FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1370, 1076 aa 1>>>pF1KA1370 1076 - 1076 aa - 1076 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.3159+/-0.00114; mu= 11.7753+/- 0.069 mean_var=97.8980+/-19.148, 0's: 0 Z-trim(104.5): 35 B-trim: 0 in 0/49 Lambda= 0.129625 statistics sampled from 7934 (7954) to 7934 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.604), E-opt: 0.2 (0.244), width: 16 Scan time: 4.060 The best scores are: opt bits E(32554) CCDS45263.1 FAM214A gene_id:56204|Hs108|chr15 (1076) 7179 1353.8 0 CCDS66773.1 FAM214A gene_id:56204|Hs108|chr15 (1083) 7141 1346.7 0 CCDS6578.1 FAM214B gene_id:80256|Hs108|chr9 ( 538) 836 167.5 6.9e-41 >>CCDS45263.1 FAM214A gene_id:56204|Hs108|chr15 (1076 aa) initn: 7179 init1: 7179 opt: 7179 Z-score: 7253.1 bits: 1353.8 E(32554): 0 Smith-Waterman score: 7179; 99.9% identity (100.0% similar) in 1076 aa overlap (1-1076:1-1076) 10 20 30 40 50 60 pF1KA1 MKPDRDTLDEYFEYDAEEFLVSLALLITEGRTPECSVKGRTESFHCPPAQSCYPVTTKHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 MKPDRDTLDEYFEYDAEEFLVSLALLITEGRTPECSVKGRTESFHCPPAQSCYPVTTKHE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 CSDKLAQCRQARRTRSEVTLLWKNNLPIMVEMMLLPDCCYSDDGPTTEGIDLNDPAIKQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 CSDKLAQCRQARRTRSEVTLLWKNNLPIMVEMMLLPDCCYSDDGPTTEGIDLNDPAIKQD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 ALLLERWILEPVPRQNGDRFIEEKTLLLAVRSFVFFSQLSAWLSVSHGAIPRNILYRISA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 ALLLERWILEPVPRQNGDRFIEEKTLLLAVRSFVFFSQLSAWLSVSHGAIPRNILYRISA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 ADVDLQWNFSQTPIEHVFPVPNVSHNVALKVSVQSLPRQSNYPVLTCSIHTNIGLYEKRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 ADVDLQWNFSQTPIEHVFPVPNVSHNVALKVSVQSLPRQSNYPVLTCSIHTNIGLYEKRI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 QQHKLKTHQHHNPNEAEQCGTNSSQRLCSKQTWTMAPESVLHAKSGPSPEYTAAVKNIKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 QQHKLKTHQHHNPNEAEQCGTNSSQRLCSKQTWTMAPESVLHAKSGPSPEYTAAVKNIKL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 YPGTGSKSDHGTSQANILGFSGIGDIKSQETSVRTLKSFSMVDSSISNRQSFWQSAGETN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 YPGTGSKSDHGTSQANILGFSGIGDIKSQETSVRTLKSFSMVDSSISNRQSFWQSAGETN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 PLIGSLIQERQEIIARIAQHLIHCDPSTSHVSGRPFNTQESSSLHSKLFRVSQENENVGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 PLIGSLIQERQEIIARIAQHLIHCDPSTSHVSGRPFNTQESSSLHSKLFRVSQENENVGK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 GKEAFSMTFGSPEFSSPEDTNEGKIRLKPETPRSETCISNDFYSHMPVGETNPLIGSLLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 GKEAFSMTFGSPEFSSPEDTNEGKIRLKPETPRSETCISNDFYSHMPVGETNPLIGSLLQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 ERQDVIARIAQHLEHIDPTASHIPRQSFNMHDSSSVASKVFRSSYEDKNLLKKNKDESSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 ERQDVIARIAQHLEHIDPTASHIPRQSFNMHDSSSVASKVFRSSYEDKNLLKKNKDESSV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 SISHTKCSLLGDISDGKNLIPNKCFTSFKNNSKEKCSLKHQTRNQCQNNPSEIIQSTYQE :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: CCDS45 SISHTKCSLLGDISDGKNLVPNKCFTSFKNNSKEKCSLKHQTRNQCQNNPSEIIQSTYQE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 TQNKSSSLSTSSILSQHKENNLDLTSRFKEQEMSNGIDKQYSNCTTIDKQICTNKYKEKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 TQNKSSSLSTSSILSQHKENNLDLTSRFKEQEMSNGIDKQYSNCTTIDKQICTNKYKEKI 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 INENYNPKFFGNLQSDDSKKNDSKIKVTVLEMSEYLNKYESMSSNKDSKRPKTCEQNTQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 INENYNPKFFGNLQSDDSKKNDSKIKVTVLEMSEYLNKYESMSSNKDSKRPKTCEQNTQL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 NSIENYLNKDNEGFKCKKSDQLKNEQDKQEDPTNEKSQNYSQRRSIKDCLSTCEQPKNTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 NSIENYLNKDNEGFKCKKSDQLKNEQDKQEDPTNEKSQNYSQRRSIKDCLSTCEQPKNTE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 VLRTTLKHSNVWRKHNFHSLDGTSTRAFHPQTGLPLLSSPVPQRKTQSGCFDLDSSLLHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 VLRTTLKHSNVWRKHNFHSLDGTSTRAFHPQTGLPLLSSPVPQRKTQSGCFDLDSSLLHL 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 KSFSSRSPRPCLNIEDDPDIHEKPFLSSSAPPITSLSLLGNFEESVLNYRFDPLGIVDGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 KSFSSRSPRPCLNIEDDPDIHEKPFLSSSAPPITSLSLLGNFEESVLNYRFDPLGIVDGF 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 TAEVGASGAFCPTHLTLPVEVSFYSVSDDNAPSPYMGVITLESLGKRGYRVPPSGTIQVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 TAEVGASGAFCPTHLTLPVEVSFYSVSDDNAPSPYMGVITLESLGKRGYRVPPSGTIQVT 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 LFNPNKTVVKMFVVIYDLRDMPANHQTFLRQRTFSVPVKQEVKRSVNKENIRHTEERLLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 LFNPNKTVVKMFVVIYDLRDMPANHQTFLRQRTFSVPVKQEVKRSVNKENIRHTEERLLR 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 pF1KA1 YLIHLRFQSSKSGKIYLHRDVRLLFSRKSMEVDSGAAYELKSYTESPTNPQFSPRC :::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 YLIHLRFQSSKSGKIYLHRDVRLLFSRKSMEVDSGAAYELKSYTESPTNPQFSPRC 1030 1040 1050 1060 1070 >>CCDS66773.1 FAM214A gene_id:56204|Hs108|chr15 (1083 aa) initn: 7141 init1: 7141 opt: 7141 Z-score: 7214.7 bits: 1346.7 E(32554): 0 Smith-Waterman score: 7141; 99.9% identity (100.0% similar) in 1071 aa overlap (6-1076:13-1083) 10 20 30 40 50 pF1KA1 MKPDRDTLDEYFEYDAEEFLVSLALLITEGRTPECSVKGRTESFHCPPAQSCY :::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 MVFSGNKGLHREDTLDEYFEYDAEEFLVSLALLITEGRTPECSVKGRTESFHCPPAQSCY 10 20 30 40 50 60 60 70 80 90 100 110 pF1KA1 PVTTKHECSDKLAQCRQARRTRSEVTLLWKNNLPIMVEMMLLPDCCYSDDGPTTEGIDLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 PVTTKHECSDKLAQCRQARRTRSEVTLLWKNNLPIMVEMMLLPDCCYSDDGPTTEGIDLN 70 80 90 100 110 120 120 130 140 150 160 170 pF1KA1 DPAIKQDALLLERWILEPVPRQNGDRFIEEKTLLLAVRSFVFFSQLSAWLSVSHGAIPRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 DPAIKQDALLLERWILEPVPRQNGDRFIEEKTLLLAVRSFVFFSQLSAWLSVSHGAIPRN 130 140 150 160 170 180 180 190 200 210 220 230 pF1KA1 ILYRISAADVDLQWNFSQTPIEHVFPVPNVSHNVALKVSVQSLPRQSNYPVLTCSIHTNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 ILYRISAADVDLQWNFSQTPIEHVFPVPNVSHNVALKVSVQSLPRQSNYPVLTCSIHTNI 190 200 210 220 230 240 240 250 260 270 280 290 pF1KA1 GLYEKRIQQHKLKTHQHHNPNEAEQCGTNSSQRLCSKQTWTMAPESVLHAKSGPSPEYTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 GLYEKRIQQHKLKTHQHHNPNEAEQCGTNSSQRLCSKQTWTMAPESVLHAKSGPSPEYTA 250 260 270 280 290 300 300 310 320 330 340 350 pF1KA1 AVKNIKLYPGTGSKSDHGTSQANILGFSGIGDIKSQETSVRTLKSFSMVDSSISNRQSFW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 AVKNIKLYPGTGSKSDHGTSQANILGFSGIGDIKSQETSVRTLKSFSMVDSSISNRQSFW 310 320 330 340 350 360 360 370 380 390 400 410 pF1KA1 QSAGETNPLIGSLIQERQEIIARIAQHLIHCDPSTSHVSGRPFNTQESSSLHSKLFRVSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 QSAGETNPLIGSLIQERQEIIARIAQHLIHCDPSTSHVSGRPFNTQESSSLHSKLFRVSQ 370 380 390 400 410 420 420 430 440 450 460 470 pF1KA1 ENENVGKGKEAFSMTFGSPEFSSPEDTNEGKIRLKPETPRSETCISNDFYSHMPVGETNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 ENENVGKGKEAFSMTFGSPEFSSPEDTNEGKIRLKPETPRSETCISNDFYSHMPVGETNP 430 440 450 460 470 480 480 490 500 510 520 530 pF1KA1 LIGSLLQERQDVIARIAQHLEHIDPTASHIPRQSFNMHDSSSVASKVFRSSYEDKNLLKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 LIGSLLQERQDVIARIAQHLEHIDPTASHIPRQSFNMHDSSSVASKVFRSSYEDKNLLKK 490 500 510 520 530 540 540 550 560 570 580 590 pF1KA1 NKDESSVSISHTKCSLLGDISDGKNLIPNKCFTSFKNNSKEKCSLKHQTRNQCQNNPSEI ::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::: CCDS66 NKDESSVSISHTKCSLLGDISDGKNLVPNKCFTSFKNNSKEKCSLKHQTRNQCQNNPSEI 550 560 570 580 590 600 600 610 620 630 640 650 pF1KA1 IQSTYQETQNKSSSLSTSSILSQHKENNLDLTSRFKEQEMSNGIDKQYSNCTTIDKQICT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 IQSTYQETQNKSSSLSTSSILSQHKENNLDLTSRFKEQEMSNGIDKQYSNCTTIDKQICT 610 620 630 640 650 660 660 670 680 690 700 710 pF1KA1 NKYKEKIINENYNPKFFGNLQSDDSKKNDSKIKVTVLEMSEYLNKYESMSSNKDSKRPKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 NKYKEKIINENYNPKFFGNLQSDDSKKNDSKIKVTVLEMSEYLNKYESMSSNKDSKRPKT 670 680 690 700 710 720 720 730 740 750 760 770 pF1KA1 CEQNTQLNSIENYLNKDNEGFKCKKSDQLKNEQDKQEDPTNEKSQNYSQRRSIKDCLSTC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 CEQNTQLNSIENYLNKDNEGFKCKKSDQLKNEQDKQEDPTNEKSQNYSQRRSIKDCLSTC 730 740 750 760 770 780 780 790 800 810 820 830 pF1KA1 EQPKNTEVLRTTLKHSNVWRKHNFHSLDGTSTRAFHPQTGLPLLSSPVPQRKTQSGCFDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 EQPKNTEVLRTTLKHSNVWRKHNFHSLDGTSTRAFHPQTGLPLLSSPVPQRKTQSGCFDL 790 800 810 820 830 840 840 850 860 870 880 890 pF1KA1 DSSLLHLKSFSSRSPRPCLNIEDDPDIHEKPFLSSSAPPITSLSLLGNFEESVLNYRFDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 DSSLLHLKSFSSRSPRPCLNIEDDPDIHEKPFLSSSAPPITSLSLLGNFEESVLNYRFDP 850 860 870 880 890 900 900 910 920 930 940 950 pF1KA1 LGIVDGFTAEVGASGAFCPTHLTLPVEVSFYSVSDDNAPSPYMGVITLESLGKRGYRVPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 LGIVDGFTAEVGASGAFCPTHLTLPVEVSFYSVSDDNAPSPYMGVITLESLGKRGYRVPP 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KA1 SGTIQVTLFNPNKTVVKMFVVIYDLRDMPANHQTFLRQRTFSVPVKQEVKRSVNKENIRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 SGTIQVTLFNPNKTVVKMFVVIYDLRDMPANHQTFLRQRTFSVPVKQEVKRSVNKENIRH 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KA1 TEERLLRYLIHLRFQSSKSGKIYLHRDVRLLFSRKSMEVDSGAAYELKSYTESPTNPQFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 TEERLLRYLIHLRFQSSKSGKIYLHRDVRLLFSRKSMEVDSGAAYELKSYTESPTNPQFS 1030 1040 1050 1060 1070 1080 pF1KA1 PRC ::: CCDS66 PRC >>CCDS6578.1 FAM214B gene_id:80256|Hs108|chr9 (538 aa) initn: 847 init1: 570 opt: 836 Z-score: 847.5 bits: 167.5 E(32554): 6.9e-41 Smith-Waterman score: 836; 54.2% identity (76.9% similar) in 225 aa overlap (850-1074:320-536) 820 830 840 850 860 870 pF1KA1 PVPQRKTQSGCFDLDSSLLHLKSFSSRSPRPCLNIEDDPDIHEKPFLSSSAPPITSLSLL : ... : . : : : .: .:: CCDS65 LPGPKEPVLDPTDCGPMGRRLKGARRLKLSPLRSLRKGPGLLSPPSASPVPTPAVSRTLL 290 300 310 320 330 340 880 890 900 910 920 930 pF1KA1 GNFEESVLNYRFDPLGIVDGFTAEVGASGAFCPTHLTLPVEVSFYSVSDDNAPSPYMGVI ::::::.: :: : : ..:::::.::::..:: :.:::: :.:..::..:::.:..:.. CCDS65 GNFEESLLRGRFAPSGHIEGFTAEIGASGSYCPQHVTLPVTVTFFDVSEQNAPAPFLGIV 350 360 370 380 390 400 940 950 960 970 980 990 pF1KA1 TLESLGKRGYRVPPSGTIQVTLFNPNKTVVKMFVVIYDLRDMPANHQTFLRQRTFSVPVK :. ::..:: :: ::.::::::::.::::::.: .:. :::: :.::::.: : ::: CCDS65 DLNPLGRKGYSVPKVGTVQVTLFNPNQTVVKMFLVTFDFSDMPAAHMTFLRHRLFLVPVG 410 420 430 440 450 460 1000 1010 1020 1030 1040 1050 pF1KA1 QEVKRSVNKENIRHTEERLLRYLIHLRFQSSKSGKIYLHRDVRLLFSRKSMEVDSGAAYE .: .. : : ::: ::.::::.::.::.. :: :.::::::.:.:.:.: :: CCDS65 EE-----GNANPTH---RLLCYLLHLRFRSSRSGRLSLHGDIRLLFSRRSLELDTGLPYE 470 480 490 500 510 520 1060 1070 pF1KA1 LKSYTESPTNPQFSPRC :.. ::.: ::..:: CCDS65 LQAVTEAPHNPRYSPLP 530 1076 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 01:30:53 2016 done: Fri Nov 4 01:30:54 2016 Total Scan time: 4.060 Total Display time: 0.130 Function used was FASTA [36.3.4 Apr, 2011]