FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1332, 717 aa 1>>>pF1KA1332 717 - 717 aa - 717 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.2158+/-0.000396; mu= -1.3273+/- 0.025 mean_var=298.1782+/-60.214, 0's: 0 Z-trim(121.6): 26 B-trim: 23 in 1/55 Lambda= 0.074274 statistics sampled from 38525 (38552) to 38525 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.766), E-opt: 0.2 (0.452), width: 16 Scan time: 11.770 The best scores are: opt bits E(85289) XP_006710761 (OMIM: 609109) PREDICTED: F-box only ( 717) 5013 551.1 5.7e-156 NP_061867 (OMIM: 609109) F-box only protein 42 [Ho ( 717) 5013 551.1 5.7e-156 XP_016856991 (OMIM: 609109) PREDICTED: F-box only ( 486) 3375 375.4 2.9e-103 XP_016856992 (OMIM: 609109) PREDICTED: F-box only ( 486) 3375 375.4 2.9e-103 >>XP_006710761 (OMIM: 609109) PREDICTED: F-box only prot (717 aa) initn: 5013 init1: 5013 opt: 5013 Z-score: 2921.1 bits: 551.1 E(85289): 5.7e-156 Smith-Waterman score: 5013; 100.0% identity (100.0% similar) in 717 aa overlap (1-717:1-717) 10 20 30 40 50 60 pF1KA1 MASSSDSEDDSFMAVDQEETVLEGTMDQDEEPHPVLEAEETRHNRSMSELPEEVLEYILS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MASSSDSEDDSFMAVDQEETVLEGTMDQDEEPHPVLEAEETRHNRSMSELPEEVLEYILS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 FLSPYQEHKTAALVCKQWYRLIKGVAHQCYHGFMKAVQEGNIQWESRTYPYPGTPITQRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FLSPYQEHKTAALVCKQWYRLIKGVAHQCYHGFMKAVQEGNIQWESRTYPYPGTPITQRF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 SHSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGSYPSPKAGATLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SHSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGSYPSPKAGATLV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 VYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGHSSCVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGHSSCVI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 DDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPRGGQSQIVIDDATILILG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPRGGQSQIVIDDATILILG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 GCGGPNALFKDAWLLHMHSGPWAWQPLKVENEEHGAPELWCHPACRVGQCVVVFSQAPSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GCGGPNALFKDAWLLHMHSGPWAWQPLKVENEEHGAPELWCHPACRVGQCVVVFSQAPSG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 RAPLSPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RAPLSPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQTP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 SGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDLKIGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDLKIGL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 SLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRHPPEQTNGVHTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRHPPEQTNGVHTP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 PHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGSSPGSPGSQSLSSGETVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGSSPGSPGSQSLSSGETVP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 IPRPGPAQGDGHSLPPIARRLGHHPPQSLNVGKPLYQSMNCKPMQMYVLDIKDTKEKGRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IPRPGPAQGDGHSLPPIARRLGHHPPQSLNVGKPLYQSMNCKPMQMYVLDIKDTKEKGRV 610 620 630 640 650 660 670 680 690 700 710 pF1KA1 KWKVFNSSSVVGPPETSLHTVVQGRGELIIFGGLMDKKQNVKYYPKTNALYFVRAKR ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KWKVFNSSSVVGPPETSLHTVVQGRGELIIFGGLMDKKQNVKYYPKTNALYFVRAKR 670 680 690 700 710 >>NP_061867 (OMIM: 609109) F-box only protein 42 [Homo s (717 aa) initn: 5013 init1: 5013 opt: 5013 Z-score: 2921.1 bits: 551.1 E(85289): 5.7e-156 Smith-Waterman score: 5013; 100.0% identity (100.0% similar) in 717 aa overlap (1-717:1-717) 10 20 30 40 50 60 pF1KA1 MASSSDSEDDSFMAVDQEETVLEGTMDQDEEPHPVLEAEETRHNRSMSELPEEVLEYILS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 MASSSDSEDDSFMAVDQEETVLEGTMDQDEEPHPVLEAEETRHNRSMSELPEEVLEYILS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 FLSPYQEHKTAALVCKQWYRLIKGVAHQCYHGFMKAVQEGNIQWESRTYPYPGTPITQRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 FLSPYQEHKTAALVCKQWYRLIKGVAHQCYHGFMKAVQEGNIQWESRTYPYPGTPITQRF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 SHSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGSYPSPKAGATLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 SHSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGSYPSPKAGATLV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 VYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGHSSCVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 VYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGHSSCVI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 DDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPRGGQSQIVIDDATILILG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 DDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPRGGQSQIVIDDATILILG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 GCGGPNALFKDAWLLHMHSGPWAWQPLKVENEEHGAPELWCHPACRVGQCVVVFSQAPSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 GCGGPNALFKDAWLLHMHSGPWAWQPLKVENEEHGAPELWCHPACRVGQCVVVFSQAPSG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 RAPLSPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 RAPLSPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQTP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 SGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDLKIGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 SGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDLKIGL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 SLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRHPPEQTNGVHTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 SLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRHPPEQTNGVHTP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 PHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGSSPGSPGSQSLSSGETVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 PHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGSSPGSPGSQSLSSGETVP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 IPRPGPAQGDGHSLPPIARRLGHHPPQSLNVGKPLYQSMNCKPMQMYVLDIKDTKEKGRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 IPRPGPAQGDGHSLPPIARRLGHHPPQSLNVGKPLYQSMNCKPMQMYVLDIKDTKEKGRV 610 620 630 640 650 660 670 680 690 700 710 pF1KA1 KWKVFNSSSVVGPPETSLHTVVQGRGELIIFGGLMDKKQNVKYYPKTNALYFVRAKR ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 KWKVFNSSSVVGPPETSLHTVVQGRGELIIFGGLMDKKQNVKYYPKTNALYFVRAKR 670 680 690 700 710 >>XP_016856991 (OMIM: 609109) PREDICTED: F-box only prot (486 aa) initn: 3375 init1: 3375 opt: 3375 Z-score: 1974.9 bits: 375.4 E(85289): 2.9e-103 Smith-Waterman score: 3375; 100.0% identity (100.0% similar) in 486 aa overlap (232-717:1-486) 210 220 230 240 250 260 pF1KA1 QPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGHSSCVIDDKMIVFGGSLGSRQMSNDVW :::::::::::::::::::::::::::::: XP_016 MAGHSSCVIDDKMIVFGGSLGSRQMSNDVW 10 20 30 270 280 290 300 310 320 pF1KA1 VLDLEQWAWSKPNISGPSPHPRGGQSQIVIDDATILILGGCGGPNALFKDAWLLHMHSGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLDLEQWAWSKPNISGPSPHPRGGQSQIVIDDATILILGGCGGPNALFKDAWLLHMHSGP 40 50 60 70 80 90 330 340 350 360 370 380 pF1KA1 WAWQPLKVENEEHGAPELWCHPACRVGQCVVVFSQAPSGRAPLSPSLNSRPSPISATPPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WAWQPLKVENEEHGAPELWCHPACRVGQCVVVFSQAPSGRAPLSPSLNSRPSPISATPPA 100 110 120 130 140 150 390 400 410 420 430 440 pF1KA1 LVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQTPSGSREGSLSPARGDGSPILNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQTPSGSREGSLSPARGDGSPILNG 160 170 180 190 200 210 450 460 470 480 490 500 pF1KA1 GSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDLKIGLSLAPRRGSLPDQKDLRLGSID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDLKIGLSLAPRRGSLPDQKDLRLGSID 220 230 240 250 260 270 510 520 530 540 550 560 pF1KA1 LNWDLKPASSSNPMDGMDNRTVGGSMRHPPEQTNGVHTPPHVASALAGAVSPGALRRSLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LNWDLKPASSSNPMDGMDNRTVGGSMRHPPEQTNGVHTPPHVASALAGAVSPGALRRSLE 280 290 300 310 320 330 570 580 590 600 610 620 pF1KA1 AIKAMSSKGPSASAALSPPLGSSPGSPGSQSLSSGETVPIPRPGPAQGDGHSLPPIARRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AIKAMSSKGPSASAALSPPLGSSPGSPGSQSLSSGETVPIPRPGPAQGDGHSLPPIARRL 340 350 360 370 380 390 630 640 650 660 670 680 pF1KA1 GHHPPQSLNVGKPLYQSMNCKPMQMYVLDIKDTKEKGRVKWKVFNSSSVVGPPETSLHTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GHHPPQSLNVGKPLYQSMNCKPMQMYVLDIKDTKEKGRVKWKVFNSSSVVGPPETSLHTV 400 410 420 430 440 450 690 700 710 pF1KA1 VQGRGELIIFGGLMDKKQNVKYYPKTNALYFVRAKR :::::::::::::::::::::::::::::::::::: XP_016 VQGRGELIIFGGLMDKKQNVKYYPKTNALYFVRAKR 460 470 480 >>XP_016856992 (OMIM: 609109) PREDICTED: F-box only prot (486 aa) initn: 3375 init1: 3375 opt: 3375 Z-score: 1974.9 bits: 375.4 E(85289): 2.9e-103 Smith-Waterman score: 3375; 100.0% identity (100.0% similar) in 486 aa overlap (232-717:1-486) 210 220 230 240 250 260 pF1KA1 QPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGHSSCVIDDKMIVFGGSLGSRQMSNDVW :::::::::::::::::::::::::::::: XP_016 MAGHSSCVIDDKMIVFGGSLGSRQMSNDVW 10 20 30 270 280 290 300 310 320 pF1KA1 VLDLEQWAWSKPNISGPSPHPRGGQSQIVIDDATILILGGCGGPNALFKDAWLLHMHSGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLDLEQWAWSKPNISGPSPHPRGGQSQIVIDDATILILGGCGGPNALFKDAWLLHMHSGP 40 50 60 70 80 90 330 340 350 360 370 380 pF1KA1 WAWQPLKVENEEHGAPELWCHPACRVGQCVVVFSQAPSGRAPLSPSLNSRPSPISATPPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WAWQPLKVENEEHGAPELWCHPACRVGQCVVVFSQAPSGRAPLSPSLNSRPSPISATPPA 100 110 120 130 140 150 390 400 410 420 430 440 pF1KA1 LVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQTPSGSREGSLSPARGDGSPILNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQTPSGSREGSLSPARGDGSPILNG 160 170 180 190 200 210 450 460 470 480 490 500 pF1KA1 GSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDLKIGLSLAPRRGSLPDQKDLRLGSID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDLKIGLSLAPRRGSLPDQKDLRLGSID 220 230 240 250 260 270 510 520 530 540 550 560 pF1KA1 LNWDLKPASSSNPMDGMDNRTVGGSMRHPPEQTNGVHTPPHVASALAGAVSPGALRRSLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LNWDLKPASSSNPMDGMDNRTVGGSMRHPPEQTNGVHTPPHVASALAGAVSPGALRRSLE 280 290 300 310 320 330 570 580 590 600 610 620 pF1KA1 AIKAMSSKGPSASAALSPPLGSSPGSPGSQSLSSGETVPIPRPGPAQGDGHSLPPIARRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AIKAMSSKGPSASAALSPPLGSSPGSPGSQSLSSGETVPIPRPGPAQGDGHSLPPIARRL 340 350 360 370 380 390 630 640 650 660 670 680 pF1KA1 GHHPPQSLNVGKPLYQSMNCKPMQMYVLDIKDTKEKGRVKWKVFNSSSVVGPPETSLHTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GHHPPQSLNVGKPLYQSMNCKPMQMYVLDIKDTKEKGRVKWKVFNSSSVVGPPETSLHTV 400 410 420 430 440 450 690 700 710 pF1KA1 VQGRGELIIFGGLMDKKQNVKYYPKTNALYFVRAKR :::::::::::::::::::::::::::::::::::: XP_016 VQGRGELIIFGGLMDKKQNVKYYPKTNALYFVRAKR 460 470 480 717 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 20:59:34 2016 done: Wed Nov 2 20:59:35 2016 Total Scan time: 11.770 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]