Result of FASTA (omim) for
pF1KA1480
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA1480, 808 aa
1>>>pF1KA1480 808 - 808 aa - 808 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.9015+/-0.000373; mu= 13.8455+/- 0.023
mean_var=127.6221+/-25.250, 0's: 0 Z-trim(116.9): 110 B-trim: 0 in 0/58
Lambda= 0.113530
statistics sampled from 28407 (28517) to 28407 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.682), E-opt: 0.2 (0.334), width: 16
Scan time: 10.350
The best scores are: opt bits E(85289)
NP_001160132 (OMIM: 300336,300425,300494) neurolig ( 808) 5549 920.8 0
NP_061850 (OMIM: 300336,300425,300494) neuroligin- ( 828) 4485 746.5 1.1e-214
NP_001308205 (OMIM: 300336,300425,300494) neurolig ( 711) 4480 745.6 1.7e-214
XP_006724726 (OMIM: 300336,300425,300494) PREDICTE ( 731) 4480 745.6 1.7e-214
XP_011529276 (OMIM: 300336,300425,300494) PREDICTE ( 731) 4480 745.6 1.7e-214
XP_006724725 (OMIM: 300336,300425,300494) PREDICTE ( 799) 4480 745.7 1.9e-214
NP_851820 (OMIM: 300336,300425,300494) neuroligin- ( 848) 4480 745.7 2e-214
XP_016885180 (OMIM: 300427,300495,300497) PREDICTE ( 816) 4138 689.7 1.4e-197
XP_016885182 (OMIM: 300427,300495,300497) PREDICTE ( 816) 4138 689.7 1.4e-197
XP_016885181 (OMIM: 300427,300495,300497) PREDICTE ( 816) 4138 689.7 1.4e-197
NP_001269074 (OMIM: 300427,300495,300497) neurolig ( 816) 4138 689.7 1.4e-197
NP_065793 (OMIM: 300427,300495,300497) neuroligin- ( 816) 4138 689.7 1.4e-197
NP_001269075 (OMIM: 300427,300495,300497) neurolig ( 816) 4138 689.7 1.4e-197
NP_851849 (OMIM: 300427,300495,300497) neuroligin- ( 816) 4138 689.7 1.4e-197
XP_016885527 (OMIM: 400028) PREDICTED: neuroligin- ( 816) 4086 681.1 5.1e-195
XP_016885523 (OMIM: 400028) PREDICTED: neuroligin- ( 816) 4086 681.1 5.1e-195
NP_055708 (OMIM: 400028) neuroligin-4, Y-linked is ( 816) 4086 681.1 5.1e-195
XP_016885526 (OMIM: 400028) PREDICTED: neuroligin- ( 816) 4086 681.1 5.1e-195
XP_016885524 (OMIM: 400028) PREDICTED: neuroligin- ( 816) 4086 681.1 5.1e-195
XP_016885525 (OMIM: 400028) PREDICTED: neuroligin- ( 816) 4086 681.1 5.1e-195
XP_011543850 (OMIM: 300427,300495,300497) PREDICTE ( 836) 3538 591.4 5.4e-168
XP_016885179 (OMIM: 300427,300495,300497) PREDICTE ( 836) 3538 591.4 5.4e-168
XP_011543849 (OMIM: 300427,300495,300497) PREDICTE ( 836) 3538 591.4 5.4e-168
XP_005274621 (OMIM: 300427,300495,300497) PREDICTE ( 836) 3538 591.4 5.4e-168
XP_005274622 (OMIM: 300427,300495,300497) PREDICTE ( 836) 3538 591.4 5.4e-168
XP_005274623 (OMIM: 300427,300495,300497) PREDICTE ( 836) 3538 591.4 5.4e-168
XP_006724567 (OMIM: 300427,300495,300497) PREDICTE ( 836) 3538 591.4 5.4e-168
XP_006724937 (OMIM: 400028) PREDICTED: neuroligin- ( 836) 3524 589.1 2.7e-167
XP_011529727 (OMIM: 400028) PREDICTED: neuroligin- ( 836) 3524 589.1 2.7e-167
XP_011529732 (OMIM: 400028) PREDICTED: neuroligin- ( 836) 3524 589.1 2.7e-167
XP_011529730 (OMIM: 400028) PREDICTED: neuroligin- ( 836) 3524 589.1 2.7e-167
XP_011529728 (OMIM: 400028) PREDICTED: neuroligin- ( 836) 3524 589.1 2.7e-167
XP_011529731 (OMIM: 400028) PREDICTED: neuroligin- ( 836) 3524 589.1 2.7e-167
XP_011529729 (OMIM: 400028) PREDICTED: neuroligin- ( 836) 3524 589.1 2.7e-167
XP_011529726 (OMIM: 400028) PREDICTED: neuroligin- ( 836) 3524 589.1 2.7e-167
XP_016885528 (OMIM: 400028) PREDICTED: neuroligin- ( 691) 3517 587.9 5.1e-167
NP_001193779 (OMIM: 400028) neuroligin-4, Y-linked ( 648) 3487 583.0 1.5e-165
XP_016885529 (OMIM: 400028) PREDICTED: neuroligin- ( 648) 3487 583.0 1.5e-165
XP_005256801 (OMIM: 606479) PREDICTED: neuroligin- ( 818) 3299 552.2 3.2e-156
XP_016861391 (OMIM: 600568) PREDICTED: neuroligin- ( 814) 3289 550.6 1e-155
XP_005247293 (OMIM: 600568) PREDICTED: neuroligin- ( 814) 3289 550.6 1e-155
XP_016861393 (OMIM: 600568) PREDICTED: neuroligin- ( 814) 3289 550.6 1e-155
XP_016861392 (OMIM: 600568) PREDICTED: neuroligin- ( 814) 3289 550.6 1e-155
NP_065846 (OMIM: 606479) neuroligin-2 precursor [H ( 835) 2783 467.7 9.1e-131
XP_016861386 (OMIM: 600568) PREDICTED: neuroligin- ( 834) 2725 458.2 6.6e-128
XP_016880386 (OMIM: 606479) PREDICTED: neuroligin- ( 656) 2685 451.6 5.1e-126
XP_016885086 (OMIM: 300336,300425,300494) PREDICTE ( 580) 2559 430.9 7.6e-120
XP_005247294 (OMIM: 600568) PREDICTED: neuroligin- ( 671) 2081 352.7 3.1e-96
XP_016861388 (OMIM: 600568) PREDICTED: neuroligin- ( 823) 2081 352.7 3.7e-96
NP_055747 (OMIM: 600568) neuroligin-1 [Homo sapien ( 823) 2081 352.7 3.7e-96
>>NP_001160132 (OMIM: 300336,300425,300494) neuroligin-3 (808 aa)
initn: 5549 init1: 5549 opt: 5549 Z-score: 4917.3 bits: 920.8 E(85289): 0
Smith-Waterman score: 5549; 100.0% identity (100.0% similar) in 808 aa overlap (1-808:1-808)
10 20 30 40 50 60
pF1KA1 MWLRLGPPSLSLSPKPTVGRSLCLTLWFLSLALRASTQAPAPTVNTHFGKLRGARVPLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MWLRLGPPSLSLSPKPTVGRSLCLTLWFLSLALRASTQAPAPTVNTHFGKLRGARVPLPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 EILGPVDQYLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EILGPVDQYLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 VWFTANLDIVATYIQEPNEDCLYLNVYVPTEDDIRDSGAKPVMVYIHGGSYMEGTGNMID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VWFTANLDIVATYIQEPNEDCLYLNVYVPTEDDIRDSGAKPVMVYIHGGSYMEGTGNMID
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 GSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 RITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 NVLDTVDMVDCLRQKSAKELVEQDIQPARYHVAFGPVIDGDVIPDDPEILMEQGEFLNYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NVLDTVDMVDCLRQKSAKELVEQDIQPARYHVAFGPVIDGDVIPDDPEILMEQGEFLNYD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 IMLGVNQGEGLKFVEGVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IMLGVNQGEGLKFVEGVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 WADRDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSPTYFYAFYHHCQSLMKPAWSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WADRDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSPTYFYAFYHHCQSLMKPAWSD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 AAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNKPVPQDTKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNKPVPQDTKF
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 IHTKANRFEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATKVAFWKHLVPHLYNLHDMFHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IHTKANRFEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATKVAFWKHLVPHLYNLHDMFHY
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 TSTTTKVPPPDTTHSSHITRRPNGKTWSTKRPAISPAYSNENAQGSWNGDQDAGPLLVEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSTTTKVPPPDTTHSSHITRRPNGKTWSTKRPAISPAYSNENAQGSWNGDQDAGPLLVEN
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 PRDYSTELSVTIAVGASLLFLNVLAFAALYYRKDKRRQEPLRQPSPQRGAGAPELGAAPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRDYSTELSVTIAVGASLLFLNVLAFAALYYRKDKRRQEPLRQPSPQRGAGAPELGAAPE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 EELAALQLGPTHHECEAGPPHDTLRLTALPDYTLTLRRSPDDIPLMTPNTITMIPNSLVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EELAALQLGPTHHECEAGPPHDTLRLTALPDYTLTLRRSPDDIPLMTPNTITMIPNSLVG
730 740 750 760 770 780
790 800
pF1KA1 LQTLHPYNTFAAGFNSTGLPHSHSTTRV
::::::::::::::::::::::::::::
NP_001 LQTLHPYNTFAAGFNSTGLPHSHSTTRV
790 800
>>NP_061850 (OMIM: 300336,300425,300494) neuroligin-3 is (828 aa)
initn: 4480 init1: 4480 opt: 4485 Z-score: 3975.3 bits: 746.5 E(85289): 1.1e-214
Smith-Waterman score: 5499; 97.6% identity (97.6% similar) in 828 aa overlap (1-808:1-828)
10 20 30 40 50 60
pF1KA1 MWLRLGPPSLSLSPKPTVGRSLCLTLWFLSLALRASTQAPAPTVNTHFGKLRGARVPLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 MWLRLGPPSLSLSPKPTVGRSLCLTLWFLSLALRASTQAPAPTVNTHFGKLRGARVPLPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 EILGPVDQYLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 EILGPVDQYLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLP
70 80 90 100 110 120
130 140 150 160
pF1KA1 VWFTANLDIVATYIQEPNEDCLYLNVYVPTED--------------------DIRDSGAK
:::::::::::::::::::::::::::::::: ::::::::
NP_061 VWFTANLDIVATYIQEPNEDCLYLNVYVPTEDGSGAKKQGEDLADNDGDEDEDIRDSGAK
130 140 150 160 170 180
170 180 190 200 210 220
pF1KA1 PVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 PVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLD
190 200 210 220 230 240
230 240 250 260 270 280
pF1KA1 QIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 QIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSS
250 260 270 280 290 300
290 300 310 320 330 340
pF1KA1 WAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKELVEQDIQPARYHVAFGPVIDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 WAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKELVEQDIQPARYHVAFGPVIDG
310 320 330 340 350 360
350 360 370 380 390 400
pF1KA1 DVIPDDPEILMEQGEFLNYDIMLGVNQGEGLKFVEGVVDPEDGVSGTDFDYSVSNFVDNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 DVIPDDPEILMEQGEFLNYDIMLGVNQGEGLKFVEGVVDPEDGVSGTDFDYSVSNFVDNL
370 380 390 400 410 420
410 420 430 440 450 460
pF1KA1 YGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 YGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSP
430 440 450 460 470 480
470 480 490 500 510 520
pF1KA1 TYFYAFYHHCQSLMKPAWSDAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 TYFYAFYHHCQSLMKPAWSDAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTY
490 500 510 520 530 540
530 540 550 560 570 580
pF1KA1 WTNFAKTGDPNKPVPQDTKFIHTKANRFEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 WTNFAKTGDPNKPVPQDTKFIHTKANRFEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATK
550 560 570 580 590 600
590 600 610 620 630 640
pF1KA1 VAFWKHLVPHLYNLHDMFHYTSTTTKVPPPDTTHSSHITRRPNGKTWSTKRPAISPAYSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 VAFWKHLVPHLYNLHDMFHYTSTTTKVPPPDTTHSSHITRRPNGKTWSTKRPAISPAYSN
610 620 630 640 650 660
650 660 670 680 690 700
pF1KA1 ENAQGSWNGDQDAGPLLVENPRDYSTELSVTIAVGASLLFLNVLAFAALYYRKDKRRQEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 ENAQGSWNGDQDAGPLLVENPRDYSTELSVTIAVGASLLFLNVLAFAALYYRKDKRRQEP
670 680 690 700 710 720
710 720 730 740 750 760
pF1KA1 LRQPSPQRGAGAPELGAAPEEELAALQLGPTHHECEAGPPHDTLRLTALPDYTLTLRRSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 LRQPSPQRGAGAPELGAAPEEELAALQLGPTHHECEAGPPHDTLRLTALPDYTLTLRRSP
730 740 750 760 770 780
770 780 790 800
pF1KA1 DDIPLMTPNTITMIPNSLVGLQTLHPYNTFAAGFNSTGLPHSHSTTRV
::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 DDIPLMTPNTITMIPNSLVGLQTLHPYNTFAAGFNSTGLPHSHSTTRV
790 800 810 820
>>NP_001308205 (OMIM: 300336,300425,300494) neuroligin-3 (711 aa)
initn: 4480 init1: 4480 opt: 4480 Z-score: 3971.8 bits: 745.6 E(85289): 1.7e-214
Smith-Waterman score: 4668; 97.2% identity (97.2% similar) in 711 aa overlap (118-808:1-711)
90 100 110 120 130 140
pF1KA1 EPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLYLNVY
::::::::::::::::::::::::::::::
NP_001 MLPVWFTANLDIVATYIQEPNEDCLYLNVY
10 20 30
150 160 170 180
pF1KA1 VPTED--------------------DIRDSGAKPVMVYIHGGSYMEGTGNMIDGSILASY
::::: :::::::::::::::::::::::::::::::::::
NP_001 VPTEDGSGAKKQGEDLADNDGDEDEDIRDSGAKPVMVYIHGGSYMEGTGNMIDGSILASY
40 50 60 70 80 90
190 200 210 220 230 240
pF1KA1 GNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGS
100 110 120 130 140 150
250 260 270 280 290 300
pF1KA1 GIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGCNVLDTVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGCNVLDTVD
160 170 180 190 200 210
310 320 330 340 350 360
pF1KA1 MVDCLRQKSAKELVEQDIQPARYHVAFGPVIDGDVIPDDPEILMEQGEFLNYDIMLGVNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVDCLRQKSAKELVEQDIQPARYHVAFGPVIDGDVIPDDPEILMEQGEFLNYDIMLGVNQ
220 230 240 250 260 270
370 380 390 400 410 420
pF1KA1 GEGLKFVEGVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADRDNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GEGLKFVEGVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADRDNP
280 290 300 310 320 330
430 440 450 460 470 480
pF1KA1 ETRRKTLVALFTDHQWVEPSVVTADLHARYGSPTYFYAFYHHCQSLMKPAWSDAAHGDEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETRRKTLVALFTDHQWVEPSVVTADLHARYGSPTYFYAFYHHCQSLMKPAWSDAAHGDEV
340 350 360 370 380 390
490 500 510 520 530 540
pF1KA1 PYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKANR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKANR
400 410 420 430 440 450
550 560 570 580 590 600
pF1KA1 FEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATKVAFWKHLVPHLYNLHDMFHYTSTTTKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATKVAFWKHLVPHLYNLHDMFHYTSTTTKV
460 470 480 490 500 510
610 620 630 640 650 660
pF1KA1 PPPDTTHSSHITRRPNGKTWSTKRPAISPAYSNENAQGSWNGDQDAGPLLVENPRDYSTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPPDTTHSSHITRRPNGKTWSTKRPAISPAYSNENAQGSWNGDQDAGPLLVENPRDYSTE
520 530 540 550 560 570
670 680 690 700 710 720
pF1KA1 LSVTIAVGASLLFLNVLAFAALYYRKDKRRQEPLRQPSPQRGAGAPELGAAPEEELAALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSVTIAVGASLLFLNVLAFAALYYRKDKRRQEPLRQPSPQRGAGAPELGAAPEEELAALQ
580 590 600 610 620 630
730 740 750 760 770 780
pF1KA1 LGPTHHECEAGPPHDTLRLTALPDYTLTLRRSPDDIPLMTPNTITMIPNSLVGLQTLHPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGPTHHECEAGPPHDTLRLTALPDYTLTLRRSPDDIPLMTPNTITMIPNSLVGLQTLHPY
640 650 660 670 680 690
790 800
pF1KA1 NTFAAGFNSTGLPHSHSTTRV
:::::::::::::::::::::
NP_001 NTFAAGFNSTGLPHSHSTTRV
700 710
>>XP_006724726 (OMIM: 300336,300425,300494) PREDICTED: n (731 aa)
initn: 4480 init1: 4480 opt: 4480 Z-score: 3971.7 bits: 745.6 E(85289): 1.7e-214
Smith-Waterman score: 4628; 94.5% identity (94.5% similar) in 731 aa overlap (118-808:1-731)
90 100 110 120 130 140
pF1KA1 EPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLYLNVY
::::::::::::::::::::::::::::::
XP_006 MLPVWFTANLDIVATYIQEPNEDCLYLNVY
10 20 30
150 160
pF1KA1 VPTED----------------------------------------DIRDSGAKPVMVYIH
::::: :::::::::::::::
XP_006 VPTEDVKRISKECARKPNKKICRKGGSGAKKQGEDLADNDGDEDEDIRDSGAKPVMVYIH
40 50 60 70 80 90
170 180 190 200 210 220
pF1KA1 GGSYMEGTGNMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GGSYMEGTGNMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRW
100 110 120 130 140 150
230 240 250 260 270 280
pF1KA1 VSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQP
160 170 180 190 200 210
290 300 310 320 330 340
pF1KA1 VKYTSLLADKVGCNVLDTVDMVDCLRQKSAKELVEQDIQPARYHVAFGPVIDGDVIPDDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VKYTSLLADKVGCNVLDTVDMVDCLRQKSAKELVEQDIQPARYHVAFGPVIDGDVIPDDP
220 230 240 250 260 270
350 360 370 380 390 400
pF1KA1 EILMEQGEFLNYDIMLGVNQGEGLKFVEGVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EILMEQGEFLNYDIMLGVNQGEGLKFVEGVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGK
280 290 300 310 320 330
410 420 430 440 450 460
pF1KA1 DTLRETIKFMYTDWADRDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSPTYFYAFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DTLRETIKFMYTDWADRDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSPTYFYAFY
340 350 360 370 380 390
470 480 490 500 510 520
pF1KA1 HHCQSLMKPAWSDAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HHCQSLMKPAWSDAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKT
400 410 420 430 440 450
530 540 550 560 570 580
pF1KA1 GDPNKPVPQDTKFIHTKANRFEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATKVAFWKHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GDPNKPVPQDTKFIHTKANRFEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATKVAFWKHL
460 470 480 490 500 510
590 600 610 620 630 640
pF1KA1 VPHLYNLHDMFHYTSTTTKVPPPDTTHSSHITRRPNGKTWSTKRPAISPAYSNENAQGSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VPHLYNLHDMFHYTSTTTKVPPPDTTHSSHITRRPNGKTWSTKRPAISPAYSNENAQGSW
520 530 540 550 560 570
650 660 670 680 690 700
pF1KA1 NGDQDAGPLLVENPRDYSTELSVTIAVGASLLFLNVLAFAALYYRKDKRRQEPLRQPSPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NGDQDAGPLLVENPRDYSTELSVTIAVGASLLFLNVLAFAALYYRKDKRRQEPLRQPSPQ
580 590 600 610 620 630
710 720 730 740 750 760
pF1KA1 RGAGAPELGAAPEEELAALQLGPTHHECEAGPPHDTLRLTALPDYTLTLRRSPDDIPLMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RGAGAPELGAAPEEELAALQLGPTHHECEAGPPHDTLRLTALPDYTLTLRRSPDDIPLMT
640 650 660 670 680 690
770 780 790 800
pF1KA1 PNTITMIPNSLVGLQTLHPYNTFAAGFNSTGLPHSHSTTRV
:::::::::::::::::::::::::::::::::::::::::
XP_006 PNTITMIPNSLVGLQTLHPYNTFAAGFNSTGLPHSHSTTRV
700 710 720 730
>>XP_011529276 (OMIM: 300336,300425,300494) PREDICTED: n (731 aa)
initn: 4480 init1: 4480 opt: 4480 Z-score: 3971.7 bits: 745.6 E(85289): 1.7e-214
Smith-Waterman score: 4628; 94.5% identity (94.5% similar) in 731 aa overlap (118-808:1-731)
90 100 110 120 130 140
pF1KA1 EPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLYLNVY
::::::::::::::::::::::::::::::
XP_011 MLPVWFTANLDIVATYIQEPNEDCLYLNVY
10 20 30
150 160
pF1KA1 VPTED----------------------------------------DIRDSGAKPVMVYIH
::::: :::::::::::::::
XP_011 VPTEDVKRISKECARKPNKKICRKGGSGAKKQGEDLADNDGDEDEDIRDSGAKPVMVYIH
40 50 60 70 80 90
170 180 190 200 210 220
pF1KA1 GGSYMEGTGNMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGSYMEGTGNMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRW
100 110 120 130 140 150
230 240 250 260 270 280
pF1KA1 VSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQP
160 170 180 190 200 210
290 300 310 320 330 340
pF1KA1 VKYTSLLADKVGCNVLDTVDMVDCLRQKSAKELVEQDIQPARYHVAFGPVIDGDVIPDDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKYTSLLADKVGCNVLDTVDMVDCLRQKSAKELVEQDIQPARYHVAFGPVIDGDVIPDDP
220 230 240 250 260 270
350 360 370 380 390 400
pF1KA1 EILMEQGEFLNYDIMLGVNQGEGLKFVEGVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EILMEQGEFLNYDIMLGVNQGEGLKFVEGVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGK
280 290 300 310 320 330
410 420 430 440 450 460
pF1KA1 DTLRETIKFMYTDWADRDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSPTYFYAFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTLRETIKFMYTDWADRDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSPTYFYAFY
340 350 360 370 380 390
470 480 490 500 510 520
pF1KA1 HHCQSLMKPAWSDAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HHCQSLMKPAWSDAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKT
400 410 420 430 440 450
530 540 550 560 570 580
pF1KA1 GDPNKPVPQDTKFIHTKANRFEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATKVAFWKHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GDPNKPVPQDTKFIHTKANRFEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATKVAFWKHL
460 470 480 490 500 510
590 600 610 620 630 640
pF1KA1 VPHLYNLHDMFHYTSTTTKVPPPDTTHSSHITRRPNGKTWSTKRPAISPAYSNENAQGSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPHLYNLHDMFHYTSTTTKVPPPDTTHSSHITRRPNGKTWSTKRPAISPAYSNENAQGSW
520 530 540 550 560 570
650 660 670 680 690 700
pF1KA1 NGDQDAGPLLVENPRDYSTELSVTIAVGASLLFLNVLAFAALYYRKDKRRQEPLRQPSPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGDQDAGPLLVENPRDYSTELSVTIAVGASLLFLNVLAFAALYYRKDKRRQEPLRQPSPQ
580 590 600 610 620 630
710 720 730 740 750 760
pF1KA1 RGAGAPELGAAPEEELAALQLGPTHHECEAGPPHDTLRLTALPDYTLTLRRSPDDIPLMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGAGAPELGAAPEEELAALQLGPTHHECEAGPPHDTLRLTALPDYTLTLRRSPDDIPLMT
640 650 660 670 680 690
770 780 790 800
pF1KA1 PNTITMIPNSLVGLQTLHPYNTFAAGFNSTGLPHSHSTTRV
:::::::::::::::::::::::::::::::::::::::::
XP_011 PNTITMIPNSLVGLQTLHPYNTFAAGFNSTGLPHSHSTTRV
700 710 720 730
>>XP_006724725 (OMIM: 300336,300425,300494) PREDICTED: n (799 aa)
initn: 4480 init1: 4480 opt: 4480 Z-score: 3971.1 bits: 745.7 E(85289): 1.9e-214
Smith-Waterman score: 4718; 93.9% identity (94.3% similar) in 750 aa overlap (99-808:50-799)
70 80 90 100 110 120
pF1KA1 YLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLPVWFTANLD
.: . .:::::::::::::::::::::::
XP_006 AACVWIFTYAGLSGPEGVPFLKLWCLDDLLSTLLGTLCPQNIHTAVPEVMLPVWFTANLD
20 30 40 50 60 70
130 140 150
pF1KA1 IVATYIQEPNEDCLYLNVYVPTED------------------------------------
::::::::::::::::::::::::
XP_006 IVATYIQEPNEDCLYLNVYVPTEDVKRISKECARKPNKKICRKGGSGAKKQGEDLADNDG
80 90 100 110 120 130
160 170 180 190 200
pF1KA1 ----DIRDSGAKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRVGVLGFLSTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DEDEDIRDSGAKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRVGVLGFLSTG
140 150 160 170 180 190
210 220 230 240 250 260
pF1KA1 DQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQ
200 210 220 230 240 250
270 280 290 300 310 320
pF1KA1 RAIIQSGSALSSWAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKELVEQDIQPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RAIIQSGSALSSWAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKELVEQDIQPA
260 270 280 290 300 310
330 340 350 360 370 380
pF1KA1 RYHVAFGPVIDGDVIPDDPEILMEQGEFLNYDIMLGVNQGEGLKFVEGVVDPEDGVSGTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RYHVAFGPVIDGDVIPDDPEILMEQGEFLNYDIMLGVNQGEGLKFVEGVVDPEDGVSGTD
320 330 340 350 360 370
390 400 410 420 430 440
pF1KA1 FDYSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVALFTDHQWVEPSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FDYSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVALFTDHQWVEPSV
380 390 400 410 420 430
450 460 470 480 490 500
pF1KA1 VTADLHARYGSPTYFYAFYHHCQSLMKPAWSDAAHGDEVPYVFGVPMVGPTDLFPCNFSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VTADLHARYGSPTYFYAFYHHCQSLMKPAWSDAAHGDEVPYVFGVPMVGPTDLFPCNFSK
440 450 460 470 480 490
510 520 530 540 550 560
pF1KA1 NDVMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKANRFEEVAWSKYNPRDQLYLHIGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NDVMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKANRFEEVAWSKYNPRDQLYLHIGL
500 510 520 530 540 550
570 580 590 600 610 620
pF1KA1 KPRVRDHYRATKVAFWKHLVPHLYNLHDMFHYTSTTTKVPPPDTTHSSHITRRPNGKTWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KPRVRDHYRATKVAFWKHLVPHLYNLHDMFHYTSTTTKVPPPDTTHSSHITRRPNGKTWS
560 570 580 590 600 610
630 640 650 660 670 680
pF1KA1 TKRPAISPAYSNENAQGSWNGDQDAGPLLVENPRDYSTELSVTIAVGASLLFLNVLAFAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TKRPAISPAYSNENAQGSWNGDQDAGPLLVENPRDYSTELSVTIAVGASLLFLNVLAFAA
620 630 640 650 660 670
690 700 710 720 730 740
pF1KA1 LYYRKDKRRQEPLRQPSPQRGAGAPELGAAPEEELAALQLGPTHHECEAGPPHDTLRLTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LYYRKDKRRQEPLRQPSPQRGAGAPELGAAPEEELAALQLGPTHHECEAGPPHDTLRLTA
680 690 700 710 720 730
750 760 770 780 790 800
pF1KA1 LPDYTLTLRRSPDDIPLMTPNTITMIPNSLVGLQTLHPYNTFAAGFNSTGLPHSHSTTRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LPDYTLTLRRSPDDIPLMTPNTITMIPNSLVGLQTLHPYNTFAAGFNSTGLPHSHSTTRV
740 750 760 770 780 790
>>NP_851820 (OMIM: 300336,300425,300494) neuroligin-3 is (848 aa)
initn: 4480 init1: 4480 opt: 4480 Z-score: 3970.7 bits: 745.7 E(85289): 2e-214
Smith-Waterman score: 5392; 95.2% identity (95.2% similar) in 840 aa overlap (9-808:9-848)
10 20 30 40 50 60
pF1KA1 MWLRLGPPSLSLSPKPTVGRSLCLTLWFLSLALRASTQAPAPTVNTHFGKLRGARVPLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 MWLRLGPPSLSLSPKPTVGRSLCLTLWFLSLALRASTQAPAPTVNTHFGKLRGARVPLPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 EILGPVDQYLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 EILGPVDQYLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLP
70 80 90 100 110 120
130 140 150
pF1KA1 VWFTANLDIVATYIQEPNEDCLYLNVYVPTED----------------------------
::::::::::::::::::::::::::::::::
NP_851 VWFTANLDIVATYIQEPNEDCLYLNVYVPTEDVKRISKECARKPNKKICRKGGSGAKKQG
130 140 150 160 170 180
160 170 180 190 200
pF1KA1 ------------DIRDSGAKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRVG
::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 EDLADNDGDEDEDIRDSGAKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRVG
190 200 210 220 230 240
210 220 230 240 250 260
pF1KA1 VLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 VLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLS
250 260 270 280 290 300
270 280 290 300 310 320
pF1KA1 HHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 HHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKEL
310 320 330 340 350 360
330 340 350 360 370 380
pF1KA1 VEQDIQPARYHVAFGPVIDGDVIPDDPEILMEQGEFLNYDIMLGVNQGEGLKFVEGVVDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 VEQDIQPARYHVAFGPVIDGDVIPDDPEILMEQGEFLNYDIMLGVNQGEGLKFVEGVVDP
370 380 390 400 410 420
390 400 410 420 430 440
pF1KA1 EDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVALFTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 EDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVALFTD
430 440 450 460 470 480
450 460 470 480 490 500
pF1KA1 HQWVEPSVVTADLHARYGSPTYFYAFYHHCQSLMKPAWSDAAHGDEVPYVFGVPMVGPTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 HQWVEPSVVTADLHARYGSPTYFYAFYHHCQSLMKPAWSDAAHGDEVPYVFGVPMVGPTD
490 500 510 520 530 540
510 520 530 540 550 560
pF1KA1 LFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKANRFEEVAWSKYNPRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 LFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKANRFEEVAWSKYNPRD
550 560 570 580 590 600
570 580 590 600 610 620
pF1KA1 QLYLHIGLKPRVRDHYRATKVAFWKHLVPHLYNLHDMFHYTSTTTKVPPPDTTHSSHITR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 QLYLHIGLKPRVRDHYRATKVAFWKHLVPHLYNLHDMFHYTSTTTKVPPPDTTHSSHITR
610 620 630 640 650 660
630 640 650 660 670 680
pF1KA1 RPNGKTWSTKRPAISPAYSNENAQGSWNGDQDAGPLLVENPRDYSTELSVTIAVGASLLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 RPNGKTWSTKRPAISPAYSNENAQGSWNGDQDAGPLLVENPRDYSTELSVTIAVGASLLF
670 680 690 700 710 720
690 700 710 720 730 740
pF1KA1 LNVLAFAALYYRKDKRRQEPLRQPSPQRGAGAPELGAAPEEELAALQLGPTHHECEAGPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 LNVLAFAALYYRKDKRRQEPLRQPSPQRGAGAPELGAAPEEELAALQLGPTHHECEAGPP
730 740 750 760 770 780
750 760 770 780 790 800
pF1KA1 HDTLRLTALPDYTLTLRRSPDDIPLMTPNTITMIPNSLVGLQTLHPYNTFAAGFNSTGLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 HDTLRLTALPDYTLTLRRSPDDIPLMTPNTITMIPNSLVGLQTLHPYNTFAAGFNSTGLP
790 800 810 820 830 840
pF1KA1 HSHSTTRV
::::::::
NP_851 HSHSTTRV
>>XP_016885180 (OMIM: 300427,300495,300497) PREDICTED: n (816 aa)
initn: 3811 init1: 2821 opt: 4138 Z-score: 3668.2 bits: 689.7 E(85289): 1.4e-197
Smith-Waterman score: 4138; 75.1% identity (90.1% similar) in 791 aa overlap (26-808:27-816)
10 20 30 40 50
pF1KA1 MWLRLGPPSLSLSPKPTVGRSLCLTLWFLSLALRAS---TQAPAPTVNTHFGKLRGARV
::. .::.. . .:: :.:::..::.:: :.
XP_016 MSRPQGLLWLPLLFTPVCVMLNSNVLLWLTALAIKFTLIDSQAQYPVVNTNYGKIRGLRT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KA1 PLPSEILGPVDQYLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATHFPPVCPQNI-HTAVP
:::.::::::.::::::::.:: ::.:: ::::: ::.::::.:.: ::::.. . ..
XP_016 PLPNEILGPVEQYLGVPYASPPTGERRFQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KA1 EVMLPVWFTANLDIVATYIQEPNEDCLYLNVYVPTEDDIRDSGAK-PVMVYIHGGSYMEG
. :::.::::::: . ::.:. ::::::::.::::::::.:...: ::::::::::::::
XP_016 HDMLPIWFTANLDTLMTYVQDQNEDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEG
130 140 150 160 170 180
180 190 200 210 220 230
pF1KA1 TGNMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAF
::::::::::::::::::::.:::.:.::::::::::::::::::::::::::. ::..
XP_016 TGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGA
190 200 210 220 230 240
240 250 260 270 280 290
pF1KA1 FGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLL
:::::.:.:.:::: ::::::::::::.::::::.::::::.:::::::::::.::: .:
XP_016 FGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRIL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KA1 ADKVGCNVLDTVDMVDCLRQKSAKELVEQDIQPARYHVAFGPVIDGDVIPDDPEILMEQG
:::::::.:::.:::.:::.:. :::..: : :: ::.:::::::::::::::.::::::
XP_016 ADKVGCNMLDTTDMVECLRNKNYKELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQG
310 320 330 340 350 360
360 370 380 390 400 410
pF1KA1 EFLNYDIMLGVNQGEGLKFVEGVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETI
::::::::::::::::::::.:.:: ::::. .:::.:::::::::::::::::::::::
XP_016 EFLNYDIMLGVNQGEGLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETI
370 380 390 400 410 420
420 430 440 450 460 470
pF1KA1 KFMYTDWADRDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSPTYFYAFYHHCQSLM
:::::::::..::::::::::::::::::: :.:.::::::.:::::::::::::::: :
XP_016 KFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEM
430 440 450 460 470 480
480 490 500 510 520 530
pF1KA1 KPAWSDAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNKPV
::.:.:.:::::::::::.::.:::.:: ::::::::::::::::::::::::::::.::
XP_016 KPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPV
490 500 510 520 530 540
540 550 560 570 580 590
pF1KA1 PQDTKFIHTKANRFEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATKVAFWKHLVPHLYNL
:::::::::: :::::::::::::.::::::::::::::::::::::::: .:::::.::
XP_016 PQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLELVPHLHNL
550 560 570 580 590 600
600 610 620 630 640 650
pF1KA1 HDMFHYTSTTTKVPPPDTTHSSHITRRPNGKTW-STKRPAISPAYSNENAQGSWNGDQDA
...:.:.:::::::::: : . ::: .: : .::::::.:: . .... . .
XP_016 NEIFQYVSTTTKVPPPDMTSFPYGTRRSPAKIWPTTKRPAITPANNPKHSKDPHKTGPED
610 620 630 640 650 660
660 670 680 690 700 710
pF1KA1 GPLLVENPRDYSTELSVTIAVGASLLFLNVLAFAALYYRKDKRRQEPLRQPSPQRGAGAP
.:.:. :::::::::::::::::::::.::::::::.:::::.: :.:::::.. .
XP_016 TTVLIETKRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHETHRRPSPQRNT-TN
670 680 690 700 710
720 730 740 750 760 770
pF1KA1 ELGAAPEEELAALQLGPTHH--ECEAGPPHDTLRLTALPDYTLTLRRSPDDIPLMTPNTI
... .::. .::. .: :::. ::::::: ::::::::::::::::::::::
XP_016 DIAHIQNEEIMSLQMKQLEHDHECESLQAHDTLRLTCPPDYTLTLRRSPDDIPLMTPNTI
720 730 740 750 760 770
780 790 800
pF1KA1 TMIPNSLVGLQTLHPYNTFAAGFNSTGLPHSHSTTRV
:::::.:.:.: :: .:::..: :::.:::.::::::
XP_016 TMIPNTLTGMQPLHTFNTFSGGQNSTNLPHGHSTTRV
780 790 800 810
>>XP_016885182 (OMIM: 300427,300495,300497) PREDICTED: n (816 aa)
initn: 3811 init1: 2821 opt: 4138 Z-score: 3668.2 bits: 689.7 E(85289): 1.4e-197
Smith-Waterman score: 4138; 75.1% identity (90.1% similar) in 791 aa overlap (26-808:27-816)
10 20 30 40 50
pF1KA1 MWLRLGPPSLSLSPKPTVGRSLCLTLWFLSLALRAS---TQAPAPTVNTHFGKLRGARV
::. .::.. . .:: :.:::..::.:: :.
XP_016 MSRPQGLLWLPLLFTPVCVMLNSNVLLWLTALAIKFTLIDSQAQYPVVNTNYGKIRGLRT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KA1 PLPSEILGPVDQYLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATHFPPVCPQNI-HTAVP
:::.::::::.::::::::.:: ::.:: ::::: ::.::::.:.: ::::.. . ..
XP_016 PLPNEILGPVEQYLGVPYASPPTGERRFQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KA1 EVMLPVWFTANLDIVATYIQEPNEDCLYLNVYVPTEDDIRDSGAK-PVMVYIHGGSYMEG
. :::.::::::: . ::.:. ::::::::.::::::::.:...: ::::::::::::::
XP_016 HDMLPIWFTANLDTLMTYVQDQNEDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEG
130 140 150 160 170 180
180 190 200 210 220 230
pF1KA1 TGNMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAF
::::::::::::::::::::.:::.:.::::::::::::::::::::::::::. ::..
XP_016 TGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGA
190 200 210 220 230 240
240 250 260 270 280 290
pF1KA1 FGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLL
:::::.:.:.:::: ::::::::::::.::::::.::::::.:::::::::::.::: .:
XP_016 FGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRIL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KA1 ADKVGCNVLDTVDMVDCLRQKSAKELVEQDIQPARYHVAFGPVIDGDVIPDDPEILMEQG
:::::::.:::.:::.:::.:. :::..: : :: ::.:::::::::::::::.::::::
XP_016 ADKVGCNMLDTTDMVECLRNKNYKELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQG
310 320 330 340 350 360
360 370 380 390 400 410
pF1KA1 EFLNYDIMLGVNQGEGLKFVEGVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETI
::::::::::::::::::::.:.:: ::::. .:::.:::::::::::::::::::::::
XP_016 EFLNYDIMLGVNQGEGLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETI
370 380 390 400 410 420
420 430 440 450 460 470
pF1KA1 KFMYTDWADRDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSPTYFYAFYHHCQSLM
:::::::::..::::::::::::::::::: :.:.::::::.:::::::::::::::: :
XP_016 KFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEM
430 440 450 460 470 480
480 490 500 510 520 530
pF1KA1 KPAWSDAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNKPV
::.:.:.:::::::::::.::.:::.:: ::::::::::::::::::::::::::::.::
XP_016 KPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPV
490 500 510 520 530 540
540 550 560 570 580 590
pF1KA1 PQDTKFIHTKANRFEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATKVAFWKHLVPHLYNL
:::::::::: :::::::::::::.::::::::::::::::::::::::: .:::::.::
XP_016 PQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLELVPHLHNL
550 560 570 580 590 600
600 610 620 630 640 650
pF1KA1 HDMFHYTSTTTKVPPPDTTHSSHITRRPNGKTW-STKRPAISPAYSNENAQGSWNGDQDA
...:.:.:::::::::: : . ::: .: : .::::::.:: . .... . .
XP_016 NEIFQYVSTTTKVPPPDMTSFPYGTRRSPAKIWPTTKRPAITPANNPKHSKDPHKTGPED
610 620 630 640 650 660
660 670 680 690 700 710
pF1KA1 GPLLVENPRDYSTELSVTIAVGASLLFLNVLAFAALYYRKDKRRQEPLRQPSPQRGAGAP
.:.:. :::::::::::::::::::::.::::::::.:::::.: :.:::::.. .
XP_016 TTVLIETKRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHETHRRPSPQRNT-TN
670 680 690 700 710
720 730 740 750 760 770
pF1KA1 ELGAAPEEELAALQLGPTHH--ECEAGPPHDTLRLTALPDYTLTLRRSPDDIPLMTPNTI
... .::. .::. .: :::. ::::::: ::::::::::::::::::::::
XP_016 DIAHIQNEEIMSLQMKQLEHDHECESLQAHDTLRLTCPPDYTLTLRRSPDDIPLMTPNTI
720 730 740 750 760 770
780 790 800
pF1KA1 TMIPNSLVGLQTLHPYNTFAAGFNSTGLPHSHSTTRV
:::::.:.:.: :: .:::..: :::.:::.::::::
XP_016 TMIPNTLTGMQPLHTFNTFSGGQNSTNLPHGHSTTRV
780 790 800 810
>>XP_016885181 (OMIM: 300427,300495,300497) PREDICTED: n (816 aa)
initn: 3811 init1: 2821 opt: 4138 Z-score: 3668.2 bits: 689.7 E(85289): 1.4e-197
Smith-Waterman score: 4138; 75.1% identity (90.1% similar) in 791 aa overlap (26-808:27-816)
10 20 30 40 50
pF1KA1 MWLRLGPPSLSLSPKPTVGRSLCLTLWFLSLALRAS---TQAPAPTVNTHFGKLRGARV
::. .::.. . .:: :.:::..::.:: :.
XP_016 MSRPQGLLWLPLLFTPVCVMLNSNVLLWLTALAIKFTLIDSQAQYPVVNTNYGKIRGLRT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KA1 PLPSEILGPVDQYLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATHFPPVCPQNI-HTAVP
:::.::::::.::::::::.:: ::.:: ::::: ::.::::.:.: ::::.. . ..
XP_016 PLPNEILGPVEQYLGVPYASPPTGERRFQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KA1 EVMLPVWFTANLDIVATYIQEPNEDCLYLNVYVPTEDDIRDSGAK-PVMVYIHGGSYMEG
. :::.::::::: . ::.:. ::::::::.::::::::.:...: ::::::::::::::
XP_016 HDMLPIWFTANLDTLMTYVQDQNEDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEG
130 140 150 160 170 180
180 190 200 210 220 230
pF1KA1 TGNMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAF
::::::::::::::::::::.:::.:.::::::::::::::::::::::::::. ::..
XP_016 TGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGA
190 200 210 220 230 240
240 250 260 270 280 290
pF1KA1 FGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLL
:::::.:.:.:::: ::::::::::::.::::::.::::::.:::::::::::.::: .:
XP_016 FGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRIL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KA1 ADKVGCNVLDTVDMVDCLRQKSAKELVEQDIQPARYHVAFGPVIDGDVIPDDPEILMEQG
:::::::.:::.:::.:::.:. :::..: : :: ::.:::::::::::::::.::::::
XP_016 ADKVGCNMLDTTDMVECLRNKNYKELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQG
310 320 330 340 350 360
360 370 380 390 400 410
pF1KA1 EFLNYDIMLGVNQGEGLKFVEGVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETI
::::::::::::::::::::.:.:: ::::. .:::.:::::::::::::::::::::::
XP_016 EFLNYDIMLGVNQGEGLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETI
370 380 390 400 410 420
420 430 440 450 460 470
pF1KA1 KFMYTDWADRDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSPTYFYAFYHHCQSLM
:::::::::..::::::::::::::::::: :.:.::::::.:::::::::::::::: :
XP_016 KFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEM
430 440 450 460 470 480
480 490 500 510 520 530
pF1KA1 KPAWSDAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNKPV
::.:.:.:::::::::::.::.:::.:: ::::::::::::::::::::::::::::.::
XP_016 KPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPV
490 500 510 520 530 540
540 550 560 570 580 590
pF1KA1 PQDTKFIHTKANRFEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATKVAFWKHLVPHLYNL
:::::::::: :::::::::::::.::::::::::::::::::::::::: .:::::.::
XP_016 PQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLELVPHLHNL
550 560 570 580 590 600
600 610 620 630 640 650
pF1KA1 HDMFHYTSTTTKVPPPDTTHSSHITRRPNGKTW-STKRPAISPAYSNENAQGSWNGDQDA
...:.:.:::::::::: : . ::: .: : .::::::.:: . .... . .
XP_016 NEIFQYVSTTTKVPPPDMTSFPYGTRRSPAKIWPTTKRPAITPANNPKHSKDPHKTGPED
610 620 630 640 650 660
660 670 680 690 700 710
pF1KA1 GPLLVENPRDYSTELSVTIAVGASLLFLNVLAFAALYYRKDKRRQEPLRQPSPQRGAGAP
.:.:. :::::::::::::::::::::.::::::::.:::::.: :.:::::.. .
XP_016 TTVLIETKRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHETHRRPSPQRNT-TN
670 680 690 700 710
720 730 740 750 760 770
pF1KA1 ELGAAPEEELAALQLGPTHH--ECEAGPPHDTLRLTALPDYTLTLRRSPDDIPLMTPNTI
... .::. .::. .: :::. ::::::: ::::::::::::::::::::::
XP_016 DIAHIQNEEIMSLQMKQLEHDHECESLQAHDTLRLTCPPDYTLTLRRSPDDIPLMTPNTI
720 730 740 750 760 770
780 790 800
pF1KA1 TMIPNSLVGLQTLHPYNTFAAGFNSTGLPHSHSTTRV
:::::.:.:.: :: .:::..: :::.:::.::::::
XP_016 TMIPNTLTGMQPLHTFNTFSGGQNSTNLPHGHSTTRV
780 790 800 810
808 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 21:16:55 2016 done: Wed Nov 2 21:16:57 2016
Total Scan time: 10.350 Total Display time: 0.180
Function used was FASTA [36.3.4 Apr, 2011]