Result of FASTA (omim) for
pF1KA1478
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA1478, 632 aa
1>>>pF1KA1478 632 - 632 aa - 632 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.0548+/-0.000404; mu= 11.7595+/- 0.025
mean_var=134.0953+/-27.446, 0's: 0 Z-trim(116.0): 404 B-trim: 298 in 1/53
Lambda= 0.110756
statistics sampled from 26396 (26832) to 26396 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.663), E-opt: 0.2 (0.315), width: 16
Scan time: 11.280
The best scores are: opt bits E(85289)
NP_001119576 (OMIM: 604980) rac GTPase-activating ( 632) 4147 674.6 2.9e-193
NP_001306932 (OMIM: 604980) rac GTPase-activating ( 632) 4147 674.6 2.9e-193
XP_011536540 (OMIM: 604980) PREDICTED: rac GTPase- ( 632) 4147 674.6 2.9e-193
XP_006719422 (OMIM: 604980) PREDICTED: rac GTPase- ( 632) 4147 674.6 2.9e-193
NP_001306930 (OMIM: 604980) rac GTPase-activating ( 632) 4147 674.6 2.9e-193
NP_037409 (OMIM: 604980) rac GTPase-activating pro ( 632) 4147 674.6 2.9e-193
NP_001119575 (OMIM: 604980) rac GTPase-activating ( 632) 4147 674.6 2.9e-193
NP_001306928 (OMIM: 604980) rac GTPase-activating ( 632) 4147 674.6 2.9e-193
XP_016874709 (OMIM: 604980) PREDICTED: rac GTPase- ( 632) 4147 674.6 2.9e-193
NP_001306931 (OMIM: 604980) rac GTPase-activating ( 632) 4147 674.6 2.9e-193
NP_001306929 (OMIM: 604980) rac GTPase-activating ( 632) 4147 674.6 2.9e-193
NP_001306933 (OMIM: 604980) rac GTPase-activating ( 632) 4147 674.6 2.9e-193
NP_001306935 (OMIM: 604980) rac GTPase-activating ( 644) 4147 674.6 2.9e-193
NP_001306934 (OMIM: 604980) rac GTPase-activating ( 574) 3765 613.5 6.3e-175
NP_001306936 (OMIM: 604980) rac GTPase-activating ( 558) 3528 575.7 1.5e-163
XP_011536545 (OMIM: 604980) PREDICTED: rac GTPase- ( 558) 3528 575.7 1.5e-163
XP_016874710 (OMIM: 604980) PREDICTED: rac GTPase- ( 558) 3528 575.7 1.5e-163
XP_016874713 (OMIM: 604980) PREDICTED: rac GTPase- ( 558) 3528 575.7 1.5e-163
XP_016874712 (OMIM: 604980) PREDICTED: rac GTPase- ( 558) 3528 575.7 1.5e-163
XP_016874715 (OMIM: 604980) PREDICTED: rac GTPase- ( 558) 3528 575.7 1.5e-163
XP_016874716 (OMIM: 604980) PREDICTED: rac GTPase- ( 558) 3528 575.7 1.5e-163
XP_016874711 (OMIM: 604980) PREDICTED: rac GTPase- ( 558) 3528 575.7 1.5e-163
XP_016874714 (OMIM: 604980) PREDICTED: rac GTPase- ( 558) 3528 575.7 1.5e-163
NP_001193531 (OMIM: 118423,604356) N-chimaerin iso ( 334) 444 82.7 2.3e-15
NP_001813 (OMIM: 118423,604356) N-chimaerin isofor ( 459) 444 82.8 2.9e-15
NP_001020372 (OMIM: 118423,604356) N-chimaerin iso ( 433) 437 81.7 6.1e-15
NP_001035025 (OMIM: 602857) beta-chimaerin isoform ( 332) 421 79.0 2.9e-14
NP_001280000 (OMIM: 602857) beta-chimaerin isoform ( 433) 421 79.1 3.6e-14
NP_001280001 (OMIM: 602857) beta-chimaerin isoform ( 453) 421 79.1 3.7e-14
NP_004058 (OMIM: 602857) beta-chimaerin isoform 2 ( 468) 421 79.1 3.8e-14
NP_001279999 (OMIM: 602857) beta-chimaerin isoform ( 481) 421 79.1 3.9e-14
XP_011513409 (OMIM: 602857) PREDICTED: beta-chimae ( 494) 421 79.2 4e-14
XP_016867211 (OMIM: 602857) PREDICTED: beta-chimae ( 500) 421 79.2 4e-14
NP_001279998 (OMIM: 602857) beta-chimaerin isoform ( 543) 421 79.2 4.3e-14
XP_011513408 (OMIM: 602857) PREDICTED: beta-chimae ( 556) 421 79.2 4.3e-14
XP_011513407 (OMIM: 602857) PREDICTED: beta-chimae ( 569) 421 79.2 4.4e-14
XP_016867210 (OMIM: 602857) PREDICTED: beta-chimae ( 575) 421 79.2 4.5e-14
NP_001280002 (OMIM: 602857) beta-chimaerin isoform ( 287) 414 77.9 5.6e-14
NP_001123537 (OMIM: 602129,609753) unconventional (2022) 423 79.9 9.5e-14
NP_004136 (OMIM: 602129,609753) unconventional myo (2157) 423 79.9 1e-13
NP_001280010 (OMIM: 602857) beta-chimaerin isoform ( 261) 406 76.6 1.3e-13
NP_001243776 (OMIM: 600365) active breakpoint clus ( 310) 357 68.8 3.3e-11
NP_001269078 (OMIM: 600365) active breakpoint clus ( 641) 357 69.0 5.8e-11
NP_001309769 (OMIM: 600365) active breakpoint clus ( 813) 357 69.1 7e-11
NP_001153218 (OMIM: 600365) active breakpoint clus ( 813) 357 69.1 7e-11
NP_001083 (OMIM: 600365) active breakpoint cluster ( 822) 357 69.1 7.1e-11
NP_068781 (OMIM: 600365) active breakpoint cluster ( 859) 357 69.1 7.3e-11
XP_011538307 (OMIM: 610585) PREDICTED: rho GTPase- ( 624) 353 68.4 8.9e-11
XP_005270071 (OMIM: 610585) PREDICTED: rho GTPase- ( 624) 353 68.4 8.9e-11
XP_005268459 (OMIM: 605370,607785) PREDICTED: rho ( 722) 354 68.6 8.9e-11
>>NP_001119576 (OMIM: 604980) rac GTPase-activating prot (632 aa)
initn: 4147 init1: 4147 opt: 4147 Z-score: 3590.8 bits: 674.6 E(85289): 2.9e-193
Smith-Waterman score: 4147; 100.0% identity (100.0% similar) in 632 aa overlap (1-632:1-632)
10 20 30 40 50 60
pF1KA1 MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS
550 560 570 580 590 600
610 620 630
pF1KA1 TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK
::::::::::::::::::::::::::::::::
NP_001 TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK
610 620 630
>>NP_001306932 (OMIM: 604980) rac GTPase-activating prot (632 aa)
initn: 4147 init1: 4147 opt: 4147 Z-score: 3590.8 bits: 674.6 E(85289): 2.9e-193
Smith-Waterman score: 4147; 100.0% identity (100.0% similar) in 632 aa overlap (1-632:1-632)
10 20 30 40 50 60
pF1KA1 MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS
550 560 570 580 590 600
610 620 630
pF1KA1 TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK
::::::::::::::::::::::::::::::::
NP_001 TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK
610 620 630
>>XP_011536540 (OMIM: 604980) PREDICTED: rac GTPase-acti (632 aa)
initn: 4147 init1: 4147 opt: 4147 Z-score: 3590.8 bits: 674.6 E(85289): 2.9e-193
Smith-Waterman score: 4147; 100.0% identity (100.0% similar) in 632 aa overlap (1-632:1-632)
10 20 30 40 50 60
pF1KA1 MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS
550 560 570 580 590 600
610 620 630
pF1KA1 TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK
::::::::::::::::::::::::::::::::
XP_011 TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK
610 620 630
>>XP_006719422 (OMIM: 604980) PREDICTED: rac GTPase-acti (632 aa)
initn: 4147 init1: 4147 opt: 4147 Z-score: 3590.8 bits: 674.6 E(85289): 2.9e-193
Smith-Waterman score: 4147; 100.0% identity (100.0% similar) in 632 aa overlap (1-632:1-632)
10 20 30 40 50 60
pF1KA1 MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS
550 560 570 580 590 600
610 620 630
pF1KA1 TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK
::::::::::::::::::::::::::::::::
XP_006 TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK
610 620 630
>>NP_001306930 (OMIM: 604980) rac GTPase-activating prot (632 aa)
initn: 4147 init1: 4147 opt: 4147 Z-score: 3590.8 bits: 674.6 E(85289): 2.9e-193
Smith-Waterman score: 4147; 100.0% identity (100.0% similar) in 632 aa overlap (1-632:1-632)
10 20 30 40 50 60
pF1KA1 MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS
550 560 570 580 590 600
610 620 630
pF1KA1 TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK
::::::::::::::::::::::::::::::::
NP_001 TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK
610 620 630
>>NP_037409 (OMIM: 604980) rac GTPase-activating protein (632 aa)
initn: 4147 init1: 4147 opt: 4147 Z-score: 3590.8 bits: 674.6 E(85289): 2.9e-193
Smith-Waterman score: 4147; 100.0% identity (100.0% similar) in 632 aa overlap (1-632:1-632)
10 20 30 40 50 60
pF1KA1 MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS
550 560 570 580 590 600
610 620 630
pF1KA1 TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK
::::::::::::::::::::::::::::::::
NP_037 TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK
610 620 630
>>NP_001119575 (OMIM: 604980) rac GTPase-activating prot (632 aa)
initn: 4147 init1: 4147 opt: 4147 Z-score: 3590.8 bits: 674.6 E(85289): 2.9e-193
Smith-Waterman score: 4147; 100.0% identity (100.0% similar) in 632 aa overlap (1-632:1-632)
10 20 30 40 50 60
pF1KA1 MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS
550 560 570 580 590 600
610 620 630
pF1KA1 TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK
::::::::::::::::::::::::::::::::
NP_001 TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK
610 620 630
>>NP_001306928 (OMIM: 604980) rac GTPase-activating prot (632 aa)
initn: 4147 init1: 4147 opt: 4147 Z-score: 3590.8 bits: 674.6 E(85289): 2.9e-193
Smith-Waterman score: 4147; 100.0% identity (100.0% similar) in 632 aa overlap (1-632:1-632)
10 20 30 40 50 60
pF1KA1 MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS
550 560 570 580 590 600
610 620 630
pF1KA1 TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK
::::::::::::::::::::::::::::::::
NP_001 TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK
610 620 630
>>XP_016874709 (OMIM: 604980) PREDICTED: rac GTPase-acti (632 aa)
initn: 4147 init1: 4147 opt: 4147 Z-score: 3590.8 bits: 674.6 E(85289): 2.9e-193
Smith-Waterman score: 4147; 100.0% identity (100.0% similar) in 632 aa overlap (1-632:1-632)
10 20 30 40 50 60
pF1KA1 MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS
550 560 570 580 590 600
610 620 630
pF1KA1 TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK
::::::::::::::::::::::::::::::::
XP_016 TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK
610 620 630
>>NP_001306931 (OMIM: 604980) rac GTPase-activating prot (632 aa)
initn: 4147 init1: 4147 opt: 4147 Z-score: 3590.8 bits: 674.6 E(85289): 2.9e-193
Smith-Waterman score: 4147; 100.0% identity (100.0% similar) in 632 aa overlap (1-632:1-632)
10 20 30 40 50 60
pF1KA1 MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS
550 560 570 580 590 600
610 620 630
pF1KA1 TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK
::::::::::::::::::::::::::::::::
NP_001 TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK
610 620 630
632 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 21:16:16 2016 done: Wed Nov 2 21:16:18 2016
Total Scan time: 11.280 Total Display time: 0.130
Function used was FASTA [36.3.4 Apr, 2011]