FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1287, 1204 aa 1>>>pF1KA1287 1204 - 1204 aa - 1204 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8262+/-0.00119; mu= 18.9334+/- 0.071 mean_var=62.8375+/-12.561, 0's: 0 Z-trim(100.8): 34 B-trim: 0 in 0/50 Lambda= 0.161795 statistics sampled from 6239 (6249) to 6239 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.54), E-opt: 0.2 (0.192), width: 16 Scan time: 4.080 The best scores are: opt bits E(32554) CCDS45750.1 INTS2 gene_id:57508|Hs108|chr17 (1204) 7828 1836.8 0 CCDS82181.1 INTS2 gene_id:57508|Hs108|chr17 (1196) 7778 1825.2 0 >>CCDS45750.1 INTS2 gene_id:57508|Hs108|chr17 (1204 aa) initn: 7828 init1: 7828 opt: 7828 Z-score: 9861.9 bits: 1836.8 E(32554): 0 Smith-Waterman score: 7828; 99.9% identity (100.0% similar) in 1204 aa overlap (1-1204:1-1204) 10 20 30 40 50 60 pF1KA1 MKDQQTVIMTECTSLQFVSPFAFEAMQKVDVVCLASLSDPELRLLLPCLVRMALCAPADQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 MKDQQTVIMTECTSLQFVSPFAFEAMQKVDVVCLASLSDPELRLLLPCLVRMALCAPADQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 SQSWAQDKKLILRLLSGVEAVNSIVALLSVDFHALEQDASKEQQLRHKLGGGSGESILVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 SQSWAQDKKLILRLLSGVEAVNSIVALLSVDFHALEQDASKEQQLRHKLGGGSGESILVS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 QLQHGLTLEFEHSDSPRRLRLVLSELLAIMNKVSESNGEFFFKSSELFESPVYLEEAADV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 QLQHGLTLEFEHSDSPRRLRLVLSELLAIMNKVSESNGEFFFKSSELFESPVYLEEAADV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 LCILQAELPSLLPIVDVAEALLHVRNGAWFLCLLVANVPDSFNEVCRGLIKNGERQDEES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 LCILQAELPSLLPIVDVAEALLHVRNGAWFLCLLVANVPDSFNEVCRGLIKNGERQDEES 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 LGGRRRTDALRFLCKMNPSQALKVRGMVVEECHLPGLGVALTLDHTKNEACEDGVSDLVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 LGGRRRTDALRFLCKMNPSQALKVRGMVVEECHLPGLGVALTLDHTKNEACEDGVSDLVC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 FVSGLLLGTNAKVRTWFGTFIRNGQQRKRETSSSVLWQMRRQLLLELMGILPTVRSTRIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 FVSGLLLGTNAKVRTWFGTFIRNGQQRKRETSSSVLWQMRRQLLLELMGILPTVRSTRIV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 EEADVDMEPNVSVYSGLKEEHVVKASALLRLYCALMGIAGLKPTEEEAEQLLQLMTSRPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 EEADVDMEPNVSVYSGLKEEHVVKASALLRLYCALMGIAGLKPTEEEAEQLLQLMTSRPP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 ATPAGVRFVSLSFCMLLAFSTLVSTPEQEQLMVVWLSWMIKEEAYFESTSGVSASFGEML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 ATPAGVRFVSLSFCMLLAFSTLVSTPEQEQLMVVWLSWMIKEEAYFESTSGVSASFGEML 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 LLVAMYFHSNQLSAIIDLVCSTLGMKIVIKPSSLSRMKTIFTQEIFTEQVVTAHAVRVPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 LLVAMYFHSNQLSAIIDLVCSTLGMKIVIKPSSLSRMKTIFTQEIFTEQVVTAHAVRVPV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 TSNLSANITGFLPIHCIYQLLRSRSFTKHKVSIKDWIYRQLCETSTPLHPQLLPLIDVYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 TSNLSANITGFLPIHCIYQLLRSRSFTKHKVSIKDWIYRQLCETSTPLHPQLLPLIDVYI 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 NSILTPASKSNPEATNQPVTEQEILNIFQGVIGGDNIRLNQRFSITAQLLVLYYILSYEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 NSILTPASKSNPEATNQPVTEQEILNIFQGVIGGDNIRLNQRFSITAQLLVLYYILSYEE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 ALLANTKTLAAMQRKPKSYSSSLMDQIPIKFLIRQAQGLQQELGGLHSALLRLLATNYPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 ALLANTKTLAAMQRKPKSYSSSLMDQIPIKFLIRQAQGLQQELGGLHSALLRLLATNYPH 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 LCIVDDWICEEEITGTDALLRRMLLTNNAKNHSPKQLQEAFSAVPVNHTQVMQIIEHLTL :::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::: CCDS45 LCIVDDWICEEEITGTDALLRRMLLTNNAKNHSPKQLQEAFSAVPVNNTQVMQIIEHLTL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 LSASELIPYAEVLTSNMSQLLNSGVPRRILQTVNKLWMVLNTVMPRRLWVMTVNALQPSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 LSASELIPYAEVLTSNMSQLLNSGVPRRILQTVNKLWMVLNTVMPRRLWVMTVNALQPSI 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 KFVRQQKYTQNDLMIDPLIVLRCDQRVHRCPPLMDITLHMLNGYLLASKAYLSAHLKETE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 KFVRQQKYTQNDLMIDPLIVLRCDQRVHRCPPLMDITLHMLNGYLLASKAYLSAHLKETE 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 QDRPSQNNTIGLVGQTDAPEVTREELKNALLAAQDSAAVQILLEICLPTEEEKANGVNPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 QDRPSQNNTIGLVGQTDAPEVTREELKNALLAAQDSAAVQILLEICLPTEEEKANGVNPD 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 SLLRNVQSVITTSAPNKGMEEGEDNLLCNLREVQCLICCLLHQMYIADPNIAKLVHFQGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 SLLRNVQSVITTSAPNKGMEEGEDNLLCNLREVQCLICCLLHQMYIADPNIAKLVHFQGY 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA1 PCELLPLTVAGIPSMHICLDFIPELIAQPELEKQIFAIQLLSHLCIQYALPKSLSVARLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 PCELLPLTVAGIPSMHICLDFIPELIAQPELEKQIFAIQLLSHLCIQYALPKSLSVARLA 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA1 VNVMGTLLTVLTQAKRYAFFMPTLPSLVSFCRAFPPLYEDIMSLLIQIGQVCASDVATQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 VNVMGTLLTVLTQAKRYAFFMPTLPSLVSFCRAFPPLYEDIMSLLIQIGQVCASDVATQT 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA1 RDIDPIITRLQQIKEKPSGWSQICKDSSYKNGSRDTGSMDPDVQLCHCIERTVIEIINMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 RDIDPIITRLQQIKEKPSGWSQICKDSSYKNGSRDTGSMDPDVQLCHCIERTVIEIINMS 1150 1160 1170 1180 1190 1200 pF1KA1 VSGI :::: CCDS45 VSGI >>CCDS82181.1 INTS2 gene_id:57508|Hs108|chr17 (1196 aa) initn: 7778 init1: 7778 opt: 7778 Z-score: 9798.9 bits: 1825.2 E(32554): 0 Smith-Waterman score: 7778; 99.9% identity (100.0% similar) in 1196 aa overlap (9-1204:1-1196) 10 20 30 40 50 60 pF1KA1 MKDQQTVIMTECTSLQFVSPFAFEAMQKVDVVCLASLSDPELRLLLPCLVRMALCAPADQ :::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 MTECTSLQFVSPFAFEAMQKVDVVCLASLSDPELRLLLPCLVRMALCAPADQ 10 20 30 40 50 70 80 90 100 110 120 pF1KA1 SQSWAQDKKLILRLLSGVEAVNSIVALLSVDFHALEQDASKEQQLRHKLGGGSGESILVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 SQSWAQDKKLILRLLSGVEAVNSIVALLSVDFHALEQDASKEQQLRHKLGGGSGESILVS 60 70 80 90 100 110 130 140 150 160 170 180 pF1KA1 QLQHGLTLEFEHSDSPRRLRLVLSELLAIMNKVSESNGEFFFKSSELFESPVYLEEAADV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 QLQHGLTLEFEHSDSPRRLRLVLSELLAIMNKVSESNGEFFFKSSELFESPVYLEEAADV 120 130 140 150 160 170 190 200 210 220 230 240 pF1KA1 LCILQAELPSLLPIVDVAEALLHVRNGAWFLCLLVANVPDSFNEVCRGLIKNGERQDEES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 LCILQAELPSLLPIVDVAEALLHVRNGAWFLCLLVANVPDSFNEVCRGLIKNGERQDEES 180 190 200 210 220 230 250 260 270 280 290 300 pF1KA1 LGGRRRTDALRFLCKMNPSQALKVRGMVVEECHLPGLGVALTLDHTKNEACEDGVSDLVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 LGGRRRTDALRFLCKMNPSQALKVRGMVVEECHLPGLGVALTLDHTKNEACEDGVSDLVC 240 250 260 270 280 290 310 320 330 340 350 360 pF1KA1 FVSGLLLGTNAKVRTWFGTFIRNGQQRKRETSSSVLWQMRRQLLLELMGILPTVRSTRIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 FVSGLLLGTNAKVRTWFGTFIRNGQQRKRETSSSVLWQMRRQLLLELMGILPTVRSTRIV 300 310 320 330 340 350 370 380 390 400 410 420 pF1KA1 EEADVDMEPNVSVYSGLKEEHVVKASALLRLYCALMGIAGLKPTEEEAEQLLQLMTSRPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 EEADVDMEPNVSVYSGLKEEHVVKASALLRLYCALMGIAGLKPTEEEAEQLLQLMTSRPP 360 370 380 390 400 410 430 440 450 460 470 480 pF1KA1 ATPAGVRFVSLSFCMLLAFSTLVSTPEQEQLMVVWLSWMIKEEAYFESTSGVSASFGEML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 ATPAGVRFVSLSFCMLLAFSTLVSTPEQEQLMVVWLSWMIKEEAYFESTSGVSASFGEML 420 430 440 450 460 470 490 500 510 520 530 540 pF1KA1 LLVAMYFHSNQLSAIIDLVCSTLGMKIVIKPSSLSRMKTIFTQEIFTEQVVTAHAVRVPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 LLVAMYFHSNQLSAIIDLVCSTLGMKIVIKPSSLSRMKTIFTQEIFTEQVVTAHAVRVPV 480 490 500 510 520 530 550 560 570 580 590 600 pF1KA1 TSNLSANITGFLPIHCIYQLLRSRSFTKHKVSIKDWIYRQLCETSTPLHPQLLPLIDVYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 TSNLSANITGFLPIHCIYQLLRSRSFTKHKVSIKDWIYRQLCETSTPLHPQLLPLIDVYI 540 550 560 570 580 590 610 620 630 640 650 660 pF1KA1 NSILTPASKSNPEATNQPVTEQEILNIFQGVIGGDNIRLNQRFSITAQLLVLYYILSYEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 NSILTPASKSNPEATNQPVTEQEILNIFQGVIGGDNIRLNQRFSITAQLLVLYYILSYEE 600 610 620 630 640 650 670 680 690 700 710 720 pF1KA1 ALLANTKTLAAMQRKPKSYSSSLMDQIPIKFLIRQAQGLQQELGGLHSALLRLLATNYPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 ALLANTKTLAAMQRKPKSYSSSLMDQIPIKFLIRQAQGLQQELGGLHSALLRLLATNYPH 660 670 680 690 700 710 730 740 750 760 770 780 pF1KA1 LCIVDDWICEEEITGTDALLRRMLLTNNAKNHSPKQLQEAFSAVPVNHTQVMQIIEHLTL :::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::: CCDS82 LCIVDDWICEEEITGTDALLRRMLLTNNAKNHSPKQLQEAFSAVPVNNTQVMQIIEHLTL 720 730 740 750 760 770 790 800 810 820 830 840 pF1KA1 LSASELIPYAEVLTSNMSQLLNSGVPRRILQTVNKLWMVLNTVMPRRLWVMTVNALQPSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 LSASELIPYAEVLTSNMSQLLNSGVPRRILQTVNKLWMVLNTVMPRRLWVMTVNALQPSI 780 790 800 810 820 830 850 860 870 880 890 900 pF1KA1 KFVRQQKYTQNDLMIDPLIVLRCDQRVHRCPPLMDITLHMLNGYLLASKAYLSAHLKETE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 KFVRQQKYTQNDLMIDPLIVLRCDQRVHRCPPLMDITLHMLNGYLLASKAYLSAHLKETE 840 850 860 870 880 890 910 920 930 940 950 960 pF1KA1 QDRPSQNNTIGLVGQTDAPEVTREELKNALLAAQDSAAVQILLEICLPTEEEKANGVNPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 QDRPSQNNTIGLVGQTDAPEVTREELKNALLAAQDSAAVQILLEICLPTEEEKANGVNPD 900 910 920 930 940 950 970 980 990 1000 1010 1020 pF1KA1 SLLRNVQSVITTSAPNKGMEEGEDNLLCNLREVQCLICCLLHQMYIADPNIAKLVHFQGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 SLLRNVQSVITTSAPNKGMEEGEDNLLCNLREVQCLICCLLHQMYIADPNIAKLVHFQGY 960 970 980 990 1000 1010 1030 1040 1050 1060 1070 1080 pF1KA1 PCELLPLTVAGIPSMHICLDFIPELIAQPELEKQIFAIQLLSHLCIQYALPKSLSVARLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 PCELLPLTVAGIPSMHICLDFIPELIAQPELEKQIFAIQLLSHLCIQYALPKSLSVARLA 1020 1030 1040 1050 1060 1070 1090 1100 1110 1120 1130 1140 pF1KA1 VNVMGTLLTVLTQAKRYAFFMPTLPSLVSFCRAFPPLYEDIMSLLIQIGQVCASDVATQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 VNVMGTLLTVLTQAKRYAFFMPTLPSLVSFCRAFPPLYEDIMSLLIQIGQVCASDVATQT 1080 1090 1100 1110 1120 1130 1150 1160 1170 1180 1190 1200 pF1KA1 RDIDPIITRLQQIKEKPSGWSQICKDSSYKNGSRDTGSMDPDVQLCHCIERTVIEIINMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 RDIDPIITRLQQIKEKPSGWSQICKDSSYKNGSRDTGSMDPDVQLCHCIERTVIEIINMS 1140 1150 1160 1170 1180 1190 pF1KA1 VSGI :::: CCDS82 VSGI 1204 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 19:57:33 2016 done: Thu Nov 3 19:57:34 2016 Total Scan time: 4.080 Total Display time: 0.070 Function used was FASTA [36.3.4 Apr, 2011]