Result of FASTA (omim) for
pF1KA1454
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA1454, 1399 aa
1>>>pF1KA1454 1399 - 1399 aa - 1399 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 12.9338+/-0.000743; mu= -11.6330+/- 0.046
mean_var=714.2435+/-144.863, 0's: 0 Z-trim(115.9): 53 B-trim: 0 in 0/53
Lambda= 0.047990
statistics sampled from 26643 (26680) to 26643 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.625), E-opt: 0.2 (0.313), width: 16
Scan time: 16.180
The best scores are: opt bits E(85289)
NP_065894 (OMIM: 611611) S phase cyclin A-associat (1400) 9144 650.8 2e-185
XP_016877758 (OMIM: 611611) PREDICTED: S phase cyc (1400) 9144 650.8 2e-185
XP_016877759 (OMIM: 611611) PREDICTED: S phase cyc (1400) 9144 650.8 2e-185
XP_005254476 (OMIM: 611611) PREDICTED: S phase cyc (1400) 9144 650.8 2e-185
XP_016877757 (OMIM: 611611) PREDICTED: S phase cyc (1406) 9122 649.3 5.9e-185
XP_005254474 (OMIM: 611611) PREDICTED: S phase cyc (1406) 9122 649.3 5.9e-185
XP_011519952 (OMIM: 611611) PREDICTED: S phase cyc (1406) 9122 649.3 5.9e-185
XP_016877756 (OMIM: 611611) PREDICTED: S phase cyc (1425) 8896 633.7 3e-180
XP_011519954 (OMIM: 611611) PREDICTED: S phase cyc (1390) 8874 632.1 8.6e-180
XP_016877755 (OMIM: 611611) PREDICTED: S phase cyc (1431) 8874 632.1 8.7e-180
XP_016877762 (OMIM: 611611) PREDICTED: S phase cyc (1266) 8255 589.2 6.5e-167
XP_011519955 (OMIM: 611611) PREDICTED: S phase cyc (1272) 8233 587.7 1.9e-166
NP_001139395 (OMIM: 611611) S phase cyclin A-assoc (1154) 7435 532.4 7.5e-150
XP_011519956 (OMIM: 611611) PREDICTED: S phase cyc (1160) 7413 530.9 2.2e-149
XP_016877766 (OMIM: 611611) PREDICTED: S phase cyc (1119) 7275 521.3 1.6e-146
XP_016877767 (OMIM: 611611) PREDICTED: S phase cyc (1119) 7275 521.3 1.6e-146
XP_016877765 (OMIM: 611611) PREDICTED: S phase cyc (1125) 7253 519.8 4.6e-146
XP_016877764 (OMIM: 611611) PREDICTED: S phase cyc (1125) 7253 519.8 4.6e-146
XP_016877763 (OMIM: 611611) PREDICTED: S phase cyc (1190) 7233 518.4 1.2e-145
XP_016877761 (OMIM: 611611) PREDICTED: S phase cyc (1354) 7118 510.5 3.3e-143
XP_016877760 (OMIM: 611611) PREDICTED: S phase cyc (1379) 6870 493.4 5e-138
XP_016877769 (OMIM: 611611) PREDICTED: S phase cyc (1066) 6361 458.0 1.7e-127
XP_016877768 (OMIM: 611611) PREDICTED: S phase cyc (1066) 6360 457.9 1.8e-127
XP_016877770 (OMIM: 611611) PREDICTED: S phase cyc (1065) 6359 457.8 1.9e-127
XP_016877772 (OMIM: 611611) PREDICTED: S phase cyc ( 861) 5434 393.7 3.2e-108
XP_016877771 (OMIM: 611611) PREDICTED: S phase cyc ( 892) 5164 375.0 1.4e-102
XP_011519958 (OMIM: 611611) PREDICTED: S phase cyc ( 786) 5066 368.2 1.4e-100
XP_016877773 (OMIM: 611611) PREDICTED: S phase cyc ( 700) 3824 282.1 1e-74
>>NP_065894 (OMIM: 611611) S phase cyclin A-associated p (1400 aa)
initn: 9144 init1: 9144 opt: 9144 Z-score: 3449.8 bits: 650.8 E(85289): 2e-185
Smith-Waterman score: 9144; 99.9% identity (99.9% similar) in 1399 aa overlap (1-1399:2-1400)
10 20 30 40 50
pF1KA1 MASFQRSNSHDKVRRIVAEEGRTARNLIAWSVPLESKDDDGKPKCQTGGKSKRTIQGTH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MMASFQRSNSHDKVRRIVAEEGRTARNLIAWSVPLESKDDDGKPKCQTGGKSKRTIQGTH
10 20 30 40 50 60
60 70 80 90 100 110
pF1KA1 KTTKQSTAVDCKITSSTTGDKHFDKSPTKTRHPRKIDLRARYWAFLFDNLRRAVDEIYVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 KTTKQSTAVDCKITSSTTGDKHFDKSPTKTRHPRKIDLRARYWAFLFDNLRRAVDEIYVT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KA1 CESDQSVVECKEVLMMLDNYVRDFKALIDWIQLQEKLEKTDAQSRPTSLAWEVKKMSPGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 CESDQSVVECKEVLMMLDNYVRDFKALIDWIQLQEKLEKTDAQSRPTSLAWEVKKMSPGR
130 140 150 160 170 180
180 190 200 210 220 230
pF1KA1 HVIPSPSTDRINVTSNARRSLNFGGSTGTVPAPRLAPTGVSWADKVKAHHTGSTASSEIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 HVIPSPSTDRINVTSNARRSLNFGGSTGTVPAPRLAPTGVSWADKVKAHHTGSTASSEIT
190 200 210 220 230 240
240 250 260 270 280 290
pF1KA1 PAQSCPPMTVQKASRKNERKDAEGWETVQRGRPIRSRSTAVMPKVSLATEATRSKDDSDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 PAQSCPPMTVQKASRKNERKDAEGWETVQRGRPIRSRSTAVMPKVSLATEATRSKDDSDK
250 260 270 280 290 300
300 310 320 330 340 350
pF1KA1 ENVCLLPDESIQKGQFVGDGTSNTIESHPKDSLHSCDHPLAEKTQFTVSTLDDVKNSGSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 ENVCLLPDESIQKGQFVGDGTSNTIESHPKDSLHSCDHPLAEKTQFTVSTLDDVKNSGSI
310 320 330 340 350 360
360 370 380 390 400 410
pF1KA1 RDNYVRTSEISAVHIDTECVSVMLQAGTPPLQVNEEKFPAEKARIENEMDPSDISNSMAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 RDNYVRTSEISAVHIDTECVSVMLQAGTPPLQVNEEKFPAEKARIENEMDPSDISNSMAE
370 380 390 400 410 420
420 430 440 450 460 470
pF1KA1 VLAKKEELADRLEKANEEAIASAIAEEEQLTREIEAEENNDINIETDNDSDFSASMGSGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 VLAKKEELADRLEKANEEAIASAIAEEEQLTREIEAEENNDINIETDNDSDFSASMGSGS
430 440 450 460 470 480
480 490 500 510 520 530
pF1KA1 VSFCGMSMDWNDVLADYEARESWRQNTSWGDIVEEEPARPPGHGIHMHEKLSSPSRKRTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 VSFCGMSMDWNDVLADYEARESWRQNTSWGDIVEEEPARPPGHGIHMHEKLSSPSRKRTI
490 500 510 520 530 540
540 550 560 570 580 590
pF1KA1 AESKKKHEEKQMKAQQLREKLREEKTLKLQKLLEREKDVRKWKEELLDQRRRMMEEKLLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 AESKKKHEEKQMKAQQLREKLREEKTLKLQKLLEREKDVRKWKEELLDQRRRMMEEKLLH
550 560 570 580 590 600
600 610 620 630 640 650
pF1KA1 AEFKREVQLQAIVKKAQEEEAKVNEIAFINTLEAQNKRHDVLSKLKEYEQRLNELQEERQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 AEFKREVQLQAIVKKAQEEEAKVNEIAFINTLEAQNKRHDVLSKLKEYEQRLNELQEERQ
610 620 630 640 650 660
660 670 680 690 700 710
pF1KA1 RRQEEKQARDEAVQERKRALEAERQARVEELLMKRKEQEARIEQQRQEKEKAREDAARER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 RRQEEKQARDEAVQERKRALEAERQARVEELLMKRKEQEARIEQQRQEKEKAREDAARER
670 680 690 700 710 720
720 730 740 750 760 770
pF1KA1 ARDREERLAALTAAQQEAMEELQKKIQLKHDESIRRHMEQIEQRKEKAAELSSGRHANTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 ARDREERLAALTAAQQEAMEELQKKIQLKHDESIRRHMEQIEQRKEKAAELSSGRHANTD
730 740 750 760 770 780
780 790 800 810 820 830
pF1KA1 YAPKLTPYERKKQCSLCNVLISSEVYLFSHVKGRKHQQAVRENTSIQGRELSDEEVEHLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 YAPKLTPYERKKQCSLCNVLISSEVYLFSHVKGRKHQQAVRENTSIQGRELSDEEVEHLS
790 800 810 820 830 840
840 850 860 870 880 890
pF1KA1 LKKYIIDIVVESTAPAEALKDGEERQKNKKKAKKIKARMNFRAKEYESLMETKNSGSDSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LKKYIIDIVVESTAPAEALKDGEERQKNKKKAKKIKARMNFRAKEYESLMETKNSGSDSP
850 860 870 880 890 900
900 910 920 930 940 950
pF1KA1 YKAKLQRLAKDLLKQVQVQDSGSWANNKVSALDRTLGEITRILEKENVADQIAFQAAGGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 YKAKLQRLAKDLLKQVQVQDSGSWANNKVSALDRTLGEITRILEKENVADQIAFQAAGGL
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KA1 TALEHILQAVVPATNVNTVLRIPPKSLCNAINVYNLTCNNCSENCSDVLFSNKITFLMDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 TALEHILQAVVPATNVNTVLRIPPKSLCNAINVYNLTCNNCSENCSDVLFSNKITFLMDL
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KA1 LIHQLTVYVPDENNTILGRNTNKQVFEGLTTGLLKVSAVVLGCLIANRPDGNCQPATPKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LIHQLTVYVPDENNTILGRNTNKQVFEGLTTGLLKVSAVVLGCLIANRPDGNCQPATPKI
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KA1 PTQEMKNKTSQGDPFNNRVQDLISYVVNMGLIDKLCACFLSVQGPVDENPKMAIFLQHAA
:::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 PTQEMKNKPSQGDPFNNRVQDLISYVVNMGLIDKLCACFLSVQGPVDENPKMAIFLQHAA
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170 1180 1190
pF1KA1 GLLHAMCTLCFAVTGRSYSIFDNNRQDPTGLTAALQATDLAGVLHMLYCVLFHGTILDPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 GLLHAMCTLCFAVTGRSYSIFDNNRQDPTGLTAALQATDLAGVLHMLYCVLFHGTILDPS
1150 1160 1170 1180 1190 1200
1200 1210 1220 1230 1240 1250
pF1KA1 TASPKENYTQNTIQVAIQSLRFFNSFAALHLPAFQSIVGAEGLSLAFRHMASSLLGHCSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 TASPKENYTQNTIQVAIQSLRFFNSFAALHLPAFQSIVGAEGLSLAFRHMASSLLGHCSQ
1210 1220 1230 1240 1250 1260
1260 1270 1280 1290 1300 1310
pF1KA1 VSCESLLHEVIVCVGYFTVNHPDNQVIVQSGRHPTVLQKLCQLPFQYFSDPRLIKVLFPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 VSCESLLHEVIVCVGYFTVNHPDNQVIVQSGRHPTVLQKLCQLPFQYFSDPRLIKVLFPS
1270 1280 1290 1300 1310 1320
1320 1330 1340 1350 1360 1370
pF1KA1 LIAACYNNHQNKIILEQEMSCVLLATFIQDLAQTPGQAENQPYQPKGKCLGSQDYLELAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LIAACYNNHQNKIILEQEMSCVLLATFIQDLAQTPGQAENQPYQPKGKCLGSQDYLELAN
1330 1340 1350 1360 1370 1380
1380 1390
pF1KA1 RFPQQAWEEARQFFLKKEKK
::::::::::::::::::::
NP_065 RFPQQAWEEARQFFLKKEKK
1390 1400
>>XP_016877758 (OMIM: 611611) PREDICTED: S phase cyclin (1400 aa)
initn: 9144 init1: 9144 opt: 9144 Z-score: 3449.8 bits: 650.8 E(85289): 2e-185
Smith-Waterman score: 9144; 99.9% identity (99.9% similar) in 1399 aa overlap (1-1399:2-1400)
10 20 30 40 50
pF1KA1 MASFQRSNSHDKVRRIVAEEGRTARNLIAWSVPLESKDDDGKPKCQTGGKSKRTIQGTH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MMASFQRSNSHDKVRRIVAEEGRTARNLIAWSVPLESKDDDGKPKCQTGGKSKRTIQGTH
10 20 30 40 50 60
60 70 80 90 100 110
pF1KA1 KTTKQSTAVDCKITSSTTGDKHFDKSPTKTRHPRKIDLRARYWAFLFDNLRRAVDEIYVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTTKQSTAVDCKITSSTTGDKHFDKSPTKTRHPRKIDLRARYWAFLFDNLRRAVDEIYVT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KA1 CESDQSVVECKEVLMMLDNYVRDFKALIDWIQLQEKLEKTDAQSRPTSLAWEVKKMSPGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CESDQSVVECKEVLMMLDNYVRDFKALIDWIQLQEKLEKTDAQSRPTSLAWEVKKMSPGR
130 140 150 160 170 180
180 190 200 210 220 230
pF1KA1 HVIPSPSTDRINVTSNARRSLNFGGSTGTVPAPRLAPTGVSWADKVKAHHTGSTASSEIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HVIPSPSTDRINVTSNARRSLNFGGSTGTVPAPRLAPTGVSWADKVKAHHTGSTASSEIT
190 200 210 220 230 240
240 250 260 270 280 290
pF1KA1 PAQSCPPMTVQKASRKNERKDAEGWETVQRGRPIRSRSTAVMPKVSLATEATRSKDDSDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAQSCPPMTVQKASRKNERKDAEGWETVQRGRPIRSRSTAVMPKVSLATEATRSKDDSDK
250 260 270 280 290 300
300 310 320 330 340 350
pF1KA1 ENVCLLPDESIQKGQFVGDGTSNTIESHPKDSLHSCDHPLAEKTQFTVSTLDDVKNSGSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENVCLLPDESIQKGQFVGDGTSNTIESHPKDSLHSCDHPLAEKTQFTVSTLDDVKNSGSI
310 320 330 340 350 360
360 370 380 390 400 410
pF1KA1 RDNYVRTSEISAVHIDTECVSVMLQAGTPPLQVNEEKFPAEKARIENEMDPSDISNSMAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDNYVRTSEISAVHIDTECVSVMLQAGTPPLQVNEEKFPAEKARIENEMDPSDISNSMAE
370 380 390 400 410 420
420 430 440 450 460 470
pF1KA1 VLAKKEELADRLEKANEEAIASAIAEEEQLTREIEAEENNDINIETDNDSDFSASMGSGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLAKKEELADRLEKANEEAIASAIAEEEQLTREIEAEENNDINIETDNDSDFSASMGSGS
430 440 450 460 470 480
480 490 500 510 520 530
pF1KA1 VSFCGMSMDWNDVLADYEARESWRQNTSWGDIVEEEPARPPGHGIHMHEKLSSPSRKRTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSFCGMSMDWNDVLADYEARESWRQNTSWGDIVEEEPARPPGHGIHMHEKLSSPSRKRTI
490 500 510 520 530 540
540 550 560 570 580 590
pF1KA1 AESKKKHEEKQMKAQQLREKLREEKTLKLQKLLEREKDVRKWKEELLDQRRRMMEEKLLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AESKKKHEEKQMKAQQLREKLREEKTLKLQKLLEREKDVRKWKEELLDQRRRMMEEKLLH
550 560 570 580 590 600
600 610 620 630 640 650
pF1KA1 AEFKREVQLQAIVKKAQEEEAKVNEIAFINTLEAQNKRHDVLSKLKEYEQRLNELQEERQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AEFKREVQLQAIVKKAQEEEAKVNEIAFINTLEAQNKRHDVLSKLKEYEQRLNELQEERQ
610 620 630 640 650 660
660 670 680 690 700 710
pF1KA1 RRQEEKQARDEAVQERKRALEAERQARVEELLMKRKEQEARIEQQRQEKEKAREDAARER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRQEEKQARDEAVQERKRALEAERQARVEELLMKRKEQEARIEQQRQEKEKAREDAARER
670 680 690 700 710 720
720 730 740 750 760 770
pF1KA1 ARDREERLAALTAAQQEAMEELQKKIQLKHDESIRRHMEQIEQRKEKAAELSSGRHANTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARDREERLAALTAAQQEAMEELQKKIQLKHDESIRRHMEQIEQRKEKAAELSSGRHANTD
730 740 750 760 770 780
780 790 800 810 820 830
pF1KA1 YAPKLTPYERKKQCSLCNVLISSEVYLFSHVKGRKHQQAVRENTSIQGRELSDEEVEHLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YAPKLTPYERKKQCSLCNVLISSEVYLFSHVKGRKHQQAVRENTSIQGRELSDEEVEHLS
790 800 810 820 830 840
840 850 860 870 880 890
pF1KA1 LKKYIIDIVVESTAPAEALKDGEERQKNKKKAKKIKARMNFRAKEYESLMETKNSGSDSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKKYIIDIVVESTAPAEALKDGEERQKNKKKAKKIKARMNFRAKEYESLMETKNSGSDSP
850 860 870 880 890 900
900 910 920 930 940 950
pF1KA1 YKAKLQRLAKDLLKQVQVQDSGSWANNKVSALDRTLGEITRILEKENVADQIAFQAAGGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YKAKLQRLAKDLLKQVQVQDSGSWANNKVSALDRTLGEITRILEKENVADQIAFQAAGGL
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KA1 TALEHILQAVVPATNVNTVLRIPPKSLCNAINVYNLTCNNCSENCSDVLFSNKITFLMDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TALEHILQAVVPATNVNTVLRIPPKSLCNAINVYNLTCNNCSENCSDVLFSNKITFLMDL
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KA1 LIHQLTVYVPDENNTILGRNTNKQVFEGLTTGLLKVSAVVLGCLIANRPDGNCQPATPKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIHQLTVYVPDENNTILGRNTNKQVFEGLTTGLLKVSAVVLGCLIANRPDGNCQPATPKI
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KA1 PTQEMKNKTSQGDPFNNRVQDLISYVVNMGLIDKLCACFLSVQGPVDENPKMAIFLQHAA
:::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTQEMKNKPSQGDPFNNRVQDLISYVVNMGLIDKLCACFLSVQGPVDENPKMAIFLQHAA
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170 1180 1190
pF1KA1 GLLHAMCTLCFAVTGRSYSIFDNNRQDPTGLTAALQATDLAGVLHMLYCVLFHGTILDPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLLHAMCTLCFAVTGRSYSIFDNNRQDPTGLTAALQATDLAGVLHMLYCVLFHGTILDPS
1150 1160 1170 1180 1190 1200
1200 1210 1220 1230 1240 1250
pF1KA1 TASPKENYTQNTIQVAIQSLRFFNSFAALHLPAFQSIVGAEGLSLAFRHMASSLLGHCSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TASPKENYTQNTIQVAIQSLRFFNSFAALHLPAFQSIVGAEGLSLAFRHMASSLLGHCSQ
1210 1220 1230 1240 1250 1260
1260 1270 1280 1290 1300 1310
pF1KA1 VSCESLLHEVIVCVGYFTVNHPDNQVIVQSGRHPTVLQKLCQLPFQYFSDPRLIKVLFPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSCESLLHEVIVCVGYFTVNHPDNQVIVQSGRHPTVLQKLCQLPFQYFSDPRLIKVLFPS
1270 1280 1290 1300 1310 1320
1320 1330 1340 1350 1360 1370
pF1KA1 LIAACYNNHQNKIILEQEMSCVLLATFIQDLAQTPGQAENQPYQPKGKCLGSQDYLELAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIAACYNNHQNKIILEQEMSCVLLATFIQDLAQTPGQAENQPYQPKGKCLGSQDYLELAN
1330 1340 1350 1360 1370 1380
1380 1390
pF1KA1 RFPQQAWEEARQFFLKKEKK
::::::::::::::::::::
XP_016 RFPQQAWEEARQFFLKKEKK
1390 1400
>>XP_016877759 (OMIM: 611611) PREDICTED: S phase cyclin (1400 aa)
initn: 9144 init1: 9144 opt: 9144 Z-score: 3449.8 bits: 650.8 E(85289): 2e-185
Smith-Waterman score: 9144; 99.9% identity (99.9% similar) in 1399 aa overlap (1-1399:2-1400)
10 20 30 40 50
pF1KA1 MASFQRSNSHDKVRRIVAEEGRTARNLIAWSVPLESKDDDGKPKCQTGGKSKRTIQGTH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MMASFQRSNSHDKVRRIVAEEGRTARNLIAWSVPLESKDDDGKPKCQTGGKSKRTIQGTH
10 20 30 40 50 60
60 70 80 90 100 110
pF1KA1 KTTKQSTAVDCKITSSTTGDKHFDKSPTKTRHPRKIDLRARYWAFLFDNLRRAVDEIYVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTTKQSTAVDCKITSSTTGDKHFDKSPTKTRHPRKIDLRARYWAFLFDNLRRAVDEIYVT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KA1 CESDQSVVECKEVLMMLDNYVRDFKALIDWIQLQEKLEKTDAQSRPTSLAWEVKKMSPGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CESDQSVVECKEVLMMLDNYVRDFKALIDWIQLQEKLEKTDAQSRPTSLAWEVKKMSPGR
130 140 150 160 170 180
180 190 200 210 220 230
pF1KA1 HVIPSPSTDRINVTSNARRSLNFGGSTGTVPAPRLAPTGVSWADKVKAHHTGSTASSEIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HVIPSPSTDRINVTSNARRSLNFGGSTGTVPAPRLAPTGVSWADKVKAHHTGSTASSEIT
190 200 210 220 230 240
240 250 260 270 280 290
pF1KA1 PAQSCPPMTVQKASRKNERKDAEGWETVQRGRPIRSRSTAVMPKVSLATEATRSKDDSDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAQSCPPMTVQKASRKNERKDAEGWETVQRGRPIRSRSTAVMPKVSLATEATRSKDDSDK
250 260 270 280 290 300
300 310 320 330 340 350
pF1KA1 ENVCLLPDESIQKGQFVGDGTSNTIESHPKDSLHSCDHPLAEKTQFTVSTLDDVKNSGSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENVCLLPDESIQKGQFVGDGTSNTIESHPKDSLHSCDHPLAEKTQFTVSTLDDVKNSGSI
310 320 330 340 350 360
360 370 380 390 400 410
pF1KA1 RDNYVRTSEISAVHIDTECVSVMLQAGTPPLQVNEEKFPAEKARIENEMDPSDISNSMAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDNYVRTSEISAVHIDTECVSVMLQAGTPPLQVNEEKFPAEKARIENEMDPSDISNSMAE
370 380 390 400 410 420
420 430 440 450 460 470
pF1KA1 VLAKKEELADRLEKANEEAIASAIAEEEQLTREIEAEENNDINIETDNDSDFSASMGSGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLAKKEELADRLEKANEEAIASAIAEEEQLTREIEAEENNDINIETDNDSDFSASMGSGS
430 440 450 460 470 480
480 490 500 510 520 530
pF1KA1 VSFCGMSMDWNDVLADYEARESWRQNTSWGDIVEEEPARPPGHGIHMHEKLSSPSRKRTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSFCGMSMDWNDVLADYEARESWRQNTSWGDIVEEEPARPPGHGIHMHEKLSSPSRKRTI
490 500 510 520 530 540
540 550 560 570 580 590
pF1KA1 AESKKKHEEKQMKAQQLREKLREEKTLKLQKLLEREKDVRKWKEELLDQRRRMMEEKLLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AESKKKHEEKQMKAQQLREKLREEKTLKLQKLLEREKDVRKWKEELLDQRRRMMEEKLLH
550 560 570 580 590 600
600 610 620 630 640 650
pF1KA1 AEFKREVQLQAIVKKAQEEEAKVNEIAFINTLEAQNKRHDVLSKLKEYEQRLNELQEERQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AEFKREVQLQAIVKKAQEEEAKVNEIAFINTLEAQNKRHDVLSKLKEYEQRLNELQEERQ
610 620 630 640 650 660
660 670 680 690 700 710
pF1KA1 RRQEEKQARDEAVQERKRALEAERQARVEELLMKRKEQEARIEQQRQEKEKAREDAARER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRQEEKQARDEAVQERKRALEAERQARVEELLMKRKEQEARIEQQRQEKEKAREDAARER
670 680 690 700 710 720
720 730 740 750 760 770
pF1KA1 ARDREERLAALTAAQQEAMEELQKKIQLKHDESIRRHMEQIEQRKEKAAELSSGRHANTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARDREERLAALTAAQQEAMEELQKKIQLKHDESIRRHMEQIEQRKEKAAELSSGRHANTD
730 740 750 760 770 780
780 790 800 810 820 830
pF1KA1 YAPKLTPYERKKQCSLCNVLISSEVYLFSHVKGRKHQQAVRENTSIQGRELSDEEVEHLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YAPKLTPYERKKQCSLCNVLISSEVYLFSHVKGRKHQQAVRENTSIQGRELSDEEVEHLS
790 800 810 820 830 840
840 850 860 870 880 890
pF1KA1 LKKYIIDIVVESTAPAEALKDGEERQKNKKKAKKIKARMNFRAKEYESLMETKNSGSDSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKKYIIDIVVESTAPAEALKDGEERQKNKKKAKKIKARMNFRAKEYESLMETKNSGSDSP
850 860 870 880 890 900
900 910 920 930 940 950
pF1KA1 YKAKLQRLAKDLLKQVQVQDSGSWANNKVSALDRTLGEITRILEKENVADQIAFQAAGGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YKAKLQRLAKDLLKQVQVQDSGSWANNKVSALDRTLGEITRILEKENVADQIAFQAAGGL
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KA1 TALEHILQAVVPATNVNTVLRIPPKSLCNAINVYNLTCNNCSENCSDVLFSNKITFLMDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TALEHILQAVVPATNVNTVLRIPPKSLCNAINVYNLTCNNCSENCSDVLFSNKITFLMDL
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KA1 LIHQLTVYVPDENNTILGRNTNKQVFEGLTTGLLKVSAVVLGCLIANRPDGNCQPATPKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIHQLTVYVPDENNTILGRNTNKQVFEGLTTGLLKVSAVVLGCLIANRPDGNCQPATPKI
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KA1 PTQEMKNKTSQGDPFNNRVQDLISYVVNMGLIDKLCACFLSVQGPVDENPKMAIFLQHAA
:::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTQEMKNKPSQGDPFNNRVQDLISYVVNMGLIDKLCACFLSVQGPVDENPKMAIFLQHAA
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170 1180 1190
pF1KA1 GLLHAMCTLCFAVTGRSYSIFDNNRQDPTGLTAALQATDLAGVLHMLYCVLFHGTILDPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLLHAMCTLCFAVTGRSYSIFDNNRQDPTGLTAALQATDLAGVLHMLYCVLFHGTILDPS
1150 1160 1170 1180 1190 1200
1200 1210 1220 1230 1240 1250
pF1KA1 TASPKENYTQNTIQVAIQSLRFFNSFAALHLPAFQSIVGAEGLSLAFRHMASSLLGHCSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TASPKENYTQNTIQVAIQSLRFFNSFAALHLPAFQSIVGAEGLSLAFRHMASSLLGHCSQ
1210 1220 1230 1240 1250 1260
1260 1270 1280 1290 1300 1310
pF1KA1 VSCESLLHEVIVCVGYFTVNHPDNQVIVQSGRHPTVLQKLCQLPFQYFSDPRLIKVLFPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSCESLLHEVIVCVGYFTVNHPDNQVIVQSGRHPTVLQKLCQLPFQYFSDPRLIKVLFPS
1270 1280 1290 1300 1310 1320
1320 1330 1340 1350 1360 1370
pF1KA1 LIAACYNNHQNKIILEQEMSCVLLATFIQDLAQTPGQAENQPYQPKGKCLGSQDYLELAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIAACYNNHQNKIILEQEMSCVLLATFIQDLAQTPGQAENQPYQPKGKCLGSQDYLELAN
1330 1340 1350 1360 1370 1380
1380 1390
pF1KA1 RFPQQAWEEARQFFLKKEKK
::::::::::::::::::::
XP_016 RFPQQAWEEARQFFLKKEKK
1390 1400
>>XP_005254476 (OMIM: 611611) PREDICTED: S phase cyclin (1400 aa)
initn: 9144 init1: 9144 opt: 9144 Z-score: 3449.8 bits: 650.8 E(85289): 2e-185
Smith-Waterman score: 9144; 99.9% identity (99.9% similar) in 1399 aa overlap (1-1399:2-1400)
10 20 30 40 50
pF1KA1 MASFQRSNSHDKVRRIVAEEGRTARNLIAWSVPLESKDDDGKPKCQTGGKSKRTIQGTH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MMASFQRSNSHDKVRRIVAEEGRTARNLIAWSVPLESKDDDGKPKCQTGGKSKRTIQGTH
10 20 30 40 50 60
60 70 80 90 100 110
pF1KA1 KTTKQSTAVDCKITSSTTGDKHFDKSPTKTRHPRKIDLRARYWAFLFDNLRRAVDEIYVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KTTKQSTAVDCKITSSTTGDKHFDKSPTKTRHPRKIDLRARYWAFLFDNLRRAVDEIYVT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KA1 CESDQSVVECKEVLMMLDNYVRDFKALIDWIQLQEKLEKTDAQSRPTSLAWEVKKMSPGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CESDQSVVECKEVLMMLDNYVRDFKALIDWIQLQEKLEKTDAQSRPTSLAWEVKKMSPGR
130 140 150 160 170 180
180 190 200 210 220 230
pF1KA1 HVIPSPSTDRINVTSNARRSLNFGGSTGTVPAPRLAPTGVSWADKVKAHHTGSTASSEIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HVIPSPSTDRINVTSNARRSLNFGGSTGTVPAPRLAPTGVSWADKVKAHHTGSTASSEIT
190 200 210 220 230 240
240 250 260 270 280 290
pF1KA1 PAQSCPPMTVQKASRKNERKDAEGWETVQRGRPIRSRSTAVMPKVSLATEATRSKDDSDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PAQSCPPMTVQKASRKNERKDAEGWETVQRGRPIRSRSTAVMPKVSLATEATRSKDDSDK
250 260 270 280 290 300
300 310 320 330 340 350
pF1KA1 ENVCLLPDESIQKGQFVGDGTSNTIESHPKDSLHSCDHPLAEKTQFTVSTLDDVKNSGSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ENVCLLPDESIQKGQFVGDGTSNTIESHPKDSLHSCDHPLAEKTQFTVSTLDDVKNSGSI
310 320 330 340 350 360
360 370 380 390 400 410
pF1KA1 RDNYVRTSEISAVHIDTECVSVMLQAGTPPLQVNEEKFPAEKARIENEMDPSDISNSMAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RDNYVRTSEISAVHIDTECVSVMLQAGTPPLQVNEEKFPAEKARIENEMDPSDISNSMAE
370 380 390 400 410 420
420 430 440 450 460 470
pF1KA1 VLAKKEELADRLEKANEEAIASAIAEEEQLTREIEAEENNDINIETDNDSDFSASMGSGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLAKKEELADRLEKANEEAIASAIAEEEQLTREIEAEENNDINIETDNDSDFSASMGSGS
430 440 450 460 470 480
480 490 500 510 520 530
pF1KA1 VSFCGMSMDWNDVLADYEARESWRQNTSWGDIVEEEPARPPGHGIHMHEKLSSPSRKRTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSFCGMSMDWNDVLADYEARESWRQNTSWGDIVEEEPARPPGHGIHMHEKLSSPSRKRTI
490 500 510 520 530 540
540 550 560 570 580 590
pF1KA1 AESKKKHEEKQMKAQQLREKLREEKTLKLQKLLEREKDVRKWKEELLDQRRRMMEEKLLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AESKKKHEEKQMKAQQLREKLREEKTLKLQKLLEREKDVRKWKEELLDQRRRMMEEKLLH
550 560 570 580 590 600
600 610 620 630 640 650
pF1KA1 AEFKREVQLQAIVKKAQEEEAKVNEIAFINTLEAQNKRHDVLSKLKEYEQRLNELQEERQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AEFKREVQLQAIVKKAQEEEAKVNEIAFINTLEAQNKRHDVLSKLKEYEQRLNELQEERQ
610 620 630 640 650 660
660 670 680 690 700 710
pF1KA1 RRQEEKQARDEAVQERKRALEAERQARVEELLMKRKEQEARIEQQRQEKEKAREDAARER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RRQEEKQARDEAVQERKRALEAERQARVEELLMKRKEQEARIEQQRQEKEKAREDAARER
670 680 690 700 710 720
720 730 740 750 760 770
pF1KA1 ARDREERLAALTAAQQEAMEELQKKIQLKHDESIRRHMEQIEQRKEKAAELSSGRHANTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ARDREERLAALTAAQQEAMEELQKKIQLKHDESIRRHMEQIEQRKEKAAELSSGRHANTD
730 740 750 760 770 780
780 790 800 810 820 830
pF1KA1 YAPKLTPYERKKQCSLCNVLISSEVYLFSHVKGRKHQQAVRENTSIQGRELSDEEVEHLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YAPKLTPYERKKQCSLCNVLISSEVYLFSHVKGRKHQQAVRENTSIQGRELSDEEVEHLS
790 800 810 820 830 840
840 850 860 870 880 890
pF1KA1 LKKYIIDIVVESTAPAEALKDGEERQKNKKKAKKIKARMNFRAKEYESLMETKNSGSDSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKKYIIDIVVESTAPAEALKDGEERQKNKKKAKKIKARMNFRAKEYESLMETKNSGSDSP
850 860 870 880 890 900
900 910 920 930 940 950
pF1KA1 YKAKLQRLAKDLLKQVQVQDSGSWANNKVSALDRTLGEITRILEKENVADQIAFQAAGGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YKAKLQRLAKDLLKQVQVQDSGSWANNKVSALDRTLGEITRILEKENVADQIAFQAAGGL
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KA1 TALEHILQAVVPATNVNTVLRIPPKSLCNAINVYNLTCNNCSENCSDVLFSNKITFLMDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TALEHILQAVVPATNVNTVLRIPPKSLCNAINVYNLTCNNCSENCSDVLFSNKITFLMDL
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KA1 LIHQLTVYVPDENNTILGRNTNKQVFEGLTTGLLKVSAVVLGCLIANRPDGNCQPATPKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LIHQLTVYVPDENNTILGRNTNKQVFEGLTTGLLKVSAVVLGCLIANRPDGNCQPATPKI
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KA1 PTQEMKNKTSQGDPFNNRVQDLISYVVNMGLIDKLCACFLSVQGPVDENPKMAIFLQHAA
:::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PTQEMKNKPSQGDPFNNRVQDLISYVVNMGLIDKLCACFLSVQGPVDENPKMAIFLQHAA
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170 1180 1190
pF1KA1 GLLHAMCTLCFAVTGRSYSIFDNNRQDPTGLTAALQATDLAGVLHMLYCVLFHGTILDPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLLHAMCTLCFAVTGRSYSIFDNNRQDPTGLTAALQATDLAGVLHMLYCVLFHGTILDPS
1150 1160 1170 1180 1190 1200
1200 1210 1220 1230 1240 1250
pF1KA1 TASPKENYTQNTIQVAIQSLRFFNSFAALHLPAFQSIVGAEGLSLAFRHMASSLLGHCSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TASPKENYTQNTIQVAIQSLRFFNSFAALHLPAFQSIVGAEGLSLAFRHMASSLLGHCSQ
1210 1220 1230 1240 1250 1260
1260 1270 1280 1290 1300 1310
pF1KA1 VSCESLLHEVIVCVGYFTVNHPDNQVIVQSGRHPTVLQKLCQLPFQYFSDPRLIKVLFPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSCESLLHEVIVCVGYFTVNHPDNQVIVQSGRHPTVLQKLCQLPFQYFSDPRLIKVLFPS
1270 1280 1290 1300 1310 1320
1320 1330 1340 1350 1360 1370
pF1KA1 LIAACYNNHQNKIILEQEMSCVLLATFIQDLAQTPGQAENQPYQPKGKCLGSQDYLELAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LIAACYNNHQNKIILEQEMSCVLLATFIQDLAQTPGQAENQPYQPKGKCLGSQDYLELAN
1330 1340 1350 1360 1370 1380
1380 1390
pF1KA1 RFPQQAWEEARQFFLKKEKK
::::::::::::::::::::
XP_005 RFPQQAWEEARQFFLKKEKK
1390 1400
>>XP_016877757 (OMIM: 611611) PREDICTED: S phase cyclin (1406 aa)
initn: 6391 init1: 6391 opt: 9122 Z-score: 3441.6 bits: 649.3 E(85289): 5.9e-185
Smith-Waterman score: 9122; 99.5% identity (99.5% similar) in 1405 aa overlap (1-1399:2-1406)
10 20 30 40 50
pF1KA1 MASFQRSNSHDKVRRIVAEEGRTARNLIAWSVPLESKDDDGKPKCQTGGKSKRTIQGTH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MMASFQRSNSHDKVRRIVAEEGRTARNLIAWSVPLESKDDDGKPKCQTGGKSKRTIQGTH
10 20 30 40 50 60
60 70 80 90 100 110
pF1KA1 KTTKQSTAVDCKITSSTTGDKHFDKSPTKTRHPRKIDLRARYWAFLFDNLRRAVDEIYVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTTKQSTAVDCKITSSTTGDKHFDKSPTKTRHPRKIDLRARYWAFLFDNLRRAVDEIYVT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KA1 CESDQSVVECKEVLMMLDNYVRDFKALIDWIQLQEKLEKTDAQSRPTSLAWEVKKMSPGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CESDQSVVECKEVLMMLDNYVRDFKALIDWIQLQEKLEKTDAQSRPTSLAWEVKKMSPGR
130 140 150 160 170 180
180 190 200 210 220 230
pF1KA1 HVIPSPSTDRINVTSNARRSLNFGGSTGTVPAPRLAPTGVSWADKVKAHHTGSTASSEIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HVIPSPSTDRINVTSNARRSLNFGGSTGTVPAPRLAPTGVSWADKVKAHHTGSTASSEIT
190 200 210 220 230 240
240 250 260 270 280 290
pF1KA1 PAQSCPPMTVQKASRKNERKDAEGWETVQRGRPIRSRSTAVMPKVSLATEATRSKDDSDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAQSCPPMTVQKASRKNERKDAEGWETVQRGRPIRSRSTAVMPKVSLATEATRSKDDSDK
250 260 270 280 290 300
300 310 320 330 340 350
pF1KA1 ENVCLLPDESIQKGQFVGDGTSNTIESHPKDSLHSCDHPLAEKTQFTVSTLDDVKNSGSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENVCLLPDESIQKGQFVGDGTSNTIESHPKDSLHSCDHPLAEKTQFTVSTLDDVKNSGSI
310 320 330 340 350 360
360 370 380 390 400 410
pF1KA1 RDNYVRTSEISAVHIDTECVSVMLQAGTPPLQVNEEKFPAEKARIENEMDPSDISN----
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDNYVRTSEISAVHIDTECVSVMLQAGTPPLQVNEEKFPAEKARIENEMDPSDISNVSAA
370 380 390 400 410 420
420 430 440 450 460 470
pF1KA1 --SMAEVLAKKEELADRLEKANEEAIASAIAEEEQLTREIEAEENNDINIETDNDSDFSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLSMAEVLAKKEELADRLEKANEEAIASAIAEEEQLTREIEAEENNDINIETDNDSDFSA
430 440 450 460 470 480
480 490 500 510 520 530
pF1KA1 SMGSGSVSFCGMSMDWNDVLADYEARESWRQNTSWGDIVEEEPARPPGHGIHMHEKLSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SMGSGSVSFCGMSMDWNDVLADYEARESWRQNTSWGDIVEEEPARPPGHGIHMHEKLSSP
490 500 510 520 530 540
540 550 560 570 580 590
pF1KA1 SRKRTIAESKKKHEEKQMKAQQLREKLREEKTLKLQKLLEREKDVRKWKEELLDQRRRMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRKRTIAESKKKHEEKQMKAQQLREKLREEKTLKLQKLLEREKDVRKWKEELLDQRRRMM
550 560 570 580 590 600
600 610 620 630 640 650
pF1KA1 EEKLLHAEFKREVQLQAIVKKAQEEEAKVNEIAFINTLEAQNKRHDVLSKLKEYEQRLNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEKLLHAEFKREVQLQAIVKKAQEEEAKVNEIAFINTLEAQNKRHDVLSKLKEYEQRLNE
610 620 630 640 650 660
660 670 680 690 700 710
pF1KA1 LQEERQRRQEEKQARDEAVQERKRALEAERQARVEELLMKRKEQEARIEQQRQEKEKARE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQEERQRRQEEKQARDEAVQERKRALEAERQARVEELLMKRKEQEARIEQQRQEKEKARE
670 680 690 700 710 720
720 730 740 750 760 770
pF1KA1 DAARERARDREERLAALTAAQQEAMEELQKKIQLKHDESIRRHMEQIEQRKEKAAELSSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DAARERARDREERLAALTAAQQEAMEELQKKIQLKHDESIRRHMEQIEQRKEKAAELSSG
730 740 750 760 770 780
780 790 800 810 820 830
pF1KA1 RHANTDYAPKLTPYERKKQCSLCNVLISSEVYLFSHVKGRKHQQAVRENTSIQGRELSDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RHANTDYAPKLTPYERKKQCSLCNVLISSEVYLFSHVKGRKHQQAVRENTSIQGRELSDE
790 800 810 820 830 840
840 850 860 870 880 890
pF1KA1 EVEHLSLKKYIIDIVVESTAPAEALKDGEERQKNKKKAKKIKARMNFRAKEYESLMETKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVEHLSLKKYIIDIVVESTAPAEALKDGEERQKNKKKAKKIKARMNFRAKEYESLMETKN
850 860 870 880 890 900
900 910 920 930 940 950
pF1KA1 SGSDSPYKAKLQRLAKDLLKQVQVQDSGSWANNKVSALDRTLGEITRILEKENVADQIAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGSDSPYKAKLQRLAKDLLKQVQVQDSGSWANNKVSALDRTLGEITRILEKENVADQIAF
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KA1 QAAGGLTALEHILQAVVPATNVNTVLRIPPKSLCNAINVYNLTCNNCSENCSDVLFSNKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QAAGGLTALEHILQAVVPATNVNTVLRIPPKSLCNAINVYNLTCNNCSENCSDVLFSNKI
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KA1 TFLMDLLIHQLTVYVPDENNTILGRNTNKQVFEGLTTGLLKVSAVVLGCLIANRPDGNCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFLMDLLIHQLTVYVPDENNTILGRNTNKQVFEGLTTGLLKVSAVVLGCLIANRPDGNCQ
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KA1 PATPKIPTQEMKNKTSQGDPFNNRVQDLISYVVNMGLIDKLCACFLSVQGPVDENPKMAI
:::::::::::::: :::::::::::::::::::::::::::::::::::::::::::::
XP_016 PATPKIPTQEMKNKPSQGDPFNNRVQDLISYVVNMGLIDKLCACFLSVQGPVDENPKMAI
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170 1180 1190
pF1KA1 FLQHAAGLLHAMCTLCFAVTGRSYSIFDNNRQDPTGLTAALQATDLAGVLHMLYCVLFHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLQHAAGLLHAMCTLCFAVTGRSYSIFDNNRQDPTGLTAALQATDLAGVLHMLYCVLFHG
1150 1160 1170 1180 1190 1200
1200 1210 1220 1230 1240 1250
pF1KA1 TILDPSTASPKENYTQNTIQVAIQSLRFFNSFAALHLPAFQSIVGAEGLSLAFRHMASSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TILDPSTASPKENYTQNTIQVAIQSLRFFNSFAALHLPAFQSIVGAEGLSLAFRHMASSL
1210 1220 1230 1240 1250 1260
1260 1270 1280 1290 1300 1310
pF1KA1 LGHCSQVSCESLLHEVIVCVGYFTVNHPDNQVIVQSGRHPTVLQKLCQLPFQYFSDPRLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGHCSQVSCESLLHEVIVCVGYFTVNHPDNQVIVQSGRHPTVLQKLCQLPFQYFSDPRLI
1270 1280 1290 1300 1310 1320
1320 1330 1340 1350 1360 1370
pF1KA1 KVLFPSLIAACYNNHQNKIILEQEMSCVLLATFIQDLAQTPGQAENQPYQPKGKCLGSQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVLFPSLIAACYNNHQNKIILEQEMSCVLLATFIQDLAQTPGQAENQPYQPKGKCLGSQD
1330 1340 1350 1360 1370 1380
1380 1390
pF1KA1 YLELANRFPQQAWEEARQFFLKKEKK
::::::::::::::::::::::::::
XP_016 YLELANRFPQQAWEEARQFFLKKEKK
1390 1400
>>XP_005254474 (OMIM: 611611) PREDICTED: S phase cyclin (1406 aa)
initn: 6391 init1: 6391 opt: 9122 Z-score: 3441.6 bits: 649.3 E(85289): 5.9e-185
Smith-Waterman score: 9122; 99.5% identity (99.5% similar) in 1405 aa overlap (1-1399:2-1406)
10 20 30 40 50
pF1KA1 MASFQRSNSHDKVRRIVAEEGRTARNLIAWSVPLESKDDDGKPKCQTGGKSKRTIQGTH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MMASFQRSNSHDKVRRIVAEEGRTARNLIAWSVPLESKDDDGKPKCQTGGKSKRTIQGTH
10 20 30 40 50 60
60 70 80 90 100 110
pF1KA1 KTTKQSTAVDCKITSSTTGDKHFDKSPTKTRHPRKIDLRARYWAFLFDNLRRAVDEIYVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KTTKQSTAVDCKITSSTTGDKHFDKSPTKTRHPRKIDLRARYWAFLFDNLRRAVDEIYVT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KA1 CESDQSVVECKEVLMMLDNYVRDFKALIDWIQLQEKLEKTDAQSRPTSLAWEVKKMSPGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CESDQSVVECKEVLMMLDNYVRDFKALIDWIQLQEKLEKTDAQSRPTSLAWEVKKMSPGR
130 140 150 160 170 180
180 190 200 210 220 230
pF1KA1 HVIPSPSTDRINVTSNARRSLNFGGSTGTVPAPRLAPTGVSWADKVKAHHTGSTASSEIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HVIPSPSTDRINVTSNARRSLNFGGSTGTVPAPRLAPTGVSWADKVKAHHTGSTASSEIT
190 200 210 220 230 240
240 250 260 270 280 290
pF1KA1 PAQSCPPMTVQKASRKNERKDAEGWETVQRGRPIRSRSTAVMPKVSLATEATRSKDDSDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PAQSCPPMTVQKASRKNERKDAEGWETVQRGRPIRSRSTAVMPKVSLATEATRSKDDSDK
250 260 270 280 290 300
300 310 320 330 340 350
pF1KA1 ENVCLLPDESIQKGQFVGDGTSNTIESHPKDSLHSCDHPLAEKTQFTVSTLDDVKNSGSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ENVCLLPDESIQKGQFVGDGTSNTIESHPKDSLHSCDHPLAEKTQFTVSTLDDVKNSGSI
310 320 330 340 350 360
360 370 380 390 400 410
pF1KA1 RDNYVRTSEISAVHIDTECVSVMLQAGTPPLQVNEEKFPAEKARIENEMDPSDISN----
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RDNYVRTSEISAVHIDTECVSVMLQAGTPPLQVNEEKFPAEKARIENEMDPSDISNVSAA
370 380 390 400 410 420
420 430 440 450 460 470
pF1KA1 --SMAEVLAKKEELADRLEKANEEAIASAIAEEEQLTREIEAEENNDINIETDNDSDFSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NLSMAEVLAKKEELADRLEKANEEAIASAIAEEEQLTREIEAEENNDINIETDNDSDFSA
430 440 450 460 470 480
480 490 500 510 520 530
pF1KA1 SMGSGSVSFCGMSMDWNDVLADYEARESWRQNTSWGDIVEEEPARPPGHGIHMHEKLSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SMGSGSVSFCGMSMDWNDVLADYEARESWRQNTSWGDIVEEEPARPPGHGIHMHEKLSSP
490 500 510 520 530 540
540 550 560 570 580 590
pF1KA1 SRKRTIAESKKKHEEKQMKAQQLREKLREEKTLKLQKLLEREKDVRKWKEELLDQRRRMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SRKRTIAESKKKHEEKQMKAQQLREKLREEKTLKLQKLLEREKDVRKWKEELLDQRRRMM
550 560 570 580 590 600
600 610 620 630 640 650
pF1KA1 EEKLLHAEFKREVQLQAIVKKAQEEEAKVNEIAFINTLEAQNKRHDVLSKLKEYEQRLNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEKLLHAEFKREVQLQAIVKKAQEEEAKVNEIAFINTLEAQNKRHDVLSKLKEYEQRLNE
610 620 630 640 650 660
660 670 680 690 700 710
pF1KA1 LQEERQRRQEEKQARDEAVQERKRALEAERQARVEELLMKRKEQEARIEQQRQEKEKARE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LQEERQRRQEEKQARDEAVQERKRALEAERQARVEELLMKRKEQEARIEQQRQEKEKARE
670 680 690 700 710 720
720 730 740 750 760 770
pF1KA1 DAARERARDREERLAALTAAQQEAMEELQKKIQLKHDESIRRHMEQIEQRKEKAAELSSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DAARERARDREERLAALTAAQQEAMEELQKKIQLKHDESIRRHMEQIEQRKEKAAELSSG
730 740 750 760 770 780
780 790 800 810 820 830
pF1KA1 RHANTDYAPKLTPYERKKQCSLCNVLISSEVYLFSHVKGRKHQQAVRENTSIQGRELSDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RHANTDYAPKLTPYERKKQCSLCNVLISSEVYLFSHVKGRKHQQAVRENTSIQGRELSDE
790 800 810 820 830 840
840 850 860 870 880 890
pF1KA1 EVEHLSLKKYIIDIVVESTAPAEALKDGEERQKNKKKAKKIKARMNFRAKEYESLMETKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVEHLSLKKYIIDIVVESTAPAEALKDGEERQKNKKKAKKIKARMNFRAKEYESLMETKN
850 860 870 880 890 900
900 910 920 930 940 950
pF1KA1 SGSDSPYKAKLQRLAKDLLKQVQVQDSGSWANNKVSALDRTLGEITRILEKENVADQIAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SGSDSPYKAKLQRLAKDLLKQVQVQDSGSWANNKVSALDRTLGEITRILEKENVADQIAF
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KA1 QAAGGLTALEHILQAVVPATNVNTVLRIPPKSLCNAINVYNLTCNNCSENCSDVLFSNKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QAAGGLTALEHILQAVVPATNVNTVLRIPPKSLCNAINVYNLTCNNCSENCSDVLFSNKI
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KA1 TFLMDLLIHQLTVYVPDENNTILGRNTNKQVFEGLTTGLLKVSAVVLGCLIANRPDGNCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TFLMDLLIHQLTVYVPDENNTILGRNTNKQVFEGLTTGLLKVSAVVLGCLIANRPDGNCQ
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KA1 PATPKIPTQEMKNKTSQGDPFNNRVQDLISYVVNMGLIDKLCACFLSVQGPVDENPKMAI
:::::::::::::: :::::::::::::::::::::::::::::::::::::::::::::
XP_005 PATPKIPTQEMKNKPSQGDPFNNRVQDLISYVVNMGLIDKLCACFLSVQGPVDENPKMAI
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170 1180 1190
pF1KA1 FLQHAAGLLHAMCTLCFAVTGRSYSIFDNNRQDPTGLTAALQATDLAGVLHMLYCVLFHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FLQHAAGLLHAMCTLCFAVTGRSYSIFDNNRQDPTGLTAALQATDLAGVLHMLYCVLFHG
1150 1160 1170 1180 1190 1200
1200 1210 1220 1230 1240 1250
pF1KA1 TILDPSTASPKENYTQNTIQVAIQSLRFFNSFAALHLPAFQSIVGAEGLSLAFRHMASSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TILDPSTASPKENYTQNTIQVAIQSLRFFNSFAALHLPAFQSIVGAEGLSLAFRHMASSL
1210 1220 1230 1240 1250 1260
1260 1270 1280 1290 1300 1310
pF1KA1 LGHCSQVSCESLLHEVIVCVGYFTVNHPDNQVIVQSGRHPTVLQKLCQLPFQYFSDPRLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGHCSQVSCESLLHEVIVCVGYFTVNHPDNQVIVQSGRHPTVLQKLCQLPFQYFSDPRLI
1270 1280 1290 1300 1310 1320
1320 1330 1340 1350 1360 1370
pF1KA1 KVLFPSLIAACYNNHQNKIILEQEMSCVLLATFIQDLAQTPGQAENQPYQPKGKCLGSQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KVLFPSLIAACYNNHQNKIILEQEMSCVLLATFIQDLAQTPGQAENQPYQPKGKCLGSQD
1330 1340 1350 1360 1370 1380
1380 1390
pF1KA1 YLELANRFPQQAWEEARQFFLKKEKK
::::::::::::::::::::::::::
XP_005 YLELANRFPQQAWEEARQFFLKKEKK
1390 1400
>>XP_011519952 (OMIM: 611611) PREDICTED: S phase cyclin (1406 aa)
initn: 6391 init1: 6391 opt: 9122 Z-score: 3441.6 bits: 649.3 E(85289): 5.9e-185
Smith-Waterman score: 9122; 99.5% identity (99.5% similar) in 1405 aa overlap (1-1399:2-1406)
10 20 30 40 50
pF1KA1 MASFQRSNSHDKVRRIVAEEGRTARNLIAWSVPLESKDDDGKPKCQTGGKSKRTIQGTH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MMASFQRSNSHDKVRRIVAEEGRTARNLIAWSVPLESKDDDGKPKCQTGGKSKRTIQGTH
10 20 30 40 50 60
60 70 80 90 100 110
pF1KA1 KTTKQSTAVDCKITSSTTGDKHFDKSPTKTRHPRKIDLRARYWAFLFDNLRRAVDEIYVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KTTKQSTAVDCKITSSTTGDKHFDKSPTKTRHPRKIDLRARYWAFLFDNLRRAVDEIYVT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KA1 CESDQSVVECKEVLMMLDNYVRDFKALIDWIQLQEKLEKTDAQSRPTSLAWEVKKMSPGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CESDQSVVECKEVLMMLDNYVRDFKALIDWIQLQEKLEKTDAQSRPTSLAWEVKKMSPGR
130 140 150 160 170 180
180 190 200 210 220 230
pF1KA1 HVIPSPSTDRINVTSNARRSLNFGGSTGTVPAPRLAPTGVSWADKVKAHHTGSTASSEIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HVIPSPSTDRINVTSNARRSLNFGGSTGTVPAPRLAPTGVSWADKVKAHHTGSTASSEIT
190 200 210 220 230 240
240 250 260 270 280 290
pF1KA1 PAQSCPPMTVQKASRKNERKDAEGWETVQRGRPIRSRSTAVMPKVSLATEATRSKDDSDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAQSCPPMTVQKASRKNERKDAEGWETVQRGRPIRSRSTAVMPKVSLATEATRSKDDSDK
250 260 270 280 290 300
300 310 320 330 340 350
pF1KA1 ENVCLLPDESIQKGQFVGDGTSNTIESHPKDSLHSCDHPLAEKTQFTVSTLDDVKNSGSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENVCLLPDESIQKGQFVGDGTSNTIESHPKDSLHSCDHPLAEKTQFTVSTLDDVKNSGSI
310 320 330 340 350 360
360 370 380 390 400 410
pF1KA1 RDNYVRTSEISAVHIDTECVSVMLQAGTPPLQVNEEKFPAEKARIENEMDPSDISN----
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RDNYVRTSEISAVHIDTECVSVMLQAGTPPLQVNEEKFPAEKARIENEMDPSDISNVSAA
370 380 390 400 410 420
420 430 440 450 460 470
pF1KA1 --SMAEVLAKKEELADRLEKANEEAIASAIAEEEQLTREIEAEENNDINIETDNDSDFSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLSMAEVLAKKEELADRLEKANEEAIASAIAEEEQLTREIEAEENNDINIETDNDSDFSA
430 440 450 460 470 480
480 490 500 510 520 530
pF1KA1 SMGSGSVSFCGMSMDWNDVLADYEARESWRQNTSWGDIVEEEPARPPGHGIHMHEKLSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SMGSGSVSFCGMSMDWNDVLADYEARESWRQNTSWGDIVEEEPARPPGHGIHMHEKLSSP
490 500 510 520 530 540
540 550 560 570 580 590
pF1KA1 SRKRTIAESKKKHEEKQMKAQQLREKLREEKTLKLQKLLEREKDVRKWKEELLDQRRRMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRKRTIAESKKKHEEKQMKAQQLREKLREEKTLKLQKLLEREKDVRKWKEELLDQRRRMM
550 560 570 580 590 600
600 610 620 630 640 650
pF1KA1 EEKLLHAEFKREVQLQAIVKKAQEEEAKVNEIAFINTLEAQNKRHDVLSKLKEYEQRLNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEKLLHAEFKREVQLQAIVKKAQEEEAKVNEIAFINTLEAQNKRHDVLSKLKEYEQRLNE
610 620 630 640 650 660
660 670 680 690 700 710
pF1KA1 LQEERQRRQEEKQARDEAVQERKRALEAERQARVEELLMKRKEQEARIEQQRQEKEKARE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQEERQRRQEEKQARDEAVQERKRALEAERQARVEELLMKRKEQEARIEQQRQEKEKARE
670 680 690 700 710 720
720 730 740 750 760 770
pF1KA1 DAARERARDREERLAALTAAQQEAMEELQKKIQLKHDESIRRHMEQIEQRKEKAAELSSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DAARERARDREERLAALTAAQQEAMEELQKKIQLKHDESIRRHMEQIEQRKEKAAELSSG
730 740 750 760 770 780
780 790 800 810 820 830
pF1KA1 RHANTDYAPKLTPYERKKQCSLCNVLISSEVYLFSHVKGRKHQQAVRENTSIQGRELSDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RHANTDYAPKLTPYERKKQCSLCNVLISSEVYLFSHVKGRKHQQAVRENTSIQGRELSDE
790 800 810 820 830 840
840 850 860 870 880 890
pF1KA1 EVEHLSLKKYIIDIVVESTAPAEALKDGEERQKNKKKAKKIKARMNFRAKEYESLMETKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVEHLSLKKYIIDIVVESTAPAEALKDGEERQKNKKKAKKIKARMNFRAKEYESLMETKN
850 860 870 880 890 900
900 910 920 930 940 950
pF1KA1 SGSDSPYKAKLQRLAKDLLKQVQVQDSGSWANNKVSALDRTLGEITRILEKENVADQIAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGSDSPYKAKLQRLAKDLLKQVQVQDSGSWANNKVSALDRTLGEITRILEKENVADQIAF
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KA1 QAAGGLTALEHILQAVVPATNVNTVLRIPPKSLCNAINVYNLTCNNCSENCSDVLFSNKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QAAGGLTALEHILQAVVPATNVNTVLRIPPKSLCNAINVYNLTCNNCSENCSDVLFSNKI
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KA1 TFLMDLLIHQLTVYVPDENNTILGRNTNKQVFEGLTTGLLKVSAVVLGCLIANRPDGNCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TFLMDLLIHQLTVYVPDENNTILGRNTNKQVFEGLTTGLLKVSAVVLGCLIANRPDGNCQ
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KA1 PATPKIPTQEMKNKTSQGDPFNNRVQDLISYVVNMGLIDKLCACFLSVQGPVDENPKMAI
:::::::::::::: :::::::::::::::::::::::::::::::::::::::::::::
XP_011 PATPKIPTQEMKNKPSQGDPFNNRVQDLISYVVNMGLIDKLCACFLSVQGPVDENPKMAI
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170 1180 1190
pF1KA1 FLQHAAGLLHAMCTLCFAVTGRSYSIFDNNRQDPTGLTAALQATDLAGVLHMLYCVLFHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLQHAAGLLHAMCTLCFAVTGRSYSIFDNNRQDPTGLTAALQATDLAGVLHMLYCVLFHG
1150 1160 1170 1180 1190 1200
1200 1210 1220 1230 1240 1250
pF1KA1 TILDPSTASPKENYTQNTIQVAIQSLRFFNSFAALHLPAFQSIVGAEGLSLAFRHMASSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TILDPSTASPKENYTQNTIQVAIQSLRFFNSFAALHLPAFQSIVGAEGLSLAFRHMASSL
1210 1220 1230 1240 1250 1260
1260 1270 1280 1290 1300 1310
pF1KA1 LGHCSQVSCESLLHEVIVCVGYFTVNHPDNQVIVQSGRHPTVLQKLCQLPFQYFSDPRLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGHCSQVSCESLLHEVIVCVGYFTVNHPDNQVIVQSGRHPTVLQKLCQLPFQYFSDPRLI
1270 1280 1290 1300 1310 1320
1320 1330 1340 1350 1360 1370
pF1KA1 KVLFPSLIAACYNNHQNKIILEQEMSCVLLATFIQDLAQTPGQAENQPYQPKGKCLGSQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVLFPSLIAACYNNHQNKIILEQEMSCVLLATFIQDLAQTPGQAENQPYQPKGKCLGSQD
1330 1340 1350 1360 1370 1380
1380 1390
pF1KA1 YLELANRFPQQAWEEARQFFLKKEKK
::::::::::::::::::::::::::
XP_011 YLELANRFPQQAWEEARQFFLKKEKK
1390 1400
>>XP_016877756 (OMIM: 611611) PREDICTED: S phase cyclin (1425 aa)
initn: 8896 init1: 8896 opt: 8896 Z-score: 3356.9 bits: 633.7 E(85289): 3e-180
Smith-Waterman score: 8896; 99.6% identity (99.8% similar) in 1365 aa overlap (35-1399:61-1425)
10 20 30 40 50 60
pF1KA1 QRSNSHDKVRRIVAEEGRTARNLIAWSVPLESKDDDGKPKCQTGGKSKRTIQGTHKTTKQ
:. .:::::::::::::::::::::::::
XP_016 KTALPWRLSSTPFSRSHTPWVYVINDLGIEENLKNDGKPKCQTGGKSKRTIQGTHKTTKQ
40 50 60 70 80 90
70 80 90 100 110 120
pF1KA1 STAVDCKITSSTTGDKHFDKSPTKTRHPRKIDLRARYWAFLFDNLRRAVDEIYVTCESDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STAVDCKITSSTTGDKHFDKSPTKTRHPRKIDLRARYWAFLFDNLRRAVDEIYVTCESDQ
100 110 120 130 140 150
130 140 150 160 170 180
pF1KA1 SVVECKEVLMMLDNYVRDFKALIDWIQLQEKLEKTDAQSRPTSLAWEVKKMSPGRHVIPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVVECKEVLMMLDNYVRDFKALIDWIQLQEKLEKTDAQSRPTSLAWEVKKMSPGRHVIPS
160 170 180 190 200 210
190 200 210 220 230 240
pF1KA1 PSTDRINVTSNARRSLNFGGSTGTVPAPRLAPTGVSWADKVKAHHTGSTASSEITPAQSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSTDRINVTSNARRSLNFGGSTGTVPAPRLAPTGVSWADKVKAHHTGSTASSEITPAQSC
220 230 240 250 260 270
250 260 270 280 290 300
pF1KA1 PPMTVQKASRKNERKDAEGWETVQRGRPIRSRSTAVMPKVSLATEATRSKDDSDKENVCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPMTVQKASRKNERKDAEGWETVQRGRPIRSRSTAVMPKVSLATEATRSKDDSDKENVCL
280 290 300 310 320 330
310 320 330 340 350 360
pF1KA1 LPDESIQKGQFVGDGTSNTIESHPKDSLHSCDHPLAEKTQFTVSTLDDVKNSGSIRDNYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPDESIQKGQFVGDGTSNTIESHPKDSLHSCDHPLAEKTQFTVSTLDDVKNSGSIRDNYV
340 350 360 370 380 390
370 380 390 400 410 420
pF1KA1 RTSEISAVHIDTECVSVMLQAGTPPLQVNEEKFPAEKARIENEMDPSDISNSMAEVLAKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTSEISAVHIDTECVSVMLQAGTPPLQVNEEKFPAEKARIENEMDPSDISNSMAEVLAKK
400 410 420 430 440 450
430 440 450 460 470 480
pF1KA1 EELADRLEKANEEAIASAIAEEEQLTREIEAEENNDINIETDNDSDFSASMGSGSVSFCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EELADRLEKANEEAIASAIAEEEQLTREIEAEENNDINIETDNDSDFSASMGSGSVSFCG
460 470 480 490 500 510
490 500 510 520 530 540
pF1KA1 MSMDWNDVLADYEARESWRQNTSWGDIVEEEPARPPGHGIHMHEKLSSPSRKRTIAESKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSMDWNDVLADYEARESWRQNTSWGDIVEEEPARPPGHGIHMHEKLSSPSRKRTIAESKK
520 530 540 550 560 570
550 560 570 580 590 600
pF1KA1 KHEEKQMKAQQLREKLREEKTLKLQKLLEREKDVRKWKEELLDQRRRMMEEKLLHAEFKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KHEEKQMKAQQLREKLREEKTLKLQKLLEREKDVRKWKEELLDQRRRMMEEKLLHAEFKR
580 590 600 610 620 630
610 620 630 640 650 660
pF1KA1 EVQLQAIVKKAQEEEAKVNEIAFINTLEAQNKRHDVLSKLKEYEQRLNELQEERQRRQEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVQLQAIVKKAQEEEAKVNEIAFINTLEAQNKRHDVLSKLKEYEQRLNELQEERQRRQEE
640 650 660 670 680 690
670 680 690 700 710 720
pF1KA1 KQARDEAVQERKRALEAERQARVEELLMKRKEQEARIEQQRQEKEKAREDAARERARDRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQARDEAVQERKRALEAERQARVEELLMKRKEQEARIEQQRQEKEKAREDAARERARDRE
700 710 720 730 740 750
730 740 750 760 770 780
pF1KA1 ERLAALTAAQQEAMEELQKKIQLKHDESIRRHMEQIEQRKEKAAELSSGRHANTDYAPKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERLAALTAAQQEAMEELQKKIQLKHDESIRRHMEQIEQRKEKAAELSSGRHANTDYAPKL
760 770 780 790 800 810
790 800 810 820 830 840
pF1KA1 TPYERKKQCSLCNVLISSEVYLFSHVKGRKHQQAVRENTSIQGRELSDEEVEHLSLKKYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPYERKKQCSLCNVLISSEVYLFSHVKGRKHQQAVRENTSIQGRELSDEEVEHLSLKKYI
820 830 840 850 860 870
850 860 870 880 890 900
pF1KA1 IDIVVESTAPAEALKDGEERQKNKKKAKKIKARMNFRAKEYESLMETKNSGSDSPYKAKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDIVVESTAPAEALKDGEERQKNKKKAKKIKARMNFRAKEYESLMETKNSGSDSPYKAKL
880 890 900 910 920 930
910 920 930 940 950 960
pF1KA1 QRLAKDLLKQVQVQDSGSWANNKVSALDRTLGEITRILEKENVADQIAFQAAGGLTALEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QRLAKDLLKQVQVQDSGSWANNKVSALDRTLGEITRILEKENVADQIAFQAAGGLTALEH
940 950 960 970 980 990
970 980 990 1000 1010 1020
pF1KA1 ILQAVVPATNVNTVLRIPPKSLCNAINVYNLTCNNCSENCSDVLFSNKITFLMDLLIHQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILQAVVPATNVNTVLRIPPKSLCNAINVYNLTCNNCSENCSDVLFSNKITFLMDLLIHQL
1000 1010 1020 1030 1040 1050
1030 1040 1050 1060 1070 1080
pF1KA1 TVYVPDENNTILGRNTNKQVFEGLTTGLLKVSAVVLGCLIANRPDGNCQPATPKIPTQEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVYVPDENNTILGRNTNKQVFEGLTTGLLKVSAVVLGCLIANRPDGNCQPATPKIPTQEM
1060 1070 1080 1090 1100 1110
1090 1100 1110 1120 1130 1140
pF1KA1 KNKTSQGDPFNNRVQDLISYVVNMGLIDKLCACFLSVQGPVDENPKMAIFLQHAAGLLHA
::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KNKPSQGDPFNNRVQDLISYVVNMGLIDKLCACFLSVQGPVDENPKMAIFLQHAAGLLHA
1120 1130 1140 1150 1160 1170
1150 1160 1170 1180 1190 1200
pF1KA1 MCTLCFAVTGRSYSIFDNNRQDPTGLTAALQATDLAGVLHMLYCVLFHGTILDPSTASPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MCTLCFAVTGRSYSIFDNNRQDPTGLTAALQATDLAGVLHMLYCVLFHGTILDPSTASPK
1180 1190 1200 1210 1220 1230
1210 1220 1230 1240 1250 1260
pF1KA1 ENYTQNTIQVAIQSLRFFNSFAALHLPAFQSIVGAEGLSLAFRHMASSLLGHCSQVSCES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENYTQNTIQVAIQSLRFFNSFAALHLPAFQSIVGAEGLSLAFRHMASSLLGHCSQVSCES
1240 1250 1260 1270 1280 1290
1270 1280 1290 1300 1310 1320
pF1KA1 LLHEVIVCVGYFTVNHPDNQVIVQSGRHPTVLQKLCQLPFQYFSDPRLIKVLFPSLIAAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLHEVIVCVGYFTVNHPDNQVIVQSGRHPTVLQKLCQLPFQYFSDPRLIKVLFPSLIAAC
1300 1310 1320 1330 1340 1350
1330 1340 1350 1360 1370 1380
pF1KA1 YNNHQNKIILEQEMSCVLLATFIQDLAQTPGQAENQPYQPKGKCLGSQDYLELANRFPQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YNNHQNKIILEQEMSCVLLATFIQDLAQTPGQAENQPYQPKGKCLGSQDYLELANRFPQQ
1360 1370 1380 1390 1400 1410
1390
pF1KA1 AWEEARQFFLKKEKK
:::::::::::::::
XP_016 AWEEARQFFLKKEKK
1420
>>XP_011519954 (OMIM: 611611) PREDICTED: S phase cyclin (1390 aa)
initn: 6391 init1: 6391 opt: 8874 Z-score: 3348.8 bits: 632.1 E(85289): 8.6e-180
Smith-Waterman score: 8874; 99.2% identity (99.3% similar) in 1371 aa overlap (35-1399:20-1390)
10 20 30 40 50 60
pF1KA1 QRSNSHDKVRRIVAEEGRTARNLIAWSVPLESKDDDGKPKCQTGGKSKRTIQGTHKTTKQ
:. .:::::::::::::::::::::::::
XP_011 MAAGSHTPWVYVINDLGIEENLKNDGKPKCQTGGKSKRTIQGTHKTTKQ
10 20 30 40
70 80 90 100 110 120
pF1KA1 STAVDCKITSSTTGDKHFDKSPTKTRHPRKIDLRARYWAFLFDNLRRAVDEIYVTCESDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STAVDCKITSSTTGDKHFDKSPTKTRHPRKIDLRARYWAFLFDNLRRAVDEIYVTCESDQ
50 60 70 80 90 100
130 140 150 160 170 180
pF1KA1 SVVECKEVLMMLDNYVRDFKALIDWIQLQEKLEKTDAQSRPTSLAWEVKKMSPGRHVIPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVVECKEVLMMLDNYVRDFKALIDWIQLQEKLEKTDAQSRPTSLAWEVKKMSPGRHVIPS
110 120 130 140 150 160
190 200 210 220 230 240
pF1KA1 PSTDRINVTSNARRSLNFGGSTGTVPAPRLAPTGVSWADKVKAHHTGSTASSEITPAQSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSTDRINVTSNARRSLNFGGSTGTVPAPRLAPTGVSWADKVKAHHTGSTASSEITPAQSC
170 180 190 200 210 220
250 260 270 280 290 300
pF1KA1 PPMTVQKASRKNERKDAEGWETVQRGRPIRSRSTAVMPKVSLATEATRSKDDSDKENVCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPMTVQKASRKNERKDAEGWETVQRGRPIRSRSTAVMPKVSLATEATRSKDDSDKENVCL
230 240 250 260 270 280
310 320 330 340 350 360
pF1KA1 LPDESIQKGQFVGDGTSNTIESHPKDSLHSCDHPLAEKTQFTVSTLDDVKNSGSIRDNYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPDESIQKGQFVGDGTSNTIESHPKDSLHSCDHPLAEKTQFTVSTLDDVKNSGSIRDNYV
290 300 310 320 330 340
370 380 390 400 410
pF1KA1 RTSEISAVHIDTECVSVMLQAGTPPLQVNEEKFPAEKARIENEMDPSDISN------SMA
::::::::::::::::::::::::::::::::::::::::::::::::::: :::
XP_011 RTSEISAVHIDTECVSVMLQAGTPPLQVNEEKFPAEKARIENEMDPSDISNVSAANLSMA
350 360 370 380 390 400
420 430 440 450 460 470
pF1KA1 EVLAKKEELADRLEKANEEAIASAIAEEEQLTREIEAEENNDINIETDNDSDFSASMGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVLAKKEELADRLEKANEEAIASAIAEEEQLTREIEAEENNDINIETDNDSDFSASMGSG
410 420 430 440 450 460
480 490 500 510 520 530
pF1KA1 SVSFCGMSMDWNDVLADYEARESWRQNTSWGDIVEEEPARPPGHGIHMHEKLSSPSRKRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVSFCGMSMDWNDVLADYEARESWRQNTSWGDIVEEEPARPPGHGIHMHEKLSSPSRKRT
470 480 490 500 510 520
540 550 560 570 580 590
pF1KA1 IAESKKKHEEKQMKAQQLREKLREEKTLKLQKLLEREKDVRKWKEELLDQRRRMMEEKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IAESKKKHEEKQMKAQQLREKLREEKTLKLQKLLEREKDVRKWKEELLDQRRRMMEEKLL
530 540 550 560 570 580
600 610 620 630 640 650
pF1KA1 HAEFKREVQLQAIVKKAQEEEAKVNEIAFINTLEAQNKRHDVLSKLKEYEQRLNELQEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HAEFKREVQLQAIVKKAQEEEAKVNEIAFINTLEAQNKRHDVLSKLKEYEQRLNELQEER
590 600 610 620 630 640
660 670 680 690 700 710
pF1KA1 QRRQEEKQARDEAVQERKRALEAERQARVEELLMKRKEQEARIEQQRQEKEKAREDAARE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QRRQEEKQARDEAVQERKRALEAERQARVEELLMKRKEQEARIEQQRQEKEKAREDAARE
650 660 670 680 690 700
720 730 740 750 760 770
pF1KA1 RARDREERLAALTAAQQEAMEELQKKIQLKHDESIRRHMEQIEQRKEKAAELSSGRHANT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RARDREERLAALTAAQQEAMEELQKKIQLKHDESIRRHMEQIEQRKEKAAELSSGRHANT
710 720 730 740 750 760
780 790 800 810 820 830
pF1KA1 DYAPKLTPYERKKQCSLCNVLISSEVYLFSHVKGRKHQQAVRENTSIQGRELSDEEVEHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DYAPKLTPYERKKQCSLCNVLISSEVYLFSHVKGRKHQQAVRENTSIQGRELSDEEVEHL
770 780 790 800 810 820
840 850 860 870 880 890
pF1KA1 SLKKYIIDIVVESTAPAEALKDGEERQKNKKKAKKIKARMNFRAKEYESLMETKNSGSDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLKKYIIDIVVESTAPAEALKDGEERQKNKKKAKKIKARMNFRAKEYESLMETKNSGSDS
830 840 850 860 870 880
900 910 920 930 940 950
pF1KA1 PYKAKLQRLAKDLLKQVQVQDSGSWANNKVSALDRTLGEITRILEKENVADQIAFQAAGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PYKAKLQRLAKDLLKQVQVQDSGSWANNKVSALDRTLGEITRILEKENVADQIAFQAAGG
890 900 910 920 930 940
960 970 980 990 1000 1010
pF1KA1 LTALEHILQAVVPATNVNTVLRIPPKSLCNAINVYNLTCNNCSENCSDVLFSNKITFLMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTALEHILQAVVPATNVNTVLRIPPKSLCNAINVYNLTCNNCSENCSDVLFSNKITFLMD
950 960 970 980 990 1000
1020 1030 1040 1050 1060 1070
pF1KA1 LLIHQLTVYVPDENNTILGRNTNKQVFEGLTTGLLKVSAVVLGCLIANRPDGNCQPATPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLIHQLTVYVPDENNTILGRNTNKQVFEGLTTGLLKVSAVVLGCLIANRPDGNCQPATPK
1010 1020 1030 1040 1050 1060
1080 1090 1100 1110 1120 1130
pF1KA1 IPTQEMKNKTSQGDPFNNRVQDLISYVVNMGLIDKLCACFLSVQGPVDENPKMAIFLQHA
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPTQEMKNKPSQGDPFNNRVQDLISYVVNMGLIDKLCACFLSVQGPVDENPKMAIFLQHA
1070 1080 1090 1100 1110 1120
1140 1150 1160 1170 1180 1190
pF1KA1 AGLLHAMCTLCFAVTGRSYSIFDNNRQDPTGLTAALQATDLAGVLHMLYCVLFHGTILDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGLLHAMCTLCFAVTGRSYSIFDNNRQDPTGLTAALQATDLAGVLHMLYCVLFHGTILDP
1130 1140 1150 1160 1170 1180
1200 1210 1220 1230 1240 1250
pF1KA1 STASPKENYTQNTIQVAIQSLRFFNSFAALHLPAFQSIVGAEGLSLAFRHMASSLLGHCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STASPKENYTQNTIQVAIQSLRFFNSFAALHLPAFQSIVGAEGLSLAFRHMASSLLGHCS
1190 1200 1210 1220 1230 1240
1260 1270 1280 1290 1300 1310
pF1KA1 QVSCESLLHEVIVCVGYFTVNHPDNQVIVQSGRHPTVLQKLCQLPFQYFSDPRLIKVLFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QVSCESLLHEVIVCVGYFTVNHPDNQVIVQSGRHPTVLQKLCQLPFQYFSDPRLIKVLFP
1250 1260 1270 1280 1290 1300
1320 1330 1340 1350 1360 1370
pF1KA1 SLIAACYNNHQNKIILEQEMSCVLLATFIQDLAQTPGQAENQPYQPKGKCLGSQDYLELA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLIAACYNNHQNKIILEQEMSCVLLATFIQDLAQTPGQAENQPYQPKGKCLGSQDYLELA
1310 1320 1330 1340 1350 1360
1380 1390
pF1KA1 NRFPQQAWEEARQFFLKKEKK
:::::::::::::::::::::
XP_011 NRFPQQAWEEARQFFLKKEKK
1370 1380 1390
>>XP_016877755 (OMIM: 611611) PREDICTED: S phase cyclin (1431 aa)
initn: 6391 init1: 6391 opt: 8874 Z-score: 3348.7 bits: 632.1 E(85289): 8.7e-180
Smith-Waterman score: 8874; 99.2% identity (99.3% similar) in 1371 aa overlap (35-1399:61-1431)
10 20 30 40 50 60
pF1KA1 QRSNSHDKVRRIVAEEGRTARNLIAWSVPLESKDDDGKPKCQTGGKSKRTIQGTHKTTKQ
:. .:::::::::::::::::::::::::
XP_016 KTALPWRLSSTPFSRSHTPWVYVINDLGIEENLKNDGKPKCQTGGKSKRTIQGTHKTTKQ
40 50 60 70 80 90
70 80 90 100 110 120
pF1KA1 STAVDCKITSSTTGDKHFDKSPTKTRHPRKIDLRARYWAFLFDNLRRAVDEIYVTCESDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STAVDCKITSSTTGDKHFDKSPTKTRHPRKIDLRARYWAFLFDNLRRAVDEIYVTCESDQ
100 110 120 130 140 150
130 140 150 160 170 180
pF1KA1 SVVECKEVLMMLDNYVRDFKALIDWIQLQEKLEKTDAQSRPTSLAWEVKKMSPGRHVIPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVVECKEVLMMLDNYVRDFKALIDWIQLQEKLEKTDAQSRPTSLAWEVKKMSPGRHVIPS
160 170 180 190 200 210
190 200 210 220 230 240
pF1KA1 PSTDRINVTSNARRSLNFGGSTGTVPAPRLAPTGVSWADKVKAHHTGSTASSEITPAQSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSTDRINVTSNARRSLNFGGSTGTVPAPRLAPTGVSWADKVKAHHTGSTASSEITPAQSC
220 230 240 250 260 270
250 260 270 280 290 300
pF1KA1 PPMTVQKASRKNERKDAEGWETVQRGRPIRSRSTAVMPKVSLATEATRSKDDSDKENVCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPMTVQKASRKNERKDAEGWETVQRGRPIRSRSTAVMPKVSLATEATRSKDDSDKENVCL
280 290 300 310 320 330
310 320 330 340 350 360
pF1KA1 LPDESIQKGQFVGDGTSNTIESHPKDSLHSCDHPLAEKTQFTVSTLDDVKNSGSIRDNYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPDESIQKGQFVGDGTSNTIESHPKDSLHSCDHPLAEKTQFTVSTLDDVKNSGSIRDNYV
340 350 360 370 380 390
370 380 390 400 410
pF1KA1 RTSEISAVHIDTECVSVMLQAGTPPLQVNEEKFPAEKARIENEMDPSDISN------SMA
::::::::::::::::::::::::::::::::::::::::::::::::::: :::
XP_016 RTSEISAVHIDTECVSVMLQAGTPPLQVNEEKFPAEKARIENEMDPSDISNVSAANLSMA
400 410 420 430 440 450
420 430 440 450 460 470
pF1KA1 EVLAKKEELADRLEKANEEAIASAIAEEEQLTREIEAEENNDINIETDNDSDFSASMGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVLAKKEELADRLEKANEEAIASAIAEEEQLTREIEAEENNDINIETDNDSDFSASMGSG
460 470 480 490 500 510
480 490 500 510 520 530
pF1KA1 SVSFCGMSMDWNDVLADYEARESWRQNTSWGDIVEEEPARPPGHGIHMHEKLSSPSRKRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVSFCGMSMDWNDVLADYEARESWRQNTSWGDIVEEEPARPPGHGIHMHEKLSSPSRKRT
520 530 540 550 560 570
540 550 560 570 580 590
pF1KA1 IAESKKKHEEKQMKAQQLREKLREEKTLKLQKLLEREKDVRKWKEELLDQRRRMMEEKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IAESKKKHEEKQMKAQQLREKLREEKTLKLQKLLEREKDVRKWKEELLDQRRRMMEEKLL
580 590 600 610 620 630
600 610 620 630 640 650
pF1KA1 HAEFKREVQLQAIVKKAQEEEAKVNEIAFINTLEAQNKRHDVLSKLKEYEQRLNELQEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HAEFKREVQLQAIVKKAQEEEAKVNEIAFINTLEAQNKRHDVLSKLKEYEQRLNELQEER
640 650 660 670 680 690
660 670 680 690 700 710
pF1KA1 QRRQEEKQARDEAVQERKRALEAERQARVEELLMKRKEQEARIEQQRQEKEKAREDAARE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QRRQEEKQARDEAVQERKRALEAERQARVEELLMKRKEQEARIEQQRQEKEKAREDAARE
700 710 720 730 740 750
720 730 740 750 760 770
pF1KA1 RARDREERLAALTAAQQEAMEELQKKIQLKHDESIRRHMEQIEQRKEKAAELSSGRHANT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RARDREERLAALTAAQQEAMEELQKKIQLKHDESIRRHMEQIEQRKEKAAELSSGRHANT
760 770 780 790 800 810
780 790 800 810 820 830
pF1KA1 DYAPKLTPYERKKQCSLCNVLISSEVYLFSHVKGRKHQQAVRENTSIQGRELSDEEVEHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DYAPKLTPYERKKQCSLCNVLISSEVYLFSHVKGRKHQQAVRENTSIQGRELSDEEVEHL
820 830 840 850 860 870
840 850 860 870 880 890
pF1KA1 SLKKYIIDIVVESTAPAEALKDGEERQKNKKKAKKIKARMNFRAKEYESLMETKNSGSDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLKKYIIDIVVESTAPAEALKDGEERQKNKKKAKKIKARMNFRAKEYESLMETKNSGSDS
880 890 900 910 920 930
900 910 920 930 940 950
pF1KA1 PYKAKLQRLAKDLLKQVQVQDSGSWANNKVSALDRTLGEITRILEKENVADQIAFQAAGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PYKAKLQRLAKDLLKQVQVQDSGSWANNKVSALDRTLGEITRILEKENVADQIAFQAAGG
940 950 960 970 980 990
960 970 980 990 1000 1010
pF1KA1 LTALEHILQAVVPATNVNTVLRIPPKSLCNAINVYNLTCNNCSENCSDVLFSNKITFLMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTALEHILQAVVPATNVNTVLRIPPKSLCNAINVYNLTCNNCSENCSDVLFSNKITFLMD
1000 1010 1020 1030 1040 1050
1020 1030 1040 1050 1060 1070
pF1KA1 LLIHQLTVYVPDENNTILGRNTNKQVFEGLTTGLLKVSAVVLGCLIANRPDGNCQPATPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLIHQLTVYVPDENNTILGRNTNKQVFEGLTTGLLKVSAVVLGCLIANRPDGNCQPATPK
1060 1070 1080 1090 1100 1110
1080 1090 1100 1110 1120 1130
pF1KA1 IPTQEMKNKTSQGDPFNNRVQDLISYVVNMGLIDKLCACFLSVQGPVDENPKMAIFLQHA
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPTQEMKNKPSQGDPFNNRVQDLISYVVNMGLIDKLCACFLSVQGPVDENPKMAIFLQHA
1120 1130 1140 1150 1160 1170
1140 1150 1160 1170 1180 1190
pF1KA1 AGLLHAMCTLCFAVTGRSYSIFDNNRQDPTGLTAALQATDLAGVLHMLYCVLFHGTILDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGLLHAMCTLCFAVTGRSYSIFDNNRQDPTGLTAALQATDLAGVLHMLYCVLFHGTILDP
1180 1190 1200 1210 1220 1230
1200 1210 1220 1230 1240 1250
pF1KA1 STASPKENYTQNTIQVAIQSLRFFNSFAALHLPAFQSIVGAEGLSLAFRHMASSLLGHCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STASPKENYTQNTIQVAIQSLRFFNSFAALHLPAFQSIVGAEGLSLAFRHMASSLLGHCS
1240 1250 1260 1270 1280 1290
1260 1270 1280 1290 1300 1310
pF1KA1 QVSCESLLHEVIVCVGYFTVNHPDNQVIVQSGRHPTVLQKLCQLPFQYFSDPRLIKVLFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVSCESLLHEVIVCVGYFTVNHPDNQVIVQSGRHPTVLQKLCQLPFQYFSDPRLIKVLFP
1300 1310 1320 1330 1340 1350
1320 1330 1340 1350 1360 1370
pF1KA1 SLIAACYNNHQNKIILEQEMSCVLLATFIQDLAQTPGQAENQPYQPKGKCLGSQDYLELA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLIAACYNNHQNKIILEQEMSCVLLATFIQDLAQTPGQAENQPYQPKGKCLGSQDYLELA
1360 1370 1380 1390 1400 1410
1380 1390
pF1KA1 NRFPQQAWEEARQFFLKKEKK
:::::::::::::::::::::
XP_016 NRFPQQAWEEARQFFLKKEKK
1420 1430
1399 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 20:04:53 2016 done: Thu Nov 3 20:04:56 2016
Total Scan time: 16.180 Total Display time: 0.800
Function used was FASTA [36.3.4 Apr, 2011]