FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1189, 284 aa 1>>>pF1KA1189 284 - 284 aa - 284 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.5021+/-0.000335; mu= 5.7719+/- 0.021 mean_var=149.9929+/-29.362, 0's: 0 Z-trim(119.0): 28 B-trim: 0 in 0/60 Lambda= 0.104722 statistics sampled from 32605 (32633) to 32605 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.736), E-opt: 0.2 (0.383), width: 16 Scan time: 7.640 The best scores are: opt bits E(85289) NP_001291273 (OMIM: 610072) ermin isoform b [Homo ( 284) 1886 296.2 4.8e-80 NP_065762 (OMIM: 610072) ermin isoform b [Homo sap ( 284) 1886 296.2 4.8e-80 NP_001291274 (OMIM: 610072) ermin isoform b [Homo ( 284) 1886 296.2 4.8e-80 NP_001009959 (OMIM: 610072) ermin isoform a [Homo ( 297) 1886 296.2 4.9e-80 NP_001291275 (OMIM: 610072) ermin isoform c [Homo ( 264) 1263 202.0 9.7e-52 >>NP_001291273 (OMIM: 610072) ermin isoform b [Homo sapi (284 aa) initn: 1886 init1: 1886 opt: 1886 Z-score: 1558.1 bits: 296.2 E(85289): 4.8e-80 Smith-Waterman score: 1886; 100.0% identity (100.0% similar) in 284 aa overlap (1-284:1-284) 10 20 30 40 50 60 pF1KA1 MTDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MTDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 RRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 SGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 VWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDE 190 200 210 220 230 240 250 260 270 280 pF1KA1 QPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESMMHL :::::::::::::::::::::::::::::::::::::::::::: NP_001 QPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESMMHL 250 260 270 280 >>NP_065762 (OMIM: 610072) ermin isoform b [Homo sapiens (284 aa) initn: 1886 init1: 1886 opt: 1886 Z-score: 1558.1 bits: 296.2 E(85289): 4.8e-80 Smith-Waterman score: 1886; 100.0% identity (100.0% similar) in 284 aa overlap (1-284:1-284) 10 20 30 40 50 60 pF1KA1 MTDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 MTDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 RRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 RRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 SGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 SGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 VWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 VWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDE 190 200 210 220 230 240 250 260 270 280 pF1KA1 QPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESMMHL :::::::::::::::::::::::::::::::::::::::::::: NP_065 QPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESMMHL 250 260 270 280 >>NP_001291274 (OMIM: 610072) ermin isoform b [Homo sapi (284 aa) initn: 1886 init1: 1886 opt: 1886 Z-score: 1558.1 bits: 296.2 E(85289): 4.8e-80 Smith-Waterman score: 1886; 100.0% identity (100.0% similar) in 284 aa overlap (1-284:1-284) 10 20 30 40 50 60 pF1KA1 MTDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MTDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 RRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 SGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 VWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDE 190 200 210 220 230 240 250 260 270 280 pF1KA1 QPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESMMHL :::::::::::::::::::::::::::::::::::::::::::: NP_001 QPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESMMHL 250 260 270 280 >>NP_001009959 (OMIM: 610072) ermin isoform a [Homo sapi (297 aa) initn: 1886 init1: 1886 opt: 1886 Z-score: 1557.8 bits: 296.2 E(85289): 4.9e-80 Smith-Waterman score: 1886; 100.0% identity (100.0% similar) in 284 aa overlap (1-284:14-297) 10 20 30 40 pF1KA1 MTDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEP ::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKTLSPDRIQPHIMTDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEP 10 20 30 40 50 60 50 60 70 80 90 100 pF1KA1 SLEGALTKGSQEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLEGALTKGSQEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEM 70 80 90 100 110 120 110 120 130 140 150 160 pF1KA1 TFREGHQWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TFREGHQWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQ 130 140 150 160 170 180 170 180 190 200 210 220 pF1KA1 ADMLHSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ADMLHSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSP 190 200 210 220 230 240 230 240 250 260 270 280 pF1KA1 LSSASSQAVTPDEQPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESMMHL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSSASSQAVTPDEQPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESMMHL 250 260 270 280 290 >>NP_001291275 (OMIM: 610072) ermin isoform c [Homo sapi (264 aa) initn: 1242 init1: 1242 opt: 1263 Z-score: 1049.9 bits: 202.0 E(85289): 9.7e-52 Smith-Waterman score: 1711; 93.0% identity (93.0% similar) in 284 aa overlap (1-284:1-264) 10 20 30 40 50 60 pF1KA1 MTDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MTDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 RRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPL ::::::::::::::::::::: ::::::::::::::::::: NP_001 RRKLQGNMLLNSSMEDKMLKE--------------------TSADEMTFREGHQWEKIPL 70 80 90 100 130 140 150 160 170 180 pF1KA1 SGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQK 110 120 130 140 150 160 190 200 210 220 230 240 pF1KA1 VWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDE 170 180 190 200 210 220 250 260 270 280 pF1KA1 QPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESMMHL :::::::::::::::::::::::::::::::::::::::::::: NP_001 QPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESMMHL 230 240 250 260 284 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 20:43:19 2016 done: Wed Nov 2 20:43:20 2016 Total Scan time: 7.640 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]