FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1432, 791 aa 1>>>pF1KA1432 791 - 791 aa - 791 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7568+/-0.000365; mu= 18.8841+/- 0.023 mean_var=83.4293+/-16.912, 0's: 0 Z-trim(114.4): 11 B-trim: 0 in 0/50 Lambda= 0.140416 statistics sampled from 24207 (24218) to 24207 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.648), E-opt: 0.2 (0.284), width: 16 Scan time: 12.660 The best scores are: opt bits E(85289) XP_011516270 (OMIM: 610354) PREDICTED: RAB6A-GEF c ( 886) 5288 1081.6 0 XP_011516269 (OMIM: 610354) PREDICTED: RAB6A-GEF c (1112) 5288 1081.6 0 XP_016870423 (OMIM: 610354) PREDICTED: RAB6A-GEF c (1308) 5288 1081.7 0 XP_016870425 (OMIM: 610354) PREDICTED: RAB6A-GEF c (1308) 5288 1081.7 0 XP_016870424 (OMIM: 610354) PREDICTED: RAB6A-GEF c (1308) 5288 1081.7 0 NP_001193486 (OMIM: 610354) RAB6A-GEF complex part (1386) 5288 1081.7 0 XP_005251580 (OMIM: 610354) PREDICTED: RAB6A-GEF c (1422) 5288 1081.7 0 NP_065880 (OMIM: 610354) RAB6A-GEF complex partner (1423) 5288 1081.7 0 NP_001129392 (OMIM: 610354) RAB6A-GEF complex part (1165) 3422 703.6 1.2e-201 >>XP_011516270 (OMIM: 610354) PREDICTED: RAB6A-GEF compl (886 aa) initn: 5288 init1: 5288 opt: 5288 Z-score: 5785.8 bits: 1081.6 E(85289): 0 Smith-Waterman score: 5288; 100.0% identity (100.0% similar) in 791 aa overlap (1-791:96-886) 10 20 30 pF1KA1 MSRYIPHPFLVVSVTLTSVSTENGITLKMP :::::::::::::::::::::::::::::: XP_011 ADCSICLYSIERKSDGPNTTAGIQVLQEVSMSRYIPHPFLVVSVTLTSVSTENGITLKMP 70 80 90 100 110 120 40 50 60 70 80 90 pF1KA1 QQARGAESIMLNLAGQLIMMQRDRSGPQIREKDSNPNNQRKLLPFCPPVVLAQSVENVWT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QQARGAESIMLNLAGQLIMMQRDRSGPQIREKDSNPNNQRKLLPFCPPVVLAQSVENVWT 130 140 150 160 170 180 100 110 120 130 140 150 pF1KA1 TCRANKQKRHLLEALWLSCGGAGMKVWLPLFPRDHRKPHSFLSQRIMLPFHINIYPLAVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TCRANKQKRHLLEALWLSCGGAGMKVWLPLFPRDHRKPHSFLSQRIMLPFHINIYPLAVL 190 200 210 220 230 240 160 170 180 190 200 210 pF1KA1 FEDALVLGAVNDTLLYDSLYTRNNAREQLEVLFPFCVVERTSQIYLHHILRQLLVRNLGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FEDALVLGAVNDTLLYDSLYTRNNAREQLEVLFPFCVVERTSQIYLHHILRQLLVRNLGE 250 260 270 280 290 300 220 230 240 250 260 270 pF1KA1 QALLLAQSCATLPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QALLLAQSCATLPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVV 310 320 330 340 350 360 280 290 300 310 320 330 pF1KA1 HCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLL 370 380 390 400 410 420 340 350 360 370 380 390 pF1KA1 FNTALEQGKWDLCRHMIRFLKAIGSGESETPPSTPTAQEPSSSGGFEFFRNRSISLSQSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FNTALEQGKWDLCRHMIRFLKAIGSGESETPPSTPTAQEPSSSGGFEFFRNRSISLSQSA 430 440 450 460 470 480 400 410 420 430 440 450 pF1KA1 ENVPASKFSLQKTLSMPSGPSGKRWSKDSDCAENMYIDMMLWRHARRLLEDVRLKDLGCF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ENVPASKFSLQKTLSMPSGPSGKRWSKDSDCAENMYIDMMLWRHARRLLEDVRLKDLGCF 490 500 510 520 530 540 460 470 480 490 500 510 pF1KA1 AAQLGFELISWLCKERTRAARVDNFVIALKRLHKDFLWPLPIIPASSISSPFKNGKYRTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AAQLGFELISWLCKERTRAARVDNFVIALKRLHKDFLWPLPIIPASSISSPFKNGKYRTV 550 560 570 580 590 600 520 530 540 550 560 570 pF1KA1 GEQLLKSQSADPFLNLEMDAGISNIQRSQSWLSNIGPTHHEIDTASSHGPQMQDAFLSPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GEQLLKSQSADPFLNLEMDAGISNIQRSQSWLSNIGPTHHEIDTASSHGPQMQDAFLSPL 610 620 630 640 650 660 580 590 600 610 620 630 pF1KA1 SNKGDECSIGSATDLTESSSMVDGDWTMVDENFSTLSLTQSELEHISMELASKGPHKSQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SNKGDECSIGSATDLTESSSMVDGDWTMVDENFSTLSLTQSELEHISMELASKGPHKSQV 670 680 690 700 710 720 640 650 660 670 680 690 pF1KA1 QLRYLLHIFMEAGCLDWCIVIGLILRESSIINQILVITQSSEVDGEMLQNIKTGLHAVDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QLRYLLHIFMEAGCLDWCIVIGLILRESSIINQILVITQSSEVDGEMLQNIKTGLHAVDR 730 740 750 760 770 780 700 710 720 730 740 750 pF1KA1 WASTDCPGYKPFLNIIKPQLQKLSEITEEQVQPDAFQPITMGKTPEQTSPRAEESRGSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WASTDCPGYKPFLNIIKPQLQKLSEITEEQVQPDAFQPITMGKTPEQTSPRAEESRGSSS 790 800 810 820 830 840 760 770 780 790 pF1KA1 HGSIPQGEVGSSNMVSRKEEDTAQAEEEEPFQDGTYDCSVS ::::::::::::::::::::::::::::::::::::::::: XP_011 HGSIPQGEVGSSNMVSRKEEDTAQAEEEEPFQDGTYDCSVS 850 860 870 880 >>XP_011516269 (OMIM: 610354) PREDICTED: RAB6A-GEF compl (1112 aa) initn: 5288 init1: 5288 opt: 5288 Z-score: 5784.3 bits: 1081.6 E(85289): 0 Smith-Waterman score: 5288; 100.0% identity (100.0% similar) in 791 aa overlap (1-791:322-1112) 10 20 30 pF1KA1 MSRYIPHPFLVVSVTLTSVSTENGITLKMP :::::::::::::::::::::::::::::: XP_011 ADCSICLYSIERKSDGPNTTAGIQVLQEVSMSRYIPHPFLVVSVTLTSVSTENGITLKMP 300 310 320 330 340 350 40 50 60 70 80 90 pF1KA1 QQARGAESIMLNLAGQLIMMQRDRSGPQIREKDSNPNNQRKLLPFCPPVVLAQSVENVWT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QQARGAESIMLNLAGQLIMMQRDRSGPQIREKDSNPNNQRKLLPFCPPVVLAQSVENVWT 360 370 380 390 400 410 100 110 120 130 140 150 pF1KA1 TCRANKQKRHLLEALWLSCGGAGMKVWLPLFPRDHRKPHSFLSQRIMLPFHINIYPLAVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TCRANKQKRHLLEALWLSCGGAGMKVWLPLFPRDHRKPHSFLSQRIMLPFHINIYPLAVL 420 430 440 450 460 470 160 170 180 190 200 210 pF1KA1 FEDALVLGAVNDTLLYDSLYTRNNAREQLEVLFPFCVVERTSQIYLHHILRQLLVRNLGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FEDALVLGAVNDTLLYDSLYTRNNAREQLEVLFPFCVVERTSQIYLHHILRQLLVRNLGE 480 490 500 510 520 530 220 230 240 250 260 270 pF1KA1 QALLLAQSCATLPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QALLLAQSCATLPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVV 540 550 560 570 580 590 280 290 300 310 320 330 pF1KA1 HCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLL 600 610 620 630 640 650 340 350 360 370 380 390 pF1KA1 FNTALEQGKWDLCRHMIRFLKAIGSGESETPPSTPTAQEPSSSGGFEFFRNRSISLSQSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FNTALEQGKWDLCRHMIRFLKAIGSGESETPPSTPTAQEPSSSGGFEFFRNRSISLSQSA 660 670 680 690 700 710 400 410 420 430 440 450 pF1KA1 ENVPASKFSLQKTLSMPSGPSGKRWSKDSDCAENMYIDMMLWRHARRLLEDVRLKDLGCF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ENVPASKFSLQKTLSMPSGPSGKRWSKDSDCAENMYIDMMLWRHARRLLEDVRLKDLGCF 720 730 740 750 760 770 460 470 480 490 500 510 pF1KA1 AAQLGFELISWLCKERTRAARVDNFVIALKRLHKDFLWPLPIIPASSISSPFKNGKYRTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AAQLGFELISWLCKERTRAARVDNFVIALKRLHKDFLWPLPIIPASSISSPFKNGKYRTV 780 790 800 810 820 830 520 530 540 550 560 570 pF1KA1 GEQLLKSQSADPFLNLEMDAGISNIQRSQSWLSNIGPTHHEIDTASSHGPQMQDAFLSPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GEQLLKSQSADPFLNLEMDAGISNIQRSQSWLSNIGPTHHEIDTASSHGPQMQDAFLSPL 840 850 860 870 880 890 580 590 600 610 620 630 pF1KA1 SNKGDECSIGSATDLTESSSMVDGDWTMVDENFSTLSLTQSELEHISMELASKGPHKSQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SNKGDECSIGSATDLTESSSMVDGDWTMVDENFSTLSLTQSELEHISMELASKGPHKSQV 900 910 920 930 940 950 640 650 660 670 680 690 pF1KA1 QLRYLLHIFMEAGCLDWCIVIGLILRESSIINQILVITQSSEVDGEMLQNIKTGLHAVDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QLRYLLHIFMEAGCLDWCIVIGLILRESSIINQILVITQSSEVDGEMLQNIKTGLHAVDR 960 970 980 990 1000 1010 700 710 720 730 740 750 pF1KA1 WASTDCPGYKPFLNIIKPQLQKLSEITEEQVQPDAFQPITMGKTPEQTSPRAEESRGSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WASTDCPGYKPFLNIIKPQLQKLSEITEEQVQPDAFQPITMGKTPEQTSPRAEESRGSSS 1020 1030 1040 1050 1060 1070 760 770 780 790 pF1KA1 HGSIPQGEVGSSNMVSRKEEDTAQAEEEEPFQDGTYDCSVS ::::::::::::::::::::::::::::::::::::::::: XP_011 HGSIPQGEVGSSNMVSRKEEDTAQAEEEEPFQDGTYDCSVS 1080 1090 1100 1110 >>XP_016870423 (OMIM: 610354) PREDICTED: RAB6A-GEF compl (1308 aa) initn: 5288 init1: 5288 opt: 5288 Z-score: 5783.3 bits: 1081.7 E(85289): 0 Smith-Waterman score: 5288; 100.0% identity (100.0% similar) in 791 aa overlap (1-791:518-1308) 10 20 30 pF1KA1 MSRYIPHPFLVVSVTLTSVSTENGITLKMP :::::::::::::::::::::::::::::: XP_016 ADCSICLYSIERKSDGPNTTAGIQVLQEVSMSRYIPHPFLVVSVTLTSVSTENGITLKMP 490 500 510 520 530 540 40 50 60 70 80 90 pF1KA1 QQARGAESIMLNLAGQLIMMQRDRSGPQIREKDSNPNNQRKLLPFCPPVVLAQSVENVWT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QQARGAESIMLNLAGQLIMMQRDRSGPQIREKDSNPNNQRKLLPFCPPVVLAQSVENVWT 550 560 570 580 590 600 100 110 120 130 140 150 pF1KA1 TCRANKQKRHLLEALWLSCGGAGMKVWLPLFPRDHRKPHSFLSQRIMLPFHINIYPLAVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TCRANKQKRHLLEALWLSCGGAGMKVWLPLFPRDHRKPHSFLSQRIMLPFHINIYPLAVL 610 620 630 640 650 660 160 170 180 190 200 210 pF1KA1 FEDALVLGAVNDTLLYDSLYTRNNAREQLEVLFPFCVVERTSQIYLHHILRQLLVRNLGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FEDALVLGAVNDTLLYDSLYTRNNAREQLEVLFPFCVVERTSQIYLHHILRQLLVRNLGE 670 680 690 700 710 720 220 230 240 250 260 270 pF1KA1 QALLLAQSCATLPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QALLLAQSCATLPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVV 730 740 750 760 770 780 280 290 300 310 320 330 pF1KA1 HCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLL 790 800 810 820 830 840 340 350 360 370 380 390 pF1KA1 FNTALEQGKWDLCRHMIRFLKAIGSGESETPPSTPTAQEPSSSGGFEFFRNRSISLSQSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FNTALEQGKWDLCRHMIRFLKAIGSGESETPPSTPTAQEPSSSGGFEFFRNRSISLSQSA 850 860 870 880 890 900 400 410 420 430 440 450 pF1KA1 ENVPASKFSLQKTLSMPSGPSGKRWSKDSDCAENMYIDMMLWRHARRLLEDVRLKDLGCF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ENVPASKFSLQKTLSMPSGPSGKRWSKDSDCAENMYIDMMLWRHARRLLEDVRLKDLGCF 910 920 930 940 950 960 460 470 480 490 500 510 pF1KA1 AAQLGFELISWLCKERTRAARVDNFVIALKRLHKDFLWPLPIIPASSISSPFKNGKYRTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AAQLGFELISWLCKERTRAARVDNFVIALKRLHKDFLWPLPIIPASSISSPFKNGKYRTV 970 980 990 1000 1010 1020 520 530 540 550 560 570 pF1KA1 GEQLLKSQSADPFLNLEMDAGISNIQRSQSWLSNIGPTHHEIDTASSHGPQMQDAFLSPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GEQLLKSQSADPFLNLEMDAGISNIQRSQSWLSNIGPTHHEIDTASSHGPQMQDAFLSPL 1030 1040 1050 1060 1070 1080 580 590 600 610 620 630 pF1KA1 SNKGDECSIGSATDLTESSSMVDGDWTMVDENFSTLSLTQSELEHISMELASKGPHKSQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SNKGDECSIGSATDLTESSSMVDGDWTMVDENFSTLSLTQSELEHISMELASKGPHKSQV 1090 1100 1110 1120 1130 1140 640 650 660 670 680 690 pF1KA1 QLRYLLHIFMEAGCLDWCIVIGLILRESSIINQILVITQSSEVDGEMLQNIKTGLHAVDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLRYLLHIFMEAGCLDWCIVIGLILRESSIINQILVITQSSEVDGEMLQNIKTGLHAVDR 1150 1160 1170 1180 1190 1200 700 710 720 730 740 750 pF1KA1 WASTDCPGYKPFLNIIKPQLQKLSEITEEQVQPDAFQPITMGKTPEQTSPRAEESRGSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WASTDCPGYKPFLNIIKPQLQKLSEITEEQVQPDAFQPITMGKTPEQTSPRAEESRGSSS 1210 1220 1230 1240 1250 1260 760 770 780 790 pF1KA1 HGSIPQGEVGSSNMVSRKEEDTAQAEEEEPFQDGTYDCSVS ::::::::::::::::::::::::::::::::::::::::: XP_016 HGSIPQGEVGSSNMVSRKEEDTAQAEEEEPFQDGTYDCSVS 1270 1280 1290 1300 >>XP_016870425 (OMIM: 610354) PREDICTED: RAB6A-GEF compl (1308 aa) initn: 5288 init1: 5288 opt: 5288 Z-score: 5783.3 bits: 1081.7 E(85289): 0 Smith-Waterman score: 5288; 100.0% identity (100.0% similar) in 791 aa overlap (1-791:518-1308) 10 20 30 pF1KA1 MSRYIPHPFLVVSVTLTSVSTENGITLKMP :::::::::::::::::::::::::::::: XP_016 ADCSICLYSIERKSDGPNTTAGIQVLQEVSMSRYIPHPFLVVSVTLTSVSTENGITLKMP 490 500 510 520 530 540 40 50 60 70 80 90 pF1KA1 QQARGAESIMLNLAGQLIMMQRDRSGPQIREKDSNPNNQRKLLPFCPPVVLAQSVENVWT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QQARGAESIMLNLAGQLIMMQRDRSGPQIREKDSNPNNQRKLLPFCPPVVLAQSVENVWT 550 560 570 580 590 600 100 110 120 130 140 150 pF1KA1 TCRANKQKRHLLEALWLSCGGAGMKVWLPLFPRDHRKPHSFLSQRIMLPFHINIYPLAVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TCRANKQKRHLLEALWLSCGGAGMKVWLPLFPRDHRKPHSFLSQRIMLPFHINIYPLAVL 610 620 630 640 650 660 160 170 180 190 200 210 pF1KA1 FEDALVLGAVNDTLLYDSLYTRNNAREQLEVLFPFCVVERTSQIYLHHILRQLLVRNLGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FEDALVLGAVNDTLLYDSLYTRNNAREQLEVLFPFCVVERTSQIYLHHILRQLLVRNLGE 670 680 690 700 710 720 220 230 240 250 260 270 pF1KA1 QALLLAQSCATLPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QALLLAQSCATLPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVV 730 740 750 760 770 780 280 290 300 310 320 330 pF1KA1 HCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLL 790 800 810 820 830 840 340 350 360 370 380 390 pF1KA1 FNTALEQGKWDLCRHMIRFLKAIGSGESETPPSTPTAQEPSSSGGFEFFRNRSISLSQSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FNTALEQGKWDLCRHMIRFLKAIGSGESETPPSTPTAQEPSSSGGFEFFRNRSISLSQSA 850 860 870 880 890 900 400 410 420 430 440 450 pF1KA1 ENVPASKFSLQKTLSMPSGPSGKRWSKDSDCAENMYIDMMLWRHARRLLEDVRLKDLGCF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ENVPASKFSLQKTLSMPSGPSGKRWSKDSDCAENMYIDMMLWRHARRLLEDVRLKDLGCF 910 920 930 940 950 960 460 470 480 490 500 510 pF1KA1 AAQLGFELISWLCKERTRAARVDNFVIALKRLHKDFLWPLPIIPASSISSPFKNGKYRTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AAQLGFELISWLCKERTRAARVDNFVIALKRLHKDFLWPLPIIPASSISSPFKNGKYRTV 970 980 990 1000 1010 1020 520 530 540 550 560 570 pF1KA1 GEQLLKSQSADPFLNLEMDAGISNIQRSQSWLSNIGPTHHEIDTASSHGPQMQDAFLSPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GEQLLKSQSADPFLNLEMDAGISNIQRSQSWLSNIGPTHHEIDTASSHGPQMQDAFLSPL 1030 1040 1050 1060 1070 1080 580 590 600 610 620 630 pF1KA1 SNKGDECSIGSATDLTESSSMVDGDWTMVDENFSTLSLTQSELEHISMELASKGPHKSQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SNKGDECSIGSATDLTESSSMVDGDWTMVDENFSTLSLTQSELEHISMELASKGPHKSQV 1090 1100 1110 1120 1130 1140 640 650 660 670 680 690 pF1KA1 QLRYLLHIFMEAGCLDWCIVIGLILRESSIINQILVITQSSEVDGEMLQNIKTGLHAVDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLRYLLHIFMEAGCLDWCIVIGLILRESSIINQILVITQSSEVDGEMLQNIKTGLHAVDR 1150 1160 1170 1180 1190 1200 700 710 720 730 740 750 pF1KA1 WASTDCPGYKPFLNIIKPQLQKLSEITEEQVQPDAFQPITMGKTPEQTSPRAEESRGSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WASTDCPGYKPFLNIIKPQLQKLSEITEEQVQPDAFQPITMGKTPEQTSPRAEESRGSSS 1210 1220 1230 1240 1250 1260 760 770 780 790 pF1KA1 HGSIPQGEVGSSNMVSRKEEDTAQAEEEEPFQDGTYDCSVS ::::::::::::::::::::::::::::::::::::::::: XP_016 HGSIPQGEVGSSNMVSRKEEDTAQAEEEEPFQDGTYDCSVS 1270 1280 1290 1300 >>XP_016870424 (OMIM: 610354) PREDICTED: RAB6A-GEF compl (1308 aa) initn: 5288 init1: 5288 opt: 5288 Z-score: 5783.3 bits: 1081.7 E(85289): 0 Smith-Waterman score: 5288; 100.0% identity (100.0% similar) in 791 aa overlap (1-791:518-1308) 10 20 30 pF1KA1 MSRYIPHPFLVVSVTLTSVSTENGITLKMP :::::::::::::::::::::::::::::: XP_016 ADCSICLYSIERKSDGPNTTAGIQVLQEVSMSRYIPHPFLVVSVTLTSVSTENGITLKMP 490 500 510 520 530 540 40 50 60 70 80 90 pF1KA1 QQARGAESIMLNLAGQLIMMQRDRSGPQIREKDSNPNNQRKLLPFCPPVVLAQSVENVWT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QQARGAESIMLNLAGQLIMMQRDRSGPQIREKDSNPNNQRKLLPFCPPVVLAQSVENVWT 550 560 570 580 590 600 100 110 120 130 140 150 pF1KA1 TCRANKQKRHLLEALWLSCGGAGMKVWLPLFPRDHRKPHSFLSQRIMLPFHINIYPLAVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TCRANKQKRHLLEALWLSCGGAGMKVWLPLFPRDHRKPHSFLSQRIMLPFHINIYPLAVL 610 620 630 640 650 660 160 170 180 190 200 210 pF1KA1 FEDALVLGAVNDTLLYDSLYTRNNAREQLEVLFPFCVVERTSQIYLHHILRQLLVRNLGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FEDALVLGAVNDTLLYDSLYTRNNAREQLEVLFPFCVVERTSQIYLHHILRQLLVRNLGE 670 680 690 700 710 720 220 230 240 250 260 270 pF1KA1 QALLLAQSCATLPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QALLLAQSCATLPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVV 730 740 750 760 770 780 280 290 300 310 320 330 pF1KA1 HCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLL 790 800 810 820 830 840 340 350 360 370 380 390 pF1KA1 FNTALEQGKWDLCRHMIRFLKAIGSGESETPPSTPTAQEPSSSGGFEFFRNRSISLSQSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FNTALEQGKWDLCRHMIRFLKAIGSGESETPPSTPTAQEPSSSGGFEFFRNRSISLSQSA 850 860 870 880 890 900 400 410 420 430 440 450 pF1KA1 ENVPASKFSLQKTLSMPSGPSGKRWSKDSDCAENMYIDMMLWRHARRLLEDVRLKDLGCF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ENVPASKFSLQKTLSMPSGPSGKRWSKDSDCAENMYIDMMLWRHARRLLEDVRLKDLGCF 910 920 930 940 950 960 460 470 480 490 500 510 pF1KA1 AAQLGFELISWLCKERTRAARVDNFVIALKRLHKDFLWPLPIIPASSISSPFKNGKYRTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AAQLGFELISWLCKERTRAARVDNFVIALKRLHKDFLWPLPIIPASSISSPFKNGKYRTV 970 980 990 1000 1010 1020 520 530 540 550 560 570 pF1KA1 GEQLLKSQSADPFLNLEMDAGISNIQRSQSWLSNIGPTHHEIDTASSHGPQMQDAFLSPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GEQLLKSQSADPFLNLEMDAGISNIQRSQSWLSNIGPTHHEIDTASSHGPQMQDAFLSPL 1030 1040 1050 1060 1070 1080 580 590 600 610 620 630 pF1KA1 SNKGDECSIGSATDLTESSSMVDGDWTMVDENFSTLSLTQSELEHISMELASKGPHKSQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SNKGDECSIGSATDLTESSSMVDGDWTMVDENFSTLSLTQSELEHISMELASKGPHKSQV 1090 1100 1110 1120 1130 1140 640 650 660 670 680 690 pF1KA1 QLRYLLHIFMEAGCLDWCIVIGLILRESSIINQILVITQSSEVDGEMLQNIKTGLHAVDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLRYLLHIFMEAGCLDWCIVIGLILRESSIINQILVITQSSEVDGEMLQNIKTGLHAVDR 1150 1160 1170 1180 1190 1200 700 710 720 730 740 750 pF1KA1 WASTDCPGYKPFLNIIKPQLQKLSEITEEQVQPDAFQPITMGKTPEQTSPRAEESRGSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WASTDCPGYKPFLNIIKPQLQKLSEITEEQVQPDAFQPITMGKTPEQTSPRAEESRGSSS 1210 1220 1230 1240 1250 1260 760 770 780 790 pF1KA1 HGSIPQGEVGSSNMVSRKEEDTAQAEEEEPFQDGTYDCSVS ::::::::::::::::::::::::::::::::::::::::: XP_016 HGSIPQGEVGSSNMVSRKEEDTAQAEEEEPFQDGTYDCSVS 1270 1280 1290 1300 >>NP_001193486 (OMIM: 610354) RAB6A-GEF complex partner (1386 aa) initn: 5288 init1: 5288 opt: 5288 Z-score: 5782.9 bits: 1081.7 E(85289): 0 Smith-Waterman score: 5288; 100.0% identity (100.0% similar) in 791 aa overlap (1-791:596-1386) 10 20 30 pF1KA1 MSRYIPHPFLVVSVTLTSVSTENGITLKMP :::::::::::::::::::::::::::::: NP_001 ADCSICLYSIERKSDGPNTTAGIQVLQEVSMSRYIPHPFLVVSVTLTSVSTENGITLKMP 570 580 590 600 610 620 40 50 60 70 80 90 pF1KA1 QQARGAESIMLNLAGQLIMMQRDRSGPQIREKDSNPNNQRKLLPFCPPVVLAQSVENVWT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QQARGAESIMLNLAGQLIMMQRDRSGPQIREKDSNPNNQRKLLPFCPPVVLAQSVENVWT 630 640 650 660 670 680 100 110 120 130 140 150 pF1KA1 TCRANKQKRHLLEALWLSCGGAGMKVWLPLFPRDHRKPHSFLSQRIMLPFHINIYPLAVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TCRANKQKRHLLEALWLSCGGAGMKVWLPLFPRDHRKPHSFLSQRIMLPFHINIYPLAVL 690 700 710 720 730 740 160 170 180 190 200 210 pF1KA1 FEDALVLGAVNDTLLYDSLYTRNNAREQLEVLFPFCVVERTSQIYLHHILRQLLVRNLGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FEDALVLGAVNDTLLYDSLYTRNNAREQLEVLFPFCVVERTSQIYLHHILRQLLVRNLGE 750 760 770 780 790 800 220 230 240 250 260 270 pF1KA1 QALLLAQSCATLPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QALLLAQSCATLPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVV 810 820 830 840 850 860 280 290 300 310 320 330 pF1KA1 HCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLL 870 880 890 900 910 920 340 350 360 370 380 390 pF1KA1 FNTALEQGKWDLCRHMIRFLKAIGSGESETPPSTPTAQEPSSSGGFEFFRNRSISLSQSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FNTALEQGKWDLCRHMIRFLKAIGSGESETPPSTPTAQEPSSSGGFEFFRNRSISLSQSA 930 940 950 960 970 980 400 410 420 430 440 450 pF1KA1 ENVPASKFSLQKTLSMPSGPSGKRWSKDSDCAENMYIDMMLWRHARRLLEDVRLKDLGCF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENVPASKFSLQKTLSMPSGPSGKRWSKDSDCAENMYIDMMLWRHARRLLEDVRLKDLGCF 990 1000 1010 1020 1030 1040 460 470 480 490 500 510 pF1KA1 AAQLGFELISWLCKERTRAARVDNFVIALKRLHKDFLWPLPIIPASSISSPFKNGKYRTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AAQLGFELISWLCKERTRAARVDNFVIALKRLHKDFLWPLPIIPASSISSPFKNGKYRTV 1050 1060 1070 1080 1090 1100 520 530 540 550 560 570 pF1KA1 GEQLLKSQSADPFLNLEMDAGISNIQRSQSWLSNIGPTHHEIDTASSHGPQMQDAFLSPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GEQLLKSQSADPFLNLEMDAGISNIQRSQSWLSNIGPTHHEIDTASSHGPQMQDAFLSPL 1110 1120 1130 1140 1150 1160 580 590 600 610 620 630 pF1KA1 SNKGDECSIGSATDLTESSSMVDGDWTMVDENFSTLSLTQSELEHISMELASKGPHKSQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SNKGDECSIGSATDLTESSSMVDGDWTMVDENFSTLSLTQSELEHISMELASKGPHKSQV 1170 1180 1190 1200 1210 1220 640 650 660 670 680 690 pF1KA1 QLRYLLHIFMEAGCLDWCIVIGLILRESSIINQILVITQSSEVDGEMLQNIKTGLHAVDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLRYLLHIFMEAGCLDWCIVIGLILRESSIINQILVITQSSEVDGEMLQNIKTGLHAVDR 1230 1240 1250 1260 1270 1280 700 710 720 730 740 750 pF1KA1 WASTDCPGYKPFLNIIKPQLQKLSEITEEQVQPDAFQPITMGKTPEQTSPRAEESRGSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WASTDCPGYKPFLNIIKPQLQKLSEITEEQVQPDAFQPITMGKTPEQTSPRAEESRGSSS 1290 1300 1310 1320 1330 1340 760 770 780 790 pF1KA1 HGSIPQGEVGSSNMVSRKEEDTAQAEEEEPFQDGTYDCSVS ::::::::::::::::::::::::::::::::::::::::: NP_001 HGSIPQGEVGSSNMVSRKEEDTAQAEEEEPFQDGTYDCSVS 1350 1360 1370 1380 >>XP_005251580 (OMIM: 610354) PREDICTED: RAB6A-GEF compl (1422 aa) initn: 5288 init1: 5288 opt: 5288 Z-score: 5782.8 bits: 1081.7 E(85289): 0 Smith-Waterman score: 5288; 100.0% identity (100.0% similar) in 791 aa overlap (1-791:632-1422) 10 20 30 pF1KA1 MSRYIPHPFLVVSVTLTSVSTENGITLKMP :::::::::::::::::::::::::::::: XP_005 ADCSICLYSIERKSDGPNTTAGIQVLQEVSMSRYIPHPFLVVSVTLTSVSTENGITLKMP 610 620 630 640 650 660 40 50 60 70 80 90 pF1KA1 QQARGAESIMLNLAGQLIMMQRDRSGPQIREKDSNPNNQRKLLPFCPPVVLAQSVENVWT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QQARGAESIMLNLAGQLIMMQRDRSGPQIREKDSNPNNQRKLLPFCPPVVLAQSVENVWT 670 680 690 700 710 720 100 110 120 130 140 150 pF1KA1 TCRANKQKRHLLEALWLSCGGAGMKVWLPLFPRDHRKPHSFLSQRIMLPFHINIYPLAVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TCRANKQKRHLLEALWLSCGGAGMKVWLPLFPRDHRKPHSFLSQRIMLPFHINIYPLAVL 730 740 750 760 770 780 160 170 180 190 200 210 pF1KA1 FEDALVLGAVNDTLLYDSLYTRNNAREQLEVLFPFCVVERTSQIYLHHILRQLLVRNLGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FEDALVLGAVNDTLLYDSLYTRNNAREQLEVLFPFCVVERTSQIYLHHILRQLLVRNLGE 790 800 810 820 830 840 220 230 240 250 260 270 pF1KA1 QALLLAQSCATLPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QALLLAQSCATLPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVV 850 860 870 880 890 900 280 290 300 310 320 330 pF1KA1 HCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLL 910 920 930 940 950 960 340 350 360 370 380 390 pF1KA1 FNTALEQGKWDLCRHMIRFLKAIGSGESETPPSTPTAQEPSSSGGFEFFRNRSISLSQSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FNTALEQGKWDLCRHMIRFLKAIGSGESETPPSTPTAQEPSSSGGFEFFRNRSISLSQSA 970 980 990 1000 1010 1020 400 410 420 430 440 450 pF1KA1 ENVPASKFSLQKTLSMPSGPSGKRWSKDSDCAENMYIDMMLWRHARRLLEDVRLKDLGCF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ENVPASKFSLQKTLSMPSGPSGKRWSKDSDCAENMYIDMMLWRHARRLLEDVRLKDLGCF 1030 1040 1050 1060 1070 1080 460 470 480 490 500 510 pF1KA1 AAQLGFELISWLCKERTRAARVDNFVIALKRLHKDFLWPLPIIPASSISSPFKNGKYRTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AAQLGFELISWLCKERTRAARVDNFVIALKRLHKDFLWPLPIIPASSISSPFKNGKYRTV 1090 1100 1110 1120 1130 1140 520 530 540 550 560 570 pF1KA1 GEQLLKSQSADPFLNLEMDAGISNIQRSQSWLSNIGPTHHEIDTASSHGPQMQDAFLSPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GEQLLKSQSADPFLNLEMDAGISNIQRSQSWLSNIGPTHHEIDTASSHGPQMQDAFLSPL 1150 1160 1170 1180 1190 1200 580 590 600 610 620 630 pF1KA1 SNKGDECSIGSATDLTESSSMVDGDWTMVDENFSTLSLTQSELEHISMELASKGPHKSQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SNKGDECSIGSATDLTESSSMVDGDWTMVDENFSTLSLTQSELEHISMELASKGPHKSQV 1210 1220 1230 1240 1250 1260 640 650 660 670 680 690 pF1KA1 QLRYLLHIFMEAGCLDWCIVIGLILRESSIINQILVITQSSEVDGEMLQNIKTGLHAVDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QLRYLLHIFMEAGCLDWCIVIGLILRESSIINQILVITQSSEVDGEMLQNIKTGLHAVDR 1270 1280 1290 1300 1310 1320 700 710 720 730 740 750 pF1KA1 WASTDCPGYKPFLNIIKPQLQKLSEITEEQVQPDAFQPITMGKTPEQTSPRAEESRGSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WASTDCPGYKPFLNIIKPQLQKLSEITEEQVQPDAFQPITMGKTPEQTSPRAEESRGSSS 1330 1340 1350 1360 1370 1380 760 770 780 790 pF1KA1 HGSIPQGEVGSSNMVSRKEEDTAQAEEEEPFQDGTYDCSVS ::::::::::::::::::::::::::::::::::::::::: XP_005 HGSIPQGEVGSSNMVSRKEEDTAQAEEEEPFQDGTYDCSVS 1390 1400 1410 1420 >>NP_065880 (OMIM: 610354) RAB6A-GEF complex partner pro (1423 aa) initn: 5288 init1: 5288 opt: 5288 Z-score: 5782.8 bits: 1081.7 E(85289): 0 Smith-Waterman score: 5288; 100.0% identity (100.0% similar) in 791 aa overlap (1-791:633-1423) 10 20 30 pF1KA1 MSRYIPHPFLVVSVTLTSVSTENGITLKMP :::::::::::::::::::::::::::::: NP_065 ADCSICLYSIERKSDGPNTTAGIQVLQEVSMSRYIPHPFLVVSVTLTSVSTENGITLKMP 610 620 630 640 650 660 40 50 60 70 80 90 pF1KA1 QQARGAESIMLNLAGQLIMMQRDRSGPQIREKDSNPNNQRKLLPFCPPVVLAQSVENVWT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 QQARGAESIMLNLAGQLIMMQRDRSGPQIREKDSNPNNQRKLLPFCPPVVLAQSVENVWT 670 680 690 700 710 720 100 110 120 130 140 150 pF1KA1 TCRANKQKRHLLEALWLSCGGAGMKVWLPLFPRDHRKPHSFLSQRIMLPFHINIYPLAVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 TCRANKQKRHLLEALWLSCGGAGMKVWLPLFPRDHRKPHSFLSQRIMLPFHINIYPLAVL 730 740 750 760 770 780 160 170 180 190 200 210 pF1KA1 FEDALVLGAVNDTLLYDSLYTRNNAREQLEVLFPFCVVERTSQIYLHHILRQLLVRNLGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 FEDALVLGAVNDTLLYDSLYTRNNAREQLEVLFPFCVVERTSQIYLHHILRQLLVRNLGE 790 800 810 820 830 840 220 230 240 250 260 270 pF1KA1 QALLLAQSCATLPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 QALLLAQSCATLPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVV 850 860 870 880 890 900 280 290 300 310 320 330 pF1KA1 HCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 HCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLL 910 920 930 940 950 960 340 350 360 370 380 390 pF1KA1 FNTALEQGKWDLCRHMIRFLKAIGSGESETPPSTPTAQEPSSSGGFEFFRNRSISLSQSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 FNTALEQGKWDLCRHMIRFLKAIGSGESETPPSTPTAQEPSSSGGFEFFRNRSISLSQSA 970 980 990 1000 1010 1020 400 410 420 430 440 450 pF1KA1 ENVPASKFSLQKTLSMPSGPSGKRWSKDSDCAENMYIDMMLWRHARRLLEDVRLKDLGCF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 ENVPASKFSLQKTLSMPSGPSGKRWSKDSDCAENMYIDMMLWRHARRLLEDVRLKDLGCF 1030 1040 1050 1060 1070 1080 460 470 480 490 500 510 pF1KA1 AAQLGFELISWLCKERTRAARVDNFVIALKRLHKDFLWPLPIIPASSISSPFKNGKYRTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 AAQLGFELISWLCKERTRAARVDNFVIALKRLHKDFLWPLPIIPASSISSPFKNGKYRTV 1090 1100 1110 1120 1130 1140 520 530 540 550 560 570 pF1KA1 GEQLLKSQSADPFLNLEMDAGISNIQRSQSWLSNIGPTHHEIDTASSHGPQMQDAFLSPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 GEQLLKSQSADPFLNLEMDAGISNIQRSQSWLSNIGPTHHEIDTASSHGPQMQDAFLSPL 1150 1160 1170 1180 1190 1200 580 590 600 610 620 630 pF1KA1 SNKGDECSIGSATDLTESSSMVDGDWTMVDENFSTLSLTQSELEHISMELASKGPHKSQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 SNKGDECSIGSATDLTESSSMVDGDWTMVDENFSTLSLTQSELEHISMELASKGPHKSQV 1210 1220 1230 1240 1250 1260 640 650 660 670 680 690 pF1KA1 QLRYLLHIFMEAGCLDWCIVIGLILRESSIINQILVITQSSEVDGEMLQNIKTGLHAVDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 QLRYLLHIFMEAGCLDWCIVIGLILRESSIINQILVITQSSEVDGEMLQNIKTGLHAVDR 1270 1280 1290 1300 1310 1320 700 710 720 730 740 750 pF1KA1 WASTDCPGYKPFLNIIKPQLQKLSEITEEQVQPDAFQPITMGKTPEQTSPRAEESRGSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 WASTDCPGYKPFLNIIKPQLQKLSEITEEQVQPDAFQPITMGKTPEQTSPRAEESRGSSS 1330 1340 1350 1360 1370 1380 760 770 780 790 pF1KA1 HGSIPQGEVGSSNMVSRKEEDTAQAEEEEPFQDGTYDCSVS ::::::::::::::::::::::::::::::::::::::::: NP_065 HGSIPQGEVGSSNMVSRKEEDTAQAEEEEPFQDGTYDCSVS 1390 1400 1410 1420 >>NP_001129392 (OMIM: 610354) RAB6A-GEF complex partner (1165 aa) initn: 3422 init1: 3422 opt: 3422 Z-score: 3741.1 bits: 703.6 E(85289): 1.2e-201 Smith-Waterman score: 3422; 100.0% identity (100.0% similar) in 509 aa overlap (1-509:633-1141) 10 20 30 pF1KA1 MSRYIPHPFLVVSVTLTSVSTENGITLKMP :::::::::::::::::::::::::::::: NP_001 ADCSICLYSIERKSDGPNTTAGIQVLQEVSMSRYIPHPFLVVSVTLTSVSTENGITLKMP 610 620 630 640 650 660 40 50 60 70 80 90 pF1KA1 QQARGAESIMLNLAGQLIMMQRDRSGPQIREKDSNPNNQRKLLPFCPPVVLAQSVENVWT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QQARGAESIMLNLAGQLIMMQRDRSGPQIREKDSNPNNQRKLLPFCPPVVLAQSVENVWT 670 680 690 700 710 720 100 110 120 130 140 150 pF1KA1 TCRANKQKRHLLEALWLSCGGAGMKVWLPLFPRDHRKPHSFLSQRIMLPFHINIYPLAVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TCRANKQKRHLLEALWLSCGGAGMKVWLPLFPRDHRKPHSFLSQRIMLPFHINIYPLAVL 730 740 750 760 770 780 160 170 180 190 200 210 pF1KA1 FEDALVLGAVNDTLLYDSLYTRNNAREQLEVLFPFCVVERTSQIYLHHILRQLLVRNLGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FEDALVLGAVNDTLLYDSLYTRNNAREQLEVLFPFCVVERTSQIYLHHILRQLLVRNLGE 790 800 810 820 830 840 220 230 240 250 260 270 pF1KA1 QALLLAQSCATLPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QALLLAQSCATLPYFPHVLELMLHEVLEEEATSREPIPDPLLPTVAKFITEFPLFLQTVV 850 860 870 880 890 900 280 290 300 310 320 330 pF1KA1 HCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLL 910 920 930 940 950 960 340 350 360 370 380 390 pF1KA1 FNTALEQGKWDLCRHMIRFLKAIGSGESETPPSTPTAQEPSSSGGFEFFRNRSISLSQSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FNTALEQGKWDLCRHMIRFLKAIGSGESETPPSTPTAQEPSSSGGFEFFRNRSISLSQSA 970 980 990 1000 1010 1020 400 410 420 430 440 450 pF1KA1 ENVPASKFSLQKTLSMPSGPSGKRWSKDSDCAENMYIDMMLWRHARRLLEDVRLKDLGCF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENVPASKFSLQKTLSMPSGPSGKRWSKDSDCAENMYIDMMLWRHARRLLEDVRLKDLGCF 1030 1040 1050 1060 1070 1080 460 470 480 490 500 510 pF1KA1 AAQLGFELISWLCKERTRAARVDNFVIALKRLHKDFLWPLPIIPASSISSPFKNGKYRTV ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AAQLGFELISWLCKERTRAARVDNFVIALKRLHKDFLWPLPIIPASSISSPFKNGKYRTG 1090 1100 1110 1120 1130 1140 520 530 540 550 560 570 pF1KA1 GEQLLKSQSADPFLNLEMDAGISNIQRSQSWLSNIGPTHHEIDTASSHGPQMQDAFLSPL NP_001 NVDFMSLVQGELYFTPCIYTFCY 1150 1160 791 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 06:50:21 2016 done: Sat Nov 5 06:50:23 2016 Total Scan time: 12.660 Total Display time: 0.240 Function used was FASTA [36.3.4 Apr, 2011]