FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1429, 1797 aa 1>>>pF1KA1429 1797 - 1797 aa - 1797 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 12.8147+/-0.00141; mu= -6.7236+/- 0.086 mean_var=496.8783+/-102.164, 0's: 0 Z-trim(113.2): 9 B-trim: 422 in 1/52 Lambda= 0.057537 statistics sampled from 13814 (13818) to 13814 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.701), E-opt: 0.2 (0.424), width: 16 Scan time: 6.430 The best scores are: opt bits E(32554) CCDS34923.1 KIAA1429 gene_id:25962|Hs108|chr8 (1812) 11094 937.2 0 CCDS47894.1 KIAA1429 gene_id:25962|Hs108|chr8 (1147) 7500 638.7 3.7e-182 >>CCDS34923.1 KIAA1429 gene_id:25962|Hs108|chr8 (1812 aa) initn: 11094 init1: 11094 opt: 11094 Z-score: 4993.5 bits: 937.2 E(32554): 0 Smith-Waterman score: 11094; 100.0% identity (100.0% similar) in 1683 aa overlap (1-1683:1-1683) 10 20 30 40 50 60 pF1KA1 MAVDSAMELLFLDTFKHPSAEQSSHIDVVRFPCVVYINEVRVIPPGVRAHSSLPDNRAYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 MAVDSAMELLFLDTFKHPSAEQSSHIDVVRFPCVVYINEVRVIPPGVRAHSSLPDNRAYG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 ETSPHTFQLDLFFNNVSKPSAPVFDRLGSLEYDENTSIIFRPNSKVNTDGLVLRGWYNCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 ETSPHTFQLDLFFNNVSKPSAPVFDRLGSLEYDENTSIIFRPNSKVNTDGLVLRGWYNCL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 TLAIYGSVDRVISHDRDSPPPPPPPPPPPQPQPSLKRNPKHADGEKEDQFNGSPPRPQPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 TLAIYGSVDRVISHDRDSPPPPPPPPPPPQPQPSLKRNPKHADGEKEDQFNGSPPRPQPR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 GPRTPPGPPPPDDDEDDPVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 GPRTPPGPPPPDDDEDDPVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 EEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEGDDGYEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 EEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEGDDGYEQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 ISSDEDGIADLERETFKYPNFDVEYTAEDLASVPPMTYDPYDRELVPLLYFSCPYKTTFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 ISSDEDGIADLERETFKYPNFDVEYTAEDLASVPPMTYDPYDRELVPLLYFSCPYKTTFE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 IEISRMKDQGPDKENSGAIEASVKLTELLDLYREDRGAKWVTALEEIPSLIIKGLSYLQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 IEISRMKDQGPDKENSGAIEASVKLTELLDLYREDRGAKWVTALEEIPSLIIKGLSYLQL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 KNTKQDSLGQLVDWTMQALNLQVALRQPIALNVRQLKAGTKLVSSLAECGAQGVTGLLQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 KNTKQDSLGQLVDWTMQALNLQVALRQPIALNVRQLKAGTKLVSSLAECGAQGVTGLLQA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 GVISGLFELLFADHVSSSLKLNAFKALDSVISMTEGMEAFLRGRQNEKSGYQKLLELILL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 GVISGLFELLFADHVSSSLKLNAFKALDSVISMTEGMEAFLRGRQNEKSGYQKLLELILL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 DQTVRVVTAGSAILQKCHFYEVLSEIKRLGDHLAEKTSSLPNHSEPDHDTDAGLERTNPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 DQTVRVVTAGSAILQKCHFYEVLSEIKRLGDHLAEKTSSLPNHSEPDHDTDAGLERTNPE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 YENEVEASMDMDLLESSNISEGEIERLINLLEEVFHLMETAPHTMIQQPVKSFPTMARIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 YENEVEASMDMDLLESSNISEGEIERLINLLEEVFHLMETAPHTMIQQPVKSFPTMARIT 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 GPPERDDPYPVLFRYLHSHHFLELVTLLLSIPVTSAHPGVLQATKDVLKFLAQSQKGLLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 GPPERDDPYPVLFRYLHSHHFLELVTLLLSIPVTSAHPGVLQATKDVLKFLAQSQKGLLF 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 FMSEYEATNLLIRALCHFYDQDEEEGLQSDGVIDDAFALWLQDSTQTLQCITELFSHFQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 FMSEYEATNLLIRALCHFYDQDEEEGLQSDGVIDDAFALWLQDSTQTLQCITELFSHFQR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 CTASEETDHSDLLGTLHNLYLITFNPVGRSAVGHVFSLEKNLQSLITLMEYYSKEALGDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 CTASEETDHSDLLGTLHNLYLITFNPVGRSAVGHVFSLEKNLQSLITLMEYYSKEALGDS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 KSKKSVAYNYACILILVVVQSSSDVQMLEQHAASLLKLCKADENNAKLQELGKWLEPLKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 KSKKSVAYNYACILILVVVQSSSDVQMLEQHAASLLKLCKADENNAKLQELGKWLEPLKN 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 LRFEINCIPNLIEYVKQNIDNLMTPEGVGLTTALRVLCNVACPPPPVEGQQKDLKWNLAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 LRFEINCIPNLIEYVKQNIDNLMTPEGVGLTTALRVLCNVACPPPPVEGQQKDLKWNLAV 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 IQLFSAEGMDTFIRVLQKLNSILTQPWRLHVNMGTTLHRVTTISMARCTLTLLKTMLTEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 IQLFSAEGMDTFIRVLQKLNSILTQPWRLHVNMGTTLHRVTTISMARCTLTLLKTMLTEL 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA1 LRGGSFEFKDMRVPSALVTLHMLLCSIPLSGRLDSDEQKIQNDIIDILLTFTQGVNEKLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 LRGGSFEFKDMRVPSALVTLHMLLCSIPLSGRLDSDEQKIQNDIIDILLTFTQGVNEKLT 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA1 ISEETLANNTWSLMLKEVLSSILKVPEGFFSGLILLSELLPLPLPMQTTQVIEPHDISVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 ISEETLANNTWSLMLKEVLSSILKVPEGFFSGLILLSELLPLPLPMQTTQVIEPHDISVA 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA1 LNTRKLWSMHLHVQAKLLQEIVRSFSGTTCQPIQHMLRRICVQLCDLASPTALLIMRTVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 LNTRKLWSMHLHVQAKLLQEIVRSFSGTTCQPIQHMLRRICVQLCDLASPTALLIMRTVL 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KA1 DLIVEDLQSTSEDKEKQYTSQTTRLLALLDALASHKACKLAILHLINGTIKGDERYAEIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 DLIVEDLQSTSEDKEKQYTSQTTRLLALLDALASHKACKLAILHLINGTIKGDERYAEIF 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KA1 QDLLALVRSPGDSVIRQQCVEYVTSILQSLCDQDIALILPSSSEGSISELEQLSNSLPNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 QDLLALVRSPGDSVIRQQCVEYVTSILQSLCDQDIALILPSSSEGSISELEQLSNSLPNK 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KA1 ELMTSICDCLLATLANSESSYNCLLTCVRTMMFLAEHDYGLFHLKSSLRKNSSALHSLLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 ELMTSICDCLLATLANSESSYNCLLTCVRTMMFLAEHDYGLFHLKSSLRKNSSALHSLLK 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KA1 RVVSTFSKDTGELASSFLEFMRQILNSDTIGCCGDDNGLMEVEGAHTSRTMSINAAELKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 RVVSTFSKDTGELASSFLEFMRQILNSDTIGCCGDDNGLMEVEGAHTSRTMSINAAELKQ 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KA1 LLQSKEESPENLFLELEKLVLEHSKDDDNLDSLLDSVVGLKQMLESSGDPLPLSDQDVEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 LLQSKEESPENLFLELEKLVLEHSKDDDNLDSLLDSVVGLKQMLESSGDPLPLSDQDVEP 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KA1 VLSAPESLQNLFNNRTAYVLADVMDDQLKSMWFTPFQAEEIDTDLDLVKVDLIELSEKCC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 VLSAPESLQNLFNNRTAYVLADVMDDQLKSMWFTPFQAEEIDTDLDLVKVDLIELSEKCC 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KA1 SDFDLHSELERSFLSEPSSPGRTKTTKGFKLGKHKHETFITSSGKSEYIEPAKRAHVVPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 SDFDLHSELERSFLSEPSSPGRTKTTKGFKLGKHKHETFITSSGKSEYIEPAKRAHVVPP 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KA1 PRGRGRGGFGQGIRPHDIFRQRKQNTSRPPSMHVDDFVAAESKEVVPQDGIPPPKRPLKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 PRGRGRGGFGQGIRPHDIFRQRKQNTSRPPSMHVDDFVAAESKEVVPQDGIPPPKRPLKV 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KA1 SQKEQEAPVGVLRILLEEITMKVVEARAILTEALFHHYDPLVLQVTAQVLGTVLLEVVGD ::: CCDS34 SQKISSRGGFSGNRGGRGAFHSQNRFFTPPASKGNYSRREGTRGSSWSAQNTPRGNYNES 1690 1700 1710 1720 1730 1740 >>CCDS47894.1 KIAA1429 gene_id:25962|Hs108|chr8 (1147 aa) initn: 7490 init1: 7490 opt: 7500 Z-score: 3383.8 bits: 638.7 E(32554): 3.7e-182 Smith-Waterman score: 7500; 99.6% identity (99.8% similar) in 1137 aa overlap (1-1137:1-1137) 10 20 30 40 50 60 pF1KA1 MAVDSAMELLFLDTFKHPSAEQSSHIDVVRFPCVVYINEVRVIPPGVRAHSSLPDNRAYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 MAVDSAMELLFLDTFKHPSAEQSSHIDVVRFPCVVYINEVRVIPPGVRAHSSLPDNRAYG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 ETSPHTFQLDLFFNNVSKPSAPVFDRLGSLEYDENTSIIFRPNSKVNTDGLVLRGWYNCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 ETSPHTFQLDLFFNNVSKPSAPVFDRLGSLEYDENTSIIFRPNSKVNTDGLVLRGWYNCL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 TLAIYGSVDRVISHDRDSPPPPPPPPPPPQPQPSLKRNPKHADGEKEDQFNGSPPRPQPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 TLAIYGSVDRVISHDRDSPPPPPPPPPPPQPQPSLKRNPKHADGEKEDQFNGSPPRPQPR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 GPRTPPGPPPPDDDEDDPVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 GPRTPPGPPPPDDDEDDPVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 EEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEGDDGYEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 EEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEGDDGYEQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 ISSDEDGIADLERETFKYPNFDVEYTAEDLASVPPMTYDPYDRELVPLLYFSCPYKTTFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 ISSDEDGIADLERETFKYPNFDVEYTAEDLASVPPMTYDPYDRELVPLLYFSCPYKTTFE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 IEISRMKDQGPDKENSGAIEASVKLTELLDLYREDRGAKWVTALEEIPSLIIKGLSYLQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 IEISRMKDQGPDKENSGAIEASVKLTELLDLYREDRGAKWVTALEEIPSLIIKGLSYLQL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 KNTKQDSLGQLVDWTMQALNLQVALRQPIALNVRQLKAGTKLVSSLAECGAQGVTGLLQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 KNTKQDSLGQLVDWTMQALNLQVALRQPIALNVRQLKAGTKLVSSLAECGAQGVTGLLQA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 GVISGLFELLFADHVSSSLKLNAFKALDSVISMTEGMEAFLRGRQNEKSGYQKLLELILL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 GVISGLFELLFADHVSSSLKLNAFKALDSVISMTEGMEAFLRGRQNEKSGYQKLLELILL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 DQTVRVVTAGSAILQKCHFYEVLSEIKRLGDHLAEKTSSLPNHSEPDHDTDAGLERTNPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 DQTVRVVTAGSAILQKCHFYEVLSEIKRLGDHLAEKTSSLPNHSEPDHDTDAGLERTNPE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 YENEVEASMDMDLLESSNISEGEIERLINLLEEVFHLMETAPHTMIQQPVKSFPTMARIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 YENEVEASMDMDLLESSNISEGEIERLINLLEEVFHLMETAPHTMIQQPVKSFPTMARIT 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 GPPERDDPYPVLFRYLHSHHFLELVTLLLSIPVTSAHPGVLQATKDVLKFLAQSQKGLLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 GPPERDDPYPVLFRYLHSHHFLELVTLLLSIPVTSAHPGVLQATKDVLKFLAQSQKGLLF 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 FMSEYEATNLLIRALCHFYDQDEEEGLQSDGVIDDAFALWLQDSTQTLQCITELFSHFQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 FMSEYEATNLLIRALCHFYDQDEEEGLQSDGVIDDAFALWLQDSTQTLQCITELFSHFQR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 CTASEETDHSDLLGTLHNLYLITFNPVGRSAVGHVFSLEKNLQSLITLMEYYSKEALGDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 CTASEETDHSDLLGTLHNLYLITFNPVGRSAVGHVFSLEKNLQSLITLMEYYSKEALGDS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 KSKKSVAYNYACILILVVVQSSSDVQMLEQHAASLLKLCKADENNAKLQELGKWLEPLKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 KSKKSVAYNYACILILVVVQSSSDVQMLEQHAASLLKLCKADENNAKLQELGKWLEPLKN 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 LRFEINCIPNLIEYVKQNIDNLMTPEGVGLTTALRVLCNVACPPPPVEGQQKDLKWNLAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 LRFEINCIPNLIEYVKQNIDNLMTPEGVGLTTALRVLCNVACPPPPVEGQQKDLKWNLAV 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 IQLFSAEGMDTFIRVLQKLNSILTQPWRLHVNMGTTLHRVTTISMARCTLTLLKTMLTEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 IQLFSAEGMDTFIRVLQKLNSILTQPWRLHVNMGTTLHRVTTISMARCTLTLLKTMLTEL 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA1 LRGGSFEFKDMRVPSALVTLHMLLCSIPLSGRLDSDEQKIQNDIIDILLTFTQGVNEKLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 LRGGSFEFKDMRVPSALVTLHMLLCSIPLSGRLDSDEQKIQNDIIDILLTFTQGVNEKLT 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KA1 ISEETLANNTWSLMLKEVLSSILKVPEGFFSGLILLSELLPLPLPMQTTQVIEPHDISVA ::::::::::::::::::::::::::::::::::::::::::::::::::: :... CCDS47 ISEETLANNTWSLMLKEVLSSILKVPEGFFSGLILLSELLPLPLPMQTTQVSLPYNMHLI 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KA1 LNTRKLWSMHLHVQAKLLQEIVRSFSGTTCQPIQHMLRRICVQLCDLASPTALLIMRTVL CCDS47 NDCSNTF 1797 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 06:13:02 2016 done: Thu Nov 3 06:13:03 2016 Total Scan time: 6.430 Total Display time: 0.200 Function used was FASTA [36.3.4 Apr, 2011]