FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1579, 678 aa 1>>>pF1KA1579 678 - 678 aa - 678 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.0085+/-0.000964; mu= 14.6297+/- 0.059 mean_var=174.3365+/-36.779, 0's: 0 Z-trim(111.2): 43 B-trim: 0 in 0/52 Lambda= 0.097136 statistics sampled from 12140 (12176) to 12140 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.714), E-opt: 0.2 (0.374), width: 16 Scan time: 4.270 The best scores are: opt bits E(32554) CCDS41345.1 RAVER2 gene_id:55225|Hs108|chr1 ( 678) 4504 643.8 2.4e-184 CCDS45960.1 RAVER1 gene_id:125950|Hs108|chr19 ( 756) 1353 202.3 2.2e-51 >>CCDS41345.1 RAVER2 gene_id:55225|Hs108|chr1 (678 aa) initn: 4504 init1: 4504 opt: 4504 Z-score: 3423.2 bits: 643.8 E(32554): 2.4e-184 Smith-Waterman score: 4504; 100.0% identity (100.0% similar) in 678 aa overlap (1-678:1-678) 10 20 30 40 50 60 pF1KA1 MAAAAGDGGGEGGAGLGSAAGLGPGPGLRGQGPSAEAHEGAPDPMPAALHPEEVAARLQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 MAAAAGDGGGEGGAGLGSAAGLGPGPGLRGQGPSAEAHEGAPDPMPAALHPEEVAARLQR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 MQRELSNRRKILVKNLPQDSNCQEVHDLLKDYDLKYCYVDRNKRTAFVTLLNGEQAQNAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 MQRELSNRRKILVKNLPQDSNCQEVHDLLKDYDLKYCYVDRNKRTAFVTLLNGEQAQNAI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 QMFHQYSFRGKDLIVQLQPTDALLCITNVPISFTSEEFEELVRAYGNIERCFLVYSEVTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 QMFHQYSFRGKDLIVQLQPTDALLCITNVPISFTSEEFEELVRAYGNIERCFLVYSEVTG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 HSKGYGFVEYMKKDFAAKARLELLGRQLGASALFAQWMDVNLLASELIHSKCLCIDKLPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 HSKGYGFVEYMKKDFAAKARLELLGRQLGASALFAQWMDVNLLASELIHSKCLCIDKLPS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 DYRDSEELLQIFSSVHKPVFCQLAQDEGSYVGGFAVVEYSTAEQAEEVQQAADGMTIKGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 DYRDSEELLQIFSSVHKPVFCQLAQDEGSYVGGFAVVEYSTAEQAEEVQQAADGMTIKGS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 KVQVSFCAPGAPGRSTLAALIAAQRVMHSNQKGLLPEPNPVQIMKSLNNPAMLQVLLQPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 KVQVSFCAPGAPGRSTLAALIAAQRVMHSNQKGLLPEPNPVQIMKSLNNPAMLQVLLQPQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 LCGRAVKPAVLGTPHSLPHLMNPSISPAFLHLNKAHQNLSHIPLAQQQLMKFENIHTNNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 LCGRAVKPAVLGTPHSLPHLMNPSISPAFLHLNKAHQNLSHIPLAQQQLMKFENIHTNNK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 PGLLGEPPAVVLQTALGIGSVLPLKKELGHHHGEAHKTSSLIPTQTTITAGMGMLPFFPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 PGLLGEPPAVVLQTALGIGSVLPLKKELGHHHGEAHKTSSLIPTQTTITAGMGMLPFFPN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 QHIAGQAGPGHSNTQEKQPATVGMAEGNFSGSQPYLQSFPNLAAGSLLVGHHKQQQSQPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 QHIAGQAGPGHSNTQEKQPATVGMAEGNFSGSQPYLQSFPNLAAGSLLVGHHKQQQSQPK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 GTEISSGAASKNQTSLLGEPPKEIRLSKNPYLNLASVLPSVCLSSPASKTTLHKTGIASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 GTEISSGAASKNQTSLLGEPPKEIRLSKNPYLNLASVLPSVCLSSPASKTTLHKTGIASS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 ILDAISQGSESQHALEKCIAYSPPFGDYAQVSSLRNEKRGSSYLISAPEGGSVECVDQHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 ILDAISQGSESQHALEKCIAYSPPFGDYAQVSSLRNEKRGSSYLISAPEGGSVECVDQHS 610 620 630 640 650 660 670 pF1KA1 QGTGAYYMETYLKKKRVY :::::::::::::::::: CCDS41 QGTGAYYMETYLKKKRVY 670 >>CCDS45960.1 RAVER1 gene_id:125950|Hs108|chr19 (756 aa) initn: 1519 init1: 1276 opt: 1353 Z-score: 1036.1 bits: 202.3 E(32554): 2.2e-51 Smith-Waterman score: 1448; 45.2% identity (67.0% similar) in 573 aa overlap (22-589:30-544) 10 20 30 40 50 pF1KA1 MAAAAGDGGGEGGAGLGSAAGLGPGPGLRGQGPSAEAHEGAPDPMPAALHPE :.: : . .. .: :.. ::. : :: CCDS45 MPLRPGSLVPEGAGFPKMAADVSVTHRPPLSPKSGAEVEAGDA-AERRAPEEELPPLDPE 10 20 30 40 50 60 70 80 90 100 110 pF1KA1 EVAARLQRMQRELSNRRKILVKNLPQDSNCQEVHDLLKDYDLKYCYVDRNKRTAFVTLLN :. ::.. .:.. ::::::...:: : . :::::::.::.::::.::. : :::::::: CCDS45 EIRKRLEHTERQFRNRRKILIRGLPGDVTNQEVHDLLSDYELKYCFVDKYKGTAFVTLLN 60 70 80 90 100 110 120 130 140 150 160 170 pF1KA1 GEQAQNAIQMFHQYSFRGKDLIVQLQPTDALLCITNVPISFTSEEFEELVRAYGNIERCF ::::. ::. ::: .: ..: :::::::::::..:.: :.:...:::::: .:..:::: CCDS45 GEQAEAAINAFHQSRLRERELSVQLQPTDALLCVANLPPSLTQQQFEELVRPFGSLERCF 120 130 140 150 160 170 180 190 200 210 220 230 pF1KA1 LVYSEVTGHSKGYGFVEYMKKDFAAKARLELLGRQLGASALFAQWMDVNLLASELIHSKC ::::: ::.::::::.:::::: ::.:. .:::. :: .:...: :.. :. :.::.: CCDS45 LVYSERTGQSKGYGFAEYMKKDSAARAKSDLLGKPLGPRTLYVHWTDAGQLTPALLHSRC 180 190 200 210 220 230 240 250 260 270 280 290 pF1KA1 LCIDKLPSDYRDSEELLQIFSSVHKPVFCQLAQDEGSYVGGFAVVEYSTAEQAEEVQQAA ::.:.:: . : . : . .:.::.:.::::: . . . ::::.:: :::.:::.:: : CCDS45 LCVDRLPPGFNDVDALCRALSAVHSPTFCQLACGQDGQLKGFAVLEYETAEMAEEAQQQA 240 250 260 270 280 290 300 310 320 330 340 350 pF1KA1 DGMTIKGSKVQVSFCAPGAPGRSTLAALIAAQRVMHSNQKGLLPEPNPVQIMKSLNNPAM ::... ::...::::::: :::: :::::::: . . :::::::: .:....:. : CCDS45 DGLSLGGSHLRVSFCAPGPPGRSMLAALIAAQATALNRGKGLLPEPNILQLLNNLGPSAS 300 310 320 330 340 350 360 370 380 390 400 410 pF1KA1 LQVLLQPQLCGRAV-KPAVLGTPHSLPHLMNPSISPAFLHLNKAHQNLSHIPLAQQQLMK ::.::.: : : : : ..::.: ..: : .:..: :.:.: : : .: CCDS45 LQLLLNPLLHGSAGGKQGLLGAPPAMPLLNGPALSTALLQLA-----------LQTQGQK 360 370 380 390 400 420 430 440 450 460 470 pF1KA1 FENIHTNNKPGLLGEPPAVVLQTALGIGSVLPLKKELGHHHGEAHKTSSLIPTQTTITAG :::.::. : .:: : . :: :: : :: CCDS45 --------KPGILGDSPLGALQP--GAQPANPLLGEL--------------P------AG 410 420 430 480 490 500 510 520 pF1KA1 MGMLPFFPNQHIAGQAGPGHSNTQEKQPATVGMAEGN---FSGSQPYLQSFPNLAAGSLL :. : .: .. :. : :...: : :. .. . : : : : .: CCDS45 GGLPPELPPRR--GKPPP-------LLPSVLGPAGGDREALGLGPPAAQLTPPPAPVGL- 440 450 460 470 480 530 540 550 560 570 580 pF1KA1 VGHHKQQQSQPKGTEISSGA-ASKNQTSLLGEPPKEIRLSKNPYLNLASVLPSVCLSSPA . : .: . .:: . .::::::::. :. :::::: :.::. :.. CCDS45 ------RGSGLRGLQKDSGPLPTPPGVSLLGEPPKDYRIPLNPYLNLHSLLPASNLAGKE 490 500 510 520 530 540 590 600 610 620 630 640 pF1KA1 SKTTLHKTGIASSILDAISQGSESQHALEKCIAYSPPFGDYAQVSSLRNEKRGSSYLISA .. CCDS45 ARGWGGAGRSRRPAEGPPTNPPAPGGGSSSSKAFQLKSRLLSPLSSARLPPEPGLSDSYS 550 560 570 580 590 600 678 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 01:39:14 2016 done: Fri Nov 4 01:39:15 2016 Total Scan time: 4.270 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]