Result of FASTA (omim) for
pF1KA1230
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA1230, 1011 aa
1>>>pF1KA1230 1011 - 1011 aa - 1011 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.7910+/-0.000507; mu= -3.8551+/- 0.031
mean_var=394.0211+/-82.220, 0's: 0 Z-trim(117.6): 157 B-trim: 70 in 1/57
Lambda= 0.064612
statistics sampled from 29643 (29800) to 29643 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.685), E-opt: 0.2 (0.349), width: 16
Scan time: 13.450
The best scores are: opt bits E(85289)
NP_803193 (OMIM: 603141) liprin-beta-1 isoform 2 [ (1011) 6606 631.5 6.9e-180
XP_016875551 (OMIM: 603141) PREDICTED: liprin-beta (1014) 6586 629.6 2.5e-179
XP_016875552 (OMIM: 603141) PREDICTED: liprin-beta (1004) 5744 551.1 1.1e-155
XP_016875549 (OMIM: 603141) PREDICTED: liprin-beta (1015) 5712 548.2 8.5e-155
NP_001185844 (OMIM: 603141) liprin-beta-1 isoform ( 858) 5611 538.7 5.2e-152
XP_016875563 (OMIM: 603141) PREDICTED: liprin-beta ( 861) 5595 537.2 1.5e-151
NP_001185845 (OMIM: 603141) liprin-beta-1 isoform ( 980) 5104 491.5 9.5e-138
XP_016875561 (OMIM: 603141) PREDICTED: liprin-beta ( 983) 5081 489.3 4.2e-137
XP_016875550 (OMIM: 603141) PREDICTED: liprin-beta (1022) 4757 459.1 5.4e-128
XP_016875559 (OMIM: 603141) PREDICTED: liprin-beta ( 991) 4742 457.7 1.4e-127
XP_016875548 (OMIM: 603141) PREDICTED: liprin-beta (1025) 4741 457.7 1.5e-127
XP_016875557 (OMIM: 603141) PREDICTED: liprin-beta ( 994) 4721 455.8 5.4e-127
XP_016875564 (OMIM: 603141) PREDICTED: liprin-beta ( 841) 4716 455.2 6.6e-127
NP_003613 (OMIM: 603141) liprin-beta-1 isoform 1 [ (1005) 4702 454.0 1.8e-126
XP_016875547 (OMIM: 603141) PREDICTED: liprin-beta (1023) 4343 420.6 2.2e-116
XP_005253565 (OMIM: 603141) PREDICTED: liprin-beta (1026) 4325 418.9 7.1e-116
XP_016875555 (OMIM: 603141) PREDICTED: liprin-beta ( 995) 4307 417.2 2.2e-115
XP_016875560 (OMIM: 603141) PREDICTED: liprin-beta ( 984) 4207 407.9 1.4e-112
XP_016875562 (OMIM: 603141) PREDICTED: liprin-beta ( 981) 3939 382.9 4.7e-105
XP_016875554 (OMIM: 603141) PREDICTED: liprin-beta (1001) 3594 350.7 2.3e-95
XP_006719222 (OMIM: 603141) PREDICTED: liprin-beta ( 883) 3386 331.3 1.4e-89
XP_016875546 (OMIM: 603141) PREDICTED: liprin-beta (1036) 3386 331.4 1.6e-89
XP_016875545 (OMIM: 603141) PREDICTED: liprin-beta (1036) 3386 331.4 1.6e-89
XP_005253562 (OMIM: 603141) PREDICTED: liprin-beta (1036) 3386 331.4 1.6e-89
XP_005253564 (OMIM: 603141) PREDICTED: liprin-beta (1033) 3278 321.3 1.7e-86
XP_005253566 (OMIM: 603141) PREDICTED: liprin-beta (1025) 3265 320.1 3.9e-86
XP_016875553 (OMIM: 603141) PREDICTED: liprin-beta (1002) 3249 318.6 1.1e-85
XP_016875556 (OMIM: 603141) PREDICTED: liprin-beta ( 994) 3245 318.2 1.4e-85
XP_016875558 (OMIM: 603141) PREDICTED: liprin-beta ( 991) 3234 317.2 2.9e-85
XP_016875565 (OMIM: 603141) PREDICTED: liprin-beta ( 687) 3206 314.4 1.4e-84
XP_016875566 (OMIM: 603141) PREDICTED: liprin-beta ( 580) 1923 194.7 1.2e-48
XP_006718414 (OMIM: 603142) PREDICTED: liprin-beta ( 850) 1730 176.9 4.1e-43
XP_011518719 (OMIM: 603142) PREDICTED: liprin-beta ( 858) 1730 176.9 4.1e-43
XP_006718412 (OMIM: 603142) PREDICTED: liprin-beta ( 927) 1730 176.9 4.4e-43
XP_011518716 (OMIM: 603142) PREDICTED: liprin-beta ( 927) 1730 176.9 4.4e-43
XP_011518715 (OMIM: 603142) PREDICTED: liprin-beta ( 927) 1730 176.9 4.4e-43
XP_006718416 (OMIM: 603142) PREDICTED: liprin-beta ( 784) 1726 176.5 5e-43
XP_011518721 (OMIM: 603142) PREDICTED: liprin-beta ( 769) 1718 175.7 8.3e-43
XP_011518722 (OMIM: 603142) PREDICTED: liprin-beta ( 769) 1718 175.7 8.3e-43
XP_011518720 (OMIM: 603142) PREDICTED: liprin-beta ( 815) 1718 175.8 8.6e-43
XP_016873936 (OMIM: 603142) PREDICTED: liprin-beta ( 750) 1714 175.4 1.1e-42
XP_006718415 (OMIM: 603142) PREDICTED: liprin-beta ( 839) 1678 172.0 1.2e-41
XP_005253234 (OMIM: 603142) PREDICTED: liprin-beta ( 916) 1678 172.1 1.2e-41
XP_011518718 (OMIM: 603142) PREDICTED: liprin-beta ( 897) 1635 168.1 2e-40
XP_016873933 (OMIM: 603142) PREDICTED: liprin-beta ( 810) 1627 167.3 3.1e-40
XP_006718413 (OMIM: 603142) PREDICTED: liprin-beta ( 887) 1627 167.3 3.3e-40
XP_011518717 (OMIM: 603142) PREDICTED: liprin-beta ( 900) 1620 166.7 5.2e-40
NP_003612 (OMIM: 603142) liprin-beta-2 isoform 1 [ ( 876) 1586 163.5 4.6e-39
NP_001243497 (OMIM: 603142) liprin-beta-2 isoform ( 764) 1575 162.4 8.5e-39
XP_016873935 (OMIM: 603142) PREDICTED: liprin-beta ( 799) 1575 162.4 8.8e-39
>>NP_803193 (OMIM: 603141) liprin-beta-1 isoform 2 [Homo (1011 aa)
initn: 6606 init1: 6606 opt: 6606 Z-score: 3350.5 bits: 631.5 E(85289): 6.9e-180
Smith-Waterman score: 6606; 100.0% identity (100.0% similar) in 1011 aa overlap (1-1011:1-1011)
10 20 30 40 50 60
pF1KA1 MMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGSLRALHLVEDLRGLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_803 MMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGSLRALHLVEDLRGLLE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 MMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARLENDKESLVLQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_803 MMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARLENDKESLVLQV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 SVLTDQVEAQGEKIRDLEFCLEEHREKLNATEEMLQQELLSRTSLETQKLDLMAEISNLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_803 SVLTDQVEAQGEKIRDLEFCLEEHREKLNATEEMLQQELLSRTSLETQKLDLMAEISNLK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKSLMAKLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_803 LKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKSLMAKLSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 MKIKVGQMQYEKQRMEQKWESLKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_803 MKIKVGQMQYEKQRMEQKWESLKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 RDIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGKDGEYEELLNSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_803 RDIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGKDGEYEELLNSS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 SISSLLDAQGFSDLEKSPSPTPVMGSPSCDPFNTSVPEEFHTTILQVSIPSLLPATVSME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_803 SISSLLDAQGFSDLEKSPSPTPVMGSPSCDPFNTSVPEEFHTTILQVSIPSLLPATVSME
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 TSEKSKLTPKPETSFEENDGNIILGATVDTQLCDKLLTSSLQKSSSLGNLKKETSDGEKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_803 TSEKSKLTPKPETSFEENDGNIILGATVDTQLCDKLLTSSLQKSSSLGNLKKETSDGEKE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 TIQKTSEDRAPAESRPFGTLPPRPPGQDTSMDDNPFGTRKVRSSFGRGFFKIKSNKRTAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_803 TIQKTSEDRAPAESRPFGTLPPRPPGQDTSMDDNPFGTRKVRSSFGRGFFKIKSNKRTAS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 APNLAETEKETAEHLDLAGASSRPKDSQRNSPFQIPPPSPDSKKKSRGIMKLFGKLRRSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_803 APNLAETEKETAEHLDLAGASSRPKDSQRNSPFQIPPPSPDSKKKSRGIMKLFGKLRRSQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 STTFNPDDMSEPEFKRGGTRATAGPRLGWSRDLGQSNSDLDMPFAKWTKEQVCNWLMEQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_803 STTFNPDDMSEPEFKRGGTRATAGPRLGWSRDLGQSNSDLDMPFAKWTKEQVCNWLMEQG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 LGSYLNSGKHWIASGQTLLQASQQDLEKELGIKHSLHRKKLQLALQALGSEEETNHGKLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_803 LGSYLNSGKHWIASGQTLLQASQQDLEKELGIKHSLHRKKLQLALQALGSEEETNHGKLD
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 FNWVTRWLDDIGLPQYKTQFDEGRVDGRMLHYMTVDDLLSLKVVSVLHHLSIKRAIQVLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_803 FNWVTRWLDDIGLPQYKTQFDEGRVDGRMLHYMTVDDLLSLKVVSVLHHLSIKRAIQVLR
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA1 INNFEPNCLRRRPSDENTIAPSEVQKWTNHRVMEWLRSVDLAEYAPNLRGSGVHGGLMVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_803 INNFEPNCLRRRPSDENTIAPSEVQKWTNHRVMEWLRSVDLAEYAPNLRGSGVHGGLMVL
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA1 EPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLIGAEAQHQKRDAMELPDYVLLTATAKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_803 EPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLIGAEAQHQKRDAMELPDYVLLTATAKV
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA1 KPKKLAFSNFGNLRKKKQEDGEEYVCPMELGQASGSASKKGFKPGLDMRLYEEDDLDRLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_803 KPKKLAFSNFGNLRKKKQEDGEEYVCPMELGQASGSASKKGFKPGLDMRLYEEDDLDRLE
910 920 930 940 950 960
970 980 990 1000 1010
pF1KA1 QMEDSEGTVRQIGAFSEGINNLTHMLKEDDMFKDFAARSPSASITDEDSNV
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_803 QMEDSEGTVRQIGAFSEGINNLTHMLKEDDMFKDFAARSPSASITDEDSNV
970 980 990 1000 1010
>>XP_016875551 (OMIM: 603141) PREDICTED: liprin-beta-1 i (1014 aa)
initn: 4413 init1: 4413 opt: 6586 Z-score: 3340.4 bits: 629.6 E(85289): 2.5e-179
Smith-Waterman score: 6586; 99.6% identity (99.7% similar) in 1014 aa overlap (1-1011:1-1014)
10 20 30 40 50 60
pF1KA1 MMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGSLRALHLVEDLRGLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGSLRALHLVEDLRGLLE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 MMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARLENDKESLVLQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARLENDKESLVLQV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 SVLTDQVEAQGEKIRDLEFCLEEHREKLNATEEMLQQELLSRTSLETQKLDLMAEISNLK
:::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::
XP_016 SVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQKLDLMAEISNLK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKSLMAKLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKSLMAKLSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 MKIKVGQMQYEKQRMEQKWESLKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKIKVGQMQYEKQRMEQKWESLKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVD
250 260 270 280 290 300
310 320 330 340 350
pF1KA1 RDIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGK---DGEYEELL
::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::
XP_016 RDIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGKKGKDGEYEELL
310 320 330 340 350 360
360 370 380 390 400 410
pF1KA1 NSSSISSLLDAQGFSDLEKSPSPTPVMGSPSCDPFNTSVPEEFHTTILQVSIPSLLPATV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSSSISSLLDAQGFSDLEKSPSPTPVMGSPSCDPFNTSVPEEFHTTILQVSIPSLLPATV
370 380 390 400 410 420
420 430 440 450 460 470
pF1KA1 SMETSEKSKLTPKPETSFEENDGNIILGATVDTQLCDKLLTSSLQKSSSLGNLKKETSDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SMETSEKSKLTPKPETSFEENDGNIILGATVDTQLCDKLLTSSLQKSSSLGNLKKETSDG
430 440 450 460 470 480
480 490 500 510 520 530
pF1KA1 EKETIQKTSEDRAPAESRPFGTLPPRPPGQDTSMDDNPFGTRKVRSSFGRGFFKIKSNKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKETIQKTSEDRAPAESRPFGTLPPRPPGQDTSMDDNPFGTRKVRSSFGRGFFKIKSNKR
490 500 510 520 530 540
540 550 560 570 580 590
pF1KA1 TASAPNLAETEKETAEHLDLAGASSRPKDSQRNSPFQIPPPSPDSKKKSRGIMKLFGKLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TASAPNLAETEKETAEHLDLAGASSRPKDSQRNSPFQIPPPSPDSKKKSRGIMKLFGKLR
550 560 570 580 590 600
600 610 620 630 640 650
pF1KA1 RSQSTTFNPDDMSEPEFKRGGTRATAGPRLGWSRDLGQSNSDLDMPFAKWTKEQVCNWLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSQSTTFNPDDMSEPEFKRGGTRATAGPRLGWSRDLGQSNSDLDMPFAKWTKEQVCNWLM
610 620 630 640 650 660
660 670 680 690 700 710
pF1KA1 EQGLGSYLNSGKHWIASGQTLLQASQQDLEKELGIKHSLHRKKLQLALQALGSEEETNHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQGLGSYLNSGKHWIASGQTLLQASQQDLEKELGIKHSLHRKKLQLALQALGSEEETNHG
670 680 690 700 710 720
720 730 740 750 760 770
pF1KA1 KLDFNWVTRWLDDIGLPQYKTQFDEGRVDGRMLHYMTVDDLLSLKVVSVLHHLSIKRAIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLDFNWVTRWLDDIGLPQYKTQFDEGRVDGRMLHYMTVDDLLSLKVVSVLHHLSIKRAIQ
730 740 750 760 770 780
780 790 800 810 820 830
pF1KA1 VLRINNFEPNCLRRRPSDENTIAPSEVQKWTNHRVMEWLRSVDLAEYAPNLRGSGVHGGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLRINNFEPNCLRRRPSDENTIAPSEVQKWTNHRVMEWLRSVDLAEYAPNLRGSGVHGGL
790 800 810 820 830 840
840 850 860 870 880 890
pF1KA1 MVLEPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLIGAEAQHQKRDAMELPDYVLLTAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVLEPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLIGAEAQHQKRDAMELPDYVLLTAT
850 860 870 880 890 900
900 910 920 930 940 950
pF1KA1 AKVKPKKLAFSNFGNLRKKKQEDGEEYVCPMELGQASGSASKKGFKPGLDMRLYEEDDLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKVKPKKLAFSNFGNLRKKKQEDGEEYVCPMELGQASGSASKKGFKPGLDMRLYEEDDLD
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KA1 RLEQMEDSEGTVRQIGAFSEGINNLTHMLKEDDMFKDFAARSPSASITDEDSNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLEQMEDSEGTVRQIGAFSEGINNLTHMLKEDDMFKDFAARSPSASITDEDSNV
970 980 990 1000 1010
>>XP_016875552 (OMIM: 603141) PREDICTED: liprin-beta-1 i (1004 aa)
initn: 5726 init1: 3527 opt: 5744 Z-score: 2916.3 bits: 551.1 E(85289): 1.1e-155
Smith-Waterman score: 6499; 98.6% identity (98.7% similar) in 1014 aa overlap (1-1011:1-1004)
10 20 30 40 50 60
pF1KA1 MMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGSLRALHLVEDLRGLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGSLRALHLVEDLRGLLE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 MMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARLENDKESLVLQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARLENDKESLVLQV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 SVLTDQVEAQGEKIRDLEFCLEEHREKLNATEEMLQQELLSRTSLETQKLDLMAEISNLK
:::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::
XP_016 SVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQKLDLMAEISNLK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKSLMAKLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKSLMAKLSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 MKIKVGQMQYEKQRMEQKWESLKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKIKVGQMQYEKQRMEQKWESLKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVD
250 260 270 280 290 300
310 320 330 340 350
pF1KA1 RDIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGK---DGEYEELL
::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::
XP_016 RDIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGKKGKDGEYEELL
310 320 330 340 350 360
360 370 380 390 400 410
pF1KA1 NSSSISSLLDAQGFSDLEKSPSPTPVMGSPSCDPFNTSVPEEFHTTILQVSIPSLLPATV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSSSISSLLDAQGFSDLEKSPSPTPVMGSPSCDPFNTSVPEEFHTTILQVSIPSLLPATV
370 380 390 400 410 420
420 430 440 450 460 470
pF1KA1 SMETSEKSKLTPKPETSFEENDGNIILGATVDTQLCDKLLTSSLQKSSSLGNLKKETSDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SMETSEKSKLTPKPETSFEENDGNIILGATVDTQLCDKLLTSSLQKSSSLGNLKKETSDG
430 440 450 460 470 480
480 490 500 510 520 530
pF1KA1 EKETIQKTSEDRAPAESRPFGTLPPRPPGQDTSMDDNPFGTRKVRSSFGRGFFKIKSNKR
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ----------DRAPAESRPFGTLPPRPPGQDTSMDDNPFGTRKVRSSFGRGFFKIKSNKR
490 500 510 520 530
540 550 560 570 580 590
pF1KA1 TASAPNLAETEKETAEHLDLAGASSRPKDSQRNSPFQIPPPSPDSKKKSRGIMKLFGKLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TASAPNLAETEKETAEHLDLAGASSRPKDSQRNSPFQIPPPSPDSKKKSRGIMKLFGKLR
540 550 560 570 580 590
600 610 620 630 640 650
pF1KA1 RSQSTTFNPDDMSEPEFKRGGTRATAGPRLGWSRDLGQSNSDLDMPFAKWTKEQVCNWLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSQSTTFNPDDMSEPEFKRGGTRATAGPRLGWSRDLGQSNSDLDMPFAKWTKEQVCNWLM
600 610 620 630 640 650
660 670 680 690 700 710
pF1KA1 EQGLGSYLNSGKHWIASGQTLLQASQQDLEKELGIKHSLHRKKLQLALQALGSEEETNHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQGLGSYLNSGKHWIASGQTLLQASQQDLEKELGIKHSLHRKKLQLALQALGSEEETNHG
660 670 680 690 700 710
720 730 740 750 760 770
pF1KA1 KLDFNWVTRWLDDIGLPQYKTQFDEGRVDGRMLHYMTVDDLLSLKVVSVLHHLSIKRAIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLDFNWVTRWLDDIGLPQYKTQFDEGRVDGRMLHYMTVDDLLSLKVVSVLHHLSIKRAIQ
720 730 740 750 760 770
780 790 800 810 820 830
pF1KA1 VLRINNFEPNCLRRRPSDENTIAPSEVQKWTNHRVMEWLRSVDLAEYAPNLRGSGVHGGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLRINNFEPNCLRRRPSDENTIAPSEVQKWTNHRVMEWLRSVDLAEYAPNLRGSGVHGGL
780 790 800 810 820 830
840 850 860 870 880 890
pF1KA1 MVLEPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLIGAEAQHQKRDAMELPDYVLLTAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVLEPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLIGAEAQHQKRDAMELPDYVLLTAT
840 850 860 870 880 890
900 910 920 930 940 950
pF1KA1 AKVKPKKLAFSNFGNLRKKKQEDGEEYVCPMELGQASGSASKKGFKPGLDMRLYEEDDLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKVKPKKLAFSNFGNLRKKKQEDGEEYVCPMELGQASGSASKKGFKPGLDMRLYEEDDLD
900 910 920 930 940 950
960 970 980 990 1000 1010
pF1KA1 RLEQMEDSEGTVRQIGAFSEGINNLTHMLKEDDMFKDFAARSPSASITDEDSNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLEQMEDSEGTVRQIGAFSEGINNLTHMLKEDDMFKDFAARSPSASITDEDSNV
960 970 980 990 1000
>>XP_016875549 (OMIM: 603141) PREDICTED: liprin-beta-1 i (1015 aa)
initn: 5427 init1: 3527 opt: 5712 Z-score: 2900.1 bits: 548.2 E(85289): 8.5e-155
Smith-Waterman score: 6467; 97.6% identity (97.7% similar) in 1025 aa overlap (1-1011:1-1015)
10 20 30 40 50 60
pF1KA1 MMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGSLRALHLVEDLRGLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGSLRALHLVEDLRGLLE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 MMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARLENDKESLVLQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARLENDKESLVLQV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 SVLTDQVEAQGEKIRDLEFCLEEHREKLNATEEMLQQELLSRTSLETQKLDLMAEISNLK
:::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::
XP_016 SVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQKLDLMAEISNLK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKSLMAKLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKSLMAKLSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 MKIKVGQMQYEKQRMEQKWESLKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKIKVGQMQYEKQRMEQKWESLKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVD
250 260 270 280 290 300
310 320 330 340
pF1KA1 RD-----------IEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGK
:: :::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDENFKKKLKEKNIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGK
310 320 330 340 350 360
350 360 370 380 390 400
pF1KA1 ---DGEYEELLNSSSISSLLDAQGFSDLEKSPSPTPVMGSPSCDPFNTSVPEEFHTTILQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGKDGEYEELLNSSSISSLLDAQGFSDLEKSPSPTPVMGSPSCDPFNTSVPEEFHTTILQ
370 380 390 400 410 420
410 420 430 440 450 460
pF1KA1 VSIPSLLPATVSMETSEKSKLTPKPETSFEENDGNIILGATVDTQLCDKLLTSSLQKSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSIPSLLPATVSMETSEKSKLTPKPETSFEENDGNIILGATVDTQLCDKLLTSSLQKSSS
430 440 450 460 470 480
470 480 490 500 510 520
pF1KA1 LGNLKKETSDGEKETIQKTSEDRAPAESRPFGTLPPRPPGQDTSMDDNPFGTRKVRSSFG
::::::::::: :::::::::::::::::::::::::::::::::::::::
XP_016 LGNLKKETSDG----------DRAPAESRPFGTLPPRPPGQDTSMDDNPFGTRKVRSSFG
490 500 510 520 530
530 540 550 560 570 580
pF1KA1 RGFFKIKSNKRTASAPNLAETEKETAEHLDLAGASSRPKDSQRNSPFQIPPPSPDSKKKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGFFKIKSNKRTASAPNLAETEKETAEHLDLAGASSRPKDSQRNSPFQIPPPSPDSKKKS
540 550 560 570 580 590
590 600 610 620 630 640
pF1KA1 RGIMKLFGKLRRSQSTTFNPDDMSEPEFKRGGTRATAGPRLGWSRDLGQSNSDLDMPFAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGIMKLFGKLRRSQSTTFNPDDMSEPEFKRGGTRATAGPRLGWSRDLGQSNSDLDMPFAK
600 610 620 630 640 650
650 660 670 680 690 700
pF1KA1 WTKEQVCNWLMEQGLGSYLNSGKHWIASGQTLLQASQQDLEKELGIKHSLHRKKLQLALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WTKEQVCNWLMEQGLGSYLNSGKHWIASGQTLLQASQQDLEKELGIKHSLHRKKLQLALQ
660 670 680 690 700 710
710 720 730 740 750 760
pF1KA1 ALGSEEETNHGKLDFNWVTRWLDDIGLPQYKTQFDEGRVDGRMLHYMTVDDLLSLKVVSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALGSEEETNHGKLDFNWVTRWLDDIGLPQYKTQFDEGRVDGRMLHYMTVDDLLSLKVVSV
720 730 740 750 760 770
770 780 790 800 810 820
pF1KA1 LHHLSIKRAIQVLRINNFEPNCLRRRPSDENTIAPSEVQKWTNHRVMEWLRSVDLAEYAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHHLSIKRAIQVLRINNFEPNCLRRRPSDENTIAPSEVQKWTNHRVMEWLRSVDLAEYAP
780 790 800 810 820 830
830 840 850 860 870 880
pF1KA1 NLRGSGVHGGLMVLEPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLIGAEAQHQKRDAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLRGSGVHGGLMVLEPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLIGAEAQHQKRDAM
840 850 860 870 880 890
890 900 910 920 930 940
pF1KA1 ELPDYVLLTATAKVKPKKLAFSNFGNLRKKKQEDGEEYVCPMELGQASGSASKKGFKPGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELPDYVLLTATAKVKPKKLAFSNFGNLRKKKQEDGEEYVCPMELGQASGSASKKGFKPGL
900 910 920 930 940 950
950 960 970 980 990 1000
pF1KA1 DMRLYEEDDLDRLEQMEDSEGTVRQIGAFSEGINNLTHMLKEDDMFKDFAARSPSASITD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DMRLYEEDDLDRLEQMEDSEGTVRQIGAFSEGINNLTHMLKEDDMFKDFAARSPSASITD
960 970 980 990 1000 1010
1010
pF1KA1 EDSNV
:::::
XP_016 EDSNV
>>NP_001185844 (OMIM: 603141) liprin-beta-1 isoform 3 [H (858 aa)
initn: 5611 init1: 5611 opt: 5611 Z-score: 2850.1 bits: 538.7 E(85289): 5.2e-152
Smith-Waterman score: 5611; 100.0% identity (100.0% similar) in 858 aa overlap (154-1011:1-858)
130 140 150 160 170 180
pF1KA1 TDQVEAQGEKIRDLEFCLEEHREKLNATEEMLQQELLSRTSLETQKLDLMAEISNLKLKL
::::::::::::::::::::::::::::::
NP_001 MLQQELLSRTSLETQKLDLMAEISNLKLKL
10 20 30
190 200 210 220 230 240
pF1KA1 TAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKSLMAKLSSMKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKSLMAKLSSMKI
40 50 60 70 80 90
250 260 270 280 290 300
pF1KA1 KVGQMQYEKQRMEQKWESLKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVDRDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVGQMQYEKQRMEQKWESLKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVDRDI
100 110 120 130 140 150
310 320 330 340 350 360
pF1KA1 EVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGKDGEYEELLNSSSIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGKDGEYEELLNSSSIS
160 170 180 190 200 210
370 380 390 400 410 420
pF1KA1 SLLDAQGFSDLEKSPSPTPVMGSPSCDPFNTSVPEEFHTTILQVSIPSLLPATVSMETSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLLDAQGFSDLEKSPSPTPVMGSPSCDPFNTSVPEEFHTTILQVSIPSLLPATVSMETSE
220 230 240 250 260 270
430 440 450 460 470 480
pF1KA1 KSKLTPKPETSFEENDGNIILGATVDTQLCDKLLTSSLQKSSSLGNLKKETSDGEKETIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSKLTPKPETSFEENDGNIILGATVDTQLCDKLLTSSLQKSSSLGNLKKETSDGEKETIQ
280 290 300 310 320 330
490 500 510 520 530 540
pF1KA1 KTSEDRAPAESRPFGTLPPRPPGQDTSMDDNPFGTRKVRSSFGRGFFKIKSNKRTASAPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KTSEDRAPAESRPFGTLPPRPPGQDTSMDDNPFGTRKVRSSFGRGFFKIKSNKRTASAPN
340 350 360 370 380 390
550 560 570 580 590 600
pF1KA1 LAETEKETAEHLDLAGASSRPKDSQRNSPFQIPPPSPDSKKKSRGIMKLFGKLRRSQSTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAETEKETAEHLDLAGASSRPKDSQRNSPFQIPPPSPDSKKKSRGIMKLFGKLRRSQSTT
400 410 420 430 440 450
610 620 630 640 650 660
pF1KA1 FNPDDMSEPEFKRGGTRATAGPRLGWSRDLGQSNSDLDMPFAKWTKEQVCNWLMEQGLGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FNPDDMSEPEFKRGGTRATAGPRLGWSRDLGQSNSDLDMPFAKWTKEQVCNWLMEQGLGS
460 470 480 490 500 510
670 680 690 700 710 720
pF1KA1 YLNSGKHWIASGQTLLQASQQDLEKELGIKHSLHRKKLQLALQALGSEEETNHGKLDFNW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YLNSGKHWIASGQTLLQASQQDLEKELGIKHSLHRKKLQLALQALGSEEETNHGKLDFNW
520 530 540 550 560 570
730 740 750 760 770 780
pF1KA1 VTRWLDDIGLPQYKTQFDEGRVDGRMLHYMTVDDLLSLKVVSVLHHLSIKRAIQVLRINN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTRWLDDIGLPQYKTQFDEGRVDGRMLHYMTVDDLLSLKVVSVLHHLSIKRAIQVLRINN
580 590 600 610 620 630
790 800 810 820 830 840
pF1KA1 FEPNCLRRRPSDENTIAPSEVQKWTNHRVMEWLRSVDLAEYAPNLRGSGVHGGLMVLEPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FEPNCLRRRPSDENTIAPSEVQKWTNHRVMEWLRSVDLAEYAPNLRGSGVHGGLMVLEPR
640 650 660 670 680 690
850 860 870 880 890 900
pF1KA1 FNVETMAQLLNIPPNKTLLRRHLATHFNLLIGAEAQHQKRDAMELPDYVLLTATAKVKPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FNVETMAQLLNIPPNKTLLRRHLATHFNLLIGAEAQHQKRDAMELPDYVLLTATAKVKPK
700 710 720 730 740 750
910 920 930 940 950 960
pF1KA1 KLAFSNFGNLRKKKQEDGEEYVCPMELGQASGSASKKGFKPGLDMRLYEEDDLDRLEQME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLAFSNFGNLRKKKQEDGEEYVCPMELGQASGSASKKGFKPGLDMRLYEEDDLDRLEQME
760 770 780 790 800 810
970 980 990 1000 1010
pF1KA1 DSEGTVRQIGAFSEGINNLTHMLKEDDMFKDFAARSPSASITDEDSNV
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSEGTVRQIGAFSEGINNLTHMLKEDDMFKDFAARSPSASITDEDSNV
820 830 840 850
>>XP_016875563 (OMIM: 603141) PREDICTED: liprin-beta-1 i (861 aa)
initn: 4413 init1: 4413 opt: 5595 Z-score: 2842.0 bits: 537.2 E(85289): 1.5e-151
Smith-Waterman score: 5595; 99.7% identity (99.7% similar) in 861 aa overlap (154-1011:1-861)
130 140 150 160 170 180
pF1KA1 TDQVEAQGEKIRDLEFCLEEHREKLNATEEMLQQELLSRTSLETQKLDLMAEISNLKLKL
::::::::::::::::::::::::::::::
XP_016 MLQQELLSRTSLETQKLDLMAEISNLKLKL
10 20 30
190 200 210 220 230 240
pF1KA1 TAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKSLMAKLSSMKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKSLMAKLSSMKI
40 50 60 70 80 90
250 260 270 280 290 300
pF1KA1 KVGQMQYEKQRMEQKWESLKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVDRDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVGQMQYEKQRMEQKWESLKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVDRDI
100 110 120 130 140 150
310 320 330 340 350 360
pF1KA1 EVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGK---DGEYEELLNSS
:::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
XP_016 EVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGKKGKDGEYEELLNSS
160 170 180 190 200 210
370 380 390 400 410 420
pF1KA1 SISSLLDAQGFSDLEKSPSPTPVMGSPSCDPFNTSVPEEFHTTILQVSIPSLLPATVSME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SISSLLDAQGFSDLEKSPSPTPVMGSPSCDPFNTSVPEEFHTTILQVSIPSLLPATVSME
220 230 240 250 260 270
430 440 450 460 470 480
pF1KA1 TSEKSKLTPKPETSFEENDGNIILGATVDTQLCDKLLTSSLQKSSSLGNLKKETSDGEKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSEKSKLTPKPETSFEENDGNIILGATVDTQLCDKLLTSSLQKSSSLGNLKKETSDGEKE
280 290 300 310 320 330
490 500 510 520 530 540
pF1KA1 TIQKTSEDRAPAESRPFGTLPPRPPGQDTSMDDNPFGTRKVRSSFGRGFFKIKSNKRTAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TIQKTSEDRAPAESRPFGTLPPRPPGQDTSMDDNPFGTRKVRSSFGRGFFKIKSNKRTAS
340 350 360 370 380 390
550 560 570 580 590 600
pF1KA1 APNLAETEKETAEHLDLAGASSRPKDSQRNSPFQIPPPSPDSKKKSRGIMKLFGKLRRSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APNLAETEKETAEHLDLAGASSRPKDSQRNSPFQIPPPSPDSKKKSRGIMKLFGKLRRSQ
400 410 420 430 440 450
610 620 630 640 650 660
pF1KA1 STTFNPDDMSEPEFKRGGTRATAGPRLGWSRDLGQSNSDLDMPFAKWTKEQVCNWLMEQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STTFNPDDMSEPEFKRGGTRATAGPRLGWSRDLGQSNSDLDMPFAKWTKEQVCNWLMEQG
460 470 480 490 500 510
670 680 690 700 710 720
pF1KA1 LGSYLNSGKHWIASGQTLLQASQQDLEKELGIKHSLHRKKLQLALQALGSEEETNHGKLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGSYLNSGKHWIASGQTLLQASQQDLEKELGIKHSLHRKKLQLALQALGSEEETNHGKLD
520 530 540 550 560 570
730 740 750 760 770 780
pF1KA1 FNWVTRWLDDIGLPQYKTQFDEGRVDGRMLHYMTVDDLLSLKVVSVLHHLSIKRAIQVLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FNWVTRWLDDIGLPQYKTQFDEGRVDGRMLHYMTVDDLLSLKVVSVLHHLSIKRAIQVLR
580 590 600 610 620 630
790 800 810 820 830 840
pF1KA1 INNFEPNCLRRRPSDENTIAPSEVQKWTNHRVMEWLRSVDLAEYAPNLRGSGVHGGLMVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INNFEPNCLRRRPSDENTIAPSEVQKWTNHRVMEWLRSVDLAEYAPNLRGSGVHGGLMVL
640 650 660 670 680 690
850 860 870 880 890 900
pF1KA1 EPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLIGAEAQHQKRDAMELPDYVLLTATAKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLIGAEAQHQKRDAMELPDYVLLTATAKV
700 710 720 730 740 750
910 920 930 940 950 960
pF1KA1 KPKKLAFSNFGNLRKKKQEDGEEYVCPMELGQASGSASKKGFKPGLDMRLYEEDDLDRLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPKKLAFSNFGNLRKKKQEDGEEYVCPMELGQASGSASKKGFKPGLDMRLYEEDDLDRLE
760 770 780 790 800 810
970 980 990 1000 1010
pF1KA1 QMEDSEGTVRQIGAFSEGINNLTHMLKEDDMFKDFAARSPSASITDEDSNV
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QMEDSEGTVRQIGAFSEGINNLTHMLKEDDMFKDFAARSPSASITDEDSNV
820 830 840 850 860
>>NP_001185845 (OMIM: 603141) liprin-beta-1 isoform 4 [H (980 aa)
initn: 5089 init1: 5089 opt: 5104 Z-score: 2594.0 bits: 491.5 E(85289): 9.5e-138
Smith-Waterman score: 6336; 96.9% identity (96.9% similar) in 1011 aa overlap (1-1011:1-980)
10 20 30 40 50 60
pF1KA1 MMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGSLRALHLVEDLRGLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGSLRALHLVEDLRGLLE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 MMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARLENDKESLVLQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARLENDKESLVLQV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 SVLTDQVEAQGEKIRDLEFCLEEHREKLNATEEMLQQELLSRTSLETQKLDLMAEISNLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVLTDQVEAQGEKIRDLEFCLEEHREKLNATEEMLQQELLSRTSLETQKLDLMAEISNLK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKSLMAKLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTK--------
190 200 210 220 230
250 260 270 280 290 300
pF1KA1 MKIKVGQMQYEKQRMEQKWESLKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVD
:::::::::::::::::::::::::::::::::::::
NP_001 -----------------------DELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVD
240 250 260
310 320 330 340 350 360
pF1KA1 RDIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGKDGEYEELLNSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RDIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGKDGEYEELLNSS
270 280 290 300 310 320
370 380 390 400 410 420
pF1KA1 SISSLLDAQGFSDLEKSPSPTPVMGSPSCDPFNTSVPEEFHTTILQVSIPSLLPATVSME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SISSLLDAQGFSDLEKSPSPTPVMGSPSCDPFNTSVPEEFHTTILQVSIPSLLPATVSME
330 340 350 360 370 380
430 440 450 460 470 480
pF1KA1 TSEKSKLTPKPETSFEENDGNIILGATVDTQLCDKLLTSSLQKSSSLGNLKKETSDGEKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSEKSKLTPKPETSFEENDGNIILGATVDTQLCDKLLTSSLQKSSSLGNLKKETSDGEKE
390 400 410 420 430 440
490 500 510 520 530 540
pF1KA1 TIQKTSEDRAPAESRPFGTLPPRPPGQDTSMDDNPFGTRKVRSSFGRGFFKIKSNKRTAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIQKTSEDRAPAESRPFGTLPPRPPGQDTSMDDNPFGTRKVRSSFGRGFFKIKSNKRTAS
450 460 470 480 490 500
550 560 570 580 590 600
pF1KA1 APNLAETEKETAEHLDLAGASSRPKDSQRNSPFQIPPPSPDSKKKSRGIMKLFGKLRRSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APNLAETEKETAEHLDLAGASSRPKDSQRNSPFQIPPPSPDSKKKSRGIMKLFGKLRRSQ
510 520 530 540 550 560
610 620 630 640 650 660
pF1KA1 STTFNPDDMSEPEFKRGGTRATAGPRLGWSRDLGQSNSDLDMPFAKWTKEQVCNWLMEQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STTFNPDDMSEPEFKRGGTRATAGPRLGWSRDLGQSNSDLDMPFAKWTKEQVCNWLMEQG
570 580 590 600 610 620
670 680 690 700 710 720
pF1KA1 LGSYLNSGKHWIASGQTLLQASQQDLEKELGIKHSLHRKKLQLALQALGSEEETNHGKLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGSYLNSGKHWIASGQTLLQASQQDLEKELGIKHSLHRKKLQLALQALGSEEETNHGKLD
630 640 650 660 670 680
730 740 750 760 770 780
pF1KA1 FNWVTRWLDDIGLPQYKTQFDEGRVDGRMLHYMTVDDLLSLKVVSVLHHLSIKRAIQVLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FNWVTRWLDDIGLPQYKTQFDEGRVDGRMLHYMTVDDLLSLKVVSVLHHLSIKRAIQVLR
690 700 710 720 730 740
790 800 810 820 830 840
pF1KA1 INNFEPNCLRRRPSDENTIAPSEVQKWTNHRVMEWLRSVDLAEYAPNLRGSGVHGGLMVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 INNFEPNCLRRRPSDENTIAPSEVQKWTNHRVMEWLRSVDLAEYAPNLRGSGVHGGLMVL
750 760 770 780 790 800
850 860 870 880 890 900
pF1KA1 EPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLIGAEAQHQKRDAMELPDYVLLTATAKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLIGAEAQHQKRDAMELPDYVLLTATAKV
810 820 830 840 850 860
910 920 930 940 950 960
pF1KA1 KPKKLAFSNFGNLRKKKQEDGEEYVCPMELGQASGSASKKGFKPGLDMRLYEEDDLDRLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KPKKLAFSNFGNLRKKKQEDGEEYVCPMELGQASGSASKKGFKPGLDMRLYEEDDLDRLE
870 880 890 900 910 920
970 980 990 1000 1010
pF1KA1 QMEDSEGTVRQIGAFSEGINNLTHMLKEDDMFKDFAARSPSASITDEDSNV
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QMEDSEGTVRQIGAFSEGINNLTHMLKEDDMFKDFAARSPSASITDEDSNV
930 940 950 960 970 980
>>XP_016875561 (OMIM: 603141) PREDICTED: liprin-beta-1 i (983 aa)
initn: 5878 init1: 4413 opt: 5081 Z-score: 2582.4 bits: 489.3 E(85289): 4.2e-137
Smith-Waterman score: 6316; 96.5% identity (96.6% similar) in 1014 aa overlap (1-1011:1-983)
10 20 30 40 50 60
pF1KA1 MMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGSLRALHLVEDLRGLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGSLRALHLVEDLRGLLE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 MMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARLENDKESLVLQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARLENDKESLVLQV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 SVLTDQVEAQGEKIRDLEFCLEEHREKLNATEEMLQQELLSRTSLETQKLDLMAEISNLK
:::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::
XP_016 SVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQKLDLMAEISNLK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKSLMAKLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTK--------
190 200 210 220 230
250 260 270 280 290 300
pF1KA1 MKIKVGQMQYEKQRMEQKWESLKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVD
:::::::::::::::::::::::::::::::::::::
XP_016 -----------------------DELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVD
240 250 260
310 320 330 340 350
pF1KA1 RDIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGK---DGEYEELL
::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::
XP_016 RDIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGKKGKDGEYEELL
270 280 290 300 310 320
360 370 380 390 400 410
pF1KA1 NSSSISSLLDAQGFSDLEKSPSPTPVMGSPSCDPFNTSVPEEFHTTILQVSIPSLLPATV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSSSISSLLDAQGFSDLEKSPSPTPVMGSPSCDPFNTSVPEEFHTTILQVSIPSLLPATV
330 340 350 360 370 380
420 430 440 450 460 470
pF1KA1 SMETSEKSKLTPKPETSFEENDGNIILGATVDTQLCDKLLTSSLQKSSSLGNLKKETSDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SMETSEKSKLTPKPETSFEENDGNIILGATVDTQLCDKLLTSSLQKSSSLGNLKKETSDG
390 400 410 420 430 440
480 490 500 510 520 530
pF1KA1 EKETIQKTSEDRAPAESRPFGTLPPRPPGQDTSMDDNPFGTRKVRSSFGRGFFKIKSNKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKETIQKTSEDRAPAESRPFGTLPPRPPGQDTSMDDNPFGTRKVRSSFGRGFFKIKSNKR
450 460 470 480 490 500
540 550 560 570 580 590
pF1KA1 TASAPNLAETEKETAEHLDLAGASSRPKDSQRNSPFQIPPPSPDSKKKSRGIMKLFGKLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TASAPNLAETEKETAEHLDLAGASSRPKDSQRNSPFQIPPPSPDSKKKSRGIMKLFGKLR
510 520 530 540 550 560
600 610 620 630 640 650
pF1KA1 RSQSTTFNPDDMSEPEFKRGGTRATAGPRLGWSRDLGQSNSDLDMPFAKWTKEQVCNWLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSQSTTFNPDDMSEPEFKRGGTRATAGPRLGWSRDLGQSNSDLDMPFAKWTKEQVCNWLM
570 580 590 600 610 620
660 670 680 690 700 710
pF1KA1 EQGLGSYLNSGKHWIASGQTLLQASQQDLEKELGIKHSLHRKKLQLALQALGSEEETNHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQGLGSYLNSGKHWIASGQTLLQASQQDLEKELGIKHSLHRKKLQLALQALGSEEETNHG
630 640 650 660 670 680
720 730 740 750 760 770
pF1KA1 KLDFNWVTRWLDDIGLPQYKTQFDEGRVDGRMLHYMTVDDLLSLKVVSVLHHLSIKRAIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLDFNWVTRWLDDIGLPQYKTQFDEGRVDGRMLHYMTVDDLLSLKVVSVLHHLSIKRAIQ
690 700 710 720 730 740
780 790 800 810 820 830
pF1KA1 VLRINNFEPNCLRRRPSDENTIAPSEVQKWTNHRVMEWLRSVDLAEYAPNLRGSGVHGGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLRINNFEPNCLRRRPSDENTIAPSEVQKWTNHRVMEWLRSVDLAEYAPNLRGSGVHGGL
750 760 770 780 790 800
840 850 860 870 880 890
pF1KA1 MVLEPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLIGAEAQHQKRDAMELPDYVLLTAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVLEPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLIGAEAQHQKRDAMELPDYVLLTAT
810 820 830 840 850 860
900 910 920 930 940 950
pF1KA1 AKVKPKKLAFSNFGNLRKKKQEDGEEYVCPMELGQASGSASKKGFKPGLDMRLYEEDDLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKVKPKKLAFSNFGNLRKKKQEDGEEYVCPMELGQASGSASKKGFKPGLDMRLYEEDDLD
870 880 890 900 910 920
960 970 980 990 1000 1010
pF1KA1 RLEQMEDSEGTVRQIGAFSEGINNLTHMLKEDDMFKDFAARSPSASITDEDSNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLEQMEDSEGTVRQIGAFSEGINNLTHMLKEDDMFKDFAARSPSASITDEDSNV
930 940 950 960 970 980
>>XP_016875550 (OMIM: 603141) PREDICTED: liprin-beta-1 i (1022 aa)
initn: 4699 init1: 4699 opt: 4757 Z-score: 2418.9 bits: 459.1 E(85289): 5.4e-128
Smith-Waterman score: 6570; 98.8% identity (98.9% similar) in 1022 aa overlap (1-1011:1-1022)
10 20 30 40 50 60
pF1KA1 MMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGSLRALHLVEDLRGLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGSLRALHLVEDLRGLLE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 MMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARLENDKESLVLQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARLENDKESLVLQV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 SVLTDQVEAQGEKIRDLEFCLEEHREKLNATEEMLQQELLSRTSLETQKLDLMAEISNLK
:::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::
XP_016 SVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQKLDLMAEISNLK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKSLMAKLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKSLMAKLSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 MKIKVGQMQYEKQRMEQKWESLKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKIKVGQMQYEKQRMEQKWESLKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVD
250 260 270 280 290 300
310 320 330 340
pF1KA1 RD-----------IEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGK
:: :::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDENFKKKLKEKNIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGK
310 320 330 340 350 360
350 360 370 380 390 400
pF1KA1 DGEYEELLNSSSISSLLDAQGFSDLEKSPSPTPVMGSPSCDPFNTSVPEEFHTTILQVSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGEYEELLNSSSISSLLDAQGFSDLEKSPSPTPVMGSPSCDPFNTSVPEEFHTTILQVSI
370 380 390 400 410 420
410 420 430 440 450 460
pF1KA1 PSLLPATVSMETSEKSKLTPKPETSFEENDGNIILGATVDTQLCDKLLTSSLQKSSSLGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSLLPATVSMETSEKSKLTPKPETSFEENDGNIILGATVDTQLCDKLLTSSLQKSSSLGN
430 440 450 460 470 480
470 480 490 500 510 520
pF1KA1 LKKETSDGEKETIQKTSEDRAPAESRPFGTLPPRPPGQDTSMDDNPFGTRKVRSSFGRGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKKETSDGEKETIQKTSEDRAPAESRPFGTLPPRPPGQDTSMDDNPFGTRKVRSSFGRGF
490 500 510 520 530 540
530 540 550 560 570 580
pF1KA1 FKIKSNKRTASAPNLAETEKETAEHLDLAGASSRPKDSQRNSPFQIPPPSPDSKKKSRGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FKIKSNKRTASAPNLAETEKETAEHLDLAGASSRPKDSQRNSPFQIPPPSPDSKKKSRGI
550 560 570 580 590 600
590 600 610 620 630 640
pF1KA1 MKLFGKLRRSQSTTFNPDDMSEPEFKRGGTRATAGPRLGWSRDLGQSNSDLDMPFAKWTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKLFGKLRRSQSTTFNPDDMSEPEFKRGGTRATAGPRLGWSRDLGQSNSDLDMPFAKWTK
610 620 630 640 650 660
650 660 670 680 690 700
pF1KA1 EQVCNWLMEQGLGSYLNSGKHWIASGQTLLQASQQDLEKELGIKHSLHRKKLQLALQALG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQVCNWLMEQGLGSYLNSGKHWIASGQTLLQASQQDLEKELGIKHSLHRKKLQLALQALG
670 680 690 700 710 720
710 720 730 740 750 760
pF1KA1 SEEETNHGKLDFNWVTRWLDDIGLPQYKTQFDEGRVDGRMLHYMTVDDLLSLKVVSVLHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEEETNHGKLDFNWVTRWLDDIGLPQYKTQFDEGRVDGRMLHYMTVDDLLSLKVVSVLHH
730 740 750 760 770 780
770 780 790 800 810 820
pF1KA1 LSIKRAIQVLRINNFEPNCLRRRPSDENTIAPSEVQKWTNHRVMEWLRSVDLAEYAPNLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSIKRAIQVLRINNFEPNCLRRRPSDENTIAPSEVQKWTNHRVMEWLRSVDLAEYAPNLR
790 800 810 820 830 840
830 840 850 860 870 880
pF1KA1 GSGVHGGLMVLEPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLIGAEAQHQKRDAMELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSGVHGGLMVLEPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLIGAEAQHQKRDAMELP
850 860 870 880 890 900
890 900 910 920 930 940
pF1KA1 DYVLLTATAKVKPKKLAFSNFGNLRKKKQEDGEEYVCPMELGQASGSASKKGFKPGLDMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DYVLLTATAKVKPKKLAFSNFGNLRKKKQEDGEEYVCPMELGQASGSASKKGFKPGLDMR
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KA1 LYEEDDLDRLEQMEDSEGTVRQIGAFSEGINNLTHMLKEDDMFKDFAARSPSASITDEDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYEEDDLDRLEQMEDSEGTVRQIGAFSEGINNLTHMLKEDDMFKDFAARSPSASITDEDS
970 980 990 1000 1010 1020
1010
pF1KA1 NV
::
XP_016 NV
>>XP_016875559 (OMIM: 603141) PREDICTED: liprin-beta-1 i (991 aa)
initn: 6164 init1: 4699 opt: 4742 Z-score: 2411.6 bits: 457.7 E(85289): 1.4e-127
Smith-Waterman score: 6300; 95.8% identity (95.9% similar) in 1022 aa overlap (1-1011:1-991)
10 20 30 40 50 60
pF1KA1 MMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGSLRALHLVEDLRGLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGSLRALHLVEDLRGLLE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 MMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARLENDKESLVLQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARLENDKESLVLQV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 SVLTDQVEAQGEKIRDLEFCLEEHREKLNATEEMLQQELLSRTSLETQKLDLMAEISNLK
:::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::
XP_016 SVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQKLDLMAEISNLK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKSLMAKLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTK--------
190 200 210 220 230
250 260 270 280 290 300
pF1KA1 MKIKVGQMQYEKQRMEQKWESLKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVD
:::::::::::::::::::::::::::::::::::::
XP_016 -----------------------DELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVD
240 250 260
310 320 330 340
pF1KA1 RD-----------IEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGK
:: :::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDENFKKKLKEKNIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGK
270 280 290 300 310 320
350 360 370 380 390 400
pF1KA1 DGEYEELLNSSSISSLLDAQGFSDLEKSPSPTPVMGSPSCDPFNTSVPEEFHTTILQVSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGEYEELLNSSSISSLLDAQGFSDLEKSPSPTPVMGSPSCDPFNTSVPEEFHTTILQVSI
330 340 350 360 370 380
410 420 430 440 450 460
pF1KA1 PSLLPATVSMETSEKSKLTPKPETSFEENDGNIILGATVDTQLCDKLLTSSLQKSSSLGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSLLPATVSMETSEKSKLTPKPETSFEENDGNIILGATVDTQLCDKLLTSSLQKSSSLGN
390 400 410 420 430 440
470 480 490 500 510 520
pF1KA1 LKKETSDGEKETIQKTSEDRAPAESRPFGTLPPRPPGQDTSMDDNPFGTRKVRSSFGRGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKKETSDGEKETIQKTSEDRAPAESRPFGTLPPRPPGQDTSMDDNPFGTRKVRSSFGRGF
450 460 470 480 490 500
530 540 550 560 570 580
pF1KA1 FKIKSNKRTASAPNLAETEKETAEHLDLAGASSRPKDSQRNSPFQIPPPSPDSKKKSRGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FKIKSNKRTASAPNLAETEKETAEHLDLAGASSRPKDSQRNSPFQIPPPSPDSKKKSRGI
510 520 530 540 550 560
590 600 610 620 630 640
pF1KA1 MKLFGKLRRSQSTTFNPDDMSEPEFKRGGTRATAGPRLGWSRDLGQSNSDLDMPFAKWTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKLFGKLRRSQSTTFNPDDMSEPEFKRGGTRATAGPRLGWSRDLGQSNSDLDMPFAKWTK
570 580 590 600 610 620
650 660 670 680 690 700
pF1KA1 EQVCNWLMEQGLGSYLNSGKHWIASGQTLLQASQQDLEKELGIKHSLHRKKLQLALQALG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQVCNWLMEQGLGSYLNSGKHWIASGQTLLQASQQDLEKELGIKHSLHRKKLQLALQALG
630 640 650 660 670 680
710 720 730 740 750 760
pF1KA1 SEEETNHGKLDFNWVTRWLDDIGLPQYKTQFDEGRVDGRMLHYMTVDDLLSLKVVSVLHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEEETNHGKLDFNWVTRWLDDIGLPQYKTQFDEGRVDGRMLHYMTVDDLLSLKVVSVLHH
690 700 710 720 730 740
770 780 790 800 810 820
pF1KA1 LSIKRAIQVLRINNFEPNCLRRRPSDENTIAPSEVQKWTNHRVMEWLRSVDLAEYAPNLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSIKRAIQVLRINNFEPNCLRRRPSDENTIAPSEVQKWTNHRVMEWLRSVDLAEYAPNLR
750 760 770 780 790 800
830 840 850 860 870 880
pF1KA1 GSGVHGGLMVLEPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLIGAEAQHQKRDAMELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSGVHGGLMVLEPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLIGAEAQHQKRDAMELP
810 820 830 840 850 860
890 900 910 920 930 940
pF1KA1 DYVLLTATAKVKPKKLAFSNFGNLRKKKQEDGEEYVCPMELGQASGSASKKGFKPGLDMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DYVLLTATAKVKPKKLAFSNFGNLRKKKQEDGEEYVCPMELGQASGSASKKGFKPGLDMR
870 880 890 900 910 920
950 960 970 980 990 1000
pF1KA1 LYEEDDLDRLEQMEDSEGTVRQIGAFSEGINNLTHMLKEDDMFKDFAARSPSASITDEDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYEEDDLDRLEQMEDSEGTVRQIGAFSEGINNLTHMLKEDDMFKDFAARSPSASITDEDS
930 940 950 960 970 980
1010
pF1KA1 NV
::
XP_016 NV
990
1011 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 20:48:43 2016 done: Wed Nov 2 20:48:45 2016
Total Scan time: 13.450 Total Display time: 0.340
Function used was FASTA [36.3.4 Apr, 2011]