FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1237, 1482 aa 1>>>pF1KA1237 1482 - 1482 aa - 1482 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 12.2369+/-0.00124; mu= -7.3034+/- 0.075 mean_var=369.4396+/-74.720, 0's: 0 Z-trim(113.3): 87 B-trim: 40 in 1/49 Lambda= 0.066727 statistics sampled from 13843 (13921) to 13843 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.716), E-opt: 0.2 (0.428), width: 16 Scan time: 4.910 The best scores are: opt bits E(32554) CCDS46898.1 HEG1 gene_id:57493|Hs108|chr3 (1381) 5587 553.1 2.2e-156 >>CCDS46898.1 HEG1 gene_id:57493|Hs108|chr3 (1381 aa) initn: 8862 init1: 5561 opt: 5587 Z-score: 2921.1 bits: 553.1 E(32554): 2.2e-156 Smith-Waterman score: 8759; 93.0% identity (93.1% similar) in 1482 aa overlap (1-1482:1-1381) 10 20 30 40 50 60 pF1KA1 MASPRASRWPPPLLLLLLPLLLLMPPAAPGTRDPPPSPARRALSLAPLAGAGLELQLERR ::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::: CCDS46 MASPRASRWPPPLLLLLLPLLLL-PPAAPGTRDPPPSPARRALSLAPLAGAGLELQLERR 10 20 30 40 50 70 80 90 100 110 120 pF1KA1 PEREPPPTPPRERRGPATPGPSYRAPEPGAATQRGPSGRAPRGGSADAAWKHWPESNTEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 PEREPPPTPPRERRGPATPGPSYRAPEPGAATQRGPSGRAPRGGSADAAWKHWPESNTEA 60 70 80 90 100 110 130 140 150 160 170 180 pF1KA1 HVENITFYQNQEDFSTVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRSGSSSRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 HVENITFYQNQEDFSTVSSKEGVMVQTSGKSHAASDAPENLTLLAETADARGRSGSSSRT 120 130 140 150 160 170 190 200 210 220 230 240 pF1KA1 NFTILPVGYSLEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 NFTILPVGYSLEIATALTSQSGNLASESLHLPSSSSEFDERIAAFQTKSGTASEMGTERA 180 190 200 210 220 230 250 260 270 280 290 300 pF1KA1 MGLSEEWIVHSQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPL ::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 MGLSEEWTVHSQEATTSAWSPSFLPALEMGELTTPSRKRNSSGPDLSWLHFYRTAASSPL 240 250 260 270 280 290 310 320 330 340 350 360 pF1KA1 LDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 LDLSSSSESTEKLNNSTGLQSSSVSQTKTMHVATVFTDGGPRTLRSLTVSLGPVSKTEGF 300 310 320 330 340 350 370 380 390 400 410 420 pF1KA1 PKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 PKDSRIATTSSSVLLSPSAVESRRNSRVTGNPGDEEFIEPSTENEFGLTSLRWQNDSPTF 360 370 380 390 400 410 430 440 450 460 470 480 pF1KA1 GEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 GEHQLASSSEVQNGSPMSQTETVSRSVAPMRGGEITAHWLLTNSTTSADVTGSSASYPEG 420 430 440 450 460 470 490 500 510 520 530 540 pF1KA1 VNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGERSTLEDSREPGQ :::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 VNASVLTQFSDSTVQSGGSHTALGDRSYSESSSTSSSESLNSSAPRGERS---------- 480 490 500 510 520 550 560 570 580 590 600 pF1KA1 ALGDSSANAEDRTSGVPSLGTHTLATVTGNGERTLRSVTLTNTSMSTTSGEAGSPAAAMH CCDS46 ------------------------------------------------------------ 610 620 630 640 650 660 pF1KA1 QETEGASLHVNVTDDMGLVSRSLAASSALGVAGISYGQVRGTAIEQRTSSDHTDHTYLSS .::::::::::::::::::::::::::::: CCDS46 ------------------------------IAGISYGQVRGTAIEQRTSSDHTDHTYLSS 530 540 550 670 680 690 700 710 720 pF1KA1 TFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 TFTKGERALLSITDNSSSSDIVESSTSYIKISNSSHSEYSSFFHAQTERSNISSYDGEYA 560 570 580 590 600 610 730 740 750 760 770 780 pF1KA1 QPSTESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 QPSTESPVLHTSNLPSYTPTINMPNTSVVLDTDAEFVSDSSSSSSSSSSSSSSGPPLPLP 620 630 640 650 660 670 790 800 810 820 830 840 pF1KA1 SVSQSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 SVSQSHHLFSSILPSTRASVHLLKSTSDASTPWSSSPSPLPVSLTTSTSAPLSVSQTTLP 680 690 700 710 720 730 850 860 870 880 890 900 pF1KA1 QSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 QSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTADLKSQSTPHQEKVITESKSPSLV 740 750 760 770 780 790 910 920 930 940 950 960 pF1KA1 SLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 SLPTESTKAVTTNSPLPPSLTESSTEQTLPATSTNLAQMSPTFTTTILKTSQPLMTTPGT 800 810 820 830 840 850 970 980 990 1000 1010 1020 pF1KA1 LSSTASLVTGPIAVQTTAGKQLSLTHPEILVPQISTEGGISTERNRVIVDATTGLIPLTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 LSSTASLVTGPIAVQTTAGKQLSLTHPEILVPQISTEGGISTERNRVIVDATTGLIPLTS 860 870 880 890 900 910 1030 1040 1050 1060 1070 1080 pF1KA1 VPTSAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 VPTSAKEMTTKLGVTAEYSPASRSLGTSPSPQTTVVSTAEDLAPKSATFAVQSSTQSPTT 920 930 940 950 960 970 1090 1100 1110 1120 1130 1140 pF1KA1 VSSSASVNSCAVNPCLHNGECVADNTSRGYHCRCPPSWQGDDCSVDVNECLSNPCPSTAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 VSSSASVNSCAVNPCLHNGECVADNTSRGYHCRCPPSWQGDDCSVDVNECLSNPCPSTAM 980 990 1000 1010 1020 1030 1150 1160 1170 1180 1190 1200 pF1KA1 CNNTQGSFICKCPVGYQLEKGICNLVRTFVTEFKLKRTFLNTTVEKHSDLQEVENEITKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 CNNTQGSFICKCPVGYQLEKGICNLVRTFVTEFKLKRTFLNTTVEKHSDLQEVENEITKT 1040 1050 1060 1070 1080 1090 1210 1220 1230 1240 1250 1260 pF1KA1 LNMCFSALPSYIRSTVHASRESNAVVISLQTTFSLASNVTLFDLADRMQKCVNSCKSSAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 LNMCFSALPSYIRSTVHASRESNAVVISLQTTFSLASNVTLFDLADRMQKCVNSCKSSAE 1100 1110 1120 1130 1140 1150 1270 1280 1290 1300 1310 1320 pF1KA1 VCQLLGSQRRIFRAGSLCKRKSPECDKDTSICTDLDGVALCQCKSGYFQFNKMDHSCRAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 VCQLLGSQRRIFRAGSLCKRKSPECDKDTSICTDLDGVALCQCKSGYFQFNKMDHSCRAC 1160 1170 1180 1190 1200 1210 1330 1340 1350 1360 1370 1380 pF1KA1 EDGYRLENETCMSCPFGLGGLNCGNPYQLITVVIAAAGGGLLLILGIALIVTCCRKNKND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 EDGYRLENETCMSCPFGLGGLNCGNPYQLITVVIAAAGGGLLLILGIALIVTCCRKNKND 1220 1230 1240 1250 1260 1270 1390 1400 1410 1420 1430 1440 pF1KA1 ISKLIFKSGDFQMSPYAEYPKNPRSQEWGREAIEMHENGSTKNLLQMTDVYYSPTSVRNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 ISKLIFKSGDFQMSPYAEYPKNPRSQEWGREAIEMHENGSTKNLLQMTDVYYSPTSVRNP 1280 1290 1300 1310 1320 1330 1450 1460 1470 1480 pF1KA1 ELERNGLYPAYTGLPGSRHSCIFPGQYNPSFISDESRRRDYF :::::::::::::::::::::::::::::::::::::::::: CCDS46 ELERNGLYPAYTGLPGSRHSCIFPGQYNPSFISDESRRRDYF 1340 1350 1360 1370 1380 1482 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 20:49:24 2016 done: Wed Nov 2 20:49:25 2016 Total Scan time: 4.910 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]