART :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKHHPDLLSDTHLHLGKELEAEGRLQEAEYHYLEAQEWKATVNMYRASGLWEEAYRVART 980 990 1000 1010 1020 1030 1090 1100 1110 1120 1130 1140 pF1KA1 QGGANAHKHVAYLWAKSLGGEAAVRLLNKLGLLEAAVDHAADNCSFEFAFELSRLALKHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QGGANAHKHVAYLWAKSLGGEAAVRLLNKLGLLEAAVDHAADNCSFEFAFELSRLALKHK 1040 1050 1060 1070 1080 1090 1150 1160 1170 1180 1190 1200 pF1KA1 TPEVHLKYAMFLEDEGKFEEAEAEFIRAGKPKEAVLMFVHNQDWEAAQRVAEAHDPDSVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPEVHLKYAMFLEDEGKFEEAEAEFIRAGKPKEAVLMFVHNQDWEAAQRVAEAHDPDSVA 1100 1110 1120 1130 1140 1150 1210 1220 1230 1240 1250 1260 pF1KA1 EVLVGQARGALEEKDFQKAEGLLLRAQRPGLALNYYKEAGLWSDALRICKDYVPSQLEAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EVLVGQARGALEEKDFQKAEGLLLRAQRPGLALNYYKEAGLWSDALRICKDYVPSQLEAL 1160 1170 1180 1190 1200 1210 1270 1280 1290 1300 1310 1320 pF1KA1 QEEYEREATKKGARGVEGFVEQARHWEQAGEYSRAVDCYLKVRDSGNSGLAEKCWMKAAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QEEYEREATKKGARGVEGFVEQARHWEQAGEYSRAVDCYLKVRDSGNSGLAEKCWMKAAE 1220 1230 1240 1250 1260 1270 1330 1340 1350 1360 1370 1380 pF1KA1 LSIKFLPPQRNMEVVLAVGPQLIGIGKHSAAAELYLNLDLVKEAIDAFIEGEEWNKAKRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSIKFLPPQRNMEVVLAVGPQLIGIGKHSAAAELYLNLDLVKEAIDAFIEGEEWNKAKRV 1280 1290 1300 1310 1320 1330 1390 1400 1410 1420 1430 1440 pF1KA1 AKELDPRYEDYVDQHYKEFLKNQGKVDSLVGVDVIAALDLYVEQGQWDKCIETATKQNYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AKELDPRYEDYVDQHYKEFLKNQGKVDSLVGVDVIAALDLYVEQGQWDKCIETATKQNYK 1340 1350 1360 1370 1380 1390 1450 1460 1470 1480 1490 1500 pF1KA1 ILHKYVALYATHLIREGSSAQALALYVQHGAPANPQNFNIYKRIFTDMVSSPGTNCAEAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILHKYVALYATHLIREGSSAQALALYVQHGAPANPQNFNIYKRIFTDMVSSPGTNCAEAY 1400 1410 1420 1430 1440 1450 1510 1520 1530 1540 1550 1560 pF1KA1 HSWADLRDVLFNLCENLVKSSEANSPAHEEFKTMLLIAHYYATRSAAQSVKQLETVAARL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HSWADLRDVLFNLCENLVKSSEANSPAHEEFKTMLLIAHYYATRSAAQSVKQLETVAARL 1460 1470 1480 1490 1500 1510 1570 1580 1590 1600 1610 1620 pF1KA1 SVSLLRHTQLLPVDKAFYEAGIAAKAVGWDNMAFIFLNRFLDLTDAIEEGTLDGLDHSDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVSLLRHTQLLPVDKAFYEAGIAAKAVGWDNMAFIFLNRFLDLTDAIEEGTLDGLDHSDF 1520 1530 1540 1550 1560 1570 1630 1640 1650 1660 1670 1680 pF1KA1 QDTDIPFEVPLPAKQHVPEAEREEVRDWVLTVSMDQRLEQVLPRDERGAYEASLVAASTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QDTDIPFEVPLPAKQHVPEAEREEVRDWVLTVSMDQRLEQVLPRDERGAYEASLVAASTG 1580 1590 1600 1610 1620 1630 1690 1700 1710 1720 1730 1740 pF1KA1 VRALPCLITGYPILRNKIEFKRPGKAANKDNWNKFLMAIKTSHSPVCQDVLKFISQWCGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VRALPCLITGYPILRNKIEFKRPGKAANKDNWNKFLMAIKTSHSPVCQDVLKFISQWCGG 1640 1650 1660 1670 1680 1690 pF1KA1 LPSTSFSFQ ::::::::: XP_016 LPSTSFSFQ 1700 >>XP_005264311 (OMIM: 607386,615630,616394) PREDICTED: i (1727 aa) initn: 8039 init1: 8039 opt: 8039 Z-score: 8927.4 bits: 1665.0 E(85289): 0 Smith-Waterman score: 11379; 98.7% identity (98.7% similar) in 1749 aa overlap (1-1749:1-1727) 10 20 30 40 50 60 pF1KA1 MHLKHLRTLLSPQDGAAKVTCMAWSQNNAKFAVCTVDRVVLLYDEHGERRDKFSTKPADM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MHLKHLRTLLSPQDGAAKVTCMAWSQNNAKFAVCTVDRVVLLYDEHGERRDKFSTKPADM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 KYGRKSYMVKGMAFSPDSTKIAIGQTDNIIYVYKIGEDWGDKKVICNKFIQTSAVTCLQW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KYGRKSYMVKGMAFSPDSTKIAIGQTDNIIYVYKIGEDWGDKKVICNKFIQTSAVTCLQW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 PAEYIIVFGLAEGKVRLANTKTNKSSTIYGTESYVVSLTTNCSGKGILSGHADGTIVRYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PAEYIIVFGLAEGKVRLANTKTNKSSTIYGTESYVVSLTTNCSGKGILSGHADGTIVRYF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 FDDEGSGESQGKLVNHPCPPYALAWATNSIVAAGCDRKIVAYGKEGHMLQTFDYSRDPQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FDDEGSGESQGKLVNHPCPPYALAWATNSIVAAGCDRKIVAYGKEGHMLQTFDYSRDPQE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 REFTTAVSSPGGQSVVLGSYDRLRVFNWIPRRSIWEEAKPKEITNLYTITALAWKRDGSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 REFTTAVSSPGGQSVVLGSYDRLRVFNWIPRRSIWEEAKPKEITNLYTITALAWKRDGSR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 LCVGTLCGGVEQFDCCLRRSIYKNKFELTYVGPSQVIVKNLSSGTRVVLKSHYGYEVEEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LCVGTLCGGVEQFDCCLRRSIYKNKFELTYVGPSQVIVKNLSSGTRVVLKSHYGYEVEEV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 KILGKERYLVAHTSETLLLGDLNTNRLSEIAWQGSGGNEKYFFENENVCMIFNAGELTLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KILGKERYLVAHTSETLLLGDLNTNRLSEIAWQGSGGNEKYFFENENVCMIFNAGELTLV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 EYGNNDTLGSVRTEFMNPHLISVRINERCQRGTEDNKKLAYLIDIKTIAIVDLIGGYNIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EYGNNDTLGSVRTEFMNPHLISVRINERCQRGTEDNKKLAYLIDIKTIAIVDLIGGYNIG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 TVSHESRVDWLELNETGHKLLFRDRKLRLHLYDIESCSKTMILNFCSYMQWVPGSDVLVA :::::::::::::::::::::::::::: :::::::::: XP_005 TVSHESRVDWLELNETGHKLLFRDRKLR----------------------WVPGSDVLVA 490 500 510 550 560 570 580 590 600 pF1KA1 QNRNSLCVWYNIEAPERVTMFTIRGDVIGLERGGGKTEVMVMEGVTTVAYTLDEGLIEFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QNRNSLCVWYNIEAPERVTMFTIRGDVIGLERGGGKTEVMVMEGVTTVAYTLDEGLIEFG 520 530 540 550 560 570 610 620 630 640 650 660 pF1KA1 TAIDDGNYIRATAFLETLEMTPETEAMWKTLSKLALEARQLHIAERCFSALGQVAKARFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TAIDDGNYIRATAFLETLEMTPETEAMWKTLSKLALEARQLHIAERCFSALGQVAKARFL 580 590 600 610 620 630 670 680 690 700 710 720 pF1KA1 HETNEIADQVSREYGGEGTDFYQVRARLAMLEKNYKLAEMIFLEQNAVEEAMGMYQELHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HETNEIADQVSREYGGEGTDFYQVRARLAMLEKNYKLAEMIFLEQNAVEEAMGMYQELHR 640 650 660 670 680 690 730 740 750 760 770 780 pF1KA1 WDECIAVAEAKGHPALEKLRRSYYQWLMDTQQEERAGELQESQGDGLAAISLYLKAGLPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WDECIAVAEAKGHPALEKLRRSYYQWLMDTQQEERAGELQESQGDGLAAISLYLKAGLPA 700 710 720 730 740 750 790 800 810 820 830 840 pF1KA1 KAARLVLTREELLANTELVEHITAALIKGELYERAGDLFEKIHNPQKALECYRKGNAFMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KAARLVLTREELLANTELVEHITAALIKGELYERAGDLFEKIHNPQKALECYRKGNAFMK 760 770 780 790 800 810 850 860 870 880 890 900 pF1KA1 AVELARLAFPVEVVKLEEAWGDHLVQQKQLDAAINHYIEARCSIKAIEAALGARQWKKAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AVELARLAFPVEVVKLEEAWGDHLVQQKQLDAAINHYIEARCSIKAIEAALGARQWKKAI 820 830 840 850 860 870 910 920 930 940 950 960 pF1KA1 YILDLQDRNTASKYYPLVAQHYASLQEYEIAEELYTKGDRTKDAIDMYTQAGRWEQAHKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YILDLQDRNTASKYYPLVAQHYASLQEYEIAEELYTKGDRTKDAIDMYTQAGRWEQAHKL 880 890 900 910 920 930 970 980 990 1000 1010 1020 pF1KA1 AMKCMRPEDVSVLYITQAQEMEKQGKYREAERLYVTVQEPDLAITMYKKHKLYDDMIRLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AMKCMRPEDVSVLYITQAQEMEKQGKYREAERLYVTVQEPDLAITMYKKHKLYDDMIRLV 940 950 960 970 980 990 1030 1040 1050 1060 1070 1080 pF1KA1 GKHHPDLLSDTHLHLGKELEAEGRLQEAEYHYLEAQEWKATVNMYRASGLWEEAYRVART :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GKHHPDLLSDTHLHLGKELEAEGRLQEAEYHYLEAQEWKATVNMYRASGLWEEAYRVART 1000 1010 1020 1030 1040 1050 1090 1100 1110 1120 1130 1140 pF1KA1 QGGANAHKHVAYLWAKSLGGEAAVRLLNKLGLLEAAVDHAADNCSFEFAFELSRLALKHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QGGANAHKHVAYLWAKSLGGEAAVRLLNKLGLLEAAVDHAADNCSFEFAFELSRLALKHK 1060 1070 1080 1090 1100 1110 1150 1160 1170 1180 1190 1200 pF1KA1 TPEVHLKYAMFLEDEGKFEEAEAEFIRAGKPKEAVLMFVHNQDWEAAQRVAEAHDPDSVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TPEVHLKYAMFLEDEGKFEEAEAEFIRAGKPKEAVLMFVHNQDWEAAQRVAEAHDPDSVA 1120 1130 1140 1150 1160 1170 1210 1220 1230 1240 1250 1260 pF1KA1 EVLVGQARGALEEKDFQKAEGLLLRAQRPGLALNYYKEAGLWSDALRICKDYVPSQLEAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EVLVGQARGALEEKDFQKAEGLLLRAQRPGLALNYYKEAGLWSDALRICKDYVPSQLEAL 1180 1190 1200 1210 1220 1230 1270 1280 1290 1300 1310 1320 pF1KA1 QEEYEREATKKGARGVEGFVEQARHWEQAGEYSRAVDCYLKVRDSGNSGLAEKCWMKAAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QEEYEREATKKGARGVEGFVEQARHWEQAGEYSRAVDCYLKVRDSGNSGLAEKCWMKAAE 1240 1250 1260 1270 1280 1290 1330 1340 1350 1360 1370 1380 pF1KA1 LSIKFLPPQRNMEVVLAVGPQLIGIGKHSAAAELYLNLDLVKEAIDAFIEGEEWNKAKRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LSIKFLPPQRNMEVVLAVGPQLIGIGKHSAAAELYLNLDLVKEAIDAFIEGEEWNKAKRV 1300 1310 1320 1330 1340 1350 1390 1400 1410 1420 1430 1440 pF1KA1 AKELDPRYEDYVDQHYKEFLKNQGKVDSLVGVDVIAALDLYVEQGQWDKCIETATKQNYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AKELDPRYEDYVDQHYKEFLKNQGKVDSLVGVDVIAALDLYVEQGQWDKCIETATKQNYK 1360 1370 1380 1390 1400 1410 1450 1460 1470 1480 1490 1500 pF1KA1 ILHKYVALYATHLIREGSSAQALALYVQHGAPANPQNFNIYKRIFTDMVSSPGTNCAEAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ILHKYVALYATHLIREGSSAQALALYVQHGAPANPQNFNIYKRIFTDMVSSPGTNCAEAY 1420 1430 1440 1450 1460 1470 1510 1520 1530 1540 1550 1560 pF1KA1 HSWADLRDVLFNLCENLVKSSEANSPAHEEFKTMLLIAHYYATRSAAQSVKQLETVAARL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HSWADLRDVLFNLCENLVKSSEANSPAHEEFKTMLLIAHYYATRSAAQSVKQLETVAARL 1480 1490 1500 1510 1520 1530 1570 1580 1590 1600 1610 1620 pF1KA1 SVSLLRHTQLLPVDKAFYEAGIAAKAVGWDNMAFIFLNRFLDLTDAIEEGTLDGLDHSDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SVSLLRHTQLLPVDKAFYEAGIAAKAVGWDNMAFIFLNRFLDLTDAIEEGTLDGLDHSDF 1540 1550 1560 1570 1580 1590 1630 1640 1650 1660 1670 1680 pF1KA1 QDTDIPFEVPLPAKQHVPEAEREEVRDWVLTVSMDQRLEQVLPRDERGAYEASLVAASTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QDTDIPFEVPLPAKQHVPEAEREEVRDWVLTVSMDQRLEQVLPRDERGAYEASLVAASTG 1600 1610 1620 1630 1640 1650 1690 1700 1710 1720 1730 1740 pF1KA1 VRALPCLITGYPILRNKIEFKRPGKAANKDNWNKFLMAIKTSHSPVCQDVLKFISQWCGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VRALPCLITGYPILRNKIEFKRPGKAANKDNWNKFLMAIKTSHSPVCQDVLKFISQWCGG 1660 1670 1680 1690 1700 1710 pF1KA1 LPSTSFSFQ ::::::::: XP_005 LPSTSFSFQ 1720 1749 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 20:42:02 2016 done: Wed Nov 2 20:42:04 2016 Total Scan time: 12.480 Total Display time: 0.800 Function used was FASTA [36.3.4 Apr, 2011]