Result of FASTA (omim) for
pF1KA1216
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA1216, 1368 aa
1>>>pF1KA1216 1368 - 1368 aa - 1368 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3543+/-0.000457; mu= 22.1710+/- 0.029
mean_var=61.7851+/-12.177, 0's: 0 Z-trim(108.1): 34 B-trim: 0 in 0/49
Lambda= 0.163167
statistics sampled from 16153 (16164) to 16153 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.526), E-opt: 0.2 (0.19), width: 16
Scan time: 11.450
The best scores are: opt bits E(85289)
NP_004821 (OMIM: 605042,614249) mediator of RNA po (1368) 9250 2187.2 0
XP_005267280 (OMIM: 605042,614249) PREDICTED: medi (1374) 9228 2182.0 0
NP_001257451 (OMIM: 605042,614249) mediator of RNA (1364) 9198 2175.0 0
NP_001257450 (OMIM: 605042,614249) mediator of RNA (1359) 9193 2173.8 0
NP_057063 (OMIM: 605042,614249) mediator of RNA po (1365) 9171 2168.6 0
XP_011534559 (OMIM: 605042,614249) PREDICTED: medi (1336) 7291 1726.0 0
XP_016866990 (OMIM: 605042,614249) PREDICTED: medi (1057) 7159 1694.9 0
XP_006715675 (OMIM: 605042,614249) PREDICTED: medi ( 747) 4909 1165.2 0
>>NP_004821 (OMIM: 605042,614249) mediator of RNA polyme (1368 aa)
initn: 9250 init1: 9250 opt: 9250 Z-score: 11753.5 bits: 2187.2 E(85289): 0
Smith-Waterman score: 9250; 100.0% identity (100.0% similar) in 1368 aa overlap (1-1368:1-1368)
10 20 30 40 50 60
pF1KA1 METQLQSIFEEVVKTEVIEEAFPGMFMDTPEDEKTKLISCLGAFRQFWGGLSQESHEQCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 METQLQSIFEEVVKTEVIEEAFPGMFMDTPEDEKTKLISCLGAFRQFWGGLSQESHEQCI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 QWIVKFIHGQHSPKRISFLYDCLAMAVETGLLPPRLVCESLINSDTLEWERTQLWALTFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QWIVKFIHGQHSPKRISFLYDCLAMAVETGLLPPRLVCESLINSDTLEWERTQLWALTFK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 LVRKIIGGVDYKGVRDLLKVILEKILTIPNTVSSAVVQQLLAAREVIAYILERNACLLPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LVRKIIGGVDYKGVRDLLKVILEKILTIPNTVSSAVVQQLLAAREVIAYILERNACLLPA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 YFAVTEIRKLYPEGKLPHWLLGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGAICNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 YFAVTEIRKLYPEGKLPHWLLGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGAICNS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 WKLDPATLRFPLKGLLPYDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQHKQRCPVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 WKLDPATLRFPLKGLLPYDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQHKQRCPVL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 EDQLVDLVVYAMERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EDQLVDLVVYAMERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 AGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKEYIPVPDINKPQST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 AGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKEYIPVPDINKPQST
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 HAFAMTCIWIHLNRKAQNDNSKLQIPIPHSLRLHHEFLQQSLRNKSLQMNDYKIALLCNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 HAFAMTCIWIHLNRKAQNDNSKLQIPIPHSLRLHHEFLQQSLRNKSLQMNDYKIALLCNA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 YSTNSECFTLPMGALVETIYGNGIMRIPLPGTNCMASGSITPLPMNLLDSLTVHAKMSLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 YSTNSECFTLPMGALVETIYGNGIMRIPLPGTNCMASGSITPLPMNLLDSLTVHAKMSLI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 HSIATRVIKLAHAKSSVALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 HSIATRVIKLAHAKSSVALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 LHTLLEMFSYRMHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLITALGSSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LHTLLEMFSYRMHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLITALGSSE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 VQPQFTRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VQPQFTRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIM
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 SFTPHNWASHTLSCFPGPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMSNENDIITHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SFTPHNWASHTLSCFPGPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMSNENDIITHF
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA1 SMQGSPPLFLCLLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SMQGSPPLFLCLLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA1 QQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRV
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA1 SDFVKENSPEHWLQNDWHTKHMNYHKKYPEKLYFEGLAEQVDPPVQIQSPYLPIYFGNVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SDFVKENSPEHWLQNDWHTKHMNYHKKYPEKLYFEGLAEQVDPPVQIQSPYLPIYFGNVC
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA1 LRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEMHLRDRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEMHLRDRA
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA1 FLKRKLVHAIIGSLKDNRPQGWCLSDTYLKCAMNAREENPWVPDDTYYCRLIGRLVDTMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FLKRKLVHAIIGSLKDNRPQGWCLSDTYLKCAMNAREENPWVPDDTYYCRLIGRLVDTMA
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA1 GKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVSGKEVGNALLNVVLKSQPLVPRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVSGKEVGNALLNVVLKSQPLVPRE
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA1 NITAWMNAIGLIITALPEPYWIVLHDRIVSVISSPSLTSETEWVGYPFRLFDFTACHQSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NITAWMNAIGLIITALPEPYWIVLHDRIVSVISSPSLTSETEWVGYPFRLFDFTACHQSY
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA1 SEMSCSYTLALAHAVWHHSSIGQLSLIPKFLTEVLLPIVKTEFQLLYVYHLVGPFLQRFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SEMSCSYTLALAHAVWHHSSIGQLSLIPKFLTEVLLPIVKTEFQLLYVYHLVGPFLQRFQ
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA1 QERTRCMIEIGVAFYDMLLNVDQCSTHLNYMDPICDFLYHMKYMFTGDSVKEQVEKIICN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QERTRCMIEIGVAFYDMLLNVDQCSTHLNYMDPICDFLYHMKYMFTGDSVKEQVEKIICN
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360
pF1KA1 LKPALKLRLRFITHISKMEPAAVPPQAMNSGSPAPQSNQVPVSLPVTQ
::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LKPALKLRLRFITHISKMEPAAVPPQAMNSGSPAPQSNQVPVSLPVTQ
1330 1340 1350 1360
>>XP_005267280 (OMIM: 605042,614249) PREDICTED: mediator (1374 aa)
initn: 7296 init1: 7296 opt: 9228 Z-score: 11725.5 bits: 2182.0 E(85289): 0
Smith-Waterman score: 9228; 99.6% identity (99.6% similar) in 1374 aa overlap (1-1368:1-1374)
10 20 30 40 50 60
pF1KA1 METQLQSIFEEVVKTEVIEEAFPGMFMDTPEDEKTKLISCLGAFRQFWGGLSQESHEQCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 METQLQSIFEEVVKTEVIEEAFPGMFMDTPEDEKTKLISCLGAFRQFWGGLSQESHEQCI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 QWIVKFIHGQHSPKRISFLYDCLAMAVETGLLPPRLVCESLINSDTLEWERTQLWALTFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QWIVKFIHGQHSPKRISFLYDCLAMAVETGLLPPRLVCESLINSDTLEWERTQLWALTFK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 LVRKIIGGVDYKGVRDLLKVILEKILTIPNTVSSAVVQQLLAAREVIAYILERNACLLPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LVRKIIGGVDYKGVRDLLKVILEKILTIPNTVSSAVVQQLLAAREVIAYILERNACLLPA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 YFAVTEIRKLYPEGKLPHWLLGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGAICNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YFAVTEIRKLYPEGKLPHWLLGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGAICNS
190 200 210 220 230 240
250 260 270 280 290
pF1KA1 WKLDPATLRFPLKGLLPYDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQ------HK
:::::::::::::::::::::::::::::::::::::::::::::::::::: ::
XP_005 WKLDPATLRFPLKGLLPYDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQTLNIAQHK
250 260 270 280 290 300
300 310 320 330 340 350
pF1KA1 QRCPVLEDQLVDLVVYAMERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QRCPVLEDQLVDLVVYAMERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVL
310 320 330 340 350 360
360 370 380 390 400 410
pF1KA1 SLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKEYIPVPDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKEYIPVPDI
370 380 390 400 410 420
420 430 440 450 460 470
pF1KA1 NKPQSTHAFAMTCIWIHLNRKAQNDNSKLQIPIPHSLRLHHEFLQQSLRNKSLQMNDYKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NKPQSTHAFAMTCIWIHLNRKAQNDNSKLQIPIPHSLRLHHEFLQQSLRNKSLQMNDYKI
430 440 450 460 470 480
480 490 500 510 520 530
pF1KA1 ALLCNAYSTNSECFTLPMGALVETIYGNGIMRIPLPGTNCMASGSITPLPMNLLDSLTVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ALLCNAYSTNSECFTLPMGALVETIYGNGIMRIPLPGTNCMASGSITPLPMNLLDSLTVH
490 500 510 520 530 540
540 550 560 570 580 590
pF1KA1 AKMSLIHSIATRVIKLAHAKSSVALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AKMSLIHSIATRVIKLAHAKSSVALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFK
550 560 570 580 590 600
600 610 620 630 640 650
pF1KA1 SHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLIT
610 620 630 640 650 660
660 670 680 690 700 710
pF1KA1 ALGSSEVQPQFTRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ALGSSEVQPQFTRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKD
670 680 690 700 710 720
720 730 740 750 760 770
pF1KA1 ILQTIMSFTPHNWASHTLSCFPGPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMSNEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ILQTIMSFTPHNWASHTLSCFPGPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMSNEN
730 740 750 760 770 780
780 790 800 810 820 830
pF1KA1 DIITHFSMQGSPPLFLCLLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DIITHFSMQGSPPLFLCLLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEF
790 800 810 820 830 840
840 850 860 870 880 890
pF1KA1 STSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 STSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPN
850 860 870 880 890 900
900 910 920 930 940 950
pF1KA1 DFRNRVSDFVKENSPEHWLQNDWHTKHMNYHKKYPEKLYFEGLAEQVDPPVQIQSPYLPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DFRNRVSDFVKENSPEHWLQNDWHTKHMNYHKKYPEKLYFEGLAEQVDPPVQIQSPYLPI
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KA1 YFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEM
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KA1 HLRDRAFLKRKLVHAIIGSLKDNRPQGWCLSDTYLKCAMNAREENPWVPDDTYYCRLIGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HLRDRAFLKRKLVHAIIGSLKDNRPQGWCLSDTYLKCAMNAREENPWVPDDTYYCRLIGR
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KA1 LVDTMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVSGKEVGNALLNVVLKSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LVDTMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVSGKEVGNALLNVVLKSQ
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170 1180 1190
pF1KA1 PLVPRENITAWMNAIGLIITALPEPYWIVLHDRIVSVISSPSLTSETEWVGYPFRLFDFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PLVPRENITAWMNAIGLIITALPEPYWIVLHDRIVSVISSPSLTSETEWVGYPFRLFDFT
1150 1160 1170 1180 1190 1200
1200 1210 1220 1230 1240 1250
pF1KA1 ACHQSYSEMSCSYTLALAHAVWHHSSIGQLSLIPKFLTEVLLPIVKTEFQLLYVYHLVGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ACHQSYSEMSCSYTLALAHAVWHHSSIGQLSLIPKFLTEVLLPIVKTEFQLLYVYHLVGP
1210 1220 1230 1240 1250 1260
1260 1270 1280 1290 1300 1310
pF1KA1 FLQRFQQERTRCMIEIGVAFYDMLLNVDQCSTHLNYMDPICDFLYHMKYMFTGDSVKEQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FLQRFQQERTRCMIEIGVAFYDMLLNVDQCSTHLNYMDPICDFLYHMKYMFTGDSVKEQV
1270 1280 1290 1300 1310 1320
1320 1330 1340 1350 1360
pF1KA1 EKIICNLKPALKLRLRFITHISKMEPAAVPPQAMNSGSPAPQSNQVPVSLPVTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKIICNLKPALKLRLRFITHISKMEPAAVPPQAMNSGSPAPQSNQVPVSLPVTQ
1330 1340 1350 1360 1370
>>NP_001257451 (OMIM: 605042,614249) mediator of RNA pol (1364 aa)
initn: 9198 init1: 9198 opt: 9198 Z-score: 11687.4 bits: 2175.0 E(85289): 0
Smith-Waterman score: 9198; 100.0% identity (100.0% similar) in 1360 aa overlap (1-1360:1-1360)
10 20 30 40 50 60
pF1KA1 METQLQSIFEEVVKTEVIEEAFPGMFMDTPEDEKTKLISCLGAFRQFWGGLSQESHEQCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 METQLQSIFEEVVKTEVIEEAFPGMFMDTPEDEKTKLISCLGAFRQFWGGLSQESHEQCI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 QWIVKFIHGQHSPKRISFLYDCLAMAVETGLLPPRLVCESLINSDTLEWERTQLWALTFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QWIVKFIHGQHSPKRISFLYDCLAMAVETGLLPPRLVCESLINSDTLEWERTQLWALTFK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 LVRKIIGGVDYKGVRDLLKVILEKILTIPNTVSSAVVQQLLAAREVIAYILERNACLLPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVRKIIGGVDYKGVRDLLKVILEKILTIPNTVSSAVVQQLLAAREVIAYILERNACLLPA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 YFAVTEIRKLYPEGKLPHWLLGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGAICNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YFAVTEIRKLYPEGKLPHWLLGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGAICNS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 WKLDPATLRFPLKGLLPYDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQHKQRCPVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WKLDPATLRFPLKGLLPYDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQHKQRCPVL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 EDQLVDLVVYAMERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDQLVDLVVYAMERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 AGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKEYIPVPDINKPQST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKEYIPVPDINKPQST
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 HAFAMTCIWIHLNRKAQNDNSKLQIPIPHSLRLHHEFLQQSLRNKSLQMNDYKIALLCNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HAFAMTCIWIHLNRKAQNDNSKLQIPIPHSLRLHHEFLQQSLRNKSLQMNDYKIALLCNA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 YSTNSECFTLPMGALVETIYGNGIMRIPLPGTNCMASGSITPLPMNLLDSLTVHAKMSLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSTNSECFTLPMGALVETIYGNGIMRIPLPGTNCMASGSITPLPMNLLDSLTVHAKMSLI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 HSIATRVIKLAHAKSSVALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HSIATRVIKLAHAKSSVALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 LHTLLEMFSYRMHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLITALGSSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHTLLEMFSYRMHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLITALGSSE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 VQPQFTRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQPQFTRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIM
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 SFTPHNWASHTLSCFPGPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMSNENDIITHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFTPHNWASHTLSCFPGPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMSNENDIITHF
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA1 SMQGSPPLFLCLLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SMQGSPPLFLCLLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA1 QQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRV
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA1 SDFVKENSPEHWLQNDWHTKHMNYHKKYPEKLYFEGLAEQVDPPVQIQSPYLPIYFGNVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDFVKENSPEHWLQNDWHTKHMNYHKKYPEKLYFEGLAEQVDPPVQIQSPYLPIYFGNVC
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA1 LRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEMHLRDRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEMHLRDRA
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA1 FLKRKLVHAIIGSLKDNRPQGWCLSDTYLKCAMNAREENPWVPDDTYYCRLIGRLVDTMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLKRKLVHAIIGSLKDNRPQGWCLSDTYLKCAMNAREENPWVPDDTYYCRLIGRLVDTMA
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA1 GKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVSGKEVGNALLNVVLKSQPLVPRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVSGKEVGNALLNVVLKSQPLVPRE
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA1 NITAWMNAIGLIITALPEPYWIVLHDRIVSVISSPSLTSETEWVGYPFRLFDFTACHQSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NITAWMNAIGLIITALPEPYWIVLHDRIVSVISSPSLTSETEWVGYPFRLFDFTACHQSY
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA1 SEMSCSYTLALAHAVWHHSSIGQLSLIPKFLTEVLLPIVKTEFQLLYVYHLVGPFLQRFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEMSCSYTLALAHAVWHHSSIGQLSLIPKFLTEVLLPIVKTEFQLLYVYHLVGPFLQRFQ
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA1 QERTRCMIEIGVAFYDMLLNVDQCSTHLNYMDPICDFLYHMKYMFTGDSVKEQVEKIICN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QERTRCMIEIGVAFYDMLLNVDQCSTHLNYMDPICDFLYHMKYMFTGDSVKEQVEKIICN
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360
pF1KA1 LKPALKLRLRFITHISKMEPAAVPPQAMNSGSPAPQSNQVPVSLPVTQ
::::::::::::::::::::::::::::::::::::::::
NP_001 LKPALKLRLRFITHISKMEPAAVPPQAMNSGSPAPQSNQVDTLT
1330 1340 1350 1360
>>NP_001257450 (OMIM: 605042,614249) mediator of RNA pol (1359 aa)
initn: 9193 init1: 9193 opt: 9193 Z-score: 11681.0 bits: 2173.8 E(85289): 0
Smith-Waterman score: 9193; 100.0% identity (100.0% similar) in 1359 aa overlap (1-1359:1-1359)
10 20 30 40 50 60
pF1KA1 METQLQSIFEEVVKTEVIEEAFPGMFMDTPEDEKTKLISCLGAFRQFWGGLSQESHEQCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 METQLQSIFEEVVKTEVIEEAFPGMFMDTPEDEKTKLISCLGAFRQFWGGLSQESHEQCI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 QWIVKFIHGQHSPKRISFLYDCLAMAVETGLLPPRLVCESLINSDTLEWERTQLWALTFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QWIVKFIHGQHSPKRISFLYDCLAMAVETGLLPPRLVCESLINSDTLEWERTQLWALTFK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 LVRKIIGGVDYKGVRDLLKVILEKILTIPNTVSSAVVQQLLAAREVIAYILERNACLLPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVRKIIGGVDYKGVRDLLKVILEKILTIPNTVSSAVVQQLLAAREVIAYILERNACLLPA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 YFAVTEIRKLYPEGKLPHWLLGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGAICNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YFAVTEIRKLYPEGKLPHWLLGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGAICNS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 WKLDPATLRFPLKGLLPYDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQHKQRCPVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WKLDPATLRFPLKGLLPYDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQHKQRCPVL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 EDQLVDLVVYAMERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDQLVDLVVYAMERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 AGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKEYIPVPDINKPQST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKEYIPVPDINKPQST
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 HAFAMTCIWIHLNRKAQNDNSKLQIPIPHSLRLHHEFLQQSLRNKSLQMNDYKIALLCNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HAFAMTCIWIHLNRKAQNDNSKLQIPIPHSLRLHHEFLQQSLRNKSLQMNDYKIALLCNA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 YSTNSECFTLPMGALVETIYGNGIMRIPLPGTNCMASGSITPLPMNLLDSLTVHAKMSLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSTNSECFTLPMGALVETIYGNGIMRIPLPGTNCMASGSITPLPMNLLDSLTVHAKMSLI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 HSIATRVIKLAHAKSSVALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HSIATRVIKLAHAKSSVALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 LHTLLEMFSYRMHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLITALGSSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHTLLEMFSYRMHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLITALGSSE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 VQPQFTRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQPQFTRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIM
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 SFTPHNWASHTLSCFPGPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMSNENDIITHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFTPHNWASHTLSCFPGPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMSNENDIITHF
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA1 SMQGSPPLFLCLLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SMQGSPPLFLCLLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA1 QQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRV
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA1 SDFVKENSPEHWLQNDWHTKHMNYHKKYPEKLYFEGLAEQVDPPVQIQSPYLPIYFGNVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDFVKENSPEHWLQNDWHTKHMNYHKKYPEKLYFEGLAEQVDPPVQIQSPYLPIYFGNVC
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA1 LRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEMHLRDRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEMHLRDRA
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA1 FLKRKLVHAIIGSLKDNRPQGWCLSDTYLKCAMNAREENPWVPDDTYYCRLIGRLVDTMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLKRKLVHAIIGSLKDNRPQGWCLSDTYLKCAMNAREENPWVPDDTYYCRLIGRLVDTMA
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA1 GKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVSGKEVGNALLNVVLKSQPLVPRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVSGKEVGNALLNVVLKSQPLVPRE
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA1 NITAWMNAIGLIITALPEPYWIVLHDRIVSVISSPSLTSETEWVGYPFRLFDFTACHQSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NITAWMNAIGLIITALPEPYWIVLHDRIVSVISSPSLTSETEWVGYPFRLFDFTACHQSY
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA1 SEMSCSYTLALAHAVWHHSSIGQLSLIPKFLTEVLLPIVKTEFQLLYVYHLVGPFLQRFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEMSCSYTLALAHAVWHHSSIGQLSLIPKFLTEVLLPIVKTEFQLLYVYHLVGPFLQRFQ
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA1 QERTRCMIEIGVAFYDMLLNVDQCSTHLNYMDPICDFLYHMKYMFTGDSVKEQVEKIICN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QERTRCMIEIGVAFYDMLLNVDQCSTHLNYMDPICDFLYHMKYMFTGDSVKEQVEKIICN
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360
pF1KA1 LKPALKLRLRFITHISKMEPAAVPPQAMNSGSPAPQSNQVPVSLPVTQ
:::::::::::::::::::::::::::::::::::::::
NP_001 LKPALKLRLRFITHISKMEPAAVPPQAMNSGSPAPQSNQ
1330 1340 1350
>>NP_057063 (OMIM: 605042,614249) mediator of RNA polyme (1365 aa)
initn: 7239 init1: 7239 opt: 9171 Z-score: 11653.0 bits: 2168.6 E(85289): 0
Smith-Waterman score: 9171; 99.6% identity (99.6% similar) in 1365 aa overlap (1-1359:1-1365)
10 20 30 40 50 60
pF1KA1 METQLQSIFEEVVKTEVIEEAFPGMFMDTPEDEKTKLISCLGAFRQFWGGLSQESHEQCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 METQLQSIFEEVVKTEVIEEAFPGMFMDTPEDEKTKLISCLGAFRQFWGGLSQESHEQCI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 QWIVKFIHGQHSPKRISFLYDCLAMAVETGLLPPRLVCESLINSDTLEWERTQLWALTFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 QWIVKFIHGQHSPKRISFLYDCLAMAVETGLLPPRLVCESLINSDTLEWERTQLWALTFK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 LVRKIIGGVDYKGVRDLLKVILEKILTIPNTVSSAVVQQLLAAREVIAYILERNACLLPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 LVRKIIGGVDYKGVRDLLKVILEKILTIPNTVSSAVVQQLLAAREVIAYILERNACLLPA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 YFAVTEIRKLYPEGKLPHWLLGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGAICNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 YFAVTEIRKLYPEGKLPHWLLGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGAICNS
190 200 210 220 230 240
250 260 270 280 290
pF1KA1 WKLDPATLRFPLKGLLPYDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQ------HK
:::::::::::::::::::::::::::::::::::::::::::::::::::: ::
NP_057 WKLDPATLRFPLKGLLPYDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQTLNIAQHK
250 260 270 280 290 300
300 310 320 330 340 350
pF1KA1 QRCPVLEDQLVDLVVYAMERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 QRCPVLEDQLVDLVVYAMERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVL
310 320 330 340 350 360
360 370 380 390 400 410
pF1KA1 SLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKEYIPVPDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 SLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKEYIPVPDI
370 380 390 400 410 420
420 430 440 450 460 470
pF1KA1 NKPQSTHAFAMTCIWIHLNRKAQNDNSKLQIPIPHSLRLHHEFLQQSLRNKSLQMNDYKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 NKPQSTHAFAMTCIWIHLNRKAQNDNSKLQIPIPHSLRLHHEFLQQSLRNKSLQMNDYKI
430 440 450 460 470 480
480 490 500 510 520 530
pF1KA1 ALLCNAYSTNSECFTLPMGALVETIYGNGIMRIPLPGTNCMASGSITPLPMNLLDSLTVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 ALLCNAYSTNSECFTLPMGALVETIYGNGIMRIPLPGTNCMASGSITPLPMNLLDSLTVH
490 500 510 520 530 540
540 550 560 570 580 590
pF1KA1 AKMSLIHSIATRVIKLAHAKSSVALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 AKMSLIHSIATRVIKLAHAKSSVALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFK
550 560 570 580 590 600
600 610 620 630 640 650
pF1KA1 SHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 SHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLIT
610 620 630 640 650 660
660 670 680 690 700 710
pF1KA1 ALGSSEVQPQFTRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 ALGSSEVQPQFTRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKD
670 680 690 700 710 720
720 730 740 750 760 770
pF1KA1 ILQTIMSFTPHNWASHTLSCFPGPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMSNEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 ILQTIMSFTPHNWASHTLSCFPGPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMSNEN
730 740 750 760 770 780
780 790 800 810 820 830
pF1KA1 DIITHFSMQGSPPLFLCLLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 DIITHFSMQGSPPLFLCLLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEF
790 800 810 820 830 840
840 850 860 870 880 890
pF1KA1 STSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 STSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPN
850 860 870 880 890 900
900 910 920 930 940 950
pF1KA1 DFRNRVSDFVKENSPEHWLQNDWHTKHMNYHKKYPEKLYFEGLAEQVDPPVQIQSPYLPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 DFRNRVSDFVKENSPEHWLQNDWHTKHMNYHKKYPEKLYFEGLAEQVDPPVQIQSPYLPI
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KA1 YFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 YFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEM
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KA1 HLRDRAFLKRKLVHAIIGSLKDNRPQGWCLSDTYLKCAMNAREENPWVPDDTYYCRLIGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 HLRDRAFLKRKLVHAIIGSLKDNRPQGWCLSDTYLKCAMNAREENPWVPDDTYYCRLIGR
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KA1 LVDTMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVSGKEVGNALLNVVLKSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 LVDTMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVSGKEVGNALLNVVLKSQ
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170 1180 1190
pF1KA1 PLVPRENITAWMNAIGLIITALPEPYWIVLHDRIVSVISSPSLTSETEWVGYPFRLFDFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 PLVPRENITAWMNAIGLIITALPEPYWIVLHDRIVSVISSPSLTSETEWVGYPFRLFDFT
1150 1160 1170 1180 1190 1200
1200 1210 1220 1230 1240 1250
pF1KA1 ACHQSYSEMSCSYTLALAHAVWHHSSIGQLSLIPKFLTEVLLPIVKTEFQLLYVYHLVGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 ACHQSYSEMSCSYTLALAHAVWHHSSIGQLSLIPKFLTEVLLPIVKTEFQLLYVYHLVGP
1210 1220 1230 1240 1250 1260
1260 1270 1280 1290 1300 1310
pF1KA1 FLQRFQQERTRCMIEIGVAFYDMLLNVDQCSTHLNYMDPICDFLYHMKYMFTGDSVKEQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 FLQRFQQERTRCMIEIGVAFYDMLLNVDQCSTHLNYMDPICDFLYHMKYMFTGDSVKEQV
1270 1280 1290 1300 1310 1320
1320 1330 1340 1350 1360
pF1KA1 EKIICNLKPALKLRLRFITHISKMEPAAVPPQAMNSGSPAPQSNQVPVSLPVTQ
:::::::::::::::::::::::::::::::::::::::::::::
NP_057 EKIICNLKPALKLRLRFITHISKMEPAAVPPQAMNSGSPAPQSNQ
1330 1340 1350 1360
>>XP_011534559 (OMIM: 605042,614249) PREDICTED: mediator (1336 aa)
initn: 7291 init1: 7291 opt: 7291 Z-score: 9261.4 bits: 1726.0 E(85289): 0
Smith-Waterman score: 8959; 97.7% identity (97.7% similar) in 1368 aa overlap (1-1368:1-1336)
10 20 30 40 50 60
pF1KA1 METQLQSIFEEVVKTEVIEEAFPGMFMDTPEDEKTKLISCLGAFRQFWGGLSQESHEQCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 METQLQSIFEEVVKTEVIEEAFPGMFMDTPEDEKTKLISCLGAFRQFWGGLSQESHEQCI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 QWIVKFIHGQHSPKRISFLYDCLAMAVETGLLPPRLVCESLINSDTLEWERTQLWALTFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QWIVKFIHGQHSPKRISFLYDCLAMAVETGLLPPRLVCESLINSDTLEWERTQLWALTFK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 LVRKIIGGVDYKGVRDLLKVILEKILTIPNTVSSAVVQQLLAAREVIAYILERNACLLPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVRKIIGGVDYKGVRDLLKVILEKILTIPNTVSSAVVQQLLAAREVIAYILERNACLLPA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 YFAVTEIRKLYPEGKLPHWLLGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGAICNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YFAVTEIRKLYPEGKLPHWLLGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGAICNS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 WKLDPATLRFPLKGLLPYDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQHKQRCPVL
:::::::::::::::::::: ::::::::
XP_011 WKLDPATLRFPLKGLLPYDK--------------------------------HKQRCPVL
250 260
310 320 330 340 350 360
pF1KA1 EDQLVDLVVYAMERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDQLVDLVVYAMERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKL
270 280 290 300 310 320
370 380 390 400 410 420
pF1KA1 AGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKEYIPVPDINKPQST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKEYIPVPDINKPQST
330 340 350 360 370 380
430 440 450 460 470 480
pF1KA1 HAFAMTCIWIHLNRKAQNDNSKLQIPIPHSLRLHHEFLQQSLRNKSLQMNDYKIALLCNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HAFAMTCIWIHLNRKAQNDNSKLQIPIPHSLRLHHEFLQQSLRNKSLQMNDYKIALLCNA
390 400 410 420 430 440
490 500 510 520 530 540
pF1KA1 YSTNSECFTLPMGALVETIYGNGIMRIPLPGTNCMASGSITPLPMNLLDSLTVHAKMSLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YSTNSECFTLPMGALVETIYGNGIMRIPLPGTNCMASGSITPLPMNLLDSLTVHAKMSLI
450 460 470 480 490 500
550 560 570 580 590 600
pF1KA1 HSIATRVIKLAHAKSSVALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSIATRVIKLAHAKSSVALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGI
510 520 530 540 550 560
610 620 630 640 650 660
pF1KA1 LHTLLEMFSYRMHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLITALGSSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHTLLEMFSYRMHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLITALGSSE
570 580 590 600 610 620
670 680 690 700 710 720
pF1KA1 VQPQFTRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQPQFTRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIM
630 640 650 660 670 680
730 740 750 760 770 780
pF1KA1 SFTPHNWASHTLSCFPGPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMSNENDIITHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFTPHNWASHTLSCFPGPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMSNENDIITHF
690 700 710 720 730 740
790 800 810 820 830 840
pF1KA1 SMQGSPPLFLCLLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SMQGSPPLFLCLLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGG
750 760 770 780 790 800
850 860 870 880 890 900
pF1KA1 QQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRV
810 820 830 840 850 860
910 920 930 940 950 960
pF1KA1 SDFVKENSPEHWLQNDWHTKHMNYHKKYPEKLYFEGLAEQVDPPVQIQSPYLPIYFGNVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDFVKENSPEHWLQNDWHTKHMNYHKKYPEKLYFEGLAEQVDPPVQIQSPYLPIYFGNVC
870 880 890 900 910 920
970 980 990 1000 1010 1020
pF1KA1 LRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEMHLRDRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEMHLRDRA
930 940 950 960 970 980
1030 1040 1050 1060 1070 1080
pF1KA1 FLKRKLVHAIIGSLKDNRPQGWCLSDTYLKCAMNAREENPWVPDDTYYCRLIGRLVDTMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLKRKLVHAIIGSLKDNRPQGWCLSDTYLKCAMNAREENPWVPDDTYYCRLIGRLVDTMA
990 1000 1010 1020 1030 1040
1090 1100 1110 1120 1130 1140
pF1KA1 GKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVSGKEVGNALLNVVLKSQPLVPRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVSGKEVGNALLNVVLKSQPLVPRE
1050 1060 1070 1080 1090 1100
1150 1160 1170 1180 1190 1200
pF1KA1 NITAWMNAIGLIITALPEPYWIVLHDRIVSVISSPSLTSETEWVGYPFRLFDFTACHQSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NITAWMNAIGLIITALPEPYWIVLHDRIVSVISSPSLTSETEWVGYPFRLFDFTACHQSY
1110 1120 1130 1140 1150 1160
1210 1220 1230 1240 1250 1260
pF1KA1 SEMSCSYTLALAHAVWHHSSIGQLSLIPKFLTEVLLPIVKTEFQLLYVYHLVGPFLQRFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEMSCSYTLALAHAVWHHSSIGQLSLIPKFLTEVLLPIVKTEFQLLYVYHLVGPFLQRFQ
1170 1180 1190 1200 1210 1220
1270 1280 1290 1300 1310 1320
pF1KA1 QERTRCMIEIGVAFYDMLLNVDQCSTHLNYMDPICDFLYHMKYMFTGDSVKEQVEKIICN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QERTRCMIEIGVAFYDMLLNVDQCSTHLNYMDPICDFLYHMKYMFTGDSVKEQVEKIICN
1230 1240 1250 1260 1270 1280
1330 1340 1350 1360
pF1KA1 LKPALKLRLRFITHISKMEPAAVPPQAMNSGSPAPQSNQVPVSLPVTQ
::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKPALKLRLRFITHISKMEPAAVPPQAMNSGSPAPQSNQVPVSLPVTQ
1290 1300 1310 1320 1330
>>XP_016866990 (OMIM: 605042,614249) PREDICTED: mediator (1057 aa)
initn: 7159 init1: 7159 opt: 7159 Z-score: 9095.1 bits: 1694.9 E(85289): 0
Smith-Waterman score: 7159; 100.0% identity (100.0% similar) in 1057 aa overlap (312-1368:1-1057)
290 300 310 320 330 340
pF1KA1 MVCNMLGLNKQHKQRCPVLEDQLVDLVVYAMERSETEEKFDDGGTSQLLWQHLSSQLIFF
::::::::::::::::::::::::::::::
XP_016 MERSETEEKFDDGGTSQLLWQHLSSQLIFF
10 20 30
350 360 370 380 390 400
pF1KA1 VLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDL
40 50 60 70 80 90
410 420 430 440 450 460
pF1KA1 LYPEKEYIPVPDINKPQSTHAFAMTCIWIHLNRKAQNDNSKLQIPIPHSLRLHHEFLQQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYPEKEYIPVPDINKPQSTHAFAMTCIWIHLNRKAQNDNSKLQIPIPHSLRLHHEFLQQS
100 110 120 130 140 150
470 480 490 500 510 520
pF1KA1 LRNKSLQMNDYKIALLCNAYSTNSECFTLPMGALVETIYGNGIMRIPLPGTNCMASGSIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRNKSLQMNDYKIALLCNAYSTNSECFTLPMGALVETIYGNGIMRIPLPGTNCMASGSIT
160 170 180 190 200 210
530 540 550 560 570 580
pF1KA1 PLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKSSVALAPALVETYSRLLVYMEIESLGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKSSVALAPALVETYSRLLVYMEIESLGI
220 230 240 250 260 270
590 600 610 620 630 640
pF1KA1 KGFISQLLPTVFKSHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHTLAAVAQTNQNQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGFISQLLPTVFKSHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHTLAAVAQTNQNQL
280 290 300 310 320 330
650 660 670 680 690 700
pF1KA1 HLCVESTALRLITALGSSEVQPQFTRFLSDPKTVLSAESEELNRALILTLARATHVTDFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HLCVESTALRLITALGSSEVQPQFTRFLSDPKTVLSAESEELNRALILTLARATHVTDFF
340 350 360 370 380 390
710 720 730 740 750 760
pF1KA1 TGSDSIQGTWCKDILQTIMSFTPHNWASHTLSCFPGPLQAFFKQNNVPQESRFNLKKNVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGSDSIQGTWCKDILQTIMSFTPHNWASHTLSCFPGPLQAFFKQNNVPQESRFNLKKNVE
400 410 420 430 440 450
770 780 790 800 810 820
pF1KA1 EEYRKWKSMSNENDIITHFSMQGSPPLFLCLLWKMLLETDHINQIGYRVLERIGARALVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEYRKWKSMSNENDIITHFSMQGSPPLFLCLLWKMLLETDHINQIGYRVLERIGARALVA
460 470 480 490 500 510
830 840 850 860 870 880
pF1KA1 HVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQV
520 530 540 550 560 570
890 900 910 920 930 940
pF1KA1 CYFIIQLLLLKPNDFRNRVSDFVKENSPEHWLQNDWHTKHMNYHKKYPEKLYFEGLAEQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CYFIIQLLLLKPNDFRNRVSDFVKENSPEHWLQNDWHTKHMNYHKKYPEKLYFEGLAEQV
580 590 600 610 620 630
950 960 970 980 990 1000
pF1KA1 DPPVQIQSPYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPPVQIQSPYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRP
640 650 660 670 680 690
1010 1020 1030 1040 1050 1060
pF1KA1 VTYLYNTLHYYEMHLRDRAFLKRKLVHAIIGSLKDNRPQGWCLSDTYLKCAMNAREENPW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTYLYNTLHYYEMHLRDRAFLKRKLVHAIIGSLKDNRPQGWCLSDTYLKCAMNAREENPW
700 710 720 730 740 750
1070 1080 1090 1100 1110 1120
pF1KA1 VPDDTYYCRLIGRLVDTMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVSGKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPDDTYYCRLIGRLVDTMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVSGKE
760 770 780 790 800 810
1130 1140 1150 1160 1170 1180
pF1KA1 VGNALLNVVLKSQPLVPRENITAWMNAIGLIITALPEPYWIVLHDRIVSVISSPSLTSET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGNALLNVVLKSQPLVPRENITAWMNAIGLIITALPEPYWIVLHDRIVSVISSPSLTSET
820 830 840 850 860 870
1190 1200 1210 1220 1230 1240
pF1KA1 EWVGYPFRLFDFTACHQSYSEMSCSYTLALAHAVWHHSSIGQLSLIPKFLTEVLLPIVKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EWVGYPFRLFDFTACHQSYSEMSCSYTLALAHAVWHHSSIGQLSLIPKFLTEVLLPIVKT
880 890 900 910 920 930
1250 1260 1270 1280 1290 1300
pF1KA1 EFQLLYVYHLVGPFLQRFQQERTRCMIEIGVAFYDMLLNVDQCSTHLNYMDPICDFLYHM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EFQLLYVYHLVGPFLQRFQQERTRCMIEIGVAFYDMLLNVDQCSTHLNYMDPICDFLYHM
940 950 960 970 980 990
1310 1320 1330 1340 1350 1360
pF1KA1 KYMFTGDSVKEQVEKIICNLKPALKLRLRFITHISKMEPAAVPPQAMNSGSPAPQSNQVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KYMFTGDSVKEQVEKIICNLKPALKLRLRFITHISKMEPAAVPPQAMNSGSPAPQSNQVP
1000 1010 1020 1030 1040 1050
pF1KA1 VSLPVTQ
:::::::
XP_016 VSLPVTQ
>>XP_006715675 (OMIM: 605042,614249) PREDICTED: mediator (747 aa)
initn: 2977 init1: 2977 opt: 4909 Z-score: 6235.0 bits: 1165.2 E(85289): 0
Smith-Waterman score: 4909; 99.2% identity (99.2% similar) in 746 aa overlap (1-740:1-746)
10 20 30 40 50 60
pF1KA1 METQLQSIFEEVVKTEVIEEAFPGMFMDTPEDEKTKLISCLGAFRQFWGGLSQESHEQCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 METQLQSIFEEVVKTEVIEEAFPGMFMDTPEDEKTKLISCLGAFRQFWGGLSQESHEQCI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 QWIVKFIHGQHSPKRISFLYDCLAMAVETGLLPPRLVCESLINSDTLEWERTQLWALTFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QWIVKFIHGQHSPKRISFLYDCLAMAVETGLLPPRLVCESLINSDTLEWERTQLWALTFK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 LVRKIIGGVDYKGVRDLLKVILEKILTIPNTVSSAVVQQLLAAREVIAYILERNACLLPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LVRKIIGGVDYKGVRDLLKVILEKILTIPNTVSSAVVQQLLAAREVIAYILERNACLLPA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 YFAVTEIRKLYPEGKLPHWLLGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGAICNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YFAVTEIRKLYPEGKLPHWLLGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGAICNS
190 200 210 220 230 240
250 260 270 280 290
pF1KA1 WKLDPATLRFPLKGLLPYDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQ------HK
:::::::::::::::::::::::::::::::::::::::::::::::::::: ::
XP_006 WKLDPATLRFPLKGLLPYDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQTLNIAQHK
250 260 270 280 290 300
300 310 320 330 340 350
pF1KA1 QRCPVLEDQLVDLVVYAMERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QRCPVLEDQLVDLVVYAMERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVL
310 320 330 340 350 360
360 370 380 390 400 410
pF1KA1 SLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKEYIPVPDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKEYIPVPDI
370 380 390 400 410 420
420 430 440 450 460 470
pF1KA1 NKPQSTHAFAMTCIWIHLNRKAQNDNSKLQIPIPHSLRLHHEFLQQSLRNKSLQMNDYKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NKPQSTHAFAMTCIWIHLNRKAQNDNSKLQIPIPHSLRLHHEFLQQSLRNKSLQMNDYKI
430 440 450 460 470 480
480 490 500 510 520 530
pF1KA1 ALLCNAYSTNSECFTLPMGALVETIYGNGIMRIPLPGTNCMASGSITPLPMNLLDSLTVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ALLCNAYSTNSECFTLPMGALVETIYGNGIMRIPLPGTNCMASGSITPLPMNLLDSLTVH
490 500 510 520 530 540
540 550 560 570 580 590
pF1KA1 AKMSLIHSIATRVIKLAHAKSSVALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AKMSLIHSIATRVIKLAHAKSSVALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFK
550 560 570 580 590 600
600 610 620 630 640 650
pF1KA1 SHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLIT
610 620 630 640 650 660
660 670 680 690 700 710
pF1KA1 ALGSSEVQPQFTRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ALGSSEVQPQFTRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKD
670 680 690 700 710 720
720 730 740 750 760 770
pF1KA1 ILQTIMSFTPHNWASHTLSCFPGPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMSNEN
::::::::::::::::::::::::::
XP_006 ILQTIMSFTPHNWASHTLSCFPGPLQN
730 740
1368 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 20:46:58 2016 done: Wed Nov 2 20:47:00 2016
Total Scan time: 11.450 Total Display time: 0.460
Function used was FASTA [36.3.4 Apr, 2011]