FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1333, 706 aa 1>>>pF1KA1333 706 - 706 aa - 706 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7272+/-0.000398; mu= 18.5484+/- 0.025 mean_var=90.0127+/-18.585, 0's: 0 Z-trim(113.2): 99 B-trim: 0 in 0/50 Lambda= 0.135183 statistics sampled from 22264 (22366) to 22264 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.633), E-opt: 0.2 (0.262), width: 16 Scan time: 11.030 The best scores are: opt bits E(85289) NP_060239 (OMIM: 611299) G2/M phase-specific E3 ub ( 706) 4894 965.2 0 XP_011535227 (OMIM: 611299) PREDICTED: G2/M phase- ( 706) 4894 965.2 0 NP_001295026 (OMIM: 611299) G2/M phase-specific E3 ( 660) 4551 898.3 0 XP_011535228 (OMIM: 611299) PREDICTED: G2/M phase- ( 667) 3065 608.5 2.7e-173 NP_001015877 (OMIM: 300414,301900) PHD finger prot ( 365) 295 68.1 7.1e-11 NP_115834 (OMIM: 300414,301900) PHD finger protein ( 365) 295 68.1 7.1e-11 NP_115711 (OMIM: 300414,301900) PHD finger protein ( 312) 290 67.0 1.2e-10 NP_001035534 (OMIM: 147050,600807,607796) PHD fing ( 292) 235 56.3 2e-07 NP_001035533 (OMIM: 147050,600807,607796) PHD fing ( 331) 235 56.3 2.2e-07 XP_006718902 (OMIM: 159555,605130) PREDICTED: hist (3133) 217 53.6 1.4e-05 XP_011541135 (OMIM: 159555,605130) PREDICTED: hist (3166) 217 53.6 1.4e-05 NP_005924 (OMIM: 159555,605130) histone-lysine N-m (3969) 217 53.6 1.7e-05 NP_001184033 (OMIM: 159555,605130) histone-lysine (3972) 217 53.6 1.7e-05 XP_011541133 (OMIM: 159555,605130) PREDICTED: hist (4002) 217 53.6 1.7e-05 XP_011541132 (OMIM: 159555,605130) PREDICTED: hist (4004) 217 53.6 1.7e-05 XP_011541131 (OMIM: 159555,605130) PREDICTED: hist (4005) 217 53.6 1.7e-05 XP_016883035 (OMIM: 606834) PREDICTED: histone-lys (1703) 201 50.2 7.7e-05 XP_011525863 (OMIM: 606834) PREDICTED: histone-lys (2527) 201 50.4 0.00011 XP_016883034 (OMIM: 606834) PREDICTED: histone-lys (2527) 201 50.4 0.00011 XP_011525864 (OMIM: 606834) PREDICTED: histone-lys (2628) 201 50.4 0.00011 XP_016883033 (OMIM: 606834) PREDICTED: histone-lys (2685) 201 50.4 0.00011 NP_055542 (OMIM: 606834) histone-lysine N-methyltr (2715) 201 50.4 0.00011 XP_016867979 (OMIM: 606833) PREDICTED: histone-lys (3741) 200 50.3 0.00016 XP_016867978 (OMIM: 606833) PREDICTED: histone-lys (3873) 200 50.3 0.00017 XP_011514756 (OMIM: 606833) PREDICTED: histone-lys (4678) 200 50.4 0.00019 XP_011514755 (OMIM: 606833) PREDICTED: histone-lys (4904) 200 50.4 0.0002 NP_733751 (OMIM: 606833) histone-lysine N-methyltr (4911) 200 50.4 0.0002 XP_016867977 (OMIM: 606833) PREDICTED: histone-lys (4922) 200 50.4 0.0002 XP_006716142 (OMIM: 606833) PREDICTED: histone-lys (4927) 200 50.4 0.0002 XP_005250088 (OMIM: 606833) PREDICTED: histone-lys (4928) 200 50.4 0.0002 XP_011514754 (OMIM: 606833) PREDICTED: histone-lys (4932) 200 50.4 0.0002 XP_016867976 (OMIM: 606833) PREDICTED: histone-lys (4934) 200 50.4 0.0002 XP_011514753 (OMIM: 606833) PREDICTED: histone-lys (4943) 200 50.4 0.0002 XP_016867975 (OMIM: 606833) PREDICTED: histone-lys (4954) 200 50.4 0.0002 XP_006716141 (OMIM: 606833) PREDICTED: histone-lys (4959) 200 50.4 0.0002 XP_011514758 (OMIM: 606833) PREDICTED: histone-lys (4963) 200 50.4 0.0002 XP_016867974 (OMIM: 606833) PREDICTED: histone-lys (4966) 200 50.4 0.0002 XP_011514752 (OMIM: 606833) PREDICTED: histone-lys (4967) 200 50.4 0.0002 XP_016867973 (OMIM: 606833) PREDICTED: histone-lys (4972) 200 50.4 0.0002 XP_016867971 (OMIM: 606833) PREDICTED: histone-lys (4978) 200 50.4 0.0002 XP_016867972 (OMIM: 606833) PREDICTED: histone-lys (4978) 200 50.4 0.0002 XP_005250085 (OMIM: 606833) PREDICTED: histone-lys (4979) 200 50.4 0.0002 XP_016867970 (OMIM: 606833) PREDICTED: histone-lys (4982) 200 50.4 0.0002 XP_005250084 (OMIM: 606833) PREDICTED: histone-lys (4982) 200 50.4 0.0002 XP_005250083 (OMIM: 606833) PREDICTED: histone-lys (4982) 200 50.4 0.0002 XP_006716140 (OMIM: 606833) PREDICTED: histone-lys (4982) 200 50.4 0.0002 XP_005250082 (OMIM: 606833) PREDICTED: histone-lys (4983) 200 50.4 0.0002 XP_016867969 (OMIM: 606833) PREDICTED: histone-lys (4983) 200 50.4 0.0002 XP_005261779 (OMIM: 603107) PREDICTED: transcripti (1960) 186 47.4 0.00066 XP_006724376 (OMIM: 603107) PREDICTED: transcripti (1960) 186 47.4 0.00066 >>NP_060239 (OMIM: 611299) G2/M phase-specific E3 ubiqui (706 aa) initn: 4894 init1: 4894 opt: 4894 Z-score: 5159.7 bits: 965.2 E(85289): 0 Smith-Waterman score: 4894; 100.0% identity (100.0% similar) in 706 aa overlap (1-706:1-706) 10 20 30 40 50 60 pF1KA1 MNESKPGDSQNLACVFCRKHDDCPNKYGEKKTKEKWNLTVHYYCLLMSSGIWQRGKEEEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 MNESKPGDSQNLACVFCRKHDDCPNKYGEKKTKEKWNLTVHYYCLLMSSGIWQRGKEEEG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 VYGFLIEDIRKEVNRASKLKCCVCKKNGASIGCVAPRCKRSYHFPCGLQRECIFQFTGNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 VYGFLIEDIRKEVNRASKLKCCVCKKNGASIGCVAPRCKRSYHFPCGLQRECIFQFTGNF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 ASFCWDHRPVQIITSNNYRESLPCTICLEFIEPIPSYNILRSPCCKNAWFHRDCLQVQAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 ASFCWDHRPVQIITSNNYRESLPCTICLEFIEPIPSYNILRSPCCKNAWFHRDCLQVQAI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 NAGVFFFRCTICNNSDIFQKEMLRMGIHIPEKDASWELEENAYQELLQHYERCDVRRCRC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 NAGVFFFRCTICNNSDIFQKEMLRMGIHIPEKDASWELEENAYQELLQHYERCDVRRCRC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 KEGRDYNAPDSKWEIKRCQCCGSSGTHLACSSLRSWEQNWECLECRGIIYNSGEFQKAKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 KEGRDYNAPDSKWEIKRCQCCGSSGTHLACSSLRSWEQNWECLECRGIIYNSGEFQKAKK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 HVLPNSNNVGITDCLLEESSPKLPRQSPGSQSKDLLRQGSKFRRNVSTLLIELGFQIKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 HVLPNSNNVGITDCLLEESSPKLPRQSPGSQSKDLLRQGSKFRRNVSTLLIELGFQIKKK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 TKRLYINKANIWNSALDAFRNRNFNPSYAIEVAYVIENDNFGSEHPGSKQEFLSLLMQHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 TKRLYINKANIWNSALDAFRNRNFNPSYAIEVAYVIENDNFGSEHPGSKQEFLSLLMQHL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 ENSSLFEGSLSKNLSLNSQALKENLYYEAGKMLAISLVHGGPSPGFFSKTLFNCLVYGPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 ENSSLFEGSLSKNLSLNSQALKENLYYEAGKMLAISLVHGGPSPGFFSKTLFNCLVYGPE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 NTQPILDDVSDFDVAQIIIRINTATTVADLKSIINECYNYLELIGCLRLITTLSDKYMLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 NTQPILDDVSDFDVAQIIIRINTATTVADLKSIINECYNYLELIGCLRLITTLSDKYMLV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 KDILGYHVIQRVHTPFESFKQGLKTLGVLEKIQAYPEAFCSILCHKPESLSAKILSELFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 KDILGYHVIQRVHTPFESFKQGLKTLGVLEKIQAYPEAFCSILCHKPESLSAKILSELFT 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 VHTLPDVKALGFWNSYLQAVEDGKSTTTMEDILIFATGCSSIPPAGFKPTPSIECLHVDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 VHTLPDVKALGFWNSYLQAVEDGKSTTTMEDILIFATGCSSIPPAGFKPTPSIECLHVDF 610 620 630 640 650 660 670 680 690 700 pF1KA1 PVGNKCNNCLAIPITNTYKEFQENMDFTIRNTLRLEKEESSHYIGH :::::::::::::::::::::::::::::::::::::::::::::: NP_060 PVGNKCNNCLAIPITNTYKEFQENMDFTIRNTLRLEKEESSHYIGH 670 680 690 700 >>XP_011535227 (OMIM: 611299) PREDICTED: G2/M phase-spec (706 aa) initn: 4894 init1: 4894 opt: 4894 Z-score: 5159.7 bits: 965.2 E(85289): 0 Smith-Waterman score: 4894; 100.0% identity (100.0% similar) in 706 aa overlap (1-706:1-706) 10 20 30 40 50 60 pF1KA1 MNESKPGDSQNLACVFCRKHDDCPNKYGEKKTKEKWNLTVHYYCLLMSSGIWQRGKEEEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MNESKPGDSQNLACVFCRKHDDCPNKYGEKKTKEKWNLTVHYYCLLMSSGIWQRGKEEEG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 VYGFLIEDIRKEVNRASKLKCCVCKKNGASIGCVAPRCKRSYHFPCGLQRECIFQFTGNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VYGFLIEDIRKEVNRASKLKCCVCKKNGASIGCVAPRCKRSYHFPCGLQRECIFQFTGNF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 ASFCWDHRPVQIITSNNYRESLPCTICLEFIEPIPSYNILRSPCCKNAWFHRDCLQVQAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASFCWDHRPVQIITSNNYRESLPCTICLEFIEPIPSYNILRSPCCKNAWFHRDCLQVQAI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 NAGVFFFRCTICNNSDIFQKEMLRMGIHIPEKDASWELEENAYQELLQHYERCDVRRCRC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NAGVFFFRCTICNNSDIFQKEMLRMGIHIPEKDASWELEENAYQELLQHYERCDVRRCRC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 KEGRDYNAPDSKWEIKRCQCCGSSGTHLACSSLRSWEQNWECLECRGIIYNSGEFQKAKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KEGRDYNAPDSKWEIKRCQCCGSSGTHLACSSLRSWEQNWECLECRGIIYNSGEFQKAKK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 HVLPNSNNVGITDCLLEESSPKLPRQSPGSQSKDLLRQGSKFRRNVSTLLIELGFQIKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HVLPNSNNVGITDCLLEESSPKLPRQSPGSQSKDLLRQGSKFRRNVSTLLIELGFQIKKK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 TKRLYINKANIWNSALDAFRNRNFNPSYAIEVAYVIENDNFGSEHPGSKQEFLSLLMQHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TKRLYINKANIWNSALDAFRNRNFNPSYAIEVAYVIENDNFGSEHPGSKQEFLSLLMQHL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 ENSSLFEGSLSKNLSLNSQALKENLYYEAGKMLAISLVHGGPSPGFFSKTLFNCLVYGPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ENSSLFEGSLSKNLSLNSQALKENLYYEAGKMLAISLVHGGPSPGFFSKTLFNCLVYGPE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 NTQPILDDVSDFDVAQIIIRINTATTVADLKSIINECYNYLELIGCLRLITTLSDKYMLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NTQPILDDVSDFDVAQIIIRINTATTVADLKSIINECYNYLELIGCLRLITTLSDKYMLV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 KDILGYHVIQRVHTPFESFKQGLKTLGVLEKIQAYPEAFCSILCHKPESLSAKILSELFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KDILGYHVIQRVHTPFESFKQGLKTLGVLEKIQAYPEAFCSILCHKPESLSAKILSELFT 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 VHTLPDVKALGFWNSYLQAVEDGKSTTTMEDILIFATGCSSIPPAGFKPTPSIECLHVDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VHTLPDVKALGFWNSYLQAVEDGKSTTTMEDILIFATGCSSIPPAGFKPTPSIECLHVDF 610 620 630 640 650 660 670 680 690 700 pF1KA1 PVGNKCNNCLAIPITNTYKEFQENMDFTIRNTLRLEKEESSHYIGH :::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVGNKCNNCLAIPITNTYKEFQENMDFTIRNTLRLEKEESSHYIGH 670 680 690 700 >>NP_001295026 (OMIM: 611299) G2/M phase-specific E3 ubi (660 aa) initn: 4551 init1: 4551 opt: 4551 Z-score: 4798.5 bits: 898.3 E(85289): 0 Smith-Waterman score: 4551; 100.0% identity (100.0% similar) in 660 aa overlap (47-706:1-660) 20 30 40 50 60 70 pF1KA1 CRKHDDCPNKYGEKKTKEKWNLTVHYYCLLMSSGIWQRGKEEEGVYGFLIEDIRKEVNRA :::::::::::::::::::::::::::::: NP_001 MSSGIWQRGKEEEGVYGFLIEDIRKEVNRA 10 20 30 80 90 100 110 120 130 pF1KA1 SKLKCCVCKKNGASIGCVAPRCKRSYHFPCGLQRECIFQFTGNFASFCWDHRPVQIITSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SKLKCCVCKKNGASIGCVAPRCKRSYHFPCGLQRECIFQFTGNFASFCWDHRPVQIITSN 40 50 60 70 80 90 140 150 160 170 180 190 pF1KA1 NYRESLPCTICLEFIEPIPSYNILRSPCCKNAWFHRDCLQVQAINAGVFFFRCTICNNSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NYRESLPCTICLEFIEPIPSYNILRSPCCKNAWFHRDCLQVQAINAGVFFFRCTICNNSD 100 110 120 130 140 150 200 210 220 230 240 250 pF1KA1 IFQKEMLRMGIHIPEKDASWELEENAYQELLQHYERCDVRRCRCKEGRDYNAPDSKWEIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IFQKEMLRMGIHIPEKDASWELEENAYQELLQHYERCDVRRCRCKEGRDYNAPDSKWEIK 160 170 180 190 200 210 260 270 280 290 300 310 pF1KA1 RCQCCGSSGTHLACSSLRSWEQNWECLECRGIIYNSGEFQKAKKHVLPNSNNVGITDCLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RCQCCGSSGTHLACSSLRSWEQNWECLECRGIIYNSGEFQKAKKHVLPNSNNVGITDCLL 220 230 240 250 260 270 320 330 340 350 360 370 pF1KA1 EESSPKLPRQSPGSQSKDLLRQGSKFRRNVSTLLIELGFQIKKKTKRLYINKANIWNSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EESSPKLPRQSPGSQSKDLLRQGSKFRRNVSTLLIELGFQIKKKTKRLYINKANIWNSAL 280 290 300 310 320 330 380 390 400 410 420 430 pF1KA1 DAFRNRNFNPSYAIEVAYVIENDNFGSEHPGSKQEFLSLLMQHLENSSLFEGSLSKNLSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DAFRNRNFNPSYAIEVAYVIENDNFGSEHPGSKQEFLSLLMQHLENSSLFEGSLSKNLSL 340 350 360 370 380 390 440 450 460 470 480 490 pF1KA1 NSQALKENLYYEAGKMLAISLVHGGPSPGFFSKTLFNCLVYGPENTQPILDDVSDFDVAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NSQALKENLYYEAGKMLAISLVHGGPSPGFFSKTLFNCLVYGPENTQPILDDVSDFDVAQ 400 410 420 430 440 450 500 510 520 530 540 550 pF1KA1 IIIRINTATTVADLKSIINECYNYLELIGCLRLITTLSDKYMLVKDILGYHVIQRVHTPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IIIRINTATTVADLKSIINECYNYLELIGCLRLITTLSDKYMLVKDILGYHVIQRVHTPF 460 470 480 490 500 510 560 570 580 590 600 610 pF1KA1 ESFKQGLKTLGVLEKIQAYPEAFCSILCHKPESLSAKILSELFTVHTLPDVKALGFWNSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ESFKQGLKTLGVLEKIQAYPEAFCSILCHKPESLSAKILSELFTVHTLPDVKALGFWNSY 520 530 540 550 560 570 620 630 640 650 660 670 pF1KA1 LQAVEDGKSTTTMEDILIFATGCSSIPPAGFKPTPSIECLHVDFPVGNKCNNCLAIPITN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQAVEDGKSTTTMEDILIFATGCSSIPPAGFKPTPSIECLHVDFPVGNKCNNCLAIPITN 580 590 600 610 620 630 680 690 700 pF1KA1 TYKEFQENMDFTIRNTLRLEKEESSHYIGH :::::::::::::::::::::::::::::: NP_001 TYKEFQENMDFTIRNTLRLEKEESSHYIGH 640 650 660 >>XP_011535228 (OMIM: 611299) PREDICTED: G2/M phase-spec (667 aa) initn: 3061 init1: 3061 opt: 3065 Z-score: 3232.2 bits: 608.5 E(85289): 2.7e-173 Smith-Waterman score: 4513; 94.3% identity (94.5% similar) in 706 aa overlap (1-706:1-667) 10 20 30 40 50 60 pF1KA1 MNESKPGDSQNLACVFCRKHDDCPNKYGEKKTKEKWNLTVHYYCLLMSSGIWQRGKEEEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MNESKPGDSQNLACVFCRKHDDCPNKYGEKKTKEKWNLTVHYYCLLMSSGIWQRGKEEEG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 VYGFLIEDIRKEVNRASKLKCCVCKKNGASIGCVAPRCKRSYHFPCGLQRECIFQFTGNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VYGFLIEDIRKEVNRASKLKCCVCKKNGASIGCVAPRCKRSYHFPCGLQRECIFQFTGNF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 ASFCWDHRPVQIITSNNYRESLPCTICLEFIEPIPSYNILRSPCCKNAWFHRDCLQVQAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASFCWDHRPVQIITSNNYRESLPCTICLEFIEPIPSYNILRSPCCKNAWFHRDCLQVQAI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 NAGVFFFRCTICNNSDIFQKEMLRMGIHIPEKDASWELEENAYQELLQHYERCDVRRCRC ::::::::::::::::::::::::::::::: XP_011 NAGVFFFRCTICNNSDIFQKEMLRMGIHIPE----------------------------- 190 200 210 250 260 270 280 290 300 pF1KA1 KEGRDYNAPDSKWEIKRCQCCGSSGTHLACSSLRSWEQNWECLECRGIIYNSGEFQKAKK .::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ----------NKWEIKRCQCCGSSGTHLACSSLRSWEQNWECLECRGIIYNSGEFQKAKK 220 230 240 250 260 310 320 330 340 350 360 pF1KA1 HVLPNSNNVGITDCLLEESSPKLPRQSPGSQSKDLLRQGSKFRRNVSTLLIELGFQIKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HVLPNSNNVGITDCLLEESSPKLPRQSPGSQSKDLLRQGSKFRRNVSTLLIELGFQIKKK 270 280 290 300 310 320 370 380 390 400 410 420 pF1KA1 TKRLYINKANIWNSALDAFRNRNFNPSYAIEVAYVIENDNFGSEHPGSKQEFLSLLMQHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TKRLYINKANIWNSALDAFRNRNFNPSYAIEVAYVIENDNFGSEHPGSKQEFLSLLMQHL 330 340 350 360 370 380 430 440 450 460 470 480 pF1KA1 ENSSLFEGSLSKNLSLNSQALKENLYYEAGKMLAISLVHGGPSPGFFSKTLFNCLVYGPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ENSSLFEGSLSKNLSLNSQALKENLYYEAGKMLAISLVHGGPSPGFFSKTLFNCLVYGPE 390 400 410 420 430 440 490 500 510 520 530 540 pF1KA1 NTQPILDDVSDFDVAQIIIRINTATTVADLKSIINECYNYLELIGCLRLITTLSDKYMLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NTQPILDDVSDFDVAQIIIRINTATTVADLKSIINECYNYLELIGCLRLITTLSDKYMLV 450 460 470 480 490 500 550 560 570 580 590 600 pF1KA1 KDILGYHVIQRVHTPFESFKQGLKTLGVLEKIQAYPEAFCSILCHKPESLSAKILSELFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KDILGYHVIQRVHTPFESFKQGLKTLGVLEKIQAYPEAFCSILCHKPESLSAKILSELFT 510 520 530 540 550 560 610 620 630 640 650 660 pF1KA1 VHTLPDVKALGFWNSYLQAVEDGKSTTTMEDILIFATGCSSIPPAGFKPTPSIECLHVDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VHTLPDVKALGFWNSYLQAVEDGKSTTTMEDILIFATGCSSIPPAGFKPTPSIECLHVDF 570 580 590 600 610 620 670 680 690 700 pF1KA1 PVGNKCNNCLAIPITNTYKEFQENMDFTIRNTLRLEKEESSHYIGH :::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVGNKCNNCLAIPITNTYKEFQENMDFTIRNTLRLEKEESSHYIGH 630 640 650 660 >>NP_001015877 (OMIM: 300414,301900) PHD finger protein (365 aa) initn: 265 init1: 237 opt: 295 Z-score: 316.2 bits: 68.1 E(85289): 7.1e-11 Smith-Waterman score: 295; 31.4% identity (65.4% similar) in 156 aa overlap (3-153:6-153) 10 20 30 40 50 pF1KA1 MNESKPGDSQNLACVFCRKHDDCPNKYGEKKTKEKWNLTVHYYCLLMSSGIWQRGKE :.: : ... : ::... : .. :. .:. ....:. :.:.::.. . .. NP_001 MSSSVEQKKGPTRQRKCGFCKSNRD--KECGQLLISENQKVAAHHKCMLFSSALVSSHSD 10 20 30 40 50 60 70 80 90 100 110 pF1KA1 EEGVYGFLIEDIRKEVNRASKLKCCVCKKNGASIGCVAPRCKRSYHFPCGLQ-----REC .:.. :: :::..::..:..:: : .:. ::.::: . :.:.::. :.:. :: NP_001 NESLGGFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREK 60 70 80 90 100 110 120 130 140 150 160 170 pF1KA1 IFQFTGNFASFCWDHRPVQIITSNNYRESLPCTICLEFIEPIPSYNILRSPCCKNAWFHR : : . .: :. :..: . .: .. . .:: NP_001 PSQ--GIYMVYCRKHKK----TAHNSEADLEESFNEHELEPSSPKSKKKSRKGRPRKTNF 120 130 140 150 160 170 180 190 200 210 220 230 pF1KA1 DCLQVQAINAGVFFFRCTICNNSDIFQKEMLRMGIHIPEKDASWELEENAYQELLQHYER NP_001 KGLSEDTRSTSSHGTDEMESSSYRDRSPHRSSPSDTRPKCGFCHVGEEENEARGKLHIFN 180 190 200 210 220 230 >-- initn: 194 init1: 130 opt: 251 Z-score: 269.8 bits: 59.5 E(85289): 2.7e-08 Smith-Waterman score: 251; 28.5% identity (62.3% similar) in 130 aa overlap (2-127:201-329) 10 20 30 pF1KA1 MNESKPGDSQNLACVFCRKHDDCPNKYGEKK ..:.:.:.. : ::. .. . :. . NP_001 NFKGLSEDTRSTSSHGTDEMESSSYRDRSPHRSSPSDTRP-KCGFCHVGEEENEARGKLH 180 190 200 210 220 40 50 60 70 80 90 pF1KA1 TKEKWNLTVHYYCLLMSSGIWQRGKEEEGVYG-FLIEDIRKEVNRASKLKCCVCKKNGAS . . ..:: :.:.::: : .. .: : :. . .:..:....:: .:.. ::. NP_001 IFNAKKAAAHYKCMLFSSGTVQLTTTSRAEFGDFDIKTVLQEIKRGKRMKCTLCSQPGAT 230 240 250 260 270 280 100 110 120 130 140 pF1KA1 IGCVAPRCKRSYHFPCGLQRECIF---QFTGNFASFCWDHRPVQIITSNNYRESLPCTIC ::: : ..::. ::.: . . . : . .: .: NP_001 IGCEIKACVKTYHYHCGVQDKAKYIENMSRGIYKLYCKNHSGNDERDEEDEERESKSRGK 290 300 310 320 330 340 150 160 170 180 190 200 pF1KA1 LEFIEPIPSYNILRSPCCKNAWFHRDCLQVQAINAGVFFFRCTICNNSDIFQKEMLRMGI NP_001 VEIDQQQLTQQQLNGN 350 360 >>NP_115834 (OMIM: 300414,301900) PHD finger protein 6 i (365 aa) initn: 265 init1: 237 opt: 295 Z-score: 316.2 bits: 68.1 E(85289): 7.1e-11 Smith-Waterman score: 295; 31.4% identity (65.4% similar) in 156 aa overlap (3-153:6-153) 10 20 30 40 50 pF1KA1 MNESKPGDSQNLACVFCRKHDDCPNKYGEKKTKEKWNLTVHYYCLLMSSGIWQRGKE :.: : ... : ::... : .. :. .:. ....:. :.:.::.. . .. NP_115 MSSSVEQKKGPTRQRKCGFCKSNRD--KECGQLLISENQKVAAHHKCMLFSSALVSSHSD 10 20 30 40 50 60 70 80 90 100 110 pF1KA1 EEGVYGFLIEDIRKEVNRASKLKCCVCKKNGASIGCVAPRCKRSYHFPCGLQ-----REC .:.. :: :::..::..:..:: : .:. ::.::: . :.:.::. :.:. :: NP_115 NESLGGFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREK 60 70 80 90 100 110 120 130 140 150 160 170 pF1KA1 IFQFTGNFASFCWDHRPVQIITSNNYRESLPCTICLEFIEPIPSYNILRSPCCKNAWFHR : : . .: :. :..: . .: .. . .:: NP_115 PSQ--GIYMVYCRKHKK----TAHNSEADLEESFNEHELEPSSPKSKKKSRKGRPRKTNF 120 130 140 150 160 170 180 190 200 210 220 230 pF1KA1 DCLQVQAINAGVFFFRCTICNNSDIFQKEMLRMGIHIPEKDASWELEENAYQELLQHYER NP_115 KGLSEDTRSTSSHGTDEMESSSYRDRSPHRSSPSDTRPKCGFCHVGEEENEARGKLHIFN 180 190 200 210 220 230 >-- initn: 194 init1: 130 opt: 251 Z-score: 269.8 bits: 59.5 E(85289): 2.7e-08 Smith-Waterman score: 251; 28.5% identity (62.3% similar) in 130 aa overlap (2-127:201-329) 10 20 30 pF1KA1 MNESKPGDSQNLACVFCRKHDDCPNKYGEKK ..:.:.:.. : ::. .. . :. . NP_115 NFKGLSEDTRSTSSHGTDEMESSSYRDRSPHRSSPSDTRP-KCGFCHVGEEENEARGKLH 180 190 200 210 220 40 50 60 70 80 90 pF1KA1 TKEKWNLTVHYYCLLMSSGIWQRGKEEEGVYG-FLIEDIRKEVNRASKLKCCVCKKNGAS . . ..:: :.:.::: : .. .: : :. . .:..:....:: .:.. ::. NP_115 IFNAKKAAAHYKCMLFSSGTVQLTTTSRAEFGDFDIKTVLQEIKRGKRMKCTLCSQPGAT 230 240 250 260 270 280 100 110 120 130 140 pF1KA1 IGCVAPRCKRSYHFPCGLQRECIF---QFTGNFASFCWDHRPVQIITSNNYRESLPCTIC ::: : ..::. ::.: . . . : . .: .: NP_115 IGCEIKACVKTYHYHCGVQDKAKYIENMSRGIYKLYCKNHSGNDERDEEDEERESKSRGK 290 300 310 320 330 340 150 160 170 180 190 200 pF1KA1 LEFIEPIPSYNILRSPCCKNAWFHRDCLQVQAINAGVFFFRCTICNNSDIFQKEMLRMGI NP_115 VEIDQQQLTQQQLNGN 350 360 >>NP_115711 (OMIM: 300414,301900) PHD finger protein 6 i (312 aa) initn: 299 init1: 237 opt: 290 Z-score: 311.9 bits: 67.0 E(85289): 1.2e-10 Smith-Waterman score: 290; 33.6% identity (67.9% similar) in 131 aa overlap (3-128:6-132) 10 20 30 40 50 pF1KA1 MNESKPGDSQNLACVFCRKHDDCPNKYGEKKTKEKWNLTVHYYCLLMSSGIWQRGKE :.: : ... : ::... : .. :. .:. ....:. :.:.::.. . .. NP_115 MSSSVEQKKGPTRQRKCGFCKSNRD--KECGQLLISENQKVAAHHKCMLFSSALVSSHSD 10 20 30 40 50 60 70 80 90 100 110 pF1KA1 EEGVYGFLIEDIRKEVNRASKLKCCVCKKNGASIGCVAPRCKRSYHFPCGLQ-----REC .:.. :: :::..::..:..:: : .:. ::.::: . :.:.::. :.:. :: NP_115 NESLGGFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREK 60 70 80 90 100 110 120 130 140 150 160 170 pF1KA1 IFQFTGNFASFCWDHRPVQIITSNNYRESLPCTICLEFIEPIPSYNILRSPCCKNAWFHR : : . .: :. NP_115 PSQ--GIYMVYCRKHKKTAHNSEAADLEESFNEHELEPSSPKSKKKSRKGRPRKTNFKGL 120 130 140 150 160 170 >>NP_001035534 (OMIM: 147050,600807,607796) PHD finger p (292 aa) initn: 214 init1: 159 opt: 235 Z-score: 254.3 bits: 56.3 E(85289): 2e-07 Smith-Waterman score: 235; 24.7% identity (52.9% similar) in 223 aa overlap (23-233:9-229) 10 20 30 40 50 pF1KA1 MNESKPGDSQNLACVFCRKHDDCPN--KYGEKKTKEKWNLTVHYYCLLMSSGIWQRGKEE ::. .:. .. :...: :::.:::. . .. NP_001 MEKRTCALCPKDVEYNVLYFAQSENIAAHENCLLYSSGLVECEDQD 10 20 30 40 60 70 80 90 100 110 pF1KA1 --EGVYGFLIEDIRKEVNRASKLKCCVCKKNGASIGCVAPRCKRSYHFPCGLQRECIFQ- . .: .:...::..:. :::: :.: ::..:: :...::: :. . . . : NP_001 PLNPDRSFDVESVKKEIQRGRKLKCKFCHKRGATVGCDLKNCNKNYHFFCAKKDDAVPQS 50 60 70 80 90 100 120 130 140 150 160 170 pF1KA1 --FTGNFASFCWDHRPVQIITSNNYRESLPCTICLEFIEPIPSYNILRSPCCKNAWFHRD : . .: .: ::... .. . .:. . .. : : :. NP_001 DGVRGIYKLLCQQHAQFPIIAQSAKFSGVKRKRGRK--KPLSGNHVQPPETMKCNTFIRQ 110 120 130 140 150 160 180 190 200 210 220 pF1KA1 CLQVQA--INAGV---FFFRCTICNNSDIFQKEMLRMGIHIPEKDASWELEENAYQELLQ . .. .: : :. .: . . . .:.: :::: . :. :.:. . NP_001 VKEEHGRHTDATVKVPFLKKCKEAGLLNYLLEEILDKVHSIPEKLMDETTSESDYEEIGS 170 180 190 200 210 220 230 240 250 260 270 280 pF1KA1 HYERCDVRRCRCKEGRDYNAPDSKWEIKRCQCCGSSGTHLACSSLRSWEQNWECLECRGI : NP_001 ALFDCRLFEDTFVNFQAAIEKKIHASQQRWQQLKEEIELLQDLKQTLCSFQENRDLMSSS 230 240 250 260 270 280 >>NP_001035533 (OMIM: 147050,600807,607796) PHD finger p (331 aa) initn: 214 init1: 159 opt: 235 Z-score: 253.6 bits: 56.3 E(85289): 2.2e-07 Smith-Waterman score: 235; 24.7% identity (52.9% similar) in 223 aa overlap (23-233:48-268) 10 20 30 40 50 pF1KA1 MNESKPGDSQNLACVFCRKHDDCPN--KYGEKKTKEKWNLTVHYYCLLMSSG ::. .:. .. :...: :::.::: NP_001 PEARPAQEALLLPTGVFQVAEKMEKRTCALCPKDVEYNVLYFAQSENIAAHENCLLYSSG 20 30 40 50 60 70 60 70 80 90 100 pF1KA1 IWQRGKEE--EGVYGFLIEDIRKEVNRASKLKCCVCKKNGASIGCVAPRCKRSYHFPCGL . . .. . .: .:...::..:. :::: :.: ::..:: :...::: :. NP_001 LVECEDQDPLNPDRSFDVESVKKEIQRGRKLKCKFCHKRGATVGCDLKNCNKNYHFFCAK 80 90 100 110 120 130 110 120 130 140 150 160 pF1KA1 QRECIFQ---FTGNFASFCWDHRPVQIITSNNYRESLPCTICLEFIEPIPSYNILRSPCC . . . : : . .: .: ::... .. . .:. . .. NP_001 KDDAVPQSDGVRGIYKLLCQQHAQFPIIAQSAKFSGVKRKRGRK--KPLSGNHVQPPETM 140 150 160 170 180 190 170 180 190 200 210 220 pF1KA1 KNAWFHRDCLQVQA--INAGV---FFFRCTICNNSDIFQKEMLRMGIHIPEKDASWELEE : : :. . .. .: : :. .: . . . .:.: :::: . : NP_001 KCNTFIRQVKEEHGRHTDATVKVPFLKKCKEAGLLNYLLEEILDKVHSIPEKLMDETTSE 200 210 220 230 240 250 230 240 250 260 270 280 pF1KA1 NAYQELLQHYERCDVRRCRCKEGRDYNAPDSKWEIKRCQCCGSSGTHLACSSLRSWEQNW . :.:. . : NP_001 SDYEEIGSALFDCRLFEDTFVNFQAAIEKKIHASQQRWQQLKEEIELLQDLKQTLCSFQE 260 270 280 290 300 310 >>XP_006718902 (OMIM: 159555,605130) PREDICTED: histone- (3133 aa) initn: 107 init1: 107 opt: 217 Z-score: 221.0 bits: 53.6 E(85289): 1.4e-05 Smith-Waterman score: 219; 25.9% identity (55.4% similar) in 139 aa overlap (6-138:1029-1155) 10 20 30 pF1KA1 MNESKPGDSQNLACVFCRKH-DDCPNKYGE--KKT :: .: :..: . :: : :. XP_006 PDSPTPLHPPTPPILSTDRSREDSPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIG 1000 1010 1020 1030 1040 1050 40 50 60 70 80 90 pF1KA1 KEKWNLTVHYYCLLMSSGIWQRGKEEEGVYGFLIEDIRKEVNRASKLKCCVCKKNGASIG ...:. : : : :. ... ...: ..... : :...:.: :.: ::..: XP_006 QNEWT---HVNCALWSAEVFE---DDDGS----LKNVHMAVIRGKQLRCEFCQKPGATVG 1060 1070 1080 1090 1100 100 110 120 130 140 pF1KA1 CVAPRCKRSYHFPCGLQRECIFQFTGNFASFCWDHRPV---QIITSNNYRESLPCTICLE : : .::: :. ..:.: . .: :: . ... :.. XP_006 CCLTSCTSNYHFMCSRAKNCVF--LDDKKVYCQRHRDLIKGEVVPENGFEVFRRVFVDFE 1110 1120 1130 1140 1150 1160 150 160 170 180 190 200 pF1KA1 FIEPIPSYNILRSPCCKNAWFHRDCLQVQAINAGVFFFRCTICNNSDIFQKEMLRMGIHI XP_006 GISLRRKFLNGLEPENIHMMIGSMTIDCLGILNDLSDCEDKLFPIGYQCSRVYWSTTDAR 1170 1180 1190 1200 1210 1220 706 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 21:00:16 2016 done: Wed Nov 2 21:00:18 2016 Total Scan time: 11.030 Total Display time: 0.100 Function used was FASTA [36.3.4 Apr, 2011]