FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1408, 1272 aa 1>>>pF1KA1408 1272 - 1272 aa - 1272 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 12.8172+/-0.000621; mu= -12.8581+/- 0.039 mean_var=507.0263+/-102.678, 0's: 0 Z-trim(119.3): 10 B-trim: 1105 in 1/55 Lambda= 0.056959 statistics sampled from 33235 (33245) to 33235 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.697), E-opt: 0.2 (0.39), width: 16 Scan time: 18.520 The best scores are: opt bits E(85289) NP_056357 (OMIM: 605529) regulator of nonsense tra (1272) 8439 709.8 2.9e-203 NP_542166 (OMIM: 605529) regulator of nonsense tra (1272) 8439 709.8 2.9e-203 XP_016871523 (OMIM: 605529) PREDICTED: regulator o ( 869) 5825 494.9 1e-138 XP_011517751 (OMIM: 605529) PREDICTED: regulator o ( 718) 4517 387.3 2e-106 >>NP_056357 (OMIM: 605529) regulator of nonsense transcr (1272 aa) initn: 8439 init1: 8439 opt: 8439 Z-score: 3770.2 bits: 709.8 E(85289): 2.9e-203 Smith-Waterman score: 8439; 100.0% identity (100.0% similar) in 1272 aa overlap (1-1272:1-1272) 10 20 30 40 50 60 pF1KA1 MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 EDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 EDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 MKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 MKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 ITEQQRDSLSHDFNGLNLSKYIAEAVASIVEAKLKISDVNCAVHLCSLFHQRYADFAPSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 ITEQQRDSLSHDFNGLNLSKYIAEAVASIVEAKLKISDVNCAVHLCSLFHQRYADFAPSL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 LQVWKKHFEARKEEKTPNITKLRTDLRFIAELTIVGIFTDKEGLSLIYEQLKNIINADRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LQVWKKHFEARKEEKTPNITKLRTDLRFIAELTIVGIFTDKEGLSLIYEQLKNIINADRE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 SHTHVSVVISFCRHCGDDIAGLVPRKVKSAAEKFNLSFPPSEIISPEKQQPFQNLLKEYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 SHTHVSVVISFCRHCGDDIAGLVPRKVKSAAEKFNLSFPPSEIISPEKQQPFQNLLKEYF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 TSLTKHLKRDHRELQNTERQNRRILHSKGELSEDRHKQYEEFAMSYQKLLANSQSLADLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 TSLTKHLKRDHRELQNTERQNRRILHSKGELSEDRHKQYEEFAMSYQKLLANSQSLADLL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 DENMPDLPQDKPTPEEHGPGIDIFTPGKPGEYDLEGGIWEDEDARNFYENLIDLKAFVPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 DENMPDLPQDKPTPEEHGPGIDIFTPGKPGEYDLEGGIWEDEDARNFYENLIDLKAFVPA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 ILFKDNEKSCQNKESNKDDTKEAKESKENKEVSSPDDLELELENLEINDDTLELEGGDEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 ILFKDNEKSCQNKESNKDDTKEAKESKENKEVSSPDDLELELENLEINDDTLELEGGDEA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 EDLTKKLLDEQEQEDEEASTGSHLKLIVDAFLQQLPNCVNRDLIDKAAMDFCMNMNTKAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 EDLTKKLLDEQEQEDEEASTGSHLKLIVDAFLQQLPNCVNRDLIDKAAMDFCMNMNTKAN 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 RKKLVRALFIVPRQRLDLLPFYARLVATLHPCMSDVAEDLCSMLRGDFRFHVRKKDQINI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 RKKLVRALFIVPRQRLDLLPFYARLVATLHPCMSDVAEDLCSMLRGDFRFHVRKKDQINI 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 ETKNKTVRFIGELTKFKMFTKNDTLHCLKMLLSDFSHHHIEMACTLLETCGRFLFRSPES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 ETKNKTVRFIGELTKFKMFTKNDTLHCLKMLLSDFSHHHIEMACTLLETCGRFLFRSPES 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 HLRTSVLLEQMMRKKQAMHLDARYVTMVENAYYYCNPPPAEKTVKKKRPPLQEYVRKLLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 HLRTSVLLEQMMRKKQAMHLDARYVTMVENAYYYCNPPPAEKTVKKKRPPLQEYVRKLLY 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 KDLSKVTTEKVLRQMRKLPWQDQEVKDYVICCMINIWNVKYNSIHCVANLLAGLVLYQED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 KDLSKVTTEKVLRQMRKLPWQDQEVKDYVICCMINIWNVKYNSIHCVANLLAGLVLYQED 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 VGIHVVDGVLEDIRLGMEVNQPKFNQRRISSAKFLGELYNYRMVESAVIFRTLYSFTSFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 VGIHVVDGVLEDIRLGMEVNQPKFNQRRISSAKFLGELYNYRMVESAVIFRTLYSFTSFG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 VNPDGSPSSLDPPEHLFRIRLVCTILDTCGQYFDRGSSKRKLDCFLVYFQRYVWWKKSLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 VNPDGSPSSLDPPEHLFRIRLVCTILDTCGQYFDRGSSKRKLDCFLVYFQRYVWWKKSLE 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 VWTKDHPFPIDIDYMISDTLELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKDSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 VWTKDHPFPIDIDYMISDTLELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKDSK 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA1 DSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 DSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLT 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA1 DSNKENETDEENTEVMIKGGGLKHVPCVEDEDFIQALDKMMLENLQQRSGESVKVHQLDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 DSNKENETDEENTEVMIKGGGLKHVPCVEDEDFIQALDKMMLENLQQRSGESVKVHQLDV 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA1 AIPLHLKSQLRKGPPLGGGEGEAESADTMPFVMLTRKGNKQQFKILNVPMSSQLAANHWN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 AIPLHLKSQLRKGPPLGGGEGEAESADTMPFVMLTRKGNKQQFKILNVPMSSQLAANHWN 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA1 QQQAEQEERMRMKKLTLDINERQEQEDYQEMLQSLAQRPAPANTNRERRPRYQHPKGAPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 QQQAEQEERMRMKKLTLDINERQEQEDYQEMLQSLAQRPAPANTNRERRPRYQHPKGAPN 1210 1220 1230 1240 1250 1260 1270 pF1KA1 ADLIFKTGGRRR :::::::::::: NP_056 ADLIFKTGGRRR 1270 >>NP_542166 (OMIM: 605529) regulator of nonsense transcr (1272 aa) initn: 8439 init1: 8439 opt: 8439 Z-score: 3770.2 bits: 709.8 E(85289): 2.9e-203 Smith-Waterman score: 8439; 100.0% identity (100.0% similar) in 1272 aa overlap (1-1272:1-1272) 10 20 30 40 50 60 pF1KA1 MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 EDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 EDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 MKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 MKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 ITEQQRDSLSHDFNGLNLSKYIAEAVASIVEAKLKISDVNCAVHLCSLFHQRYADFAPSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 ITEQQRDSLSHDFNGLNLSKYIAEAVASIVEAKLKISDVNCAVHLCSLFHQRYADFAPSL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 LQVWKKHFEARKEEKTPNITKLRTDLRFIAELTIVGIFTDKEGLSLIYEQLKNIINADRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 LQVWKKHFEARKEEKTPNITKLRTDLRFIAELTIVGIFTDKEGLSLIYEQLKNIINADRE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 SHTHVSVVISFCRHCGDDIAGLVPRKVKSAAEKFNLSFPPSEIISPEKQQPFQNLLKEYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 SHTHVSVVISFCRHCGDDIAGLVPRKVKSAAEKFNLSFPPSEIISPEKQQPFQNLLKEYF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 TSLTKHLKRDHRELQNTERQNRRILHSKGELSEDRHKQYEEFAMSYQKLLANSQSLADLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 TSLTKHLKRDHRELQNTERQNRRILHSKGELSEDRHKQYEEFAMSYQKLLANSQSLADLL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 DENMPDLPQDKPTPEEHGPGIDIFTPGKPGEYDLEGGIWEDEDARNFYENLIDLKAFVPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 DENMPDLPQDKPTPEEHGPGIDIFTPGKPGEYDLEGGIWEDEDARNFYENLIDLKAFVPA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 ILFKDNEKSCQNKESNKDDTKEAKESKENKEVSSPDDLELELENLEINDDTLELEGGDEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 ILFKDNEKSCQNKESNKDDTKEAKESKENKEVSSPDDLELELENLEINDDTLELEGGDEA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 EDLTKKLLDEQEQEDEEASTGSHLKLIVDAFLQQLPNCVNRDLIDKAAMDFCMNMNTKAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 EDLTKKLLDEQEQEDEEASTGSHLKLIVDAFLQQLPNCVNRDLIDKAAMDFCMNMNTKAN 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 RKKLVRALFIVPRQRLDLLPFYARLVATLHPCMSDVAEDLCSMLRGDFRFHVRKKDQINI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 RKKLVRALFIVPRQRLDLLPFYARLVATLHPCMSDVAEDLCSMLRGDFRFHVRKKDQINI 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 ETKNKTVRFIGELTKFKMFTKNDTLHCLKMLLSDFSHHHIEMACTLLETCGRFLFRSPES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 ETKNKTVRFIGELTKFKMFTKNDTLHCLKMLLSDFSHHHIEMACTLLETCGRFLFRSPES 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 HLRTSVLLEQMMRKKQAMHLDARYVTMVENAYYYCNPPPAEKTVKKKRPPLQEYVRKLLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 HLRTSVLLEQMMRKKQAMHLDARYVTMVENAYYYCNPPPAEKTVKKKRPPLQEYVRKLLY 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 KDLSKVTTEKVLRQMRKLPWQDQEVKDYVICCMINIWNVKYNSIHCVANLLAGLVLYQED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 KDLSKVTTEKVLRQMRKLPWQDQEVKDYVICCMINIWNVKYNSIHCVANLLAGLVLYQED 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 VGIHVVDGVLEDIRLGMEVNQPKFNQRRISSAKFLGELYNYRMVESAVIFRTLYSFTSFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 VGIHVVDGVLEDIRLGMEVNQPKFNQRRISSAKFLGELYNYRMVESAVIFRTLYSFTSFG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 VNPDGSPSSLDPPEHLFRIRLVCTILDTCGQYFDRGSSKRKLDCFLVYFQRYVWWKKSLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 VNPDGSPSSLDPPEHLFRIRLVCTILDTCGQYFDRGSSKRKLDCFLVYFQRYVWWKKSLE 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 VWTKDHPFPIDIDYMISDTLELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKDSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 VWTKDHPFPIDIDYMISDTLELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKDSK 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA1 DSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 DSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLT 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA1 DSNKENETDEENTEVMIKGGGLKHVPCVEDEDFIQALDKMMLENLQQRSGESVKVHQLDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 DSNKENETDEENTEVMIKGGGLKHVPCVEDEDFIQALDKMMLENLQQRSGESVKVHQLDV 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA1 AIPLHLKSQLRKGPPLGGGEGEAESADTMPFVMLTRKGNKQQFKILNVPMSSQLAANHWN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 AIPLHLKSQLRKGPPLGGGEGEAESADTMPFVMLTRKGNKQQFKILNVPMSSQLAANHWN 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA1 QQQAEQEERMRMKKLTLDINERQEQEDYQEMLQSLAQRPAPANTNRERRPRYQHPKGAPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 QQQAEQEERMRMKKLTLDINERQEQEDYQEMLQSLAQRPAPANTNRERRPRYQHPKGAPN 1210 1220 1230 1240 1250 1260 1270 pF1KA1 ADLIFKTGGRRR :::::::::::: NP_542 ADLIFKTGGRRR 1270 >>XP_016871523 (OMIM: 605529) PREDICTED: regulator of no (869 aa) initn: 5825 init1: 5825 opt: 5825 Z-score: 2611.4 bits: 494.9 E(85289): 1e-138 Smith-Waterman score: 5825; 100.0% identity (100.0% similar) in 869 aa overlap (404-1272:1-869) 380 390 400 410 420 430 pF1KA1 LQNTERQNRRILHSKGELSEDRHKQYEEFAMSYQKLLANSQSLADLLDENMPDLPQDKPT :::::::::::::::::::::::::::::: XP_016 MSYQKLLANSQSLADLLDENMPDLPQDKPT 10 20 30 440 450 460 470 480 490 pF1KA1 PEEHGPGIDIFTPGKPGEYDLEGGIWEDEDARNFYENLIDLKAFVPAILFKDNEKSCQNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PEEHGPGIDIFTPGKPGEYDLEGGIWEDEDARNFYENLIDLKAFVPAILFKDNEKSCQNK 40 50 60 70 80 90 500 510 520 530 540 550 pF1KA1 ESNKDDTKEAKESKENKEVSSPDDLELELENLEINDDTLELEGGDEAEDLTKKLLDEQEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESNKDDTKEAKESKENKEVSSPDDLELELENLEINDDTLELEGGDEAEDLTKKLLDEQEQ 100 110 120 130 140 150 560 570 580 590 600 610 pF1KA1 EDEEASTGSHLKLIVDAFLQQLPNCVNRDLIDKAAMDFCMNMNTKANRKKLVRALFIVPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDEEASTGSHLKLIVDAFLQQLPNCVNRDLIDKAAMDFCMNMNTKANRKKLVRALFIVPR 160 170 180 190 200 210 620 630 640 650 660 670 pF1KA1 QRLDLLPFYARLVATLHPCMSDVAEDLCSMLRGDFRFHVRKKDQINIETKNKTVRFIGEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QRLDLLPFYARLVATLHPCMSDVAEDLCSMLRGDFRFHVRKKDQINIETKNKTVRFIGEL 220 230 240 250 260 270 680 690 700 710 720 730 pF1KA1 TKFKMFTKNDTLHCLKMLLSDFSHHHIEMACTLLETCGRFLFRSPESHLRTSVLLEQMMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TKFKMFTKNDTLHCLKMLLSDFSHHHIEMACTLLETCGRFLFRSPESHLRTSVLLEQMMR 280 290 300 310 320 330 740 750 760 770 780 790 pF1KA1 KKQAMHLDARYVTMVENAYYYCNPPPAEKTVKKKRPPLQEYVRKLLYKDLSKVTTEKVLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKQAMHLDARYVTMVENAYYYCNPPPAEKTVKKKRPPLQEYVRKLLYKDLSKVTTEKVLR 340 350 360 370 380 390 800 810 820 830 840 850 pF1KA1 QMRKLPWQDQEVKDYVICCMINIWNVKYNSIHCVANLLAGLVLYQEDVGIHVVDGVLEDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QMRKLPWQDQEVKDYVICCMINIWNVKYNSIHCVANLLAGLVLYQEDVGIHVVDGVLEDI 400 410 420 430 440 450 860 870 880 890 900 910 pF1KA1 RLGMEVNQPKFNQRRISSAKFLGELYNYRMVESAVIFRTLYSFTSFGVNPDGSPSSLDPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLGMEVNQPKFNQRRISSAKFLGELYNYRMVESAVIFRTLYSFTSFGVNPDGSPSSLDPP 460 470 480 490 500 510 920 930 940 950 960 970 pF1KA1 EHLFRIRLVCTILDTCGQYFDRGSSKRKLDCFLVYFQRYVWWKKSLEVWTKDHPFPIDID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EHLFRIRLVCTILDTCGQYFDRGSSKRKLDCFLVYFQRYVWWKKSLEVWTKDHPFPIDID 520 530 540 550 560 570 980 990 1000 1010 1020 1030 pF1KA1 YMISDTLELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGENLEEDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YMISDTLELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGENLEEDE 580 590 600 610 620 630 1040 1050 1060 1070 1080 1090 pF1KA1 EEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENT 640 650 660 670 680 690 1100 1110 1120 1130 1140 1150 pF1KA1 EVMIKGGGLKHVPCVEDEDFIQALDKMMLENLQQRSGESVKVHQLDVAIPLHLKSQLRKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EVMIKGGGLKHVPCVEDEDFIQALDKMMLENLQQRSGESVKVHQLDVAIPLHLKSQLRKG 700 710 720 730 740 750 1160 1170 1180 1190 1200 1210 pF1KA1 PPLGGGEGEAESADTMPFVMLTRKGNKQQFKILNVPMSSQLAANHWNQQQAEQEERMRMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPLGGGEGEAESADTMPFVMLTRKGNKQQFKILNVPMSSQLAANHWNQQQAEQEERMRMK 760 770 780 790 800 810 1220 1230 1240 1250 1260 1270 pF1KA1 KLTLDINERQEQEDYQEMLQSLAQRPAPANTNRERRPRYQHPKGAPNADLIFKTGGRRR ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLTLDINERQEQEDYQEMLQSLAQRPAPANTNRERRPRYQHPKGAPNADLIFKTGGRRR 820 830 840 850 860 >>XP_011517751 (OMIM: 605529) PREDICTED: regulator of no (718 aa) initn: 4517 init1: 4517 opt: 4517 Z-score: 2031.6 bits: 387.3 E(85289): 2e-106 Smith-Waterman score: 4517; 100.0% identity (100.0% similar) in 689 aa overlap (1-689:1-689) 10 20 30 40 50 60 pF1KA1 MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 EDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 MKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 ITEQQRDSLSHDFNGLNLSKYIAEAVASIVEAKLKISDVNCAVHLCSLFHQRYADFAPSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ITEQQRDSLSHDFNGLNLSKYIAEAVASIVEAKLKISDVNCAVHLCSLFHQRYADFAPSL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 LQVWKKHFEARKEEKTPNITKLRTDLRFIAELTIVGIFTDKEGLSLIYEQLKNIINADRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQVWKKHFEARKEEKTPNITKLRTDLRFIAELTIVGIFTDKEGLSLIYEQLKNIINADRE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 SHTHVSVVISFCRHCGDDIAGLVPRKVKSAAEKFNLSFPPSEIISPEKQQPFQNLLKEYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SHTHVSVVISFCRHCGDDIAGLVPRKVKSAAEKFNLSFPPSEIISPEKQQPFQNLLKEYF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 TSLTKHLKRDHRELQNTERQNRRILHSKGELSEDRHKQYEEFAMSYQKLLANSQSLADLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSLTKHLKRDHRELQNTERQNRRILHSKGELSEDRHKQYEEFAMSYQKLLANSQSLADLL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 DENMPDLPQDKPTPEEHGPGIDIFTPGKPGEYDLEGGIWEDEDARNFYENLIDLKAFVPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DENMPDLPQDKPTPEEHGPGIDIFTPGKPGEYDLEGGIWEDEDARNFYENLIDLKAFVPA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 ILFKDNEKSCQNKESNKDDTKEAKESKENKEVSSPDDLELELENLEINDDTLELEGGDEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILFKDNEKSCQNKESNKDDTKEAKESKENKEVSSPDDLELELENLEINDDTLELEGGDEA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 EDLTKKLLDEQEQEDEEASTGSHLKLIVDAFLQQLPNCVNRDLIDKAAMDFCMNMNTKAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EDLTKKLLDEQEQEDEEASTGSHLKLIVDAFLQQLPNCVNRDLIDKAAMDFCMNMNTKAN 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 RKKLVRALFIVPRQRLDLLPFYARLVATLHPCMSDVAEDLCSMLRGDFRFHVRKKDQINI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RKKLVRALFIVPRQRLDLLPFYARLVATLHPCMSDVAEDLCSMLRGDFRFHVRKKDQINI 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 ETKNKTVRFIGELTKFKMFTKNDTLHCLKMLLSDFSHHHIEMACTLLETCGRFLFRSPES ::::::::::::::::::::::::::::: XP_011 ETKNKTVRFIGELTKFKMFTKNDTLHCLKKIGNPKHFWSQAFQIRDTSPVARNGRQLG 670 680 690 700 710 1272 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 01:33:35 2016 done: Fri Nov 4 01:33:38 2016 Total Scan time: 18.520 Total Display time: 0.150 Function used was FASTA [36.3.4 Apr, 2011]