FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1464, 620 aa 1>>>pF1KA1464 620 - 620 aa - 620 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.4368+/-0.000875; mu= 0.9762+/- 0.053 mean_var=210.6540+/-42.453, 0's: 0 Z-trim(113.9): 23 B-trim: 11 in 1/53 Lambda= 0.088367 statistics sampled from 14447 (14460) to 14447 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.758), E-opt: 0.2 (0.444), width: 16 Scan time: 4.260 The best scores are: opt bits E(32554) CCDS32469.1 RANBP10 gene_id:57610|Hs108|chr16 ( 620) 4229 551.8 9.5e-157 CCDS4529.1 RANBP9 gene_id:10048|Hs108|chr6 ( 729) 2815 371.6 2e-102 CCDS81999.1 RANBP10 gene_id:57610|Hs108|chr16 ( 594) 1748 235.5 1.5e-61 >>CCDS32469.1 RANBP10 gene_id:57610|Hs108|chr16 (620 aa) initn: 4229 init1: 4229 opt: 4229 Z-score: 2927.6 bits: 551.8 E(32554): 9.5e-157 Smith-Waterman score: 4229; 100.0% identity (100.0% similar) in 620 aa overlap (1-620:1-620) 10 20 30 40 50 60 pF1KA1 MAAATADPGAGNPQPGDSSGGGAGGGLPSPGEQELSRRLQRLYPAVNQQETPLPRSWSPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 MAAATADPGAGNPQPGDSSGGGAGGGLPSPGEQELSRRLQRLYPAVNQQETPLPRSWSPK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 DKYNYIGLSQGNLRVHYKGHGKNHKDAASVRATHPIPAACGIYYFEVKIVSKGRDGYMGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 DKYNYIGLSQGNLRVHYKGHGKNHKDAASVRATHPIPAACGIYYFEVKIVSKGRDGYMGI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 GLSAQGVNMNRLPGWDKHSYGYHGDDGHSFCSSGTGQPYGPTFTTGDVIGCCVNLINGTC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 GLSAQGVNMNRLPGWDKHSYGYHGDDGHSFCSSGTGQPYGPTFTTGDVIGCCVNLINGTC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 FYTKNGHSLGIAFTDLPANLYPTVGLQTPGEIVDANFGQQPFLFDIEDYMREWRAKVQGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 FYTKNGHSLGIAFTDLPANLYPTVGLQTPGEIVDANFGQQPFLFDIEDYMREWRAKVQGT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 VHCFPISARLGEWQAVLQNMVSSYLVHHGYCATATAFARMTETPIQEEQASIKNRQKIQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 VHCFPISARLGEWQAVLQNMVSSYLVHHGYCATATAFARMTETPIQEEQASIKNRQKIQK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 LVLEGRVGEAIETTQRFYPGLLEHNPNLLFMLKCRQFVEMVNGTDSEVRSLSSRSPKSQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 LVLEGRVGEAIETTQRFYPGLLEHNPNLLFMLKCRQFVEMVNGTDSEVRSLSSRSPKSQD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 SYPGSPSLSPRHGPSSSHMHNTGADSPSCSNGVASTKSKQNHSKYPAPSSSSSSSSSSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 SYPGSPSLSPRHGPSSSHMHNTGADSPSCSNGVASTKSKQNHSKYPAPSSSSSSSSSSSS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 SSPSSVNYSESNSTDSTKSQHHSSTSNQETSDSEMEMEAEHYPNGVLGSMSTRIVNGAYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 SSPSSVNYSESNSTDSTKSQHHSSTSNQETSDSEMEMEAEHYPNGVLGSMSTRIVNGAYK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 HEDLQTDESSMDDRHPRRQLCGGNQAATERIILFGRELQALSEQLGREYGKNLAHTEMLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 HEDLQTDESSMDDRHPRRQLCGGNQAATERIILFGRELQALSEQLGREYGKNLAHTEMLQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 DAFSLLAYSDPWSCPVGQQLDPIQREPVCAALNSAILESQNLPKQPPLMLALGQASECLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 DAFSLLAYSDPWSCPVGQQLDPIQREPVCAALNSAILESQNLPKQPPLMLALGQASECLR 550 560 570 580 590 600 610 620 pF1KA1 LMARAGLGSCSFARVDDYLH :::::::::::::::::::: CCDS32 LMARAGLGSCSFARVDDYLH 610 620 >>CCDS4529.1 RANBP9 gene_id:10048|Hs108|chr6 (729 aa) initn: 2826 init1: 2002 opt: 2815 Z-score: 1952.3 bits: 371.6 E(32554): 2e-102 Smith-Waterman score: 2835; 66.3% identity (81.2% similar) in 658 aa overlap (3-620:93-729) 10 20 30 pF1KA1 MAAATADPGAGNPQP-GDSSGGGAGGGLPSPG :..: :..: : : : ..: : .:: :.:. CCDS45 AAAALLLHPPPPPPPATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAGPGPAGGAPTPA 70 80 90 100 110 120 40 50 60 70 pF1KA1 ---------------------EQELSRRLQRLYPAVNQQETPLPRSWSPKDKYNYIGLSQ :.::.:::.::::::..::::::::::::::..:::::: CCDS45 LVAGSSAAAPFPHGDSALNEQEKELQRRLKRLYPAVDEQETPLPRSWSPKDKFSYIGLSQ 130 140 150 160 170 180 80 90 100 110 120 130 pF1KA1 GNLRVHYKGHGKNHKDAASVRATHPIPAACGIYYFEVKIVSKGRDGYMGIGLSAQGVNMN .:::::::::::. :::::::::::::::::::::::::::::::::::::::::::::: CCDS45 NNLRVHYKGHGKTPKDAASVRATHPIPAACGIYYFEVKIVSKGRDGYMGIGLSAQGVNMN 190 200 210 220 230 240 140 150 160 170 180 190 pF1KA1 RLPGWDKHSYGYHGDDGHSFCSSGTGQPYGPTFTTGDVIGCCVNLINGTCFYTKNGHSLG :::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::: CCDS45 RLPGWDKHSYGYHGDDGHSFCSSGTGQPYGPTFTTGDVIGCCVNLINNTCFYTKNGHSLG 250 260 270 280 290 300 200 210 220 230 240 250 pF1KA1 IAFTDLPANLYPTVGLQTPGEIVDANFGQQPFLFDIEDYMREWRAKVQGTVHCFPISARL ::::::: :::::::::::::.:::::::.::.:::::::::::.:.:. . :::. : CCDS45 IAFTDLPPNLYPTVGLQTPGEVVDANFGQHPFVFDIEDYMREWRTKIQAQIDRFPIGDRE 310 320 330 340 350 360 260 270 280 290 300 310 pF1KA1 GEWQAVLQNMVSSYLVHHGYCATATAFARMTETPIQEEQASIKNRQKIQKLVLEGRVGEA ::::...:.::::::::::::::: :::: :. . :: :::::::.:::::: ::.::: CCDS45 GEWQTMIQKMVSSYLVHHGYCATAEAFARSTDQTVLEELASIKNRQRIQKLVLAGRMGEA 370 380 390 400 410 420 320 330 340 350 360 pF1KA1 IETTQRFYPGLLEHNPNLLFMLKCRQFVEMVNGTDSEVRSLSSRSPKSQDSYP------G :::::..::.:::.:::::: :: :::.::::::::::: :..:::::::::: . CCDS45 IETTQQLYPSLLERNPNLLFTLKVRQFIEMVNGTDSEVRCLGGRSPKSQDSYPVSPRPFS 430 440 450 460 470 480 370 380 390 400 410 pF1KA1 SPSLSPRHGPSSSHMHN--TGADSP-------SCSNGVASTKSKQNHSKYPAPSSSSSSS :::.:: :: ..:: .: : :::::: :.:..:.. . CCDS45 SPSMSPSHG---MNIHNLASGKGSTAHFSGFESCSNGVISNKAHQSYCH----------- 490 500 510 520 420 430 440 450 460 470 pF1KA1 SSSSSSSPSSVNYSESNSTDSTKSQHHSSTSNQETSDSEMEMEAEHYPNGVLGSMSTRIV :.. . :..: : :: . ..::. :. ::. ...::..:: ::: . :. .. CCDS45 --SNKHQSSNLNVPELNSINMSRSQQ----VNNFTSN-DVDMETDHYSNGVGETSSNGFL 530 540 550 560 570 580 480 490 500 510 520 530 pF1KA1 NGAYKHEDLQTD---ESSMDDRHPRRQLCGGNQAATERIILFGRELQALSEQLGREYGKN ::. ::. . : : .:. . :::::::.::: ::.: :::::::.:::: :. ::: CCDS45 NGSSKHDHEMEDCDTEMEVDSSQLRRQLCGGSQAAIERMIHFGRELQAMSEQLRRDCGKN 590 600 610 620 630 640 540 550 560 570 580 590 pF1KA1 LAHTEMLQDAFSLLAYSDPWSCPVGQQLDPIQREPVCAALNSAILESQNLPKQPPLMLAL :. .::.::::::::::::. :::.:::::::::::.::::::::..:::::::: ::. CCDS45 TANKKMLKDAFSLLAYSDPWNSPVGNQLDPIQREPVCSALNSAILETHNLPKQPPLALAM 650 660 670 680 690 700 600 610 620 pF1KA1 GQASECLRLMARAGLGSCSFARVDDYLH :::..:: ::::.:.:::.:: :.:::: CCDS45 GQATQCLGLMARSGIGSCAFATVEDYLH 710 720 >>CCDS81999.1 RANBP10 gene_id:57610|Hs108|chr16 (594 aa) initn: 2971 init1: 1746 opt: 1748 Z-score: 1218.5 bits: 235.5 E(32554): 1.5e-61 Smith-Waterman score: 3609; 86.8% identity (86.8% similar) in 650 aa overlap (1-620:1-594) 10 20 30 40 50 60 pF1KA1 MAAATADPGAGNPQPGDSSGGGAGGGLPSPGEQELSRRLQRLYPAVNQQETPLPRSWSPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 MAAATADPGAGNPQPGDSSGGGAGGGLPSPGEQELSRRLQRLYPAVNQQETPLPRSWSPK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 DKYNYIGLSQGNLRVHYKGHGKNHKDAASVRATHPIPAACGIYYFEVKIVSKGRDGYMGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 DKYNYIGLSQGNLRVHYKGHGKNHKDAASVRATHPIPAACGIYYFEVKIVSKGRDGYMGI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 GLSAQGVNMNRLPGWDKHSYGYHGDDGHSFCSSGTGQPYGPTFTTGDVIGCCVNLINGTC :::::::::::::: CCDS81 GLSAQGVNMNRLPG---------------------------------------------- 130 190 200 210 220 230 240 pF1KA1 FYTKNGHSLGIAFTDLPANLYPTVGLQTPGEIVDANFGQQPFLFDIEDYMREWRAKVQGT :::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 ----------IAFTDLPANLYPTVGLQTPGEIVDANFGQQPFLFDIEDYMREWRAKVQGT 140 150 160 170 180 250 260 270 280 290 300 pF1KA1 VHCFPISARLGEWQAVLQNMVSSYLVHHGYCATATAFARMTETPIQEEQASIKNRQKIQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 VHCFPISARLGEWQAVLQNMVSSYLVHHGYCATATAFARMTETPIQEEQASIKNRQKIQK 190 200 210 220 230 240 310 320 330 340 350 360 pF1KA1 LVLEGRVGEAIETTQRFYPGLLEHNPNLLFMLKCRQFVEMVNGTDSEVRSLSSRSPKSQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 LVLEGRVGEAIETTQRFYPGLLEHNPNLLFMLKCRQFVEMVNGTDSEVRSLSSRSPKSQD 250 260 270 280 290 300 370 380 390 400 410 420 pF1KA1 SYPGSPSLSPRHGPSSSHMHNTGADSPSCSNGVASTKSKQNHSKYPAPSSSSSSSSSSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 SYPGSPSLSPRHGPSSSHMHNTGADSPSCSNGVASTKSKQNHSKYPAPSSSSSSSSSSSS 310 320 330 340 350 360 430 440 450 pF1KA1 SSPSSVNYSESNSTDSTKSQHHSSTSNQETS----------------------------- ::::::::::::::::::::::::::::::: CCDS81 SSPSSVNYSESNSTDSTKSQHHSSTSNQETSNPWLQLERRPNQAAPTTPPGPTPTSTPPH 370 380 390 400 410 420 460 470 480 490 500 510 pF1KA1 -DSEMEMEAEHYPNGVLGSMSTRIVNGAYKHEDLQTDESSMDDRHPRRQLCGGNQAATER ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 SDSEMEMEAEHYPNGVLGSMSTRIVNGAYKHEDLQTDESSMDDRHPRRQLCGGNQAATER 430 440 450 460 470 480 520 530 540 550 560 570 pF1KA1 IILFGRELQALSEQLGREYGKNLAHTEMLQDAFSLLAYSDPWSCPVGQQLDPIQREPVCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 IILFGRELQALSEQLGREYGKNLAHTEMLQDAFSLLAYSDPWSCPVGQQLDPIQREPVCA 490 500 510 520 530 540 580 590 600 610 620 pF1KA1 ALNSAILESQNLPKQPPLMLALGQASECLRLMARAGLGSCSFARVDDYLH :::::::::::::::::::::::::::::::::::::::::::::::::: CCDS81 ALNSAILESQNLPKQPPLMLALGQASECLRLMARAGLGSCSFARVDDYLH 550 560 570 580 590 620 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 21:13:13 2016 done: Wed Nov 2 21:13:14 2016 Total Scan time: 4.260 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]