FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1248, 357 aa 1>>>pF1KA1248 357 - 357 aa - 357 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.6429+/-0.000794; mu= 14.5925+/- 0.048 mean_var=65.9465+/-13.089, 0's: 0 Z-trim(108.3): 19 B-trim: 578 in 1/52 Lambda= 0.157935 statistics sampled from 10090 (10108) to 10090 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.7), E-opt: 0.2 (0.31), width: 16 Scan time: 1.920 The best scores are: opt bits E(32554) CCDS9564.1 NDRG2 gene_id:57447|Hs108|chr14 ( 357) 2394 554.1 6.7e-158 CCDS61386.1 NDRG2 gene_id:57447|Hs108|chr14 ( 367) 2394 554.1 6.8e-158 CCDS9565.1 NDRG2 gene_id:57447|Hs108|chr14 ( 371) 2239 518.8 3e-147 CCDS73613.1 NDRG2 gene_id:57447|Hs108|chr14 ( 341) 1749 407.1 1.1e-113 CCDS61384.1 NDRG2 gene_id:57447|Hs108|chr14 ( 360) 1516 354.0 1.1e-97 CCDS10797.1 NDRG4 gene_id:65009|Hs108|chr16 ( 371) 1497 349.7 2.3e-96 CCDS45500.1 NDRG4 gene_id:65009|Hs108|chr16 ( 391) 1497 349.7 2.4e-96 CCDS55999.1 NDRG4 gene_id:65009|Hs108|chr16 ( 369) 1496 349.5 2.7e-96 CCDS58465.1 NDRG4 gene_id:65009|Hs108|chr16 ( 357) 1493 348.8 4.2e-96 CCDS58467.1 NDRG4 gene_id:65009|Hs108|chr16 ( 339) 1492 348.5 4.7e-96 CCDS13284.1 NDRG3 gene_id:57446|Hs108|chr20 ( 363) 1357 317.8 9.1e-87 CCDS13285.1 NDRG3 gene_id:57446|Hs108|chr20 ( 375) 1349 316.0 3.3e-86 CCDS58466.1 NDRG4 gene_id:65009|Hs108|chr16 ( 352) 1346 315.3 5e-86 CCDS34945.1 NDRG1 gene_id:10397|Hs108|chr8 ( 394) 1339 313.7 1.7e-85 CCDS59113.1 NDRG1 gene_id:10397|Hs108|chr8 ( 328) 1183 278.1 7.2e-75 CCDS59112.1 NDRG1 gene_id:10397|Hs108|chr8 ( 313) 1105 260.4 1.5e-69 >>CCDS9564.1 NDRG2 gene_id:57447|Hs108|chr14 (357 aa) initn: 2394 init1: 2394 opt: 2394 Z-score: 2948.3 bits: 554.1 E(32554): 6.7e-158 Smith-Waterman score: 2394; 100.0% identity (100.0% similar) in 357 aa overlap (1-357:1-357) 10 20 30 40 50 60 pF1KA1 MAELQEVQITEEKPLLPGQTPEAAKTHSVETPYGSVTFTVYGTPKPKRPAILTYHDVGLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS95 MAELQEVQITEEKPLLPGQTPEAAKTHSVETPYGSVTFTVYGTPKPKRPAILTYHDVGLN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 YKSCFQPLFQFEDMQEIIQNFVRVHVDAPGMEEGAPVFPLGYQYPSLDQLADMIPCVLQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS95 YKSCFQPLFQFEDMQEIIQNFVRVHVDAPGMEEGAPVFPLGYQYPSLDQLADMIPCVLQY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 LNFSTIIGVGVGAGAYILARYALNHPDTVEGLVLINIDPNAKGWMDWAAHKLTGLTSSIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS95 LNFSTIIGVGVGAGAYILARYALNHPDTVEGLVLINIDPNAKGWMDWAAHKLTGLTSSIP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 EMILGHLFSQEELSGNSELIQKYRNIITHAPNLDNIELYWNSYNNRRDLNFERGGDITLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS95 EMILGHLFSQEELSGNSELIQKYRNIITHAPNLDNIELYWNSYNNRRDLNFERGGDITLR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 CPVMLVVGDQAPHEDAVVECNSKLDPTQTSFLKMADSGGQPQLTQPGKLTEAFKYFLQGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS95 CPVMLVVGDQAPHEDAVVECNSKLDPTQTSFLKMADSGGQPQLTQPGKLTEAFKYFLQGM 250 260 270 280 290 300 310 320 330 340 350 pF1KA1 GYMASSCMTRLSRSRTASLTSAASVDGNRSRSRTLSQSSESGTLSSGPPGHTMEVSC ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS95 GYMASSCMTRLSRSRTASLTSAASVDGNRSRSRTLSQSSESGTLSSGPPGHTMEVSC 310 320 330 340 350 >>CCDS61386.1 NDRG2 gene_id:57447|Hs108|chr14 (367 aa) initn: 2394 init1: 2394 opt: 2394 Z-score: 2948.1 bits: 554.1 E(32554): 6.8e-158 Smith-Waterman score: 2394; 100.0% identity (100.0% similar) in 357 aa overlap (1-357:11-367) 10 20 30 40 50 pF1KA1 MAELQEVQITEEKPLLPGQTPEAAKTHSVETPYGSVTFTVYGTPKPKRPA :::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 MENGGSMQATMAELQEVQITEEKPLLPGQTPEAAKTHSVETPYGSVTFTVYGTPKPKRPA 10 20 30 40 50 60 60 70 80 90 100 110 pF1KA1 ILTYHDVGLNYKSCFQPLFQFEDMQEIIQNFVRVHVDAPGMEEGAPVFPLGYQYPSLDQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 ILTYHDVGLNYKSCFQPLFQFEDMQEIIQNFVRVHVDAPGMEEGAPVFPLGYQYPSLDQL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KA1 ADMIPCVLQYLNFSTIIGVGVGAGAYILARYALNHPDTVEGLVLINIDPNAKGWMDWAAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 ADMIPCVLQYLNFSTIIGVGVGAGAYILARYALNHPDTVEGLVLINIDPNAKGWMDWAAH 130 140 150 160 170 180 180 190 200 210 220 230 pF1KA1 KLTGLTSSIPEMILGHLFSQEELSGNSELIQKYRNIITHAPNLDNIELYWNSYNNRRDLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 KLTGLTSSIPEMILGHLFSQEELSGNSELIQKYRNIITHAPNLDNIELYWNSYNNRRDLN 190 200 210 220 230 240 240 250 260 270 280 290 pF1KA1 FERGGDITLRCPVMLVVGDQAPHEDAVVECNSKLDPTQTSFLKMADSGGQPQLTQPGKLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 FERGGDITLRCPVMLVVGDQAPHEDAVVECNSKLDPTQTSFLKMADSGGQPQLTQPGKLT 250 260 270 280 290 300 300 310 320 330 340 350 pF1KA1 EAFKYFLQGMGYMASSCMTRLSRSRTASLTSAASVDGNRSRSRTLSQSSESGTLSSGPPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 EAFKYFLQGMGYMASSCMTRLSRSRTASLTSAASVDGNRSRSRTLSQSSESGTLSSGPPG 310 320 330 340 350 360 pF1KA1 HTMEVSC ::::::: CCDS61 HTMEVSC >>CCDS9565.1 NDRG2 gene_id:57447|Hs108|chr14 (371 aa) initn: 2239 init1: 2239 opt: 2239 Z-score: 2757.2 bits: 518.8 E(32554): 3e-147 Smith-Waterman score: 2356; 96.2% identity (96.2% similar) in 371 aa overlap (1-357:1-371) 10 20 30 40 pF1KA1 MAELQEVQITEEKPLLPGQTPEAAK--------------THSVETPYGSVTFTVYGTPKP ::::::::::::::::::::::::: ::::::::::::::::::::: CCDS95 MAELQEVQITEEKPLLPGQTPEAAKEAELAARILLDQGQTHSVETPYGSVTFTVYGTPKP 10 20 30 40 50 60 50 60 70 80 90 100 pF1KA1 KRPAILTYHDVGLNYKSCFQPLFQFEDMQEIIQNFVRVHVDAPGMEEGAPVFPLGYQYPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS95 KRPAILTYHDVGLNYKSCFQPLFQFEDMQEIIQNFVRVHVDAPGMEEGAPVFPLGYQYPS 70 80 90 100 110 120 110 120 130 140 150 160 pF1KA1 LDQLADMIPCVLQYLNFSTIIGVGVGAGAYILARYALNHPDTVEGLVLINIDPNAKGWMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS95 LDQLADMIPCVLQYLNFSTIIGVGVGAGAYILARYALNHPDTVEGLVLINIDPNAKGWMD 130 140 150 160 170 180 170 180 190 200 210 220 pF1KA1 WAAHKLTGLTSSIPEMILGHLFSQEELSGNSELIQKYRNIITHAPNLDNIELYWNSYNNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS95 WAAHKLTGLTSSIPEMILGHLFSQEELSGNSELIQKYRNIITHAPNLDNIELYWNSYNNR 190 200 210 220 230 240 230 240 250 260 270 280 pF1KA1 RDLNFERGGDITLRCPVMLVVGDQAPHEDAVVECNSKLDPTQTSFLKMADSGGQPQLTQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS95 RDLNFERGGDITLRCPVMLVVGDQAPHEDAVVECNSKLDPTQTSFLKMADSGGQPQLTQP 250 260 270 280 290 300 290 300 310 320 330 340 pF1KA1 GKLTEAFKYFLQGMGYMASSCMTRLSRSRTASLTSAASVDGNRSRSRTLSQSSESGTLSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS95 GKLTEAFKYFLQGMGYMASSCMTRLSRSRTASLTSAASVDGNRSRSRTLSQSSESGTLSS 310 320 330 340 350 360 350 pF1KA1 GPPGHTMEVSC ::::::::::: CCDS95 GPPGHTMEVSC 370 >>CCDS73613.1 NDRG2 gene_id:57447|Hs108|chr14 (341 aa) initn: 1767 init1: 1744 opt: 1749 Z-score: 2154.4 bits: 407.1 E(32554): 1.1e-113 Smith-Waterman score: 2246; 95.5% identity (95.5% similar) in 357 aa overlap (1-357:1-341) 10 20 30 40 50 60 pF1KA1 MAELQEVQITEEKPLLPGQTPEAAKTHSVETPYGSVTFTVYGTPKPKRPAILTYHDVGLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 MAELQEVQITEEKPLLPGQTPEAAKTHSVETPYGSVTFTVYGTPKPKRPAILTYHDVGLN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 YKSCFQPLFQFEDMQEIIQNFVRVHVDAPGMEEGAPVFPLGYQYPSLDQLADMIPCVLQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 YKSCFQPLFQFEDMQEIIQNFVRVHVDAPGMEEGAPVFPLGYQYPSLDQLADMIPCVLQY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 LNFSTIIGVGVGAGAYILARYALNHPDTVEGLVLINIDPNAKGWMDWAAHKLTGLTSSIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 LNFSTIIGVGVGAGAYILARYALNHPDTVEGLVLINIDPNAKGWMDWAAHKLTGLTSSIP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 EMILGHLFSQEELSGNSELIQKYRNIITHAPNLDNIELYWNSYNNRRDLNFERGGDITLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 EMILGHLFSQEELSGNSELIQKYRNIITHAPNLDNIELYWNSYNNRRDLNFERGGDITLR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 CPVMLVVGDQAPHEDAVVECNSKLDPTQTSFLKMADSGGQPQLTQPGKLTEAFKYFLQGM ::::::::::::::::: ::::::::::::::::::::::::::: CCDS73 CPVMLVVGDQAPHEDAV----------------MADSGGQPQLTQPGKLTEAFKYFLQGM 250 260 270 280 310 320 330 340 350 pF1KA1 GYMASSCMTRLSRSRTASLTSAASVDGNRSRSRTLSQSSESGTLSSGPPGHTMEVSC ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 GYMASSCMTRLSRSRTASLTSAASVDGNRSRSRTLSQSSESGTLSSGPPGHTMEVSC 290 300 310 320 330 340 >>CCDS61384.1 NDRG2 gene_id:57447|Hs108|chr14 (360 aa) initn: 1539 init1: 1516 opt: 1516 Z-score: 1867.1 bits: 354.0 E(32554): 1.1e-97 Smith-Waterman score: 2247; 93.3% identity (93.3% similar) in 371 aa overlap (1-357:1-360) 10 20 30 40 pF1KA1 MAELQEVQITEEKPLLPGQTPEAAK--------------THSVETPYGSVTFTVYGTPKP ::::::::::::::::::::::::: ::::::::::::::::::::: CCDS61 MAELQEVQITEEKPLLPGQTPEAAKEAELAARILLDQGQTHSVETPYGSVTFTVYGTPKP 10 20 30 40 50 60 50 60 70 80 90 100 pF1KA1 KRPAILTYHDVGLNYKSCFQPLFQFEDMQEIIQNFVRVHVDAPGMEEGAPVFPLGYQYPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 KRPAILTYHDVGLNYKSCFQPLFQFEDMQEIIQNFVRVHVDAPGMEEGAPVFPLGYQYPS 70 80 90 100 110 120 110 120 130 140 150 160 pF1KA1 LDQLADMIPCVLQYLNFSTIIGVGVGAGAYILARYALNHPDTVEGLVLINIDPNAKGWMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 LDQLADMIPCVLQYLNFSTIIGVGVGAGAYILARYALNHPDTVEGLVLINIDPNAKGWMD 130 140 150 160 170 180 170 180 190 200 210 220 pF1KA1 WAAHKLTGLTSSIPEMILGHLFSQEELSGNSELIQKYRNIITHAPNLDNIELYWNSYNNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 WAAHKLTGLTSSIPEMILGHLFSQEELSGNSELIQKYRNIITHAPNLDNIELYWNSYNNR 190 200 210 220 230 240 230 240 250 260 270 280 pF1KA1 RDLNFERGGDITLRCPVMLVVGDQAPHEDAVVECNSKLDPTQTSFLKMADSGGQPQLTQP ::::::::::::::::::::: :::::::::::::::::::::::::::: CCDS61 RDLNFERGGDITLRCPVMLVV-----------ECNSKLDPTQTSFLKMADSGGQPQLTQP 250 260 270 280 290 300 310 320 330 340 pF1KA1 GKLTEAFKYFLQGMGYMASSCMTRLSRSRTASLTSAASVDGNRSRSRTLSQSSESGTLSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS61 GKLTEAFKYFLQGMGYMASSCMTRLSRSRTASLTSAASVDGNRSRSRTLSQSSESGTLSS 290 300 310 320 330 340 350 pF1KA1 GPPGHTMEVSC ::::::::::: CCDS61 GPPGHTMEVSC 350 360 >>CCDS10797.1 NDRG4 gene_id:65009|Hs108|chr16 (371 aa) initn: 1531 init1: 937 opt: 1497 Z-score: 1843.5 bits: 349.7 E(32554): 2.3e-96 Smith-Waterman score: 1534; 62.7% identity (81.1% similar) in 375 aa overlap (1-357:1-371) 10 20 30 40 pF1KA1 MAELQEVQITEEKPLLPGQTPE----------AA----KTHSVETPYGSVTFTVYGTPKP :: :::... :::::: :: :: : :..::::: . .. :.:: CCDS10 MAGLQELRFPEEKPLLRGQDATELESSDAFLLAADTDWKEHDIETPYGLLHVVIRGSPKG 10 20 30 40 50 60 50 60 70 80 90 100 pF1KA1 KRPAILTYHDVGLNYKSCFQPLFQFEDMQEIIQNFVRVHVDAPGMEEGAPVFPLGYQYPS .:::::::::::::.: ::. .:.::::::: ..:: ::::::.. :: :: :::.:: CCDS10 NRPAILTYHDVGLNHKLCFNTFFNFEDMQEITKHFVVCHVDAPGQQVGASQFPQGYQFPS 70 80 90 100 110 120 110 120 130 140 150 160 pF1KA1 LDQLADMIPCVLQYLNFSTIIGVGVGAGAYILARYALNHPDTVEGLVLINIDPNAKGWMD ..::: :.: :.:...:. .::.:::::::.::..:: :: ::::::.:::::.:::.: CCDS10 MEQLAAMLPSVVQHFGFKYVIGIGVGAGAYVLAKFALIFPDLVEGLVLVNIDPNGKGWID 130 140 150 160 170 180 170 180 190 200 210 220 pF1KA1 WAAHKLTGLTSSIPEMILGHLFSQEELSGNSELIQKYRNIITHAPNLDNIELYWNSYNNR ::: ::.::::..:. .:.:::::::: .:.::.:.::. : .. : :..:.:: ::.: CCDS10 WAATKLSGLTSTLPDTVLSHLFSQEELVNNTELVQSYRQQIGNVVNQANLQLFWNMYNSR 190 200 210 220 230 240 230 240 250 260 270 280 pF1KA1 RDLNFERGGDI----TLRCPVMLVVGDQAPHEDAVVECNSKLDPTQTSFLKMADSGGQPQ :::...: : . ::::::::::::.:: ::.::::::::::: :.::::::::: :: CCDS10 RDLDINRPGTVPNAKTLRCPVMLVVGDNAPAEDGVVECNSKLDPTTTTFLKMADSGGLPQ 250 260 270 280 290 300 290 300 310 320 330 340 pF1KA1 LTQPGKLTEAFKYFLQGMGYMASSCMTRLSRSRTASLTSAASVDGNRSRSRTLSQSSESG .:::::::::::::::::::: :. ::::.::::::::::.::::.: .. : :.:::. CCDS10 VTQPGKLTEAFKYFLQGMGYMPSASMTRLARSRTASLTSASSVDGSRPQACTHSESSEG- 310 320 330 340 350 350 pF1KA1 TLSSGPPGHTMEVSC : .::::::: CCDS10 ---LGQVNHTMEVSC 360 370 >>CCDS45500.1 NDRG4 gene_id:65009|Hs108|chr16 (391 aa) initn: 1531 init1: 937 opt: 1497 Z-score: 1843.1 bits: 349.7 E(32554): 2.4e-96 Smith-Waterman score: 1534; 62.7% identity (81.1% similar) in 375 aa overlap (1-357:21-391) 10 20 pF1KA1 MAELQEVQITEEKPLLPGQTPE----------AA----KT :: :::... :::::: :: :: : CCDS45 MKVLGHRLELLTGLLLHDVTMAGLQELRFPEEKPLLRGQDATELESSDAFLLAADTDWKE 10 20 30 40 50 60 30 40 50 60 70 80 pF1KA1 HSVETPYGSVTFTVYGTPKPKRPAILTYHDVGLNYKSCFQPLFQFEDMQEIIQNFVRVHV :..::::: . .. :.:: .:::::::::::::.: ::. .:.::::::: ..:: :: CCDS45 HDIETPYGLLHVVIRGSPKGNRPAILTYHDVGLNHKLCFNTFFNFEDMQEITKHFVVCHV 70 80 90 100 110 120 90 100 110 120 130 140 pF1KA1 DAPGMEEGAPVFPLGYQYPSLDQLADMIPCVLQYLNFSTIIGVGVGAGAYILARYALNHP ::::.. :: :: :::.::..::: :.: :.:...:. .::.:::::::.::..:: : CCDS45 DAPGQQVGASQFPQGYQFPSMEQLAAMLPSVVQHFGFKYVIGIGVGAGAYVLAKFALIFP 130 140 150 160 170 180 150 160 170 180 190 200 pF1KA1 DTVEGLVLINIDPNAKGWMDWAAHKLTGLTSSIPEMILGHLFSQEELSGNSELIQKYRNI : ::::::.:::::.:::.:::: ::.::::..:. .:.:::::::: .:.::.:.::. CCDS45 DLVEGLVLVNIDPNGKGWIDWAATKLSGLTSTLPDTVLSHLFSQEELVNNTELVQSYRQQ 190 200 210 220 230 240 210 220 230 240 250 260 pF1KA1 ITHAPNLDNIELYWNSYNNRRDLNFERGGDI----TLRCPVMLVVGDQAPHEDAVVECNS : .. : :..:.:: ::.::::...: : . ::::::::::::.:: ::.:::::: CCDS45 IGNVVNQANLQLFWNMYNSRRDLDINRPGTVPNAKTLRCPVMLVVGDNAPAEDGVVECNS 250 260 270 280 290 300 270 280 290 300 310 320 pF1KA1 KLDPTQTSFLKMADSGGQPQLTQPGKLTEAFKYFLQGMGYMASSCMTRLSRSRTASLTSA ::::: :.::::::::: ::.:::::::::::::::::::: :. ::::.:::::::::: CCDS45 KLDPTTTTFLKMADSGGLPQVTQPGKLTEAFKYFLQGMGYMPSASMTRLARSRTASLTSA 310 320 330 340 350 360 330 340 350 pF1KA1 ASVDGNRSRSRTLSQSSESGTLSSGPPGHTMEVSC .::::.: .. : :.:::. : .::::::: CCDS45 SSVDGSRPQACTHSESSEG----LGQVNHTMEVSC 370 380 390 >>CCDS55999.1 NDRG4 gene_id:65009|Hs108|chr16 (369 aa) initn: 1463 init1: 933 opt: 1496 Z-score: 1842.3 bits: 349.5 E(32554): 2.7e-96 Smith-Waterman score: 1496; 64.3% identity (84.1% similar) in 347 aa overlap (17-357:28-369) 10 20 30 40 pF1KA1 MAELQEVQITEEKPLLPGQ--TPEAAKTHSVETPYGSVTFTVYGTPKPK ::. .: . . :..::::: . .. :.:: . CCDS55 MPECWDGVGEGNAGAVKLAGLGDPRWSPGHLLSP-GHQEHDIETPYGLLHVVIRGSPKGN 10 20 30 40 50 50 60 70 80 90 100 pF1KA1 RPAILTYHDVGLNYKSCFQPLFQFEDMQEIIQNFVRVHVDAPGMEEGAPVFPLGYQYPSL :::::::::::::.: ::. .:.::::::: ..:: ::::::.. :: :: :::.::. CCDS55 RPAILTYHDVGLNHKLCFNTFFNFEDMQEITKHFVVCHVDAPGQQVGASQFPQGYQFPSM 60 70 80 90 100 110 110 120 130 140 150 160 pF1KA1 DQLADMIPCVLQYLNFSTIIGVGVGAGAYILARYALNHPDTVEGLVLINIDPNAKGWMDW .::: :.: :.:...:. .::.:::::::.::..:: :: ::::::.:::::.:::.:: CCDS55 EQLAAMLPSVVQHFGFKYVIGIGVGAGAYVLAKFALIFPDLVEGLVLVNIDPNGKGWIDW 120 130 140 150 160 170 170 180 190 200 210 220 pF1KA1 AAHKLTGLTSSIPEMILGHLFSQEELSGNSELIQKYRNIITHAPNLDNIELYWNSYNNRR :: ::.::::..:. .:.:::::::: .:.::.:.::. : .. : :..:.:: ::.:: CCDS55 AATKLSGLTSTLPDTVLSHLFSQEELVNNTELVQSYRQQIGNVVNQANLQLFWNMYNSRR 180 190 200 210 220 230 230 240 250 260 270 280 pF1KA1 DLNFERGGDI----TLRCPVMLVVGDQAPHEDAVVECNSKLDPTQTSFLKMADSGGQPQL ::...: : . ::::::::::::.:: ::.::::::::::: :.::::::::: ::. CCDS55 DLDINRPGTVPNAKTLRCPVMLVVGDNAPAEDGVVECNSKLDPTTTTFLKMADSGGLPQV 240 250 260 270 280 290 290 300 310 320 330 340 pF1KA1 TQPGKLTEAFKYFLQGMGYMASSCMTRLSRSRTASLTSAASVDGNRSRSRTLSQSSESGT :::::::::::::::::::: :. ::::.::::::::::.::::.: .. : :.::: : CCDS55 TQPGKLTEAFKYFLQGMGYMPSASMTRLARSRTASLTSASSVDGSRPQACTHSESSE-GL 300 310 320 330 340 350 350 pF1KA1 LSSGPPGHTMEVSC : .::::::: CCDS55 ---GQVNHTMEVSC 360 >>CCDS58465.1 NDRG4 gene_id:65009|Hs108|chr16 (357 aa) initn: 1463 init1: 933 opt: 1493 Z-score: 1838.8 bits: 348.8 E(32554): 4.2e-96 Smith-Waterman score: 1493; 65.0% identity (84.9% similar) in 337 aa overlap (25-357:25-357) 10 20 30 40 50 60 pF1KA1 MAELQEVQITEEKPLLPGQTPEAAKTHSVETPYGSVTFTVYGTPKPKRPAILTYHDVGLN . :..::::: . .. :.:: .::::::::::::: CCDS58 MPECWDGRSQERRLPRVSSTVSPLQEHDIETPYGLLHVVIRGSPKGNRPAILTYHDVGLN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 YKSCFQPLFQFEDMQEIIQNFVRVHVDAPGMEEGAPVFPLGYQYPSLDQLADMIPCVLQY .: ::. .:.::::::: ..:: ::::::.. :: :: :::.::..::: :.: :.:. CCDS58 HKLCFNTFFNFEDMQEITKHFVVCHVDAPGQQVGASQFPQGYQFPSMEQLAAMLPSVVQH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 LNFSTIIGVGVGAGAYILARYALNHPDTVEGLVLINIDPNAKGWMDWAAHKLTGLTSSIP ..:. .::.:::::::.::..:: :: ::::::.:::::.:::.:::: ::.::::..: CCDS58 FGFKYVIGIGVGAGAYVLAKFALIFPDLVEGLVLVNIDPNGKGWIDWAATKLSGLTSTLP 130 140 150 160 170 180 190 200 210 220 230 pF1KA1 EMILGHLFSQEELSGNSELIQKYRNIITHAPNLDNIELYWNSYNNRRDLNFERGGDI--- . .:.:::::::: .:.::.:.::. : .. : :..:.:: ::.::::...: : . CCDS58 DTVLSHLFSQEELVNNTELVQSYRQQIGNVVNQANLQLFWNMYNSRRDLDINRPGTVPNA 190 200 210 220 230 240 240 250 260 270 280 290 pF1KA1 -TLRCPVMLVVGDQAPHEDAVVECNSKLDPTQTSFLKMADSGGQPQLTQPGKLTEAFKYF ::::::::::::.:: ::.::::::::::: :.::::::::: ::.::::::::::::: CCDS58 KTLRCPVMLVVGDNAPAEDGVVECNSKLDPTTTTFLKMADSGGLPQVTQPGKLTEAFKYF 250 260 270 280 290 300 300 310 320 330 340 350 pF1KA1 LQGMGYMASSCMTRLSRSRTASLTSAASVDGNRSRSRTLSQSSESGTLSSGPPGHTMEVS ::::::: :. ::::.::::::::::.::::.: .. : :.:::. : .:::::: CCDS58 LQGMGYMPSASMTRLARSRTASLTSASSVDGSRPQACTHSESSEG----LGQVNHTMEVS 310 320 330 340 350 pF1KA1 C : CCDS58 C >>CCDS58467.1 NDRG4 gene_id:65009|Hs108|chr16 (339 aa) initn: 1462 init1: 932 opt: 1492 Z-score: 1837.9 bits: 348.5 E(32554): 4.7e-96 Smith-Waterman score: 1492; 65.4% identity (85.1% similar) in 335 aa overlap (27-357:9-339) 10 20 30 40 50 60 pF1KA1 MAELQEVQITEEKPLLPGQTPEAAKTHSVETPYGSVTFTVYGTPKPKRPAILTYHDVGLN :..::::: . .. :.:: .::::::::::::: CCDS58 MPECWDGEHDIETPYGLLHVVIRGSPKGNRPAILTYHDVGLN 10 20 30 40 70 80 90 100 110 120 pF1KA1 YKSCFQPLFQFEDMQEIIQNFVRVHVDAPGMEEGAPVFPLGYQYPSLDQLADMIPCVLQY .: ::. .:.::::::: ..:: ::::::.. :: :: :::.::..::: :.: :.:. CCDS58 HKLCFNTFFNFEDMQEITKHFVVCHVDAPGQQVGASQFPQGYQFPSMEQLAAMLPSVVQH 50 60 70 80 90 100 130 140 150 160 170 180 pF1KA1 LNFSTIIGVGVGAGAYILARYALNHPDTVEGLVLINIDPNAKGWMDWAAHKLTGLTSSIP ..:. .::.:::::::.::..:: :: ::::::.:::::.:::.:::: ::.::::..: CCDS58 FGFKYVIGIGVGAGAYVLAKFALIFPDLVEGLVLVNIDPNGKGWIDWAATKLSGLTSTLP 110 120 130 140 150 160 190 200 210 220 230 pF1KA1 EMILGHLFSQEELSGNSELIQKYRNIITHAPNLDNIELYWNSYNNRRDLNFERGGDI--- . .:.:::::::: .:.::.:.::. : .. : :..:.:: ::.::::...: : . CCDS58 DTVLSHLFSQEELVNNTELVQSYRQQIGNVVNQANLQLFWNMYNSRRDLDINRPGTVPNA 170 180 190 200 210 220 240 250 260 270 280 290 pF1KA1 -TLRCPVMLVVGDQAPHEDAVVECNSKLDPTQTSFLKMADSGGQPQLTQPGKLTEAFKYF ::::::::::::.:: ::.::::::::::: :.::::::::: ::.::::::::::::: CCDS58 KTLRCPVMLVVGDNAPAEDGVVECNSKLDPTTTTFLKMADSGGLPQVTQPGKLTEAFKYF 230 240 250 260 270 280 300 310 320 330 340 350 pF1KA1 LQGMGYMASSCMTRLSRSRTASLTSAASVDGNRSRSRTLSQSSESGTLSSGPPGHTMEVS ::::::: :. ::::.::::::::::.::::.: .. : :.:::. : .:::::: CCDS58 LQGMGYMPSASMTRLARSRTASLTSASSVDGSRPQACTHSESSEG----LGQVNHTMEVS 290 300 310 320 330 pF1KA1 C : CCDS58 C 357 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 20:50:46 2016 done: Wed Nov 2 20:50:46 2016 Total Scan time: 1.920 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]