FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1265, 831 aa 1>>>pF1KA1265 831 - 831 aa - 831 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.1934+/-0.000458; mu= 11.2455+/- 0.029 mean_var=127.7464+/-25.809, 0's: 0 Z-trim(113.9): 101 B-trim: 116 in 1/51 Lambda= 0.113475 statistics sampled from 23430 (23531) to 23430 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.622), E-opt: 0.2 (0.276), width: 16 Scan time: 10.310 The best scores are: opt bits E(85289) XP_011509808 (OMIM: 608733) PREDICTED: zinc transp ( 831) 5752 954.0 0 XP_011509807 (OMIM: 608733) PREDICTED: zinc transp ( 831) 5752 954.0 0 XP_005246746 (OMIM: 608733) PREDICTED: zinc transp ( 831) 5752 954.0 0 XP_011509806 (OMIM: 608733) PREDICTED: zinc transp ( 831) 5752 954.0 0 NP_001120729 (OMIM: 608733) zinc transporter ZIP10 ( 831) 5752 954.0 0 NP_065075 (OMIM: 608733) zinc transporter ZIP10 pr ( 831) 5752 954.0 0 XP_011509809 (OMIM: 608733) PREDICTED: zinc transp ( 718) 5003 831.3 0 XP_016860011 (OMIM: 608733) PREDICTED: zinc transp ( 718) 5003 831.3 0 XP_016860012 (OMIM: 608733) PREDICTED: zinc transp ( 450) 2853 479.2 1.7e-134 NP_036451 (OMIM: 608731) zinc transporter ZIP6 iso ( 755) 1532 263.1 3.4e-69 XP_011524202 (OMIM: 608731) PREDICTED: zinc transp ( 755) 1527 262.3 5.9e-69 XP_011524203 (OMIM: 608731) PREDICTED: zinc transp ( 755) 1527 262.3 5.9e-69 NP_001092876 (OMIM: 608731) zinc transporter ZIP6 ( 433) 1242 215.5 4.2e-55 XP_005273523 (OMIM: 608736,617013) PREDICTED: zinc ( 492) 563 104.4 1.3e-21 XP_006716387 (OMIM: 608736,617013) PREDICTED: zinc ( 492) 563 104.4 1.3e-21 NP_001121903 (OMIM: 608736,617013) zinc transporte ( 492) 563 104.4 1.3e-21 XP_011542780 (OMIM: 608736,617013) PREDICTED: zinc ( 492) 563 104.4 1.3e-21 XP_005273522 (OMIM: 608736,617013) PREDICTED: zinc ( 492) 563 104.4 1.3e-21 NP_001128625 (OMIM: 608736,617013) zinc transporte ( 492) 563 104.4 1.3e-21 XP_016868784 (OMIM: 608736,617013) PREDICTED: zinc ( 492) 563 104.4 1.3e-21 NP_056174 (OMIM: 608736,617013) zinc transporter Z ( 492) 563 104.4 1.3e-21 XP_016868783 (OMIM: 608736,617013) PREDICTED: zinc ( 492) 563 104.4 1.3e-21 XP_006716386 (OMIM: 608736,617013) PREDICTED: zinc ( 502) 563 104.4 1.4e-21 XP_016868782 (OMIM: 608736,617013) PREDICTED: zinc ( 502) 563 104.4 1.4e-21 XP_016868781 (OMIM: 608736,617013) PREDICTED: zinc ( 502) 563 104.4 1.4e-21 XP_016874676 (OMIM: 608730,615946) PREDICTED: zinc ( 288) 553 102.6 2.7e-21 XP_016874675 (OMIM: 608730,615946) PREDICTED: zinc ( 288) 553 102.6 2.7e-21 XP_011536503 (OMIM: 608730,615946) PREDICTED: zinc ( 540) 553 102.7 4.5e-21 NP_775867 (OMIM: 608730,615946) zinc transporter Z ( 540) 553 102.7 4.5e-21 NP_001128667 (OMIM: 608730,615946) zinc transporte ( 540) 553 102.7 4.5e-21 XP_011536501 (OMIM: 608730,615946) PREDICTED: zinc ( 540) 553 102.7 4.5e-21 XP_011536502 (OMIM: 608730,615946) PREDICTED: zinc ( 540) 553 102.7 4.5e-21 XP_011536500 (OMIM: 608730,615946) PREDICTED: zinc ( 540) 553 102.7 4.5e-21 XP_005268860 (OMIM: 608730,615946) PREDICTED: zinc ( 540) 553 102.7 4.5e-21 NP_001269663 (OMIM: 608734) zinc transporter ZIP12 ( 557) 541 100.8 1.8e-20 NP_689938 (OMIM: 608734) zinc transporter ZIP12 is ( 654) 541 100.8 2.1e-20 NP_001267486 (OMIM: 201100,607059) zinc transporte ( 149) 530 98.6 2.1e-20 NP_001269662 (OMIM: 608734) zinc transporter ZIP12 ( 690) 541 100.8 2.1e-20 NP_001138667 (OMIM: 608734) zinc transporter ZIP12 ( 691) 541 100.8 2.1e-20 NP_060237 (OMIM: 201100,607059) zinc transporter Z ( 622) 533 99.5 4.9e-20 NP_570901 (OMIM: 201100,607059) zinc transporter Z ( 647) 533 99.5 5e-20 XP_011530484 (OMIM: 608732,616721) PREDICTED: zinc ( 246) 506 94.8 4.9e-19 NP_001128620 (OMIM: 608732,616721) zinc transporte ( 393) 506 95.0 7.2e-19 XP_016864030 (OMIM: 608732,616721) PREDICTED: zinc ( 393) 506 95.0 7.2e-19 NP_071437 (OMIM: 608732,616721) zinc transporter Z ( 460) 506 95.0 8.2e-19 XP_016864029 (OMIM: 608732,616721) PREDICTED: zinc ( 460) 506 95.0 8.2e-19 NP_001128618 (OMIM: 608732,616721) zinc transporte ( 460) 506 95.0 8.2e-19 XP_005263234 (OMIM: 608732,616721) PREDICTED: zinc ( 460) 506 95.0 8.2e-19 NP_001128619 (OMIM: 608732,616721) zinc transporte ( 444) 458 87.1 1.8e-16 XP_016864031 (OMIM: 608732,616721) PREDICTED: zinc ( 475) 458 87.2 1.9e-16 >>XP_011509808 (OMIM: 608733) PREDICTED: zinc transporte (831 aa) initn: 5752 init1: 5752 opt: 5752 Z-score: 5096.4 bits: 954.0 E(85289): 0 Smith-Waterman score: 5752; 100.0% identity (100.0% similar) in 831 aa overlap (1-831:1-831) 10 20 30 40 50 60 pF1KA1 MKVHMHTKFCLICLLTFIFHHCNHCHEEHDHGPEALHRQHRGMTELEPSKFSKQAAENEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKVHMHTKFCLICLLTFIFHHCNHCHEEHDHGPEALHRQHRGMTELEPSKFSKQAAENEK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 KYYIEKLFERYGENGRLSFFGLEKLLTNLGLGERKVVEINHEDLGHDHVSHLDILAVQEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KYYIEKLFERYGENGRLSFFGLEKLLTNLGLGERKVVEINHEDLGHDHVSHLDILAVQEG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 KHFHSHNHQHSHNHLNSENQTVTSVSTKRNHKCDPEKETVEVSVKSDDKHMHDHNHRLRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KHFHSHNHQHSHNHLNSENQTVTSVSTKRNHKCDPEKETVEVSVKSDDKHMHDHNHRLRH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 HHRLHHHLDHNNTHHFHNDSITPSERGEPSNEPSTETNKTQEQSDVKLPKGKRKKKGRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HHRLHHHLDHNNTHHFHNDSITPSERGEPSNEPSTETNKTQEQSDVKLPKGKRKKKGRKS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 NENSEVITPGFPPNHDQGEQYEHNRVHKPDRVHNPGHSHVHLPERNGHDPGRGHQDLDPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NENSEVITPGFPPNHDQGEQYEHNRVHKPDRVHNPGHSHVHLPERNGHDPGRGHQDLDPD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 NEGELRHTRKREAPHVKNNAIISLRKDLNEDDHHHECLNVTQLLKYYGHGANSPISTDLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NEGELRHTRKREAPHVKNNAIISLRKDLNEDDHHHECLNVTQLLKYYGHGANSPISTDLF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 TYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVPEDEANIGASAWICGIISITVISLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVPEDEANIGASAWICGIISITVISLL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 SLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDALLHLLPHSQGGHDHSHQHAHGHGHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDALLHLLPHSQGGHDHSHQHAHGHGHS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 HGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIRMFKHYKQQRGKQKWFMKQNTEEST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIRMFKHYKQQRGKQKWFMKQNTEEST 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 IGRKLSDHKLNNTPDSDWLQLKPLAGTDDSVVSEDRLNETELTDLEGQQESPPKNYLCIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IGRKLSDHKLNNTPDSDWLQLKPLAGTDDSVVSEDRLNETELTDLEGQQESPPKNYLCIE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 EEKIIDHSHSDGLHTIHEHDLHAAAHNHHGENKTVLRKHNHQWHHKHSHHSHGPCHSGSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEKIIDHSHSDGLHTIHEHDLHAAAHNHHGENKTVLRKHNHQWHHKHSHHSHGPCHSGSD 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 LKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELGDFAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELGDFAV 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 LLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVTAGMFLYVALVDML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVTAGMFLYVALVDML 730 740 750 760 770 780 790 800 810 820 830 pF1KA1 PEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYEDKIVFDIQF ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYEDKIVFDIQF 790 800 810 820 830 >>XP_011509807 (OMIM: 608733) PREDICTED: zinc transporte (831 aa) initn: 5752 init1: 5752 opt: 5752 Z-score: 5096.4 bits: 954.0 E(85289): 0 Smith-Waterman score: 5752; 100.0% identity (100.0% similar) in 831 aa overlap (1-831:1-831) 10 20 30 40 50 60 pF1KA1 MKVHMHTKFCLICLLTFIFHHCNHCHEEHDHGPEALHRQHRGMTELEPSKFSKQAAENEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKVHMHTKFCLICLLTFIFHHCNHCHEEHDHGPEALHRQHRGMTELEPSKFSKQAAENEK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 KYYIEKLFERYGENGRLSFFGLEKLLTNLGLGERKVVEINHEDLGHDHVSHLDILAVQEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KYYIEKLFERYGENGRLSFFGLEKLLTNLGLGERKVVEINHEDLGHDHVSHLDILAVQEG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 KHFHSHNHQHSHNHLNSENQTVTSVSTKRNHKCDPEKETVEVSVKSDDKHMHDHNHRLRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KHFHSHNHQHSHNHLNSENQTVTSVSTKRNHKCDPEKETVEVSVKSDDKHMHDHNHRLRH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 HHRLHHHLDHNNTHHFHNDSITPSERGEPSNEPSTETNKTQEQSDVKLPKGKRKKKGRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HHRLHHHLDHNNTHHFHNDSITPSERGEPSNEPSTETNKTQEQSDVKLPKGKRKKKGRKS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 NENSEVITPGFPPNHDQGEQYEHNRVHKPDRVHNPGHSHVHLPERNGHDPGRGHQDLDPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NENSEVITPGFPPNHDQGEQYEHNRVHKPDRVHNPGHSHVHLPERNGHDPGRGHQDLDPD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 NEGELRHTRKREAPHVKNNAIISLRKDLNEDDHHHECLNVTQLLKYYGHGANSPISTDLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NEGELRHTRKREAPHVKNNAIISLRKDLNEDDHHHECLNVTQLLKYYGHGANSPISTDLF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 TYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVPEDEANIGASAWICGIISITVISLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVPEDEANIGASAWICGIISITVISLL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 SLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDALLHLLPHSQGGHDHSHQHAHGHGHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDALLHLLPHSQGGHDHSHQHAHGHGHS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 HGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIRMFKHYKQQRGKQKWFMKQNTEEST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIRMFKHYKQQRGKQKWFMKQNTEEST 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 IGRKLSDHKLNNTPDSDWLQLKPLAGTDDSVVSEDRLNETELTDLEGQQESPPKNYLCIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IGRKLSDHKLNNTPDSDWLQLKPLAGTDDSVVSEDRLNETELTDLEGQQESPPKNYLCIE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 EEKIIDHSHSDGLHTIHEHDLHAAAHNHHGENKTVLRKHNHQWHHKHSHHSHGPCHSGSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEKIIDHSHSDGLHTIHEHDLHAAAHNHHGENKTVLRKHNHQWHHKHSHHSHGPCHSGSD 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 LKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELGDFAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELGDFAV 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 LLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVTAGMFLYVALVDML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVTAGMFLYVALVDML 730 740 750 760 770 780 790 800 810 820 830 pF1KA1 PEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYEDKIVFDIQF ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYEDKIVFDIQF 790 800 810 820 830 >>XP_005246746 (OMIM: 608733) PREDICTED: zinc transporte (831 aa) initn: 5752 init1: 5752 opt: 5752 Z-score: 5096.4 bits: 954.0 E(85289): 0 Smith-Waterman score: 5752; 100.0% identity (100.0% similar) in 831 aa overlap (1-831:1-831) 10 20 30 40 50 60 pF1KA1 MKVHMHTKFCLICLLTFIFHHCNHCHEEHDHGPEALHRQHRGMTELEPSKFSKQAAENEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MKVHMHTKFCLICLLTFIFHHCNHCHEEHDHGPEALHRQHRGMTELEPSKFSKQAAENEK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 KYYIEKLFERYGENGRLSFFGLEKLLTNLGLGERKVVEINHEDLGHDHVSHLDILAVQEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KYYIEKLFERYGENGRLSFFGLEKLLTNLGLGERKVVEINHEDLGHDHVSHLDILAVQEG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 KHFHSHNHQHSHNHLNSENQTVTSVSTKRNHKCDPEKETVEVSVKSDDKHMHDHNHRLRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KHFHSHNHQHSHNHLNSENQTVTSVSTKRNHKCDPEKETVEVSVKSDDKHMHDHNHRLRH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 HHRLHHHLDHNNTHHFHNDSITPSERGEPSNEPSTETNKTQEQSDVKLPKGKRKKKGRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HHRLHHHLDHNNTHHFHNDSITPSERGEPSNEPSTETNKTQEQSDVKLPKGKRKKKGRKS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 NENSEVITPGFPPNHDQGEQYEHNRVHKPDRVHNPGHSHVHLPERNGHDPGRGHQDLDPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NENSEVITPGFPPNHDQGEQYEHNRVHKPDRVHNPGHSHVHLPERNGHDPGRGHQDLDPD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 NEGELRHTRKREAPHVKNNAIISLRKDLNEDDHHHECLNVTQLLKYYGHGANSPISTDLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NEGELRHTRKREAPHVKNNAIISLRKDLNEDDHHHECLNVTQLLKYYGHGANSPISTDLF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 TYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVPEDEANIGASAWICGIISITVISLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVPEDEANIGASAWICGIISITVISLL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 SLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDALLHLLPHSQGGHDHSHQHAHGHGHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDALLHLLPHSQGGHDHSHQHAHGHGHS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 HGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIRMFKHYKQQRGKQKWFMKQNTEEST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIRMFKHYKQQRGKQKWFMKQNTEEST 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 IGRKLSDHKLNNTPDSDWLQLKPLAGTDDSVVSEDRLNETELTDLEGQQESPPKNYLCIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IGRKLSDHKLNNTPDSDWLQLKPLAGTDDSVVSEDRLNETELTDLEGQQESPPKNYLCIE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 EEKIIDHSHSDGLHTIHEHDLHAAAHNHHGENKTVLRKHNHQWHHKHSHHSHGPCHSGSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EEKIIDHSHSDGLHTIHEHDLHAAAHNHHGENKTVLRKHNHQWHHKHSHHSHGPCHSGSD 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 LKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELGDFAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELGDFAV 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 LLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVTAGMFLYVALVDML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVTAGMFLYVALVDML 730 740 750 760 770 780 790 800 810 820 830 pF1KA1 PEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYEDKIVFDIQF ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYEDKIVFDIQF 790 800 810 820 830 >>XP_011509806 (OMIM: 608733) PREDICTED: zinc transporte (831 aa) initn: 5752 init1: 5752 opt: 5752 Z-score: 5096.4 bits: 954.0 E(85289): 0 Smith-Waterman score: 5752; 100.0% identity (100.0% similar) in 831 aa overlap (1-831:1-831) 10 20 30 40 50 60 pF1KA1 MKVHMHTKFCLICLLTFIFHHCNHCHEEHDHGPEALHRQHRGMTELEPSKFSKQAAENEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKVHMHTKFCLICLLTFIFHHCNHCHEEHDHGPEALHRQHRGMTELEPSKFSKQAAENEK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 KYYIEKLFERYGENGRLSFFGLEKLLTNLGLGERKVVEINHEDLGHDHVSHLDILAVQEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KYYIEKLFERYGENGRLSFFGLEKLLTNLGLGERKVVEINHEDLGHDHVSHLDILAVQEG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 KHFHSHNHQHSHNHLNSENQTVTSVSTKRNHKCDPEKETVEVSVKSDDKHMHDHNHRLRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KHFHSHNHQHSHNHLNSENQTVTSVSTKRNHKCDPEKETVEVSVKSDDKHMHDHNHRLRH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 HHRLHHHLDHNNTHHFHNDSITPSERGEPSNEPSTETNKTQEQSDVKLPKGKRKKKGRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HHRLHHHLDHNNTHHFHNDSITPSERGEPSNEPSTETNKTQEQSDVKLPKGKRKKKGRKS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 NENSEVITPGFPPNHDQGEQYEHNRVHKPDRVHNPGHSHVHLPERNGHDPGRGHQDLDPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NENSEVITPGFPPNHDQGEQYEHNRVHKPDRVHNPGHSHVHLPERNGHDPGRGHQDLDPD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 NEGELRHTRKREAPHVKNNAIISLRKDLNEDDHHHECLNVTQLLKYYGHGANSPISTDLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NEGELRHTRKREAPHVKNNAIISLRKDLNEDDHHHECLNVTQLLKYYGHGANSPISTDLF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 TYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVPEDEANIGASAWICGIISITVISLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVPEDEANIGASAWICGIISITVISLL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 SLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDALLHLLPHSQGGHDHSHQHAHGHGHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDALLHLLPHSQGGHDHSHQHAHGHGHS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 HGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIRMFKHYKQQRGKQKWFMKQNTEEST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIRMFKHYKQQRGKQKWFMKQNTEEST 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 IGRKLSDHKLNNTPDSDWLQLKPLAGTDDSVVSEDRLNETELTDLEGQQESPPKNYLCIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IGRKLSDHKLNNTPDSDWLQLKPLAGTDDSVVSEDRLNETELTDLEGQQESPPKNYLCIE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 EEKIIDHSHSDGLHTIHEHDLHAAAHNHHGENKTVLRKHNHQWHHKHSHHSHGPCHSGSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEKIIDHSHSDGLHTIHEHDLHAAAHNHHGENKTVLRKHNHQWHHKHSHHSHGPCHSGSD 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 LKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELGDFAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELGDFAV 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 LLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVTAGMFLYVALVDML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVTAGMFLYVALVDML 730 740 750 760 770 780 790 800 810 820 830 pF1KA1 PEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYEDKIVFDIQF ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYEDKIVFDIQF 790 800 810 820 830 >>NP_001120729 (OMIM: 608733) zinc transporter ZIP10 pre (831 aa) initn: 5752 init1: 5752 opt: 5752 Z-score: 5096.4 bits: 954.0 E(85289): 0 Smith-Waterman score: 5752; 100.0% identity (100.0% similar) in 831 aa overlap (1-831:1-831) 10 20 30 40 50 60 pF1KA1 MKVHMHTKFCLICLLTFIFHHCNHCHEEHDHGPEALHRQHRGMTELEPSKFSKQAAENEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKVHMHTKFCLICLLTFIFHHCNHCHEEHDHGPEALHRQHRGMTELEPSKFSKQAAENEK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 KYYIEKLFERYGENGRLSFFGLEKLLTNLGLGERKVVEINHEDLGHDHVSHLDILAVQEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KYYIEKLFERYGENGRLSFFGLEKLLTNLGLGERKVVEINHEDLGHDHVSHLDILAVQEG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 KHFHSHNHQHSHNHLNSENQTVTSVSTKRNHKCDPEKETVEVSVKSDDKHMHDHNHRLRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KHFHSHNHQHSHNHLNSENQTVTSVSTKRNHKCDPEKETVEVSVKSDDKHMHDHNHRLRH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 HHRLHHHLDHNNTHHFHNDSITPSERGEPSNEPSTETNKTQEQSDVKLPKGKRKKKGRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HHRLHHHLDHNNTHHFHNDSITPSERGEPSNEPSTETNKTQEQSDVKLPKGKRKKKGRKS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 NENSEVITPGFPPNHDQGEQYEHNRVHKPDRVHNPGHSHVHLPERNGHDPGRGHQDLDPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NENSEVITPGFPPNHDQGEQYEHNRVHKPDRVHNPGHSHVHLPERNGHDPGRGHQDLDPD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 NEGELRHTRKREAPHVKNNAIISLRKDLNEDDHHHECLNVTQLLKYYGHGANSPISTDLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NEGELRHTRKREAPHVKNNAIISLRKDLNEDDHHHECLNVTQLLKYYGHGANSPISTDLF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 TYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVPEDEANIGASAWICGIISITVISLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVPEDEANIGASAWICGIISITVISLL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 SLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDALLHLLPHSQGGHDHSHQHAHGHGHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDALLHLLPHSQGGHDHSHQHAHGHGHS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 HGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIRMFKHYKQQRGKQKWFMKQNTEEST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIRMFKHYKQQRGKQKWFMKQNTEEST 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 IGRKLSDHKLNNTPDSDWLQLKPLAGTDDSVVSEDRLNETELTDLEGQQESPPKNYLCIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IGRKLSDHKLNNTPDSDWLQLKPLAGTDDSVVSEDRLNETELTDLEGQQESPPKNYLCIE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 EEKIIDHSHSDGLHTIHEHDLHAAAHNHHGENKTVLRKHNHQWHHKHSHHSHGPCHSGSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEKIIDHSHSDGLHTIHEHDLHAAAHNHHGENKTVLRKHNHQWHHKHSHHSHGPCHSGSD 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 LKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELGDFAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELGDFAV 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 LLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVTAGMFLYVALVDML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVTAGMFLYVALVDML 730 740 750 760 770 780 790 800 810 820 830 pF1KA1 PEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYEDKIVFDIQF ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYEDKIVFDIQF 790 800 810 820 830 >>NP_065075 (OMIM: 608733) zinc transporter ZIP10 precur (831 aa) initn: 5752 init1: 5752 opt: 5752 Z-score: 5096.4 bits: 954.0 E(85289): 0 Smith-Waterman score: 5752; 100.0% identity (100.0% similar) in 831 aa overlap (1-831:1-831) 10 20 30 40 50 60 pF1KA1 MKVHMHTKFCLICLLTFIFHHCNHCHEEHDHGPEALHRQHRGMTELEPSKFSKQAAENEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 MKVHMHTKFCLICLLTFIFHHCNHCHEEHDHGPEALHRQHRGMTELEPSKFSKQAAENEK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 KYYIEKLFERYGENGRLSFFGLEKLLTNLGLGERKVVEINHEDLGHDHVSHLDILAVQEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 KYYIEKLFERYGENGRLSFFGLEKLLTNLGLGERKVVEINHEDLGHDHVSHLDILAVQEG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 KHFHSHNHQHSHNHLNSENQTVTSVSTKRNHKCDPEKETVEVSVKSDDKHMHDHNHRLRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 KHFHSHNHQHSHNHLNSENQTVTSVSTKRNHKCDPEKETVEVSVKSDDKHMHDHNHRLRH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 HHRLHHHLDHNNTHHFHNDSITPSERGEPSNEPSTETNKTQEQSDVKLPKGKRKKKGRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 HHRLHHHLDHNNTHHFHNDSITPSERGEPSNEPSTETNKTQEQSDVKLPKGKRKKKGRKS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 NENSEVITPGFPPNHDQGEQYEHNRVHKPDRVHNPGHSHVHLPERNGHDPGRGHQDLDPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 NENSEVITPGFPPNHDQGEQYEHNRVHKPDRVHNPGHSHVHLPERNGHDPGRGHQDLDPD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 NEGELRHTRKREAPHVKNNAIISLRKDLNEDDHHHECLNVTQLLKYYGHGANSPISTDLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 NEGELRHTRKREAPHVKNNAIISLRKDLNEDDHHHECLNVTQLLKYYGHGANSPISTDLF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 TYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVPEDEANIGASAWICGIISITVISLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 TYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVPEDEANIGASAWICGIISITVISLL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 SLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDALLHLLPHSQGGHDHSHQHAHGHGHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 SLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDALLHLLPHSQGGHDHSHQHAHGHGHS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 HGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIRMFKHYKQQRGKQKWFMKQNTEEST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 HGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIRMFKHYKQQRGKQKWFMKQNTEEST 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 IGRKLSDHKLNNTPDSDWLQLKPLAGTDDSVVSEDRLNETELTDLEGQQESPPKNYLCIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 IGRKLSDHKLNNTPDSDWLQLKPLAGTDDSVVSEDRLNETELTDLEGQQESPPKNYLCIE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 EEKIIDHSHSDGLHTIHEHDLHAAAHNHHGENKTVLRKHNHQWHHKHSHHSHGPCHSGSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 EEKIIDHSHSDGLHTIHEHDLHAAAHNHHGENKTVLRKHNHQWHHKHSHHSHGPCHSGSD 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 LKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELGDFAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 LKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELGDFAV 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 LLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVTAGMFLYVALVDML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 LLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVTAGMFLYVALVDML 730 740 750 760 770 780 790 800 810 820 830 pF1KA1 PEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYEDKIVFDIQF ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 PEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYEDKIVFDIQF 790 800 810 820 830 >>XP_011509809 (OMIM: 608733) PREDICTED: zinc transporte (718 aa) initn: 5003 init1: 5003 opt: 5003 Z-score: 4434.7 bits: 831.3 E(85289): 0 Smith-Waterman score: 5003; 100.0% identity (100.0% similar) in 716 aa overlap (1-716:1-716) 10 20 30 40 50 60 pF1KA1 MKVHMHTKFCLICLLTFIFHHCNHCHEEHDHGPEALHRQHRGMTELEPSKFSKQAAENEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKVHMHTKFCLICLLTFIFHHCNHCHEEHDHGPEALHRQHRGMTELEPSKFSKQAAENEK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 KYYIEKLFERYGENGRLSFFGLEKLLTNLGLGERKVVEINHEDLGHDHVSHLDILAVQEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KYYIEKLFERYGENGRLSFFGLEKLLTNLGLGERKVVEINHEDLGHDHVSHLDILAVQEG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 KHFHSHNHQHSHNHLNSENQTVTSVSTKRNHKCDPEKETVEVSVKSDDKHMHDHNHRLRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KHFHSHNHQHSHNHLNSENQTVTSVSTKRNHKCDPEKETVEVSVKSDDKHMHDHNHRLRH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 HHRLHHHLDHNNTHHFHNDSITPSERGEPSNEPSTETNKTQEQSDVKLPKGKRKKKGRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HHRLHHHLDHNNTHHFHNDSITPSERGEPSNEPSTETNKTQEQSDVKLPKGKRKKKGRKS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 NENSEVITPGFPPNHDQGEQYEHNRVHKPDRVHNPGHSHVHLPERNGHDPGRGHQDLDPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NENSEVITPGFPPNHDQGEQYEHNRVHKPDRVHNPGHSHVHLPERNGHDPGRGHQDLDPD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 NEGELRHTRKREAPHVKNNAIISLRKDLNEDDHHHECLNVTQLLKYYGHGANSPISTDLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NEGELRHTRKREAPHVKNNAIISLRKDLNEDDHHHECLNVTQLLKYYGHGANSPISTDLF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 TYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVPEDEANIGASAWICGIISITVISLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVPEDEANIGASAWICGIISITVISLL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 SLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDALLHLLPHSQGGHDHSHQHAHGHGHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDALLHLLPHSQGGHDHSHQHAHGHGHS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 HGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIRMFKHYKQQRGKQKWFMKQNTEEST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIRMFKHYKQQRGKQKWFMKQNTEEST 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 IGRKLSDHKLNNTPDSDWLQLKPLAGTDDSVVSEDRLNETELTDLEGQQESPPKNYLCIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IGRKLSDHKLNNTPDSDWLQLKPLAGTDDSVVSEDRLNETELTDLEGQQESPPKNYLCIE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 EEKIIDHSHSDGLHTIHEHDLHAAAHNHHGENKTVLRKHNHQWHHKHSHHSHGPCHSGSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEKIIDHSHSDGLHTIHEHDLHAAAHNHHGENKTVLRKHNHQWHHKHSHHSHGPCHSGSD 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 LKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELGDFAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELGSH 670 680 690 700 710 730 740 750 760 770 780 pF1KA1 LLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVTAGMFLYVALVDML >>XP_016860011 (OMIM: 608733) PREDICTED: zinc transporte (718 aa) initn: 5003 init1: 5003 opt: 5003 Z-score: 4434.7 bits: 831.3 E(85289): 0 Smith-Waterman score: 5003; 100.0% identity (100.0% similar) in 716 aa overlap (1-716:1-716) 10 20 30 40 50 60 pF1KA1 MKVHMHTKFCLICLLTFIFHHCNHCHEEHDHGPEALHRQHRGMTELEPSKFSKQAAENEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MKVHMHTKFCLICLLTFIFHHCNHCHEEHDHGPEALHRQHRGMTELEPSKFSKQAAENEK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 KYYIEKLFERYGENGRLSFFGLEKLLTNLGLGERKVVEINHEDLGHDHVSHLDILAVQEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KYYIEKLFERYGENGRLSFFGLEKLLTNLGLGERKVVEINHEDLGHDHVSHLDILAVQEG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 KHFHSHNHQHSHNHLNSENQTVTSVSTKRNHKCDPEKETVEVSVKSDDKHMHDHNHRLRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KHFHSHNHQHSHNHLNSENQTVTSVSTKRNHKCDPEKETVEVSVKSDDKHMHDHNHRLRH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 HHRLHHHLDHNNTHHFHNDSITPSERGEPSNEPSTETNKTQEQSDVKLPKGKRKKKGRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HHRLHHHLDHNNTHHFHNDSITPSERGEPSNEPSTETNKTQEQSDVKLPKGKRKKKGRKS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 NENSEVITPGFPPNHDQGEQYEHNRVHKPDRVHNPGHSHVHLPERNGHDPGRGHQDLDPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NENSEVITPGFPPNHDQGEQYEHNRVHKPDRVHNPGHSHVHLPERNGHDPGRGHQDLDPD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 NEGELRHTRKREAPHVKNNAIISLRKDLNEDDHHHECLNVTQLLKYYGHGANSPISTDLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NEGELRHTRKREAPHVKNNAIISLRKDLNEDDHHHECLNVTQLLKYYGHGANSPISTDLF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 TYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVPEDEANIGASAWICGIISITVISLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVPEDEANIGASAWICGIISITVISLL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 SLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDALLHLLPHSQGGHDHSHQHAHGHGHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDALLHLLPHSQGGHDHSHQHAHGHGHS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 HGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIRMFKHYKQQRGKQKWFMKQNTEEST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIRMFKHYKQQRGKQKWFMKQNTEEST 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 IGRKLSDHKLNNTPDSDWLQLKPLAGTDDSVVSEDRLNETELTDLEGQQESPPKNYLCIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IGRKLSDHKLNNTPDSDWLQLKPLAGTDDSVVSEDRLNETELTDLEGQQESPPKNYLCIE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 EEKIIDHSHSDGLHTIHEHDLHAAAHNHHGENKTVLRKHNHQWHHKHSHHSHGPCHSGSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEKIIDHSHSDGLHTIHEHDLHAAAHNHHGENKTVLRKHNHQWHHKHSHHSHGPCHSGSD 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 LKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELGDFAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELGSH 670 680 690 700 710 730 740 750 760 770 780 pF1KA1 LLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVTAGMFLYVALVDML >>XP_016860012 (OMIM: 608733) PREDICTED: zinc transporte (450 aa) initn: 2853 init1: 2853 opt: 2853 Z-score: 2535.4 bits: 479.2 E(85289): 1.7e-134 Smith-Waterman score: 2853; 100.0% identity (100.0% similar) in 405 aa overlap (1-405:1-405) 10 20 30 40 50 60 pF1KA1 MKVHMHTKFCLICLLTFIFHHCNHCHEEHDHGPEALHRQHRGMTELEPSKFSKQAAENEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MKVHMHTKFCLICLLTFIFHHCNHCHEEHDHGPEALHRQHRGMTELEPSKFSKQAAENEK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 KYYIEKLFERYGENGRLSFFGLEKLLTNLGLGERKVVEINHEDLGHDHVSHLDILAVQEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KYYIEKLFERYGENGRLSFFGLEKLLTNLGLGERKVVEINHEDLGHDHVSHLDILAVQEG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 KHFHSHNHQHSHNHLNSENQTVTSVSTKRNHKCDPEKETVEVSVKSDDKHMHDHNHRLRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KHFHSHNHQHSHNHLNSENQTVTSVSTKRNHKCDPEKETVEVSVKSDDKHMHDHNHRLRH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 HHRLHHHLDHNNTHHFHNDSITPSERGEPSNEPSTETNKTQEQSDVKLPKGKRKKKGRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HHRLHHHLDHNNTHHFHNDSITPSERGEPSNEPSTETNKTQEQSDVKLPKGKRKKKGRKS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 NENSEVITPGFPPNHDQGEQYEHNRVHKPDRVHNPGHSHVHLPERNGHDPGRGHQDLDPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NENSEVITPGFPPNHDQGEQYEHNRVHKPDRVHNPGHSHVHLPERNGHDPGRGHQDLDPD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 NEGELRHTRKREAPHVKNNAIISLRKDLNEDDHHHECLNVTQLLKYYGHGANSPISTDLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NEGELRHTRKREAPHVKNNAIISLRKDLNEDDHHHECLNVTQLLKYYGHGANSPISTDLF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 TYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVPEDEANIGASAWICGIISITVISLL ::::::::::::::::::::::::::::::::::::::::::::: XP_016 TYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVPEDEANIGASGSFFIVPTWLHLGVH 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 SLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDALLHLLPHSQGGHDHSHQHAHGHGHS XP_016 RYLPLNISKLILHTKFVPLNGSQISLISFF 430 440 450 >>NP_036451 (OMIM: 608731) zinc transporter ZIP6 isoform (755 aa) initn: 1545 init1: 783 opt: 1532 Z-score: 1363.4 bits: 263.1 E(85289): 3.4e-69 Smith-Waterman score: 1648; 36.8% identity (63.4% similar) in 853 aa overlap (5-831:1-755) 10 20 30 40 50 60 pF1KA1 MKVHMHTKFCLICLLTFIFHHCNHCHEEHDHGPEALHRQHRGMTELEPSKFSKQAAENEK : :. .: .::: . : :: . :. . . .. : .. . : . . NP_036 MARKLSVILILTFALSVTNPLHELK---AAAFPQTTEKISPNWESGINVDLAISTR 10 20 30 40 50 70 80 90 100 110 pF1KA1 KYYIEKLFERYGENGRLSFFGLEKLLTNLGLGERKVVEINHEDLGH-DHVSHLDILAVQE .:....:: :::::. :: :..::: :.:. . : ..:.:. : :: : : .. NP_036 QYHLQQLFYRYGENNSLSVEGFRKLLQNIGIDKIKRIHIHHDHDHHSDHEHHSDHERHSD 60 70 80 90 100 110 120 130 140 150 160 170 pF1KA1 GKHFHSHNHQHSHNHLNSENQTVTSVSTKRNHKCDPEKETVEVSVKSDDKHMHDHNHRLR .: .:.:. .:.: . .:..... ..::. : :... ::.. .: . . NP_036 HEHHSDHEHHSDHDHHSHHNHAASG-KNKRKALC-PDHD-------SDSSGKDPRNSQGK 120 130 140 150 160 180 190 200 210 220 230 pF1KA1 HHHRLHHHLDHNNTHHFHNDSITPSERGEPSNEPSTETNKTQEQSDVKLPK-GKRKKKGR :: .: . :. .::.. :: :. .: .. :. .. :. :: : NP_036 GAHRPEHASGRRNV----KDSVSASEV--TSTVYNTVSEGTHFLETIETPRPGKLFPKD- 170 180 190 200 210 240 250 260 270 280 290 pF1KA1 KSNENSEVITPGFPPNHDQGEQYEHNRVHK-PDRVHNPGHSHVHLPERNGHDPGRGHQDL .. . ::. . ..:: . : : . : .: .: . NP_036 --------VSSSTPPSVTS-----KSRVSRLAGRKTNESVS----------EPRKGFM-- 220 230 240 250 300 310 320 330 340 350 pF1KA1 DPDNEGELRHTRKREAPHVKNNAIISLRKDLNEDDHHHECLNVTQLLKYYGHGANSPIST ..: : ... .::.:...:: .: : . :... NP_036 ---------YSR-------------------NTNENPQECFNASKLLTSHGMGIQVPLNA 260 270 280 360 370 380 390 400 410 pF1KA1 DLFTYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVPEDEANIGASAWICGIISITVI :.:::::.. :::.: :. : .. : .: .. ::. :.:.:..: NP_036 TEFNYLCPAIINQIDARSCLIH--------TSEKKAEIPPKTYSLQI-AWVGGFIAISII 290 300 310 320 330 420 430 440 450 460 470 pF1KA1 SLLSLLGVILVPIINQGCFKFLLTFLVALAVGTMSGDALLHLLPHSQGGHDHSHQHAHG- :.::::::::::..:. :::::.:::::::::.::::.:::::::...: :::.: . NP_036 SFLSLLGVILVPLMNRVFFKFLLSFLVALAVGTLSGDAFLHLLPHSHASHHHSHSHEEPA 340 350 360 370 380 390 480 490 500 510 520 pF1KA1 ----HGHSHGHESNKFLEE---YDAVLKGLVALGGIYLLFIIEHCIRMFKHYKQQRGKQK .: .: :.. .:: .:.. :::.::::.:..:..:: . ..:..:... :.. NP_036 MEMKRGPLFSHLSSQNIEESAYFDSTWKGLTALGGLYFMFLVEHVLTLIKQFKDKK-KKN 400 410 420 430 440 450 530 540 550 560 570 580 pF1KA1 WFMKQNTEESTIGRKLSDHKLNNTPDSDWLQLKPLAGTDDSVVSEDRLNETELTDLEGQQ .: .. : ..:: .. . . . . .. ::: . . : . : . ...:: NP_036 QKKPENDDDVEIKKQLSKYESQLSTNEEKVD------TDDRTEGYLRADSQEPSHFDSQQ 460 470 480 490 500 590 600 610 620 630 pF1KA1 ESPPKNYLCIEEEKIIDHSHSDGLHT------------IHEHDLHAAAHN---HHGENKT . . ::: .: :.: . ... : :: . . . :: . . NP_036 PA-----VLEEEEVMIAHAHPQEVYNEYVPRGCKNKCHSHFHDTLGQSDDLIHHHHDYHH 510 520 530 540 550 560 640 650 660 670 680 690 pF1KA1 VLRKHNHQWHHKHSHHSHGPCHSGSDLKETGIANIAWMVIMGDGIHNFSDGLAIGAAFSA .:..:.:: :: ::: .. .: .::..:.:..:::::::::.:::::::::::::. NP_036 ILHHHHHQNHHPHSHSQR---YSREELKDAGVATLAWMVIMGDGLHNFSDGLAIGAAFTE 570 580 590 600 610 620 700 710 720 730 740 750 pF1KA1 GLTGGISTSIAVFCHELPHELGDFAVLLKAGMTVKQAIVYNLLSAMMAYIGMLIGTAVGQ ::..:.:::.:::::::::::::::::::::::::::..:: ::::.::.:: : .:. NP_036 GLSSGLSTSVAVFCHELPHELGDFAVLLKAGMTVKQAVLYNALSAMLAYLGMATGIFIGH 630 640 650 660 670 680 760 770 780 790 800 810 pF1KA1 YANNITLWIFAVTAGMFLYVALVDMLPEMLHGDGDNEEHGFCPVGQFILQNLGLLFGFAI ::.:...::::.:::.:.:::::::.:::::.:... :: : :.::: :.:.::.: NP_036 YAENVSMWIFALTAGLFMYVALVDMVPEMLHNDASD--HGCSRWGYFFLQNAGMLLGFGI 690 700 710 720 730 820 830 pF1KA1 MLVIALYEDKIVFDIQF ::.:...: :::: :.: NP_036 MLLISIFEHKIVFRINF 740 750 831 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 20:53:27 2016 done: Wed Nov 2 20:53:29 2016 Total Scan time: 10.310 Total Display time: 0.230 Function used was FASTA [36.3.4 Apr, 2011]