FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1435, 410 aa 1>>>pF1KA1435 410 - 410 aa - 410 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.8229+/-0.000534; mu= 10.9172+/- 0.032 mean_var=212.0762+/-46.713, 0's: 0 Z-trim(112.9): 198 B-trim: 733 in 2/51 Lambda= 0.088070 statistics sampled from 21739 (21976) to 21739 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.604), E-opt: 0.2 (0.258), width: 16 Scan time: 7.410 The best scores are: opt bits E(85289) NP_443182 (OMIM: 610418) WD repeat and FYVE domain ( 400) 1925 258.1 2.8e-68 XP_011533216 (OMIM: 610418) PREDICTED: WD repeat a ( 398) 1868 250.9 4.2e-66 XP_011533217 (OMIM: 610418) PREDICTED: WD repeat a ( 311) 1505 204.6 2.8e-52 XP_016875875 (OMIM: 610418) PREDICTED: WD repeat a ( 311) 1505 204.6 2.8e-52 NP_006089 (OMIM: 176981) receptor of activated pro ( 317) 249 45.0 0.00031 XP_016878353 (OMIM: 602703,616212) PREDICTED: kata ( 655) 228 42.8 0.003 NP_005877 (OMIM: 602703,616212) katanin p80 WD40 r ( 655) 228 42.8 0.003 XP_016878352 (OMIM: 602703,616212) PREDICTED: kata ( 655) 228 42.8 0.003 XP_006721186 (OMIM: 602703,616212) PREDICTED: kata ( 658) 228 42.8 0.003 XP_005255829 (OMIM: 602703,616212) PREDICTED: kata ( 672) 228 42.8 0.0031 XP_016878351 (OMIM: 602703,616212) PREDICTED: kata ( 672) 228 42.8 0.0031 XP_016878350 (OMIM: 602703,616212) PREDICTED: kata ( 672) 228 42.8 0.0031 XP_006721185 (OMIM: 602703,616212) PREDICTED: kata ( 675) 228 42.8 0.0031 XP_011521112 (OMIM: 602703,616212) PREDICTED: kata ( 675) 228 42.8 0.0031 XP_016878349 (OMIM: 602703,616212) PREDICTED: kata ( 675) 228 42.8 0.0031 XP_006721184 (OMIM: 602703,616212) PREDICTED: kata ( 675) 228 42.8 0.0031 NP_001186706 (OMIM: 614784,615973) POC1 centriolar ( 436) 223 41.9 0.0037 NP_758440 (OMIM: 614784,615973) POC1 centriolar pr ( 478) 223 42.0 0.0039 NP_008882 (OMIM: 601787) transcription initiation ( 800) 223 42.3 0.0053 XP_016861593 (OMIM: 614783,614813) PREDICTED: POC1 ( 321) 215 40.7 0.0062 NP_001155052 (OMIM: 614783,614813) POC1 centriolar ( 359) 215 40.8 0.0066 NP_001155053 (OMIM: 614783,614813) POC1 centriolar ( 369) 215 40.8 0.0067 NP_056241 (OMIM: 614783,614813) POC1 centriolar pr ( 407) 215 40.9 0.0071 XP_016880786 (OMIM: 604375) PREDICTED: hepatocyte ( 768) 218 41.6 0.008 XP_011523765 (OMIM: 604375) PREDICTED: hepatocyte ( 777) 218 41.6 0.0081 NP_004703 (OMIM: 604375) hepatocyte growth factor- ( 777) 218 41.6 0.0081 >>NP_443182 (OMIM: 610418) WD repeat and FYVE domain-con (400 aa) initn: 1925 init1: 1925 opt: 1925 Z-score: 1346.9 bits: 258.1 E(85289): 2.8e-68 Smith-Waterman score: 1925; 61.9% identity (88.2% similar) in 399 aa overlap (1-399:1-399) 10 20 30 40 50 60 pF1KA1 MAAEIHSRPQSSRPVLLSKIEGHQDAVTAALLIPKEDGVITASEDRTIRVWLKRDSGQYW :::::. .: . .:.::...:: :..:. :...:::.:::..:::::.:::::::::::: NP_443 MAAEIQPKPLTRKPILLQRMEGSQEVVNMAVIVPKEEGVISVSEDRTVRVWLKRDSGQYW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 PSIYHTMASPCSAMAYHHDSRRIFVGQDNGAVMEFHVSEDFNKMNFIKTYPAHQNRVSAI ::.::.: :::: :... ..::. .: :::.. :: .:::.:::. .:.: :::.::. : NP_443 PSVYHAMPSPCSCMSFNPETRRLSIGLDNGTISEFILSEDYNKMTPVKNYQAHQSRVTMI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 IFSLATEWVISTGHDKCVSWMCTRSGNMLGRHFFTSWASCLQYDFDTQYAFVGDYSGQIT .: : :::.:::.:: .: :..::. :: . .. :: ::.: .:...:.::.:::.: NP_443 LFVLELEWVLSTGQDKQFAWHCSESGQRLGGYRTSAVASGLQFDVETRHVFIGDHSGQVT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 LLKLEQNTCSVITTLKGHEGSVACLWWDPIQRLLFSGASDNSIIMWDIGGRKGRTLLLQG .:::::..:...::..:: :.:. : :::.::.::::.::.:.:::::::::: .. ::: NP_443 ILKLEQENCTLVTTFRGHTGGVTALCWDPVQRVLFSGSSDHSVIMWDIGGRKGTAIELQG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 HHDKVQSLCYLQLTRQLVSCSSDGGIAVWNMDVSREEAPQWLESDSCQKCEQPFFWNIKQ :.:.::.: : : ::::.::..::::.:::::: :.:.:.::.:::::::.::::::.:: NP_443 HNDRVQALSYAQHTRQLISCGGDGGIVVWNMDVERQETPEWLDSDSCQKCDQPFFWNFKQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 MWDTKTLGLRQHHCRKCGQAVCGKCSSKRSSYPVMGFEFQVRVCDSCYDSIKDEDRTSLA :::.: .:::::::::::.:::::::::::: :.:::::.:::::::...: ::.:. : NP_443 MWDSKKIGLRQHHCRKCGKAVCGKCSSKRSSIPLMGFEFEVRVCDSCHEAITDEERAPTA 310 320 330 340 350 360 370 380 390 400 410 pF1KA1 TFHEGKHNISHMSMDIARGLMVTCGTDRIVKIWDMTPVVGCSLATGFSPH :::..:::: :. .: .:: ..: :::...:.::::::: NP_443 TFHDSKHNIVHVHFDATRGWLLTSGTDKVIKLWDMTPVVS 370 380 390 400 >>XP_011533216 (OMIM: 610418) PREDICTED: WD repeat and F (398 aa) initn: 1992 init1: 1868 opt: 1868 Z-score: 1307.7 bits: 250.9 E(85289): 4.2e-66 Smith-Waterman score: 1868; 61.4% identity (88.0% similar) in 391 aa overlap (1-391:1-391) 10 20 30 40 50 60 pF1KA1 MAAEIHSRPQSSRPVLLSKIEGHQDAVTAALLIPKEDGVITASEDRTIRVWLKRDSGQYW :::::. .: . .:.::...:: :..:. :...:::.:::..:::::.:::::::::::: XP_011 MAAEIQPKPLTRKPILLQRMEGSQEVVNMAVIVPKEEGVISVSEDRTVRVWLKRDSGQYW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 PSIYHTMASPCSAMAYHHDSRRIFVGQDNGAVMEFHVSEDFNKMNFIKTYPAHQNRVSAI ::.::.: :::: :... ..::. .: :::.. :: .:::.:::. .:.: :::.::. : XP_011 PSVYHAMPSPCSCMSFNPETRRLSIGLDNGTISEFILSEDYNKMTPVKNYQAHQSRVTMI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 IFSLATEWVISTGHDKCVSWMCTRSGNMLGRHFFTSWASCLQYDFDTQYAFVGDYSGQIT .: : :::.:::.:: .: :..::. :: . .. :: ::.: .:...:.::.:::.: XP_011 LFVLELEWVLSTGQDKQFAWHCSESGQRLGGYRTSAVASGLQFDVETRHVFIGDHSGQVT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 LLKLEQNTCSVITTLKGHEGSVACLWWDPIQRLLFSGASDNSIIMWDIGGRKGRTLLLQG .:::::..:...::..:: :.:. : :::.::.::::.::.:.:::::::::: .. ::: XP_011 ILKLEQENCTLVTTFRGHTGGVTALCWDPVQRVLFSGSSDHSVIMWDIGGRKGTAIELQG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 HHDKVQSLCYLQLTRQLVSCSSDGGIAVWNMDVSREEAPQWLESDSCQKCEQPFFWNIKQ :.:.::.: : : ::::.::..::::.:::::: :.:.:.::.:::::::.::::::.:: XP_011 HNDRVQALSYAQHTRQLISCGGDGGIVVWNMDVERQETPEWLDSDSCQKCDQPFFWNFKQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 MWDTKTLGLRQHHCRKCGQAVCGKCSSKRSSYPVMGFEFQVRVCDSCYDSIKDEDRTSLA :::.: .:::::::::::.:::::::::::: :.:::::.:::::::...: ::.:. : XP_011 MWDSKKIGLRQHHCRKCGKAVCGKCSSKRSSIPLMGFEFEVRVCDSCHEAITDEERAPTA 310 320 330 340 350 360 370 380 390 400 410 pF1KA1 TFHEGKHNISHMSMDIARGLMVTCGTDRIVKIWDMTPVVGCSLATGFSPH :::..:::: :. .: .:: ..: :::...: XP_011 TFHDSKHNIVHVHFDATRGWLLTSGTDKVIKPTEPLRG 370 380 390 >>XP_011533217 (OMIM: 610418) PREDICTED: WD repeat and F (311 aa) initn: 1505 init1: 1505 opt: 1505 Z-score: 1059.6 bits: 204.6 E(85289): 2.8e-52 Smith-Waterman score: 1505; 63.2% identity (88.3% similar) in 307 aa overlap (93-399:4-310) 70 80 90 100 110 120 pF1KA1 IYHTMASPCSAMAYHHDSRRIFVGQDNGAVMEFHVSEDFNKMNFIKTYPAHQNRVSAIIF .:: .:::.:::. .:.: :::.::. :.: XP_011 MQCLEFILSEDYNKMTPVKNYQAHQSRVTMILF 10 20 30 130 140 150 160 170 180 pF1KA1 SLATEWVISTGHDKCVSWMCTRSGNMLGRHFFTSWASCLQYDFDTQYAFVGDYSGQITLL : :::.:::.:: .: :..::. :: . .. :: ::.: .:...:.::.:::.:.: XP_011 VLELEWVLSTGQDKQFAWHCSESGQRLGGYRTSAVASGLQFDVETRHVFIGDHSGQVTIL 40 50 60 70 80 90 190 200 210 220 230 240 pF1KA1 KLEQNTCSVITTLKGHEGSVACLWWDPIQRLLFSGASDNSIIMWDIGGRKGRTLLLQGHH ::::..:...::..:: :.:. : :::.::.::::.::.:.:::::::::: .. ::::. XP_011 KLEQENCTLVTTFRGHTGGVTALCWDPVQRVLFSGSSDHSVIMWDIGGRKGTAIELQGHN 100 110 120 130 140 150 250 260 270 280 290 300 pF1KA1 DKVQSLCYLQLTRQLVSCSSDGGIAVWNMDVSREEAPQWLESDSCQKCEQPFFWNIKQMW :.::.: : : ::::.::..::::.:::::: :.:.:.::.:::::::.::::::.:::: XP_011 DRVQALSYAQHTRQLISCGGDGGIVVWNMDVERQETPEWLDSDSCQKCDQPFFWNFKQMW 160 170 180 190 200 210 310 320 330 340 350 360 pF1KA1 DTKTLGLRQHHCRKCGQAVCGKCSSKRSSYPVMGFEFQVRVCDSCYDSIKDEDRTSLATF :.: .:::::::::::.:::::::::::: :.:::::.:::::::...: ::.:. ::: XP_011 DSKKIGLRQHHCRKCGKAVCGKCSSKRSSIPLMGFEFEVRVCDSCHEAITDEERAPTATF 220 230 240 250 260 270 370 380 390 400 410 pF1KA1 HEGKHNISHMSMDIARGLMVTCGTDRIVKIWDMTPVVGCSLATGFSPH :..:::: :. .: .:: ..: :::...:.::::::: XP_011 HDSKHNIVHVHFDATRGWLLTSGTDKVIKLWDMTPVVS 280 290 300 310 >>XP_016875875 (OMIM: 610418) PREDICTED: WD repeat and F (311 aa) initn: 1505 init1: 1505 opt: 1505 Z-score: 1059.6 bits: 204.6 E(85289): 2.8e-52 Smith-Waterman score: 1505; 63.2% identity (88.3% similar) in 307 aa overlap (93-399:4-310) 70 80 90 100 110 120 pF1KA1 IYHTMASPCSAMAYHHDSRRIFVGQDNGAVMEFHVSEDFNKMNFIKTYPAHQNRVSAIIF .:: .:::.:::. .:.: :::.::. :.: XP_016 MQCLEFILSEDYNKMTPVKNYQAHQSRVTMILF 10 20 30 130 140 150 160 170 180 pF1KA1 SLATEWVISTGHDKCVSWMCTRSGNMLGRHFFTSWASCLQYDFDTQYAFVGDYSGQITLL : :::.:::.:: .: :..::. :: . .. :: ::.: .:...:.::.:::.:.: XP_016 VLELEWVLSTGQDKQFAWHCSESGQRLGGYRTSAVASGLQFDVETRHVFIGDHSGQVTIL 40 50 60 70 80 90 190 200 210 220 230 240 pF1KA1 KLEQNTCSVITTLKGHEGSVACLWWDPIQRLLFSGASDNSIIMWDIGGRKGRTLLLQGHH ::::..:...::..:: :.:. : :::.::.::::.::.:.:::::::::: .. ::::. XP_016 KLEQENCTLVTTFRGHTGGVTALCWDPVQRVLFSGSSDHSVIMWDIGGRKGTAIELQGHN 100 110 120 130 140 150 250 260 270 280 290 300 pF1KA1 DKVQSLCYLQLTRQLVSCSSDGGIAVWNMDVSREEAPQWLESDSCQKCEQPFFWNIKQMW :.::.: : : ::::.::..::::.:::::: :.:.:.::.:::::::.::::::.:::: XP_016 DRVQALSYAQHTRQLISCGGDGGIVVWNMDVERQETPEWLDSDSCQKCDQPFFWNFKQMW 160 170 180 190 200 210 310 320 330 340 350 360 pF1KA1 DTKTLGLRQHHCRKCGQAVCGKCSSKRSSYPVMGFEFQVRVCDSCYDSIKDEDRTSLATF :.: .:::::::::::.:::::::::::: :.:::::.:::::::...: ::.:. ::: XP_016 DSKKIGLRQHHCRKCGKAVCGKCSSKRSSIPLMGFEFEVRVCDSCHEAITDEERAPTATF 220 230 240 250 260 270 370 380 390 400 410 pF1KA1 HEGKHNISHMSMDIARGLMVTCGTDRIVKIWDMTPVVGCSLATGFSPH :..:::: :. .: .:: ..: :::...:.::::::: XP_016 HDSKHNIVHVHFDATRGWLLTSGTDKVIKLWDMTPVVS 280 290 300 310 >>NP_006089 (OMIM: 176981) receptor of activated protein (317 aa) initn: 206 init1: 81 opt: 249 Z-score: 197.1 bits: 45.0 E(85289): 0.00031 Smith-Waterman score: 249; 23.0% identity (54.1% similar) in 305 aa overlap (16-307:7-298) 10 20 30 40 50 pF1KA1 MAAEIHSRPQSSRPVLLSKIEGHQDAVTAALLIPK-EDGVITASEDRTIRVW-LKRDSGQ : . ..::. :: :. : ...::.:.:: .: : :: . NP_006 MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETN 10 20 30 40 50 60 70 80 90 100 110 pF1KA1 YW-PS-IYHTMASPCSAMAYHHDSRRIFVGQDNGAVMEFHVSEDFNKMNFIKTYPAHQNR : :. . . : .. :.. . :. .:.. . .. . :. .: . NP_006 YGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFV----GHTKD 60 70 80 90 100 120 130 140 150 160 170 pF1KA1 VSAIIFSLATEWVISTGHDKCVS-W----MCTRSGNMLGRHFFTSWASCLQYDFDTQYAF : .. :: .. ..: ..:: .. : .: . . . . :.::.... ... . NP_006 VLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYT---VQDESHSEWVSCVRFSPNSSNPI 110 120 130 140 150 160 180 190 200 210 220 230 pF1KA1 VGDYSGQITLLKL-EQNTCSVITTLKGHEGSVACLWWDPIQRLLFSGASDNSIIMWDIGG . . : :.:. . .:.. :. :: : . . .: : ::..:.. ..::.. NP_006 IVS-CGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLN- 170 180 190 200 210 220 240 250 260 270 280 pF1KA1 RKGRTLLLQGHHDKVQSLCYLQLTRQLVSCSSDG-GIAVWNMD--VSREEAPQWLESDSC .:. : : ...::. : :.. : .: .:... . .: : . : : NP_006 -EGKHLYTLDGGDIINALCFSPNRYWL--CAATGPSIKIWDLEGKIIVDELKQEVISTS- 230 240 250 260 270 290 300 310 320 330 340 pF1KA1 QKCEQPFFWNIKQMWDTKTLGLRQHHCRKCGQAVCGKCSSKRSSYPVMGFEFQVRVCDSC .: : : .. : .:: NP_006 SKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVTIGTR 280 290 300 310 >>XP_016878353 (OMIM: 602703,616212) PREDICTED: katanin (655 aa) initn: 205 init1: 115 opt: 228 Z-score: 179.3 bits: 42.8 E(85289): 0.003 Smith-Waterman score: 228; 25.9% identity (62.0% similar) in 166 aa overlap (112-275:18-180) 90 100 110 120 130 pF1KA1 RIFVGQDNGAVMEFHVSEDFNKMNFIKTYPAHQNRVSAIIFSLATEWVISTGHDKC-VS- :: . ::..... :. ...:: : : :. XP_016 MATPVVTKTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNL 10 20 30 40 140 150 160 170 180 190 pF1KA1 WMCTRSGNMLGRHFFTSWASCLQYDFDTQYAFVGDYSGQITLLKLEQNTCSVITTLKGHE : .. . ... :: . .. . . .:. ::.: . :: . ... :: ::. XP_016 WSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLE--AAKILRTLMGHK 50 60 70 80 90 100 200 210 220 230 240 250 pF1KA1 GSVACLWWDPIQRLLFSGASDNSIIMWDIGGRKGRTLLLQGHHDKVQSLCYLQLTRQLVS ... : . : ... ::..:..: .::: ::: .. .:: . :. : . . :.: XP_016 ANICSLDFHPYGEFVASGSQDTNIKLWDIR-RKGCVFRYRGHSQAVRCLRFSPDGKWLAS 110 120 130 140 150 160 260 270 280 290 300 310 pF1KA1 CSSDGGIAVWNMDVSREEAPQWLESDSCQKCEQPFFWNIKQMWDTKTLGLRQHHCRKCGQ ..: . .:.. ... XP_016 AADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVV 170 180 190 200 210 220 >>NP_005877 (OMIM: 602703,616212) katanin p80 WD40 repea (655 aa) initn: 205 init1: 115 opt: 228 Z-score: 179.3 bits: 42.8 E(85289): 0.003 Smith-Waterman score: 228; 25.9% identity (62.0% similar) in 166 aa overlap (112-275:18-180) 90 100 110 120 130 pF1KA1 RIFVGQDNGAVMEFHVSEDFNKMNFIKTYPAHQNRVSAIIFSLATEWVISTGHDKC-VS- :: . ::..... :. ...:: : : :. NP_005 MATPVVTKTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNL 10 20 30 40 140 150 160 170 180 190 pF1KA1 WMCTRSGNMLGRHFFTSWASCLQYDFDTQYAFVGDYSGQITLLKLEQNTCSVITTLKGHE : .. . ... :: . .. . . .:. ::.: . :: . ... :: ::. NP_005 WSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLE--AAKILRTLMGHK 50 60 70 80 90 100 200 210 220 230 240 250 pF1KA1 GSVACLWWDPIQRLLFSGASDNSIIMWDIGGRKGRTLLLQGHHDKVQSLCYLQLTRQLVS ... : . : ... ::..:..: .::: ::: .. .:: . :. : . . :.: NP_005 ANICSLDFHPYGEFVASGSQDTNIKLWDIR-RKGCVFRYRGHSQAVRCLRFSPDGKWLAS 110 120 130 140 150 160 260 270 280 290 300 310 pF1KA1 CSSDGGIAVWNMDVSREEAPQWLESDSCQKCEQPFFWNIKQMWDTKTLGLRQHHCRKCGQ ..: . .:.. ... NP_005 AADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVV 170 180 190 200 210 220 >>XP_016878352 (OMIM: 602703,616212) PREDICTED: katanin (655 aa) initn: 205 init1: 115 opt: 228 Z-score: 179.3 bits: 42.8 E(85289): 0.003 Smith-Waterman score: 228; 25.9% identity (62.0% similar) in 166 aa overlap (112-275:18-180) 90 100 110 120 130 pF1KA1 RIFVGQDNGAVMEFHVSEDFNKMNFIKTYPAHQNRVSAIIFSLATEWVISTGHDKC-VS- :: . ::..... :. ...:: : : :. XP_016 MATPVVTKTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNL 10 20 30 40 140 150 160 170 180 190 pF1KA1 WMCTRSGNMLGRHFFTSWASCLQYDFDTQYAFVGDYSGQITLLKLEQNTCSVITTLKGHE : .. . ... :: . .. . . .:. ::.: . :: . ... :: ::. XP_016 WSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLE--AAKILRTLMGHK 50 60 70 80 90 100 200 210 220 230 240 250 pF1KA1 GSVACLWWDPIQRLLFSGASDNSIIMWDIGGRKGRTLLLQGHHDKVQSLCYLQLTRQLVS ... : . : ... ::..:..: .::: ::: .. .:: . :. : . . :.: XP_016 ANICSLDFHPYGEFVASGSQDTNIKLWDIR-RKGCVFRYRGHSQAVRCLRFSPDGKWLAS 110 120 130 140 150 160 260 270 280 290 300 310 pF1KA1 CSSDGGIAVWNMDVSREEAPQWLESDSCQKCEQPFFWNIKQMWDTKTLGLRQHHCRKCGQ ..: . .:.. ... XP_016 AADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVV 170 180 190 200 210 220 >>XP_006721186 (OMIM: 602703,616212) PREDICTED: katanin (658 aa) initn: 205 init1: 115 opt: 228 Z-score: 179.2 bits: 42.8 E(85289): 0.003 Smith-Waterman score: 228; 25.9% identity (62.0% similar) in 166 aa overlap (112-275:18-180) 90 100 110 120 130 pF1KA1 RIFVGQDNGAVMEFHVSEDFNKMNFIKTYPAHQNRVSAIIFSLATEWVISTGHDKC-VS- :: . ::..... :. ...:: : : :. XP_006 MATPVVTKTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNL 10 20 30 40 140 150 160 170 180 190 pF1KA1 WMCTRSGNMLGRHFFTSWASCLQYDFDTQYAFVGDYSGQITLLKLEQNTCSVITTLKGHE : .. . ... :: . .. . . .:. ::.: . :: . ... :: ::. XP_006 WSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLE--AAKILRTLMGHK 50 60 70 80 90 100 200 210 220 230 240 250 pF1KA1 GSVACLWWDPIQRLLFSGASDNSIIMWDIGGRKGRTLLLQGHHDKVQSLCYLQLTRQLVS ... : . : ... ::..:..: .::: ::: .. .:: . :. : . . :.: XP_006 ANICSLDFHPYGEFVASGSQDTNIKLWDIR-RKGCVFRYRGHSQAVRCLRFSPDGKWLAS 110 120 130 140 150 160 260 270 280 290 300 310 pF1KA1 CSSDGGIAVWNMDVSREEAPQWLESDSCQKCEQPFFWNIKQMWDTKTLGLRQHHCRKCGQ ..: . .:.. ... XP_006 AADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVV 170 180 190 200 210 220 >>XP_005255829 (OMIM: 602703,616212) PREDICTED: katanin (672 aa) initn: 205 init1: 115 opt: 228 Z-score: 179.1 bits: 42.8 E(85289): 0.0031 Smith-Waterman score: 228; 25.9% identity (62.0% similar) in 166 aa overlap (112-275:18-180) 90 100 110 120 130 pF1KA1 RIFVGQDNGAVMEFHVSEDFNKMNFIKTYPAHQNRVSAIIFSLATEWVISTGHDKC-VS- :: . ::..... :. ...:: : : :. XP_005 MATPVVTKTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNL 10 20 30 40 140 150 160 170 180 190 pF1KA1 WMCTRSGNMLGRHFFTSWASCLQYDFDTQYAFVGDYSGQITLLKLEQNTCSVITTLKGHE : .. . ... :: . .. . . .:. ::.: . :: . ... :: ::. XP_005 WSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLE--AAKILRTLMGHK 50 60 70 80 90 100 200 210 220 230 240 250 pF1KA1 GSVACLWWDPIQRLLFSGASDNSIIMWDIGGRKGRTLLLQGHHDKVQSLCYLQLTRQLVS ... : . : ... ::..:..: .::: ::: .. .:: . :. : . . :.: XP_005 ANICSLDFHPYGEFVASGSQDTNIKLWDIR-RKGCVFRYRGHSQAVRCLRFSPDGKWLAS 110 120 130 140 150 160 260 270 280 290 300 310 pF1KA1 CSSDGGIAVWNMDVSREEAPQWLESDSCQKCEQPFFWNIKQMWDTKTLGLRQHHCRKCGQ ..: . .:.. ... XP_005 AADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVV 170 180 190 200 210 220 410 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 06:15:27 2016 done: Thu Nov 3 06:15:28 2016 Total Scan time: 7.410 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]