FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1520, 766 aa 1>>>pF1KA1520 766 - 766 aa - 766 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3417+/-0.000446; mu= 20.8146+/- 0.028 mean_var=80.1823+/-16.034, 0's: 0 Z-trim(111.5): 299 B-trim: 139 in 1/49 Lambda= 0.143230 statistics sampled from 19855 (20167) to 19855 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.582), E-opt: 0.2 (0.236), width: 16 Scan time: 12.140 The best scores are: opt bits E(85289) XP_011536397 (OMIM: 605453) PREDICTED: ATP-binding ( 766) 4951 1033.5 0 XP_016874592 (OMIM: 605453) PREDICTED: ATP-binding ( 766) 4951 1033.5 0 XP_011536398 (OMIM: 605453) PREDICTED: ATP-binding ( 766) 4951 1033.5 0 NP_062571 (OMIM: 605453) ATP-binding cassette sub- ( 766) 4951 1033.5 0 NP_001229943 (OMIM: 605453) ATP-binding cassette s ( 681) 4398 919.2 0 NP_982269 (OMIM: 605453) ATP-binding cassette sub- ( 683) 4393 918.2 0 XP_005253615 (OMIM: 605453) PREDICTED: ATP-binding ( 548) 3354 703.4 6.5e-202 XP_011536400 (OMIM: 605453) PREDICTED: ATP-binding ( 548) 3354 703.4 6.5e-202 NP_001229942 (OMIM: 605453) ATP-binding cassette s ( 703) 2973 624.7 3.9e-178 NP_062570 (OMIM: 605453) ATP-binding cassette sub- ( 723) 2694 567.1 9.1e-161 NP_000535 (OMIM: 170261,604571) antigen peptide tr ( 703) 1602 341.4 7.5e-93 NP_001276972 (OMIM: 170261,604571) antigen peptide ( 686) 1580 336.9 1.7e-91 XP_016874593 (OMIM: 605453) PREDICTED: ATP-binding ( 485) 1569 334.5 6.4e-91 NP_000584 (OMIM: 170260,604571) antigen peptide tr ( 808) 1537 328.1 9.2e-89 NP_001278951 (OMIM: 170260,604571) antigen peptide ( 547) 1497 319.7 2.1e-86 NP_061313 (OMIM: 170261,604571) antigen peptide tr ( 653) 1491 318.5 5.7e-86 NP_036221 (OMIM: 605454) ATP-binding cassette sub- ( 738) 1380 295.6 5e-79 XP_011536401 (OMIM: 605453) PREDICTED: ATP-binding ( 426) 1376 294.6 5.9e-79 XP_011542437 (OMIM: 605454) PREDICTED: ATP-binding ( 559) 1327 284.5 8.1e-76 NP_001269222 (OMIM: 605464) ATP-binding cassette s ( 630) 1250 268.7 5.4e-71 NP_009119 (OMIM: 605464) ATP-binding cassette sub- ( 718) 1222 262.9 3.3e-69 NP_001269220 (OMIM: 605464) ATP-binding cassette s ( 735) 1222 262.9 3.4e-69 XP_011542438 (OMIM: 605454) PREDICTED: ATP-binding ( 442) 1121 241.9 4.4e-63 NP_000918 (OMIM: 120080,171050,612244) multidrug r (1280) 1082 234.2 2.6e-60 NP_001269221 (OMIM: 605464) ATP-binding cassette s ( 693) 1075 232.5 4.5e-60 NP_061338 (OMIM: 171060,600803,602347,614972) phos (1232) 1075 232.7 7e-60 XP_011514615 (OMIM: 171060,600803,602347,614972) P (1232) 1075 232.7 7e-60 XP_011514614 (OMIM: 171060,600803,602347,614972) P (1247) 1075 232.7 7e-60 XP_011514613 (OMIM: 171060,600803,602347,614972) P (1251) 1075 232.7 7.1e-60 XP_011514612 (OMIM: 171060,600803,602347,614972) P (1259) 1075 232.7 7.1e-60 NP_000434 (OMIM: 171060,600803,602347,614972) phos (1279) 1075 232.8 7.2e-60 NP_061337 (OMIM: 171060,600803,602347,614972) phos (1286) 1075 232.8 7.2e-60 XP_011514611 (OMIM: 171060,600803,602347,614972) P (1287) 1075 232.8 7.2e-60 XP_011514610 (OMIM: 171060,600803,602347,614972) P (1294) 1075 232.8 7.2e-60 XP_016867812 (OMIM: 171060,600803,602347,614972) P (1294) 1075 232.8 7.2e-60 XP_011510382 (OMIM: 601847,603201,605479) PREDICTE ( 936) 1067 231.0 1.8e-59 XP_016860654 (OMIM: 601847,603201,605479) PREDICTE (1314) 1067 231.1 2.3e-59 NP_003733 (OMIM: 601847,603201,605479) bile salt e (1321) 1067 231.1 2.3e-59 XP_006712880 (OMIM: 601847,603201,605479) PREDICTE (1335) 1067 231.1 2.3e-59 XP_011510380 (OMIM: 601847,603201,605479) PREDICTE (1355) 1067 231.1 2.4e-59 XP_011510379 (OMIM: 601847,603201,605479) PREDICTE (1355) 1067 231.1 2.4e-59 XP_011510383 (OMIM: 601847,603201,605479) PREDICTE ( 763) 1062 229.9 3.1e-59 NP_001157413 (OMIM: 611785) ATP-binding cassette s (1257) 1050 227.6 2.5e-58 XP_016860655 (OMIM: 601847,603201,605479) PREDICTE (1098) 958 208.5 1.2e-52 XP_011514617 (OMIM: 171060,600803,602347,614972) P (1074) 927 202.1 1e-50 NP_005680 (OMIM: 111600,605452,609153,614497,61540 ( 842) 803 176.4 4.3e-43 XP_016860656 (OMIM: 601847,603201,605479) PREDICTE ( 916) 764 168.4 1.2e-40 NP_001258626 (OMIM: 300135,301310) ATP-binding cas ( 712) 754 166.2 4.3e-40 NP_001258628 (OMIM: 300135,301310) ATP-binding cas ( 713) 754 166.2 4.3e-40 NP_001258627 (OMIM: 300135,301310) ATP-binding cas ( 726) 754 166.2 4.3e-40 >>XP_011536397 (OMIM: 605453) PREDICTED: ATP-binding cas (766 aa) initn: 4951 init1: 4951 opt: 4951 Z-score: 5527.5 bits: 1033.5 E(85289): 0 Smith-Waterman score: 4951; 100.0% identity (100.0% similar) in 766 aa overlap (1-766:1-766) 10 20 30 40 50 60 pF1KA1 MRLWKAVVVTLAFMSVDICVTTAIYVFSHLDRSLLEDIRHFNIFDSVLDLWAACLYRSCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MRLWKAVVVTLAFMSVDICVTTAIYVFSHLDRSLLEDIRHFNIFDSVLDLWAACLYRSCL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 LLGATIGVAKNSALGPRRLRASWLVITLVCLFVGIYAMVKLLLFSEVRRPIRDPWFWALF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLGATIGVAKNSALGPRRLRASWLVITLVCLFVGIYAMVKLLLFSEVRRPIRDPWFWALF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 VWTYISLGASFLLWWLLSTVRPGTQALEPGAATEAEGFPGSGRPPPEQASGATLQKLLSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VWTYISLGASFLLWWLLSTVRPGTQALEPGAATEAEGFPGSGRPPPEQASGATLQKLLSY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 TKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDGIVIQKSMDQFSTAVVIVCLLAIGSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDGIVIQKSMDQFSTAVVIVCLLAIGSS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 FAAGIRGGIFTLIFARLNIRLRNCLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FAAGIRGGIFTLIFARLNIRLRNCLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 SQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGKYYKRLSKEVQNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGKYYKRLSKEVQNA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 LARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEAAAYMYYVWGSGLTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEAAAYMYYVWGSGLTL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 LVVQVSILYYGGHLVISGQMTSGNLIAFIIYEFVLGDCMESVGSVYSGLMQGVGAAEKVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LVVQVSILYYGGHLVISGQMTSGNLIAFIIYEFVLGDCMESVGSVYSGLMQGVGAAEKVF 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 EFIDRQPTMVHDGSLAPDHLEGRVDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EFIDRQPTMVHDGSLAPDHLEGRVDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 SGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLHRVISLVSQEPVLFARSITDNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLHRVISLVSQEPVLFARSITDNI 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 SYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRN 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 PPVLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAHRLSTVEHAHLIVVLDKGRVVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPVLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAHRLSTVEHAHLIVVLDKGRVVQ 670 680 690 700 710 720 730 740 750 760 pF1KA1 QGTHQQLLAQGGLYAKLVQRQMLGLQPAADFTAGHNEPVANGSHKA :::::::::::::::::::::::::::::::::::::::::::::: XP_011 QGTHQQLLAQGGLYAKLVQRQMLGLQPAADFTAGHNEPVANGSHKA 730 740 750 760 >>XP_016874592 (OMIM: 605453) PREDICTED: ATP-binding cas (766 aa) initn: 4951 init1: 4951 opt: 4951 Z-score: 5527.5 bits: 1033.5 E(85289): 0 Smith-Waterman score: 4951; 100.0% identity (100.0% similar) in 766 aa overlap (1-766:1-766) 10 20 30 40 50 60 pF1KA1 MRLWKAVVVTLAFMSVDICVTTAIYVFSHLDRSLLEDIRHFNIFDSVLDLWAACLYRSCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MRLWKAVVVTLAFMSVDICVTTAIYVFSHLDRSLLEDIRHFNIFDSVLDLWAACLYRSCL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 LLGATIGVAKNSALGPRRLRASWLVITLVCLFVGIYAMVKLLLFSEVRRPIRDPWFWALF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLGATIGVAKNSALGPRRLRASWLVITLVCLFVGIYAMVKLLLFSEVRRPIRDPWFWALF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 VWTYISLGASFLLWWLLSTVRPGTQALEPGAATEAEGFPGSGRPPPEQASGATLQKLLSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VWTYISLGASFLLWWLLSTVRPGTQALEPGAATEAEGFPGSGRPPPEQASGATLQKLLSY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 TKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDGIVIQKSMDQFSTAVVIVCLLAIGSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDGIVIQKSMDQFSTAVVIVCLLAIGSS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 FAAGIRGGIFTLIFARLNIRLRNCLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FAAGIRGGIFTLIFARLNIRLRNCLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 SQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGKYYKRLSKEVQNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGKYYKRLSKEVQNA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 LARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEAAAYMYYVWGSGLTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEAAAYMYYVWGSGLTL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 LVVQVSILYYGGHLVISGQMTSGNLIAFIIYEFVLGDCMESVGSVYSGLMQGVGAAEKVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LVVQVSILYYGGHLVISGQMTSGNLIAFIIYEFVLGDCMESVGSVYSGLMQGVGAAEKVF 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 EFIDRQPTMVHDGSLAPDHLEGRVDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EFIDRQPTMVHDGSLAPDHLEGRVDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 SGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLHRVISLVSQEPVLFARSITDNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLHRVISLVSQEPVLFARSITDNI 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 SYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRN 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 PPVLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAHRLSTVEHAHLIVVLDKGRVVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPVLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAHRLSTVEHAHLIVVLDKGRVVQ 670 680 690 700 710 720 730 740 750 760 pF1KA1 QGTHQQLLAQGGLYAKLVQRQMLGLQPAADFTAGHNEPVANGSHKA :::::::::::::::::::::::::::::::::::::::::::::: XP_016 QGTHQQLLAQGGLYAKLVQRQMLGLQPAADFTAGHNEPVANGSHKA 730 740 750 760 >>XP_011536398 (OMIM: 605453) PREDICTED: ATP-binding cas (766 aa) initn: 4951 init1: 4951 opt: 4951 Z-score: 5527.5 bits: 1033.5 E(85289): 0 Smith-Waterman score: 4951; 100.0% identity (100.0% similar) in 766 aa overlap (1-766:1-766) 10 20 30 40 50 60 pF1KA1 MRLWKAVVVTLAFMSVDICVTTAIYVFSHLDRSLLEDIRHFNIFDSVLDLWAACLYRSCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MRLWKAVVVTLAFMSVDICVTTAIYVFSHLDRSLLEDIRHFNIFDSVLDLWAACLYRSCL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 LLGATIGVAKNSALGPRRLRASWLVITLVCLFVGIYAMVKLLLFSEVRRPIRDPWFWALF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLGATIGVAKNSALGPRRLRASWLVITLVCLFVGIYAMVKLLLFSEVRRPIRDPWFWALF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 VWTYISLGASFLLWWLLSTVRPGTQALEPGAATEAEGFPGSGRPPPEQASGATLQKLLSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VWTYISLGASFLLWWLLSTVRPGTQALEPGAATEAEGFPGSGRPPPEQASGATLQKLLSY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 TKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDGIVIQKSMDQFSTAVVIVCLLAIGSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDGIVIQKSMDQFSTAVVIVCLLAIGSS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 FAAGIRGGIFTLIFARLNIRLRNCLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FAAGIRGGIFTLIFARLNIRLRNCLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 SQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGKYYKRLSKEVQNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGKYYKRLSKEVQNA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 LARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEAAAYMYYVWGSGLTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEAAAYMYYVWGSGLTL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 LVVQVSILYYGGHLVISGQMTSGNLIAFIIYEFVLGDCMESVGSVYSGLMQGVGAAEKVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LVVQVSILYYGGHLVISGQMTSGNLIAFIIYEFVLGDCMESVGSVYSGLMQGVGAAEKVF 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 EFIDRQPTMVHDGSLAPDHLEGRVDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EFIDRQPTMVHDGSLAPDHLEGRVDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 SGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLHRVISLVSQEPVLFARSITDNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLHRVISLVSQEPVLFARSITDNI 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 SYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRN 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 PPVLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAHRLSTVEHAHLIVVLDKGRVVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPVLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAHRLSTVEHAHLIVVLDKGRVVQ 670 680 690 700 710 720 730 740 750 760 pF1KA1 QGTHQQLLAQGGLYAKLVQRQMLGLQPAADFTAGHNEPVANGSHKA :::::::::::::::::::::::::::::::::::::::::::::: XP_011 QGTHQQLLAQGGLYAKLVQRQMLGLQPAADFTAGHNEPVANGSHKA 730 740 750 760 >>NP_062571 (OMIM: 605453) ATP-binding cassette sub-fami (766 aa) initn: 4951 init1: 4951 opt: 4951 Z-score: 5527.5 bits: 1033.5 E(85289): 0 Smith-Waterman score: 4951; 100.0% identity (100.0% similar) in 766 aa overlap (1-766:1-766) 10 20 30 40 50 60 pF1KA1 MRLWKAVVVTLAFMSVDICVTTAIYVFSHLDRSLLEDIRHFNIFDSVLDLWAACLYRSCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 MRLWKAVVVTLAFMSVDICVTTAIYVFSHLDRSLLEDIRHFNIFDSVLDLWAACLYRSCL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 LLGATIGVAKNSALGPRRLRASWLVITLVCLFVGIYAMVKLLLFSEVRRPIRDPWFWALF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 LLGATIGVAKNSALGPRRLRASWLVITLVCLFVGIYAMVKLLLFSEVRRPIRDPWFWALF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 VWTYISLGASFLLWWLLSTVRPGTQALEPGAATEAEGFPGSGRPPPEQASGATLQKLLSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 VWTYISLGASFLLWWLLSTVRPGTQALEPGAATEAEGFPGSGRPPPEQASGATLQKLLSY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 TKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDGIVIQKSMDQFSTAVVIVCLLAIGSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 TKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDGIVIQKSMDQFSTAVVIVCLLAIGSS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 FAAGIRGGIFTLIFARLNIRLRNCLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 FAAGIRGGIFTLIFARLNIRLRNCLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 SQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGKYYKRLSKEVQNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 SQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGKYYKRLSKEVQNA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 LARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEAAAYMYYVWGSGLTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 LARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEAAAYMYYVWGSGLTL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 LVVQVSILYYGGHLVISGQMTSGNLIAFIIYEFVLGDCMESVGSVYSGLMQGVGAAEKVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 LVVQVSILYYGGHLVISGQMTSGNLIAFIIYEFVLGDCMESVGSVYSGLMQGVGAAEKVF 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 EFIDRQPTMVHDGSLAPDHLEGRVDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 EFIDRQPTMVHDGSLAPDHLEGRVDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 SGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLHRVISLVSQEPVLFARSITDNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 SGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLHRVISLVSQEPVLFARSITDNI 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 SYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 SYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRN 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 PPVLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAHRLSTVEHAHLIVVLDKGRVVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 PPVLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAHRLSTVEHAHLIVVLDKGRVVQ 670 680 690 700 710 720 730 740 750 760 pF1KA1 QGTHQQLLAQGGLYAKLVQRQMLGLQPAADFTAGHNEPVANGSHKA :::::::::::::::::::::::::::::::::::::::::::::: NP_062 QGTHQQLLAQGGLYAKLVQRQMLGLQPAADFTAGHNEPVANGSHKA 730 740 750 760 >>NP_001229943 (OMIM: 605453) ATP-binding cassette sub-f (681 aa) initn: 4398 init1: 4398 opt: 4398 Z-score: 4910.6 bits: 919.2 E(85289): 0 Smith-Waterman score: 4398; 100.0% identity (100.0% similar) in 681 aa overlap (1-681:1-681) 10 20 30 40 50 60 pF1KA1 MRLWKAVVVTLAFMSVDICVTTAIYVFSHLDRSLLEDIRHFNIFDSVLDLWAACLYRSCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MRLWKAVVVTLAFMSVDICVTTAIYVFSHLDRSLLEDIRHFNIFDSVLDLWAACLYRSCL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 LLGATIGVAKNSALGPRRLRASWLVITLVCLFVGIYAMVKLLLFSEVRRPIRDPWFWALF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLGATIGVAKNSALGPRRLRASWLVITLVCLFVGIYAMVKLLLFSEVRRPIRDPWFWALF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 VWTYISLGASFLLWWLLSTVRPGTQALEPGAATEAEGFPGSGRPPPEQASGATLQKLLSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VWTYISLGASFLLWWLLSTVRPGTQALEPGAATEAEGFPGSGRPPPEQASGATLQKLLSY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 TKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDGIVIQKSMDQFSTAVVIVCLLAIGSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDGIVIQKSMDQFSTAVVIVCLLAIGSS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 FAAGIRGGIFTLIFARLNIRLRNCLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FAAGIRGGIFTLIFARLNIRLRNCLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 SQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGKYYKRLSKEVQNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGKYYKRLSKEVQNA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 LARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEAAAYMYYVWGSGLTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEAAAYMYYVWGSGLTL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 LVVQVSILYYGGHLVISGQMTSGNLIAFIIYEFVLGDCMESVGSVYSGLMQGVGAAEKVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LVVQVSILYYGGHLVISGQMTSGNLIAFIIYEFVLGDCMESVGSVYSGLMQGVGAAEKVF 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 EFIDRQPTMVHDGSLAPDHLEGRVDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EFIDRQPTMVHDGSLAPDHLEGRVDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 SGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLHRVISLVSQEPVLFARSITDNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLHRVISLVSQEPVLFARSITDNI 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 SYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRN 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 PPVLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAHRLSTVEHAHLIVVLDKGRVVQ ::::::::::::::::::::: NP_001 PPVLILDEATSALDAESEYLI 670 680 >>NP_982269 (OMIM: 605453) ATP-binding cassette sub-fami (683 aa) initn: 4393 init1: 4393 opt: 4393 Z-score: 4905.0 bits: 918.2 E(85289): 0 Smith-Waterman score: 4393; 100.0% identity (100.0% similar) in 680 aa overlap (1-680:1-680) 10 20 30 40 50 60 pF1KA1 MRLWKAVVVTLAFMSVDICVTTAIYVFSHLDRSLLEDIRHFNIFDSVLDLWAACLYRSCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_982 MRLWKAVVVTLAFMSVDICVTTAIYVFSHLDRSLLEDIRHFNIFDSVLDLWAACLYRSCL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 LLGATIGVAKNSALGPRRLRASWLVITLVCLFVGIYAMVKLLLFSEVRRPIRDPWFWALF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_982 LLGATIGVAKNSALGPRRLRASWLVITLVCLFVGIYAMVKLLLFSEVRRPIRDPWFWALF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 VWTYISLGASFLLWWLLSTVRPGTQALEPGAATEAEGFPGSGRPPPEQASGATLQKLLSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_982 VWTYISLGASFLLWWLLSTVRPGTQALEPGAATEAEGFPGSGRPPPEQASGATLQKLLSY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 TKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDGIVIQKSMDQFSTAVVIVCLLAIGSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_982 TKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDGIVIQKSMDQFSTAVVIVCLLAIGSS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 FAAGIRGGIFTLIFARLNIRLRNCLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_982 FAAGIRGGIFTLIFARLNIRLRNCLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 SQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGKYYKRLSKEVQNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_982 SQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGKYYKRLSKEVQNA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 LARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEAAAYMYYVWGSGLTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_982 LARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEAAAYMYYVWGSGLTL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 LVVQVSILYYGGHLVISGQMTSGNLIAFIIYEFVLGDCMESVGSVYSGLMQGVGAAEKVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_982 LVVQVSILYYGGHLVISGQMTSGNLIAFIIYEFVLGDCMESVGSVYSGLMQGVGAAEKVF 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 EFIDRQPTMVHDGSLAPDHLEGRVDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_982 EFIDRQPTMVHDGSLAPDHLEGRVDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 SGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLHRVISLVSQEPVLFARSITDNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_982 SGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLHRVISLVSQEPVLFARSITDNI 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 SYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_982 SYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRN 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 PPVLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAHRLSTVEHAHLIVVLDKGRVVQ :::::::::::::::::::: NP_982 PPVLILDEATSALDAESEYLCAG 670 680 >>XP_005253615 (OMIM: 605453) PREDICTED: ATP-binding cas (548 aa) initn: 3354 init1: 3354 opt: 3354 Z-score: 3746.0 bits: 703.4 E(85289): 6.5e-202 Smith-Waterman score: 3354; 100.0% identity (100.0% similar) in 524 aa overlap (243-766:25-548) 220 230 240 250 260 270 pF1KA1 IDGIVIQKSMDQFSTAVVIVCLLAIGSSFAAGIRGGIFTLIFARLNIRLRNCLFRSLVSQ :::::::::::::::::::::::::::::: XP_005 MASSSRKAWISSARLSSSCACWPLAGIRGGIFTLIFARLNIRLRNCLFRSLVSQ 10 20 30 40 50 280 290 300 310 320 330 pF1KA1 ETSFFDENRTGDLISRLTSDTTMVSDLVSQNINVFLRNTVKVTGVVVFMFSLSWQLSLVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ETSFFDENRTGDLISRLTSDTTMVSDLVSQNINVFLRNTVKVTGVVVFMFSLSWQLSLVT 60 70 80 90 100 110 340 350 360 370 380 390 pF1KA1 FMGFPIIMMVSNIYGKYYKRLSKEVQNALARASNTAEETISAMKTVRSFANEEEEAEVYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FMGFPIIMMVSNIYGKYYKRLSKEVQNALARASNTAEETISAMKTVRSFANEEEEAEVYL 120 130 140 150 160 170 400 410 420 430 440 450 pF1KA1 RKLQQVYKLNRKEAAAYMYYVWGSGLTLLVVQVSILYYGGHLVISGQMTSGNLIAFIIYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RKLQQVYKLNRKEAAAYMYYVWGSGLTLLVVQVSILYYGGHLVISGQMTSGNLIAFIIYE 180 190 200 210 220 230 460 470 480 490 500 510 pF1KA1 FVLGDCMESVGSVYSGLMQGVGAAEKVFEFIDRQPTMVHDGSLAPDHLEGRVDFENVTFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FVLGDCMESVGSVYSGLMQGVGAAEKVFEFIDRQPTMVHDGSLAPDHLEGRVDFENVTFT 240 250 260 270 280 290 520 530 540 550 560 570 pF1KA1 YRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLEGGRVLLDGKPISA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLEGGRVLLDGKPISA 300 310 320 330 340 350 580 590 600 610 620 630 pF1KA1 YDHKYLHRVISLVSQEPVLFARSITDNISYGLPTVPFEMVVEAAQKANAHGFIMELQDGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YDHKYLHRVISLVSQEPVLFARSITDNISYGLPTVPFEMVVEAAQKANAHGFIMELQDGY 360 370 380 390 400 410 640 650 660 670 680 690 pF1KA1 STETGEKGAQLSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAIHGNLQKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 STETGEKGAQLSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAIHGNLQKH 420 430 440 450 460 470 700 710 720 730 740 750 pF1KA1 TVLIIAHRLSTVEHAHLIVVLDKGRVVQQGTHQQLLAQGGLYAKLVQRQMLGLQPAADFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TVLIIAHRLSTVEHAHLIVVLDKGRVVQQGTHQQLLAQGGLYAKLVQRQMLGLQPAADFT 480 490 500 510 520 530 760 pF1KA1 AGHNEPVANGSHKA :::::::::::::: XP_005 AGHNEPVANGSHKA 540 >>XP_011536400 (OMIM: 605453) PREDICTED: ATP-binding cas (548 aa) initn: 3354 init1: 3354 opt: 3354 Z-score: 3746.0 bits: 703.4 E(85289): 6.5e-202 Smith-Waterman score: 3354; 100.0% identity (100.0% similar) in 524 aa overlap (243-766:25-548) 220 230 240 250 260 270 pF1KA1 IDGIVIQKSMDQFSTAVVIVCLLAIGSSFAAGIRGGIFTLIFARLNIRLRNCLFRSLVSQ :::::::::::::::::::::::::::::: XP_011 MASSSRKAWISSARLSSSCACWPLAGIRGGIFTLIFARLNIRLRNCLFRSLVSQ 10 20 30 40 50 280 290 300 310 320 330 pF1KA1 ETSFFDENRTGDLISRLTSDTTMVSDLVSQNINVFLRNTVKVTGVVVFMFSLSWQLSLVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ETSFFDENRTGDLISRLTSDTTMVSDLVSQNINVFLRNTVKVTGVVVFMFSLSWQLSLVT 60 70 80 90 100 110 340 350 360 370 380 390 pF1KA1 FMGFPIIMMVSNIYGKYYKRLSKEVQNALARASNTAEETISAMKTVRSFANEEEEAEVYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FMGFPIIMMVSNIYGKYYKRLSKEVQNALARASNTAEETISAMKTVRSFANEEEEAEVYL 120 130 140 150 160 170 400 410 420 430 440 450 pF1KA1 RKLQQVYKLNRKEAAAYMYYVWGSGLTLLVVQVSILYYGGHLVISGQMTSGNLIAFIIYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RKLQQVYKLNRKEAAAYMYYVWGSGLTLLVVQVSILYYGGHLVISGQMTSGNLIAFIIYE 180 190 200 210 220 230 460 470 480 490 500 510 pF1KA1 FVLGDCMESVGSVYSGLMQGVGAAEKVFEFIDRQPTMVHDGSLAPDHLEGRVDFENVTFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FVLGDCMESVGSVYSGLMQGVGAAEKVFEFIDRQPTMVHDGSLAPDHLEGRVDFENVTFT 240 250 260 270 280 290 520 530 540 550 560 570 pF1KA1 YRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLEGGRVLLDGKPISA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLEGGRVLLDGKPISA 300 310 320 330 340 350 580 590 600 610 620 630 pF1KA1 YDHKYLHRVISLVSQEPVLFARSITDNISYGLPTVPFEMVVEAAQKANAHGFIMELQDGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YDHKYLHRVISLVSQEPVLFARSITDNISYGLPTVPFEMVVEAAQKANAHGFIMELQDGY 360 370 380 390 400 410 640 650 660 670 680 690 pF1KA1 STETGEKGAQLSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAIHGNLQKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STETGEKGAQLSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAIHGNLQKH 420 430 440 450 460 470 700 710 720 730 740 750 pF1KA1 TVLIIAHRLSTVEHAHLIVVLDKGRVVQQGTHQQLLAQGGLYAKLVQRQMLGLQPAADFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TVLIIAHRLSTVEHAHLIVVLDKGRVVQQGTHQQLLAQGGLYAKLVQRQMLGLQPAADFT 480 490 500 510 520 530 760 pF1KA1 AGHNEPVANGSHKA :::::::::::::: XP_011 AGHNEPVANGSHKA 540 >>NP_001229942 (OMIM: 605453) ATP-binding cassette sub-f (703 aa) initn: 2973 init1: 2973 opt: 2973 Z-score: 3319.0 bits: 624.7 E(85289): 3.9e-178 Smith-Waterman score: 4395; 91.8% identity (91.8% similar) in 766 aa overlap (1-766:1-703) 10 20 30 40 50 60 pF1KA1 MRLWKAVVVTLAFMSVDICVTTAIYVFSHLDRSLLEDIRHFNIFDSVLDLWAACLYRSCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MRLWKAVVVTLAFMSVDICVTTAIYVFSHLDRSLLEDIRHFNIFDSVLDLWAACLYRSCL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 LLGATIGVAKNSALGPRRLRASWLVITLVCLFVGIYAMVKLLLFSEVRRPIRDPWFWALF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLGATIGVAKNSALGPRRLRASWLVITLVCLFVGIYAMVKLLLFSEVRRPIRDPWFWALF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 VWTYISLGASFLLWWLLSTVRPGTQALEPGAATEAEGFPGSGRPPPEQASGATLQKLLSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VWTYISLGASFLLWWLLSTVRPGTQALEPGAATEAEGFPGSGRPPPEQASGATLQKLLSY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 TKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDGIVIQKSMDQFSTAVVIVCLLAIGSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDGIVIQKSMDQFSTAVVIVCLLAIGSS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 FAAGIRGGIFTLIFARLNIRLRNCLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FAAGIRGGIFTLIFARLNIRLRNCLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 SQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGKYYKRLSKEVQNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGKYYKRLSKEVQNA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 LARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEAAAYMYYVWGSGLTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEAAAYMYYVWGSGLTL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 LVVQVSILYYGGHLVISGQMTSGNLIAFIIYEFVLGDCMESVGSVYSGLMQGVGAAEKVF :::::::::::::::::::::::::::::::::::::::: NP_001 LVVQVSILYYGGHLVISGQMTSGNLIAFIIYEFVLGDCME-------------------- 430 440 450 460 490 500 510 520 530 540 pF1KA1 EFIDRQPTMVHDGSLAPDHLEGRVDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGP ::::::::::::::::: NP_001 -------------------------------------------NVSFSLSPGKVTALVGP 470 550 560 570 580 590 600 pF1KA1 SGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLHRVISLVSQEPVLFARSITDNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLHRVISLVSQEPVLFARSITDNI 480 490 500 510 520 530 610 620 630 640 650 660 pF1KA1 SYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRN 540 550 560 570 580 590 670 680 690 700 710 720 pF1KA1 PPVLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAHRLSTVEHAHLIVVLDKGRVVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPVLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAHRLSTVEHAHLIVVLDKGRVVQ 600 610 620 630 640 650 730 740 750 760 pF1KA1 QGTHQQLLAQGGLYAKLVQRQMLGLQPAADFTAGHNEPVANGSHKA :::::::::::::::::::::::::::::::::::::::::::::: NP_001 QGTHQQLLAQGGLYAKLVQRQMLGLQPAADFTAGHNEPVANGSHKA 660 670 680 690 700 >>NP_062570 (OMIM: 605453) ATP-binding cassette sub-fami (723 aa) initn: 4664 init1: 2694 opt: 2694 Z-score: 3007.3 bits: 567.1 E(85289): 9.1e-161 Smith-Waterman score: 4582; 94.4% identity (94.4% similar) in 766 aa overlap (1-766:1-723) 10 20 30 40 50 60 pF1KA1 MRLWKAVVVTLAFMSVDICVTTAIYVFSHLDRSLLEDIRHFNIFDSVLDLWAACLYRSCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 MRLWKAVVVTLAFMSVDICVTTAIYVFSHLDRSLLEDIRHFNIFDSVLDLWAACLYRSCL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 LLGATIGVAKNSALGPRRLRASWLVITLVCLFVGIYAMVKLLLFSEVRRPIRDPWFWALF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 LLGATIGVAKNSALGPRRLRASWLVITLVCLFVGIYAMVKLLLFSEVRRPIRDPWFWALF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 VWTYISLGASFLLWWLLSTVRPGTQALEPGAATEAEGFPGSGRPPPEQASGATLQKLLSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 VWTYISLGASFLLWWLLSTVRPGTQALEPGAATEAEGFPGSGRPPPEQASGATLQKLLSY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 TKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDGIVIQKSMDQFSTAVVIVCLLAIGSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 TKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDGIVIQKSMDQFSTAVVIVCLLAIGSS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 FAAGIRGGIFTLIFARLNIRLRNCLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 FAAGIRGGIFTLIFARLNIRLRNCLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 SQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGKYYKRLSKEVQNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 SQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGKYYKRLSKEVQNA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 LARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEAAAYMYYVWGSGLTL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 LARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEAAAYMYYVWGSG--- 370 380 390 400 410 430 440 450 460 470 480 pF1KA1 LVVQVSILYYGGHLVISGQMTSGNLIAFIIYEFVLGDCMESVGSVYSGLMQGVGAAEKVF :::::::::::::::::::: NP_062 ----------------------------------------SVGSVYSGLMQGVGAAEKVF 420 430 490 500 510 520 530 540 pF1KA1 EFIDRQPTMVHDGSLAPDHLEGRVDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 EFIDRQPTMVHDGSLAPDHLEGRVDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGP 440 450 460 470 480 490 550 560 570 580 590 600 pF1KA1 SGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLHRVISLVSQEPVLFARSITDNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 SGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLHRVISLVSQEPVLFARSITDNI 500 510 520 530 540 550 610 620 630 640 650 660 pF1KA1 SYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 SYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRN 560 570 580 590 600 610 670 680 690 700 710 720 pF1KA1 PPVLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAHRLSTVEHAHLIVVLDKGRVVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 PPVLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAHRLSTVEHAHLIVVLDKGRVVQ 620 630 640 650 660 670 730 740 750 760 pF1KA1 QGTHQQLLAQGGLYAKLVQRQMLGLQPAADFTAGHNEPVANGSHKA :::::::::::::::::::::::::::::::::::::::::::::: NP_062 QGTHQQLLAQGGLYAKLVQRQMLGLQPAADFTAGHNEPVANGSHKA 680 690 700 710 720 766 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 11:14:54 2016 done: Thu Nov 3 11:14:56 2016 Total Scan time: 12.140 Total Display time: 0.230 Function used was FASTA [36.3.4 Apr, 2011]