FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1525, 1132 aa 1>>>pF1KA1525 1132 - 1132 aa - 1132 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.1980+/-0.000439; mu= -4.8534+/- 0.028 mean_var=332.4496+/-70.825, 0's: 0 Z-trim(119.8): 12 B-trim: 50 in 1/57 Lambda= 0.070341 statistics sampled from 34277 (34289) to 34277 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.714), E-opt: 0.2 (0.402), width: 16 Scan time: 18.710 The best scores are: opt bits E(85289) NP_001002860 (OMIM: 610386) BTB/POZ domain-contain (1132) 7577 783.9 0 XP_011535241 (OMIM: 610386) PREDICTED: BTB/POZ dom (1132) 7577 783.9 0 NP_001276062 (OMIM: 610386) BTB/POZ domain-contain ( 781) 5031 525.4 5.3e-148 XP_016876927 (OMIM: 610386) PREDICTED: BTB/POZ dom ( 657) 4438 465.1 6e-130 NP_060637 (OMIM: 610386) BTB/POZ domain-containing ( 410) 2548 273.2 2.3e-72 >>NP_001002860 (OMIM: 610386) BTB/POZ domain-containing (1132 aa) initn: 7577 init1: 7577 opt: 7577 Z-score: 4172.2 bits: 783.9 E(85289): 0 Smith-Waterman score: 7577; 100.0% identity (100.0% similar) in 1132 aa overlap (1-1132:1-1132) 10 20 30 40 50 60 pF1KA1 MGANASNYPHSCSPRVGGNSQAQQTFIGTSSYSQQGYGCESKLYSLDHGHEKPQDKKKRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGANASNYPHSCSPRVGGNSQAQQTFIGTSSYSQQGYGCESKLYSLDHGHEKPQDKKKRT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 SGLATLKKKFIKRRKSNRSADHAKQMRELLSGWDVRDVNALVEEYEGTSALKELSLQASL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGLATLKKKFIKRRKSNRSADHAKQMRELLSGWDVRDVNALVEEYEGTSALKELSLQASL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 ARPEARTLQKDMADLYEYKYCTDVDLIFQETCFPVHRAILAARCPFFKTLLSSSPEYGAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ARPEARTLQKDMADLYEYKYCTDVDLIFQETCFPVHRAILAARCPFFKTLLSSSPEYGAE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 IIMDINTAGIDMPMFSALLHYLYTGEFGMEDSRFQNVDILVQLSEEFGTPNSLDVDMRGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IIMDINTAGIDMPMFSALLHYLYTGEFGMEDSRFQNVDILVQLSEEFGTPNSLDVDMRGL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 FDYMCYYDVVLSFSSDSELVEAFGGNQNCLDEELKAHKAVISARSPFFRNLLQRRIRTGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FDYMCYYDVVLSFSSDSELVEAFGGNQNCLDEELKAHKAVISARSPFFRNLLQRRIRTGE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 EITDRTLRTPTRIILDESIIPKKYATVILHCMYTDVVDLSVLHCSPSVGSLSEVQALVAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EITDRTLRTPTRIILDESIIPKKYATVILHCMYTDVVDLSVLHCSPSVGSLSEVQALVAG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 KPNMTRAEEAMELYHIALFLEFNMLAQGCEDIIAESISLDTLIAILKWSSHPYGSKWVHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPNMTRAEEAMELYHIALFLEFNMLAQGCEDIIAESISLDTLIAILKWSSHPYGSKWVHR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 QALHFLCEEFSQVMTSDVFYELSKDHLLTAIQSDYLQASEQDILKYLIKWGEHQLMKRIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QALHFLCEEFSQVMTSDVFYELSKDHLLTAIQSDYLQASEQDILKYLIKWGEHQLMKRIA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 DREPNLLSGTAHSVNKRGVKRRDLDMEELREILSSLLPFVRIEHILPINSEVLSDAMKRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DREPNLLSGTAHSVNKRGVKRRDLDMEELREILSSLLPFVRIEHILPINSEVLSDAMKRG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 LISTPPSDMLPTTEGGKSNAWLRQKNAGIYVRPRLFSPYVEEAKSVLDEMMVEQTDLVRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LISTPPSDMLPTTEGGKSNAWLRQKNAGIYVRPRLFSPYVEEAKSVLDEMMVEQTDLVRL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 RMVRMSNVPDTLYMVNNAVPQCCHMISHQQISSNQSSPPSVVANEIPVPRLLIMKDMVRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RMVRMSNVPDTLYMVNNAVPQCCHMISHQQISSNQSSPPSVVANEIPVPRLLIMKDMVRR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 LQELRHTEQVQRAYALNCGEGATVSYEIQIRVLREFGLADAAAELLQNPHKFFPDERFGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQELRHTEQVQRAYALNCGEGATVSYEIQIRVLREFGLADAAAELLQNPHKFFPDERFGD 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 ESPLLTMRQPGRCRVNSTPPAETMFTDLDSFVAFHPPLPPPPPPYHPPATPIHNQLKAGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ESPLLTMRQPGRCRVNSTPPAETMFTDLDSFVAFHPPLPPPPPPYHPPATPIHNQLKAGW 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 KQRPPSQHPSRSFSYPCNHSLFHSRTAPKAGPPPVYLPSVKAAPPDCTSTAGLGRQTVAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KQRPPSQHPSRSFSYPCNHSLFHSRTAPKAGPPPVYLPSVKAAPPDCTSTAGLGRQTVAA 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 AAATTTSTATAAAAAASEKQVRTQPVLNDLMPDIAVGVSTLSLKDRRLPELAVDTELSQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AAATTTSTATAAAAAASEKQVRTQPVLNDLMPDIAVGVSTLSLKDRRLPELAVDTELSQS 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 VSEAGPGPPQHLSCIPQRHTHTSRKKHTLEQKTDTRENPQEYPDFYDFSNAACRPSTPAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VSEAGPGPPQHLSCIPQRHTHTSRKKHTLEQKTDTRENPQEYPDFYDFSNAACRPSTPAL 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 SRRTPSPSQGGYFGPDLYSHNKASPSGLKSAYLPGQTSPKKQEEARREYPLSPDGHLHRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SRRTPSPSQGGYFGPDLYSHNKASPSGLKSAYLPGQTSPKKQEEARREYPLSPDGHLHRQ 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA1 KNEPIHLDVVEQPPQRSDFPLAAPENASTGPAHVRGRTAVETDLTFGLTPNRPSLSACSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KNEPIHLDVVEQPPQRSDFPLAAPENASTGPAHVRGRTAVETDLTFGLTPNRPSLSACSS 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 pF1KA1 EAPEERSGRRLADSESLGHGAQRNTDLEREDSISRGRRSPSKPDFLYKKSAL :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EAPEERSGRRLADSESLGHGAQRNTDLEREDSISRGRRSPSKPDFLYKKSAL 1090 1100 1110 1120 1130 >>XP_011535241 (OMIM: 610386) PREDICTED: BTB/POZ domain- (1132 aa) initn: 7577 init1: 7577 opt: 7577 Z-score: 4172.2 bits: 783.9 E(85289): 0 Smith-Waterman score: 7577; 100.0% identity (100.0% similar) in 1132 aa overlap (1-1132:1-1132) 10 20 30 40 50 60 pF1KA1 MGANASNYPHSCSPRVGGNSQAQQTFIGTSSYSQQGYGCESKLYSLDHGHEKPQDKKKRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MGANASNYPHSCSPRVGGNSQAQQTFIGTSSYSQQGYGCESKLYSLDHGHEKPQDKKKRT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 SGLATLKKKFIKRRKSNRSADHAKQMRELLSGWDVRDVNALVEEYEGTSALKELSLQASL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGLATLKKKFIKRRKSNRSADHAKQMRELLSGWDVRDVNALVEEYEGTSALKELSLQASL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 ARPEARTLQKDMADLYEYKYCTDVDLIFQETCFPVHRAILAARCPFFKTLLSSSPEYGAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ARPEARTLQKDMADLYEYKYCTDVDLIFQETCFPVHRAILAARCPFFKTLLSSSPEYGAE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 IIMDINTAGIDMPMFSALLHYLYTGEFGMEDSRFQNVDILVQLSEEFGTPNSLDVDMRGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IIMDINTAGIDMPMFSALLHYLYTGEFGMEDSRFQNVDILVQLSEEFGTPNSLDVDMRGL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 FDYMCYYDVVLSFSSDSELVEAFGGNQNCLDEELKAHKAVISARSPFFRNLLQRRIRTGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FDYMCYYDVVLSFSSDSELVEAFGGNQNCLDEELKAHKAVISARSPFFRNLLQRRIRTGE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 EITDRTLRTPTRIILDESIIPKKYATVILHCMYTDVVDLSVLHCSPSVGSLSEVQALVAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EITDRTLRTPTRIILDESIIPKKYATVILHCMYTDVVDLSVLHCSPSVGSLSEVQALVAG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 KPNMTRAEEAMELYHIALFLEFNMLAQGCEDIIAESISLDTLIAILKWSSHPYGSKWVHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KPNMTRAEEAMELYHIALFLEFNMLAQGCEDIIAESISLDTLIAILKWSSHPYGSKWVHR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 QALHFLCEEFSQVMTSDVFYELSKDHLLTAIQSDYLQASEQDILKYLIKWGEHQLMKRIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QALHFLCEEFSQVMTSDVFYELSKDHLLTAIQSDYLQASEQDILKYLIKWGEHQLMKRIA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 DREPNLLSGTAHSVNKRGVKRRDLDMEELREILSSLLPFVRIEHILPINSEVLSDAMKRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DREPNLLSGTAHSVNKRGVKRRDLDMEELREILSSLLPFVRIEHILPINSEVLSDAMKRG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 LISTPPSDMLPTTEGGKSNAWLRQKNAGIYVRPRLFSPYVEEAKSVLDEMMVEQTDLVRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LISTPPSDMLPTTEGGKSNAWLRQKNAGIYVRPRLFSPYVEEAKSVLDEMMVEQTDLVRL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 RMVRMSNVPDTLYMVNNAVPQCCHMISHQQISSNQSSPPSVVANEIPVPRLLIMKDMVRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RMVRMSNVPDTLYMVNNAVPQCCHMISHQQISSNQSSPPSVVANEIPVPRLLIMKDMVRR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 LQELRHTEQVQRAYALNCGEGATVSYEIQIRVLREFGLADAAAELLQNPHKFFPDERFGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQELRHTEQVQRAYALNCGEGATVSYEIQIRVLREFGLADAAAELLQNPHKFFPDERFGD 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 ESPLLTMRQPGRCRVNSTPPAETMFTDLDSFVAFHPPLPPPPPPYHPPATPIHNQLKAGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ESPLLTMRQPGRCRVNSTPPAETMFTDLDSFVAFHPPLPPPPPPYHPPATPIHNQLKAGW 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 KQRPPSQHPSRSFSYPCNHSLFHSRTAPKAGPPPVYLPSVKAAPPDCTSTAGLGRQTVAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KQRPPSQHPSRSFSYPCNHSLFHSRTAPKAGPPPVYLPSVKAAPPDCTSTAGLGRQTVAA 790 800 810 820 830 840 850 860 870 880 890 900 pF1KA1 AAATTTSTATAAAAAASEKQVRTQPVLNDLMPDIAVGVSTLSLKDRRLPELAVDTELSQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AAATTTSTATAAAAAASEKQVRTQPVLNDLMPDIAVGVSTLSLKDRRLPELAVDTELSQS 850 860 870 880 890 900 910 920 930 940 950 960 pF1KA1 VSEAGPGPPQHLSCIPQRHTHTSRKKHTLEQKTDTRENPQEYPDFYDFSNAACRPSTPAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSEAGPGPPQHLSCIPQRHTHTSRKKHTLEQKTDTRENPQEYPDFYDFSNAACRPSTPAL 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KA1 SRRTPSPSQGGYFGPDLYSHNKASPSGLKSAYLPGQTSPKKQEEARREYPLSPDGHLHRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRRTPSPSQGGYFGPDLYSHNKASPSGLKSAYLPGQTSPKKQEEARREYPLSPDGHLHRQ 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KA1 KNEPIHLDVVEQPPQRSDFPLAAPENASTGPAHVRGRTAVETDLTFGLTPNRPSLSACSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KNEPIHLDVVEQPPQRSDFPLAAPENASTGPAHVRGRTAVETDLTFGLTPNRPSLSACSS 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 pF1KA1 EAPEERSGRRLADSESLGHGAQRNTDLEREDSISRGRRSPSKPDFLYKKSAL :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EAPEERSGRRLADSESLGHGAQRNTDLEREDSISRGRRSPSKPDFLYKKSAL 1090 1100 1110 1120 1130 >>NP_001276062 (OMIM: 610386) BTB/POZ domain-containing (781 aa) initn: 5031 init1: 5031 opt: 5031 Z-score: 2778.1 bits: 525.4 E(85289): 5.3e-148 Smith-Waterman score: 5031; 99.9% identity (100.0% similar) in 746 aa overlap (387-1132:36-781) 360 370 380 390 400 410 pF1KA1 LVAGKPNMTRAEEAMELYHIALFLEFNMLAQGCEDIIAESISLDTLIAILKWSSHPYGSK .::::::::::::::::::::::::::::: NP_001 GAGADGGAGGGGGGGDGSGPSGSSSGGRSLRGCEDIIAESISLDTLIAILKWSSHPYGSK 10 20 30 40 50 60 420 430 440 450 460 470 pF1KA1 WVHRQALHFLCEEFSQVMTSDVFYELSKDHLLTAIQSDYLQASEQDILKYLIKWGEHQLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WVHRQALHFLCEEFSQVMTSDVFYELSKDHLLTAIQSDYLQASEQDILKYLIKWGEHQLM 70 80 90 100 110 120 480 490 500 510 520 530 pF1KA1 KRIADREPNLLSGTAHSVNKRGVKRRDLDMEELREILSSLLPFVRIEHILPINSEVLSDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KRIADREPNLLSGTAHSVNKRGVKRRDLDMEELREILSSLLPFVRIEHILPINSEVLSDA 130 140 150 160 170 180 540 550 560 570 580 590 pF1KA1 MKRGLISTPPSDMLPTTEGGKSNAWLRQKNAGIYVRPRLFSPYVEEAKSVLDEMMVEQTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKRGLISTPPSDMLPTTEGGKSNAWLRQKNAGIYVRPRLFSPYVEEAKSVLDEMMVEQTD 190 200 210 220 230 240 600 610 620 630 640 650 pF1KA1 LVRLRMVRMSNVPDTLYMVNNAVPQCCHMISHQQISSNQSSPPSVVANEIPVPRLLIMKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LVRLRMVRMSNVPDTLYMVNNAVPQCCHMISHQQISSNQSSPPSVVANEIPVPRLLIMKD 250 260 270 280 290 300 660 670 680 690 700 710 pF1KA1 MVRRLQELRHTEQVQRAYALNCGEGATVSYEIQIRVLREFGLADAAAELLQNPHKFFPDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MVRRLQELRHTEQVQRAYALNCGEGATVSYEIQIRVLREFGLADAAAELLQNPHKFFPDE 310 320 330 340 350 360 720 730 740 750 760 770 pF1KA1 RFGDESPLLTMRQPGRCRVNSTPPAETMFTDLDSFVAFHPPLPPPPPPYHPPATPIHNQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RFGDESPLLTMRQPGRCRVNSTPPAETMFTDLDSFVAFHPPLPPPPPPYHPPATPIHNQL 370 380 390 400 410 420 780 790 800 810 820 830 pF1KA1 KAGWKQRPPSQHPSRSFSYPCNHSLFHSRTAPKAGPPPVYLPSVKAAPPDCTSTAGLGRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KAGWKQRPPSQHPSRSFSYPCNHSLFHSRTAPKAGPPPVYLPSVKAAPPDCTSTAGLGRQ 430 440 450 460 470 480 840 850 860 870 880 890 pF1KA1 TVAAAAATTTSTATAAAAAASEKQVRTQPVLNDLMPDIAVGVSTLSLKDRRLPELAVDTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TVAAAAATTTSTATAAAAAASEKQVRTQPVLNDLMPDIAVGVSTLSLKDRRLPELAVDTE 490 500 510 520 530 540 900 910 920 930 940 950 pF1KA1 LSQSVSEAGPGPPQHLSCIPQRHTHTSRKKHTLEQKTDTRENPQEYPDFYDFSNAACRPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSQSVSEAGPGPPQHLSCIPQRHTHTSRKKHTLEQKTDTRENPQEYPDFYDFSNAACRPS 550 560 570 580 590 600 960 970 980 990 1000 1010 pF1KA1 TPALSRRTPSPSQGGYFGPDLYSHNKASPSGLKSAYLPGQTSPKKQEEARREYPLSPDGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TPALSRRTPSPSQGGYFGPDLYSHNKASPSGLKSAYLPGQTSPKKQEEARREYPLSPDGH 610 620 630 640 650 660 1020 1030 1040 1050 1060 1070 pF1KA1 LHRQKNEPIHLDVVEQPPQRSDFPLAAPENASTGPAHVRGRTAVETDLTFGLTPNRPSLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LHRQKNEPIHLDVVEQPPQRSDFPLAAPENASTGPAHVRGRTAVETDLTFGLTPNRPSLS 670 680 690 700 710 720 1080 1090 1100 1110 1120 1130 pF1KA1 ACSSEAPEERSGRRLADSESLGHGAQRNTDLEREDSISRGRRSPSKPDFLYKKSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ACSSEAPEERSGRRLADSESLGHGAQRNTDLEREDSISRGRRSPSKPDFLYKKSAL 730 740 750 760 770 780 >>XP_016876927 (OMIM: 610386) PREDICTED: BTB/POZ domain- (657 aa) initn: 4438 init1: 4438 opt: 4438 Z-score: 2453.9 bits: 465.1 E(85289): 6e-130 Smith-Waterman score: 4438; 100.0% identity (100.0% similar) in 657 aa overlap (476-1132:1-657) 450 460 470 480 490 500 pF1KA1 HLLTAIQSDYLQASEQDILKYLIKWGEHQLMKRIADREPNLLSGTAHSVNKRGVKRRDLD :::::::::::::::::::::::::::::: XP_016 MKRIADREPNLLSGTAHSVNKRGVKRRDLD 10 20 30 510 520 530 540 550 560 pF1KA1 MEELREILSSLLPFVRIEHILPINSEVLSDAMKRGLISTPPSDMLPTTEGGKSNAWLRQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MEELREILSSLLPFVRIEHILPINSEVLSDAMKRGLISTPPSDMLPTTEGGKSNAWLRQK 40 50 60 70 80 90 570 580 590 600 610 620 pF1KA1 NAGIYVRPRLFSPYVEEAKSVLDEMMVEQTDLVRLRMVRMSNVPDTLYMVNNAVPQCCHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NAGIYVRPRLFSPYVEEAKSVLDEMMVEQTDLVRLRMVRMSNVPDTLYMVNNAVPQCCHM 100 110 120 130 140 150 630 640 650 660 670 680 pF1KA1 ISHQQISSNQSSPPSVVANEIPVPRLLIMKDMVRRLQELRHTEQVQRAYALNCGEGATVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISHQQISSNQSSPPSVVANEIPVPRLLIMKDMVRRLQELRHTEQVQRAYALNCGEGATVS 160 170 180 190 200 210 690 700 710 720 730 740 pF1KA1 YEIQIRVLREFGLADAAAELLQNPHKFFPDERFGDESPLLTMRQPGRCRVNSTPPAETMF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YEIQIRVLREFGLADAAAELLQNPHKFFPDERFGDESPLLTMRQPGRCRVNSTPPAETMF 220 230 240 250 260 270 750 760 770 780 790 800 pF1KA1 TDLDSFVAFHPPLPPPPPPYHPPATPIHNQLKAGWKQRPPSQHPSRSFSYPCNHSLFHSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TDLDSFVAFHPPLPPPPPPYHPPATPIHNQLKAGWKQRPPSQHPSRSFSYPCNHSLFHSR 280 290 300 310 320 330 810 820 830 840 850 860 pF1KA1 TAPKAGPPPVYLPSVKAAPPDCTSTAGLGRQTVAAAAATTTSTATAAAAAASEKQVRTQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TAPKAGPPPVYLPSVKAAPPDCTSTAGLGRQTVAAAAATTTSTATAAAAAASEKQVRTQP 340 350 360 370 380 390 870 880 890 900 910 920 pF1KA1 VLNDLMPDIAVGVSTLSLKDRRLPELAVDTELSQSVSEAGPGPPQHLSCIPQRHTHTSRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLNDLMPDIAVGVSTLSLKDRRLPELAVDTELSQSVSEAGPGPPQHLSCIPQRHTHTSRK 400 410 420 430 440 450 930 940 950 960 970 980 pF1KA1 KHTLEQKTDTRENPQEYPDFYDFSNAACRPSTPALSRRTPSPSQGGYFGPDLYSHNKASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KHTLEQKTDTRENPQEYPDFYDFSNAACRPSTPALSRRTPSPSQGGYFGPDLYSHNKASP 460 470 480 490 500 510 990 1000 1010 1020 1030 1040 pF1KA1 SGLKSAYLPGQTSPKKQEEARREYPLSPDGHLHRQKNEPIHLDVVEQPPQRSDFPLAAPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGLKSAYLPGQTSPKKQEEARREYPLSPDGHLHRQKNEPIHLDVVEQPPQRSDFPLAAPE 520 530 540 550 560 570 1050 1060 1070 1080 1090 1100 pF1KA1 NASTGPAHVRGRTAVETDLTFGLTPNRPSLSACSSEAPEERSGRRLADSESLGHGAQRNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NASTGPAHVRGRTAVETDLTFGLTPNRPSLSACSSEAPEERSGRRLADSESLGHGAQRNT 580 590 600 610 620 630 1110 1120 1130 pF1KA1 DLEREDSISRGRRSPSKPDFLYKKSAL ::::::::::::::::::::::::::: XP_016 DLEREDSISRGRRSPSKPDFLYKKSAL 640 650 >>NP_060637 (OMIM: 610386) BTB/POZ domain-containing pro (410 aa) initn: 2547 init1: 2547 opt: 2548 Z-score: 1420.3 bits: 273.2 E(85289): 2.3e-72 Smith-Waterman score: 2548; 98.7% identity (99.0% similar) in 393 aa overlap (1-393:1-393) 10 20 30 40 50 60 pF1KA1 MGANASNYPHSCSPRVGGNSQAQQTFIGTSSYSQQGYGCESKLYSLDHGHEKPQDKKKRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 MGANASNYPHSCSPRVGGNSQAQQTFIGTSSYSQQGYGCESKLYSLDHGHEKPQDKKKRT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 SGLATLKKKFIKRRKSNRSADHAKQMRELLSGWDVRDVNALVEEYEGTSALKELSLQASL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 SGLATLKKKFIKRRKSNRSADHAKQMRELLSGWDVRDVNALVEEYEGTSALKELSLQASL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 ARPEARTLQKDMADLYEYKYCTDVDLIFQETCFPVHRAILAARCPFFKTLLSSSPEYGAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 ARPEARTLQKDMADLYEYKYCTDVDLIFQETCFPVHRAILAARCPFFKTLLSSSPEYGAE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 IIMDINTAGIDMPMFSALLHYLYTGEFGMEDSRFQNVDILVQLSEEFGTPNSLDVDMRGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 IIMDINTAGIDMPMFSALLHYLYTGEFGMEDSRFQNVDILVQLSEEFGTPNSLDVDMRGL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 FDYMCYYDVVLSFSSDSELVEAFGGNQNCLDEELKAHKAVISARSPFFRNLLQRRIRTGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 FDYMCYYDVVLSFSSDSELVEAFGGNQNCLDEELKAHKAVISARSPFFRNLLQRRIRTGE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 EITDRTLRTPTRIILDESIIPKKYATVILHCMYTDVVDLSVLHCSPSVGSLSEVQALVAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 EITDRTLRTPTRIILDESIIPKKYATVILHCMYTDVVDLSVLHCSPSVGSLSEVQALVAG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 KPNMTRAEEAMELYHIALFLEFNMLAQGCEDIIAESISLDTLIAILKWSSHPYGSKWVHR ::::::::::::::::::::::::::: .: NP_060 KPNMTRAEEAMELYHIALFLEFNMLAQEETTVIRPACAAELSNSCLLPQS 370 380 390 400 410 430 440 450 460 470 480 pF1KA1 QALHFLCEEFSQVMTSDVFYELSKDHLLTAIQSDYLQASEQDILKYLIKWGEHQLMKRIA 1132 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 11:15:43 2016 done: Thu Nov 3 11:15:45 2016 Total Scan time: 18.710 Total Display time: 0.150 Function used was FASTA [36.3.4 Apr, 2011]