FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1419, 2432 aa 1>>>pF1KA1419 2432 - 2432 aa - 2432 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 16.7128+/-0.000489; mu= -31.5443+/- 0.030 mean_var=472.5049+/-96.553, 0's: 0 Z-trim(120.4): 93 B-trim: 66 in 1/59 Lambda= 0.059003 statistics sampled from 35444 (35537) to 35444 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.708), E-opt: 0.2 (0.417), width: 16 Scan time: 28.160 The best scores are: opt bits E(85289) NP_892009 (OMIM: 607026) neuron navigator 2 isofor (2432) 15842 1364.7 0 NP_660093 (OMIM: 607026) neuron navigator 2 isofor (2429) 15808 1361.8 0 NP_001104488 (OMIM: 607026) neuron navigator 2 iso (2365) 15228 1312.4 0 XP_011518754 (OMIM: 607026) PREDICTED: neuron navi (2365) 15228 1312.4 0 XP_006718428 (OMIM: 607026) PREDICTED: neuron navi (2455) 14148 1220.5 0 XP_011518748 (OMIM: 607026) PREDICTED: neuron navi (2452) 14114 1217.6 0 XP_011518749 (OMIM: 607026) PREDICTED: neuron navi (2451) 13098 1131.1 0 XP_006718427 (OMIM: 607026) PREDICTED: neuron navi (2465) 10459 906.5 0 XP_016874011 (OMIM: 607026) PREDICTED: neuron navi (2401) 9879 857.1 0 XP_011518753 (OMIM: 607026) PREDICTED: neuron navi (2395) 9868 856.2 0 XP_016874012 (OMIM: 607026) PREDICTED: neuron navi (2343) 8765 762.3 1.6e-218 XP_016874013 (OMIM: 607026) PREDICTED: neuron navi (2343) 8765 762.3 1.6e-218 XP_006718429 (OMIM: 607026) PREDICTED: neuron navi (2416) 8765 762.3 1.7e-218 XP_016874009 (OMIM: 607026) PREDICTED: neuron navi (2424) 8765 762.3 1.7e-218 XP_011518750 (OMIM: 607026) PREDICTED: neuron navi (2445) 8765 762.3 1.7e-218 XP_011518746 (OMIM: 607026) PREDICTED: neuron navi (2485) 8765 762.3 1.7e-218 NP_001231892 (OMIM: 607026) neuron navigator 2 iso (2488) 8765 762.3 1.7e-218 XP_016874014 (OMIM: 607026) PREDICTED: neuron navi (2143) 8296 722.4 1.6e-206 XP_011518747 (OMIM: 607026) PREDICTED: neuron navi (2466) 7836 683.2 1.1e-194 XP_011518751 (OMIM: 607026) PREDICTED: neuron navi (2430) 7789 679.2 1.7e-193 XP_016874010 (OMIM: 607026) PREDICTED: neuron navi (2415) 7746 675.5 2.2e-192 XP_011518752 (OMIM: 607026) PREDICTED: neuron navi (2418) 7746 675.5 2.2e-192 XP_006718431 (OMIM: 607026) PREDICTED: neuron navi (1493) 6307 553.0 1e-155 NP_001104489 (OMIM: 607026) neuron navigator 2 iso (1493) 6307 553.0 1e-155 XP_005253271 (OMIM: 607026) PREDICTED: neuron navi (1481) 6231 546.6 9e-154 XP_011518756 (OMIM: 607026) PREDICTED: neuron navi (1394) 6198 543.8 5.9e-153 XP_006718430 (OMIM: 607026) PREDICTED: neuron navi (1551) 5465 481.4 4e-134 XP_016874015 (OMIM: 607026) PREDICTED: neuron navi (1582) 5455 480.5 7.3e-134 XP_011518755 (OMIM: 607026) PREDICTED: neuron navi (1464) 5445 479.7 1.2e-133 XP_006718432 (OMIM: 607026) PREDICTED: neuron navi (1464) 5445 479.7 1.2e-133 XP_016875655 (OMIM: 611629) PREDICTED: neuron navi (2328) 5423 477.8 7.1e-133 NP_001019554 (OMIM: 611629) neuron navigator 3 iso (2385) 5423 477.8 7.3e-133 XP_016875656 (OMIM: 611629) PREDICTED: neuron navi (2305) 5405 476.3 2e-132 XP_016875660 (OMIM: 611629) PREDICTED: neuron navi (1885) 4995 441.4 5.3e-122 XP_016875653 (OMIM: 611629) PREDICTED: neuron navi (2378) 4454 395.3 4.9e-108 NP_055718 (OMIM: 611629) neuron navigator 3 isofor (2363) 4425 392.9 2.7e-107 XP_005269272 (OMIM: 611629) PREDICTED: neuron navi (2356) 4370 388.2 6.9e-106 XP_011537243 (OMIM: 611629) PREDICTED: neuron navi (2342) 4337 385.4 4.8e-105 XP_016875664 (OMIM: 611629) PREDICTED: neuron navi (1700) 4284 380.8 8e-104 XP_011537242 (OMIM: 611629) PREDICTED: neuron navi (2349) 4286 381.0 9.8e-104 XP_016875661 (OMIM: 611629) PREDICTED: neuron navi (1842) 4280 380.5 1.1e-103 XP_011537246 (OMIM: 611629) PREDICTED: neuron navi (2186) 4258 378.6 4.7e-103 XP_016875659 (OMIM: 611629) PREDICTED: neuron navi (2179) 4198 373.5 1.6e-101 XP_016875654 (OMIM: 611629) PREDICTED: neuron navi (2364) 3052 276.0 4.1e-72 XP_016875662 (OMIM: 611629) PREDICTED: neuron navi (1722) 2925 265.2 5.4e-69 XP_016875657 (OMIM: 611629) PREDICTED: neuron navi (2222) 2925 265.2 6.9e-69 XP_016875663 (OMIM: 611629) PREDICTED: neuron navi (1708) 2903 263.3 2e-68 XP_016875658 (OMIM: 611629) PREDICTED: neuron navi (2208) 2903 263.3 2.5e-68 XP_016858241 (OMIM: 611628) PREDICTED: neuron navi (1475) 2491 228.2 6.1e-58 XP_011508401 (OMIM: 611628) PREDICTED: neuron navi (1866) 2491 228.2 7.7e-58 >>NP_892009 (OMIM: 607026) neuron navigator 2 isoform 1 (2432 aa) initn: 15842 init1: 15842 opt: 15842 Z-score: 7299.4 bits: 1364.7 E(85289): 0 Smith-Waterman score: 15842; 100.0% identity (100.0% similar) in 2432 aa overlap (1-2432:1-2432) 10 20 30 40 50 60 pF1KA1 MPAILVASKMKSGLPKPVHSAAPILHVPPARAGPQPCYLKLGSKVEVSKTTYPSQIPLKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_892 MPAILVASKMKSGLPKPVHSAAPILHVPPARAGPQPCYLKLGSKVEVSKTTYPSQIPLKS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 QVLQGLQEPAGEGLPLRKSGSVENGFDTQIYTDWANHYLAKSGHKRLIRDLQQDVTDGVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_892 QVLQGLQEPAGEGLPLRKSGSVENGFDTQIYTDWANHYLAKSGHKRLIRDLQQDVTDGVL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 LAQIIQVVANEKIEDINGCPKNRSQMIENIDACLNFLAAKGINIQGLSAEEIRNGNLKAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_892 LAQIIQVVANEKIEDINGCPKNRSQMIENIDACLNFLAAKGINIQGLSAEEIRNGNLKAI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 LGLFFSLSRYKQQQQQPQKQHLSSPLPPAVSQVAGAPSQCQAGTPQQQVPVTPQAPCQPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_892 LGLFFSLSRYKQQQQQPQKQHLSSPLPPAVSQVAGAPSQCQAGTPQQQVPVTPQAPCQPH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 QPAPHQQSKAQAEMQSRLPGPTARVSAAGSEAKTRGGSTTANNRRSQSFNNYDKSKPVTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_892 QPAPHQQSKAQAEMQSRLPGPTARVSAAGSEAKTRGGSTTANNRRSQSFNNYDKSKPVTS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 PPPPPSSHEKEPLASSASSHPGMSDNAPASLESGSSSTPTNCSTSSAIPQPGAATKPWRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_892 PPPPPSSHEKEPLASSASSHPGMSDNAPASLESGSSSTPTNCSTSSAIPQPGAATKPWRS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 KSLSVKHSATVSMLSVKPPGPEAPRPTPEAMKPAPNNQKSMLEKLKLFNSKGGSKAGEGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_892 KSLSVKHSATVSMLSVKPPGPEAPRPTPEAMKPAPNNQKSMLEKLKLFNSKGGSKAGEGP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 GSRDTSCERLETLPSFEESEELEAASRMLTTVGPASSSPKIALKGIAQRTFSRALTNKKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_892 GSRDTSCERLETLPSFEESEELEAASRMLTTVGPASSSPKIALKGIAQRTFSRALTNKKS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 SLKGNEKEKEKQQREKDKEKSKDLAKRASVTERLDLKEEPKEDPSGAAVPEMPKKSSKIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_892 SLKGNEKEKEKQQREKDKEKSKDLAKRASVTERLDLKEEPKEDPSGAAVPEMPKKSSKIA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 SFIPKGGKLNSAKKEPMAPSHSGIPKPGMKSMPGKSPSAPAPSKEGERSRSGKLSSGLPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_892 SFIPKGGKLNSAKKEPMAPSHSGIPKPGMKSMPGKSPSAPAPSKEGERSRSGKLSSGLPQ 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 QKPQLDGRHSSSSSSLASSEGKGPGGTTLNHSISSQTVSGSVGTTQTTGSNTVSVQLPQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_892 QKPQLDGRHSSSSSSLASSEGKGPGGTTLNHSISSQTVSGSVGTTQTTGSNTVSVQLPQP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 QQQYNHPNTATVAPFLYRSQTDTEGNVTAESSSTGVSVEPSHFTKTGQPALEELTGEDPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_892 QQQYNHPNTATVAPFLYRSQTDTEGNVTAESSSTGVSVEPSHFTKTGQPALEELTGEDPE 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 ARRLRTVKNIADLRQNLEETMSSLRGTQVTHSTLETTFDTNVTTEMSGRSILSLTGRPTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_892 ARRLRTVKNIADLRQNLEETMSSLRGTQVTHSTLETTFDTNVTTEMSGRSILSLTGRPTP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 LSWRLGQSSPRLQAGDAPSMGNGYPPRANASRFINTESGRYVYSAPLRRQLASRGSSVCH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_892 LSWRLGQSSPRLQAGDAPSMGNGYPPRANASRFINTESGRYVYSAPLRRQLASRGSSVCH 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 VDVSDKAGDEMDLEGISMDAPGYMSDGDVLSKNIRTDDITSGYMTDGGLGLYTRRLNRLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_892 VDVSDKAGDEMDLEGISMDAPGYMSDGDVLSKNIRTDDITSGYMTDGGLGLYTRRLNRLP 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 DGMAVVRETLQRNTSLGLGDADSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_892 DGMAVVRETLQRNTSLGLGDADSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPA 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 SSRKNLDVQTDAEKHSQVERNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_892 SSRKNLDVQTDAEKHSQVERNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESD 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA1 KSTSGKKNPVISQTGSWRRGMTAQVGITMPRTKASAPAGALKTPGTGKTDDAKVSEKGRL ::::::::::::::::::::::::::::::::: :::::::::::::::::::::::::: NP_892 KSTSGKKNPVISQTGSWRRGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRL 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA1 SPKASQVKRSPSDAGRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_892 SPKASQVKRSPSDAGRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGV 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA1 TVTSRSATLGKIPKSSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_892 TVTSRSATLGKIPKSSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSN 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA1 SRNGAGNRSSTSSIDSNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_892 SRNGAGNRSSTSSIDSNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNE 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA1 SVASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_892 SVASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMK 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA1 NSVVISNPHATMTQQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_892 NSVVISNPHATMTQQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSN 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA1 SLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_892 SLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDS 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA1 LTPFVRTNSVKTTLSESPLSSPAASPKFCRSTLPRKQDSDPHLDRNTLPKKGLRYTPTSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_892 LTPFVRTNSVKTTLSESPLSSPAASPKFCRSTLPRKQDSDPHLDRNTLPKKGLRYTPTSQ 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA1 LRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_892 LRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSN 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA1 PTMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_892 PTMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVS 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA1 STSSVYSTPEEKCQSEIRKLRRELDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_892 STSSVYSTPEEKCQSEIRKLRRELDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQ 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KA1 SLTMTAEQKDSELNELRKTIELLKKQNAAAQAAINGVINTPELNCKGNGTAQSADLRIRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_892 SLTMTAEQKDSELNELRKTIELLKKQNAAAQAAINGVINTPELNCKGNGTAQSADLRIRR 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KA1 QHSSDSVSSINSATSHSSVGSNIESDSKKKKRKNWVNELRSSFKQAFGKKKSPKSASSHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_892 QHSSDSVSSINSATSHSSVGSNIESDSKKKKRKNWVNELRSSFKQAFGKKKSPKSASSHS 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KA1 DIEEMTDSSLPSSPKLPHNGSTGSTPLLRNSHSNSLISECMDSEAETVMQLRNELRDKEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_892 DIEEMTDSSLPSSPKLPHNGSTGSTPLLRNSHSNSLISECMDSEAETVMQLRNELRDKEM 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KA1 KLTDIRLEALSSAHQLDQLREAMNRMQSEIEKLKAENDRLKSESQGSGCSRAPSQVSISA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_892 KLTDIRLEALSSAHQLDQLREAMNRMQSEIEKLKAENDRLKSESQGSGCSRAPSQVSISA 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KA1 SPRQSMGLSQHSLNLTESTSLDMLLDDTGECSARKEGGRHVKIVVSFQEEMKWKEDSRPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_892 SPRQSMGLSQHSLNLTESTSLDMLLDDTGECSARKEGGRHVKIVVSFQEEMKWKEDSRPH 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KA1 LFLIGCIGVSGKTKWDVLDGVVRRLFKEYIIHVDPVSQLGLNSDSVLGYSIGEIKRSNTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_892 LFLIGCIGVSGKTKWDVLDGVVRRLFKEYIIHVDPVSQLGLNSDSVLGYSIGEIKRSNTS 1990 2000 2010 2020 2030 2040 2050 2060 2070 2080 2090 2100 pF1KA1 ETPELLPCGYLVGENTTISVTVKGLAENSLDSLVFESLIPKPILQRYVSLLIEHRRIILS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_892 ETPELLPCGYLVGENTTISVTVKGLAENSLDSLVFESLIPKPILQRYVSLLIEHRRIILS 2050 2060 2070 2080 2090 2100 2110 2120 2130 2140 2150 2160 pF1KA1 GPSGTGKTYLANRLSEYIVLREGRELTDGVIATFNVDHKSSKELRQYLSNLADQCNSENN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_892 GPSGTGKTYLANRLSEYIVLREGRELTDGVIATFNVDHKSSKELRQYLSNLADQCNSENN 2110 2120 2130 2140 2150 2160 2170 2180 2190 2200 2210 2220 pF1KA1 AVDMPLVIILDNLHHVSSLGEIFNGLLNCKYHKCPYIIGTMNQATSSTPNLQLHHNFRWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_892 AVDMPLVIILDNLHHVSSLGEIFNGLLNCKYHKCPYIIGTMNQATSSTPNLQLHHNFRWV 2170 2180 2190 2200 2210 2220 2230 2240 2250 2260 2270 2280 pF1KA1 LCANHTEPVKGFLGRFLRRKLMETEISGRVRNMELVKIIDWIPKVWHHLNRFLEAHSSSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_892 LCANHTEPVKGFLGRFLRRKLMETEISGRVRNMELVKIIDWIPKVWHHLNRFLEAHSSSD 2230 2240 2250 2260 2270 2280 2290 2300 2310 2320 2330 2340 pF1KA1 VTIGPRLFLSCPIDVDGSRVWFTDLWNYSIIPYLLEAVREGLQLYGRRAPWEDPAKWVMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_892 VTIGPRLFLSCPIDVDGSRVWFTDLWNYSIIPYLLEAVREGLQLYGRRAPWEDPAKWVMD 2290 2300 2310 2320 2330 2340 2350 2360 2370 2380 2390 2400 pF1KA1 TYPWAASPQQHEWPPLLQLRPEDVGFDGYSMPREGSTSKQMPPSDAEGDPLMNMLMRLQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_892 TYPWAASPQQHEWPPLLQLRPEDVGFDGYSMPREGSTSKQMPPSDAEGDPLMNMLMRLQE 2350 2360 2370 2380 2390 2400 2410 2420 2430 pF1KA1 AANYSSPQSYDSDSNSNSHHDDILDSSLESTL :::::::::::::::::::::::::::::::: NP_892 AANYSSPQSYDSDSNSNSHHDDILDSSLESTL 2410 2420 2430 >>NP_660093 (OMIM: 607026) neuron navigator 2 isoform 2 (2429 aa) initn: 11484 init1: 11484 opt: 15808 Z-score: 7283.7 bits: 1361.8 E(85289): 0 Smith-Waterman score: 15808; 99.8% identity (99.8% similar) in 2432 aa overlap (1-2432:1-2429) 10 20 30 40 50 60 pF1KA1 MPAILVASKMKSGLPKPVHSAAPILHVPPARAGPQPCYLKLGSKVEVSKTTYPSQIPLKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 MPAILVASKMKSGLPKPVHSAAPILHVPPARAGPQPCYLKLGSKVEVSKTTYPSQIPLKS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 QVLQGLQEPAGEGLPLRKSGSVENGFDTQIYTDWANHYLAKSGHKRLIRDLQQDVTDGVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 QVLQGLQEPAGEGLPLRKSGSVENGFDTQIYTDWANHYLAKSGHKRLIRDLQQDVTDGVL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 LAQIIQVVANEKIEDINGCPKNRSQMIENIDACLNFLAAKGINIQGLSAEEIRNGNLKAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 LAQIIQVVANEKIEDINGCPKNRSQMIENIDACLNFLAAKGINIQGLSAEEIRNGNLKAI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 LGLFFSLSRYKQQQQQPQKQHLSSPLPPAVSQVAGAPSQCQAGTPQQQVPVTPQAPCQPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 LGLFFSLSRYKQQQQQPQKQHLSSPLPPAVSQVAGAPSQCQAGTPQQQVPVTPQAPCQPH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 QPAPHQQSKAQAEMQSRLPGPTARVSAAGSEAKTRGGSTTANNRRSQSFNNYDKSKPVTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 QPAPHQQSKAQAEMQSRLPGPTARVSAAGSEAKTRGGSTTANNRRSQSFNNYDKSKPVTS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 PPPPPSSHEKEPLASSASSHPGMSDNAPASLESGSSSTPTNCSTSSAIPQPGAATKPWRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 PPPPPSSHEKEPLASSASSHPGMSDNAPASLESGSSSTPTNCSTSSAIPQPGAATKPWRS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 KSLSVKHSATVSMLSVKPPGPEAPRPTPEAMKPAPNNQKSMLEKLKLFNSKGGSKAGEGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 KSLSVKHSATVSMLSVKPPGPEAPRPTPEAMKPAPNNQKSMLEKLKLFNSKGGSKAGEGP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 GSRDTSCERLETLPSFEESEELEAASRMLTTVGPASSSPKIALKGIAQRTFSRALTNKKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 GSRDTSCERLETLPSFEESEELEAASRMLTTVGPASSSPKIALKGIAQRTFSRALTNKKS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 SLKGNEKEKEKQQREKDKEKSKDLAKRASVTERLDLKEEPKEDPSGAAVPEMPKKSSKIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 SLKGNEKEKEKQQREKDKEKSKDLAKRASVTERLDLKEEPKEDPSGAAVPEMPKKSSKIA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 SFIPKGGKLNSAKKEPMAPSHSGIPKPGMKSMPGKSPSAPAPSKEGERSRSGKLSSGLPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 SFIPKGGKLNSAKKEPMAPSHSGIPKPGMKSMPGKSPSAPAPSKEGERSRSGKLSSGLPQ 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 QKPQLDGRHSSSSSSLASSEGKGPGGTTLNHSISSQTVSGSVGTTQTTGSNTVSVQLPQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 QKPQLDGRHSSSSSSLASSEGKGPGGTTLNHSISSQTVSGSVGTTQTTGSNTVSVQLPQP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 QQQYNHPNTATVAPFLYRSQTDTEGNVTAESSSTGVSVEPSHFTKTGQPALEELTGEDPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 QQQYNHPNTATVAPFLYRSQTDTEGNVTAESSSTGVSVEPSHFTKTGQPALEELTGEDPE 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 ARRLRTVKNIADLRQNLEETMSSLRGTQVTHSTLETTFDTNVTTEMSGRSILSLTGRPTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 ARRLRTVKNIADLRQNLEETMSSLRGTQVTHSTLETTFDTNVTTEMSGRSILSLTGRPTP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 LSWRLGQSSPRLQAGDAPSMGNGYPPRANASRFINTESGRYVYSAPLRRQLASRGSSVCH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 LSWRLGQSSPRLQAGDAPSMGNGYPPRANASRFINTESGRYVYSAPLRRQLASRGSSVCH 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 VDVSDKAGDEMDLEGISMDAPGYMSDGDVLSKNIRTDDITSGYMTDGGLGLYTRRLNRLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 VDVSDKAGDEMDLEGISMDAPGYMSDGDVLSKNIRTDDITSGYMTDGGLGLYTRRLNRLP 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 DGMAVVRETLQRNTSLGLGDADSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 DGMAVVRETLQRNTSLGLGDADSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPA 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 SSRKNLDVQTDAEKHSQVERNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 SSRKNLDVQTDAEKHSQVERNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESD 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA1 KSTSGKKNPVISQTGSWRRGMTAQVGITMPRTKASAPAGALKTPGTGKTDDAKVSEKGRL ::::::::::::::::::::::::::::::::: :::::::::::::::::::::::::: NP_660 KSTSGKKNPVISQTGSWRRGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRL 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA1 SPKASQVKRSPSDAGRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 SPKASQVKRSPSDAGRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGV 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA1 TVTSRSATLGKIPKSSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 TVTSRSATLGKIPKSSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSN 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA1 SRNGAGNRSSTSSIDSNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 SRNGAGNRSSTSSIDSNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNE 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA1 SVASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 SVASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMK 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA1 NSVVISNPHATMTQQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 NSVVISNPHATMTQQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSN 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA1 SLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 SLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDS 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA1 LTPFVRTNSVKTTLSESPLSSPAASPKFCRSTLPRKQDSDPHLDRNTLPKKGLRYTPTSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 LTPFVRTNSVKTTLSESPLSSPAASPKFCRSTLPRKQDSDPHLDRNTLPKKGLRYTPTSQ 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA1 LRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 LRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSN 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA1 PTMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 PTMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVS 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA1 STSSVYSTPEEKCQSEIRKLRRELDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 STSSVYSTPEEKCQSEIRKLRRELDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQ 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KA1 SLTMTAEQKDSELNELRKTIELLKKQNAAAQAAINGVINTPELNCKGNGTAQSADLRIRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 SLTMTAEQKDSELNELRKTIELLKKQNAAAQAAINGVINTPELNCKGNGTAQSADLRIRR 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KA1 QHSSDSVSSINSATSHSSVGSNIESDSKKKKRKNWVNELRSSFKQAFGKKKSPKSASSHS ::::::::::::::::::::::::::::::::::: :::::::::::::::::::::: NP_660 QHSSDSVSSINSATSHSSVGSNIESDSKKKKRKNW---LRSSFKQAFGKKKSPKSASSHS 1750 1760 1770 1780 1790 1810 1820 1830 1840 1850 1860 pF1KA1 DIEEMTDSSLPSSPKLPHNGSTGSTPLLRNSHSNSLISECMDSEAETVMQLRNELRDKEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 DIEEMTDSSLPSSPKLPHNGSTGSTPLLRNSHSNSLISECMDSEAETVMQLRNELRDKEM 1800 1810 1820 1830 1840 1850 1870 1880 1890 1900 1910 1920 pF1KA1 KLTDIRLEALSSAHQLDQLREAMNRMQSEIEKLKAENDRLKSESQGSGCSRAPSQVSISA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 KLTDIRLEALSSAHQLDQLREAMNRMQSEIEKLKAENDRLKSESQGSGCSRAPSQVSISA 1860 1870 1880 1890 1900 1910 1930 1940 1950 1960 1970 1980 pF1KA1 SPRQSMGLSQHSLNLTESTSLDMLLDDTGECSARKEGGRHVKIVVSFQEEMKWKEDSRPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 SPRQSMGLSQHSLNLTESTSLDMLLDDTGECSARKEGGRHVKIVVSFQEEMKWKEDSRPH 1920 1930 1940 1950 1960 1970 1990 2000 2010 2020 2030 2040 pF1KA1 LFLIGCIGVSGKTKWDVLDGVVRRLFKEYIIHVDPVSQLGLNSDSVLGYSIGEIKRSNTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 LFLIGCIGVSGKTKWDVLDGVVRRLFKEYIIHVDPVSQLGLNSDSVLGYSIGEIKRSNTS 1980 1990 2000 2010 2020 2030 2050 2060 2070 2080 2090 2100 pF1KA1 ETPELLPCGYLVGENTTISVTVKGLAENSLDSLVFESLIPKPILQRYVSLLIEHRRIILS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 ETPELLPCGYLVGENTTISVTVKGLAENSLDSLVFESLIPKPILQRYVSLLIEHRRIILS 2040 2050 2060 2070 2080 2090 2110 2120 2130 2140 2150 2160 pF1KA1 GPSGTGKTYLANRLSEYIVLREGRELTDGVIATFNVDHKSSKELRQYLSNLADQCNSENN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 GPSGTGKTYLANRLSEYIVLREGRELTDGVIATFNVDHKSSKELRQYLSNLADQCNSENN 2100 2110 2120 2130 2140 2150 2170 2180 2190 2200 2210 2220 pF1KA1 AVDMPLVIILDNLHHVSSLGEIFNGLLNCKYHKCPYIIGTMNQATSSTPNLQLHHNFRWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 AVDMPLVIILDNLHHVSSLGEIFNGLLNCKYHKCPYIIGTMNQATSSTPNLQLHHNFRWV 2160 2170 2180 2190 2200 2210 2230 2240 2250 2260 2270 2280 pF1KA1 LCANHTEPVKGFLGRFLRRKLMETEISGRVRNMELVKIIDWIPKVWHHLNRFLEAHSSSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 LCANHTEPVKGFLGRFLRRKLMETEISGRVRNMELVKIIDWIPKVWHHLNRFLEAHSSSD 2220 2230 2240 2250 2260 2270 2290 2300 2310 2320 2330 2340 pF1KA1 VTIGPRLFLSCPIDVDGSRVWFTDLWNYSIIPYLLEAVREGLQLYGRRAPWEDPAKWVMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 VTIGPRLFLSCPIDVDGSRVWFTDLWNYSIIPYLLEAVREGLQLYGRRAPWEDPAKWVMD 2280 2290 2300 2310 2320 2330 2350 2360 2370 2380 2390 2400 pF1KA1 TYPWAASPQQHEWPPLLQLRPEDVGFDGYSMPREGSTSKQMPPSDAEGDPLMNMLMRLQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_660 TYPWAASPQQHEWPPLLQLRPEDVGFDGYSMPREGSTSKQMPPSDAEGDPLMNMLMRLQE 2340 2350 2360 2370 2380 2390 2410 2420 2430 pF1KA1 AANYSSPQSYDSDSNSNSHHDDILDSSLESTL :::::::::::::::::::::::::::::::: NP_660 AANYSSPQSYDSDSNSNSHHDDILDSSLESTL 2400 2410 2420 >>NP_001104488 (OMIM: 607026) neuron navigator 2 isoform (2365 aa) initn: 10892 init1: 10892 opt: 15228 Z-score: 7017.1 bits: 1312.4 E(85289): 0 Smith-Waterman score: 15228; 99.1% identity (99.4% similar) in 2367 aa overlap (68-2432:2-2365) 40 50 60 70 80 90 pF1KA1 YLKLGSKVEVSKTTYPSQIPLKSQVLQGLQEPAGEGLPLRKSGSVENGFDTQ--IYTDWA : ..:. .: : .:.. : :::::: NP_001 MESVSESSQQQKRKPVIHGLEDQKRIYTDWA 10 20 30 100 110 120 130 140 150 pF1KA1 NHYLAKSGHKRLIRDLQQDVTDGVLLAQIIQVVANEKIEDINGCPKNRSQMIENIDACLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NHYLAKSGHKRLIRDLQQDVTDGVLLAQIIQVVANEKIEDINGCPKNRSQMIENIDACLN 40 50 60 70 80 90 160 170 180 190 200 210 pF1KA1 FLAAKGINIQGLSAEEIRNGNLKAILGLFFSLSRYKQQQQQPQKQHLSSPLPPAVSQVAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FLAAKGINIQGLSAEEIRNGNLKAILGLFFSLSRYKQQQQQPQKQHLSSPLPPAVSQVAG 100 110 120 130 140 150 220 230 240 250 260 270 pF1KA1 APSQCQAGTPQQQVPVTPQAPCQPHQPAPHQQSKAQAEMQSRLPGPTARVSAAGSEAKTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 APSQCQAGTPQQQVPVTPQAPCQPHQPAPHQQSKAQAEMQSRLPGPTARVSAAGSEAKTR 160 170 180 190 200 210 280 290 300 310 320 330 pF1KA1 GGSTTANNRRSQSFNNYDKSKPVTSPPPPPSSHEKEPLASSASSHPGMSDNAPASLESGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GGSTTANNRRSQSFNNYDKSKPVTSPPPPPSSHEKEPLASSASSHPGMSDNAPASLESGS 220 230 240 250 260 270 340 350 360 370 380 390 pF1KA1 SSTPTNCSTSSAIPQPGAATKPWRSKSLSVKHSATVSMLSVKPPGPEAPRPTPEAMKPAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSTPTNCSTSSAIPQPGAATKPWRSKSLSVKHSATVSMLSVKPPGPEAPRPTPEAMKPAP 280 290 300 310 320 330 400 410 420 430 440 450 pF1KA1 NNQKSMLEKLKLFNSKGGSKAGEGPGSRDTSCERLETLPSFEESEELEAASRMLTTVGPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NNQKSMLEKLKLFNSKGGSKAGEGPGSRDTSCERLETLPSFEESEELEAASRMLTTVGPA 340 350 360 370 380 390 460 470 480 490 500 510 pF1KA1 SSSPKIALKGIAQRTFSRALTNKKSSLKGNEKEKEKQQREKDKEKSKDLAKRASVTERLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSSPKIALKGIAQRTFSRALTNKKSSLKGNEKEKEKQQREKDKEKSKDLAKRASVTERLD 400 410 420 430 440 450 520 530 540 550 560 570 pF1KA1 LKEEPKEDPSGAAVPEMPKKSSKIASFIPKGGKLNSAKKEPMAPSHSGIPKPGMKSMPGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKEEPKEDPSGAAVPEMPKKSSKIASFIPKGGKLNSAKKEPMAPSHSGIPKPGMKSMPGK 460 470 480 490 500 510 580 590 600 610 620 630 pF1KA1 SPSAPAPSKEGERSRSGKLSSGLPQQKPQLDGRHSSSSSSLASSEGKGPGGTTLNHSISS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPSAPAPSKEGERSRSGKLSSGLPQQKPQLDGRHSSSSSSLASSEGKGPGGTTLNHSISS 520 530 540 550 560 570 640 650 660 670 680 690 pF1KA1 QTVSGSVGTTQTTGSNTVSVQLPQPQQQYNHPNTATVAPFLYRSQTDTEGNVTAESSSTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QTVSGSVGTTQTTGSNTVSVQLPQPQQQYNHPNTATVAPFLYRSQTDTEGNVTAESSSTG 580 590 600 610 620 630 700 710 720 730 740 750 pF1KA1 VSVEPSHFTKTGQPALEELTGEDPEARRLRTVKNIADLRQNLEETMSSLRGTQVTHSTLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VSVEPSHFTKTGQPALEELTGEDPEARRLRTVKNIADLRQNLEETMSSLRGTQVTHSTLE 640 650 660 670 680 690 760 770 780 790 800 810 pF1KA1 TTFDTNVTTEMSGRSILSLTGRPTPLSWRLGQSSPRLQAGDAPSMGNGYPPRANASRFIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TTFDTNVTTEMSGRSILSLTGRPTPLSWRLGQSSPRLQAGDAPSMGNGYPPRANASRFIN 700 710 720 730 740 750 820 830 840 850 860 870 pF1KA1 TESGRYVYSAPLRRQLASRGSSVCHVDVSDKAGDEMDLEGISMDAPGYMSDGDVLSKNIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TESGRYVYSAPLRRQLASRGSSVCHVDVSDKAGDEMDLEGISMDAPGYMSDGDVLSKNIR 760 770 780 790 800 810 880 890 900 910 920 930 pF1KA1 TDDITSGYMTDGGLGLYTRRLNRLPDGMAVVRETLQRNTSLGLGDADSWDDSSSVSSGIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TDDITSGYMTDGGLGLYTRRLNRLPDGMAVVRETLQRNTSLGLGDADSWDDSSSVSSGIS 820 830 840 850 860 870 940 950 960 970 980 990 pF1KA1 DTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNSLWSGDDVKKSDGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNSLWSGDDVKKSDGG 880 890 900 910 920 930 1000 1010 1020 1030 1040 1050 pF1KA1 SDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGITMPRTKAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: : NP_001 SDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGITMPRTKPS 940 950 960 970 980 990 1060 1070 1080 1090 1100 1110 pF1KA1 APAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDESKKPLPSSSRTPTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 APAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDESKKPLPSSSRTPTA 1000 1010 1020 1030 1040 1050 1120 1130 1140 1150 1160 1170 pF1KA1 NANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSRSAGRKSSMDGAQNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSRSAGRKSSMDGAQNQ 1060 1070 1080 1090 1100 1110 1180 1190 1200 1210 1220 1230 pF1KA1 DDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSKSAGLPVPKLREPSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSKSAGLPVPKLREPSK 1120 1130 1140 1150 1160 1170 1240 1250 1260 1270 1280 1290 pF1KA1 TALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVA 1180 1190 1200 1210 1220 1230 1300 1310 1320 1330 1340 1350 pF1KA1 SPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSPSGSGVLSSGSSSPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSPSGSGVLSSGSSSPL 1240 1250 1260 1270 1280 1290 1360 1370 1380 1390 1400 1410 pF1KA1 YSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESID 1300 1310 1320 1330 1340 1350 1420 1430 1440 1450 1460 1470 pF1KA1 ISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESPLSSPAASPKFCRSTLPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESPLSSPAASPKFCRSTLPR 1360 1370 1380 1390 1400 1410 1480 1490 1500 1510 1520 1530 pF1KA1 KQDSDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KQDSDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVT 1420 1430 1440 1450 1460 1470 1540 1550 1560 1570 1580 1590 pF1KA1 SPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKS 1480 1490 1500 1510 1520 1530 1600 1610 1620 1630 1640 1650 pF1KA1 RTMSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRELDASQEKVSALT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RTMSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRELDASQEKVSALT 1540 1550 1560 1570 1580 1590 1660 1670 1680 1690 1700 1710 pF1KA1 TQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAIN 1600 1610 1620 1630 1640 1650 1720 1730 1740 1750 1760 1770 pF1KA1 GVINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVGSNIESDSKKKKRKNW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GVINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVGSNIESDSKKKKRKNW 1660 1670 1680 1690 1700 1710 1780 1790 1800 1810 1820 1830 pF1KA1 VNELRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNGSTGSTPLLRNSHSNS ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ---LRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNGSTGSTPLLRNSHSNS 1720 1730 1740 1750 1760 1840 1850 1860 1870 1880 1890 pF1KA1 LISECMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQLREAMNRMQSEIEKLKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LISECMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQLREAMNRMQSEIEKLKA 1770 1780 1790 1800 1810 1820 1900 1910 1920 1930 1940 1950 pF1KA1 ENDRLKSESQGSGCSRAPSQVSISASPRQSMGLSQHSLNLTESTSLDMLLDDTGECSARK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENDRLKSESQGSGCSRAPSQVSISASPRQSMGLSQHSLNLTESTSLDMLLDDTGECSARK 1830 1840 1850 1860 1870 1880 1960 1970 1980 1990 2000 2010 pF1KA1 EGGRHVKIVVSFQEEMKWKEDSRPHLFLIGCIGVSGKTKWDVLDGVVRRLFKEYIIHVDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EGGRHVKIVVSFQEEMKWKEDSRPHLFLIGCIGVSGKTKWDVLDGVVRRLFKEYIIHVDP 1890 1900 1910 1920 1930 1940 2020 2030 2040 2050 2060 2070 pF1KA1 VSQLGLNSDSVLGYSIGEIKRSNTSETPELLPCGYLVGENTTISVTVKGLAENSLDSLVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VSQLGLNSDSVLGYSIGEIKRSNTSETPELLPCGYLVGENTTISVTVKGLAENSLDSLVF 1950 1960 1970 1980 1990 2000 2080 2090 2100 2110 2120 2130 pF1KA1 ESLIPKPILQRYVSLLIEHRRIILSGPSGTGKTYLANRLSEYIVLREGRELTDGVIATFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ESLIPKPILQRYVSLLIEHRRIILSGPSGTGKTYLANRLSEYIVLREGRELTDGVIATFN 2010 2020 2030 2040 2050 2060 2140 2150 2160 2170 2180 2190 pF1KA1 VDHKSSKELRQYLSNLADQCNSENNAVDMPLVIILDNLHHVSSLGEIFNGLLNCKYHKCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VDHKSSKELRQYLSNLADQCNSENNAVDMPLVIILDNLHHVSSLGEIFNGLLNCKYHKCP 2070 2080 2090 2100 2110 2120 2200 2210 2220 2230 2240 2250 pF1KA1 YIIGTMNQATSSTPNLQLHHNFRWVLCANHTEPVKGFLGRFLRRKLMETEISGRVRNMEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YIIGTMNQATSSTPNLQLHHNFRWVLCANHTEPVKGFLGRFLRRKLMETEISGRVRNMEL 2130 2140 2150 2160 2170 2180 2260 2270 2280 2290 2300 2310 pF1KA1 VKIIDWIPKVWHHLNRFLEAHSSSDVTIGPRLFLSCPIDVDGSRVWFTDLWNYSIIPYLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VKIIDWIPKVWHHLNRFLEAHSSSDVTIGPRLFLSCPIDVDGSRVWFTDLWNYSIIPYLL 2190 2200 2210 2220 2230 2240 2320 2330 2340 2350 2360 2370 pF1KA1 EAVREGLQLYGRRAPWEDPAKWVMDTYPWAASPQQHEWPPLLQLRPEDVGFDGYSMPREG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EAVREGLQLYGRRAPWEDPAKWVMDTYPWAASPQQHEWPPLLQLRPEDVGFDGYSMPREG 2250 2260 2270 2280 2290 2300 2380 2390 2400 2410 2420 2430 pF1KA1 STSKQMPPSDAEGDPLMNMLMRLQEAANYSSPQSYDSDSNSNSHHDDILDSSLESTL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STSKQMPPSDAEGDPLMNMLMRLQEAANYSSPQSYDSDSNSNSHHDDILDSSLESTL 2310 2320 2330 2340 2350 2360 >>XP_011518754 (OMIM: 607026) PREDICTED: neuron navigato (2365 aa) initn: 10892 init1: 10892 opt: 15228 Z-score: 7017.1 bits: 1312.4 E(85289): 0 Smith-Waterman score: 15228; 99.1% identity (99.4% similar) in 2367 aa overlap (68-2432:2-2365) 40 50 60 70 80 90 pF1KA1 YLKLGSKVEVSKTTYPSQIPLKSQVLQGLQEPAGEGLPLRKSGSVENGFDTQ--IYTDWA : ..:. .: : .:.. : :::::: XP_011 MESVSESSQQQKRKPVIHGLEDQKRIYTDWA 10 20 30 100 110 120 130 140 150 pF1KA1 NHYLAKSGHKRLIRDLQQDVTDGVLLAQIIQVVANEKIEDINGCPKNRSQMIENIDACLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NHYLAKSGHKRLIRDLQQDVTDGVLLAQIIQVVANEKIEDINGCPKNRSQMIENIDACLN 40 50 60 70 80 90 160 170 180 190 200 210 pF1KA1 FLAAKGINIQGLSAEEIRNGNLKAILGLFFSLSRYKQQQQQPQKQHLSSPLPPAVSQVAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FLAAKGINIQGLSAEEIRNGNLKAILGLFFSLSRYKQQQQQPQKQHLSSPLPPAVSQVAG 100 110 120 130 140 150 220 230 240 250 260 270 pF1KA1 APSQCQAGTPQQQVPVTPQAPCQPHQPAPHQQSKAQAEMQSRLPGPTARVSAAGSEAKTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APSQCQAGTPQQQVPVTPQAPCQPHQPAPHQQSKAQAEMQSRLPGPTARVSAAGSEAKTR 160 170 180 190 200 210 280 290 300 310 320 330 pF1KA1 GGSTTANNRRSQSFNNYDKSKPVTSPPPPPSSHEKEPLASSASSHPGMSDNAPASLESGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GGSTTANNRRSQSFNNYDKSKPVTSPPPPPSSHEKEPLASSASSHPGMSDNAPASLESGS 220 230 240 250 260 270 340 350 360 370 380 390 pF1KA1 SSTPTNCSTSSAIPQPGAATKPWRSKSLSVKHSATVSMLSVKPPGPEAPRPTPEAMKPAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSTPTNCSTSSAIPQPGAATKPWRSKSLSVKHSATVSMLSVKPPGPEAPRPTPEAMKPAP 280 290 300 310 320 330 400 410 420 430 440 450 pF1KA1 NNQKSMLEKLKLFNSKGGSKAGEGPGSRDTSCERLETLPSFEESEELEAASRMLTTVGPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NNQKSMLEKLKLFNSKGGSKAGEGPGSRDTSCERLETLPSFEESEELEAASRMLTTVGPA 340 350 360 370 380 390 460 470 480 490 500 510 pF1KA1 SSSPKIALKGIAQRTFSRALTNKKSSLKGNEKEKEKQQREKDKEKSKDLAKRASVTERLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSSPKIALKGIAQRTFSRALTNKKSSLKGNEKEKEKQQREKDKEKSKDLAKRASVTERLD 400 410 420 430 440 450 520 530 540 550 560 570 pF1KA1 LKEEPKEDPSGAAVPEMPKKSSKIASFIPKGGKLNSAKKEPMAPSHSGIPKPGMKSMPGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKEEPKEDPSGAAVPEMPKKSSKIASFIPKGGKLNSAKKEPMAPSHSGIPKPGMKSMPGK 460 470 480 490 500 510 580 590 600 610 620 630 pF1KA1 SPSAPAPSKEGERSRSGKLSSGLPQQKPQLDGRHSSSSSSLASSEGKGPGGTTLNHSISS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPSAPAPSKEGERSRSGKLSSGLPQQKPQLDGRHSSSSSSLASSEGKGPGGTTLNHSISS 520 530 540 550 560 570 640 650 660 670 680 690 pF1KA1 QTVSGSVGTTQTTGSNTVSVQLPQPQQQYNHPNTATVAPFLYRSQTDTEGNVTAESSSTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QTVSGSVGTTQTTGSNTVSVQLPQPQQQYNHPNTATVAPFLYRSQTDTEGNVTAESSSTG 580 590 600 610 620 630 700 710 720 730 740 750 pF1KA1 VSVEPSHFTKTGQPALEELTGEDPEARRLRTVKNIADLRQNLEETMSSLRGTQVTHSTLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSVEPSHFTKTGQPALEELTGEDPEARRLRTVKNIADLRQNLEETMSSLRGTQVTHSTLE 640 650 660 670 680 690 760 770 780 790 800 810 pF1KA1 TTFDTNVTTEMSGRSILSLTGRPTPLSWRLGQSSPRLQAGDAPSMGNGYPPRANASRFIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TTFDTNVTTEMSGRSILSLTGRPTPLSWRLGQSSPRLQAGDAPSMGNGYPPRANASRFIN 700 710 720 730 740 750 820 830 840 850 860 870 pF1KA1 TESGRYVYSAPLRRQLASRGSSVCHVDVSDKAGDEMDLEGISMDAPGYMSDGDVLSKNIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TESGRYVYSAPLRRQLASRGSSVCHVDVSDKAGDEMDLEGISMDAPGYMSDGDVLSKNIR 760 770 780 790 800 810 880 890 900 910 920 930 pF1KA1 TDDITSGYMTDGGLGLYTRRLNRLPDGMAVVRETLQRNTSLGLGDADSWDDSSSVSSGIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TDDITSGYMTDGGLGLYTRRLNRLPDGMAVVRETLQRNTSLGLGDADSWDDSSSVSSGIS 820 830 840 850 860 870 940 950 960 970 980 990 pF1KA1 DTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNSLWSGDDVKKSDGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNSLWSGDDVKKSDGG 880 890 900 910 920 930 1000 1010 1020 1030 1040 1050 pF1KA1 SDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGITMPRTKAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: : XP_011 SDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGITMPRTKPS 940 950 960 970 980 990 1060 1070 1080 1090 1100 1110 pF1KA1 APAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDESKKPLPSSSRTPTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDESKKPLPSSSRTPTA 1000 1010 1020 1030 1040 1050 1120 1130 1140 1150 1160 1170 pF1KA1 NANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSRSAGRKSSMDGAQNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSRSAGRKSSMDGAQNQ 1060 1070 1080 1090 1100 1110 1180 1190 1200 1210 1220 1230 pF1KA1 DDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSKSAGLPVPKLREPSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSKSAGLPVPKLREPSK 1120 1130 1140 1150 1160 1170 1240 1250 1260 1270 1280 1290 pF1KA1 TALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVA 1180 1190 1200 1210 1220 1230 1300 1310 1320 1330 1340 1350 pF1KA1 SPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSPSGSGVLSSGSSSPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSPSGSGVLSSGSSSPL 1240 1250 1260 1270 1280 1290 1360 1370 1380 1390 1400 1410 pF1KA1 YSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESID 1300 1310 1320 1330 1340 1350 1420 1430 1440 1450 1460 1470 pF1KA1 ISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESPLSSPAASPKFCRSTLPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESPLSSPAASPKFCRSTLPR 1360 1370 1380 1390 1400 1410 1480 1490 1500 1510 1520 1530 pF1KA1 KQDSDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KQDSDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVT 1420 1430 1440 1450 1460 1470 1540 1550 1560 1570 1580 1590 pF1KA1 SPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKS 1480 1490 1500 1510 1520 1530 1600 1610 1620 1630 1640 1650 pF1KA1 RTMSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRELDASQEKVSALT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RTMSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRELDASQEKVSALT 1540 1550 1560 1570 1580 1590 1660 1670 1680 1690 1700 1710 pF1KA1 TQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAIN 1600 1610 1620 1630 1640 1650 1720 1730 1740 1750 1760 1770 pF1KA1 GVINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVGSNIESDSKKKKRKNW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GVINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVGSNIESDSKKKKRKNW 1660 1670 1680 1690 1700 1710 1780 1790 1800 1810 1820 1830 pF1KA1 VNELRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNGSTGSTPLLRNSHSNS ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ---LRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNGSTGSTPLLRNSHSNS 1720 1730 1740 1750 1760 1840 1850 1860 1870 1880 1890 pF1KA1 LISECMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQLREAMNRMQSEIEKLKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LISECMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQLREAMNRMQSEIEKLKA 1770 1780 1790 1800 1810 1820 1900 1910 1920 1930 1940 1950 pF1KA1 ENDRLKSESQGSGCSRAPSQVSISASPRQSMGLSQHSLNLTESTSLDMLLDDTGECSARK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ENDRLKSESQGSGCSRAPSQVSISASPRQSMGLSQHSLNLTESTSLDMLLDDTGECSARK 1830 1840 1850 1860 1870 1880 1960 1970 1980 1990 2000 2010 pF1KA1 EGGRHVKIVVSFQEEMKWKEDSRPHLFLIGCIGVSGKTKWDVLDGVVRRLFKEYIIHVDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EGGRHVKIVVSFQEEMKWKEDSRPHLFLIGCIGVSGKTKWDVLDGVVRRLFKEYIIHVDP 1890 1900 1910 1920 1930 1940 2020 2030 2040 2050 2060 2070 pF1KA1 VSQLGLNSDSVLGYSIGEIKRSNTSETPELLPCGYLVGENTTISVTVKGLAENSLDSLVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSQLGLNSDSVLGYSIGEIKRSNTSETPELLPCGYLVGENTTISVTVKGLAENSLDSLVF 1950 1960 1970 1980 1990 2000 2080 2090 2100 2110 2120 2130 pF1KA1 ESLIPKPILQRYVSLLIEHRRIILSGPSGTGKTYLANRLSEYIVLREGRELTDGVIATFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ESLIPKPILQRYVSLLIEHRRIILSGPSGTGKTYLANRLSEYIVLREGRELTDGVIATFN 2010 2020 2030 2040 2050 2060 2140 2150 2160 2170 2180 2190 pF1KA1 VDHKSSKELRQYLSNLADQCNSENNAVDMPLVIILDNLHHVSSLGEIFNGLLNCKYHKCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VDHKSSKELRQYLSNLADQCNSENNAVDMPLVIILDNLHHVSSLGEIFNGLLNCKYHKCP 2070 2080 2090 2100 2110 2120 2200 2210 2220 2230 2240 2250 pF1KA1 YIIGTMNQATSSTPNLQLHHNFRWVLCANHTEPVKGFLGRFLRRKLMETEISGRVRNMEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YIIGTMNQATSSTPNLQLHHNFRWVLCANHTEPVKGFLGRFLRRKLMETEISGRVRNMEL 2130 2140 2150 2160 2170 2180 2260 2270 2280 2290 2300 2310 pF1KA1 VKIIDWIPKVWHHLNRFLEAHSSSDVTIGPRLFLSCPIDVDGSRVWFTDLWNYSIIPYLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VKIIDWIPKVWHHLNRFLEAHSSSDVTIGPRLFLSCPIDVDGSRVWFTDLWNYSIIPYLL 2190 2200 2210 2220 2230 2240 2320 2330 2340 2350 2360 2370 pF1KA1 EAVREGLQLYGRRAPWEDPAKWVMDTYPWAASPQQHEWPPLLQLRPEDVGFDGYSMPREG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EAVREGLQLYGRRAPWEDPAKWVMDTYPWAASPQQHEWPPLLQLRPEDVGFDGYSMPREG 2250 2260 2270 2280 2290 2300 2380 2390 2400 2410 2420 2430 pF1KA1 STSKQMPPSDAEGDPLMNMLMRLQEAANYSSPQSYDSDSNSNSHHDDILDSSLESTL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STSKQMPPSDAEGDPLMNMLMRLQEAANYSSPQSYDSDSNSNSHHDDILDSSLESTL 2310 2320 2330 2340 2350 2360 >>XP_006718428 (OMIM: 607026) PREDICTED: neuron navigato (2455 aa) initn: 15891 init1: 14125 opt: 14148 Z-score: 6520.0 bits: 1220.5 E(85289): 0 Smith-Waterman score: 15786; 99.0% identity (99.0% similar) in 2455 aa overlap (1-2432:1-2455) 10 20 30 40 50 60 pF1KA1 MPAILVASKMKSGLPKPVHSAAPILHVPPARAGPQPCYLKLGSKVEVSKTTYPSQIPLKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MPAILVASKMKSGLPKPVHSAAPILHVPPARAGPQPCYLKLGSKVEVSKTTYPSQIPLKS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 QVLQGLQEPAGEGLPLRKSGSVENGFDTQIYTDWANHYLAKSGHKRLIRDLQQDVTDGVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QVLQGLQEPAGEGLPLRKSGSVENGFDTQIYTDWANHYLAKSGHKRLIRDLQQDVTDGVL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 LAQIIQVVANEKIEDINGCPKNRSQMIENIDACLNFLAAKGINIQGLSAEEIRNGNLKAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LAQIIQVVANEKIEDINGCPKNRSQMIENIDACLNFLAAKGINIQGLSAEEIRNGNLKAI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 LGLFFSLSRYKQQQQQPQKQHLSSPLPPAVSQVAGAPSQCQAGTPQQQVPVTPQAPCQPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LGLFFSLSRYKQQQQQPQKQHLSSPLPPAVSQVAGAPSQCQAGTPQQQVPVTPQAPCQPH 190 200 210 220 230 240 250 260 270 pF1KA1 QPAPHQQSKAQAEMQS-----------------------RLPGPTARVSAAGSEAKTRGG :::::::::::::::: ::::::::::::::::::::: XP_006 QPAPHQQSKAQAEMQSSASSKDSSQSKIIRFTLGQKKISRLPGPTARVSAAGSEAKTRGG 250 260 270 280 290 300 280 290 300 310 320 330 pF1KA1 STTANNRRSQSFNNYDKSKPVTSPPPPPSSHEKEPLASSASSHPGMSDNAPASLESGSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 STTANNRRSQSFNNYDKSKPVTSPPPPPSSHEKEPLASSASSHPGMSDNAPASLESGSSS 310 320 330 340 350 360 340 350 360 370 380 390 pF1KA1 TPTNCSTSSAIPQPGAATKPWRSKSLSVKHSATVSMLSVKPPGPEAPRPTPEAMKPAPNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TPTNCSTSSAIPQPGAATKPWRSKSLSVKHSATVSMLSVKPPGPEAPRPTPEAMKPAPNN 370 380 390 400 410 420 400 410 420 430 440 450 pF1KA1 QKSMLEKLKLFNSKGGSKAGEGPGSRDTSCERLETLPSFEESEELEAASRMLTTVGPASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QKSMLEKLKLFNSKGGSKAGEGPGSRDTSCERLETLPSFEESEELEAASRMLTTVGPASS 430 440 450 460 470 480 460 470 480 490 500 510 pF1KA1 SPKIALKGIAQRTFSRALTNKKSSLKGNEKEKEKQQREKDKEKSKDLAKRASVTERLDLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SPKIALKGIAQRTFSRALTNKKSSLKGNEKEKEKQQREKDKEKSKDLAKRASVTERLDLK 490 500 510 520 530 540 520 530 540 550 560 570 pF1KA1 EEPKEDPSGAAVPEMPKKSSKIASFIPKGGKLNSAKKEPMAPSHSGIPKPGMKSMPGKSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EEPKEDPSGAAVPEMPKKSSKIASFIPKGGKLNSAKKEPMAPSHSGIPKPGMKSMPGKSP 550 560 570 580 590 600 580 590 600 610 620 630 pF1KA1 SAPAPSKEGERSRSGKLSSGLPQQKPQLDGRHSSSSSSLASSEGKGPGGTTLNHSISSQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SAPAPSKEGERSRSGKLSSGLPQQKPQLDGRHSSSSSSLASSEGKGPGGTTLNHSISSQT 610 620 630 640 650 660 640 650 660 670 680 690 pF1KA1 VSGSVGTTQTTGSNTVSVQLPQPQQQYNHPNTATVAPFLYRSQTDTEGNVTAESSSTGVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VSGSVGTTQTTGSNTVSVQLPQPQQQYNHPNTATVAPFLYRSQTDTEGNVTAESSSTGVS 670 680 690 700 710 720 700 710 720 730 740 750 pF1KA1 VEPSHFTKTGQPALEELTGEDPEARRLRTVKNIADLRQNLEETMSSLRGTQVTHSTLETT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VEPSHFTKTGQPALEELTGEDPEARRLRTVKNIADLRQNLEETMSSLRGTQVTHSTLETT 730 740 750 760 770 780 760 770 780 790 800 810 pF1KA1 FDTNVTTEMSGRSILSLTGRPTPLSWRLGQSSPRLQAGDAPSMGNGYPPRANASRFINTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FDTNVTTEMSGRSILSLTGRPTPLSWRLGQSSPRLQAGDAPSMGNGYPPRANASRFINTE 790 800 810 820 830 840 820 830 840 850 860 870 pF1KA1 SGRYVYSAPLRRQLASRGSSVCHVDVSDKAGDEMDLEGISMDAPGYMSDGDVLSKNIRTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SGRYVYSAPLRRQLASRGSSVCHVDVSDKAGDEMDLEGISMDAPGYMSDGDVLSKNIRTD 850 860 870 880 890 900 880 890 900 910 920 930 pF1KA1 DITSGYMTDGGLGLYTRRLNRLPDGMAVVRETLQRNTSLGLGDADSWDDSSSVSSGISDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DITSGYMTDGGLGLYTRRLNRLPDGMAVVRETLQRNTSLGLGDADSWDDSSSVSSGISDT 910 920 930 940 950 960 940 950 960 970 980 990 pF1KA1 IDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNSLWSGDDVKKSDGGSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNSLWSGDDVKKSDGGSD 970 980 990 1000 1010 1020 1000 1010 1020 1030 1040 1050 pF1KA1 SGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGITMPRTKASAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::: XP_006 SGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGITMPRTKPSAP 1030 1040 1050 1060 1070 1080 1060 1070 1080 1090 1100 1110 pF1KA1 AGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDESKKPLPSSSRTPTANA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDESKKPLPSSSRTPTANA 1090 1100 1110 1120 1130 1140 1120 1130 1140 1150 1160 1170 pF1KA1 NSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSRSAGRKSSMDGAQNQDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSRSAGRKSSMDGAQNQDD 1150 1160 1170 1180 1190 1200 1180 1190 1200 1210 1220 1230 pF1KA1 GYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSKSAGLPVPKLREPSKTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSKSAGLPVPKLREPSKTA 1210 1220 1230 1240 1250 1260 1240 1250 1260 1270 1280 1290 pF1KA1 LGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVASP 1270 1280 1290 1300 1310 1320 1300 1310 1320 1330 1340 1350 pF1KA1 TLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSPSGSGVLSSGSSSPLYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSPSGSGVLSSGSSSPLYS 1330 1340 1350 1360 1370 1380 1360 1370 1380 1390 1400 1410 pF1KA1 KNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDIS 1390 1400 1410 1420 1430 1440 1420 1430 1440 1450 1460 1470 pF1KA1 LSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESPLSSPAASPKFCRSTLPRKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESPLSSPAASPKFCRSTLPRKQ 1450 1460 1470 1480 1490 1500 1480 1490 1500 1510 1520 1530 pF1KA1 DSDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DSDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSP 1510 1520 1530 1540 1550 1560 1540 1550 1560 1570 1580 1590 pF1KA1 SGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKSRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKSRT 1570 1580 1590 1600 1610 1620 1600 1610 1620 1630 1640 1650 pF1KA1 MSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRELDASQEKVSALTTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRELDASQEKVSALTTQ 1630 1640 1650 1660 1670 1680 1660 1670 1680 1690 1700 1710 pF1KA1 LTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAINGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAINGV 1690 1700 1710 1720 1730 1740 1720 1730 1740 1750 1760 1770 pF1KA1 INTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVGSNIESDSKKKKRKNWVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 INTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVGSNIESDSKKKKRKNWVN 1750 1760 1770 1780 1790 1800 1780 1790 1800 1810 1820 1830 pF1KA1 ELRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNGSTGSTPLLRNSHSNSLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ELRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNGSTGSTPLLRNSHSNSLI 1810 1820 1830 1840 1850 1860 1840 1850 1860 1870 1880 1890 pF1KA1 SECMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQLREAMNRMQSEIEKLKAEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SECMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQLREAMNRMQSEIEKLKAEN 1870 1880 1890 1900 1910 1920 1900 1910 1920 1930 1940 1950 pF1KA1 DRLKSESQGSGCSRAPSQVSISASPRQSMGLSQHSLNLTESTSLDMLLDDTGECSARKEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DRLKSESQGSGCSRAPSQVSISASPRQSMGLSQHSLNLTESTSLDMLLDDTGECSARKEG 1930 1940 1950 1960 1970 1980 1960 1970 1980 1990 2000 2010 pF1KA1 GRHVKIVVSFQEEMKWKEDSRPHLFLIGCIGVSGKTKWDVLDGVVRRLFKEYIIHVDPVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GRHVKIVVSFQEEMKWKEDSRPHLFLIGCIGVSGKTKWDVLDGVVRRLFKEYIIHVDPVS 1990 2000 2010 2020 2030 2040 2020 2030 2040 2050 2060 2070 pF1KA1 QLGLNSDSVLGYSIGEIKRSNTSETPELLPCGYLVGENTTISVTVKGLAENSLDSLVFES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QLGLNSDSVLGYSIGEIKRSNTSETPELLPCGYLVGENTTISVTVKGLAENSLDSLVFES 2050 2060 2070 2080 2090 2100 2080 2090 2100 2110 2120 2130 pF1KA1 LIPKPILQRYVSLLIEHRRIILSGPSGTGKTYLANRLSEYIVLREGRELTDGVIATFNVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LIPKPILQRYVSLLIEHRRIILSGPSGTGKTYLANRLSEYIVLREGRELTDGVIATFNVD 2110 2120 2130 2140 2150 2160 2140 2150 2160 2170 2180 2190 pF1KA1 HKSSKELRQYLSNLADQCNSENNAVDMPLVIILDNLHHVSSLGEIFNGLLNCKYHKCPYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HKSSKELRQYLSNLADQCNSENNAVDMPLVIILDNLHHVSSLGEIFNGLLNCKYHKCPYI 2170 2180 2190 2200 2210 2220 2200 2210 2220 2230 2240 2250 pF1KA1 IGTMNQATSSTPNLQLHHNFRWVLCANHTEPVKGFLGRFLRRKLMETEISGRVRNMELVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IGTMNQATSSTPNLQLHHNFRWVLCANHTEPVKGFLGRFLRRKLMETEISGRVRNMELVK 2230 2240 2250 2260 2270 2280 2260 2270 2280 2290 2300 2310 pF1KA1 IIDWIPKVWHHLNRFLEAHSSSDVTIGPRLFLSCPIDVDGSRVWFTDLWNYSIIPYLLEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IIDWIPKVWHHLNRFLEAHSSSDVTIGPRLFLSCPIDVDGSRVWFTDLWNYSIIPYLLEA 2290 2300 2310 2320 2330 2340 2320 2330 2340 2350 2360 2370 pF1KA1 VREGLQLYGRRAPWEDPAKWVMDTYPWAASPQQHEWPPLLQLRPEDVGFDGYSMPREGST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VREGLQLYGRRAPWEDPAKWVMDTYPWAASPQQHEWPPLLQLRPEDVGFDGYSMPREGST 2350 2360 2370 2380 2390 2400 2380 2390 2400 2410 2420 2430 pF1KA1 SKQMPPSDAEGDPLMNMLMRLQEAANYSSPQSYDSDSNSNSHHDDILDSSLESTL ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SKQMPPSDAEGDPLMNMLMRLQEAANYSSPQSYDSDSNSNSHHDDILDSSLESTL 2410 2420 2430 2440 2450 >>XP_011518748 (OMIM: 607026) PREDICTED: neuron navigato (2452 aa) initn: 11533 init1: 9767 opt: 14114 Z-score: 6504.4 bits: 1217.6 E(85289): 0 Smith-Waterman score: 15752; 98.9% identity (98.9% similar) in 2455 aa overlap (1-2432:1-2452) 10 20 30 40 50 60 pF1KA1 MPAILVASKMKSGLPKPVHSAAPILHVPPARAGPQPCYLKLGSKVEVSKTTYPSQIPLKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MPAILVASKMKSGLPKPVHSAAPILHVPPARAGPQPCYLKLGSKVEVSKTTYPSQIPLKS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 QVLQGLQEPAGEGLPLRKSGSVENGFDTQIYTDWANHYLAKSGHKRLIRDLQQDVTDGVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QVLQGLQEPAGEGLPLRKSGSVENGFDTQIYTDWANHYLAKSGHKRLIRDLQQDVTDGVL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 LAQIIQVVANEKIEDINGCPKNRSQMIENIDACLNFLAAKGINIQGLSAEEIRNGNLKAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LAQIIQVVANEKIEDINGCPKNRSQMIENIDACLNFLAAKGINIQGLSAEEIRNGNLKAI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 LGLFFSLSRYKQQQQQPQKQHLSSPLPPAVSQVAGAPSQCQAGTPQQQVPVTPQAPCQPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LGLFFSLSRYKQQQQQPQKQHLSSPLPPAVSQVAGAPSQCQAGTPQQQVPVTPQAPCQPH 190 200 210 220 230 240 250 260 270 pF1KA1 QPAPHQQSKAQAEMQS-----------------------RLPGPTARVSAAGSEAKTRGG :::::::::::::::: ::::::::::::::::::::: XP_011 QPAPHQQSKAQAEMQSSASSKDSSQSKIIRFTLGQKKISRLPGPTARVSAAGSEAKTRGG 250 260 270 280 290 300 280 290 300 310 320 330 pF1KA1 STTANNRRSQSFNNYDKSKPVTSPPPPPSSHEKEPLASSASSHPGMSDNAPASLESGSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STTANNRRSQSFNNYDKSKPVTSPPPPPSSHEKEPLASSASSHPGMSDNAPASLESGSSS 310 320 330 340 350 360 340 350 360 370 380 390 pF1KA1 TPTNCSTSSAIPQPGAATKPWRSKSLSVKHSATVSMLSVKPPGPEAPRPTPEAMKPAPNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TPTNCSTSSAIPQPGAATKPWRSKSLSVKHSATVSMLSVKPPGPEAPRPTPEAMKPAPNN 370 380 390 400 410 420 400 410 420 430 440 450 pF1KA1 QKSMLEKLKLFNSKGGSKAGEGPGSRDTSCERLETLPSFEESEELEAASRMLTTVGPASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QKSMLEKLKLFNSKGGSKAGEGPGSRDTSCERLETLPSFEESEELEAASRMLTTVGPASS 430 440 450 460 470 480 460 470 480 490 500 510 pF1KA1 SPKIALKGIAQRTFSRALTNKKSSLKGNEKEKEKQQREKDKEKSKDLAKRASVTERLDLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPKIALKGIAQRTFSRALTNKKSSLKGNEKEKEKQQREKDKEKSKDLAKRASVTERLDLK 490 500 510 520 530 540 520 530 540 550 560 570 pF1KA1 EEPKEDPSGAAVPEMPKKSSKIASFIPKGGKLNSAKKEPMAPSHSGIPKPGMKSMPGKSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEPKEDPSGAAVPEMPKKSSKIASFIPKGGKLNSAKKEPMAPSHSGIPKPGMKSMPGKSP 550 560 570 580 590 600 580 590 600 610 620 630 pF1KA1 SAPAPSKEGERSRSGKLSSGLPQQKPQLDGRHSSSSSSLASSEGKGPGGTTLNHSISSQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SAPAPSKEGERSRSGKLSSGLPQQKPQLDGRHSSSSSSLASSEGKGPGGTTLNHSISSQT 610 620 630 640 650 660 640 650 660 670 680 690 pF1KA1 VSGSVGTTQTTGSNTVSVQLPQPQQQYNHPNTATVAPFLYRSQTDTEGNVTAESSSTGVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSGSVGTTQTTGSNTVSVQLPQPQQQYNHPNTATVAPFLYRSQTDTEGNVTAESSSTGVS 670 680 690 700 710 720 700 710 720 730 740 750 pF1KA1 VEPSHFTKTGQPALEELTGEDPEARRLRTVKNIADLRQNLEETMSSLRGTQVTHSTLETT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VEPSHFTKTGQPALEELTGEDPEARRLRTVKNIADLRQNLEETMSSLRGTQVTHSTLETT 730 740 750 760 770 780 760 770 780 790 800 810 pF1KA1 FDTNVTTEMSGRSILSLTGRPTPLSWRLGQSSPRLQAGDAPSMGNGYPPRANASRFINTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FDTNVTTEMSGRSILSLTGRPTPLSWRLGQSSPRLQAGDAPSMGNGYPPRANASRFINTE 790 800 810 820 830 840 820 830 840 850 860 870 pF1KA1 SGRYVYSAPLRRQLASRGSSVCHVDVSDKAGDEMDLEGISMDAPGYMSDGDVLSKNIRTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGRYVYSAPLRRQLASRGSSVCHVDVSDKAGDEMDLEGISMDAPGYMSDGDVLSKNIRTD 850 860 870 880 890 900 880 890 900 910 920 930 pF1KA1 DITSGYMTDGGLGLYTRRLNRLPDGMAVVRETLQRNTSLGLGDADSWDDSSSVSSGISDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DITSGYMTDGGLGLYTRRLNRLPDGMAVVRETLQRNTSLGLGDADSWDDSSSVSSGISDT 910 920 930 940 950 960 940 950 960 970 980 990 pF1KA1 IDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNSLWSGDDVKKSDGGSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNSLWSGDDVKKSDGGSD 970 980 990 1000 1010 1020 1000 1010 1020 1030 1040 1050 pF1KA1 SGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGITMPRTKASAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::: XP_011 SGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGITMPRTKPSAP 1030 1040 1050 1060 1070 1080 1060 1070 1080 1090 1100 1110 pF1KA1 AGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDESKKPLPSSSRTPTANA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDESKKPLPSSSRTPTANA 1090 1100 1110 1120 1130 1140 1120 1130 1140 1150 1160 1170 pF1KA1 NSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSRSAGRKSSMDGAQNQDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSRSAGRKSSMDGAQNQDD 1150 1160 1170 1180 1190 1200 1180 1190 1200 1210 1220 1230 pF1KA1 GYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSKSAGLPVPKLREPSKTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSKSAGLPVPKLREPSKTA 1210 1220 1230 1240 1250 1260 1240 1250 1260 1270 1280 1290 pF1KA1 LGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVASP 1270 1280 1290 1300 1310 1320 1300 1310 1320 1330 1340 1350 pF1KA1 TLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSPSGSGVLSSGSSSPLYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSPSGSGVLSSGSSSPLYS 1330 1340 1350 1360 1370 1380 1360 1370 1380 1390 1400 1410 pF1KA1 KNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDIS 1390 1400 1410 1420 1430 1440 1420 1430 1440 1450 1460 1470 pF1KA1 LSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESPLSSPAASPKFCRSTLPRKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESPLSSPAASPKFCRSTLPRKQ 1450 1460 1470 1480 1490 1500 1480 1490 1500 1510 1520 1530 pF1KA1 DSDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DSDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSP 1510 1520 1530 1540 1550 1560 1540 1550 1560 1570 1580 1590 pF1KA1 SGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKSRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKSRT 1570 1580 1590 1600 1610 1620 1600 1610 1620 1630 1640 1650 pF1KA1 MSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRELDASQEKVSALTTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRELDASQEKVSALTTQ 1630 1640 1650 1660 1670 1680 1660 1670 1680 1690 1700 1710 pF1KA1 LTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAINGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAINGV 1690 1700 1710 1720 1730 1740 1720 1730 1740 1750 1760 1770 pF1KA1 INTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVGSNIESDSKKKKRKNWVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 INTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVGSNIESDSKKKKRKNW-- 1750 1760 1770 1780 1790 1780 1790 1800 1810 1820 1830 pF1KA1 ELRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNGSTGSTPLLRNSHSNSLI ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 -LRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNGSTGSTPLLRNSHSNSLI 1800 1810 1820 1830 1840 1850 1840 1850 1860 1870 1880 1890 pF1KA1 SECMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQLREAMNRMQSEIEKLKAEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SECMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQLREAMNRMQSEIEKLKAEN 1860 1870 1880 1890 1900 1910 1900 1910 1920 1930 1940 1950 pF1KA1 DRLKSESQGSGCSRAPSQVSISASPRQSMGLSQHSLNLTESTSLDMLLDDTGECSARKEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DRLKSESQGSGCSRAPSQVSISASPRQSMGLSQHSLNLTESTSLDMLLDDTGECSARKEG 1920 1930 1940 1950 1960 1970 1960 1970 1980 1990 2000 2010 pF1KA1 GRHVKIVVSFQEEMKWKEDSRPHLFLIGCIGVSGKTKWDVLDGVVRRLFKEYIIHVDPVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GRHVKIVVSFQEEMKWKEDSRPHLFLIGCIGVSGKTKWDVLDGVVRRLFKEYIIHVDPVS 1980 1990 2000 2010 2020 2030 2020 2030 2040 2050 2060 2070 pF1KA1 QLGLNSDSVLGYSIGEIKRSNTSETPELLPCGYLVGENTTISVTVKGLAENSLDSLVFES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QLGLNSDSVLGYSIGEIKRSNTSETPELLPCGYLVGENTTISVTVKGLAENSLDSLVFES 2040 2050 2060 2070 2080 2090 2080 2090 2100 2110 2120 2130 pF1KA1 LIPKPILQRYVSLLIEHRRIILSGPSGTGKTYLANRLSEYIVLREGRELTDGVIATFNVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LIPKPILQRYVSLLIEHRRIILSGPSGTGKTYLANRLSEYIVLREGRELTDGVIATFNVD 2100 2110 2120 2130 2140 2150 2140 2150 2160 2170 2180 2190 pF1KA1 HKSSKELRQYLSNLADQCNSENNAVDMPLVIILDNLHHVSSLGEIFNGLLNCKYHKCPYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HKSSKELRQYLSNLADQCNSENNAVDMPLVIILDNLHHVSSLGEIFNGLLNCKYHKCPYI 2160 2170 2180 2190 2200 2210 2200 2210 2220 2230 2240 2250 pF1KA1 IGTMNQATSSTPNLQLHHNFRWVLCANHTEPVKGFLGRFLRRKLMETEISGRVRNMELVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IGTMNQATSSTPNLQLHHNFRWVLCANHTEPVKGFLGRFLRRKLMETEISGRVRNMELVK 2220 2230 2240 2250 2260 2270 2260 2270 2280 2290 2300 2310 pF1KA1 IIDWIPKVWHHLNRFLEAHSSSDVTIGPRLFLSCPIDVDGSRVWFTDLWNYSIIPYLLEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IIDWIPKVWHHLNRFLEAHSSSDVTIGPRLFLSCPIDVDGSRVWFTDLWNYSIIPYLLEA 2280 2290 2300 2310 2320 2330 2320 2330 2340 2350 2360 2370 pF1KA1 VREGLQLYGRRAPWEDPAKWVMDTYPWAASPQQHEWPPLLQLRPEDVGFDGYSMPREGST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VREGLQLYGRRAPWEDPAKWVMDTYPWAASPQQHEWPPLLQLRPEDVGFDGYSMPREGST 2340 2350 2360 2370 2380 2390 2380 2390 2400 2410 2420 2430 pF1KA1 SKQMPPSDAEGDPLMNMLMRLQEAANYSSPQSYDSDSNSNSHHDDILDSSLESTL ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SKQMPPSDAEGDPLMNMLMRLQEAANYSSPQSYDSDSNSNSHHDDILDSSLESTL 2400 2410 2420 2430 2440 2450 >>XP_011518749 (OMIM: 607026) PREDICTED: neuron navigato (2451 aa) initn: 14871 init1: 7721 opt: 13098 Z-score: 6037.0 bits: 1131.1 E(85289): 0 Smith-Waterman score: 15369; 96.2% identity (96.2% similar) in 2488 aa overlap (1-2432:1-2451) 10 20 30 40 50 60 pF1KA1 MPAILVASKMKSGLPKPVHSAAPILHVPPARAGPQPCYLKLGSKVEVSKTTYPSQIPLKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MPAILVASKMKSGLPKPVHSAAPILHVPPARAGPQPCYLKLGSKVEVSKTTYPSQIPLKS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 QVLQGLQEPAGEGLPLRKSGSVENGFDTQIYTDWANHYLAKSGHKRLIRDLQQDVTDGVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QVLQGLQEPAGEGLPLRKSGSVENGFDTQIYTDWANHYLAKSGHKRLIRDLQQDVTDGVL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 LAQIIQVVANEKIEDINGCPKNRSQMIENIDACLNFLAAKGINIQGLSAEEIRNGNLKAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LAQIIQVVANEKIEDINGCPKNRSQMIENIDACLNFLAAKGINIQGLSAEEIRNGNLKAI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 LGLFFSLSRYKQQQQQPQKQHLSSPLPPAVSQVAGAPSQCQAGTPQQQVPVTPQAPCQPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LGLFFSLSRYKQQQQQPQKQHLSSPLPPAVSQVAGAPSQCQAGTPQQQVPVTPQAPCQPH 190 200 210 220 230 240 250 260 270 pF1KA1 QPAPHQQSKAQAEMQS-----------------------RLPGPTARVSAAGSEAKTRGG :::::::::::::::: ::::::::::::::::::::: XP_011 QPAPHQQSKAQAEMQSSASSKDSSQSKIIRFTLGQKKISRLPGPTARVSAAGSEAKTRGG 250 260 270 280 290 300 280 290 300 310 320 330 pF1KA1 STTANNRRSQSFNNYDKSKPVTSPPPPPSSHEKEPLASSASSHPGMSDNAPASLESGSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STTANNRRSQSFNNYDKSKPVTSPPPPPSSHEKEPLASSASSHPGMSDNAPASLESGSSS 310 320 330 340 350 360 340 350 360 370 380 390 pF1KA1 TPTNCSTSSAIPQPGAATKPWRSKSLSVKHSATVSMLSVKPPGPEAPRPTPEAMKPAPNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TPTNCSTSSAIPQPGAATKPWRSKSLSVKHSATVSMLSVKPPGPEAPRPTPEAMKPAPNN 370 380 390 400 410 420 400 410 420 430 440 450 pF1KA1 QKSMLEKLKLFNSKGGSKAGEGPGSRDTSCERLETLPSFEESEELEAASRMLTTVGPASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QKSMLEKLKLFNSKGGSKAGEGPGSRDTSCERLETLPSFEESEELEAASRMLTTVGPASS 430 440 450 460 470 480 460 470 480 490 500 510 pF1KA1 SPKIALKGIAQRTFSRALTNKKSSLKGNEKEKEKQQREKDKEKSKDLAKRASVTERLDLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPKIALKGIAQRTFSRALTNKKSSLKGNEKEKEKQQREKDKEKSKDLAKRASVTERLDLK 490 500 510 520 530 540 520 530 540 550 560 570 pF1KA1 EEPKEDPSGAAVPEMPKKSSKIASFIPKGGKLNSAKKEPMAPSHSGIPKPGMKSMPGKSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEPKEDPSGAAVPEMPKKSSKIASFIPKGGKLNSAKKEPMAPSHSGIPKPGMKSMPGKSP 550 560 570 580 590 600 580 590 600 610 620 630 pF1KA1 SAPAPSKEGERSRSGKLSSGLPQQKPQLDGRHSSSSSSLASSEGKGPGGTTLNHSISSQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SAPAPSKEGERSRSGKLSSGLPQQKPQLDGRHSSSSSSLASSEGKGPGGTTLNHSISSQT 610 620 630 640 650 660 640 650 660 670 680 690 pF1KA1 VSGSVGTTQTTGSNTVSVQLPQPQQQYNHPNTATVAPFLYRSQTDTEGNVTAESSSTGVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSGSVGTTQTTGSNTVSVQLPQPQQQYNHPNTATVAPFLYRSQTDTEGNVTAESSSTGVS 670 680 690 700 710 720 700 710 720 730 740 750 pF1KA1 VEPSHFTKTGQPALEELTGEDPEARRLRTVKNIADLRQNLEETMSSLRGTQVTHSTLETT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VEPSHFTKTGQPALEELTGEDPEARRLRTVKNIADLRQNLEETMSSLRGTQVTHSTLETT 730 740 750 760 770 780 760 770 780 790 800 810 pF1KA1 FDTNVTTEMSGRSILSLTGRPTPLSWRLGQSSPRLQAGDAPSMGNGYPPRANASRFINTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FDTNVTTEMSGRSILSLTGRPTPLSWRLGQSSPRLQAGDAPSMGNGYPPRANASRFINTE 790 800 810 820 830 840 820 830 840 850 860 870 pF1KA1 SGRYVYSAPLRRQLASRGSSVCHVDVSDKAGDEMDLEGISMDAPGYMSDGDVLSKNIRTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGRYVYSAPLRRQLASRGSSVCHVDVSDKAGDEMDLEGISMDAPGYMSDGDVLSKNIRTD 850 860 870 880 890 900 880 890 900 910 920 930 pF1KA1 DITSGYMTDGGLGLYTRRLNRLPDGMAVVRETLQRNTSLGLGDADSWDDSSSVSSGISDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DITSGYMTDGGLGLYTRRLNRLPDGMAVVRETLQRNTSLGLGDADSWDDSSSVSSGISDT 910 920 930 940 950 960 940 950 960 970 980 990 pF1KA1 IDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNSLWSGDDVKKSDGGSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNSLWSGDDVKKSDGGSD 970 980 990 1000 1010 1020 1000 1010 1020 1030 1040 1050 pF1KA1 SGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGITMPRTKASAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::: XP_011 SGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGITMPRTKPSAP 1030 1040 1050 1060 1070 1080 1060 1070 1080 1090 1100 1110 pF1KA1 AGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDESKKPLPSSSRTPTANA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDESKKPLPSSSRTPTANA 1090 1100 1110 1120 1130 1140 1120 1130 1140 1150 1160 1170 pF1KA1 NSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSRSAGRKSSMDGAQNQDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSRSAGRKSSMDGAQNQDD 1150 1160 1170 1180 1190 1200 1180 1190 1200 1210 1220 1230 pF1KA1 GYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSKSAGLPVPKLREPSKTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSKSAGLPVPKLREPSKTA 1210 1220 1230 1240 1250 1260 1240 1250 1260 1270 1280 1290 pF1KA1 LGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVASP 1270 1280 1290 1300 1310 1320 1300 1310 1320 1330 1340 1350 pF1KA1 TLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSPSGSGVLSSGSSSPLYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSPSGSGVLSSGSSSPLYS 1330 1340 1350 1360 1370 1380 1360 1370 1380 1390 1400 1410 pF1KA1 KNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDIS 1390 1400 1410 1420 1430 1440 1420 1430 1440 1450 1460 1470 pF1KA1 LSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESPLSSPAASPKFCRSTLPRKQ ::::::::::::::::::::::::::::::::::::::: XP_011 LSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSE--------------------- 1450 1460 1470 1480 1490 1500 1510 1520 1530 pF1KA1 DSDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSP :::::::::::::::::::::::::::::::::::::::::::: XP_011 ----------------RYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSP 1480 1490 1500 1510 1520 1540 1550 1560 1570 1580 1590 pF1KA1 SGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKSRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKSRT 1530 1540 1550 1560 1570 1580 1600 1610 1620 pF1KA1 MSRSGSFRDGFEE---------------------------------VHGSSLSLVSSTSS ::::::::::::: :::::::::::::: XP_011 MSRSGSFRDGFEEESWEKSSVDNFVSRLHSSLHFSLPLFHHARYELVHGSSLSLVSSTSS 1590 1600 1610 1620 1630 1640 1630 1640 1650 1660 1670 1680 pF1KA1 VYSTPEEKCQSEIRKLRRELDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VYSTPEEKCQSEIRKLRRELDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTM 1650 1660 1670 1680 1690 1700 1690 1700 1710 1720 1730 1740 pF1KA1 TAEQKDSELNELRKTIELLKKQNAAAQAAINGVINTPELNCKGNGTAQSADLRIRRQHSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TAEQKDSELNELRKTIELLKKQNAAAQAAINGVINTPELNCKGNGTAQSADLRIRRQHSS 1710 1720 1730 1740 1750 1760 1750 1760 1770 1780 1790 1800 pF1KA1 DSVSSINSATSHSSVGSNIESDSKKKKRKNWVNELRSSFKQAFGKKKSPKSASSHSDIEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DSVSSINSATSHSSVGSNIESDSKKKKRKNWVNELRSSFKQAFGKKKSPKSASSHSDIEE 1770 1780 1790 1800 1810 1820 1810 1820 1830 1840 1850 1860 pF1KA1 MTDSSLPSSPKLPHNGSTGSTPLLRNSHSNSLISECMDSEAETVMQLRNELRDKEMKLTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MTDSSLPSSPKLPHNGSTGSTPLLRNSHSNSLISECMDSEAETVMQLRNELRDKEMKLTD 1830 1840 1850 1860 1870 1880 1870 1880 1890 1900 1910 1920 pF1KA1 IRLEALSSAHQLDQLREAMNRMQSEIEKLKAENDRLKSESQGSGCSRAPSQVSISASPRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IRLEALSSAHQLDQLREAMNRMQSEIEKLKAENDRLKSESQGSGCSRAPSQVSISASPRQ 1890 1900 1910 1920 1930 1940 1930 1940 1950 1960 1970 1980 pF1KA1 SMGLSQHSLNLTESTSLDMLLDDTGECSARKEGGRHVKIVVSFQEEMKWKEDSRPHLFLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SMGLSQHSLNLTESTSLDMLLDDTGECSARKEGGRHVKIVVSFQEEMKWKEDSRPHLFLI 1950 1960 1970 1980 1990 2000 1990 2000 2010 2020 2030 2040 pF1KA1 GCIGVSGKTKWDVLDGVVRRLFKEYIIHVDPVSQLGLNSDSVLGYSIGEIKRSNTSETPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GCIGVSGKTKWDVLDGVVRRLFKEYIIHVDPVSQLGLNSDSVLGYSIGEIKRSNTSETPE 2010 2020 2030 2040 2050 2060 2050 2060 2070 2080 2090 2100 pF1KA1 LLPCGYLVGENTTISVTVKGLAENSLDSLVFESLIPKPILQRYVSLLIEHRRIILSGPSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLPCGYLVGENTTISVTVKGLAENSLDSLVFESLIPKPILQRYVSLLIEHRRIILSGPSG 2070 2080 2090 2100 2110 2120 2110 2120 2130 2140 2150 2160 pF1KA1 TGKTYLANRLSEYIVLREGRELTDGVIATFNVDHKSSKELRQYLSNLADQCNSENNAVDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TGKTYLANRLSEYIVLREGRELTDGVIATFNVDHKSSKELRQYLSNLADQCNSENNAVDM 2130 2140 2150 2160 2170 2180 2170 2180 2190 2200 2210 2220 pF1KA1 PLVIILDNLHHVSSLGEIFNGLLNCKYHKCPYIIGTMNQATSSTPNLQLHHNFRWVLCAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PLVIILDNLHHVSSLGEIFNGLLNCKYHKCPYIIGTMNQATSSTPNLQLHHNFRWVLCAN 2190 2200 2210 2220 2230 2240 2230 2240 2250 2260 2270 2280 pF1KA1 HTEPVKGFLGRFLRRKLMETEISGRVRNMELVKIIDWIPKVWHHLNRFLEAHSSSDVTIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HTEPVKGFLGRFLRRKLMETEISGRVRNMELVKIIDWIPKVWHHLNRFLEAHSSSDVTIG 2250 2260 2270 2280 2290 2300 2290 2300 2310 2320 2330 2340 pF1KA1 PRLFLSCPIDVDGSRVWFTDLWNYSIIPYLLEAVREGLQLYGRRAPWEDPAKWVMDTYPW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PRLFLSCPIDVDGSRVWFTDLWNYSIIPYLLEAVREGLQLYGRRAPWEDPAKWVMDTYPW 2310 2320 2330 2340 2350 2360 2350 2360 2370 2380 2390 2400 pF1KA1 AASPQQHEWPPLLQLRPEDVGFDGYSMPREGSTSKQMPPSDAEGDPLMNMLMRLQEAANY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AASPQQHEWPPLLQLRPEDVGFDGYSMPREGSTSKQMPPSDAEGDPLMNMLMRLQEAANY 2370 2380 2390 2400 2410 2420 2410 2420 2430 pF1KA1 SSPQSYDSDSNSNSHHDDILDSSLESTL :::::::::::::::::::::::::::: XP_011 SSPQSYDSDSNSNSHHDDILDSSLESTL 2430 2440 2450 >>XP_006718427 (OMIM: 607026) PREDICTED: neuron navigato (2465 aa) initn: 10459 init1: 10459 opt: 10459 Z-score: 4822.9 bits: 906.5 E(85289): 0 Smith-Waterman score: 15766; 98.6% identity (98.6% similar) in 2465 aa overlap (1-2432:1-2465) 10 20 30 40 50 60 pF1KA1 MPAILVASKMKSGLPKPVHSAAPILHVPPARAGPQPCYLKLGSKVEVSKTTYPSQIPLKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MPAILVASKMKSGLPKPVHSAAPILHVPPARAGPQPCYLKLGSKVEVSKTTYPSQIPLKS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 QVLQGLQEPAGEGLPLRKSGSVENGFDTQIYTDWANHYLAKSGHKRLIRDLQQDVTDGVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QVLQGLQEPAGEGLPLRKSGSVENGFDTQIYTDWANHYLAKSGHKRLIRDLQQDVTDGVL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 LAQIIQVVANEKIEDINGCPKNRSQMIENIDACLNFLAAKGINIQGLSAEEIRNGNLKAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LAQIIQVVANEKIEDINGCPKNRSQMIENIDACLNFLAAKGINIQGLSAEEIRNGNLKAI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 LGLFFSLSRYKQQQQQPQKQHLSSPLPPAVSQVAGAPSQCQAGTPQQQVPVTPQAPCQPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LGLFFSLSRYKQQQQQPQKQHLSSPLPPAVSQVAGAPSQCQAGTPQQQVPVTPQAPCQPH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 QPAPHQQSKAQAEMQSRLPGPTARVSAAGSEAKTRGGSTTANNRRSQSFNNYDKSKPVTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QPAPHQQSKAQAEMQSRLPGPTARVSAAGSEAKTRGGSTTANNRRSQSFNNYDKSKPVTS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 PPPPPSSHEKEPLASSASSHPGMSDNAPASLESGSSSTPTNCSTSSAIPQPGAATKPWRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PPPPPSSHEKEPLASSASSHPGMSDNAPASLESGSSSTPTNCSTSSAIPQPGAATKPWRS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 KSLSVKHSATVSMLSVKPPGPEAPRPTPEAMKPAPNNQKSMLEKLKLFNSKGGSKAGEGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KSLSVKHSATVSMLSVKPPGPEAPRPTPEAMKPAPNNQKSMLEKLKLFNSKGGSKAGEGP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 GSRDTSCERLETLPSFEESEELEAASRMLTTVGPASSSPKIALKGIAQRTFSRALTNKKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GSRDTSCERLETLPSFEESEELEAASRMLTTVGPASSSPKIALKGIAQRTFSRALTNKKS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 SLKGNEKEKEKQQREKDKEKSKDLAKRASVTERLDLKEEPKEDPSGAAVPEMPKKSSKIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SLKGNEKEKEKQQREKDKEKSKDLAKRASVTERLDLKEEPKEDPSGAAVPEMPKKSSKIA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 SFIPKGGKLNSAKKEPMAPSHSGIPKPGMKSMPGKSPSAPAPSKEGERSRSGKLSSGLPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SFIPKGGKLNSAKKEPMAPSHSGIPKPGMKSMPGKSPSAPAPSKEGERSRSGKLSSGLPQ 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 QKPQLDGRHSSSSSSLASSEGKGPGGTTLNHSISSQTVSGSVGTTQTTGSNTVSVQLPQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QKPQLDGRHSSSSSSLASSEGKGPGGTTLNHSISSQTVSGSVGTTQTTGSNTVSVQLPQP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 QQQYNHPNTATVAPFLYRSQTDTEGNVTAESSSTGVSVEPSHFTKTGQPALEELTGEDPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QQQYNHPNTATVAPFLYRSQTDTEGNVTAESSSTGVSVEPSHFTKTGQPALEELTGEDPE 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 ARRLRTVKNIADLRQNLEETMSSLRGTQVTHSTLETTFDTNVTTEMSGRSILSLTGRPTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ARRLRTVKNIADLRQNLEETMSSLRGTQVTHSTLETTFDTNVTTEMSGRSILSLTGRPTP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 LSWRLGQSSPRLQAGDAPSMGNGYPPRANASRFINTESGRYVYSAPLRRQLASRGSSVCH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LSWRLGQSSPRLQAGDAPSMGNGYPPRANASRFINTESGRYVYSAPLRRQLASRGSSVCH 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 VDVSDKAGDEMDLEGISMDAPGYMSDGDVLSKNIRTDDITSGYMTDGGLGLYTRRLNRLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VDVSDKAGDEMDLEGISMDAPGYMSDGDVLSKNIRTDDITSGYMTDGGLGLYTRRLNRLP 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 DGMAVVRETLQRNTSLGLGDADSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DGMAVVRETLQRNTSLGLGDADSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPA 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 SSRKNLDVQTDAEKHSQVERNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SSRKNLDVQTDAEKHSQVERNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESD 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA1 KSTSGKKNPVISQTGSWRRGMTAQVGITMPRTKASAPAGALKTPGTGKTDDAKVSEKGRL ::::::::::::::::::::::::::::::::: :::::::::::::::::::::::::: XP_006 KSTSGKKNPVISQTGSWRRGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRL 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA1 SPKASQVKRSPSDAGRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SPKASQVKRSPSDAGRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGV 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA1 TVTSRSATLGKIPKSSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TVTSRSATLGKIPKSSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSN 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA1 SRNGAGNRSSTSSIDSNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SRNGAGNRSSTSSIDSNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNE 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA1 SVASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SVASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMK 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA1 NSVVISNPHATMTQQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NSVVISNPHATMTQQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSN 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA1 SLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDS 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA1 LTPFVRTNSVKTTLSESPLSSPAASPKFCRSTLPRKQDSDPHLDRNTLPKKGLRYTPTSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LTPFVRTNSVKTTLSESPLSSPAASPKFCRSTLPRKQDSDPHLDRNTLPKKGLRYTPTSQ 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA1 LRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSN 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 pF1KA1 PTMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKSRTMSRSGSFRDGFEE---------- :::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PTMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKSRTMSRSGSFRDGFEEESWEKSSVDN 1570 1580 1590 1600 1610 1620 1620 1630 1640 pF1KA1 -----------------------VHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRELDAS ::::::::::::::::::::::::::::::::::::: XP_006 FVSRLHSSLHFSLPLFHHARYELVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRELDAS 1630 1640 1650 1660 1670 1680 1650 1660 1670 1680 1690 1700 pF1KA1 QEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELLKKQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELLKKQN 1690 1700 1710 1720 1730 1740 1710 1720 1730 1740 1750 1760 pF1KA1 AAAQAAINGVINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVGSNIESDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AAAQAAINGVINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVGSNIESDS 1750 1760 1770 1780 1790 1800 1770 1780 1790 1800 1810 1820 pF1KA1 KKKKRKNWVNELRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNGSTGSTPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KKKKRKNWVNELRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNGSTGSTPL 1810 1820 1830 1840 1850 1860 1830 1840 1850 1860 1870 1880 pF1KA1 LRNSHSNSLISECMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQLREAMNRMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LRNSHSNSLISECMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQLREAMNRMQ 1870 1880 1890 1900 1910 1920 1890 1900 1910 1920 1930 1940 pF1KA1 SEIEKLKAENDRLKSESQGSGCSRAPSQVSISASPRQSMGLSQHSLNLTESTSLDMLLDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SEIEKLKAENDRLKSESQGSGCSRAPSQVSISASPRQSMGLSQHSLNLTESTSLDMLLDD 1930 1940 1950 1960 1970 1980 1950 1960 1970 1980 1990 2000 pF1KA1 TGECSARKEGGRHVKIVVSFQEEMKWKEDSRPHLFLIGCIGVSGKTKWDVLDGVVRRLFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TGECSARKEGGRHVKIVVSFQEEMKWKEDSRPHLFLIGCIGVSGKTKWDVLDGVVRRLFK 1990 2000 2010 2020 2030 2040 2010 2020 2030 2040 2050 2060 pF1KA1 EYIIHVDPVSQLGLNSDSVLGYSIGEIKRSNTSETPELLPCGYLVGENTTISVTVKGLAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EYIIHVDPVSQLGLNSDSVLGYSIGEIKRSNTSETPELLPCGYLVGENTTISVTVKGLAE 2050 2060 2070 2080 2090 2100 2070 2080 2090 2100 2110 2120 pF1KA1 NSLDSLVFESLIPKPILQRYVSLLIEHRRIILSGPSGTGKTYLANRLSEYIVLREGRELT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NSLDSLVFESLIPKPILQRYVSLLIEHRRIILSGPSGTGKTYLANRLSEYIVLREGRELT 2110 2120 2130 2140 2150 2160 2130 2140 2150 2160 2170 2180 pF1KA1 DGVIATFNVDHKSSKELRQYLSNLADQCNSENNAVDMPLVIILDNLHHVSSLGEIFNGLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DGVIATFNVDHKSSKELRQYLSNLADQCNSENNAVDMPLVIILDNLHHVSSLGEIFNGLL 2170 2180 2190 2200 2210 2220 2190 2200 2210 2220 2230 2240 pF1KA1 NCKYHKCPYIIGTMNQATSSTPNLQLHHNFRWVLCANHTEPVKGFLGRFLRRKLMETEIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NCKYHKCPYIIGTMNQATSSTPNLQLHHNFRWVLCANHTEPVKGFLGRFLRRKLMETEIS 2230 2240 2250 2260 2270 2280 2250 2260 2270 2280 2290 2300 pF1KA1 GRVRNMELVKIIDWIPKVWHHLNRFLEAHSSSDVTIGPRLFLSCPIDVDGSRVWFTDLWN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GRVRNMELVKIIDWIPKVWHHLNRFLEAHSSSDVTIGPRLFLSCPIDVDGSRVWFTDLWN 2290 2300 2310 2320 2330 2340 2310 2320 2330 2340 2350 2360 pF1KA1 YSIIPYLLEAVREGLQLYGRRAPWEDPAKWVMDTYPWAASPQQHEWPPLLQLRPEDVGFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YSIIPYLLEAVREGLQLYGRRAPWEDPAKWVMDTYPWAASPQQHEWPPLLQLRPEDVGFD 2350 2360 2370 2380 2390 2400 2370 2380 2390 2400 2410 2420 pF1KA1 GYSMPREGSTSKQMPPSDAEGDPLMNMLMRLQEAANYSSPQSYDSDSNSNSHHDDILDSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GYSMPREGSTSKQMPPSDAEGDPLMNMLMRLQEAANYSSPQSYDSDSNSNSHHDDILDSS 2410 2420 2430 2440 2450 2460 2430 pF1KA1 LESTL ::::: XP_006 LESTL >>XP_016874011 (OMIM: 607026) PREDICTED: neuron navigato (2401 aa) initn: 9867 init1: 9867 opt: 9879 Z-score: 4556.2 bits: 857.1 E(85289): 0 Smith-Waterman score: 15186; 97.8% identity (98.1% similar) in 2400 aa overlap (68-2432:2-2401) 40 50 60 70 80 90 pF1KA1 YLKLGSKVEVSKTTYPSQIPLKSQVLQGLQEPAGEGLPLRKSGSVENGFDTQ--IYTDWA : ..:. .: : .:.. : :::::: XP_016 MESVSESSQQQKRKPVIHGLEDQKRIYTDWA 10 20 30 100 110 120 130 140 150 pF1KA1 NHYLAKSGHKRLIRDLQQDVTDGVLLAQIIQVVANEKIEDINGCPKNRSQMIENIDACLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NHYLAKSGHKRLIRDLQQDVTDGVLLAQIIQVVANEKIEDINGCPKNRSQMIENIDACLN 40 50 60 70 80 90 160 170 180 190 200 210 pF1KA1 FLAAKGINIQGLSAEEIRNGNLKAILGLFFSLSRYKQQQQQPQKQHLSSPLPPAVSQVAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FLAAKGINIQGLSAEEIRNGNLKAILGLFFSLSRYKQQQQQPQKQHLSSPLPPAVSQVAG 100 110 120 130 140 150 220 230 240 250 260 270 pF1KA1 APSQCQAGTPQQQVPVTPQAPCQPHQPAPHQQSKAQAEMQSRLPGPTARVSAAGSEAKTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APSQCQAGTPQQQVPVTPQAPCQPHQPAPHQQSKAQAEMQSRLPGPTARVSAAGSEAKTR 160 170 180 190 200 210 280 290 300 310 320 330 pF1KA1 GGSTTANNRRSQSFNNYDKSKPVTSPPPPPSSHEKEPLASSASSHPGMSDNAPASLESGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GGSTTANNRRSQSFNNYDKSKPVTSPPPPPSSHEKEPLASSASSHPGMSDNAPASLESGS 220 230 240 250 260 270 340 350 360 370 380 390 pF1KA1 SSTPTNCSTSSAIPQPGAATKPWRSKSLSVKHSATVSMLSVKPPGPEAPRPTPEAMKPAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSTPTNCSTSSAIPQPGAATKPWRSKSLSVKHSATVSMLSVKPPGPEAPRPTPEAMKPAP 280 290 300 310 320 330 400 410 420 430 440 450 pF1KA1 NNQKSMLEKLKLFNSKGGSKAGEGPGSRDTSCERLETLPSFEESEELEAASRMLTTVGPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NNQKSMLEKLKLFNSKGGSKAGEGPGSRDTSCERLETLPSFEESEELEAASRMLTTVGPA 340 350 360 370 380 390 460 470 480 490 500 510 pF1KA1 SSSPKIALKGIAQRTFSRALTNKKSSLKGNEKEKEKQQREKDKEKSKDLAKRASVTERLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSSPKIALKGIAQRTFSRALTNKKSSLKGNEKEKEKQQREKDKEKSKDLAKRASVTERLD 400 410 420 430 440 450 520 530 540 550 560 570 pF1KA1 LKEEPKEDPSGAAVPEMPKKSSKIASFIPKGGKLNSAKKEPMAPSHSGIPKPGMKSMPGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKEEPKEDPSGAAVPEMPKKSSKIASFIPKGGKLNSAKKEPMAPSHSGIPKPGMKSMPGK 460 470 480 490 500 510 580 590 600 610 620 630 pF1KA1 SPSAPAPSKEGERSRSGKLSSGLPQQKPQLDGRHSSSSSSLASSEGKGPGGTTLNHSISS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPSAPAPSKEGERSRSGKLSSGLPQQKPQLDGRHSSSSSSLASSEGKGPGGTTLNHSISS 520 530 540 550 560 570 640 650 660 670 680 690 pF1KA1 QTVSGSVGTTQTTGSNTVSVQLPQPQQQYNHPNTATVAPFLYRSQTDTEGNVTAESSSTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QTVSGSVGTTQTTGSNTVSVQLPQPQQQYNHPNTATVAPFLYRSQTDTEGNVTAESSSTG 580 590 600 610 620 630 700 710 720 730 740 750 pF1KA1 VSVEPSHFTKTGQPALEELTGEDPEARRLRTVKNIADLRQNLEETMSSLRGTQVTHSTLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VSVEPSHFTKTGQPALEELTGEDPEARRLRTVKNIADLRQNLEETMSSLRGTQVTHSTLE 640 650 660 670 680 690 760 770 780 790 800 810 pF1KA1 TTFDTNVTTEMSGRSILSLTGRPTPLSWRLGQSSPRLQAGDAPSMGNGYPPRANASRFIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TTFDTNVTTEMSGRSILSLTGRPTPLSWRLGQSSPRLQAGDAPSMGNGYPPRANASRFIN 700 710 720 730 740 750 820 830 840 850 860 870 pF1KA1 TESGRYVYSAPLRRQLASRGSSVCHVDVSDKAGDEMDLEGISMDAPGYMSDGDVLSKNIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TESGRYVYSAPLRRQLASRGSSVCHVDVSDKAGDEMDLEGISMDAPGYMSDGDVLSKNIR 760 770 780 790 800 810 880 890 900 910 920 930 pF1KA1 TDDITSGYMTDGGLGLYTRRLNRLPDGMAVVRETLQRNTSLGLGDADSWDDSSSVSSGIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TDDITSGYMTDGGLGLYTRRLNRLPDGMAVVRETLQRNTSLGLGDADSWDDSSSVSSGIS 820 830 840 850 860 870 940 950 960 970 980 990 pF1KA1 DTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNSLWSGDDVKKSDGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNSLWSGDDVKKSDGG 880 890 900 910 920 930 1000 1010 1020 1030 1040 1050 pF1KA1 SDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGITMPRTKAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: : XP_016 SDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGITMPRTKPS 940 950 960 970 980 990 1060 1070 1080 1090 1100 1110 pF1KA1 APAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDESKKPLPSSSRTPTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDESKKPLPSSSRTPTA 1000 1010 1020 1030 1040 1050 1120 1130 1140 1150 1160 1170 pF1KA1 NANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSRSAGRKSSMDGAQNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSRSAGRKSSMDGAQNQ 1060 1070 1080 1090 1100 1110 1180 1190 1200 1210 1220 1230 pF1KA1 DDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSKSAGLPVPKLREPSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSKSAGLPVPKLREPSK 1120 1130 1140 1150 1160 1170 1240 1250 1260 1270 1280 1290 pF1KA1 TALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVA 1180 1190 1200 1210 1220 1230 1300 1310 1320 1330 1340 1350 pF1KA1 SPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSPSGSGVLSSGSSSPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSPSGSGVLSSGSSSPL 1240 1250 1260 1270 1280 1290 1360 1370 1380 1390 1400 1410 pF1KA1 YSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESID 1300 1310 1320 1330 1340 1350 1420 1430 1440 1450 1460 1470 pF1KA1 ISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESPLSSPAASPKFCRSTLPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESPLSSPAASPKFCRSTLPR 1360 1370 1380 1390 1400 1410 1480 1490 1500 1510 1520 1530 pF1KA1 KQDSDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KQDSDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVT 1420 1430 1440 1450 1460 1470 1540 1550 1560 1570 1580 1590 pF1KA1 SPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKS 1480 1490 1500 1510 1520 1530 1600 1610 1620 pF1KA1 RTMSRSGSFRDGFEE---------------------------------VHGSSLSLVSST ::::::::::::::: :::::::::::: XP_016 RTMSRSGSFRDGFEEESWEKSSVDNFVSRLHSSLHFSLPLFHHARYELVHGSSLSLVSST 1540 1550 1560 1570 1580 1590 1630 1640 1650 1660 1670 1680 pF1KA1 SSVYSTPEEKCQSEIRKLRRELDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSVYSTPEEKCQSEIRKLRRELDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSL 1600 1610 1620 1630 1640 1650 1690 1700 1710 1720 1730 1740 pF1KA1 TMTAEQKDSELNELRKTIELLKKQNAAAQAAINGVINTPELNCKGNGTAQSADLRIRRQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TMTAEQKDSELNELRKTIELLKKQNAAAQAAINGVINTPELNCKGNGTAQSADLRIRRQH 1660 1670 1680 1690 1700 1710 1750 1760 1770 1780 1790 1800 pF1KA1 SSDSVSSINSATSHSSVGSNIESDSKKKKRKNWVNELRSSFKQAFGKKKSPKSASSHSDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSDSVSSINSATSHSSVGSNIESDSKKKKRKNWVNELRSSFKQAFGKKKSPKSASSHSDI 1720 1730 1740 1750 1760 1770 1810 1820 1830 1840 1850 1860 pF1KA1 EEMTDSSLPSSPKLPHNGSTGSTPLLRNSHSNSLISECMDSEAETVMQLRNELRDKEMKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEMTDSSLPSSPKLPHNGSTGSTPLLRNSHSNSLISECMDSEAETVMQLRNELRDKEMKL 1780 1790 1800 1810 1820 1830 1870 1880 1890 1900 1910 1920 pF1KA1 TDIRLEALSSAHQLDQLREAMNRMQSEIEKLKAENDRLKSESQGSGCSRAPSQVSISASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TDIRLEALSSAHQLDQLREAMNRMQSEIEKLKAENDRLKSESQGSGCSRAPSQVSISASP 1840 1850 1860 1870 1880 1890 1930 1940 1950 1960 1970 1980 pF1KA1 RQSMGLSQHSLNLTESTSLDMLLDDTGECSARKEGGRHVKIVVSFQEEMKWKEDSRPHLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RQSMGLSQHSLNLTESTSLDMLLDDTGECSARKEGGRHVKIVVSFQEEMKWKEDSRPHLF 1900 1910 1920 1930 1940 1950 1990 2000 2010 2020 2030 2040 pF1KA1 LIGCIGVSGKTKWDVLDGVVRRLFKEYIIHVDPVSQLGLNSDSVLGYSIGEIKRSNTSET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LIGCIGVSGKTKWDVLDGVVRRLFKEYIIHVDPVSQLGLNSDSVLGYSIGEIKRSNTSET 1960 1970 1980 1990 2000 2010 2050 2060 2070 2080 2090 2100 pF1KA1 PELLPCGYLVGENTTISVTVKGLAENSLDSLVFESLIPKPILQRYVSLLIEHRRIILSGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PELLPCGYLVGENTTISVTVKGLAENSLDSLVFESLIPKPILQRYVSLLIEHRRIILSGP 2020 2030 2040 2050 2060 2070 2110 2120 2130 2140 2150 2160 pF1KA1 SGTGKTYLANRLSEYIVLREGRELTDGVIATFNVDHKSSKELRQYLSNLADQCNSENNAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGTGKTYLANRLSEYIVLREGRELTDGVIATFNVDHKSSKELRQYLSNLADQCNSENNAV 2080 2090 2100 2110 2120 2130 2170 2180 2190 2200 2210 2220 pF1KA1 DMPLVIILDNLHHVSSLGEIFNGLLNCKYHKCPYIIGTMNQATSSTPNLQLHHNFRWVLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DMPLVIILDNLHHVSSLGEIFNGLLNCKYHKCPYIIGTMNQATSSTPNLQLHHNFRWVLC 2140 2150 2160 2170 2180 2190 2230 2240 2250 2260 2270 2280 pF1KA1 ANHTEPVKGFLGRFLRRKLMETEISGRVRNMELVKIIDWIPKVWHHLNRFLEAHSSSDVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ANHTEPVKGFLGRFLRRKLMETEISGRVRNMELVKIIDWIPKVWHHLNRFLEAHSSSDVT 2200 2210 2220 2230 2240 2250 2290 2300 2310 2320 2330 2340 pF1KA1 IGPRLFLSCPIDVDGSRVWFTDLWNYSIIPYLLEAVREGLQLYGRRAPWEDPAKWVMDTY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IGPRLFLSCPIDVDGSRVWFTDLWNYSIIPYLLEAVREGLQLYGRRAPWEDPAKWVMDTY 2260 2270 2280 2290 2300 2310 2350 2360 2370 2380 2390 2400 pF1KA1 PWAASPQQHEWPPLLQLRPEDVGFDGYSMPREGSTSKQMPPSDAEGDPLMNMLMRLQEAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PWAASPQQHEWPPLLQLRPEDVGFDGYSMPREGSTSKQMPPSDAEGDPLMNMLMRLQEAA 2320 2330 2340 2350 2360 2370 2410 2420 2430 pF1KA1 NYSSPQSYDSDSNSNSHHDDILDSSLESTL :::::::::::::::::::::::::::::: XP_016 NYSSPQSYDSDSNSNSHHDDILDSSLESTL 2380 2390 2400 >>XP_011518753 (OMIM: 607026) PREDICTED: neuron navigato (2395 aa) initn: 9868 init1: 9868 opt: 9868 Z-score: 4551.2 bits: 856.2 E(85289): 0 Smith-Waterman score: 15175; 98.4% identity (98.5% similar) in 2379 aa overlap (87-2432:17-2395) 60 70 80 90 100 110 pF1KA1 PLKSQVLQGLQEPAGEGLPLRKSGSVENGFDTQIYTDWANHYLAKSGHKRLIRDLQQDVT . .::::::::::::::::::::::::::: XP_011 MAIDLYCGLACLWGIHEPRIYTDWANHYLAKSGHKRLIRDLQQDVT 10 20 30 40 120 130 140 150 160 170 pF1KA1 DGVLLAQIIQVVANEKIEDINGCPKNRSQMIENIDACLNFLAAKGINIQGLSAEEIRNGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DGVLLAQIIQVVANEKIEDINGCPKNRSQMIENIDACLNFLAAKGINIQGLSAEEIRNGN 50 60 70 80 90 100 180 190 200 210 220 230 pF1KA1 LKAILGLFFSLSRYKQQQQQPQKQHLSSPLPPAVSQVAGAPSQCQAGTPQQQVPVTPQAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKAILGLFFSLSRYKQQQQQPQKQHLSSPLPPAVSQVAGAPSQCQAGTPQQQVPVTPQAP 110 120 130 140 150 160 240 250 260 270 280 290 pF1KA1 CQPHQPAPHQQSKAQAEMQSRLPGPTARVSAAGSEAKTRGGSTTANNRRSQSFNNYDKSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CQPHQPAPHQQSKAQAEMQSRLPGPTARVSAAGSEAKTRGGSTTANNRRSQSFNNYDKSK 170 180 190 200 210 220 300 310 320 330 340 350 pF1KA1 PVTSPPPPPSSHEKEPLASSASSHPGMSDNAPASLESGSSSTPTNCSTSSAIPQPGAATK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVTSPPPPPSSHEKEPLASSASSHPGMSDNAPASLESGSSSTPTNCSTSSAIPQPGAATK 230 240 250 260 270 280 360 370 380 390 400 410 pF1KA1 PWRSKSLSVKHSATVSMLSVKPPGPEAPRPTPEAMKPAPNNQKSMLEKLKLFNSKGGSKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PWRSKSLSVKHSATVSMLSVKPPGPEAPRPTPEAMKPAPNNQKSMLEKLKLFNSKGGSKA 290 300 310 320 330 340 420 430 440 450 460 470 pF1KA1 GEGPGSRDTSCERLETLPSFEESEELEAASRMLTTVGPASSSPKIALKGIAQRTFSRALT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GEGPGSRDTSCERLETLPSFEESEELEAASRMLTTVGPASSSPKIALKGIAQRTFSRALT 350 360 370 380 390 400 480 490 500 510 520 530 pF1KA1 NKKSSLKGNEKEKEKQQREKDKEKSKDLAKRASVTERLDLKEEPKEDPSGAAVPEMPKKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NKKSSLKGNEKEKEKQQREKDKEKSKDLAKRASVTERLDLKEEPKEDPSGAAVPEMPKKS 410 420 430 440 450 460 540 550 560 570 580 590 pF1KA1 SKIASFIPKGGKLNSAKKEPMAPSHSGIPKPGMKSMPGKSPSAPAPSKEGERSRSGKLSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SKIASFIPKGGKLNSAKKEPMAPSHSGIPKPGMKSMPGKSPSAPAPSKEGERSRSGKLSS 470 480 490 500 510 520 600 610 620 630 640 650 pF1KA1 GLPQQKPQLDGRHSSSSSSLASSEGKGPGGTTLNHSISSQTVSGSVGTTQTTGSNTVSVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLPQQKPQLDGRHSSSSSSLASSEGKGPGGTTLNHSISSQTVSGSVGTTQTTGSNTVSVQ 530 540 550 560 570 580 660 670 680 690 700 710 pF1KA1 LPQPQQQYNHPNTATVAPFLYRSQTDTEGNVTAESSSTGVSVEPSHFTKTGQPALEELTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPQPQQQYNHPNTATVAPFLYRSQTDTEGNVTAESSSTGVSVEPSHFTKTGQPALEELTG 590 600 610 620 630 640 720 730 740 750 760 770 pF1KA1 EDPEARRLRTVKNIADLRQNLEETMSSLRGTQVTHSTLETTFDTNVTTEMSGRSILSLTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EDPEARRLRTVKNIADLRQNLEETMSSLRGTQVTHSTLETTFDTNVTTEMSGRSILSLTG 650 660 670 680 690 700 780 790 800 810 820 830 pF1KA1 RPTPLSWRLGQSSPRLQAGDAPSMGNGYPPRANASRFINTESGRYVYSAPLRRQLASRGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RPTPLSWRLGQSSPRLQAGDAPSMGNGYPPRANASRFINTESGRYVYSAPLRRQLASRGS 710 720 730 740 750 760 840 850 860 870 880 890 pF1KA1 SVCHVDVSDKAGDEMDLEGISMDAPGYMSDGDVLSKNIRTDDITSGYMTDGGLGLYTRRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SVCHVDVSDKAGDEMDLEGISMDAPGYMSDGDVLSKNIRTDDITSGYMTDGGLGLYTRRL 770 780 790 800 810 820 900 910 920 930 940 950 pF1KA1 NRLPDGMAVVRETLQRNTSLGLGDADSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NRLPDGMAVVRETLQRNTSLGLGDADSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYA 830 840 850 860 870 880 960 970 980 990 1000 1010 pF1KA1 NTPASSRKNLDVQTDAEKHSQVERNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NTPASSRKNLDVQTDAEKHSQVERNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVS 890 900 910 920 930 940 1020 1030 1040 1050 1060 1070 pF1KA1 DESDKSTSGKKNPVISQTGSWRRGMTAQVGITMPRTKASAPAGALKTPGTGKTDDAKVSE ::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::: XP_011 DESDKSTSGKKNPVISQTGSWRRGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSE 950 960 970 980 990 1000 1080 1090 1100 1110 1120 1130 pF1KA1 KGRLSPKASQVKRSPSDAGRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KGRLSPKASQVKRSPSDAGRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMIT 1010 1020 1030 1040 1050 1060 1140 1150 1160 1170 1180 1190 pF1KA1 ASGVTVTSRSATLGKIPKSSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASGVTVTSRSATLGKIPKSSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRP 1070 1080 1090 1100 1110 1120 1200 1210 1220 1230 1240 1250 pF1KA1 SKSNSRNGAGNRSSTSSIDSNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SKSNSRNGAGNRSSTSSIDSNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGIS 1130 1140 1150 1160 1170 1180 1260 1270 1280 1290 1300 1310 pF1KA1 SDNESVASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SDNESVASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATA 1190 1200 1210 1220 1230 1240 1320 1330 1340 1350 1360 1370 pF1KA1 ENMKNSVVISNPHATMTQQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ENMKNSVVISNPHATMTQQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHS 1250 1260 1270 1280 1290 1300 1380 1390 1400 1410 1420 1430 pF1KA1 APSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASS 1310 1320 1330 1340 1350 1360 1440 1450 1460 1470 1480 1490 pF1KA1 KDDSLTPFVRTNSVKTTLSESPLSSPAASPKFCRSTLPRKQDSDPHLDRNTLPKKGLRYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KDDSLTPFVRTNSVKTTLSESPLSSPAASPKFCRSTLPRKQDSDPHLDRNTLPKKGLRYT 1370 1380 1390 1400 1410 1420 1500 1510 1520 1530 1540 1550 pF1KA1 PTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPSGTRFNFSQLASPTTVTQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPSGTRFNFSQLASPTTVTQM 1430 1440 1450 1460 1470 1480 1560 1570 1580 1590 1600 1610 pF1KA1 SLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKSRTMSRSGSFRDGFEE------ :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKSRTMSRSGSFRDGFEEESWEKS 1490 1500 1510 1520 1530 1540 1620 1630 1640 pF1KA1 ---------------------------VHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRE ::::::::::::::::::::::::::::::::: XP_011 SVDNFVSRLHSSLHFSLPLFHHARYELVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRE 1550 1560 1570 1580 1590 1600 1650 1660 1670 1680 1690 1700 pF1KA1 LDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELL 1610 1620 1630 1640 1650 1660 1710 1720 1730 1740 1750 1760 pF1KA1 KKQNAAAQAAINGVINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVGSNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KKQNAAAQAAINGVINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVGSNI 1670 1680 1690 1700 1710 1720 1770 1780 1790 1800 1810 1820 pF1KA1 ESDSKKKKRKNWVNELRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNGSTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ESDSKKKKRKNWVNELRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNGSTG 1730 1740 1750 1760 1770 1780 1830 1840 1850 1860 1870 1880 pF1KA1 STPLLRNSHSNSLISECMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQLREAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STPLLRNSHSNSLISECMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQLREAM 1790 1800 1810 1820 1830 1840 1890 1900 1910 1920 1930 1940 pF1KA1 NRMQSEIEKLKAENDRLKSESQGSGCSRAPSQVSISASPRQSMGLSQHSLNLTESTSLDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NRMQSEIEKLKAENDRLKSESQGSGCSRAPSQVSISASPRQSMGLSQHSLNLTESTSLDM 1850 1860 1870 1880 1890 1900 1950 1960 1970 1980 1990 2000 pF1KA1 LLDDTGECSARKEGGRHVKIVVSFQEEMKWKEDSRPHLFLIGCIGVSGKTKWDVLDGVVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLDDTGECSARKEGGRHVKIVVSFQEEMKWKEDSRPHLFLIGCIGVSGKTKWDVLDGVVR 1910 1920 1930 1940 1950 1960 2010 2020 2030 2040 2050 2060 pF1KA1 RLFKEYIIHVDPVSQLGLNSDSVLGYSIGEIKRSNTSETPELLPCGYLVGENTTISVTVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RLFKEYIIHVDPVSQLGLNSDSVLGYSIGEIKRSNTSETPELLPCGYLVGENTTISVTVK 1970 1980 1990 2000 2010 2020 2070 2080 2090 2100 2110 2120 pF1KA1 GLAENSLDSLVFESLIPKPILQRYVSLLIEHRRIILSGPSGTGKTYLANRLSEYIVLREG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLAENSLDSLVFESLIPKPILQRYVSLLIEHRRIILSGPSGTGKTYLANRLSEYIVLREG 2030 2040 2050 2060 2070 2080 2130 2140 2150 2160 2170 2180 pF1KA1 RELTDGVIATFNVDHKSSKELRQYLSNLADQCNSENNAVDMPLVIILDNLHHVSSLGEIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RELTDGVIATFNVDHKSSKELRQYLSNLADQCNSENNAVDMPLVIILDNLHHVSSLGEIF 2090 2100 2110 2120 2130 2140 2190 2200 2210 2220 2230 2240 pF1KA1 NGLLNCKYHKCPYIIGTMNQATSSTPNLQLHHNFRWVLCANHTEPVKGFLGRFLRRKLME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NGLLNCKYHKCPYIIGTMNQATSSTPNLQLHHNFRWVLCANHTEPVKGFLGRFLRRKLME 2150 2160 2170 2180 2190 2200 2250 2260 2270 2280 2290 2300 pF1KA1 TEISGRVRNMELVKIIDWIPKVWHHLNRFLEAHSSSDVTIGPRLFLSCPIDVDGSRVWFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TEISGRVRNMELVKIIDWIPKVWHHLNRFLEAHSSSDVTIGPRLFLSCPIDVDGSRVWFT 2210 2220 2230 2240 2250 2260 2310 2320 2330 2340 2350 2360 pF1KA1 DLWNYSIIPYLLEAVREGLQLYGRRAPWEDPAKWVMDTYPWAASPQQHEWPPLLQLRPED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DLWNYSIIPYLLEAVREGLQLYGRRAPWEDPAKWVMDTYPWAASPQQHEWPPLLQLRPED 2270 2280 2290 2300 2310 2320 2370 2380 2390 2400 2410 2420 pF1KA1 VGFDGYSMPREGSTSKQMPPSDAEGDPLMNMLMRLQEAANYSSPQSYDSDSNSNSHHDDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VGFDGYSMPREGSTSKQMPPSDAEGDPLMNMLMRLQEAANYSSPQSYDSDSNSNSHHDDI 2330 2340 2350 2360 2370 2380 2430 pF1KA1 LDSSLESTL ::::::::: XP_011 LDSSLESTL 2390 2432 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 20:03:18 2016 done: Thu Nov 3 20:03:22 2016 Total Scan time: 28.160 Total Display time: 2.130 Function used was FASTA [36.3.4 Apr, 2011]